Abstract: The invention is directed to latent reactive and polymerizable derivatives of fluorescent stilbene-based compounds. The compounds can be used to provide articles with a fluorescence property, such as medical devices (e.g., catheters). The fluorescent compounds can be used in association with polymers, or can be incorporated into polymers, and the polymers used in a coating composition on the article surface. The compounds allow for visual or machine inspection of coating properties such as uniformity of coverage.

Abstract: The technology described herein relates to methods of inducing cell death. The technology described herein further relates to treating conditions including cancers and autoimmune diseases comprising administering inhibitors of double strand break repair. Also described herein are inhibitors of double strand break repair and methods of screening for such inhibitors.

Abstract: A process for preparing substituted aromatic and heteroaromatic aldehydes or carboxylic acids of the formula in which R1 and R2 are H, C1-C4 alkyl, C1-C4 alkoxy, OH, NO2, CN, COOH, CONH2, COOR, NH2, SO3H or halogen and R is C1-C4 alkyl and where R1 and R2 are not simultaneously H, X is C or N and Z is CHO or COOH, from the corresponding symmetric stilbene compounds of the formula in which R1, R2 and X are as defined above, by aqueous ozonolysis and subsequent isolation of an aldehyde or oxidation to give the corresponding carboxylic acid.

Abstract: A class of novel phenyl acetamides is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

Abstract: This invention pertains to novel salt forms of trophenylethylene compound, such as 3-[4(1,2-diphenyl-but-1-enyl)-phenyl]-acrylic acid, as selective estrogen receptor modulators. This invention also provides methods for the treatment and/or prevention of breast, uterine, ovarian, prostrate and colon cancer, osteoporosis, cardiovascular disease, and benign proliferative disorders, as well as pharmaceutical compositions of the compounds of the present invention.

Abstract: A substrate for solid phase synthesis comprising a solid phase-linker combination of the formula I is disclosed. Also disclosed are processes for preparing the substrate and chemical intermediates useful therein. Among the novel intermediates are compounds of the formula II wherein R1 is —NO2 or —CHO; R2 is —OCH3, —CHO or —H; R3 is chosen from the group consisting of hydroxyl, the residue of a solid support having a plurality of amino groups, and the residue of an ester, and n=1 or 3-12.

Abstract: Sterically hindered phenols of formula (1) are disclosed. These antioxidants are suitable for enhancing the thermal and photochemical stability of undyed and dyed polyamide fibre materials. They are distinguished by superior exhaustion which is almost independent of the pH.

Abstract: Sulfonic acid stilbenes are disclosed which block the infection of cells by HSV, HIV and CMV.