Benzene Ring Containing Patents (Class 564/139)
  • Patent number: 4442029
    Abstract: A process for the preparation of acid amides, comprising reacting a carboxylic acid and an amine in the presence of an isonitrile, wherein the isonitrile has at least one hetero-atom in the substituent present in the above-mentioned isonitrile group. The isonitrile is preferably morpholino-ethyl isocyanide, a new chemical compound.
    Type: Grant
    Filed: January 25, 1983
    Date of Patent: April 10, 1984
    Inventors: Dieter Marquarding, Helmut Aigner
  • Patent number: 4426325
    Abstract: To prepare compounds containing carboxylic acid amide groups, in particular peptides, there are reacted compounds containing a carboxy group, in the presence of dialkylphosphinic acid anhydrides with compounds containing a free amino group.
    Type: Grant
    Filed: January 15, 1982
    Date of Patent: January 17, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Hans-Jerg Kleiner
  • Patent number: 4421931
    Abstract: Anthranilic acid amides are prepared by mixing phthalamic acid with a caustic alkali solution, a catalyst and a hypohalite, allowing the mixture to stand for from 1 to 1,000 seconds, then introducing the amine and thereafter addig acid until the pH of the mixture is from 6 to 8.The anthranilic acid amides obtainable by the process of the invention are valuable starting materials for the preparation of dyes, scents and pesticides.
    Type: Grant
    Filed: January 11, 1982
    Date of Patent: December 20, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Tonne, Winfried Ludwig, Gerhard Kilpper, Johannes Grimmer
  • Patent number: 4410700
    Abstract: In a short total synthesis of morphinan compounds, derivatives of 1-benzyl-1,2,3,4-tetrahydroisoquinoline are produced. Certain of these compounds, although highly aromatic and functionalized, can be optically resolved. The optically active enantiomers can serve as important intermediates for both natural and unnatural opioids.
    Type: Grant
    Filed: May 20, 1981
    Date of Patent: October 18, 1983
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Kenner C. Rice
  • Patent number: 4379928
    Abstract: Alkyl amides have been synthesized from cyclic anhydrides, carboxyl acids and their esters by contacting them with an amine carbamic acid salt.
    Type: Grant
    Filed: March 4, 1981
    Date of Patent: April 12, 1983
    Assignee: Union Carbide Corporation
    Inventor: Spyros Theodoropulos
  • Patent number: 4331592
    Abstract: What is disclosed is a method of making a carboxylic acid amide, including a peptide, by reacting a compound having a free amino group with a compound having a free carboxy group in the presence of an anhydride of an alkane-phosphonic acid.
    Type: Grant
    Filed: January 16, 1980
    Date of Patent: May 25, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Hans-Jerg Kleiner
  • Patent number: 4329462
    Abstract: Carboxylic amides can be produced simply and in good yield by reacting primary alcohols with at least one compound selected from ammonia, primary amines, and secondary amines, in the presence of a molecular oxygen-containing gas and a palladium or platinum catalyst under oxidative conditions.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: May 11, 1982
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Nobuhiro Tamura, Yohei Fukuoka, Joji Nishikido, Setsuo Yamamatsu, Yoshio Suzuki
  • Patent number: 4326055
    Abstract: This invention is directed to 5,6,7,8-tetrahydro-naphthyl or indanyl stilbene derivatives which are useful as tumor inhibiting agents, in the treatment of neoplasms, dermatological conditions and rheumatic illnesses.
    Type: Grant
    Filed: December 15, 1978
    Date of Patent: April 20, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Peter Loeliger
  • Patent number: 4323692
    Abstract: This process relates to the oxidation of phenoxytoluenes to phenoxybenzoic acids utilizing a hydrogen peroxide activated, bromide promoted cobalt catalyst which can be performed at atmospheric pressure and at moderate temperatures. These phenoxybenzoic acids can then be esterified and selectively nitrated to give the corresponding 2-nitro-5-(substituted)phenoxybenzoic acid esters. Alternatively the acids can be nitrated and then esterified.
    Type: Grant
    Filed: August 4, 1978
    Date of Patent: April 6, 1982
    Assignee: Rohm and Haas Company
    Inventor: Charles M. Tanger
  • Patent number: 4286105
    Abstract: An inexpensive and nonhazardous process for the preparation of an amide wherein an organic acid reacting with an aryl amine to form an intermediate hydroxy aryl amide and then dehydrating the hydroxy aryl amide to form a .alpha., .beta. unsaturated amide.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: August 25, 1981
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Dane K. Parker