Abstract: This disclosure describes novel 4-(polyfluoroalkylamino)phenyl compounds useful as hypolipidemic and antiatherosclerotic agents.

Abstract: Novel .alpha.-aminoacetamides are powerful stabilizers for organic materials subject to oxygen and heat degradation, and particularly for synthetic natural rubber and synthetic ester lubricants. A wide range of substituents on the amine and amide N atoms, and also on the saturated carbon atom, yields an array of stabilizers having a wide range of compatibility in compositions comprising various synthetic resinous compounds to be stabilized.Novel syntheses are provided utilizing at least one amine nucleophilic agent, a dichlorocarbene ion generating agent, and an alkoxide ion generating agent, which together in the presence of aqueous alkali and an onium salt, yield novel .alpha.-aminoacetamides in which a wide choice of substituents may be introduced. The nucleophilic agent may be a primary or secondary amine, or one of each. The dichlorocarbene ion generating agent is a haloform. The alkoxide ion generating agent may be a ketone, an aldehyde, or a cyanohydrin which reacts with the haloform. An .alpha.

Abstract: The present invention relates to halo-substituted 2,2 dimethylcyclopropaneamides, useful as intermediates for the preparation of imidates having pesticidal properties.

Abstract: Disclosed is a process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid (Diclofenac) or its pharmacologically acceptable acid addition salt, which comprises hydrolyzing an N,N-disubstituted-o-(2,6-dichloroanilino)phenylacetamide derivative with an alkali. Also a novel intermediate for use in the preparation of Diclofenac, that is, an N,N-disubstituted-o-halogenophenylacetamide in which the halogen is iodine or bromine, is disclosed.

Abstract: 2-Aryl-1,3-cyclopentanedione compounds and their alkali metal and ammonium salts exhibit outstanding herbicidal and acaricidal activity.

Abstract: Compounds having hypolipidaemic activity which are substituted aralkylanilines, their preparation and pharmaceutical compositions containing them.

Abstract: Disclosed are new azo dyes prepared by diazotizing selected substituted anilines and coupling with aniline couplers containing sulfate ester groups. These dyes impart fast yellow to reddish-orange shades on polyamide fibers and also color cellulose acetate and wool. The dyes have the following general formula: ##STR1## wherein R is selected from a variety of groups such as alkyl, alkoxy, aryl, cycloalkyl, aryloxy, NH.sub.2, and NH alkyl; X is hydrogen, halogen, alkyl, or the like; Y is hydrogen or halogen; R.sub.1 is selected from groups such as hydrogen, alkyl, alkoxy, halogen, acylamido, alkylthio, and aryloxy; R.sub.2 is selected from such groups as hydrogen, alkyl, aryl and cycloalkyl; Z is a linking group such as alkylene; M is H.sup.+, Na.sup.+, K.sup.+, or NH.sub.4.sup.+ ; and m is 0, 1, or 2.

Abstract: N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto, useful as antihypertensive agents, are prepared by reaction of an N-substituted aniline with a polyfluoroacetone.

Abstract: A process for the preparation of an anthranilamide of the formula ##STR1## in which R.sub.1 and R.sub.2 each independently is hydrogen orC.sub.1 to C.sub.4 alkyl, or R.sub.1 and R.sub.2, together with the nitrogen atom to which they are bonded, form a heterocyclic ring,comprising reacting isatoic anhydride of the formula ##STR2## with an approximately equimolar amount of an amine of the formula ##STR3## in water at a pH of about 7 to 10.5 and a temperature of about 20.degree. to 100.degree. C. Advantageously the reaction is effected in the presence of a buffer system comprising an amine of the formula ##STR4## plus at least one of a hydrohalide and carbonic acid salt of such amine, e.g. ammonia or a lower alkyl amine plus the corresponding hydrochloride and/or carbonate.

Abstract: Substantive sunscreen agents which are neutralized or quaternary ammonium salts of esters or amides of p-aminobenzoic acid, p-nitrobenzoic acid or salicylic acid with choline, lecithin, hydroxyalkyl-substituted imidazoles, 2,2-dialkylamino alkanols or alkylamines, pyridinesulfonamide, or colaminomethylformyl chloride; or omega halogenoalkylethers of salicylic acid quaternized with tertiary amines. This is a continuation of application Ser. No. 339,974 filed Mar. 12, 1973, which is a divisional application of Ser. No. 130,533, filed Apr. 1, 1971, both now abandoned.

Abstract: Aromatic amines are obtained in high yield and purity by treating the corresponding cyclohex-2-en-1-on-oxime hydrochlorides with the at least threefold molar amount of acetic anhydride.

Abstract: The present invention relates to new N-substituted anilines which correspond to the general formula: ##STR1## in which R.sub.1 represents an alkyl radical or substituted alkyl radical, R.sub.2 represents a hydrogen atom, an alkyl radical or substituted alkyl radical, R.sub.3 represents a cyano, carbamoyl, carboxy or carbalkoxy radical and R.sub.4 represents a hydrogen or halogen atom or an alkyl or alkoxy radical. These compounds are valuable intermediates for the preparation of coloring materials, especially as coupling compounds for the synthesis of azo dyes.

Abstract: An o-(N-allyl-2,6-dichloroanilino)phenylacetic acid derivative represented by the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, individually represent a hydrogen atom, a halogen atom or an alkyl group; Y represents a hydroxyl group, an alkoxyl group, a --OM.sup.1 group in which M.sup.1 is an alkali metal atom, a --OM.sub.1/2.sup.2 group in which M.sup.2 is an alkaline earth metal atom, an amino group having the formula --NR.sup.5 R.sup.6 in which R.sup.5 and R.sup.6, which may be the same or different, individually represent a hydrogen atom or an alkyl group, or a hydroxylamino group,and processes for preparing the same.

Abstract: Covers certain aromatic-amine amides which comprise the reaction product of a bis-amino-n propyl ether and an isatoic anhydride of the formula: ##STR1## where R is selected from the group consisting of hydrogen, alkyl, nitro, halo, hydroxy, amino, and cyano, and n is a number of 1-4. Also covers the use of said compounds as chain-extenders in polyurethane compositions. Such chain-extenders provide for the production of polyurethane elastomers having improved tensile strength, tear strength and elongation properties.

Abstract: 2-Amino-5-chloro-N-(2,2-dimethoxyethyl)benzamide is useful as a muscle relaxant.

Abstract: Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds of the formulae: ##STR1## wherein R.sub.1 is a saturated or unsaturated hydrocarbon radical of 8-19 carbon atoms which may be branched or unbranched and which may contain one or more radicals selected from the group consisting of saturated or unsaturated cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; J is ##STR2## wherein Z is inter alia hydrogen, loweralkyl, hydroxy, loweralkoxy and loweralkoxyalkoxy, or J is carboxyloweralkyl, carboxyloweralkenyl, carboxyloweralkynyl, carboalkoxyloweralkyl, carboalkoxyloweralkenyl or carboalkoxyloweralkynyl.