Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds
Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds of the formulae: ##STR1## wherein R.sub.1 is a saturated or unsaturated hydrocarbon radical of 8-19 carbon atoms which may be branched or unbranched and which may contain one or more radicals selected from the group consisting of saturated or unsaturated cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; J is ##STR2## wherein Z is inter alia hydrogen, loweralkyl, hydroxy, loweralkoxy and loweralkoxyalkoxy, or J is carboxyloweralkyl, carboxyloweralkenyl, carboxyloweralkynyl, carboalkoxyloweralkyl, carboalkoxyloweralkenyl or carboalkoxyloweralkynyl.
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Description
Patent History
Patent number: T100403
Type: Grant
Filed: Oct 17, 1979
Date of Patent: Mar 3, 1981
Assignee: American Cyanamid Company (Stamford, CT)
Inventor: Robert G. Shepherd (South Nyack, NY)
Application Number: 6/85,650
Type: Grant
Filed: Oct 17, 1979
Date of Patent: Mar 3, 1981
Assignee: American Cyanamid Company (Stamford, CT)
Inventor: Robert G. Shepherd (South Nyack, NY)
Application Number: 6/85,650
Classifications
Current U.S. Class:
424/319;
260/3458R;
260/34859;
424/263;
424/267;
424/270;
424/278;
424/283;
424/307;
424/310;
424/324;
At 1-position (546/226);
Unsaturated Hydrocarbyl Side Chain (546/350);
The -c(=x)- Is Part Of A -c(=x)x- Group, Wherein The X's Are The Same Or Diverse Chalcogens (548/201);
Nitrogen In Acid Moiety Other Than As Nitroso Or Isocyanate (e.g., Amino Acid Esters, Etc.) (560/19);
Polyoxy Alcohol Moiety (560/50);
Carboxyl, Or Salt Thereof, Bonded Directly To A Ring (562/458);
Benzene Ring Containing (568/424);
Carbonyl, Cyano, Nitro, Nitroso, Halogen, Or Sulfur Attached Directly To The Sulfonamide Nitrogen Or To An Amino Nitrogen In A Substituent E By Nonionic Bonding (564/91);
Benzene Ring In A Substituent E (564/99);
Substituent Q Contains Benzene Ring (564/149);
Amino Nitrogen, Not Bonded Directly To Carbonyl, Containing (564/157);
Nitrogen In Substituent Q (564/163);
Hydroxy, Bonded Directly To Carbon, Or Ether In Substituent Q (h Of -oh May Be Replaced By A Substituted Or Unsubstituted Ammonium Ion Or A Group Ia Or Iia Light Metal) (564/167)
International Classification: A61K 31195;
International Classification: A61K 31195;
