Carbonyl In Substituent Q Patents (Class 564/199)
  • Patent number: 4448988
    Abstract: The invention relates to new 2-ketosulfonamides of the general formula ##STR1## and to a process for their preparation, which process comprises oxidizing compounds of the general formulaR--CHOH--CH.sub.2 --SO.sub.2 NH.sub.2with manganese dioxide in a readily volatile, oxidation-stable organic solvent, preferably acetone or acetonitrile.
    Type: Grant
    Filed: April 21, 1982
    Date of Patent: May 15, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Dieter Gunther
  • Patent number: 4307112
    Abstract: 9-deoxy-9A-methylene-isosteres of PGI.sub.2, including processes for their preparation and pharmaceutical and veterinary compositions containing same, are disclosed. The compounds are useful as therapeutic agents, for example as anti-aggregating agents, disaggregating agents, and as vasodilators.
    Type: Grant
    Filed: February 26, 1980
    Date of Patent: December 22, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Carmelo Gandolfi, Carlo Passarotti, William Fava, Angelo Fumagalli, Franco Faustini, Roberto Ceserani
  • Patent number: 4247712
    Abstract: There is disclosed methods and compositions for inhibiting or preventing the growth of microorganisms in aqueous systems wherein the growth is inhibited or prevented by the presence of an effective amount of a 2-chloro-3-oxobutyramide derivative.
    Type: Grant
    Filed: November 8, 1979
    Date of Patent: January 27, 1981
    Assignees: Givaudan Corporation, Hoffmann-La Roche Inc.
    Inventors: Harold A. Brandman, Milton Manowitz, David L. Coffen
  • Patent number: 4235818
    Abstract: A process for the production of .alpha.-monochloroacetoacetic acid monomethylamide is disclosed which comprises chlorinating acetoacetic acid monomethylamide in the presence of urea and a water-soluble alkali metal salt or ammonium salt at a temperature of between -20.degree. and +10.degree. C. with 80-95% of the equivalent amount of chlorine; neutralizing the reaction mixture; separating the precipitated .alpha.-monochloroacetoacetic acid monomethylamide; and partially recycling the mother liquor back into the chlorination process. .alpha.-Chloroacetoacetic acid monomethylamide is a valuable intermediate for producing insecticidal active compounds, for example dimethyl-1-methyl-2-(methylcarbamoyl)-vinyl phosphate.
    Type: Grant
    Filed: November 22, 1978
    Date of Patent: November 25, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Roland Dousse, Ernst Kagi