The Part Of The Chain Between The Ether Oxygen And Amino Nitrogen Consists Of Two Unsubstituted Saturated Carbons Patents (Class 564/354)
  • Patent number: 4337061
    Abstract: Novel compounds of the general formula ##STR1## wherein Z represents a substituted lower alkyl radical; each of R.sub.1 and R.sub.2 is hydrogen atom, a lower alkyl or a substituted lower alkyl identical with or different from Z and the functional groups NO.sub.2 and NR.sub.1 R.sub.2 can occupy all ring positions in relation to OZ, with the exception that if Z is .beta.-hydroxyethyl, --NO.sub.2 is in the 4 position and --N(R.sub.1)(R.sub.2) is in the 2 position then either R.sub.1 or R.sub.2 is other than hydrogen.The novel compounds are for dyeing human hair in a variety of yellow shades. The compounds of formula (I) may be used as aqueous or water-alcohol solutions to form dye compositions for dyeing human hair.
    Type: Grant
    Filed: May 3, 1976
    Date of Patent: June 29, 1982
    Assignee: Societe Anonyme dite: L'OREAL
    Inventors: Andree Bugaut, Patrick Andrillon
  • Patent number: 4336396
    Abstract: This invention relates to a process for the preparation of 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-phenol esters (I) and their salts with organic and inorganic acids comprising the reaction of thymol with a salt of an 1-halo-dimethylaminoethane to obtain ethylamine-N,N-dimethyl-2-(thymyloxy) (II), the subsequent reaction of (II) with an acylating agent according to the Friedel and Kraft reaction to obtain 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-1-acyl-benzene (III) and the oxidation of (III) to obtain the products (I) which, if desired, may be transformed in their salts with organic or inorganic acids.This process allows to obtain the products (I) in high quality and quantity without isolating any intermediate product.
    Type: Grant
    Filed: December 4, 1980
    Date of Patent: June 22, 1982
    Assignee: Blasinachim S.p.A.
    Inventors: Claudio Giordano, Aldo Belli
  • Patent number: 4333730
    Abstract: Novel meta-phenylenediamines are provided for use as couplers with dye bases in hair dye compositions. These meta-phenylenediamines have the formula: ##STR1## in which n is 2, 3 or 4. Their acid addition salts may also be used.
    Type: Grant
    Filed: April 18, 1980
    Date of Patent: June 8, 1982
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Andree Bugaut, Majdi M. Shahin, Jean-Jacques H. Vandenbossche, Gregoire Kalopissis
  • Patent number: 4311478
    Abstract: Dye, especially for human hair that consists of the new chemical compounds of the general formula ##STR1## in which Z is selected in the group consisting of hydroxyalkyl, alkoxyalkyl, acylaminoalkyl, carbalkoxyaminoalkyl, mesylaminoalkyl, ureidoalkyl, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl radicals, and the salts of the corresponding acids. Among the preferred acid salts are the sulfates, hydrochlorides, phosphates and tartrates.This dye is particularly suited for use with metadiphenols, metaphenylenediamines, metaaminophenols as well as the couplers of the formula ##STR2## in which R.sub.3 and R.sub.4 are identical or different and may represent hydrogen, alkoxy, or alkyl and in which R.sub.5 is selected from the group consisting of acyl, carbalkoxy and ureido.
    Type: Grant
    Filed: December 4, 1978
    Date of Patent: January 19, 1982
    Assignee: L'Oreal
    Inventors: Andree Bugaut, Alain R. Genet, Koovi G. Dossou
  • Patent number: 4291060
    Abstract: Novel compounds derived from formylphenoxyacetic acid such as N,N-dihexadecyl-4-(aminomethyl)phenoxy acetamide and N,N-dihexacecyl-2-(4-(aminomethyl)phenoxy) ethylamine and their non-toxic acid addition salts are useful for combating viral infections in vertebrate animals.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: September 22, 1981
    Assignee: Pfizer Inc.
    Inventor: Allen R. Kraska
  • Patent number: 4283434
    Abstract: Sulfamo dihydrochalcones of the formula ##STR1## are disclosed wherein M.sup.+ is a physiologically acceptable cation, X is H or OH, and R is a lower alkyl. These materials are useful as sweeteners for edibles. They may be prepared by sulfonating the corresponding amino dihydrochalcone using, for example, catechol sulfate.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: August 11, 1981
    Inventors: Grant E. DuBois, Rebecca A. G. Stephenson
  • Patent number: 4272550
    Abstract: Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto having antihypertensive activity are preparable by reaction of the appropriate 2,3,6-substituted-4-(polyfluoro-2-hydroxy-2-propyl)phenol or thiophenol with an alkyl ester of a bromoalkanoic acid, followed by hydrolysis to the free acid.
    Type: Grant
    Filed: October 31, 1979
    Date of Patent: June 9, 1981
    Assignee: Schering Corporation
    Inventors: Bernard R. Neustadt, Elijah H. Gold
  • Patent number: 4257980
    Abstract: The present invention provides novel 2-decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: March 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4257983
    Abstract: The present invention provides novel 2-decarboxy-2-aminomethyl-19,20-didehydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: March 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4257979
    Abstract: The present invention provides novel 2-decarboxy-2-aminomethyl-19-hydroxy-19-methyl-PG compounds and methods for their preparation and pharmacological uses for the induction of prostaglandin-like effects.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: March 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih