The Six-membered Rings Are Fused To Each Other (e.g., A-nor-progesterone, Etc.) Patents (Class 568/371)
  • SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF
    Publication number: 20140275572
    Abstract: The present invention relates to the synthesis of ent-progesterone and intermediates thereof.
    Type: Application
    Filed: March 15, 2014
    Publication date: September 18, 2014
    Inventors: John W. Cran, Yinglin Han, Faliang Zhang
  • Compositions and methods comprising magnetic resonance contrast agents
    Patent number: 8580231
    Abstract: The present invention relates to compositions and methods for imaging with magnetic resonance contrast agents. In particular, the present invention provides targeted contrast agents for selective imaging.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: November 12, 2013
    Assignee: Northwestern University
    Inventors: Preeti A. Sukerkar, Jiyoun Lee, Teresa K. Woodruff, Thomas J. Meade
  • Steroid derivatives and use thereof as medicaments
    Patent number: 7186756
    Abstract: Steroids of the formula wherein R is defined as in the application capable of increasing the synthesis of collagen.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: March 6, 2007
    Assignee: Inovat
    Inventors: Gilles Gutierrez, Mostafa Serrar, Zohra Hadid
  • Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
    Patent number: 7138520
    Abstract: In part, the present invention is directed to coordination complexes comprising a therapeutic agent. In one aspect, the subject compositions comprise a platinum metal center and a covalently attached therapeutic agent.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: November 21, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen J. Lippard, Carmen M. Barnes, Ariel Haskel, Katie R. Barnes
  • Preparation of benzoquinones by oxidation of phenols
    Patent number: 5712416
    Abstract: Process for preparing benzoquinones by oxidation of phenols in the presence of a diluent and of an oxygen-transferring catalyst which contains a heavy metal ion bound in a complex, wherein oxygen, hydrogen peroxide, a compound which liberates hydrogen peroxide, an organic hydroperoxide, a percarboxylic acid or peroxomonosulfuric acid or salts thereof are used as oxidizing agent, and wherein the oxygen-transferring catalyst is from the class of iron, manganese or chromium tetraaza?14!annulenes.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: January 27, 1998
    Assignee: BASF Aktiengesellschaft
    Inventor: Thomas Gessner
  • Synthesis of steroids
    Patent number: 4219489
    Abstract: Method and compounds are provided for use in the synthesis of steroids wherein a polyolefin is provided having an initiating group having a chalcogen atom in juxtaposition to a double bond, so as to be capable of bond formation to close to form a ring and having a terminating group involving pi unsaturation (a double or triple bond) conjugated to an aromatic ring. Upon acid catalysis, sigma bonds are formed through the interaction of a carbocation formed at the carbon atom bonded to the chalcogen atom and the double bond intermediate the initiating group and the terminating group, which close to form rings of a steroid nucleus, the carbocation interacting with the pi unsaturation conjugated with the aromatic group and being captured by a nucleophile present in the acidic reaction medium. The resulting steroid product may then be modified in known ways to produce known steroids.
    Type: Grant
    Filed: September 5, 1978
    Date of Patent: August 26, 1980
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: William S. Johnson, Leonard A. Bunes