Polyoxy Patents (Class 568/662)
  • Patent number: 9440944
    Abstract: A process for making a cyclic compounds such as cyclic acetal or cyclic ketones by feeding aldehyde or ketone compounds and polyhydroxyl compounds to a reaction zone at a molar ratio of polyhydroxyl compounds to aldehyde or ketone compounds of at least 3:1, reacting these compounds in the presence of a solid acid such as an acidic ion exchange resin, to generate a liquid reaction mixture without separating water from the reaction mixture as it is being formed in the reaction mixture, withdrawing the liquid reaction mixture from the reaction zone as a liquid product stream, and feeding the liquid reaction product stream to a distillation column to separate cyclic acetal compounds from unreacted polyhydroxyl compounds, and optionally recycling back the unreacted polyhydroxyl compounds to the reaction zone. The process produces cyclic acetal compounds in yields of at least 90% with long catalyst life. The process is also suitable to make cyclic ketals from ketone compounds.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: September 13, 2016
    Assignee: Eastman Chemical Company
    Inventors: Daniel Latham Terrill, Brian David McMurray, Damon Ray Billodeaux, James Lon Little, Adam Scott Howard
  • Patent number: 9394271
    Abstract: A liquid composition containing at least 2 mole % of water, at least 50 mole % of polyhydroxyl compounds, at least 3 mole % of cyclic compounds, and at least 0.01 mole % of a homogeneous acid catalyst. The mole percentages are based on the moles of all liquids in the composition. The liquid composition optionally contains up to 20 mole % of carbonyl compounds, based on the number of moles of the cyclic compounds. The cumulative amount of any other liquid ingredient in the liquid composition does not exceed 10 mole %. The cyclic compounds include cyclic acetals, cyclic ketals, or a combination thereof.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: July 19, 2016
    Assignee: Eastman Chemical Company
    Inventors: Daniel Latham Terrill, Brian David McMurray, Damon Ray Billodeaux, James Lon Little, Adam Scott Howard
  • Publication number: 20150011799
    Abstract: An object of the present invention is to provide a method for producing an ether compound easily in a small number of steps at lower costs in high yields. The present invention relates to a method in which the ether compound represented by the general formula (1) is produced by reacting the specific carbonyl compound specified in the general formula (2) and the specific dialkoxy compound specified in the general formula (3) with hydrogen in the presence of a hydrogenation catalyst and an acidic substance to perform hydrogenation.
    Type: Application
    Filed: February 5, 2013
    Publication date: January 8, 2015
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro Komatsuki, Kenya Ishida, Kenji Yagi
  • Publication number: 20140303271
    Abstract: The invention provides pentabromobenzyl moiety containing hydroxy-functional compounds which are useful as flame-retardants in flexible and rigid polyurethane foams and also in rigid polyisocyanurate foams. Processes for preparing the compounds, polyurethane and polyisocyanurate foams containing the compounds are also provided by the invention.
    Type: Application
    Filed: April 8, 2014
    Publication date: October 9, 2014
    Applicant: BROMINE COMPOUNDS LTD.
    Inventors: Mark GELMONT, Michael YUZEFOVICH, Dorit PELED, Orly COHEN, Ron FRIM
  • Patent number: 8829229
    Abstract: New polyol ether compounds and a process for their preparation. The process comprises reacting a polyol, a carbonyl compound, and hydrogen in the presence of hydrogenation catalyst, to provide the polyol ether. The molar ratio of polyol to carbonyl compound in the process is greater than 5:1.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: September 9, 2014
    Assignee: Dow Global Technologies LLC
    Inventors: Michael L. Tulchinsky, John R. Briggs, Cynthia L. Rand
  • Patent number: 8618337
    Abstract: The invention relates to a process for preparing polyether alcohols by reacting a) aromatic amines with b) alkylene oxides in the presence of c) a catalyst, wherein the alkylene oxide b) comprises at least 90% by weight, based on the weight of the component b), of propylene oxide and an amine is used as catalyst c).
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: December 31, 2013
    Assignee: BASF SE
    Inventors: Sirus Zarbakhsh, Markus Schuette, Marc Fricke
  • Publication number: 20130281742
    Abstract: A new methodology for the synthesis of a novel difunctional- and a known trifunctional initiator, i.e., 1,3-di(2-methoxy-2-propyl)-5-isopropyl benzene and 1,3,5-tri(2-methoxy-2-propyl)benzene, respectively, for the preparation of di- and tri-telechelic polyisobutylenes. The synthesis proceeds in three steps: 1) catalytic peroxidation of 1,3,5-triisopropylbenzene, 2) reduction of the peroxides to the corresponding alcohols, and 3) methylation of the alcohols. By controlling the conversion of the key peroxidation step the relative ratio of di- and tri-functional intermediates can be controlled. By the use of the 1,3-di(2-methoxy-2-propyl)-5-isopropyl-benzene, well-defined di-methoxy telechelic polyisobutylenes can be synthesized. Although the overall combined yield of the two initiators was only 14-20%, because of the low cost of the starting material, reagents used, and simple manipulations these compounds represent the most cost effective initiators to-date for the preparation of telechelic polyisobutylenes.
    Type: Application
    Filed: December 30, 2011
    Publication date: October 24, 2013
    Applicant: The University of Akron
    Inventors: Joseph P. Kennedy, Gabor Erdodi
  • Publication number: 20130267588
    Abstract: The invention relates to hydroxytyrosol ethers derived from fatty alcohols and phenolic compounds of olive oil and the salts, solvates and hydrates thereof, which have an affinity for type 1 cannabinoid receptors (CB1) and which can: prevent the oxidation of low-density lipoprotein (LDL); and modulate the actions regulated by said receptor, such as inducing satiety, controlling intake and reducing body fat.
    Type: Application
    Filed: December 19, 2011
    Publication date: October 10, 2013
    Applicants: FUNDACIO IMIM, FUNDACION INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Rafael De La Torre Fornell, Magin Farre Albaladejo, Maria Isabel Covas Planells, Montserrat Fito Colomer, Bruno Almeida Cotrim, Fernando Rodriguez De Fonseca, Juan Manuel Decara Del Olmo, Miguel Romero Cuevas, Jesus Joglar Tamargo, Pedro Clapes Saborit
  • Publication number: 20130190525
    Abstract: According to some aspects, the present disclosure pertains to methods of forming dimethyl 5-tert-butylisophthalate which comprise comprising converting 5-tert-butylisophthalic acid into dimethyl 5-tert-butylisophthalate in synthesis procedures that comprises methanol and a dehydrating agent as chemical reagents. In other aspects, the present disclosure pertains to methods of forming 5-tert-butyl-1,3-bis(1-methoxy-1-methylethyl)benzene that comprise deprotonating 5-tert-butyl-1,3-bis(1-hydroxy-1-methylethyl)benzene with a Brønsted-Lowry superbase and methylating the deprotonated 5-tert-butyl-1,3-bis(1-hydroxy-1-methylethyl)benzene to form the 5-tert-butyl-1,3-bis(1-methoxy-1-methylethyl)benzene.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 25, 2013
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Boston Scientific Scimed, Inc.
  • Patent number: 8466326
    Abstract: Disclosed are a production method for a ubiquinone powder for use in preparations, including Step 1 of compression molding a ubiquinone crystal powder at a linear molding pressure of from 0.6 to 2.5 tons/cm to obtain a compressed fragment; and Step 2 of grinding the compressed fragment obtained in Step 1 to obtain a powder; and a ubiquinone powder for use in preparations, which is obtained by the subject production method. According to the subject production method, it becomes possible to provide a ubiquinone powder for use in preparations for medicines and health foods, which has a high bulk density, a small angle of repose and excellent handling properties and fluidity, without using an additive such as an excipient, a binder and the like.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: June 18, 2013
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Takafumi Yoshimura, Rieko Nakano, Masayuki Furutani, Takeshi Uchiho
  • Publication number: 20130036660
    Abstract: The present invention provides methods, reactor systems, and catalysts for converting in a continuous process biomass to fuels and chemicals. The invention includes methods of converting the water insoluble components of biomass, such as hemicellulose, cellulose and lignin, to volatile C2+O1-2 oxygenates, such as alcohols, ketones, cyclic ethers, esters, carboxylic acids, aldehydes, and mixtures thereof. In certain applications, the volatile C2+O1-2 oxygenates can be collected and used as a final chemical product, or used in downstream processes to produce liquid fuels, chemicals and other products.
    Type: Application
    Filed: May 23, 2012
    Publication date: February 14, 2013
    Applicant: Virent, Inc.
    Inventors: Elizabeth Woods, Ming Qiao, Paul Myren, Randy D. Cortright, John Kania
  • Publication number: 20120317874
    Abstract: The present invention provides a nitrogen-free fuel detergent additive, fuel additive compositions containing the same, and fuel compositions containing the same, for use in internal combustion engines, where the additive is the reaction product of (i) hydrocarbyl phenol, cresol or similar material and (ii) a aldehyde, in the presence of an optional catalyst, wherein the additive provides acceptable engine deposit control that is comparable and/or better than the deposit control provided by nitrogen-containing fuel additives.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 20, 2012
    Applicant: THE LUBRIZOL CORPORATION
    Inventors: Paul R. Stevenson, David J. Moreton, Jonathan S. Vilardo, Seth Crawley, James C. Ray, Kurt F. Wollenberg
  • Patent number: 8314271
    Abstract: A method for producing certain 2-alkoxy-ethanol derivatives by depolymerising oligomeric or polymeric polyglycol derivatives in the presence of alcoholate or 1,3-diketonate derivatives of zirconium, titanium, aluminum or molybdenum.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: November 20, 2012
    Assignee: Firmenich SA
    Inventor: Denis Jacoby
  • Publication number: 20120130133
    Abstract: Processes for preparing vitamin D2 derivatives and intermediates to vitamin D2 derivatives are disclosed. An improved photolysis process for the preparation of cis intermediate (I) from the trans starting material (II) are disclosed. Also disclosed is an improved process for the formation of a trans double bond at C22-C23 of the vitamin D2 derivative, which provides high selectivity of the desired trans double bond of compound (III) over the undesired cis double bond of compound (IIIA).
    Type: Application
    Filed: November 25, 2009
    Publication date: May 24, 2012
    Applicant: CYTOCHROMA INC.
    Inventor: Uttam Saha
  • Publication number: 20110079753
    Abstract: The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of the nematic phase, a small viscosity, a suitable optical anisotropy, a suitable dielectric anisotropy and an excellent compatibility with other liquid crystal compounds. The invention also provides a liquid crystal composition containing this liquid crystal compound and a liquid crystal display device containing this liquid crystal composition. The compound is represented by formula (a). Ra is, for example, alkyl having 1 to 10 carbons, and Rb is, for example, alkenyl having 2 to 10 carbons; La is, for example, hydrogen; and Z1, Z2 and Z3 are, for example, a single bond. The liquid crystal composition comprises this compound. The liquid crystal display device comprises this liquid crystal composition.
    Type: Application
    Filed: May 21, 2009
    Publication date: April 7, 2011
    Inventors: Takahiro Kubo, Teru Shimada
  • Publication number: 20110034355
    Abstract: A composition is disclosed which comprises an aryl perfluoropolyether, optionally a halogenated oil, and further optionally a thickening agent. The composition can be used as a lubricant itself or as an additive to an oil or grease lubricant and can withstand temperatures higher than 300° C. without decomposition. The halogenated oil can be a perfluoropolyether, a fluorosilicone, a polytrifluorochloroethylene, or combinations of two or more thereof. The thickening agent can be finely divided silica, boron nitride, clay, soap, poly(tetrafluoroethylene), clay, talc, silica, titanium dioxide, polydimethylsiloxane, polyurea, polyurethane, or combinations of two or more thereof.
    Type: Application
    Filed: October 20, 2010
    Publication date: February 10, 2011
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Jon Lee Howell, Alice Elizabeth Van Der Ende, Erik William Perez, Krista Lynn Laugesen
  • Publication number: 20110034356
    Abstract: A composition is disclosed which comprises an aryl perfluoropolyether, optionally a halogenated oil, and further optionally a thickening agent. The composition can be used as a lubricant itself or as an additive to an oil or grease lubricant and can withstand temperatures higher than 300° C. without decomposition. The halogenated oil can be a perfluoropolyether, a fluorosilicone, a polytrifluorochloroethylene, or combinations of two or more thereof. The thickening agent can be finely divided silica, boron nitride, clay, soap, poly(tetrafluoroethylene), clay, talc, silica, titanium dioxide, polydimethylsiloxane, polyurea, polyurethane, or combinations of two or more thereof.
    Type: Application
    Filed: October 20, 2010
    Publication date: February 10, 2011
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Jon Lee Howell, Alice Elizabeth Van Der Ende, Erik William Perez, Krista Lynn Laugesen
  • Publication number: 20100320451
    Abstract: A fused aromatic ring derivative shown by the following formula (1): wherein Ra and Rb are independently a hydrogen atom or a substituent, m and n are independently an integer of 1 to 13, and when m and n are two or more, Ras and Rbs may be independently the same or different, and L1 is a single bond or a substituted or unsubstituted divalent linking group, provided that the fused aromatic ring derivative shown by the formula (1) does not have an anthracene ring.
    Type: Application
    Filed: November 10, 2008
    Publication date: December 23, 2010
    Inventor: Masahiro Kawamura
  • Patent number: 7728082
    Abstract: A process for producing a stable polymer such as poly(hydroxystyrene) which comprises the decarboxylation of a corresponding phenolic in the presence of a non-amine basic catalyst and a polar organic solvent, followed by the polymerization thereof.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: June 1, 2010
    Assignee: DuPont Electronic Polymers L.P.
    Inventors: Keith Joseph Kunitsky, Michael Thomas Sheehan, James Ralph Sounik, Mark Elliot Wagman
  • Patent number: 7678945
    Abstract: A process for preparing derivatized poly(4-hydroxystyrene) having a novolak type structure which comprises the steps of (i) supplying a solution of methanol containing 4-hydroxyphenylmethylcarbinol, (ii) subjecting said solution to an acid catalyzed displacement reaction for a sufficient period of time and under suitable conditions of temperature and pressure to convert substantially all of said carbinol to 4-hydroxyphenylmethylcarbinol methyl ether in solution, (iii) polymerizing said ether containing solution in the presence of a suitable acid catalyst for a sufficient period of time and under suitable conditions of temperature and pressure to form a novolak type polymer.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: March 16, 2010
    Assignee: Dupont Electronic Polymers L.P.
    Inventors: Michael T. Sheehan, Edward G. Zey
  • Publication number: 20100048940
    Abstract: New polyol ether compounds and a process for their preparation. The process comprises reacting a polyol, a carbonyl compound, and hydrogen in the presence of hydrogenation catalyst, to provide the polyol ether. The molar ratio of polyol to carbonyl compound in the process is greater than 5:1.
    Type: Application
    Filed: August 19, 2009
    Publication date: February 25, 2010
    Inventors: Michael L. Tulchinsky, John R. Briggs, Cynthia L. Rand
  • Patent number: 7638657
    Abstract: 3-[5?-(3,4-bis(hydroxymethyl)benzyloxy)-2?-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol is prepared from the novel intermediate, 6-ethyl-4?-(1-ethyl-1-hydroxypropyl)-2?-propylbiphenyl-3-ol.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: December 29, 2009
    Assignee: Galderma Research & Development
    Inventors: Eric Terranova, Sebastien Daver, Christine Marty, Jean-Claude Pascal
  • Publication number: 20090311554
    Abstract: Provided are a carbon nanotube dispersing agent, a carbon nanotube composite, a carbon nanotube film, and a method for manufacturing the carbon nanotube film. The carbon nanotube dispersing agent has at least one chromophore including at least one aromatic carbon ring, and has a plane structure.
    Type: Application
    Filed: January 4, 2008
    Publication date: December 17, 2009
    Inventors: Sang Keun Oh, Kyoung-Hwa Song, Da Jeong Jeong
  • Patent number: 7605286
    Abstract: The present invention relates to a method of protecting a hydroxyl group, which includes reacting a hydroxyl group-containing compound with a compound represented by the formula (I): wherein R is a phenyl group optionally having substituent(s), an alkyl group optionally having substituent(s) or a benzyl group optionally having substituent(s), and X is a halogen atom, in the presence of an acid catalyst to substitute the hydrogen atom of the hydroxyl group of the hydroxyl group-containing compound with a protecting group represented by the formula (II): wherein R is as defined above. The present invention provides a method capable of introducing an acetal type protecting group into a hydroxyl group under mild conditions, and a protecting reagent therefor and a method of producing the protecting reagent.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: October 20, 2009
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Tetsuya Ikemoto, Yosuke Watanabe
  • Publication number: 20090215978
    Abstract: A process for the alkoxyalkylation of an unsubstituted aromatic substrate or a substituted aromatic substrate, said substitution being via a carbon-carbon bond, said process comprising reacting the aromatic substrate with a dialkoxyalkane in the presence of a catalyst.
    Type: Application
    Filed: February 21, 2006
    Publication date: August 27, 2009
    Applicant: Davy Process Technology Limited
    Inventors: Simon Darby Roberts, Stephan William Colley
  • Patent number: 7524993
    Abstract: The present invention provides a method for obtaining reduced coenzyme Q10 which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. suited for a commercial scale production in high quality and efficiently. The high-quality oily reduced coenzyme Q10 which has low viscosity and thereby easily handled may be produced by separating an aqueous phase from the reaction mixture obtainable by oily reacting oxidized coenzyme Q10 with a reducing agent in water, or by distilling off an coexisting organic solvent at or above the melting temperature of reduced coenzyme Q10 in concentrating the organic phase containing reduced coenzyme Q10. Moreover, a solution or slurry of reduced coenzyme Q10 may be obtained by adding a desired solvent to the obtained oily product, or a solid of reduced coenzyme Q10 may be produced by contacting the oily product with a seed crystal.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: April 28, 2009
    Assignee: Kaneka Corporation
    Inventors: Takahiro Ueda, Shiro Kitamura, Yasuyoshi Ueda
  • Patent number: 7518021
    Abstract: Aromatic vinyl ether compounds represented by Formula (1) or by Formula (2) wherein each R and R? is a hydrogen atom or a group represented by Formula (3) and wherein the remaining variables are as defined in the specification, provided that at least one pR in Formula (1) and at least one uR in Formula (2) is a Formula (3) group. These aromatic vinyl ether compounds are useful as, e.g., curing agents for cationic polymerization.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: April 14, 2009
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Takahiro Iwahama, Tatsuya Nakano
  • Publication number: 20080214874
    Abstract: A process for preparing derivatized poly(4-hydroxystyrene) having a novolak type structure which comprises the steps of (i) supplying a solution of methanol containing 4-hydroxyphenylmethylcarbinol, (ii) subjecting said solution to an acid catalyzed displacement reaction for a sufficient period of time and under suitable conditions of temperature and pressure to convert substantially all of said carbinol to 4-hydroxyphenylmethylcarbinol methyl ether in solution, (iii) polymerizing said ether containing solution in the presence of a suitable acid catalyst for a sufficient period of time and under suitable conditions of temperature and pressure to form a novolak type polymer.
    Type: Application
    Filed: April 7, 2008
    Publication date: September 4, 2008
    Inventors: Michael T. Sheehan, Edward G. Zey
  • Patent number: 7417172
    Abstract: A novel perfluoroalkyl vinyl ether compound, a process for preparing a copolymer by using the perfluoroalkyl vinyl ether compound, and an optical plastic material comprising a copolymer prepared by the process are provided. More specifically, the perfluoroalkyl vinyl ether has a particular molecular structure; the process is performed by copolymerizing the perfluoroalkyl vinyl ether compound with a common fluorinated olefin in the presence of a perfluorinated radical initiator; and the optical plastic material comprises a copolymer prepared by the process and optionally a dopant.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: August 26, 2008
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jin Taek Hwang, Do Yoon Kim, Jin Sung Choi, Boris Maximov, Victor Sergeevich Yuminov, Lev Feodorovich Sokolov
  • Patent number: 7411098
    Abstract: The present invention relates to a process for preparing tetrahydrogeranylacetone (tetrahydropseudoionone) by aldol condensation of citral with acetone and subsequent hydrogenation. The invention further relates to the use of thus obtained tetrahydro-geranylacetone for preparing phytol, isophytol, tocopherol and/or tocopherol derivatives. In addition, the invention relates to processes for preparing tocopherols and/or tocopherol derivatives.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: August 12, 2008
    Assignee: BASF SE
    Inventors: Walter Dobler, Nicolaus Bahr, Alois Kindler, Christian Miller, Axel Salden
  • Publication number: 20080188557
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.
    Type: Application
    Filed: January 8, 2008
    Publication date: August 7, 2008
    Inventors: Charles C.Y. Shih, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Publication number: 20080160344
    Abstract: A novel soluble compound which is a distyrylarylene derivative having a soluble substituent and a specific central group and having a solubility of 0.5% by weight or greater at 20° C. in an organic solvent; and an organic electroluminescence device having an organic thin film layer which has a single layer or a plurality of layers, is disposed between a cathode and an anode and has at least one layer containing the novel soluble compound. The organic thin film layer can be formed in accordance with a wet process, and the organic electroluminescence device exhibiting a great efficiency of light emission can be produced easily.
    Type: Application
    Filed: February 12, 2008
    Publication date: July 3, 2008
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Chishio Hosokawa, Masakazu Funahashi, Hidetsugu Ikeda
  • Patent number: 7358403
    Abstract: An optically active compound having an unsaturated bond at an optically active binding site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated manner; and a chiral sensor comprising the optically active compound as defined above. The chiral sensor can highly selectively recognize a specified chiral compound in high sensitivity.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: April 15, 2008
    Assignee: Japan Science and Technology Agency
    Inventors: Yoshito Tobe, Keiji Hirose
  • Publication number: 20080071084
    Abstract: Method for preparing compounds of the formula (III) by reacting compounds of the formula (II) with a) an alcoholate or b) an alcohol R1-OH and a base in the presence of a Cu-containing catalyst and of a ligand, where X1-5 are independently of one another either carbon or nitrogen, or in each case two adjacent X1R1, with i=1?6, linked by a formal double bond together O, S, NRH or Nrl. The ligands preferably employed are acyclic and/or cyclic oligo- and polyglycols, oligo- and polyamides or oligo- and polyamine glycols of the general formula (IV) k is an integer >0 and n is an integer >1; X and Y are independently of one another O, NH or NR1.
    Type: Application
    Filed: May 30, 2007
    Publication date: March 20, 2008
    Inventors: Andreas MEUDT, Bernhard J. Rausch
  • Patent number: 7335751
    Abstract: The present invention provides a compound having a formula: where R1 is selected from the group consisting of alkyl, —CH2(OC2H4)OCH3, and —(OC2H4)OCH3; n is 0-4; Olig is an oligomer having a formula: -L-O-PAGR2]q where L is a optional linker moiety selected from the group consisting of —CH2O—, —CH2OX—, —OX—, —C(O)—, —C(O)X, —NH—, —NHC(O)—, —XNHC(O)—, —NHC(O)X—, —C(O)NH—, —C(O)NHX—, and where X is alkyl1-6 or is not present, Y is N or O or is not present, and R3 is alkyl1-6; PAG is a linear or branched polyalkylene glycol moiety; R2 is an alkyl1-22 capping moiety if X is present or alkyl2-22 if X is not present; and q is a number from 1 to the maximum number of branches on PAG; and m is 1-5.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: February 26, 2008
    Assignee: Biocon Limited
    Inventors: Nnochiri N. Ekwuribe, Amy L. Odenbaugh
  • Patent number: 7312249
    Abstract: Novel biaromatic vitamin D analogues have the general formula (I): and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: December 25, 2007
    Assignee: Galderma Research & Development
    Inventors: Thibaud Biadatti, Etienne Thoreau, Johannes Voegel, Andre Jomard
  • Patent number: 7208639
    Abstract: The present invention provides a method for obtaining reduced coenzyme Q10 which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. suited for a commercial scale production in high quality and efficiently. The high-quality oily reduced coenzyme Q10 which has low viscosity and thereby easily handled may be produced by separating an aqueous phase from the reaction mixture obtainable by oily reacting oxidized coenzyme Q10 with a reducing agent in water, or by distilling off an coexisting organic solvent at or above the melting temperature of reduced coenzyme Q10 in concentrating the organic phase containing reduced coenzyme Q10. Moreover, a solution or slurry of reduced coenzyme Q10 may be obtained by adding a desired solvent to the obtained oily product, or a solid of reduced coenzyme Q10 may be produced by contacting the oily product with a seed crystal.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: April 24, 2007
    Assignee: Kaneka Corporation
    Inventors: Takahiro Ueda, Shiro Kitamura, Yasuyoshi Ueda
  • Patent number: 6943271
    Abstract: A fluorine-containing styrene monomer of the formula (2) is produced by a first, second or third process. The first process includes (a) reacting a compound of the formula (1) with a compound of the formula (3), in the presence of a metal catalyst; (b) reacting the product of the step (a) with a base; and (c) reacting the product of the step (b) with hydrogen, in the presence of a metal catalyst and a phosphine or amine, thereby producing the target styrene monomer. The second process includes reacting a compound of the formula (1) with a compound of the formula (12), in the presence of a metal catalyst, thereby producing the target styrene monomer. The third process includes reacting a compound of the formula (13) with a compound of the formula (14) or (15), in the presence of a base, thereby producing the target styrene monomer.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: September 13, 2005
    Assignee: Central Glass Company, Limited
    Inventors: Shinichi Sumida, Takashi Kume, Sunao Koga, Haruhiko Komoriya
  • Publication number: 20040254403
    Abstract: The present invention provides a method for obtaining reduced coenzyme Q10 which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. suited for a commercial scale production in high quality and efficiently.
    Type: Application
    Filed: July 2, 2004
    Publication date: December 16, 2004
    Inventors: Takahiro Ueda, Shiro Kitamura, Yasuyoshi Ueda
  • Publication number: 20040249220
    Abstract: A process for producing an optically active 2-alkoxy-1-(trifluoromethyl-substituted phenyl)ethanol derivative represented by the formula 5: 1
    Type: Application
    Filed: December 19, 2003
    Publication date: December 9, 2004
    Inventors: Akihiro Ishii, Masatomi Kanai, Yokusu Kuriyama, Manabu Yasumoto, Kenjin Inomiya, Takashi Ootsuka, Koji Ueda
  • Publication number: 20040215040
    Abstract: The present invention relates to a method of conveniently and efficiently producing reduced coenzyme Q10 having excellent qualities which is useful in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, drinks, feeds, animal drugs, cosmetics, medicines, remedies, preventive drugs, etc. This method is suitable for industrial production thereof.
    Type: Application
    Filed: June 1, 2004
    Publication date: October 28, 2004
    Inventors: Takahiro Ueda, Shiro Kitamura, Yasuyoshi Ueda
  • Publication number: 20040181099
    Abstract: According to a production process, aromatic ethers are producible by reacting phenols with an oxirane compound with use of an anion exchange resin as a catalyst. According to another production process, aromatic ethers having an alcoholic hydroxyl group are producible by a crystallization-purification step of using a solvent having a solubility parameter ranging from 7.5 to 12.5 for purification by crystallization. Further, according to still another production process, producible are aromatic ethers having an alcoholic hydroxyl group, wherein the content of a metal in the aromatic ethers is less than 100 ppm by mass, and the content of a halogen element in the aromatic ethers is less than 100 ppm by mass.
    Type: Application
    Filed: July 25, 2003
    Publication date: September 16, 2004
    Inventors: Yoshiaki Hirano, Hiroshi Yamamoto, Takafumi Kubo, Hideaki Nagano, Mitsuhiro Kitajima, Hiroko Yamaguchi
  • Publication number: 20040171698
    Abstract: Antimicrobially active 4-methyl-4-aryl-2-pentanols of the Formula 1 below, methods for the preparation of these compounds and their use as antimicrobial active compounds are described.
    Type: Application
    Filed: March 3, 2004
    Publication date: September 2, 2004
    Inventors: Gerhard Schmaus, Holger Joppe
  • Publication number: 20040147789
    Abstract: This invention provides compounds of formula: 1
    Type: Application
    Filed: December 22, 2003
    Publication date: July 29, 2004
    Applicant: RHODIA CHIMIE
    Inventor: Nicolas Roques
  • Publication number: 20040138509
    Abstract: A process of producing organic compounds, such as acetaminophen, nitroalcohols and indoles, employs a catalyst system of an oxyethylene ether and a metal containing inorganic or organic reagent. The oxyethylene ether at least partially complexes the metal of the inorganic or organic reagent. As such, the reactions may be conducted neat. The processes are environmentally friendly and operationally simple.
    Type: Application
    Filed: September 19, 2003
    Publication date: July 15, 2004
    Applicant: The Texas A&M University System
    Inventors: Apurba Bhattacharya, Gaurang L. Parmar, Vikram C. Purohit, Nitin C. Patel
  • Patent number: 6756512
    Abstract: The invention relates to a novel process for preparing 2-alkyl-3-chlorophenols.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: June 29, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Walter Hübsch, Reinhard Lantzsch, Thorsten Müh, Holger Weintritt
  • Patent number: 6753444
    Abstract: The invention relates to a process for preparing 2,3,5,6-tetrahaloxylylidene compounds of formula (I) where each Hal is independently fluorine or chlorine, and X is fluorine, chlorine, bromine, —O—R, or —O—C(═O)R, where R is hydrogen, a straight-chain or branched C1-C12-alkyl- or a C6-C14-aryl radical, by reacting 2,3,5,6-tetrahaloxylylidenediamines of formula (II) with an alkyl nitrite and/or nitrous acid in HX as a solvent.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: June 22, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhard Langer, Lars Rodefeld
  • Publication number: 20040043917
    Abstract: The use of various oxime ethers are described as fragrance chemicals, suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed. Novel compounds are also disclosed.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 4, 2004
    Inventors: Anubhav P.S. Narula, Rajamony Mahesh, Manfred Pawlak, Clint Dee Winton Brooks
  • Publication number: 20040043916
    Abstract: The use of various novel oxime ethers are described as fragrance chemicals. These chemicals are suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 4, 2004
    Inventors: Anubhav P.S. Narula, Rajamony Mahesh, Manfred Pawlak, Patrick M. Merritt, Clint Dee Winton Brooks
  • Publication number: 20040015020
    Abstract: A method of converting (Z)-1-(3,5-disubstituted phenyl)-2-(4-substituted phenyl)ethene of general formula (II) to (E)-1-(3,5-disubstituted phenyl)-2-(4-substituted phenyl)ethene of general formula (I) 1
    Type: Application
    Filed: December 5, 2002
    Publication date: January 22, 2004
    Applicant: ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED
    Inventors: Pandurang Balwant Deshpande, Senthil Kumar Udayampalayam Palanisamy, Gnanaprakasam Andrew