Abstract: Provided is a surface protectant that suppresses corrosion of a semiconductor wafer surface by a basic compound, and reduces defects in the semiconductor wafer. The semiconductor wafer surface protectant of the present invention includes a compound represented by Formula (1) below; R1O—(C3H6O2)n—H??(1) where R1 denotes a hydrogen atom, a hydrocarbon group that has from 1 to 24 carbon atoms and may have a hydroxyl group, or a group represented by R2CO, where the R2 denotes a hydrocarbon group having from 1 to 24 carbon atoms; and n indicates an average degree of polymerization of a glycerin unit shown in the parentheses, and is from 2 to 60.

Abstract: This invention relates to an improved process for the preparation of a high molecular weight polyoxyalkylene polyether polyol by the continuous addition of starter (CAOS) process. This process enables a shorter cycle time while maintaining a low viscosity in high molecular weight polyoxyalkylene polyether polyols.

Abstract: The invention relates to a two-stage method for the preparation of polyoxyalkylene polyols having low equivalent molar masses, in which the method requires no reprocessing. The invention is characterized in that, in the first stage, a polyoxyalkylene polyol precursor is provided, which contains the salts of a strong Bronsted acid, and in that, in a second stage, the polyoxyalkylene polyol precursor is further reacted with alkylene oxides under DMC catalysis.

Abstract: This invention relates to a process for preparing polyols which contain oxyalkylene units. This process comprises neutralizing a crude polyol by addition of an acid, optionally removing water, and removing the salts formed by neutralization. The crude polyol is contacted with the acid for at least 5 minutes.

Abstract: This invention relates to a semi-batch process for producing low molecular weight polyoxyalkylene polyols. These polyoxyalkylene polyols are characterized by hydroxyl numbers of from 200 to 500. In accordance with the invention, the first alkylene oxide block used to activate the DMC catalyst comprises from 50% to 100% by weight of propylene oxide and from 0% to 50% by weight of ethylene oxide; and the second alkylene oxide block comprises from 50% to 100% by weight of propylene oxide and from 0% to 50% by weight of ethylene oxide. A continuously added starter is present. Optionally, a third alkylene oxide block can be added. The addition of the second alkylene oxide block and of the third alkylene oxide block when present is completed with a space time yield of greater than or equal to 250 kg/m3/hr.

Abstract: The disclosure provides for catalytic multivariate metal organic frameworks and methods of use thereof.

Abstract: The present invention provides long chain, active polyether polyols which are characterized by a functionality of 2 to 6 and an equivalent weight of 1000 to 2200 Da. These long chain polyethers comprise the alkoxylation product of (1) a starter composition having an equivalent weight of 350 Da or less, with (2) one or more alkylene oxides, in which up to 20% of ethylene oxide may be added as a cap, in the presence of (3) at least one basic catalyst. Suitable starter compositions (1) comprise the alkoxylation product of (a) a low molecular weight polyether having a functionality of 3 and an equivalent weight of less than 350 Da, (b) at least one low molecular weight starter compound comprising glycerin, and (c) propylene oxide or a mixture of propylene oxide and ethylene oxide, in the presence of (d) at least one double metal cyanide catalyst. A process for preparing these long chain polyether polyols is also disclosed.

Abstract: An improved method for recovering a purified polyether polyol comprising the steps of providing an aqueous solution of a polyether polyol containing an alkali metal catalyst residual formed from a transesterification process, contacting the aqueous solution with a stoichiometric excess of magnesium sulfate to form a second aqueous solution, removing water from said second aqueous solution at a temperature above the melt temperature of said polyether polyol to produce a dehydrated slurry containing a molten polyether polyol phase essentially free of residual alkali metal and a precipitated solid phase comprising sulfate and/or sulfite salts of the alkali metal catalyst, magnesium hydroxide, and excess magnesium sulfate and/or sulfide, passing the dehydrated slurry of through a filtration system comprising a filtration press to separate the molten polyether polyol phase from the precipitated solid phase, wherein the filtration press is treated with a filter aid that is essentially free of transition metal oxide

Abstract: There is provided a method for producing dipropylene glycol (DPG) and/or tripropylene glycol (TPG) including: (A) reacting a raw material liquid including propylene oxide and water to obtain a reaction liquid including unreacted water, propylene glycol (PG), DPG and/or TPG, and an alcohol compound excluding PG, DPG, and TPG; (B) separating, from the reaction liquid, a first liquid containing water and the alcohol compound and a second liquid containing the PG, DPG and/or TPG and optionally the alcohol compound; (C) removing a part of the alcohol compound from the first liquid to obtain a third liquid containing water and optionally a part of the alcohol compound; (D) separating, from the second liquid, a fourth liquid containing the PG and optionally the alcohol compound, and a fifth liquid containing the DPG and/or TPG and optionally the alcohol compound; and (E) recycling a part of the third liquid to step (A).

Abstract: A process for the preparation of an ether compound is disclose, wherein the ether compound is prepared via a reaction from at least an alcohol (I) and an alcohol (II), optionally using a catalyst X, wherein alcohol (I) and alcohol (II) are forming a biphasic liquid system when mixed together; comprising at least the following steps: a) Producing an alcohol (I)/alcohol (II) emulsion by using as stabilizing species amphiphilic solid particles of nanometric dimension; optionally comprising a catalyst X; b) Proceeding to the reaction of the ether compound by setting temperature, and c) Isolating the ether compound.

Abstract: A process for glycerol etherification, including a recycle of glycerol and/or mono-ether, to produce glycerol alkyl ethers with low amount of mono-ether by reacting glycerol and olefinic hydrocarbon, and/or the corresponding aldehydes, ketones and alcohols, having 2 to 10 carbon atoms in the presence of homogeneous acid catalyst with hindered formation of olefin oligomers comprising of two essential steps: reaction step (1) neutralization and salt removal step (2).

Abstract: The invention relates to a reaction system and process for continuously preparing polymethoxy dimethyl ether (DMM3-8) by a continuous acetalization reaction between an aqueous formaldehyde solution or paraformaldehyde and methanol in the presence of a functionalized acidic ionic liquid as a catalyst. The reaction system of the invention preferably comprises a formaldehyde-concentrating unit, a vacuum-drying unit, an acetalization reaction unit, a product-separating unit and a catalyst-regenerating unit. The process of the invention uses aqueous formaldehyde solution as an initial raw material, which is concentrated in the formaldehyde-concentrating unit to a concentrated formaldehyde of 50˜80 wt. %, and vacuum-dried to paraformaldehyde, or uses paraformaldehyde as raw material directly, then obtains DMM3-8 by an acetalization reaction.

Abstract: The present disclosure relates to a method of converting glycerol into organic reaction products. The method may include mixing glycerol with a monohydric alcohol. The mixture of glycerol and monohydric alcohol is then reacted in the presence of a heterogeneous nano-structured catalyst, wherein the monohydric alcohol is present at subcritical/supercritical temperatures and pressures. This converts the glycerol into one or more reaction products, wherein the reaction products include an oxygenated organic reaction product. Ninety percent or greater of the glycerol is converted.

Abstract: A process of contacting an alkylene oxide with 2-methoxy-1-propanol (PM1) in the presence of an oligomeric Schiff base metal complex catalyst is disclosed. Further, a process involving contacting an alkylene oxide with an alkyl alcohol using an oligomeric Schiff base metal complex as a catalyst is also disclosed. Additionally, novel compositions which can be used as catalysts in processes involving the contacting of an alkyl alcohol with an alkylene oxide are also disclosed.

Abstract: A process for a continuous production of a polyetherol first involves reacting a catalyst (5) with an alcohol starter (3) or an alkoxylated precursor, to give a mixture comprising an alcoholate and water. Water is then removed from the mixture. The process further involves feeding the alcoholate into a bubble column and feeding an alkylene oxide into the bottom of a compartment of the bubble column, such that the alkylene oxide rises in the alcoholate. The alkylene oxide then reacts with the alcoholate or a secondary product from the reaction between the alcoholate and alkylene oxide, to give the polyetherol.

Abstract: A method for producing methoxypolyethylene glycols includes the steps of, in the order recited: (1) preparing a reactor by washing the reactor with water; pressurizing the reactor with nitrogen; and evacuating to completely remove water and reduce oxygen content in the reactor; (2) pressurizing the reactor with nitrogen, introducing ingredients including methanol and a catalyst comprised of sodium methoxide in methanol into the reactor, and heating the ingredients; (3) introducing ethylene oxide into the reactor at a rate of 800˜1200 kg/h and reacting the methanol and the ethylene oxide to completely react the methanol; (4) introducing additional ethylene oxide into the reactor at a rate of 8000˜12000 kg/h to continue the reaction and provide final reaction products; (5) reducing the pressure in the reactor and adjusting pH of the reaction products to a ph of 5 to 7; and (6) transferring the reaction products to a tank yard.

Abstract: Provided is a surfactant composition comprising an oligoglycerol compound of formula I, wherein R and m are as defined above. The compounds exhibit favorable surfactancy properties. Advantageously, the compounds may be prepared from renewable materials.

Abstract: The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms.

Abstract: The present disclosure relates, according to some embodiments, to compositions, apparatus, methods, and systems that may be used to produce polyols, for example, polyether polyols with a narrow range of molecular weights, with little if any unsaturated byproducts, in a sustained and/or continuous reaction, with efficient heat transfer, and/or at high production rates. For example, in some embodiments, teachings of the disclosure may be used to produce polyether polyols in a continuous loop flow process. A continuous loop flow process may be practiced such that heat is effectively transferred and/or product properties (e.g., range of molecular weights) are controllable. For example, a continuous loop flow process may use one or more continuous flow loops comprising a heat exchanger, a means to move material around each loop, inlets for catalyst, monomer, initiator or starter, and an outlet for polyol product.

Abstract: The present invention relates to an improved process for manufacturing polyether and copolyether glycols by polymerization of a reaction mixture comprising at least one tetrahydrofuran or at least one tetrahydrofuran in the presence of a particular perfluorosulfonic acid resin catalyst comprising a copolymer of tetrafluoroethylene (TFE) or chlorotrifluoroethylene (CTFE) and a monomer of the formula CF2?CF—O—CF2—CF2—SO2F.

Abstract: An improved method for recovering a purified polyether polyol comprising the steps of providing an aqueous solution of a polyether polyol containing an alkali metal catalyst residual formed from a transesterification process, contacting the aqueous solution with a stoichiometric excess of magnesium sulfate to form a second aqueous solution, removing water from said second aqueous solution at a temperature above the melt temperature of said polyether polyol to produce a dehydrated slurry containing a molten polyether polyol phase essentially free of residual alkali metal and a precipitated solid phase comprising sulfate and/or sulfite salts of the alkali metal catalyst, magnesium hydroxide, and excess magnesium sulfate and/or sulfide, passing the dehydrated slurry of through a filtration system comprising a filtration press to separate the molten polyether polyol phase from the precipitated solid phase, wherein the filtration press is treated with a filter aid that is essentially free of transition metal oxide

Abstract: New polyol ether compounds and a process for their preparation. The process comprises reacting a polyol, a carbonyl compound, and hydrogen in the presence of hydrogenation catalyst, to provide the polyol ether. The molar ratio of polyol to carbonyl compound in the process is greater than 5:1.

Abstract: The present invention relates to a process for accelerated preparation of linear polymers of polyhydric alcohols using microwave irradiation as the heat element in the presence of specified catalysts.

Abstract: The present invention relates to a process for solvent-free preparation of polyether polyols with blockwise polyether chain structure, based on starter compounds solid at room temperature.

Abstract: The present invention relates to a process for preparing polyether polyols by base-catalyzed addition of alkylene oxides (epoxides) onto starter compounds which are solid at room temperature and have Zerevitinov-active hydrogen atoms, a particular feature of which is that visually clear and/or homogeneous products are obtained even in the absence of solvents.

Abstract: A new class of polyols derived from renewable resources, including polyglycerol and vegetable oils, the use of such polyols in polyurethane foams and cast resins, and methods for making the polyols and polyurethanes are provided.

Abstract: A method for producing methoxypolyethylene glycols includes the following steps: (1) after the reactor is washed by water, nitrogen is filled in the reactor to elevate the pressure and then the reactor is vacuumized to completely remove water and reduce the oxygen content in the reactor; (2) nitrogen is filled in the rector and pressure is elevated, and then methanol and sodium methoxide as the catalyst in methanol is added into the reactor, and then warming up; (3) ethylene oxide is added into the reactor at 800˜1200 kg/h to process the pre-reaction; (4) ethylene oxide is added into the reactor at 8000˜12000 kg/h to process the reaction after methanol and ethylene oxide in the reactor are completely reacted; (5) the pressure of reaction product is reduced and pH of reaction product is adjusted to 5˜7 after the reaction is finished, and then the reaction product is transferred to the tank yard.

Abstract: A polyglycerine initiated polyether polyol exhibiting a final functionality less than the nominal functionalities of the polyol initiator wherein the initiator is a polyglycerine formed by the polymerization of glycerin having an HEW less than about 35 and exhibiting a nominal functionality between 2 and 16 is provided. Also provided is a process for producing a polyfunctional polyurethane by the reaction of a mixture containing a polyol based on polyglycerine initiator wherein between 5 wt % and 100 wt % of the total initiator is polyglycerine having a nominal functionality between 2 and 16, at least one organic isocyanate, an amine and/or a metal salt catalyst, and optionally a blowing agent. Also provided is a flexible polyurethane foam comprising a reaction product of a polyglycerine or formed by the glycidol polymerization of glycerin, at least one organic isocyanate, and an amine catalyst.

Abstract: The monofunctional branched poly(ethylene glycol) (PEG) has a general formula shown in formula (1), and the bio-related substance modified by the monofunctional branched PEG has a general fomula shown in formula (2), wherein X1 and X2 are each independently a hydrocarbon group having 1 to 20 carbon atoms, n1 and n2 are each independently an integer selected from 1 to 1000, n3 is an integer selected from 11 to 1000, L1, L2 are each independently a linking group, p is 0 or 1, q is 0 or 1, R1 is a hydrogen atom or a hydrocarbon group having 1 to 20 carbon atoms, D is a bio-related substance, Z is a linking group, and Z can react with the bio-related substance to form a residue group L3. The PEG-modified bio-related substance maintains good biological activity, and has better solubility and a longer half-life in vivo.

Abstract: The present discovery uses monomers which contain reversible photo-crosslinkable groups in addition to primary polymerizable groups. The mechanical properties of these materials and the reversibility of the photo-activated shape memory effect demonstrate the effectiveness of using photo-irradiation to effect change in modulus and shape memory effect. In the preferred embodiment the reaction mixture includes a photo-reactive monomer comprising a photo reactive group and a polymerizable group; a second monomer, which is more preferably a mixture of monomers, which are acrylate based; a multi-functional crosslinking agent, preferably 1,6 hexanediol diacrylate (HDODA); an initiator, preferably a free radical initiator; and a fifth, optional, component which is a modifying polymer. The mixture of the second monomer, crosslinking agent, and initiator comprise the base polymer matrix into which the photo-reactive monomer is incorporated.

Abstract: Comb polymers having carboxyl/carboxylate and ester groups, containing a) 0.1-0.9 mol fractions of a partial structural unit S1, which is derived from an acrylic/methacrylic or maleic acid unit, b) 0-0.4 mol fractions of a partial structural unit S2, which is derived, for example, from an acrylic/methacrylic or maleic acid unit, which is esterified by means of a C1 to C20-alkanol or a polyalkylene glycol, alkyl-capped on one end, preferably a polyethylene glycol, and c) 0.1-0.4 mol fractions of a partial structural unit S3, which is derived from an acrylic/methacrylic or maleic acid unit, which is esterified by means of a polyalkylene glycol monoalkyl ether, which has a terminal, secondary hydroxyl group of the form-CH(R3)OH, wherein R3 is bulky alkyl group, preferably a methyl group.

Abstract: The present invention relates to a thermo-responsive draw solute that can be applied to water desalination and purification based on forward osmosis. The thermo-responsive draw solute has a molar mass of 50 to 3000 g/mol and undergoes a phase transition at a temperature of 0° C. to 70° C. The thermo-responsive draw solute creates optimum conditions for the desalination of seawater and the purification of contaminated water based on forward osmosis. The present invention also relates to a method for water desalination and purification using the thermo-responsive draw solute. The method consumes little energy for water desalination or purification, is simple to apply to water desalination or purification, and enables separation of the draw solute in a very easy manner.

Abstract: A multi-purpose lubricant is described. In accordance with one implementation, a lubricant comprises food grade based oils substantially complying with USDA H-1 specifications for incidental contact with food, wherein at least one oil is selected from the group consisting of food grade plant oil, food grade poly-alpha-olefin, polyalkylene glycol, and mixtures thereof. In accordance with another implementation, a lubricant comprises canola oil, castor oil and a poly-alpha-olefin. In accordance with yet another implementation, a lubricant comprises canola oil, castor oil and a polyalkylene glycol. In accordance with yet another implementation, a lubricant comprises an oil substantially complying with USDA H-2 specification wherein the oil is at least one item selected from the group consisting of plant oil, poly-alpha-olefin, polyalkylene glycol, and mixtures thereof. In some implementations, the multi-purpose lubricant may be applied to areas of a bicycle chain.

Abstract: Described herein are methods of reducing the deposition of organic contaminants, such as pitch and stickies, in papermaking processes.

Abstract: Alkyl ethers are produced directly from polyols or their salts in a single step reaction, or alternatively, the polyols are first converted to a ketal or acetal derivative which comprises at least one free hydroxyl moiety and one or more ketal or acetal moieties. In either embodiment, the polyol, its salt, or its ketal or acetal derivative is reacted with an alkylating agent to produce a first alkoxy polyol ether comprising one or more alkoxy moieties formed at the sites of the free hydroxyl moieties. Ethers prepared from the polyol ketal or acetal derivatives retain their ketal or acetal moieties, which may be hydrolyzed to additional free hydroxyls and reacted with alkylating agent to produce a second alkoxy polyol ether. Alkyl tosylates are preferred alkylating agents. The spent alkylating agents may also be recovered and regenerated. Recovered alkoxy polyol ethers may be used as renewable fuels, solvents and lubricants.

Abstract: The invention is directed to methods and compositions for reducing the deposition of pitches and stickies in a papermaking process. The method involves introducing an anionic glycerol-based polymer to the papermaking process. This anionic polymer prevents the pitches and stickies from depositing and agglomerating in papermaking processes.

Abstract: A process for making a poly(alkyl epoxide). The process has the step of polymerizing one or more alkyl epoxide monomers in the presence of a cationic catalyst according to the following sequences: wherein R1, R2, R3, and R4 are hydrogen or alkyl moieties that, taken together, have a total of 1 to 80 carbons; wherein any of R1, R2, R3, and R4 can be linear or branched if it is an alkyl moiety; wherein “m” is an integer from 1 to 4; and wherein “n” is an integer from 2 to 120. There is also another process for making a poly(alkyl epoxide) using an initiator. There are also poly(alkyl epoxides). There is also a lubricant composition having a first lubricant base stock of one or more poly(alkyl epoxides) and a second lubricant base stock different than the first lubricant base stock.

Abstract: A method is provided for producing bioderived dipropylene and tripropylene glycols without using propylene oxide. The method utilizes a bioderived (mono)propylene glycol as a feed, and in one embodiment performs an acid-catalyzed condensation process to convert the bioderived propylene glycol to products including at least dipropylene glycol and preferably including tripropylene glycol as well. Wholly biobased dipropylene glycol and tripropylene glycol products and derivative products made therefrom are described, with compositions of matter including the wholly biobased dipropylene glycol and tripropylene glycol or a derivative thereof and describing uses of the various wholly biobased products or of the compositions including the wholly biobased products. Biobased polypropylene glycols may be made in the same manner.

Abstract: The present disclosure relates to a method of converting glycerol into organic reaction products. The method may include mixing glycerol with a monohydric alcohol. The mixture of glycerol and monohydric alcohol is then reacted in the presence of a heterogeneous nano-structured catalyst, wherein the monohydric alcohol is present at subcritical/supercritical temperatures and pressures. This converts the glycerol into one or more reaction products, wherein the reaction products include an oxygenated organic reaction product. Ninety percent or greater of the glycerol is converted.

Abstract: A composition, which comprises a) an organic material susceptible to oxidative, thermal or light-induced degradation; and b) a compound of formula I (Formula I) (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are independently from each other H, C1-C8-alkyl, C4-C8-cycloalkyl, phenyl, C1-C4-alkoxy or halogen; n is 1, 2, 3, or 4; and when n is 1 A is —C(=0)-OR?1, —C(=0)-N(R?2)(R?3), —CN, phenyl, which is unsubstituted or substituted by one or more C1-C8-alkyl, C4-C8-alkoxy, C5-C7-cycloalkyl or halogen, —H or —S02-phenyl; when n is 2 A is —C(=0)-O—Z1—O—C(=0)-, —C(=0)-N(R?1)—Z2—N(R?2)—C(=0)- or piperazine-N,N?-biscarbonyl.

Abstract: Compositions comprising polyethylene glycol (PEG) are disclosed for the prophylaxis and/or treatment of head and neck squamous cell carcinomas (HNSCC). Methods for the prophylaxis and/or treatment of HNSCC comprising administering an effective amount of PEG are also disclosed. Also disclosed are methods and compositions for suppressing the surface expression of EGFR using PEG.

Abstract: Aspects of the present invention are directed to novel methods for making discrete polyethylene compounds selectively and specifically to a predetermined number of ethylene oxide units. Methods which can be used to build up larger dPEG compounds (a) containing a wider range of utility to make useful homo- and heterofunctional and branched species, and (b) under reaction configurations and conditions that are milder, more efficient, more diverse in terms of incorporating useful functionality, more controllable, and more versatile then any conventional method reported in the art to date. In addition, the embodiments of the invention allow for processes that allow for significantly improving the ability to purify the intermediates or final product mixtures, making these methods useful for commercial manufacturing dPEGs. Protecting groups and functional groups can be designed to make purification at large scale a practical reality.

Abstract: An additive for a marble adhesive, including R—(C6H4)—CH3OH, R—O—(CH2)2—O—(CH2)2—OH, R—O—CH2—CH(OH)—CH3, R-O-(CH2)2-OH, or a mixture thereof, where R represents hydrogen or an alkane.

Abstract: Alkoxylated alcohols and their use in formulations for hard surface cleaning Formulations, comprising at least one compound according to general formula (I) wherein the integers R1 are different or identical and selected from C3-C10-alkyl groups with at least two methyl groups per R1, YH is (AO)n—H, with AO being selected from —CH2CH2O— and CH2CH(R2)O— and being different or identical in the case of n>1 R2 being different or identical and selected from C1-C16-alkyl, branched or linear, n in the range of from 1 to 30, and the polydispersity being in the range of from 1.0 to 1.5.

Abstract: The invention provides an organic film composition comprises (A) a heat-decomposable polymer, (B) an organic solvent, and (C) an aromatic ring containing resin, with the weight reduction rate of (A) the heat-decomposable polymer from 30° C. to 250° C. being 40% or more by mass. There can be provided an organic film composition having not only a high dry etching resistance but also an excellent filling-up or flattening characteristics.

Abstract: Ink for inkjet printing is provided, comprising colorant and certain polyurethane ink additives which are derived from asymmetrically branched polyurethane additives which enhance fastness of the print towards highlighter and finger smudge without compromising jetting performance and storage stability of the ink.

Abstract: The present invention relates to a process for preparing polyetherols by catalytic ring-opening polymerization, wherein at least one nitrogen-containing cyclic precatalyst compound is used.

Abstract: Suggested are alkoxylation products of 2-isopropyl-5-methyl-hexan-1-ol in which AO stands for an ethylene oxide, propylene oxide or butylenes oxide unit or their mixtures and n denominates an integer of from 1 to 100.

Abstract: The present invention relates to is coupling process for the preparation of polyether polyols starting from highly functional starter compounds that are solid or highly viscous under reaction conditions and monofunctional starter compounds that are liquid under reaction conditions with Zerewitinoff-active hydrogen atoms.

Abstract: There is provided an analysis method including the steps of forming a layer including a calibration reagent, that can generate ions by using a DART ion source apparatus, in a predetermined area of a sample, and performing mass spectrometry on the ions generated from an area of the sample including the layer by using DART or DESI while moving the sample having the layer formed therein.