Phenols (h Of -oh May Be Replaced By A Group Ia Or Iia Light Metal) Patents (Class 568/706)
  • Patent number: 9000135
    Abstract: The present invention relates to a compound of general formula (I): in which: X is OH, NH2, NHOH or RNH, where R may be a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, Y is H, or an electron-withdrawing group, in particular selected from NO2, CF3 or a halogen, R1 and R2 are H or a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, F is a reactive functional group that can be activated by click chemistry.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: April 7, 2015
    Assignees: Centre Nationale de Recherche Scientifique, Universite de Poitiers
    Inventors: Sebastien Papot, Mickael Thomas
  • Patent number: 8927779
    Abstract: The present invention relates to a method for the hydroxylation of halogen aryl compounds carried out at a temperature lower than 200° C. in the presence of a catalytic system including a copper-based catalyst and a ligand L according to reaction scheme Formula (A), in which: R is selected from the groups having an acceptor inductive effect and the groups having a donor mesomer effect; M is selected from alkaline or alkaline-earth cations; X is a halogen atom; r is between 0 and 5; and the ligand L is selected from compounds having formula I.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: January 6, 2015
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Marc Taillefer, Anis Tlilli, Florian Monnier, Ning Xia
  • Patent number: 8546607
    Abstract: Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize unconventional phenol derivatives as cross-coupling partners. Embodiments of the invention can be used to synthesize a variety of useful organic compounds, for example the anti-inflammatory drug flurbiprofen.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: October 1, 2013
    Assignee: The Regents of the University of California
    Inventors: Neil K. Garg, Kyle W. Quasdorf, Xia Tian
  • Publication number: 20130144045
    Abstract: The present invention relates to a compound of general formula (I): in which: X is OH, NH2, NHOH or RNH, where R may be a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, Y is H, or an electron-withdrawing group, in particular selected from NO2, CF3 or a halogen, R1 and R2 are H or a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, F is a reactive functional group that can be activated by click chemistry.
    Type: Application
    Filed: May 18, 2011
    Publication date: June 6, 2013
    Applicants: UNIVERSITE DE POITIERS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Sebastien Papot, Mickael Thomas
  • Patent number: 8378044
    Abstract: Provided is a low-cost, environmentally friendly living radical polymerization catalyst having high activity. The catalyst is used for a living radical polymerization method, and contains a central element consisting of oxygen and at least one halogen atom bound to the central element. Furthermore, an alcohol compound can be used as a catalyst precursor. By polymerizing a monomer in the presence of the catalyst, a polymer having narrow molecular weight distribution can be obtained, and the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages of the catalyst such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (which do not require a post-treatment for a molded article), and the like.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: February 19, 2013
    Assignee: Kyoto University
    Inventors: Atsushi Goto, Takeshi Fukuda, Yoshinobu Tsujii
  • Publication number: 20120197047
    Abstract: Precipitations of nitrohydroxyaromatic salts out of the nitrated crude products obtained in the nitration of aromatic compounds after alkaline scrubbing, for example mononitrotoluenes, are prevented by contacting the nitrated crude products with an acidic ion exchanger. The nitrated crude products are preferably selected from a feedstream to a distillation column, a bottoms circulation stream of a distillation column and a feedstream to a vaporizer.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 2, 2012
    Applicant: BASF SE
    Inventors: Holger ALLARDT, Andreas RAICHLE, Reiner REETZ, Johannes BÜTTNER, Michael ZÖLLINGER, Stefanie HAASE, Rüdiger FRITZ
  • Publication number: 20120157704
    Abstract: The present invention relates to a method for the hydroxylation of halogen aryl compounds carried out at a temperature lower than 200° C. in the presence of a catalytic system including a copper-based catalyst and a ligand L according to reaction scheme Formula (A), in which: R is selected from the groups having an acceptor inductive effect and the groups having a donor mesomer effect; M is selected from alkaline or alkaline-earth cations; X is a halogen atom; r is between 0 and 5; and the ligand L is selected from compounds having formula I.
    Type: Application
    Filed: June 8, 2010
    Publication date: June 21, 2012
    Inventors: Marc Taillefer, Anis Tlilli, Florian Monnier, Ning Xia
  • Patent number: 8080689
    Abstract: Disclosed are compounds represented by structural formula (I): methods of producing compounds represented by structural formula (I), and their use in inhibiting oxidation in an oxidizable material.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: December 20, 2011
    Assignee: Polnox Corporation
    Inventors: Rajesh Kumar, Suizhou Yang, Vijayendra Kumar, Ashok L. Cholli
  • Publication number: 20110218364
    Abstract: An intermetallic magnetic compound of iron oxide and palladium with a nanometer particle size is disclosed, together with a method of making magnetic nanoparticles that include an intermetallic bond between palladium and iron-oxide. Additionally, a method is disclosed of catalyzing an organic reaction by contacting the organic reagents with an intermetallic magnetic compound of iron oxide and palladium that has nanometer particle size in an amount sufficient to catalyze the organic reaction.
    Type: Application
    Filed: March 5, 2010
    Publication date: September 8, 2011
    Applicant: CEM CORPORATION
    Inventors: Keith A. Porter, E. Keller Barnhardt
  • Publication number: 20110124832
    Abstract: Provided is a low-cost, environmentally friendly living radical polymerization catalyst having high activity. The catalyst is used for a living radical polymerization method, and contains a central element consisting of oxygen and at least one halogen atom bound to the central element. Furthermore, an alcohol compound can be used as a catalyst precursor. By polymerizing a monomer in the presence of the catalyst, a polymer having narrow molecular weight distribution can be obtained, and the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages of the catalyst such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (which do not require a post-treatment for a molded article), and the like.
    Type: Application
    Filed: February 6, 2009
    Publication date: May 26, 2011
    Applicant: KYOTO UNIVERSITY
    Inventors: Atsushi Goto, Takeshi Fukuda, Yoshinobu Tsujii
  • Publication number: 20110009649
    Abstract: A method for preparing 2-(n-butyl)-5-nitrobenzofuran from 1-halo-4-nitrobenzene, characterized in that 1-hexen-3-ol is reacted, and then the product is subject to a Claisen rearrangement, followed by catalytic intramolecular cyclization.
    Type: Application
    Filed: April 4, 2008
    Publication date: January 13, 2011
    Inventors: Thierry Durand, Ousmanne Diouf, Stephane Lemeune, Jean-Francois Marcoux, Vivien Henryon, Jerome Monbrun, Madeleine Delamare
  • Publication number: 20100319243
    Abstract: The present disclosure relates to a gasoline combustion improver comprising an organic nitro compound with C—NO2 bond dissociation energy of about 60 to about 80 Kcal/mol of compound, wherein the organic nitro compound is selected from the group consisting of nitro-aromatics, heteroatom aromatic ring compounds, heteroatom nonaromatic ring compounds, and nitrated furfuryls, and wherein the organic nitro compound is not nitrotoluene or dinitrotoluene.
    Type: Application
    Filed: June 22, 2009
    Publication date: December 23, 2010
    Applicant: Afton Chemical Corporation
    Inventors: Allen A. ARADI, Joseph W. Roos
  • Publication number: 20100298567
    Abstract: The invention relates to the nitration of aromatic or heteroaromatic compounds, wherein an activated aromatic or heteroaromatic compound and a nitration agent, optionally in the presence of a solvent, are mixed intensely in a microreactor, and wherein the proportion of the nitration agent to the activated aromatic or heteroaromatic compound, the concentration of nitration agent in the reaction mixture, and the temperature are selected at levels such high that the nitration begins autocatalytically, and wherein the nitration product is obtained after leaving the microreactor and, optionally after an after-reaction time outside the microreactor.
    Type: Application
    Filed: January 12, 2006
    Publication date: November 25, 2010
    Applicant: LONZA AG
    Inventors: Dominique Roberge, Laurent Ducry
  • Patent number: 7799948
    Abstract: Disclosed are compounds represented by structural formula (I): methods of producing compounds represented by structural formula (I), and their use in inhibiting oxidation in an oxidizable material.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: September 21, 2010
    Assignee: Polnox Corporation
    Inventors: Rajesh Kumar, Suizhou Yang, Vijayendra Kumar, Ashok L. Cholli
  • Patent number: 7799949
    Abstract: A compound represented by the formula below is provided. (In the formula, X and Y denote a hydroxy group, an amino group, or a halogen atom, and X and Y are groups that are different from each other.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: September 21, 2010
    Assignee: FUJIFILM Corporation
    Inventors: Youhei Kubo, Koki Nakamura, Katsuyuki Watanabe
  • Patent number: 7737308
    Abstract: Methods of nitrating compounds, such as phloroglucinol or a methoxy derivative thereof, are disclosed. For example, a reaction mixture may be formed by combining sulfuric acid and at least one nitrate salt. A nitratable aromatic compound, such as phloroglucinol or a methoxy derivative thereof, may then be exposed to the reaction mixture to nitrate the phloroglucinol or methoxy derivative thereof.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: June 15, 2010
    Assignee: Alliant Techsystems Inc.
    Inventor: Nicholas A. Straessler
  • Publication number: 20090043134
    Abstract: Selective and efficient multifunctional nanoporous catalysts containing spatially distributed organoamine and silanol groups, and methods of preparation thereof. The catalysts have been observed to be very highly efficient in catalysis of the Henry reaction.
    Type: Application
    Filed: August 8, 2008
    Publication date: February 12, 2009
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Tewodros Asefa, Krishna K. Sharma, Abhishek Anan
  • Patent number: 7256310
    Abstract: Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: August 14, 2007
    Assignee: Sepracor Inc.
    Inventors: Paul McGlynn, Roger Bakale, Craig Sturge
  • Patent number: 7005553
    Abstract: A method for the regioselective ortho-directed nitration of phenolic compounds useful for the preparation of ortho-nitro-phenols according to formula (I) is described.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: February 28, 2006
    Assignee: Portela, C.A., S.A.
    Inventor: David Alexander Learmonth
  • Publication number: 20040192961
    Abstract: A method for the regioselective ortho-directed nitration of phenolic compounds useful for the preparation of ortho-nitro-phenols according to formula (I) is described.
    Type: Application
    Filed: May 20, 2004
    Publication date: September 30, 2004
    Inventor: David Alexander Learmonth
  • Patent number: 6727393
    Abstract: A process for the preparation of a solution of a quaternary cation and an anion from a deprotonated hydroxy aromatic in an organic solvent by means of a reactive extraction of a quaternary salt in the presence of an aqueous hydroxide solution, a hydroxy aromatic and an organic solvent is disclosed. Also disclosed is a process for the recycling of a quaternary salt phenolate solution from a reaction mixture.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: April 27, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Claus-Peter Reisinger, Sven Michael Hansen, Peter Fischer, Michael Traving
  • Publication number: 20030065229
    Abstract: Disclosed are an efficient, safe process for producing artepillin C and derivatives thereof by an organic synthesis. The process comprises a step of reacting a phenol derivative with an acrylate or acrylic acid.
    Type: Application
    Filed: November 28, 2001
    Publication date: April 3, 2003
    Inventors: Hitoshi Hori, Yoshinori Nakagawa
  • Publication number: 20020176895
    Abstract: The present invention discloses the process of extraction, purification and characterization of a fluorescent dye from a marine echinoderm Holothuria scabra, compositions containing the dye and various applications of the dye.
    Type: Application
    Filed: March 30, 2001
    Publication date: November 28, 2002
    Inventors: Usha Goswami, Anutosh Ganguly
  • Publication number: 20010004674
    Abstract: A process for producing an aromatic ring alkylated phenols, wherein said process comprises reacting phenols represented by the general formula (1): 1
    Type: Application
    Filed: December 13, 2000
    Publication date: June 21, 2001
    Inventors: Tomoyuki Suzuki, Fumisato Goto, Kozo Tanaka
  • Patent number: 6242657
    Abstract: In the reaction of aromatic compounds with nitrating acids comprising HNO3 and, if appropriate, H2SO4 and/or H2O and/or H3PO4 to form aromatic nitro compounds, according to the invention an amount of from 0.5 to 20,000 ppm of one or more surface-active substances from the group of the anionic, cationic, zwitterionic or nonionic surface-active substances is added to the reaction mixture.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: June 5, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd-Michael König, Johannes Dühr, Hans-Joachim Raatz, Manfred Kaczorowski
  • Patent number: 5874654
    Abstract: Environmentally-polluting nitrocresol values are removed from admixtures of nitroaromatic compounds comprised thereof, notably the media of nitration of aromatic compounds by reacting same with aqueous HNO.sub.3 /H.sub.2 SO.sub.4, by first intimately contacting such nitroaromatic compound admixtures with an oxidizing agent comprising hydrogen peroxide, javelle water, or mixture thereof, and thereafter with a neutralizing agent; the nitroaromatic aromatic compounds thus purified are conveniently catalytically hydrogenated into aromatic amines.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: February 23, 1999
    Assignee: Rhone Poulenc Chimie
    Inventors: Antoinette Gacon-Camoz, Pascal Metivier
  • Patent number: 5872289
    Abstract: A liquid-phase process for hydrolyzing a carboxylic acid alkyl ester having 2 to 18 carbon atoms to provide a product mixture comprising a carboxylic acid and an alcohol comprising contacting a feedstock comprising the carboxylic acid alkyl ester and water with an acidic carbon catalyst under reaction conditions sufficient to form the product mixture comprising the carboxylic acid and the alcohol. Suitable acidic carbon catalysts include charcoal and carbons produced from a variety of sources including coconut shells, coal, wood and peat. Carbon catalysts may be rendered acidic by treatment with nitric acid.
    Type: Grant
    Filed: March 6, 1998
    Date of Patent: February 16, 1999
    Assignee: Air Products and Chemicals, Inc.
    Inventors: John Bruce Appleby, Francis Joseph Waller, Stephen Charles Webb
  • Patent number: 5847231
    Abstract: Process for preparing 4-nitrophenol derivatives of formula (IV) with high selectivity, which comprises converting phenols to diphenyl oxalate derivatives of formula (III) and conducting nitration reaction and hydrolysis to give said 4-nitrophenol derivatives. ##STR1## In the above formulae, R is, the same or different from each other, an alkyl group having 1 to 4 carbon atoms; a halogen atom; an alkoxy group having 1 to 4 carbon atoms; a formyl group; a nitrile group; --COOR.sup.1 (R.sup.1 is an alkyl group having 1 to 4 carbon atoms); --CONR.sup.2 R.sup.3 (R.sup.2 and R.sup.3 are, the same or different from each other, hydrogen atom(s) or alkyl group(s) having 1 to 4 carbon atoms); or --COR.sup.4 (R.sup.4 is an alkyl group having 1 to 4 carbon atoms), andR is not substituted at the 4-position of the phenyl ring and not substituted at the 2- and 6-positions of the phenyl ring at the same time, and,n is 1, 2 or 3.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: December 8, 1998
    Assignee: Junsei Chemical Co., Ltd.
    Inventors: Hideki Kanno, Hiroyuki Chida, Yurie Otani
  • Patent number: 5798443
    Abstract: The present invention relates to a reaction and dissolving medium for the synthesis of peptides. This reaction and dissolving medium for peptide synthesis and/or purification comprises a diluent A chosen from a group of water-immiscible solvents and a phenol B. This peptide synthesis can be used to synthesize medicaments, vaccines, agro-foodstuff products or plant protection products.
    Type: Grant
    Filed: March 10, 1994
    Date of Patent: August 25, 1998
    Assignee: Rhone-Poulenc Chimie
    Inventors: Marie Galvez, Marie-France Maurice
  • Patent number: 5659065
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aromatic or heteroaromatic radical, a hydroxy group that is aliphatically, araliphatically or heteroarylaliphatically etherified or protected by a hydroxy-protecting group, or an aliphatically etherified mercapto group, andR.sub.2 is an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radical, orR.sub.1 and R.sub.2 together form a divalent aliphatic radical,R.sub.3 is free or aliphatically, araliphatically or aromatically esterified carboxy, formyl or hydroxymethyl,R.sub.4 is hydrogen, an aliphatic or araliphatic radical or an amino-protecting group, andR.sub.5 is hydrogen or an aliphatic radical,and the salts thereof can be used as intermediates in the preparation of medicinal active ingredients.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: August 19, 1997
    Assignee: Novartis Corporation
    Inventor: Richard Goschke
  • Patent number: 5414148
    Abstract: p-Nitrophenolic compounds, e.g., p-nitrophenol itself, are selectively prepared by (a) reacting a phenolic compound with a nitrosating agent in the presence of sulfuric acid, the concentration of which H.sub.2 SO.sub.4 being at least 60%, (b) oxidizing the p-nitrosophenolic compound thus formed with nitric acid, the concentration of sulfuric acid in the medium of reaction, upon completion of oxidation, being no greater than 80%, and (c) separating the p-nitrophenolic compound which thus precipitates.
    Type: Grant
    Filed: May 26, 1994
    Date of Patent: May 9, 1995
    Assignee: Rhone-Poulenc Chimie
    Inventors: Pascal Metivier, Laurent Bernard
  • Patent number: 5393776
    Abstract: This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a method of use employing those compositions.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: February 28, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventor: Bradley C. Pearce
  • Patent number: 5283352
    Abstract: Catechol compounds of formula I ##STR1## where R.sub.1, R.sub.2, R.sub.3 and X are as described herein are effective Catechol-O-methyltransferase inhibitors.
    Type: Grant
    Filed: December 7, 1992
    Date of Patent: February 1, 1994
    Assignee: Orion-yhtyma Oy
    Inventors: Reijo J. Backstrom, Kalevi E. Heinola, Erkki J. Honkanen, Seppo K. Kaakkola, Pekka J. Kairisalo, Inge-Britt Y. Linden, Pekka I. Mannisto, Erkki A. O. Nissinen, Pentti Pohto, Aino K. Pippuri, Jarmo J. Pystynen
  • Patent number: 5104414
    Abstract: A 2-alkyl-4-methoxy-5-aminophenol or a salt thereof; a 2-alkyl-4-methoxy-5-nitrophenol or 2-alkyl-4-methoxy-5-nitrophenyl mesylate, each an intermediate in the preparation of the 2-alkyl-4-methoxy-5-aminophenol; and a dyeing composition for keratin fibers comprising a color-developing material and the 2-alkyl-4-methoxy-5-aminophenol or the salt thereof as a coupling agent are disclosed.Further, a 2-alkyl-4-methoxy-5-substituted aminophenol or a salt thereof; a 2-alkyl-4-methoxy-5-substituted aminophenol derivative, which is an intermediate in the preparation of the 2-alkyl-4-methoxy-5-substituted aminophenol; and a dyeing composition for keratin fibers comprising a color-developing material and the 2-alkyl-4-methoxy-5-substituted aminophenol, the salt thereof, or the 2-alkyl-4-methoxy-5-substituted aminophenol derivative as a coupling agent are disclosed.
    Type: Grant
    Filed: May 1, 1991
    Date of Patent: April 14, 1992
    Assignee: Kao Corporation
    Inventors: Tadashi Tamura, Akira Kiyomine, Yoshinori Nishizawa, Hidetoshi Tagami, Toru Yoshihara, Jiro Kawase
  • Patent number: 5030769
    Abstract: Nitrophenols, in an isomer ratio para-nitrophenol/ortho-nitrophenol of at least 55/45, are continuously and directly prepared in steady state, by (a) establishing, in a confined reaction zone, an aqueous reaction solution including from 5% to 40% by weight of nitric acid, from 5% to 40% by weight of nitrous acid relative thereto, and an amount of nitrophenols within the limits of the solubility thereof in such reaction solution, (b) continuously introducing and reacting phenol and nitric acid into and with such reaction solution, at a rate of about 0.5 to 2.0 moles of nitric acid per mole of phenol, (c) maintaining the temperature in such confined reaction zone at a value ranging from about 10.degree. to about 40.degree. C. during such reaction, and (d) continuously withdrawing from such confined reaction zone admixture of para-nitrophenol and ortho-nitrophenol, in an isomer ratio para-nitrophenol/ortho-nitrophenol of at least 55/45.
    Type: Grant
    Filed: November 7, 1989
    Date of Patent: July 9, 1991
    Assignee: Rhone-Poulenc Chimie
    Inventors: Michel Baudouin, Jean-Luc Bougeois, Serge Ratton, Jean-Pierre Lecouve
  • Patent number: 5021580
    Abstract: Polybenzoxazole polymers can be synthesized from BB-monomer having pendant methyl groups. The resulting polymer has pendant methyl groups, which can be used to cross-link the polymers.
    Type: Grant
    Filed: October 23, 1989
    Date of Patent: June 4, 1991
    Assignee: The Dow Chemical Company
    Inventor: Zenon Lysenko
  • Patent number: 5019659
    Abstract: Disclosed is a method for selectively separating 2-nitrosophenol from an isomeric mixture containing 2-nitrosophenol and 4-nitrosophenol by contacting the mixture with an organic solvent so as to preferentially dissolve the 2-nitrosophenol from the mixture.
    Type: Grant
    Filed: August 17, 1990
    Date of Patent: May 28, 1991
    Assignee: PPG Industries, Inc.
    Inventors: James A. Manner, Charles H. Hoelscher
  • Patent number: 5015260
    Abstract: A 2-alkyl-4-methoxy-5-aminophenol or a salt thereof; a 2-alkyl-4-methoxy-5-nitrophenol or 2-alkyl-4-methoxy-5-nitrophenyl mesylate, each an intermediate in the preparation of the 2-alkyl-4-methoxy-5-aminophenol; and a dyeing composition for keratin fibers comprising a color-developing material and the 2-alkyl-4-methoxy-5-aminophenol or the salt thereof as a coupling agent are disclosed.Further, a 2-alkyl-4-methoxy-5-substituted aminophenol or a salt thereof; a 2-alkyl-4-methoxy-5-substituted aminophenol derivative, whcih is an intermediate in the preparation of the 2-alkyl-4-methoxy-5-substituted aminophenol; and a dyeing composition for keratin fibers comprising a color-developing material and the 2-alkyl-4-methoxy-5-substituted aminophenol or the salt thereof as a coupling agent are disclosed.
    Type: Grant
    Filed: July 27, 1990
    Date of Patent: May 14, 1991
    Assignee: Kao Corporation
    Inventors: Tadashi Tamura, Akira Kiyomine, Yoshinori Nishizawa, Hidetoshi Tagami, Toru Yoshihara, Jiro Kawase
  • Patent number: 4982001
    Abstract: High purity amino-1,3-benzenediols are prepared by (a) contacting a 1,3-bis(alkylcarbonato)benzene with a nitrating agent under reaction conditions such that a 1,3-bis(alkylcarbonato)nitrobenzene is formed, (b) contacting the 1,3-bis(alkylcarbonato)nitrobenzene with a hydrolyzing agent under conditions such that a nitro-1,3-benzenediol is produced, and (c) contacting the nitro-1,3-benzenediol with a reducing agent under conditions such that an amino-1,3-benzenediol is produced. Of the amino-1,3-benzenediols, 4,6-diamino-1,3-benzenediol is particularly useful in the preparation of high molecular weight polybenzoxazoles.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: January 1, 1991
    Assignee: The Dow Chemical Company
    Inventors: Zenon Lysenko, Cynthia L. Rand
  • Patent number: 4978808
    Abstract: Disclosed herein is a method of producing 2,2-bis(3-nitro-4-hydroxphenyl)hexafluoropropane, which comprises (a) preparing 2,2-bis(4-hydroxyphenyl)hexafluoropropane and a lower fatty acid; and (b) allowing the 2,2-bis(4-hydroxyphenyl)hexafluoropropane to react with nitric acid in the lower fatty acid.
    Type: Grant
    Filed: May 31, 1989
    Date of Patent: December 18, 1990
    Assignee: Central Glass Company, Limited
    Inventors: Masamichi Maruta, Tetsuo Wada
  • Patent number: 4975093
    Abstract: The hair dyeing composition in the form of an aqueous solution, an aqueous-alcoholic solution, a cream, a gel, a mixture which can be sprayed or an emulsion contains from 0.01 to 2.0% of a 2,6-Dinitro-phenol derivative of the formula (I): ##STR1## wherein X represents a member selected from the group consisting of alkyl groups containing one to four carbon atoms, monohydroxyalkyl groups containing one to four carbon atoms, perfluoroalkyl groups containing one to four carbon atoms, alkoxy groups containing one to four carbon atoms, monohydroxyalkoxy groups containing two to four carbon atoms, dihydroxyalkoxy groups containing three to four carbon atoms and halogens, and one or more cosmetic additives selected from the group consisting of glycerin, glycols, glycol ethers, hair car materials, wetting agents and emulsifiers, thickeners, softeners, preservatives, complexing agents and perfumes. The dyes of the formula (I) have good physiological properties and provide a variety of yellow shades.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: December 4, 1990
    Assignee: Wella Aktiengesellschaft
    Inventors: Thomas Clausen, Wolfgang Balzer, Gunther Lang
  • Patent number: 4962198
    Abstract: The invention relates to a generally applicable process for the hydroxylation of electrophilic aromatic compounds, according to which the electrophilic aromatic compounds are reacted with organic hydroperoxides in the presence of bases.
    Type: Grant
    Filed: July 7, 1989
    Date of Patent: October 9, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Mieczyslaw Makosza, Krzysztof Sienkiewicz
  • Patent number: 4960955
    Abstract: The process of making 4-chloro-2-methyl-5-nitro phenol (I) ##STR1## comprises nitrating a 4-chloro-2-methyl-phenyl sulfonate of the formula (II) at the 5 position ##STR2## in which R is a residue selected from the group consisting of methyl-, ethyl-, trifluoromethyl-, phenyl- and tolyl and the sulfonyl residue comprises --SO.sub.2 R at the position 5 to form 4-chloro-2-methyl-5-nitro-phenyl-sulfonate and then cleaving the sulfonyl residue of the 4-chloro-2-methyl-5-nitro-phenyl-sulfonate to form the 4-chloro-2-methyl-5-nitro-phenyl. The process uses technically available and economical starting materials and allows an isomerically pure product to be made in very good yield.
    Type: Grant
    Filed: May 17, 1989
    Date of Patent: October 2, 1990
    Assignee: Wella Aktiengesellschaft
    Inventors: Thomas Clausen, David Rose
  • Patent number: 4954653
    Abstract: The invention discloses a catalyst on the basis of silicon and titanium having the form of microspheres and constituted by oligomeric silica and by titanium-silica-lite crystals having an oligomeric silica/titanium-silicalite molar ratio comprised within the range of from 0.05 to 0.11, wherein the crystals of titanium-silicalite are encaged by means of Si-O-Si bridges.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: September 4, 1990
    Assignee: Enichem Sintesi S.p.A.
    Inventors: Giuseppe Bellussi, Franco Buonomo, Antonio Esposito, Mario Clerici, Ugo Romano, Bruno Notari
  • Patent number: 4912246
    Abstract: High purity amino-1,3-benzenediols are prepared by (a) contacting a 1,3-bis(alkylcarbonato)benzene with a nitrating agent under rection conditions such that a 1,3-bis(alkylcarbonato)nitrobenzene is formed, (b) contacting the 1,3-bis(alkylcarbonato)nitrobenzene with a hydrolyzing agent under conditions such that a nitro-1,3-benzenediol is produced, and (c) contacting the nitro-1,3-benzenediol with a reducing agent under conditions such that an amino-1,3-benzenediol is produced. Of the amino-1,3-benzenediols, 4,6-diamino-1,3-benzenediol is particularly useful in the preparation of high molecular weight polybenzoxazoles.
    Type: Grant
    Filed: October 19, 1987
    Date of Patent: March 27, 1990
    Assignee: The Dow Chemical Company
    Inventors: Zenon Lysenko, Cynthia L. Rand
  • Patent number: 4835324
    Abstract: A compound of the formula: ##STR1## wherein R is NH.sub.2 or NO.sub.2, and X is chlorine or bromine, is disclosed. These compounds are useful as intermediates in the production of herbicidal tetrahydrophthalimides of the formula: ##STR2## wherein R' is a C.sub.3 -C.sub.4 alkenyl group or a C.sub.3 -C.sub.4 alkynyl group, and X is as defined above.
    Type: Grant
    Filed: December 9, 1987
    Date of Patent: May 30, 1989
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Eiki Nagano, Shunichi Hashimoto, Ryo Yoshida, Hiroshi Matsumoto, Katsuzo Kamoshita
  • Patent number: 4827047
    Abstract: The chloronitrophenols, e.g., 2,6-dichloro-4-nitrophenol (a known agrochemical/pharmaceutical intermediate), are efficiently prepared by chlorinating ortho- or para-nitrophenol with gaseous chlorine, characteristically in the molten state, and in the presence of a catalytically effective amount of a primary, secondary or tertiary amine.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: May 2, 1989
    Assignee: Rhone-Poulenc Chimie
    Inventors: Jean-Roger Desmurs, Isabelle Jouve
  • Patent number: 4814518
    Abstract: The invention relates to a process for extracting nitrohydroxyaromatics from aqueous solutions. In this process, the extracting agent used is an amine salt which comprises an aliphatic amine having a total carbon number of 10 to 75 and a strong acid. The amine salt can be employed undiluted or diluted with an organic solvent.
    Type: Grant
    Filed: August 12, 1987
    Date of Patent: March 21, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Helmut Gossel, Herbert Kuckertz, Siegbert Rittner, Josef Rosenfelder, Bernhard Wojtech
  • Patent number: 4788346
    Abstract: A process for the preparation of para-nitrophenol by bringing a phenyl ester of an inorganic acid into contact with a nitrating agent in the presence of liquid hydrofluoric acid and a hydrolysis of the nitrated product obtained is carried out either simultaneously or in sequence with the nitration.
    Type: Grant
    Filed: May 27, 1987
    Date of Patent: November 29, 1988
    Assignee: Rhone-Poulenc Chimie
    Inventor: Michel Desbois
  • Patent number: RE33168
    Abstract: The present invention relates to improvements in processes of preparing dinitrated .[.aromatic compounds, particularly dinitrated aniline and dinitrated substituted aniline compounds, employing relatively dilute and then more concentrated nitric acid as the nitrating agent.]. .Iadd.aniline and substituted phenol compounds in a two-step process, employing, in the first or mononitration step the spent nitric acid from the second of dinitration step. .Iaddend.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: February 20, 1990
    Assignee: Jerome A. Gross
    Inventor: Larry A. McDaniel