Abstract: Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a neural stimulation system that receives an indication of an ambient audio signal detected by a microphone. The system selects, from a profile, an audio signal including a fixed parameter and a variable parameter. The system sets the variable parameter to a first value. The system generates an output signal based on the fixed parameter and the first value, and provides the output signal to the speaker. The system measures a physiological condition of the subject, adjusts the variable parameter to a second value, generates a second output signal based on the fixed parameter and the second value of the variable parameter, and provides the output signal to the speaker to cause the speaker to provide modified sound to the subject.

Abstract: Various improvements are provided to breathing training, monitoring and/or assistance devices. A portable device is provided which optionally includes a gas canister, a feedback system for implementing pressure control, and a visual output for indicating adherence to a breathing exercise to the user. The pressure control may provide regulation of different pressures for inhalation and exhalation.

Abstract: A system and method for health diagnostics and more specifically to an image-capture based system and method for detecting physiological state for a subject. The system provides a remote and non-invasive approach by which to detect physiological state with a high confidence. The system enables monitoring of hemoglobin concentration changes by optical imaging and related detection systems.

Abstract: Visual and auditory stimuli are provided to a patient to treat various neurological disorders or conditions and/or to provide improved mental or physical performance. The visual and auditory stimuli are provided by a wearable headset or sleep mask that may be comfortably worn by a user, such as in bed to induce sleep. The wearable headset or sleep mask includes, or works in cooperation with, sensors that determine the state of the user and modify the operation of the headset for treating various disorders or contentions.

Abstract: The present disclosure provides a system and a method for relaxation and cultivation of attention. The method comprising: detecting a non-respiratory bodily action of a first person; determining based on comparing the non-respiratory bodily action of the first person with at least one predetermined threshold, whether or not the first person is voluntarily attending on the non-respiratory bodily action at the present time; and generating feedback to be perceived by the first person through at least one response system if the first person is voluntarily attending on the non-respiratory bodily action at the present time.

Abstract: Introduced are methods and systems for an adjustable bed device configured to: gather biological signals associated with multiple users, such as heart rate, breathing rate, or temperature; analyze the gathered human biological signals; and heat or cool a bed based on the analysis.

Abstract: A method for security and/or automation systems is described. In one embodiment, the method may include receiving input regarding at least one home automation system operation profile. The method may further include receiving monitored sleep data of at least one user of a home automation system associated with the at least one home automation system operation profile. The method may further include comparing the received monitored sleep data with the received input regarding the at least one home automation system operation profile, and may include implementing the at least one home automation system operation profile based, at least in part, on the comparing.

Abstract: Methods and systems are provided to monitor bio-signals associated with one or more physiological structures of a subject, process the bio-signals to determine neural information, determine a current state of the subject based on the neural information, determine feedback to be provided to the subject based on the current neural state and a desired neural state, and/or to provide the feedback to the subject in order to modify the subject's current neural state to the desired neural state. The neural information may include validated neural indices relating to dynamic regulation of the monitored physiological structures via identifiable neural pathways and/or neural metrics quantified from such neural indices.

Abstract: A subject's forehead, and underlying pre-frontal cortex may be cooled by positioning a pre-cooled heat transfer pack on the subject's forehead so that the heat transfer pack is in thermal communication with the subject's forehead, the temperature of the pre-cooled heat transfer pack being below 10° Celsius. Thermal communication between the subject's forehead and the heat transfer pack may be maintained for a period of time sufficient to cool the subject's pre-frontal cortex. Cooling of the pre-frontal cortex may slow the metabolic rate of the subject's pre-frontal cortex and/or induce an onset of sleep for the subject.

Abstract: Systems slow breathing with positive pressure therapy. In embodiments, a current interim breathing rate target is set, and periodically magnitude of a variable pressure waveform scaled to the current interim breathing rate target is increased if breathing rate is greater than the interim rate target to lengthen breath duration. The magnitude of the pressure increase may be a function of the difference between the interim rate target and the breathing rate. The interim rate target may be reduced in response to slowing breathing rate. The waveform cycles, inhalation to exhalation, when airflow decreases to a cycle threshold. Different interim rate targets have different cycle threshold functions that allow easier cycling as the interim rate targets decrease. Similarly, the waveform triggers, exhalation to inhalation, when airflow increases to a trigger threshold. Different interim rate targets have different trigger threshold functions that allow easier triggering as the interim rate targets decrease.

Abstract: The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.

Abstract: The configurations herein are directed to a sleep trolley system for automation of sleep disruption. Such a unique system often includes a platform support system; a natural habitat chamber configured for an animal subject, wherein the natural habitat chamber is removeably disposed thereon the platform support system; an agitator disposed therein the natural habitat chamber, wherein the agitator is configured with a first magnetic component to provide magnetic coupling; a trolley affixed to the platform support system; wherein the trolley is configured with a second magnetic component, wherein the second magnetic component exerts a magnetic attraction force with the first magnetic component coupled to the agitator as disposed therein the natural habitat chamber; and a control system configured to move the trolley along a dimension of the platform support system so as to guide the agitator along a corresponding length of the natural habitat chamber via the magnetic attraction force.

Abstract: Detection and treatment of disordered breathing is disclosed, with treatment being primarily delivered using electrical stimulation of the diaphragm, either directly or by stimulating appropriate nerves.

Abstract: One aspect of the present disclosure relates to a system to facilitate at home neural monitoring. The system can include a wearable device and an external device. The wearable device can include an electrode configured to be placed behind a patient's ear to record an electroencephalogram (EEG) signal; an amplifier to amplify the EEG signal; a battery; and a wireless transmission system to transmit the amplified EEG signal. The external device can be configured to receive the amplified EEG signal and to perform analysis of the amplified EEG signal. In some instances, the external device can also provide neural stimulation (e.g., acoustic, visual, or electrical) to the wearable device in response to analysis of the amplified EEG signal.

Abstract: A method for calculating blood pressure based on pulse return wave transmission time, and a blood pressure monitor have been provided. The method includes the following steps: S1: collecting and storing pulse waveform data at a fingertip; S2: processing said pulse waveform data to obtain a heart rate and parameters of a plurality of pulse periods, detecting time axis coordinates of a primary wave starting point SPL1 of a pulse wave and a growth point SPL2 of a return wave in each of said pulse periods, and calculating a corresponding pulse return wave transmission time RWTT: RWTT=SPL2?SPL1; S3: calculating the pulse return wave transmission time RWTT in each of said pulse periods to form a RWTT array; and S4: calculating systolic and diastolic pressures based on said RWTT array and the heart rate.

Abstract: Methods and apparatuses for improving sleep by transdermal electrical stimulation (TES). In general, described herein are methods for applying TES to a subject, and particularly the subject's head (e.g., temple/forehead region) and/or neck with an TES waveform adapted to improve sleep, including reducing sleep onset (falling to sleep) more quickly and/or lengthening the duration of sleep. TES waveform(s) particularly well suited to enhancing sleep are also described herein.

Abstract: A breathing apparatus and system include a breathing apparatus having a display, an internal memory unit, and a processing unit, and optionally an interface for connecting at least an external memory unit to the apparatus; optionally an external memory unit connectable to the breathing apparatus via the interface; wherein the processing unit is in operative communication with the display, the internal memory unit, and/or the external memory unit when connected to the apparatus via the interface, and the processing unit is configured to provide on at least a portion of the display, a user selectable background stored on at least one of the internal and/or external memory unit, such as a background image, or a background color different than a factory default background color that is not selectable by a user.

Abstract: Systems and related methods for controlling delivery of a stimulus to a pinna of a subject with a stimulator worn on the pinna are described. A wearable stimulation device includes a mechanical, electrical, or other type of stimulator secured to a pinna of a subject. A personal computing device in communication with the wearable stimulation device controls delivery of stimuli and other aspects of operation of the device. The personal computing device presents various types of information relating to operation and control of the device to a user of the wearable stimulation device. In some aspects recommendations regarding neural stimuli and other stimuli or experiences to be delivered in association with the neural stimuli are provided via a computing system in communication with the personal computing device or the wearable stimulation device.

Abstract: An electrotherapeutic system for treating a visual disease is disclosed. The system includes a signal generator configured to generate a treatment waveform comprising a series of current pulses. Preferably, the current pulses have a peak current amplitude of 200 microamps or less. The system also includes a headset applicator comprising a headband and a headset. The headset has a magnetic slot configured to be mounted to a magnetic mount of the headband. The headset includes left and right eyecup electrodes each of which has a contact surface that is positioned for contact with a skin surface within left and right eye regions, respectively. Preferably, the contact surface of each of the left and right eyecup electrodes comprises an upper contact pad and a lower contact pad that have a total area in the range of about 1.10 cm2 to about 1.80 cm2. The headset is connectable to the signal generator and configured to deliver the treatment waveform to one or both of the left and right electrodes.

Abstract: A method, apparatus and computer program, in which a body of a wearable apparatus is maintained maintaining by a link in place at a given part of skin of the user. A sensor platform is movably supported sandwiched between the body and the skin and supported by the body movably with relation to the body towards and away of the skin, when the apparatus is worn by the user. A sensor is supported by the sensor platform. The sensor produces sensor signals corresponding to a property of the skin or underlying matter. The position of the sensor platform is adjusted by an actuator with relation to the skin.

Abstract: A mass spectrometry data processing apparatus having a function of displaying a plurality of MSn spectra in an arranged manner is allowed to display these MSn spectra in a state where a user can easily grasp presence or absence of a common neutral loss. A mass spectrometry data processing apparatus 20 that displays, on a display screen, an MSn spectrum resulting from mass spectrometric analysis of n?1 stage dissociation, where n is integer of two or more, of an ion, includes: a precursor ion identifying section 32 configured to identify, for each of a plurality of MSn spectra, a mass-to-charge ratios m/z of a precursor ion from which the MSn spectra are obtained; and a spectrum aligning section 33 configure to display the MSn spectra on the display screen in a vertically arranged manner such that positions of the mass-to-charge ratios m/z of the respective precursor ions are located at a same horizontal position of the display screen.

Abstract: An anesthesia system includes a volume reflector, a breathing circuit, a processing unit, and a display operatively connected to the processing unit. The processing unit is configured to provide a status indicator on the display for gas in the volume reflector, the status indicator including a graphical representation of an extent of a driving gas of the volume reflector and/or a patient gas in the volume reflector, and/or a flow of gas and a direction of the flow in the volume reflector, and/or a waste gas flow out of the volume reflector relative a fresh gas flow in the system, and/or a re-breathing fraction (RBF), and/or a balance between the fresh gas flow and patient uptake and/or leakage of gas from the breathing circuit.

Abstract: A system for influencing the senses of a person in a room for measuring and/or influencing physiological parameters of the person is provided. The person is substantially stationary and lying in the room during the measurement and/or influencing. The system includes a sound insulating apparatus for screening off acoustically active devices with respect to the person. The acoustically active devices serve for measuring and/or influencing the physiological parameters in the room, and an optical display apparatus for offering optical stimuli and/or signals for the person in the field of view of the person.

Abstract: Systems and related methods for controlling delivery of a stimulus to a pinna of a subject with a stimulator worn on the pinna are described. A wearable stimulation device includes a mechanical, electrical, or other type of stimulator secured to a pinna of a subject. A personal computing device in communication with the wearable stimulation device controls delivery of stimuli and other aspects of operation of the device. The personal computing device also controls delivery of a sound signal (for example, music) to the user of the stimulation device in association with the neural stimulus. In some aspects recommendations regarding neural stimuli and other stimuli or experiences to be delivered in association with the neural stimuli are provided via a computing system in communication with the personal computing device or the wearable stimulation device.

Abstract: The present invention provides for eyeglasses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses.

Abstract: A system for monitoring sleep efficiency includes a measuring device and a data processing device. The measuring device is for measuring body temperature of a subject and for outputting temperature data associated with the body temperature. The data processing device receives the temperature data, and is programmed to process the temperature data so as to determine sleep efficiency. The processing of the temperature data includes constructing a curve of the body temperature over asleep episode, finding a saddle point of the curve occurring for a first time, treating a time instance at which the saddle point occurs as a sleep-onset time point at which the subject falls asleep, and determining the sleep efficiency according to the sleep-onset time point.

Abstract: Light therapy is provided to a subject using a system and/or method. The light therapy includes the administration of electromagnetic radiation to the eyeball of the subject underneath the eyelid of the subject while the eyelid of the subject is closed (e.g., as the subject sleeps). The light therapy algorithm may be designed to impact melatonin and/or serotonin levels within the body of the subject in a therapeutically beneficial manner. For example, the light therapy algorithm may be designed to impact melatonin and/or serotonin levels to treat one or more of a sleep and/or mood disorder (e.g., seasonal affective disorder, non-seasonal depression, Circadian rhythm disruption), or other disorders treatable with control over melatonin and/or serotonin levels in the body.

Abstract: In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied.

Abstract: There is provided an information processing device including: a sleep environment controlling unit configured to, when exerting control of, on the basis of a result of forecast of a transition of a depth of sleep of a user at least in a period from a first time to a second time, a sleeping environment of the user such that the depth of sleep at the second time falls below a first depth-of-sleep threshold value estimated as an upper limit of a first depth-of-sleep region in which the user is likely to awake, decide a temporal pattern of the control in the period from the first time to the second time in accordance with a temporal pattern of the transition.

Abstract: A method to provide non-invasive neurostimulation to enhance a subject's proficiency in an exercise includes: (a) engaging a subject in a physical or mental exercise, the subject having no cognitive, physical or emotional impairment; (b) providing intraoral cutaneous stimulation of at least one of the subject's trigeminal nerve, facial nerve or hypoglossal nerve by delivering electrical pulses to one or more stimulators situated within the subject's mouth, the delivery of electrical pulses being (i) contemporaneously with and independent of the subject's engagement in the exercise, and (ii) independent of the subject's surrounding environment; and (c) repeating steps (a) and (b) on a periodic basis.

Abstract: Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a neural stimulation system that receives an indication of an ambient audio signal detected by a microphone. The system selects, from a profile, an audio signal including a fixed parameter and a variable parameter. The system sets the variable parameter to a first value. The system generates an output signal based on the fixed parameter and the first value, and provides the output signal to the speaker. The system measures a physiological condition of the subject, adjusts the variable parameter to a second value, generates a second output signal based on the fixed parameter and the second value of the variable parameter, and provides the output signal to the speaker to cause the speaker to provide modified sound to the subject.

Abstract: A method for inducing the feeling of a presence (FoP) in a subject by using a master-slave robotic system, the method including the steps of altering a visual perception of a surrounding environment of the subject, connecting the subject with a robotic master device so that the subject can move, move on or manipulate the robotic master device, connecting the subject with a robotic slave device, making the subject move, move on or manipulate the robotic master device so that the subject is directly or indirectly touched by the robotic slave device according to a movement of the robotic master device, wherein the robotic master device and the robotic slave device are operatively connected so that the subject receives at least one of spatially and temporally conflicting sensorimotor stimulation.

Abstract: Method, device (100) and system (200) for detection and quantification of the variation of eye damage caused by the blue and violet light of the visible spectrum comprising the steps of detecting the incident radiation on an individual's visual system; calculating the incident radiation within the range between 380 and 500 nm; establishing at least one threshold of incident radiation within said range; detecting if at least one threshold established for said range has been exceeded; warning of the excess of at least one threshold; measuring the exposure time to incident radiation; and inferring in the different ocular structures of an individual the effect of incident radiation and warning of such effect.

Abstract: A computer-implemented method of automating inductive bias selection includes a computer receiving a plurality of examples, each example providing a plurality of feature-value pairs. The computer constructs an inductive bias dataset which correlates each respective example in the plurality of examples with numerical indications of training quality. The numerical indications of training quality for each respective example are generated by creating a plurality of models, with each model corresponding to a distinct set of inductive biases. The training quality for each respective model is evaluated when applied to the respective example. The computer uses the inductive bias dataset to select a plurality of inductive biases for application to one or more new datasets.

Abstract: Methods, apparatuses and systems for controlling an alarm are set forth herein for reminding a user with assurance of sleep quality. The method includes receiving sleep information, determining a sleep status, determining whether duration of the sleep status reaches a pre-determined duration threshold, and based on a determination that the duration of the sleep status reaches the pre-determined duration threshold, outputting alarming information.

Abstract: A user monitoring device system includes a user monitoring device with a microphone and sensors to determine air quality, sound level/quality, light quality and ambient temperature near the user. A movement detection device detects a user's movement information. The movement detection device and the monitoring system assist to determine user sleep information and sleep behavior information. The microphone records user movement sounds detected by the movement detection device. The movement detection device is configured to cause the microphone to stop recording user movement sounds when the movement sounds are not directed to a sleep related parameter. In response to determining user sleep information or sleep behavior information the system is used for treatment of sleep or psychiatric disorders.

Abstract: One embodiment provides a system comprising at least one learner application module for receiving feedback data from at least one user via at least one electronic device, about information presented to the users by a presenter. The system further comprises at least one sensor for capturing contextual data associated with the users. The system further comprises a recommendation provider for collecting feedback data and contextual data from each learner application module and each sensor, respectively. The recommendation provider determines at least one personalized recommendation for each user based on the collected data and the presented information.

Abstract: Introduced are methods and systems for: gathering human biological signals, such as heart rate, breathing rate, or temperature; analyzing the gathered human biological signals; and controlling home appliances based on the analysis.

Abstract: A stress-measuring device (10) and method determines a level (15) of stress of a user (1), in particular long-term stress. The stress-measuring device (10) includes an input interface (12) for receiving a skin conductance signal (11) indicating the skin conductance of the user (1), the skin conductance signal (11) over time forming skin conductance trace data (13). The stress-measuring device (10) further includes a processing unit (14) for processing the skin conductance trace data (13). The processing unit (14) determines, over at least a portion of the skin conductance trace data (13), values of a rise time (tr) between at least two different points of the skin conductance trace data (13), a frequency distribution of the rise time (tr) values, and the level (15) of stress of the user (1) based on the determined frequency distribution.

Abstract: In an embodiment, a method includes determining a target frequency corresponding to a target brain state and stimulating a brain of a user using feedback to attempt to achieve the target brain state in the user. The stimulating step may include measuring an electrical output of the brain of the user received from one or more sensors coupled to the user, determining a current frequency associated with the brain of the user based on the measured electrical output, and determining a difference between the current frequency and the target frequency. When the difference between the current frequency and the target frequency is greater than a predetermined amount, the method includes sending a signal to the brain of the user through one or more pathways. The signal may have a frequency operable to modify the current frequency associated with the brain of the user towards the target frequency.

Abstract: A device for delivering caloric vestibular stimulation to an individual, includes: (a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering a first thermal stimulus; (b) an input unit for receiving a user input indicating efficacy of said first thermal stimulus, and (c) a controller operatively associated with said earpiece and said input unit for: (i) controlling said earpiece to provide said first thermal stimulus, and (ii) receiving a signal corresponding to the user input and generating a control signal to control the earpiece and delivering a subsequent thermal stimulus different from said first thermal stimulus. In some embodiments, each thermal stimulus is an actively controlled time varying waveform stimulus.

Abstract: An apparatus for inhibiting melatonin synthesis in a horse comprises a blinker having an internal surface of which at least a part is diffusing. A source of light is positioned for direction into the horse's eye by the diffusing-surface. The light source and diffusing surface are configured such that the light directed into the horse's eye is blue.

Abstract: A dream stimulator may include a substrate and a plurality of electrodes positioned along a first side of the substrate. The stimulator also may include a stimulator coupled to the substrate. At least one lead may couple the plurality of electrodes to the stimulator. Additionally, a band may be positioned along a second side of the substrate and about each of the plurality of electrodes.

Abstract: A method to provide non-invasive neurostimulation to enhance a subject's proficiency in an exercise includes: (a) engaging a subject in an exercise, the subject having no cognitive, physical or emotional impairment with respect to the exercise; (b) providing stimulation of at least one of the subject's trigeminal nerve, facial nerve or hypoglossal nerve by delivering electrical pulses generated by a signal generator to the subject's skin via at least one electrode in contact with the subject's skin, the delivery of electrical pulses being (i) contemporaneously with and independent of the subject's engagement in the exercise, and (ii) independent of the subject's surrounding environment; and (c) repeating steps (a) and (b) on a periodic basis.

Abstract: A method monitors a person's sleep parameters, sleep activities, sleep state, or awake status sleep. At least one of a person's motion, movement and gesture is detected for determining a person's sleep parameters, sleep activities, sleep state, or awake status. The at least one of a person's motion, movement and gesture is communicated to a user monitoring device that includes at least two elements selected from: a proximity sensor; a temperature sensor/humidity sensor; a particulate sensor; a light sensor; a microphone; a speaker; two RF transmitters (BLE/ANT+WIFI); a memory card; and LED's.

Abstract: Provided are a sleep awaking system and a sleep awaking method.

Abstract: An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.

Abstract: A wireless implantable system is provided that is externally powered and comprises of a closed-loop feedback for treating both patients with obstructive and central sleep apnea. A method is provided for treating sleep apnea using an implantable device. The method comprises sensing an inspiration (IN) signal representative of inspiration experienced by a patient from a respiratory surrogate signal and sensing a respiratory effort (RE) signal representative of an amount of effort exerted by the patient during respiration.

Abstract: A computer-implemented method for the automated driving of a vehicle. The method may include coordinating a planned vehicle path using a path planner application. The path planner application may receive information based on inputs to sensors disposed on the vehicle. The method may include sending a command to one or more vehicle systems to control the vehicle to follow the planned vehicle path. While the vehicle follows the planned vehicle path, the method may include receiving an indication that the path planner application is not meeting a threshold performance level. After receiving the indication that the path planner application is not meeting the threshold performance level, a command is sent to one or more vehicle systems to control the vehicle to follow a temporary and irregular full vehicle movement to alert a vehicle driver. The temporary and irregular full vehicle movement may be a full vehicle side-to-side wobbling movement.

Abstract: Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.