Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract: Multispectral filter arrays and methods of making and using the arrays are described herein. Multispectral imaging systems and methods of making and using the systems are also described. A multispectral filter array includes a mosaic of light sensitive elements that includes a first element sensitive to a first narrow spectral region, a second element sensitive to a second narrow spectral region, and a third element sensitive to a third narrow spectral region. A multispectral imaging system includes an illumination system having at least three lighting elements, each of which are configured to transmit light at a different wavelength, and the multispectral filter array.

Abstract: The present invention relates to a device for evaluating condition on skin or hair. The device provides one extension supporting a hydration meter suitable for measuring hydration values in areas difficult to measure (e.g., skin in scalp area) and; a separate extension supporting a camera for capturing images of an area of skin or hair and transferring said image to computer. Data from these sources are evaluated and scored. The multiple data points are used to provide a highly targeted product best suited for each individual consumer.

Abstract: A system for measuring skin hydration at a measurement site with a independent measurement probe and a portable data processing system. Wireless communications enable the transfer of commands and data between the probe and portable data processing system. The portable data processing system can comprise a wireless tablet or smartphone. The portable data processing system provides input functions and output functions on its display and includes a camera for imaging the measurement site.

Abstract: The spacer attachment for a dermatoscope comprises an outer sleeve (12) including an attachment end configured for releasable attachment to the illumination head of a dermatoscope and a contact end intended to be placed on the skin of a patient at an examination location. A filter insert (30) is releasably attached in the outer sleeve (12) by rotation about the central axis of the outer sleeve (12), wherein the filter insert (30) includes a viewing plate (52) intersected perpendicularly by the central axis of the outer sleeve (12). The filter insert (30) is releasably attached to the outer sleeve (12) by a rotation snap device comprising at least one resilient snap hook (44) which is arranged at the outer circumference of the filter insert (30) and resiliently engages around a projection (26) provided at the inner wall of the outer sleeve (12).

Abstract: The present invention is a mood sensing and communicating system and method that includes a biometric sensor configured to sense biometric information from a person. A mood interpretive system is supported on a computing device or on a remote server. The mood interpretive system is in communication with the biometric sensor and is configured to assign a psychological or emotional mood state with the sensed biometric information. A communication system is supported on the computing device and is configured to communicate the assigned psychological mood state across an Internet to a web-site for positing on a web page. The method includes sensing biometric information from a user with a biometric sensor, associating a psychological mood state with the sensed biometric information with a mood interpretive module, and communicating the assigned psychological mood state to a web-site supported on a server across an Internet.

Abstract: In one aspect, there is disclosed a system and method for rapidly and passively identifying changes in the number of open pores in the skin of an individual in response to a stimulus without contacting the individual. This is accomplished by using a thermal camera that is sensitive in the mid-wave or long-wave infrared (3-5 or 8-14 ?meters) to observe and/or count the number of skin pores opening in response to questions being asked of the individual.

Abstract: A human skin moisture measuring device having an interdigitated resistive sensor formed on a plate-like transparent support is described, with a face designed to be placed into contact with the skin to be subjected to the moisture degree measurement. The device further comprises image sensing means turned towards the opposite face of the support and a lighting device arranged sideways relative to the support to direct the light radiation in the support at a prefixed angle. Means for processing the signal coming from the interdigitated resistive sensor and from the image sensing means give as output a value of the measured moisture degree that is normalized with respect to the actual surface of contact between skin and sensor.

Abstract: To provide a moisture meter which can detect a heat-illness risk-index earlier and which is effective to assist a subject carry out a proper moisture adjustment includes: a moisture measurement unit held by an armpit of a subject and which measures the amount of moisture of the subject through contact with a skin surface of the armpit, a sensor unit which measures the temperature and humidity of the environment of the subject, and a processing unit which obtains the amount of moisture of the subject from the moisture measurement unit, which sets a Wet-Bulb Globe temperature (WBGT) value from the relationship between the temperature and humidity from the sensor unit and which obtains the heat-illness risk-index by referring to a relation table between the amount of moisture of the subject and the Wet-Bulb Globe temperature value.

Abstract: A method and system is provided for performing cosmetic analysis of a subject. Assessment data of observable characteristics of each of a plurality of defined body areas of a subject is converted to weighted data for each of the plurality of defined body areas. This weighted data is analyzed to generate cosmetic analysis data. This cosmetic analysis data can include an apparent age of the subject. The cosmetic analysis data is then provided to a user such as a cosmetic surgeon, beauty therapist or the subject themself. The system and method can be further adapted to perform treatment diagnosis for the subject based on the cosmetic analysis data.

Abstract: A method for diagnosing the onset of necrosis, decubiti, and/or decubitus ulcers in the skin of a patient. Included is a topical product accessed in liquid form and applied to the skin. The product displays thermochromic temperature change when the product comes into contact with human skin tissue to identify body parts at risk for tissue necrosis by the color differences.

Abstract: An output device that outputs a schematic view showing a position of a diseased part of a human body, comprises: a read-out unit adapted to read out a plurality of schematic views output from a storage unit adapted to store the schematic views, and a control unit adapted to output the plurality of schematic views read out by the read-out unit to an output unit, wherein the read-out unit selects a schematic view to be read out based on an output format that has been set by a user.

Abstract: An adherent device to monitor a tissue hydration of a patient comprises an adhesive patch to adhere to a skin of the patient. At least four electrodes are connected to the patch and capable of electrically coupling to the patient. Impedance circuitry is coupled to the at least four electrodes to measure a tissue resistance of the patient, where the circuitry is configured to determine the tissue hydration in response to tissue resistance. The circuitry may comprise a processor system and the tissue resistance may correspond to a change in patient body fluid. The impedance circuitry is configured to measure the hydration signal using at least one low measurement frequency, which may be in the range of 0 to 10 kHz. Multiple measurement frequencies may be used and the hydration signal may include a tissue reactance measurement.

Abstract: The present invention includes an integrated system and methods for patient treatment, the system includes a hospital bed; a plurality of patient diagnostic and treatment devices connected to a network, wherein each of the devices can communicate to a network and exchange information with the network about the care of a patient; and a processor accessible adjacent to the bed and connected to the network to integrate information obtained from the devices through the network with one or more additional sources of information databases, wherein the processor can communicate to one or more patient treatment devices either directly or via the network and the processor directs the one or more patient treatment devices to change the treatment of the patient.

Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract: A skin state analyzing method for analyzing the skin state of an examinee using an image of the skin of the examinee includes an analyzing step of analyzing at least one of texture/pores, spots, skin tone, and sebum of the skin from the image, a storing step of storing the image and an analysis result obtained from the analyzing step in association with skin examination date/time information and examinee information, a display screen generating step of generating a screen displaying the image and the analysis result of the examinee stored in the storing step, and an output step of outputting the information generated in the display screen generating step.

Abstract: Technologies adapted for using acoustic pulses to diagnose skin conditions are disclosed. A series of acoustic pulses may be directed at a skin through the speaker of a device. Acoustic reflections may be received at a microphone. The reflections may be sampled and stored as echogram data. The echogram may be analyzed to identify potential skin conditions.

Abstract: A clip-style pulse sensor may be adapted to apply limited, even pressure to a patient's tissue. A clip-style sensor is provided that reduces motion artifacts by exerting limited, uniform pressure to the patient tissue to reduce tissue exsanguination. Further, such a sensor provides a secure fit while avoiding discomfort for the wearer.

Abstract: The invention relates to a method for objectively measuring skin phototype by reflectance spectrophotometry. The improved method correlates well with clinician-based assessments and is non-invasive, rapid and accurate.

Abstract: A method for determining skin irritation is provided. The method uses a source of cross-polarized light to illuminate and area of skin. The cross-polarized light is used to detect subsurface indicators of skin irritation such as erythema, inflammation, dryness, or innervation. The subsurface indicator is then assigned a score.

Abstract: The invention relates to sweat activity measurement, e.g. for determining a physiological state of a subject, embodied by a method as well as a kit with an immittance measuring circuit and electrodes with contact electrolyte. Sweat activity is considered a transport phenomenon and can be defined as a flux, e.g. gram water per skin area per second. Prior art methods determining water absorbed per gram dry stratum corneum measures skin moisture and do not truly reflect sweat activity. A periodic signal with frequency of 60 Hz or lower is applied to reduce contribution from complex admittance of the skin, and skin conductance is measured as a degree of sweat activity. The contact electrolyte allows filling of sweat ducts with sweat from sweat glands, this may be characterized in that it does not substantially fill the sweat ducts when being positioned on the skin and/or in that it has a re-absorption time constant from the sweat ducts into the Epidermis of less than 15 min.

Abstract: Provided is a moisture meter that can easily measure a moisture content of a subject and can be effectively used as means for assisting the subject in appropriately regulating the moisture content. A moisture meter for measuring a moisture content of a subject includes: a moisture measuring unit that is held in an armpit of a subject so as to measure a moisture content of the subject, the moisture measuring unit including measurement current supply electrode portions and voltage measurement electrode portions that make contact with a skin surface of the armpit; and a temperature measuring unit that is held in the armpit of the subject so as to measure the temperature of the subject.

Abstract: A method and apparatus for determining patient hydration levels is disclosed. The method includes measuring a skin turgor.

Abstract: An adherent device to monitor a patient for an extended period comprises a breathable tape. The breathable tape comprises a porous material with an adhesive coating to adhere the breathable tape to a skin of the patient. At least one electrode is affixed to the breathable tape and capable of electrically coupling to a skin of the patient. A printed circuit board is connected to the breathable tape to support the printed circuit board with the breathable tape when the tape is adhered to the patient. Electronic components electrically are connected to the printed circuit board and coupled to the at least one electrode to measure physiologic signals of the patient. A breathable cover and/or an electronics housing is disposed over the circuit board and electronic components and connected to at least one of the electronics components, the printed circuit board or the breathable tape.

Abstract: A skin moisture measuring apparatus that measures moisture in a testee's skin includes an earphone plug that is connected to an earphone port of a smart device and connects the skin moisture measuring apparatus to the smart device; an oscillation signal generation unit that generates an oscillation signal; and a sensor unit that includes two or more contact portions exposed to the outside to be in direct with the testee's skin, modifies the oscillation signal depending on an electrical resistance corresponding to a moisture content in the testee's skin and formed between the two or more contact portions, and generates a measurement signal. In the skin moisture measuring apparatus, the sensor unit transmits the measurement signal to the smart device through the earphone plug.

Abstract: An abnormal skin area calculating system and a calculating method thereof are provided. The system includes an image capture module, a database, a skin analysis module, and a numerical calculation module. The database pre-stores at least one abnormal skin analysis data. The skin analysis module analyzes and marks an abnormal skin area in a skin image by using the skin analysis data. The numerical calculation module calculates a pixel area of the abnormal skin area graph, and calculates an actual skin area of a human body corresponding to the abnormal skin area graph with an area calibration parameter. The area calibration parameter is pre-stored in the database, or is generated by the numerical calculation module in calculating a transformation relation between a presented calibration length unit and a pixel distance unit according to a calibration object graph in the skin image.

Abstract: Apparatus are provided for monitoring a condition of a tissue based on a measurement of an electrical property of the tissue. In an example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least two conductive structures, each having a non-linear configuration, where the at least two conductive structures are disposed substantially parallel to each other. In another example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least one inductor structure.

Abstract: A system and method include a sensor overlying a target area of epidermis to aid in diagnosing subcutaneous fluid leakage. The system includes an antiperspirant and an adhesive coupling the sensor and epidermis. The antiperspirant mitigates moisture content variation of the target area, which the inventors discovered is a source of unreliable indications that an infiltration or extravasation event has occurred.

Abstract: An apparatus and method for non-invasive determination of hydration, hydration state, total body water, or water concentration by quantitative spectroscopy. The system includes subsystems optimized to contend with the complexities of the tissue spectroscopy, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance, and calibration transfer. The subsystems include an illumination subsystem, a tissue sampling subsystem, a spectrometer subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem.

Abstract: This invention provides devices, compositions and methods for determining the concentration of one or more metabolites or analytes in a biological sample, including cells, tissues, organs, organisms, and biological fluids. In particular, this invention provides materials, apparatuses, and methods for several non-invasive techniques for the determination of in vivo blood glucose concentration levels based upon the in vivo measurement of one or more biologically active molecules found in skin.

Abstract: An apparatus is configured to detect skin cancer using THz radiation. A high frequency source generates a high-frequency signal. A power splitter divides the high-frequency signal between a transmission branch and a reception branch. A first frequency multiplier multiplies the frequency of the high-frequency signal. A transmission antenna emits the multiplied high-frequency signal as THz radiation. A frequency generator generates a low-frequency signal. A mixer mixes the high-frequency and low-frequency signals to generate a mixed-frequency signal. A second frequency multiplier multiplies the mixed-frequency signal. A reception antenna device receives the THz radiation and generates a THz signal. The mixing device mixes the THz signal with multiplied mixed-frequency signal to generate a measurement signal. The evaluation device evaluates the measurement signal.

Abstract: The present invention includes a flexible sensor suitable for contact with skin comprising: a nanocomposite; and a top layer; where the sensor provides in-situ detection in sweat or other aqueous body fluids at the skin surface of at least one physiological parameter selected from the group consisting of a physiological salt component, temperature, moisture, humidity, or combinations thereof. The present invention further includes a method of fabricating a flexible sensor suitable for contact with skin comprising: electrospinning at least one polyamide-producing monomer to form a non-conductive polyamide substrate; attaching at least one plurality of conductive nanoscale attachments, wherein the nanoscale attachments are selected from nanotubes, nanoparticles, or combinations thereof, to form an intermediate layer; and functionalizing the intermediate layer to form a top layer.

Abstract: A system and method for effectively communicating information using at least one mode of communication is described, in which information recipients proximate to a communications device within a pre-determined space and during a pre-determined time period are identified, from whom physiological state information is obtained that, when coupled with other characteristics information, is used to select from a plurality of information elements at least one information element to better target the information elements. The information element is then provided to the communications device so that it may be provided to the information recipients in the pre-determined space in a manner that is sensed by the information recipients.

Abstract: An apparatus to measure skin moisture content, the apparatus including: an electrode unit comprising a reference (R) electrode, a current (C) electrode, and a measuring (M) electrode; an operational amplifier having an inverting input terminal connect with the R electrode, and having an output terminal connect with the C electrode; a first switch connecting the R electrode and the C electrode, and releasing a connection between the R electrode and the C electrode when the electrode unit contacts with the skin of a user; and a microcontroller controlling the connection between the R electrode and the C electrode via the first switch is provided.

Abstract: A computerized method and system for detection and quantification of changes in color on skin or internal tissue or organs within the human body. Digital images of the skin or tissue containing an area of interest are analyzed using the software of the invention, based on at least one channel of the LAB color system. The invention calculates the intensity and distribution of color present within the predetermined area of interest, and results in display of at least one color information attribute. The invention allows color calibration of the image to be performed in relation to a reference label having predetermined colors which surrounds the area of interest, prior to the analysis. The invention allows a threshold analysis to be performed, which graphically depicts the size and location of areas exhibiting significant change in color, which is a determinant factor in medical diagnosis.

Abstract: Among other things, on a two-dimensional electronic display are shown simultaneously: (a) at least a partial body view of a surface of the human model on which a location of a skin lesion on a corresponding real human has been indicated, and (b) an image of the lesion area that corresponds to the partial body view of the human model.

Abstract: The present invention relates to a system for measuring the input impedance of a skin/electrode interface and selectively modifying the input impedance of the monitoring circuit to match the measured input impedance. More particularly, a simplified method for correcting for input impedance mismatch between electronic monitoring circuitry and the skin/electrode interface. In accordance with one embodiment of the invention, an input impedance measuring circuit will interface with a microprocessor and a reconfigurable switch network to select the input impedance of the electronic monitoring circuitry, thus eliminating the impedance sensitivity of EMG or EKG instruments.

Abstract: A system and method are provided for a water reserve index. The method includes determining a lean water fraction of tissue for at least one tissue site and determining skin thickness for the at least one tissue site. The lean water fraction and skin thickness are combined to produce a water reserve estimate.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: The invention relates to a method and an apparatus for monitoring the autonomous nervous system of a sedated patient. According to the method, skin conductance is measured through a time interval. Average skin conductance values and the number of fluctuation peaks are in the interval are calculated and analyzed, and an indication is given of the state of pain/discomfort in the patient as well as the state of awakening in the patient. The invention is particularly applicable for use with anaesthetized or artificially ventilated patents, as separate output signals are automatically provided, indicating the need for analgesics and hypnotics, respectively.

Abstract: Among other things, on a two-dimensional electronic display, a representation is shown of a scanned image of a lesion on the skin of a real human. On the two-dimensional electronic display, a recommendation is indicated of a next diagnostic or treatment step to be taken, based on a computer-implemented analysis of the scanned image.

Abstract: Optical sensor devices, image processing devices, methods and computer readable code computer-readable storage media for detecting biophysical parameters, chemical concentrations, chemical saturations and blood count. In some embodiments, the image processing device receives a live still or video electronic image. Exemplary physiological parameters include but are not limited to a pulse rate, blood pressure, glucose, stroke volume of internal or external tissue (e.g. skin). A biophysical or physiological property is not limited to a cardiovascular or liver or the kidneys or to a cardiovascular disorder or to a pulmonary disorder. Exemplary chemical concentrations or saturation includes but not limited to a pH level, a glucose level, a urea nitrogen level, a CO2 concentration or saturation, or a oxygen concentration or saturation. In some embodiments the parameters are detected from a food or a beverage such as an alcohol, a dairy product, wine, a baked good, a fruit or a vegetable.

Abstract: In medical imaging, a fiducial marker facilitates tissue image correlation that allows for image analysis, normalization and correction of the optical exposure and spectral and spatial distribution in order to compensate for the surface reflections, sub surface tissue interactions and spatial orientation of the excitation and imaging axes to the subject tissue. Using a cross comparison, clinicians can model tissue image data in different forms in order to reference and compare data from various spectral components and or from different images. This may enhance human interpretation between images including the variations between images even when the spectral, spatial and optical conditions or the image resolution or sensitivity are compromised. Such may be used to assess cosmetic, moisturizing, therapeutic materials and treatments.

Abstract: According to certain embodiments, a medical imaging system includes an imager, a patient pallet, and a heating subsystem. The imager obtains measurement data of a patient. Further, the imager includes at least one electrical component that generates heat. The patient pallet supports the patient to be scanned by the imager. Further, the heating subsystem heats the patient pallet using the heat generated by the at least one electrical component of the imager.

Abstract: Targeted attribute transformation involves obtaining a digital image of the skin, selecting an individual skin attribute (an imperfection, such as a blemishes, pores, or wrinkles), extracting the individual skin attribute from the digital image by linear digital filtering on all the color channels, to obtain a contrast map in all three channels of the individual attribute, and adding or subtracting a fraction of the contrast map to the initial image, to obtain the skin image with transformed selected skin attribute.

Abstract: A human skin moisture measuring device having an interdigitated resistive sensor formed on a plate-like transparent support is described, with a face designed to be placed into contact with the skin to be subjected to the moisture degree measurement. The device further comprises image sensing means turned towards the opposite face of the support and a lighting device arranged sideways relative to the support to direct the light radiation in the support at a prefixed angle. Means for processing the signal coming from the interdigitated resistive sensor and from the image sensing means give as output a value of the measured moisture degree that is normalized with respect to the actual surface of contact between skin and sensor.

Abstract: A skin laxity measurement system which provides a skin laxity measurement tool and methods of measuring skin laxity.

Abstract: An apparatus for providing skin care information, the apparatus including: an electrode unit supplying a voltage to a user's skin and detecting a current signal in the user's skin; a measurement control unit measuring the user's skin moisture content and sweat gland activity by using the detected current signal; a data calculation unit deriving skin moisture content information by using the skin moisture content and the sweat gland activity, and generating skin care information corresponding to the skin moisture content information; and an information provider providing the user with the generated skin care information is provided.

Abstract: Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.

Abstract: According to various embodiments, a medical sensor assembly may be configured to switch between transmission and reflectance mode. Such sensors may include multiple optical sensing components that may be activated or silent, depending on the mode in use. A practitioner may switch between modes based on the particular situation of the patient or based on the signal quality.