Abstract: A detection system for multi-index coagulation items, including a housing, a detection and heating module, a battery module, a touch display screen and a mainboard. The housing includes an upper housing and a lower housing, and is an enclosed space formed by the upper housing abutting the lower housing; the mainboard is disposed between the upper and the lower housing, and is arranged in the enclosed space; the touch display screen is disposed at the upper surface of upper housing, and is connected with the mainboard; the detection and heating module is disposed in the enclosed space, and is arranged at the front end of lower housing for connecting with the mainboard; the battery module is arranged at the bottom of terminal of lower housing, and is connected with the mainboard; and a detection inlet for inserting and placing a detection card is disposed at the front end of housing.

Abstract: In one embodiment, a system for evacuating subdural hematomas includes an inlet configured to be placed in fluid communication with a subdural space, an irrigation reservoir in fluid communication with the inlet and configured to supply irrigation fluid to the inlet and the subdural space, an outlet separate from the inlet and also configured to be placed in fluid communication with the subdural space, and a pump in fluid communication with the outlet and configured to create negative pressure within the subdural space and evacuate fluid from the subdural space.

Abstract: Systems and methods for analysis of fluid leakage are disclosed. A system may include at least one processor configured to receive in real time, intracavitary video of a surgical procedure; analyze frames of the intracavitary video to determine an abnormal fluid leakage situation in the intracavitary video; and institute a remedial action when the abnormal fluid leakage situation is determined.

Abstract: Described here are methods and apparatuses for tracking a clot material within a lumen of a suction catheter. For example, an apparatus as described herein may include a flexible elongate body having a suction lumen, a first pair of electrodes within the suction lumen, a second pair of electrodes proximal to the first pair of electrodes, and a controller configured to track a clot material within the suction lumen based on signals from the first pair of electrodes and the second pair of electrodes.

Abstract: One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.

Abstract: Methods and a system are provided for assessing postpartum hemorrhage risk and postpartum hemorrhage stages in a clinical setting. Generally, a clinician may indicate that the mass of several bloody items, indicated in type and quantity, is to be measured using a scale. The mass of bloody items is compared to the known unused dry mass of such items in order to accurately determine the quantitative blood loss (QBL) of a patient at the bedside. The cumulative QBL can be updated by weighing additional items. Based on the cumulative QBL, the patient's vital signs, and other factors, a corresponding hemorrhage stage is identified and communicated to the clinician. Recommendations specific to the hemorrhage stage are provided to a clinician. Some recommendations are selectable actions that trigger automatic placement of medical orders and notifications to relevant medical services, such as a blood bank or anesthesia.

Abstract: The present specification describes a system for diagnosing or screening one or more pathologies in a patient. The system includes a headset with at least one microphone or accelerometer to passively receive vibrations generated by the cerebral vasculature of the patient's brain, computing devices coupled with the headset for processing the received vibrations to obtain a unique signal, and a signal analyzer to analyze the signal in order to determine if the data includes patterns uniquely indicative of at least one of tension headaches, migraines, depression, dementia, Alzheimer's disease, epilepsy, Parkinson's disease, autism, cerebral vasospasm and meningitis.

Abstract: An insertion tool for inserting a catheter into a body of a patient is disclosed. The insertion tool unifies needle insertion, guidewire advancement, and catheter insertion in a single device. In one embodiment, the insertion tool comprises a housing in which at least a portion of the catheter is initially disposed, a hollow needle distally extending from the housing with at least a portion of the catheter pre-disposed over the needle, and a guidewire pre-disposed within the needle. A guidewire advancement assembly is also included for selectively advancing the guidewire distally past a distal end of the needle in preparation for distal advancement of the catheter. In one embodiment a catheter advancement assembly is also included for selectively advancing the catheter into the patient. Each advancement assembly can include a slide or other actuator that enables a user to selectively advance the desired component.

Abstract: A method for determining upper gastrointestinal bleeding course includes the steps of: providing an upper gastrointestinal bleeding monitoring system including a bleeding detecting device, a transmission module, a signal processing device and a signal display; acquiring a time signal of RGB three primary colors of an upper gastrointestinal tract image with the bleeding detecting device; transmitting the time signal of RGB three primary colors by the transmission module to the signal processing device; calculating an intensity ratio of the time signal of RGB three primary color; evaluating the upper gastrointestinal bleeding course according to the intensity ratio of the time signal of RGB three primary color; and displaying the evaluation result on the signal display.

Abstract: A method and apparatus for a balloon catheter can be provided. The balloon catheter includes a catheter and a balloon, a plurality of measuring electrodes formed on a primary substrate extend around the catheter within the balloon. The primary substrate and secondary substrate is formed by a portion of a flexible resilient membrane. The membrane is coiled to form a roll, and a primary substrate is also coiled around a rolled secondary substrate. The coiled primary and secondary substrates is urged through a second lumen in the catheter from the proximal end thereof to a radial slot in the catheter communicating with the second lumen. The primary substrate is urged through the radial slot and wrapped around and bonded to the catheter to form the measuring electrodes as band electrodes.

Abstract: A method for determining emptying of upper gastrointestinal tract includes the steps of: providing an upper gastrointestinal monitoring system including a detecting device, a transmission module, a signal processing device and a signal display; acquiring a time signal of RGB three primary colors of an upper gastrointestinal tract image with the detecting device; transmitting the time signal of RGB three primary colors by the transmission module to the signal processing device; calculating an intensity ratio of the time signal of RGB three primary color; evaluating the upper gastrointestinal emptying according to the intensity ratio of the time signal of RGB three primary color; and displaying the evaluation result on the signal display.

Abstract: A detector and a method of its use with a guidewire to reduce the incidence of guidewires accidently being left inside patients during the placement of central venous (and other) catheters. In particular, an electronic detector detects whether a catheter has been placed over a guidewire and whether the guidewire has been removed thereafter. In addition, the distance the guidewire has progressed out the patient side of the detector housing which will correspond to the length of guidewire actually inside the patient and any time may be provided.

Abstract: A non-invasive system for sampling gastrointestinal microbiota with their associated environment for discovery, characterization, medical research, diagnostics, and treatment using an ingestible, non-digestible sampling capsule. The capsule device, with ports open for acquiring a sample of gastrointestinal microbiota and content, is placed inside an immediate or delayed release capsule. When the outer capsule dissolves according to its specifications, enteric fluid and content enters the sampling capsule through the ports triggering a hydrophilic stop to release a pulling force to close the ports by enveloping the capsule outer casing over the inner casing, capturing the sample, and holding it sealed until it completes passage through the digestive track, and is recovered from feces for analysis.

Abstract: An electromagnetic (EM) probe for monitoring one or more biological tissues. The EM probe comprises a cup shaped cavity having an opening and an interior volume, a circumferential flange formed substantially around the cup shaped cavity, in proximity to the opening, at least one layer of a material, for absorbing electromagnetic radiation, applied over at least one of a portion of the circumferential flange and a portion of the outer surface of the cup shaped cavity, and at least one EM radiation element which performs at least one of emitting and capturing EM radiation via the interior volume.

Abstract: Example embodiments presented herein relate to solutions for analyzing and/or classifying microwave scattering data. The analyzing and/or classifying may be utilized for estimating an internal condition in an enclosed volume.

Abstract: A neuromodulation catheter in accordance with a particular embodiment includes an elongate shaft and a neuromodulation element operably connected to the shaft. The shaft includes a proximal hypotube segment at its proximal end portion and a jacket disposed around at least a portion of an outer surface of the hypotube segment. The jacket may be made at least partially of a polymer blend including polyether block amide and polysiloxane. The neuromodulation element includes a distal hypotube segment and a tubular jacket disposed around at least a portion of an outer surface of the distal hypotube segment. The jacket has reduced-diameter segments spaced apart along its longitudinal axis. The neuromodulation element further includes band electrodes respectively seated in the reduced-diameter segments and respectively forming closed loops extending circumferentially around the jacket.

Abstract: A nerve electrode cuff includes an electrode and a cuff body.

Abstract: An apparatus for locally controlling smooth muscle tone includes a first electrode for insertion into an artery; a barrier for preventing the first electrode from contacting an arterial wall; a second electrode; a power supply; and a controller for coupling the power supply to the electrodes. The controller is configured to cause the electrode to maintain a waveform for controlling polarization of smooth muscle tone.

Abstract: The present invention relates to a device and a method for collecting a sample of colorectal mucocellular layer excreted immediately following the natural act of defaecation from the surface of the anal area of a human subject, and preservation and analysis of the collected sample for detecting diagnostically informative disease biomarkers.

Abstract: Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced.

Abstract: An physiological data acquisition apparatus includes three or more leads, at least one AC current source, a switching mechanism structured to selectively couple the current source to selected lead pairs to inject an AC current across the selected lead pairs which produces an AC voltage across the selected lead pair, and a processing device. The processing device is structured to (i) determine an impedance across the current selected lead pair based on the AC voltage, (ii) determine whether the impedance is less than a predetermined threshold, (iii) if the impedance is less than the predetermined impedance threshold cause the current selected lead pair to be used for generating physiological parameter data, and (iv) if the impedance is not less than the threshold cause the switching mechanism to couple the at least one AC current source to a new selected pair of the leads.

Abstract: A system and method for detection of calorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract: Techniques are disclosed for monitoring the flow of blood returning to a patient from an extracorporeal therapy machine, such as a hemodialysis machine or an apheresis machine. Blood returning from such a machine is pumped, typically by a peristaltic pump, which returns the blood in pulsed flow or pulses. This flow can be sensed by Doppler flow sensors or accelerometers as it returns to the patient. If the flow is interrupted by dislodgement of the venous access needle, or by leaking of blood from the needle, these sensors will detect significantly different flow or vibrations. A controller can then cease therapy, alert a caregiver, or sound an alarm.

Abstract: A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample.

Abstract: Disclosed is a system for real-time detection and annunciation of blood associated with menstruation and surgical wounds. The system comprises blood detection means, communication means for relay of blood detection information, and annunciation means to inform the user of the emanation of blood. Various system embodiments include local and remote as well as covert and non-covert annunciation to users or medical personnel, various forms of real-time blood detection sensors, blood analysis capability, and smart bandage telemetry.

Abstract: An apparatus comprises a catheter comprising a first electrode. The apparatus also comprises a second electrode electrically attached to a person and coupled to the first electrode via the person's tissue. Logic is coupled to the electrodes and generates an electrical signal that is provided through the electrodes and computes an impedance or conduction velocity associated with the electrodes based on the electrical signal. The logic stores a threshold against which said computed impedance or conduction velocity is compared by said logic.

Abstract: A liquid leakage detection system requiring no power supply from an outer source and configured to be relatively simple and moderate in price. A liquid leakage detection system (10) including an infusion tube (11), a syringe needle (12) coupled to the infusion tube (11), an absorbent element (16) adapted to be placed in the vicinity of a point (12a) of the syringe needle (12) to be pricked through a patient skin and a sensor unit (14) located on an upper side or within the absorbent element (16).

Abstract: A pad is disclosed having a grid of absorbent structures (e.g., squares) formed on the pad. The pad may be used to quantify or otherwise assess blood loss by a patient. For example, blood lost by the patient and absorbed by the pad may be quantified by counting the number of saturated squares on the pad and taking into account the known absorbance of each square.

Abstract: A method to detect internal bleeding complications. The method includes determining, by an impedance assessment unit, a bioimpedance value at each of a plurality of frequencies. The method further includes normalizing, by the impedance assessment unit, each bioimpedance value at each frequency to a calibration bioimpedance value at that same frequency to produce a set of normalized bioimpedance values at the plurality of frequencies. The method also includes computing a bleed indication value based on the set of normalized bioimpedance values; and generating an alarm indicative of a bleed complication based on a comparison of the bleed indication value to a threshold.

Abstract: A brace device for the support of a wearer. The brace device comprises a flexible smart fabric, operable to partially or substantially enclose and/or lie adjacent to one or more portions of the thoracic, lumbar and/or cervical portions of the spine of the wearer. Fabric hardening means are provided, operable to partially or substantially harden one or more regions of the smart fabric upon application of an activating stimulus, thereby to prohibit, restrict and/or resist movement of one or more portions of the spine of the wearer. One or more predetermined regions of the smart fabric are in a substantially flexible configuration when the fabric hardening means are not activated, facilitating positioning, fitment and/or adjustment of the device around the wearer.

Abstract: An EIT system 1 adapted to detect internal bleeding in a body portion, the EIT system 1 comprising a plurality of electrodes 3 adapted in use to extend in a substantially linear orientation across one side only of the body portion and to be applied in electrical contact with the skin of the body portion, a current source adapted to cyclically apply an electric current between one pair of the electrodes 3, a voltage measuring means to measure the voltage across each of the other pairs of the electrodes resulting from the current, a data collection system 2 and a data analysis system 4 to analyse data resulting from the voltages that are measured by the voltage measuring means, wherein the analysis system 4 is configured to obtain quantitative information related to amounts and rates of conductive tissue changes occurring in the body, based on an EIT analysis equivalent to that obtained from data derived from electrodes spaced around the full perimeter of the body portion.

Abstract: An EIT system 1 adapted to detect internal bleeding in a body portion, the EIT system 1 comprising a plurality of electrodes 3 adapted in use to extend in a substantially linear orientation across one side only of the body portion and to be applied in electrical contact with the skin of the body portion, a current source adapted to cyclically apply an electric current between one pair of the electrodes 3, a voltage measuring means to measure the voltage across each of the other pairs of the electrodes resulting from the current, a data collection system 2 and a data analysis system 4 to analyse data resulting from the voltages that are measured by the voltage measuring means, wherein the analysis system 4 is configured to obtain quantitative information related to amounts and rates of conductive tissue changes occurring in the body, based on an EIT analysis equivalent to that obtained from data derived from electrodes spaced around the full perimeter of the body portion.

Abstract: Devices and a system for detection of blood within in-vivo fluids are provided. A device comprises a housing that includes a gap. The gap has at least one opening through which in-vivo fluids may enter and/or exit the gap. The device further comprises an illumination source for illuminating the in-vivo fluids in the gap, a light detector for detecting light which passes through the in-vivo fluids in the gap, and flexible fins disposed on the housing in the vicinity of the gap's opening for covering the opening when the fins are folded and for pumping fluids into and out of the opening by repeated closure and opening of the opening by the fins, due to repeated peristaltic waves. This pumping effect may lead to continuous flow of fluids into and out of the opening and thus into and out of the gap of the device.

Abstract: Provided is a fluorescence observation apparatus including a light source; a section generating a fluorescence image of an object; a section generating a reference image of the object; a section generating a corrected image in which emphasized are pixels of the reference image corresponding to pixels each having luminance value equal to or more than a first threshold value in the fluorescence image; a display unit displaying the reference image or the corrected image; a bleeding state determining section determining whether or not a bleeding region of the subject detected based on the reference image is more than a predetermined range; and a section switching between displaying the reference image on the display unit if the determining section determines that the region is not more than the range, and displaying the corrected on the image display if the determining section determines that the region is more than the range.

Abstract: Novel prognosis methods associated with cases of postpartum haemorrhage providing a predictive test enabling practitioners to provide better management of patients suffering from postpartum haemorrhage. Different risk factors exist on which a score allowing prediction of the need to carry out invasive procedures to stop bleeding has been developed.

Abstract: An EIT system (1) adapted to detect internal bleeding in a body portion, the EIT system (1) comprising a plurality of electrodes (3) adapted in use to extend in a substantially linear orientation across one side only of the body portion and to be applied in electrical contact with the skin of the body portion, a current source adapted to cyclically apply an electric current between one pair of the electrodes (3), a voltage measuring means to measure the voltage across each of the other pairs of the electrodes resulting from the current, a data collection system (2) and a data analysis system (4) to analyze data resulting from the voltages that are measured by the voltage measuring means, wherein the analysis system (4) is configured to obtain quantitative information related to amounts and rates of conductive tissue changes occurring in the body, based on an EIT analysis equivalent to that obtained from data derived from electrodes spaced around the full perimeter of the body portion.

Abstract: A diagnostic system includes sensors with at least one being a diagnostic device comprising one or more solid state light sources used in a differential measurement. A software application capable of generating physiological information based on the sensors is operable on a control system adapted to receive, store and process the physiological information. The control system includes a touch-screen, circuitry for obtaining position information from a location sensor, and a wireless transceiver to transmit wireless data including the physiological information over a wireless link and is further capable of receiving voice and manually entered input signals. A host includes a digital file for receiving and storing the wireless data, control logic to process the wireless data to generate a status of the user, memory for recording the status, and an output for communicating the status over a communication link to display output devices located remotely from the host.

Abstract: A catheter-based medical device includes a catheter that is configured and arranged for at least partial insertion into a patient and that defines at least one lumen that is configured and arranged to receive a first fluid. A conductive-fluid detector is coupled to the at least one lumen and is configured and arranged to detect when a second fluid is disposed within the at least one lumen that is more conductive than the first fluid. The conductive-fluid detector includes a plurality of axially-positioned bodies, each body defining a lumen. The lumens of the axially-positioned bodies are aligned to form a shared lumen in fluid communication with the at least one lumen of the catheter. Spaced apart electrodes are disposed within the shared lumen.

Abstract: Devices and methods for guidewire assisted placement of catheters into blood vessels are described. Some of the devices and methods relate to automated or partially automated or assisted insertion and placement of an intravenous catheter into a vein or artery of a patient. Other of the devices are blood draw devices and methods for insertion and placement of an intravenous device into a vein or artery of a patient or to withdraw a blood sample from the patient. The devices also provide for guide wire tip inspection after use.

Abstract: An access site disconnection system and method are disclosed. Radio frequency transmitters and receivers are placed near an access site. When a patient receives dialysis treatment, wetness may arise from blood if the access needle becomes disconnected from the access site. Radio-frequency transmitters are mounted on or near gauze or other absorbent material placed adjacent the access site, as are radio-frequency receivers. After the sensors are placed, the dialysis machine and radio-frequency control circuit may be initialized or baselined, and dialysis treatment, such as hemodialysis, begun. If blood leaks from the access site, such as if the access needle is dislodged, the blood attenuates the radio frequency transmissions, which are detected by the receivers. A signal is sent to a controller or to an output device to raise an alert or sound an alarm.

Abstract: The invention is directed to methods for diagnosing reperfusion/non-reperfusion hemorrhage and predicting cardiac arrhythmias and sudden cardiac death in subjects comprising using imaging techniques to detect regional iron oxide deposition. The invention also provides treatment methods for subject at increased risk of sudden cardiac death.

Abstract: A monitor for an extracorporeal therapy access site is disclosed. The monitor includes a bandage atop or adjacent the access site and a sensor for monitoring the bandage. The bandage includes a layer of polymer that expands when wetted with blood. The expansion causes a break in continuity of the sensor, or in an alternate embodiment, causes a sensor to cease detecting a target. When the break occurs, the control circuit monitoring the bandage sends a signal that a break has occurred, and a remote monitor then takes appropriate action, such as ceasing therapy, sending an alert, or sounding an alarm. In another embodiment, connecting wires in a continuity circuit are held apart by a polymer that dissolves when contacted by blood. If a leak occurs and a small portion of the polymer dissolves, the wires make contact, thus detecting a blood leak.

Abstract: A system and method for detection of calorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract: A bleeding detection unit in a surgical system processes information in an acquired scene before that scene is presented on a display unit in the operating room. For example, the bleeding detection unit analyzes the pixel data in the acquired scene and determines whether there are one or more initial sites of blood in the scene. Upon detection of an initial site of blood, the region is identified by an initial site icon in the scene displayed on the display unit. In one aspect, the processing is done in real-time which means that there is no substantial delay in presenting the acquired scene to the surgeon.

Abstract: An apparatus and method for capturing sensor readings relating to one or more blood flow attributes of a patient at or around a puncture site when the patient is being subjected to hemostasis process by a health care provider. A wide range of different sensor technologies and component configurations can be utilized. The apparatus can operate as a fully stand-alone device, a fully integrated component of a hemostasis treatment tool, or any configuration between the two polar extremes of integration/stand-alone.

Abstract: One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.

Abstract: A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage.

Abstract: A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage.

Abstract: An apparatus for determining an indicator parameter relating to a subject comprising at least an input line for receiving electrical signals coming from a electrodes, receiving a signal coming from a peripheral sensor predisposed to operate in a predetermined peripheral section of the subject's body; a control unit connected to the input line and configured for determining a value of an indicator value (iHAT) as a function of the instant of generation (TGj) of a pressoric wave in relation to the heartbeat.

Abstract: A method of detecting bleeding from a wound including: providing, on a support, a substantially non-volatile agent capable of forming a volatile agent on contact with blood; disposing the non-volatile agent on the support at or near the wound; providing a probe for detection of the volatile agent; disposing the probe for detection of the volatile agent at a distance from the support; generating a flow of air in a direction from the support to the probe; monitoring the formation of volatile agent by the probe, thereby detecting a bleeding of the wound. Also disclosed are a system and a disposable device for use in the method.