Abstract: A communication system is provided for a patient featuring a cushion with an opening for receiving the face of the patient. The cushion includes a microphone for receiving audible signals from the patient and one or more speakers for delivering audible signals to the patient. The microphone and speaker(s) are integrated with the cushion to avoid interfering with the comfort of the patient. In one embodiment, the audible signals are delivered to and from the patient via a communication port. In another embodiment, the system includes a display device, so the patient may view parts of the patient's body on the device and then communicate with system operators through the microphone and speaker(s).

Abstract: A method, system, and products that allow for accurate localization, virtual depiction, and testing of nerve(s) or neural structures that course through or around a proposed surgical site are described. The method and system employs a variety of types of neurodiagnostic tests that incorporate sensory, motor, and mixed nerve conduction studies in an orthodromic and antidromic fashion as well as utilizing triggered electromyography. This method, system, and products allow for a much more specific and sensitive method to assess the baseline function and continued integrity of nerves and neural structures prior to, during, and after a surgical procedure.

Abstract: A rehabilitation device is presented that is inexpensive to produce and is easy to use. The device uses a predictable method to estimate the activity of muscle and therefore provide many ways to train and rehabilitate a person having a prosthetic limb or other neuromuscular disorder.

Abstract: Methods and systems incorporating non-linear dynamic (NLD) analysis such as entropy or other complexity analysis monitoring continuous or evoked signals from a biological subject are presented, where such a system comprises of processing steps including: a) the combination of a biological signal evoked as a result of patient stimulation presented to a biological subject and a non-linear analysis method capable of capturing temporal changes in signal order or regularity; b) any combination of processed evoked or continuous central nervous or peripheral physiological mechanisms b) a means to generate a measure indicative of a patient's level of anaesthesia and consciousness depth (A&CD), sedation or sleep/wake state.

Abstract: A biofeedback system and a display device for the use in the biofeedback system. Also disclosed is a method for a biofeedback treatment of a person or an animal. Biofeedback is a therapy method which is used in rehabilitation facilities, for example in the neurological rehabilitation. A neural signal magnitude below a certain threshold does not result in a muscle response, for example, because the provided stimulus is insufficient to trigger the muscle. In order to provide a patient with an intuitive feedback of the sub-threshold neural signal nevertheless, the signal is detected and made recognizable to the patient.

Abstract: The present invention relates generally to an algorithm aimed at neurophysiology monitoring, and more particularly to an algorithm capable of quickly finding stimulation thresholds over multiple channels of a neurophysiology monitoring system.

Abstract: The present invention relates to a method and an apparatus for preventing, diagnosing, monitoring, and/or treating bruxism as well as related diseases of an individual. In a first aspect the invention relates to an apparatus for preventing bruxism of an individual, comprising: means for applying a plurality of stimulation signals for providing relaxation of at least one of the masticatory and/or facial muscles of said individual, means for applying said stimulations signals with a predefined setting, and means for applying said stimulations signals independent of activity of said muscle(s). The invention may be suitable for both nocturnal and awake bruxism.

Abstract: A system and method of acquiring and transmitting uterine EMG signals is disclosed, where a signal processing module processes incoming uterine EMG signals from a patient and wirelessly transmits a processed signal to an information relaying device. The information relaying device is then configured to download the processed signal and transmit the signal to a call center or health care facility for physician evaluation. The system is ambulatory, thus allowing the patient to record and transmit uterine EMG signals anywhere a satisfactory transmission may be made.

Abstract: Biometric assessment is performed by use of electromyography (EMG) signals detected from muscles at several locations on the hand/or other part of the body subject to fine motor control. The EMG signals are sensed and registered and the sensed signals are processed for use in performing the biometric assessment.

Abstract: A physiological measuring system is disclosed that monitors certain physiological parameters of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to calculating derivations of such parameters. A oxygen debt measuring embodiment is directed predicting an outcome in response to injury and illness. The technique allows for closed-loop resuscitation, early identification of illness and early corrective action.

Abstract: The present invention relates generally to muscle relaxation. Muscle relaxation is desired in many disease states, including spastic paresis and biomechanical and neuromuscular dysfunction. More specifically, the invention relates to a system that causes muscle relaxation by reducing muscular spasticity through the stimulation of joints and muscles. The system consists of a garment with electrodes, a hardware unit and software controlling the stimulation.

Abstract: A patient monitoring system to measure the depth of anesthesia, and to provide a physician warning during a surgical procedure.

Abstract: System (20) and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to determine nerve proximity and nerve direction to surgical instruments (30) employed in accessing a surgical target site.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

Abstract: An electronic device includes an upper layer made of a non-conductive material; a lower layer made of a non-conductive material, wherein at least one of the upper layer and the lower layer is made of a resilient material having a sufficient elasticity such that it will return to an original shape after being deformed, wherein the upper layer comprises an upper conductor and the lower layer comprises a lower conductor and a space is provided between the upper conductor and the lower conductor such that the upper conductor and the lower conductor are not in contact until a force is applied to deform at least one of the upper layer and the lower layer. A sensor device for human body testing connected with the lower conductor, or the lower conductor is configured to function as part of a sensor device for human body testing.

Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.

Abstract: The present invention is concerned with an electrode and electrode catheter using thin metallic threads or wires, for example, microwires having diameters as low as 10?6 to 10?4 meters or less. The embodiments allow for the efficient mounting of at least one electrode on a catheter, resulting in the creation of a flexible ring-microelectrode that is suitable for, amongst other things, the detection of myoelectrical activity in a patient's muscle, such as the diaphragm or other inspiratory-related muscle.

Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.

Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.

Abstract: The present invention involves systems and related methods for performing dynamic pedicle integrity assessments involving the use of neurophysiology.

Abstract: Among other things, at least two different independent providers of body composition management services are enabled to have online access through respective graphical user interfaces to body composition information and plans that are associated with respective clients of the providers and that are stored on the server. The graphical user interfaces are different for different independent providers. At least some of the information and plans associated with the clients of the different independent providers are stored in a common format in a common database maintained by the server.

Abstract: A system includes an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Abstract: An apparatus for processing signals, in particular physiological measuring signals, wherein the apparatus is provided with different channels with signal inputs (1) for receiving input signals, which input signals each comprise a specific signal component and a signal component common to all input signals, wherein each channel is provided with an impedance transforming input amplifier (3), wherein the apparatus is configured for supplying to the non-inverting input of each input amplifier (3) a respective input signal and, to the inverting input an analogue reference signal common to all channels, wherein the apparatus is provided with a digital signal processor (10) and one more or analogue-digital converters (5) for supplying the signals provided by the input amplifiers (3) to the digital signal processor (10), wherein the signal processor (10) is designed for converting the signals received from the one or more analogue digital converters (5) into one or more output signals.

Abstract: A classification estimating system can include an input element group; an intermediate element group into which are input values of first intermediate variables for which a first multiple desensitization, including an accumulation of values of each input element of a first input element group and each value of a first output sensitivity and each value of a first multiplex output sensitivity, has been carried out and calculated; an output element group into which is input a value of an output variable calculated based on a value of each intermediate element of a first intermediate element group and a value of each connection weight; a classification information estimating module for estimating classification information based on pre-stored correspondence relationship information and a value of the output variable; and a classification information display.

Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.

Abstract: Methods and systems for modifying or enhancing vision are described. In exemplary embodiments, neural or neuromuscular activity is analyzed to determine a focus or other quality of a visual input, and the focus or quality information used as a basis for controlling an adjustable lens system or optical system.

Abstract: Provided is a device for providing pressure to a body limb. The device includes an actuating unit configured to apply a varying pressure to a first region of the limb and a sensing unit monitoring a state of a second region of the limb and generating a time dependent signal indicative of the state of the second region of the limb. A processor analyzes the signal generated by the sensing unit and determines a time dependent state of the second region. The processor activates the actuating unit to generate a time dependent pressure on the first region of the body limb based upon the time dependent state of the second region.

Abstract: Apparatus for monitoring muscle activity, said apparatus comprising means for providing signals indicative of muscle activity, for example EMG-signals, means for processing of said signals in order to detect a particular activity and means for providing a feedback signal, wherein said device is designed in order to be individually adaptable in a set-up mode. The apparatus can be used for detecting and prevention of undesired activities such as bruxism, movements that are damaging or unwanted etc. The detection can be performed with great certainty since the individual parameters of the user are utilized for laying down reference values, threshold values, criteria for triggering of feedback signals, etc., which may take place at a set-up procedure.

Abstract: Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

Abstract: An exercise monitoring apparatus, system, and method are disclosed herein to reliably monitor an exercise using an inertial sensor and a electromyographic sensor. The sensed information may be used to determine a muscle fatigue associated with the exercised muscle and may reduce health risk factors associated with immoderate exercise. The exercise monitoring apparatus as embodied and broadly disclosed herein may include a communication unit adapted to receive muscle movement and electromyographic information from a physical information measuring apparatus. The exercise monitoring apparatus may further include a controller configured to acquire identification information related to the muscle, determine a type of exercise based upon the acquired identification information and the muscle movement related signal, and measure muscle fatigue based upon the type of exercise, the muscle movement related signal, and the electromyographic signal.

Abstract: Biometric assessment is performed by use of electromyography (EMG) signals detected from muscles at several locations on the hand/or other part of the body subject to fine motor control. In addition, electroencephalography (EEG), signals detect other biomarkers. The EMG and EEG signals are sensed, synchronized and registered. The signals are converted into digital data and are stored and processed for use in performing the biometric assessment.

Abstract: Disclosed is a muscle synergy analysis which comprises detecting a myoelectric signal generated at each muscle of an antagonistic muscle pair group of a subject; calculating, as time-series data, an antagonistic muscle ratio of an antagonistic muscle pair at a myoelectric signal level from a myoelectric signal detected during a predetermined motion by the subject; and conducting multi variate analysis using the antagonistic muscle ratio at each time of the time-series data as a variable to calculate a principal component including at least a first principal component having high contribution to correlation.

Abstract: A personal monitoring device has a sensor assembly configured to sense physiological signals upon contact with a user's skin. The sensor assembly produces electrical signals representing the sensed physiological signals. A converter assembly, integrated with, and electrically connected to the sensor assembly, converts the electrical signals generated by the sensor assembly to a frequency modulated inaudible ultrasonic sound signal. The ultrasonic signal is demodulated from an aliased signal produced by undersampling.

Abstract: A system and a method that promotes the restoration of physical functions of the neuromuscular system by incorporating into one device the treatment modalities of biofeedback based repetitive practice, includes an actuator, a joint position measurement system, a force sensing measurement system, an EMG measurement system, a neuromuscular low-level stimulation system, a controller, and a display device.

Abstract: Apparatus and methods for monitoring electrical activity within the brain of a person (“brainwaves”) employing electrodes or other sensors connected or placed proximate to portions of the body below the head to develop raw signals. The raw signals are filtered to produce analysis signals including frequency components relevant to brain electrical activity while attenuating unrelated frequency components. Purposes include but are not limited to, biofeedback-based attention training, human performance training, gaming, and relaxation training. Either wired or wireless signal connections are made to electronic circuitry, typically including a digital computer, for performing signal processing and analysis functions.

Abstract: An electrode arrangement is described for sensing electrical activity in target tissue. An inner electrode has an elongate electrode body formed as a cylindrical section with an inner penetrating end for insertion into the stapedius muscle target tissue. An outer electrode fits over the inner electrode and an outer penetrating end for insertion into the target tissue. The two electrodes are joined together with their electrode bodies in parallel so that the penetrating ends of the electrodes penetrate in the same direction into the target tissue to sense electrical activity in the target tissue.

Abstract: A process is provided for manufacturing a multielectrode that may be used to record a bioelectrical potential difference at a detection site. The manufacturing process may comprise manufacturing a carrier from multiple thin layers of an insulating material. The manufacturing process may further comprise providing at least one recording electrode of a set of electrode pairs on at least one of the layers of the carrier. Each recording pair may include one active electrode surface and a different reference electrode surface. Also, the manufacturing process may further comprise folding, fastening, and gluing the layers of the insulating material to one another.

Abstract: An apparatus and method for detecting uterine activity uses cutaneous electrodes on the maternal abdomen to obtain electrophysiological signals that can be used to obtain fetal and maternal heart rate. The apparatus includes a first input for receiving electrical signals from the cutaneous electrodes and a second input for receiving movement signals indicative of a movement of the maternal body from a movement detector. A signal processor separates a uterine electromyogram signal from fetal and maternal heart rate signals and filters out motion artefacts from the electromyogram using the movement signals. An output presents electrohysterogram (EHG) data from the uterine electromyogram signal.

Abstract: A measurement device (10) for quantitatively measuring stiffness, torque or range of motion (ROM) around the joint axis of the ankle-foot complex of a lower limb in the sagittal and coronal planes, the device (10) comprising: a plate (13, 21) for placement of the ankle-foot complex, the plate (13, 21) operatively connected to an actuator (14, 16) for manual actuation; an angular measurement device (12, 17) to measure an angular position of the ankle-foot complex; a torquemeter (11) to measure resistance torque of the ankle-foot complex; an electromyograph (48) to monitor muscular activity of muscles of the lower limb; and computer software to record the measured angular position, resistance torque of the ankle-foot complex and EMG of the lower limb muscles.

Abstract: A muscular function monitoring and evaluating system includes a processor, a wireless interface, a display, a storage device storing a program and sets of test procedures, a signal collection device wirelessly coupled to the processor and a sensor connected to the signal collection device. The program, when executed by the processor, causes the system to display a patient information screen on the display for an operator to input patient's data of a patient to be tested, and receive the patient's data input through the screen. The processor displays, in accordance with one of the sets of test procedures, a muscle map indicating a place on the patient's body to which the sensor is to be attached. The processor instructs the patient through displayed instruction language, an animation or video image, or audible instructions.

Abstract: An apparatus for monitoring the activity of a surgeon. At least one wireless sensing unit is provided for monitoring potential damage to a nerve and is located at a first location of a body being operated on by a surgeon. The wireless sensing unit senses a change in the body at the first location resulting from potential damage to the nerve occurring at a second location of the body remote from the first location. The wireless sensing unit produces a wireless sensed change output signal indicative of the change in the body which is received by a receiver and generates a corresponding received output signal. An analyzer unit receives and analyzes the received output signal to determine the change in the body. An indicator responsive to the output of said analyzer unit indicates the change in the body to indicate the potential damage to the nerve the surgeon.

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

Abstract: Systems and methods for sleep state classification involve detecting conditions related to sleep, including at least one condition associated with rapid eye movement (REM) sleep. Additionally, a condition modulated by the sleep-wake status of the patient may be detected. A medical system that is partially or fully implantable incorporates sensors and circuitry for detecting and processing the sleep-related signals. A sleep state processor classifies the patient's sleep state based on the sleep-related signals. Sleep state classification may be used in connection with the delivery of sleep state appropriate therapy, diagnostic testing, or patient monitoring.

Abstract: A device for continuous, uninterrupted patient monitoring includes a portable, self-contained Patient Worn Hub (PWH) device. The PWH is a compact, lightweight patient monitoring device designed to remain with the patient for the duration of care. Parameter measurement devices connect to the PWH. Third party parameter measurement devices connect to the PWH via the use of a connection assembly that translates the information provided by the third party device to the protocol embedded within the PWH. The PWH is able to communicate with a bedside monitor via wired cables or wirelessly. Measured values are shown on external displays and/or on an optional integrated PWH touchscreen display. The PWH includes internal memory for storage of patient data and trends. The PWH optionally includes a docking station for providing operating and battery charging power.

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

Abstract: Electrodes of a subcutaneous monitoring system receive body electrical signals that indicate both cardiac and non-cardiac muscle activity. In general, non-cardiac muscle activity is often correlated with physical activity, and physical activity is typically a strong indicator of patient health. Exemplary systems and methods that detect non-cardiac muscle activity information in sensed body electrical waveforms may provide a diagnostic tool for monitoring physical activity level over time in patients that have subcutaneous monitoring systems. In an illustrative embodiment, systems and methods for presenting patient activity information in a graphical format over intervals of time include processing ECG waveform information to identify and to accumulate non-cardiac muscular activity information during each of the intervals of time. In various implementations, number, intensity, and/or duration of the events that are identified during a time interval may be accumulated and stored for subsequent recall.

Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.

Abstract: A method of detecting seizures may comprise receiving an EMG signal and processing the received EMG signal to determine whether a seizure characteristic is present in the EMG signal during a time window. An apparatus for detecting seizures with motor manifestations may comprise one or more EMG electrodes capable of providing an EMG signal substantially representing seizure-related muscle activity; and a processor configured to receive the EMG signal, process the EMG signal to determine whether a seizure may be occurring, and generate an alert if a seizure is determined to be occurring based on the EMG signal.

Abstract: Apparatus is disclosed for monitoring strain and/or load applied to the body of a vertebral mammal. The apparatus includes means (10, 11) for measuring position of the body relative to an inertial frame of reference and for providing first data indicative of the position, wherein the means for measuring position includes at least one inertial sensor such as an accelerometer. The apparatus includes means (12, 15-19) for measuring muscle activity and for providing second data indicative of the muscle activity. The apparatus also includes means for storing the data and means for processing the data to provide a measure of strain and/or load to the body. The strain and/or load is typically applied to the back of the mammal. A method of monitoring strain and/or load applied to the body of the vertebral mammal is also disclosed.