Sensitivity To Electric Stimulus Patents (Class 600/554)
  • Patent number: 10376208
    Abstract: A nerve mapping system includes a plurality of electrodes, a sensor, and a processor in communication with each of the plurality of electrodes and the sensor. Each electrode is disposed on the distal end portion of one or more elongate medical devices configured to extend within an intracorporeal treatment area of a subject. The sensor is in communication with a muscle of a subject, and is configured to provide an output signal corresponding to a monitored response of the muscle. The processor receives an indication of the location of each electrode and an indication of a magnitude of the monitored muscular response. Using these parameters, the processor determines a distance to the nerve from the location of each of the plurality of electrodes, and constructs a virtual model of the nerve using the determined distance to the nerve at each of the plurality of locations.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: August 13, 2019
    Assignee: Innovative Surgical Solutions, LLC
    Inventor: Christopher Wybo
  • Patent number: 10376209
    Abstract: A method of locating a nerve within an intracorporeal space includes advancing a distal end portion of a stimulator toward an anatomical target within the intracorporeal space, and periodically applying a first electrical stimulus from a first electrode disposed on a central axis of the stimulator. If a muscular response to the first electrical stimulus is detected, a locating electrical stimulus is then applied from a plurality of locations offset from the central axis of the stimulator, and a magnitude of the response of the muscle is monitored. A distance between the nerve and each of the plurality of locations is determined from the magnitude of the muscular response, and from a magnitude of the locating electrical stimulus provided at each of the plurality of locations. The location of the nerve is then triangulated from the determined distance at each of the plurality of locations.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: August 13, 2019
    Assignee: Innovative Surgical Solutions, LLC
    Inventor: Christopher Wybo
  • Patent number: 10321833
    Abstract: A method of locating a nerve within an intracorporeal treatment area of a subject includes providing a first electrical stimulus at a first location within the intracorporeal treatment area, providing a second electrical stimulus at a second location within the intracorporeal treatment area, and providing one or more additional electrical stimuli at the second location. The first electrical stimulus does not induce a threshold response of a muscle innervated by the nerve, whereas the second electrical stimulus does induce a response of the muscle. The one or more additional stimuli each have a current magnitude less than the first stimulus and are used to determine a minimum current magnitude that is required to induce the threshold response of the muscle at the second location. This minimum current magnitude is then used to determine a distance from the second location to the nerve.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: June 18, 2019
    Assignee: Innovative Surgical Solutions.
    Inventor: Christopher Wybo
  • Patent number: 10307593
    Abstract: A neuromodulation system executes a set of startup operations. In response to completion of the startup operations, a priming field is automatically initiated. The priming field is to produce a priming effect in priming-targeted neural tissue, with the priming effect causing a change in sensitization to a therapeutic neuromodulation field of the priming-targeted neural tissue. The system also generates the therapeutic neuromodulation field to produce a therapeutic effect in therapy-targeted neural tissue.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: June 4, 2019
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Que T. Doan, Bradley Lawrence Hershey, Changfang Zhu
  • Patent number: 10278600
    Abstract: A method for measuring a neural response to a stimulus. Measurement circuitry is settled prior to a stimulus, by connecting a sense electrode to the measurement circuitry to allow the measurement circuitry to settle towards a bio-electrically defined steady state. Charge is recovered on stimulus electrodes by short circuiting the stimulus electrodes to each other. An electrical stimulus is then applied from the stimulus electrodes to neural tissue, while keeping the sense electrode disconnected from the measurement circuitry. After the stimulus, a delay is imposed during which the stimulus electrodes are open circuited and the sense electrode is disconnected from the measurement circuitry and from the stimulus electrodes. After the delay, a neural response signal present at the sense electrode is measured by connecting the sense electrode to the measurement circuitry.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: May 7, 2019
    Assignee: Saluda Medical Pty Ltd.
    Inventors: John Louis Parker, Peter Scott Vallack Single, Dean Michael Karantonis
  • Patent number: 10255527
    Abstract: The present disclosure is directed toward systems and methods that enable more accurate digital object classification. In particular, disclosed systems and methods address inaccuracies in digital object classification introduced by variations in classification scores. Specifically, in one or more embodiments, disclosed systems and methods generate probability functions utilizing digital test objects and transform classifications scores into normalized classification scores utilizing probability functions. Disclosed systems and methods utilize normalized classification scores to more accurately classify and identify digital objects in a variety of applications.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: April 9, 2019
    Assignee: DROPBOX, INC.
    Inventors: David J. Kriegman, Peter N. Belhumeur, Thomas Berg, Nils Peter Welinder
  • Patent number: 10238312
    Abstract: Provided is a wrist-type body component measuring apparatus. The wrist-type body component measuring apparatus includes: a band configured to be worn on a wrist of a user; a first input electrode and a first output electrode disposed on an inside surface of the band and configured to be in contact with the wrist of the user; a second input electrode and a second output electrode disposed on an outside surface of the band; a measuring unit configured to apply a current to the first and second input electrodes and detect a voltage from the first and second output electrodes to measure a body impedance of the user; and an electrode converter configured to convert a disposition of the first and second input electrodes and the first and second output electrodes based on a determination of whether the band is worn on a left wrist or a right wrist of the user.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: March 26, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kunsun Eom, Yeolho Lee, Kak Namkoong, Myounghoon Jung, Seongho Cho
  • Patent number: 10231666
    Abstract: Device and method for determining an efficacy of chronic pain treatment including providing a first set of at least one stimulus to a subject, obtaining first measurements of at least two physiological parameters in response to the first set of at least one stimulus, providing chronic pain treatment to the subject, providing a second set of at least one stimulus to the subject, obtaining second measurements of the at least two physiological parameters in response to the second set of at least one stimulus; and determining an efficacy of the chronic pain treatment by applying a classification algorithm on the first and second measurements of the at least two physiological parameters.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: March 19, 2019
    Assignee: Medasense Biometrics Ltd.
    Inventors: Galit Zuckerman-Stark, Noam Racheli, Nir Ben-Israel
  • Patent number: 10226627
    Abstract: An example a system includes a neuromodulation generator that may be configured to use electrodes to generate a first modulation field over a test region of neural tissue along the electrodes to prime the neural tissue throughout the test region and a second modulation field to test targeted locations within the test region for therapeutic effectiveness. A memory may be configured to store a first modulation field parameter for generating the first modulation field and a second modulation field parameter set for generating the second modulation field to modulate a targeted location within the test region. The second modulation field parameter set is programmable for modulating other targeted locations. The controller may be configured to control the neuromodulation generator to use the first modulation field parameter set to deliver the first modulation field and to use the second modulation field parameter set to deliver the second modulation field.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: March 12, 2019
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Que T. Doan, Bradley Lawrence Hershey, Changfang Zhu
  • Patent number: 10111708
    Abstract: System and method for locating and identifying nerves innervating the wall of arteries such as the renal artery are disclosed. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The method includes at least the steps to evaluate a change in physiological parameters after energy is delivered to an arterial wall; and to determine the type of nerve that the energy was directed to (none, sympathetic or parasympathetic) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: October 30, 2018
    Assignee: SYMAP MEDICAL (SUZHOU), LTD
    Inventor: Jie Wang
  • Patent number: 10098585
    Abstract: Systems, devices and methods are provided for neuromonitoring, particularly neuromonitoring to reduce the risks of contacting or damaging nerves or causing patient discomfort during and after surgical procedures, including spinal surgeries. The neuromonitoring procedures include monitoring for the presence of or damage to sensory nerves, and optionally includes additional monitoring for motor nerves. In some systems, including systems that monitor for both sensory and motor nerves, components of the monitoring systems (e.g., stimulating electrodes and response sensors), may be combined with one or more surgical instruments. The systems, devices, and methods provide for pre-surgical assessment of neural anatomy and surgical planning, intraoperative monitoring of nerve condition, and post-operative assessment of nerve position and health.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: October 16, 2018
    Assignee: Cadwell Laboratories, Inc.
    Inventors: Justin Scott, John Cadwell
  • Patent number: 10046160
    Abstract: Disclosed is a method for treating dermis and hypodermis by placing at least a first electrode at the surface of a to-be-treated skin region and contacting a second electrode at another position on the body to be treated then applying between the electrodes a current with pulse component, said current being sufficient to produce electro-osmotic pressure/velocity wavefronts corresponding to the fundamental frequency in blood vessels in the dermis and hypodermis of the skin region.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: August 14, 2018
    Assignee: NSE Products, Inc.
    Inventor: Dale G. Kern
  • Patent number: 10045714
    Abstract: The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro-stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: August 14, 2018
    Assignees: RGB Medical Devices S.A., Fundació Eurecat
    Inventors: José Javier Rodiera Olivé, Antonio González Martínez, Francisco Javier Corral Herranz, Ricardo Ruiz Nolasco
  • Patent number: 10004445
    Abstract: The invention relates to apparatus and methods for stimulating living tissues to determine nerve conduction properties using a pair of stimulator probes and a plurality of detection electrodes. The invention overcomes the problem of reporting potentially inaccurate nerve conduction results by detecting a stimulator probe short or shunt condition during nerve conduction tests. Detection of a short or shunt condition between two stimulator probes is accomplished by monitoring the magnitude of the stimulus artifact waveform acquired from the detection electrodes and the voltage difference between the stimulator probes. A test is flagged when magnitude of the stimulus artifact waveform is below a first threshold and voltage difference between the two stimulator probes is below a second threshold. The first and second threshold values are determined based on the known spatial relationship between the stimulator probes and detection electrodes. Feedback is provided to the tester to alert defective test conditions.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: June 26, 2018
    Assignee: NeuroMetrix, Inc.
    Inventors: Bonniejean Boettcher, Glenn Herb, Xuan Kong
  • Patent number: 9999766
    Abstract: A device and method verifies the electrical output of a microcurrent therapy device. The current and/or voltage of an electrical pulse, being supplied to an electrode adapted to contact tissue, is measured by a control unit. The current and/or voltage is supplied by the control unit according to a predefined waveform. Any difference in the current or voltage of the electrical pulse being supplied with respect to the current or voltage of the predefined waveform is detected.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: June 19, 2018
    Assignee: Synapse Electroceutical Limited
    Inventor: Charles Richard Elliott
  • Patent number: 9949651
    Abstract: A surgical system kit is described. The surgical system kit includes a peripheral electrode, a surgical access instrument configured to be placed in a surgical target site, and a control unit. The surgical access instrument has a body with a proximal end, and a distal end, two or more electrodes on the distal end at fixed locations and spaced apart a known distance. The control unit is configured to send a signal to the peripheral electrode, receive information indicative of a neural response from at least one electrode of the surgical access instrument, and interpret the information according to a nerve conduction velocity modality to measure the nerve conduction velocity through the segment of the nerve.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: April 24, 2018
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Corbett Stone, Robin Vaughan, Kabir Gambhir
  • Patent number: 9936889
    Abstract: A method of controlling a threshold for detecting peaks of physiological signals includes: obtaining a physiological signal measured from a person being examined; determining whether a peak of the physiological signals is detected based on a result of comparing the physiological signals with a threshold; and controlling the threshold based on a minimum threshold and either the threshold or a feature value of the detected peak based on a result of the determining. When a threshold for detecting peaks of physiological signals is controlled, even if an interval between the peaks is irregular or there is a large difference in values of the peaks, the peaks can be accurately detected.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: April 10, 2018
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Chang-mok Choi, Youn-ho Kim, Kun-soo Shin
  • Patent number: 9931077
    Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: April 3, 2018
    Assignee: NuVasive, Inc.
    Inventors: Norbert F. Kaula, Jeffrey J. Blewett, James Gharib, Allen Farquhar
  • Patent number: 9919152
    Abstract: Systems and methods for gastrointestinal electrical stimulation to treat abnormalities in gastrointestinal motility are provided. In some embodiments, a system for relieving ileus includes an intraluminal catheter comprising: a catheter body having a proximal tip and a distal tip and a duodenal portion proximal to the distal tip of the catheter; and at least one electrode pair disposed along the duodenal portion of the intraluminal catheter, the at least one electrode pair being configured to detect a sensing information indicative of myoelectric activity of a patient and to provide stimulation energy; a sensing system in communication with the at least one electrode pair to receive the sensing information; and an energy delivery system in communication with the at least one electrode pair and the sensing system, the electrical energy delivery system being configured to delivery energy to the patient through the at least one second electrode pair based on the sensing information from the sensing system.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: March 20, 2018
    Assignee: Enterastim, Inc.
    Inventors: Andy H. Levine, Michael Partsch, Jay Pasricha, Jiande Chen
  • Patent number: 9846822
    Abstract: The present disclosure is directed toward systems and methods that enable more accurate digital object classification. In particular, disclosed systems and methods address inaccuracies in digital object classification introduced by variations in classification scores. Specifically, in one or more embodiments, disclosed systems and methods generate probability functions utilizing digital test objects and transform classifications scores into normalized classification scores utilizing probability functions. Disclosed systems and methods utilize normalized classification scores to more accurately classify and identify digital objects in a variety of applications.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: December 19, 2017
    Assignee: DROPBOX, INC.
    Inventors: David J. Kriegman, Peter N. Belhumeur, Thomas Berg, Nils Peter Welinder
  • Patent number: 9814858
    Abstract: Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic. Methods for use of this apparatus are also described.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: November 14, 2017
    Assignee: Avent, Inc.
    Inventor: Michael F. Guzman
  • Patent number: 9808208
    Abstract: A device, system and method for monitoring carpal tunnel syndrome (“CTS”). The device comprises a body configured to be worn by a user, sensors, a processor, a vibration mechanism, and a power source. The sensors monitor a position of the user's hand to prevent CTS. The processor of the device is configured to determine if the user's hand is in a CTS position and the processor is configured to generate an alert signal to alert the user to the CTS position.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: November 7, 2017
    Assignee: Focal Wellness, Inc.
    Inventor: Randal Erman
  • Patent number: 9764128
    Abstract: A method of identifying a location for applying a stimulation therapy to treat a patient includes stimulating a first body region of the patient transcutaneously via a stimulus generator. The body region contains a first portion of a nerve that has an elongate shape. In response to the stimulating, action potentials received from a second portion of the nerve are monitored over a period of time. The second portion of the nerve is in a second body region of the patient that is located remotely from the first body region. Based on the monitoring, an optimized location of the second portion of the nerve is determined for applying the stimulation therapy to treat the first body region.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: September 19, 2017
    Assignee: Greatbatch, LTD.
    Inventors: Kerry Bradley, Leslie Halberg
  • Patent number: 9743884
    Abstract: One embodiment includes a method for monitoring nerve tissue which includes inserting a dilator into muscle, the dilator including first and second electrodes at the distal tip. While the dilator is in muscle, a system may communicate (a) a first series of unequal current amplitude applications (e.g., a series including 0.5, 7, 3, 5 mA applications) to the first electrode to produce at least a first evoked potential (e.g., a MAP or NAP), and (b) a second series of unequal current amplitude applications to the second electrode to produce at least a second evoked potential. The method further includes sensing the first and second evoked potentials and determining a relative location of a nerve based on the sensing of at least one of the first and second evoked potentials.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: August 29, 2017
    Assignee: J3G Spine, LLC
    Inventor: Jann Rasmussen
  • Patent number: 9743845
    Abstract: This invention provides methods for mapping and ablating renal nerves to treat disease caused by systemic renal nerve hyperactivity, e.g. hypertension, heart failure, renal failure and diabetes. Also provided are catheters for performing the mapping and ablating functions.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: August 29, 2017
    Assignee: SYMAP MEDICAL (SUZHOU), LTD
    Inventor: Jie Wang
  • Patent number: 9743921
    Abstract: A method for treating a spine includes disposing a body including vertebrae in a lateral orientation relative to a surgical fixed surface configured for supporting the body; creating an incision in tissue of the body along a substantially transverse plane of the body; spacing the tissue adjacent the incision along a sagittal plane of the body to define a surgical pathway to the vertebrae; and delivering at least one implant adjacent the vertebrae via the surgical pathway. Systems and implants are disclosed.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 29, 2017
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Michelle M. Hennard, Larry T. McBride, Jr.
  • Patent number: 9730634
    Abstract: An apparatus, system, and method are disclosed for mapping the location of a nerve. The apparatus includes at least one stimulation module, a stimulation detection module, a distance module, and a mapping module. The stimulation module stimulates a nerve with an electrical stimulation current from at least one stimulation electrode. A stimulation detection module detects a muscle reaction resulting from stimulation of the nerve by the at least one stimulation electrode. The distance module uses information from the at least one stimulation electrode and from the stimulation detection module to calculate a distance between the at least one stimulation electrode and the nerve. The mapping module maps a location on the nerve using at least two distances calculated by the distance module and position information of the at least one stimulation electrode for each of the at least two distances calculated.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 15, 2017
    Assignee: Cadwell Labs
    Inventor: John Cadwell
  • Patent number: 9636140
    Abstract: A surgical scalpel, scalpel instrument and/or scalpel system (collectively, scalpel), is configured for use in a transverse carpal ligament surgical procedure. The scalpel evaluates an incision path with respect to a nerve in the incision path, and performs the incision if appropriate. The scalpel emits a signal through a potential incision path through tissue captured by the scalpel. The scalpel utilizes the emitted signal to determine whether a nerve is in the incision path. The surgical instrument includes a retractable blade. Evaluation includes determining whether a nerve is present before incision and/or evaluating whether the target tissue has been appropriately captured. A warning is provided when a nerve is in the incision path and/or the captured target tissue is inappropriate. The surgical instrument disables extension of the blade when a nerve is in the dissection path and/or the captured target tissue is inappropriate.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: May 2, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Conrad Lee Klotz, Sarah Elizabeth Stephens
  • Patent number: 9636239
    Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: May 2, 2017
    Assignee: Case Western Reserve University
    Inventors: Dominique M. Durand, Brian Wodlinger
  • Patent number: 9622684
    Abstract: A neural monitoring system includes an elongate medical instrument, a non-invasive mechanical sensor, and a processor. The elongate medical instrument has a distal end portion configured to extend within an intracorporeal treatment area of a subject, and a plurality of electrodes disposed on the distal end portion. Each electrode is respectively configured to provide an electrical stimulus. The non-invasive mechanical sensor is configured to be placed in mechanical communication with a muscle of the subject and to generate a mechanomyography output signal corresponding to a sensed mechanical movement of the muscle. The processor is provided in communication with the elongate medical instrument and the mechanical sensor, and is configured to receive the mechanomyography output signal, and determine a relative direction between a nerve and the distal end portion of the elongate medical instrument using the received mechanomyography output signal.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: April 18, 2017
    Assignee: Innovative Surgical Solutions, LLC
    Inventor: Christopher Wybo
  • Patent number: 9585618
    Abstract: Technologies are generally provided for identifying and marking the location of the laryngeal nerve prior to tissue dissection. A frame may include two multi-electrode stimulating probes, a slider with a guide movable between the two probes, and a marker probe including an anchor. The two probes supported on the frame may be inserted into tissue in a vicinity of the nerve, and a controller may sequentially stimulate the electrodes on each probe and measure electromyography (EMG) responses from each stimulated electrode. The controller may determine the nerve's location relative to the probes based on the measured EMG responses, where the location may include a lateral position between the probes and an estimated depth. The slider may be moved to the lateral position and the marker probe may be inserted through the slider to the determined depth. The anchor may be deployed next to the nerve to indicate the nerve location.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: March 7, 2017
    Assignee: EMPIRE TECHNOLOGY DEVELOPMENT LLC
    Inventors: Boris Leschinsky, Jonathan R. Williams
  • Patent number: 9579037
    Abstract: A nerve monitoring system facilitates monitoring an integrity of a nerve.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: February 28, 2017
    Assignee: Medtronic Xomed, Inc.
    Inventors: William C. Brunnett, David C. Hacker, John A. Meyer, Kevin Lee McFarlin, John Murdock Murphy, Dwayne S. Yamasaki, John N. Gardi
  • Patent number: 9572633
    Abstract: An instrument holder includes a substantially tubular base body which includes a grip portion and an instrument holding portion. The base body includes a through recess extending over an entire length thereof, and the instrument holding portion includes a front-sided insertion opening designed for insertion of an instrument.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: February 21, 2017
    Assignee: Gebr. Brasseler GmbH & Co. KG
    Inventors: Michael Krumsiek, Stefan Tuenker, Stefan Neumeyer
  • Patent number: 9554713
    Abstract: A muscle stimulator that may be used during ARM surgeries is disclosed that may be constructed from (1) a widely available low cost (e.g., $200 per unit) peripheral nerve stimulators or similar stimulator and (2) a relatively simple, handheld surgical probe to provide a low cost muscle stimulator that is adequate for ARM surgeries. These two components could provide a low cost solution to allow doctors in developing countries feasibly perform ARM surgeries with relatively minimal manufacturing and inexpensive maintenance.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: January 31, 2017
    Assignee: Global Pediatric Surgical Technology and Education Project, Inc.
    Inventors: Philip Kent Frykman, Keith J. Kimble
  • Patent number: 9539145
    Abstract: Systems and techniques for providing data to a user in the form of perceived light signals caused by transcutaneous stimulation of the user's optic nerve. User output data, suitably representing data collected, generated, or processed by a data processing device, is used to generate user output data. The user output data is converted to representations corresponding to light signals, and control functions are performed to cause generation of electrical impulses which, when applied to the skin of a user, stimulate the optic nerve of the user so as to cause the user to perceive the light signals.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: January 10, 2017
    Assignee: Nokia Technologies Oy
    Inventors: Akos Vetek, Jari Kangas, Leo Karkkainen, Tatiana G. Evreinova, Grigori E. Evreinov
  • Patent number: 9427224
    Abstract: Apparatus, systems, and methods are provided for performing assessments while doing surgery using evoked potential somatosensory and/or magnetic field induction to determine the proximity and/or location of nerves relative to surgical instruments when accessing a surgical target site.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: August 30, 2016
    Inventor: Dhiraj Jeyanandarajan
  • Patent number: 9427580
    Abstract: An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device such that the stimulus device applies said electrical stimulus in response to a detected ingestion of food.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: August 30, 2016
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Toralf Bork, Rocco Crivelli, Mathilde Miguras, Martin Pfleiderer, Yanik Tardy, Jason L. Harris, Mark S. Ortiz, Alessandro Pastorelli, Michele D'Arcangelo
  • Patent number: 9399135
    Abstract: An electronic stimulator device comprises a battery, first and second output ports, and an energy discharge circuit. The energy discharge circuit is coupled to the battery and configured to receive an electrical charge from the battery and deliver the electrical charge through an energy output port. A first switch is connected between the energy output and the first output port. A second switch is connected between the second output port and electrical ground. A third switch is connected between the second output port and the energy output. A fourth switch is connected between the first output port and electrical ground. A controller comprising a processor is configured to actuate the first, second, third and fourth switches between open and close states to deliver a biphasic current pulse between the first and second output ports.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: July 26, 2016
    Assignee: Astora Women's Health, LLC
    Inventor: Jeffrey J. Childs
  • Patent number: 9386934
    Abstract: A method for measuring a neural response to a stimulus. Measurement circuitry is settled prior to a stimulus, by connecting a sense electrode to the measurement circuitry to allow the measurement circuitry to settle towards a bio-electrically defined steady state. Charge is recovered on stimulus electrodes by short circuiting the stimulus electrodes to each other. An electrical stimulus is then applied from the stimulus electrodes to neural tissue, while keeping the sense electrode disconnected from the measurement circuitry. After the stimulus, a delay is imposed during which the stimulus electrodes are open circuited and the sense electrode is disconnected from the measurement circuitry and from the stimulus electrodes. After the delay, a neural response signal present at the sense electrode is measured by connecting the sense electrode to the measurement circuitry.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: July 12, 2016
    Assignee: Saluda Medical Pty Ltd.
    Inventors: John Louis Parker, Peter Scott Vallack Single, Dean Michael Karantonis
  • Patent number: 9295576
    Abstract: A method for tuning an orthosis for the correct stiffness and/or shank angle includes via one or more computers, receiving patient information including forces experienced by a joint of a patient wearing an orthosis, wherein the orthosis has a degree of stiffness and a shank angle, via one or more computers, comparing the patient information to model information, wherein the model information includes the forces of a correctly functioning joint, and changing the degree of stiffness and/or the shank angle of the orthosis.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: March 29, 2016
    Assignee: Orthocare Innovations LLC
    Inventors: David Alan Boone, Toshiki Kobayashi
  • Patent number: 9295401
    Abstract: Systems, devices, and methods are described for neuromonitoring. A minimum stimulus signal required to elicit a threshold neuromuscular response is determined by delivery of stimulus signals to tissue and detection of neuromuscular responses in muscle tissue. The strength of the delivered stimulus signals is varied, for example by adjusting the current amplitude or pulse width of the signals, and muscle responses are measure, for example by detecting EMG signals. The delivered stimuli and corresponding responses are then used to determine a stimulation threshold. The stimulation threshold may be used to indicate at least one of nerve proximity and pedicle integrity.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: March 29, 2016
    Assignee: CADWELL LABORATORIES, INC.
    Inventor: John Cadwell
  • Patent number: 9259164
    Abstract: A peripheral nervous system (PNS) neuromuscular disorder testing system incorporates a testing apparatus that is affixed to a patients skin, positioning a stimulus transducer (e.g., electrical contact(s), movable sharp point, etc.) into a nerve pathway of interest with an electrode and reference electrodes appropriately positioned relative thereto to measure the electrical signal produced. A wireless connection to a control box relays the data associated with the time of the stimulus and the sensed response to a diagnostic system that analyzes the waveform per selectable testing protocols with user tailorable view capabilities and data dissemination communication paths.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: February 16, 2016
    Assignee: Neuronetrix, Inc.
    Inventor: Kalford C. Fadem
  • Patent number: 9241652
    Abstract: An auditory event-related potential measurement system includes: a video output section configured to present a video to a user; a measurement section configured to measure a user's electroencephalogram signal; a scheduling section configured to schedule a timing of presenting an auditory stimulation so that the auditory stimulation is presented during a period in which the video is being presented to the user; an auditory stimulation output section configured to present the auditory stimulation to the user at the scheduled timing; and a processing section configured to acquire, from the electroencephalogram signal, an event-related potential in a first time range as reckoned from a point in time at which the auditory stimulation is presented. When an amount of video luminance change exceeds a threshold value, the auditory stimulation is not presented during a second time range as reckoned from a point in time at which the threshold value is exceeded.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: January 26, 2016
    Assignee: Panasonic Intellectual Property Management Co., Ltd.
    Inventors: Shinobu Adachi, Jun Ozawa
  • Patent number: 9232906
    Abstract: An electromagnetic pedicle awl utilizes a tightly focused time-varying magnetic flux to create a localized electromotive force (EMF) near the tip. The localized EMF creates localized eddy currents in nearby nerves which excite ionic nerve channels, the excitation being detected by an electromyographic recording device. The awl only excites nerves directly in front of and directly to the side of the tip. The awl is comprised of a tapered awl or drill tip in combination with a solid core surrounded by a solenoid. A pulsed electric current source drives the solenoid to create a time-varying magnetic field in the vicinity of the tapered tip. The awl or drill tip may be stationary with respect to the solenoid or it may rotate. The awl in combination with an EMG detector connected to a patient is sensitive to the pedicle hole position with respect to adjacent nerves and reduces false placement failure.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: January 12, 2016
    Inventor: Erich Wolf, II
  • Patent number: 9211074
    Abstract: An automated system, method, apparatus, device and/or computer program product for detecting positioning effect is set forth, the apparatus according to an exemplary embodiment may include an output operable to couple to one or more stimulating electrodes to stimulate one or more peripheral nerves of the patient, an input operable to couple to one or more recording electrodes to record resultant electrical waveforms generated by a nervous system of a patient in response to the stimulating module, and one or more processors operable to identify the positioning effect based on the resultant electrical waveforms.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: December 15, 2015
    Assignee: SAFEOP SURGICAL, INC.
    Inventors: Samuel Johnson, Richard A. O'Brien
  • Patent number: 9162070
    Abstract: Provided is an electrical system including an intelligent learning terminal to analyze biometric information associated with a user and calculate an intensity of electrical stimulation for the user based on a result of the analyzing, and at least one wireless electrical stimulator to provide electrical stimulation to the user based on the calculated intensity of electrical stimulation, wherein the intelligent learning terminal is connected to the at least one wireless electrical stimulator based on wired or wireless communication.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: October 20, 2015
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Mi Seon Kang, Hyun Woo Kang, Yun Su Chung
  • Patent number: 9155503
    Abstract: An apparatus, system, and method are disclosed for mapping the location of a nerve. The apparatus includes at least one stimulation module, a stimulation detection module, a distance module, and a mapping module. The stimulation module stimulates a nerve with an electrical stimulation current from at least one stimulation electrode. A stimulation detection module detects a muscle reaction resulting from stimulation of the nerve by the at least one stimulation electrode. The distance module uses information from the at least one stimulation electrode and from the stimulation detection module to calculate a distance between the at least one stimulation electrode and the nerve. The mapping module maps a location on the nerve using at least two distances calculated by the distance module and position information of the at least one stimulation electrode for each of the at least two distances calculated.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 13, 2015
    Assignee: Cadwell Labs
    Inventor: John Cadwell
  • Patent number: 9147157
    Abstract: Certain aspects of the present disclosure provide methods and apparatus for identifying spectral peaks in a neuronal spiking representation of a signal, such as an auditory signal. One example method generally includes receiving a signal; filtering the signal into a plurality of channels using a plurality of filters having different frequency passbands; sending the filtered signal in each of the channels to a first type of spiking neuron model; sending the filtered signal in each of the channels to a second type of spiking neuron model; and identifying one or more spectral peaks in the signal based on a first output of the first type of spiking neuron model and a second output of the second type of spiking neuron model for each of the channels.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: September 29, 2015
    Assignee: QUALCOMM Incorporated
    Inventor: Michael Campos
  • Patent number: 9131947
    Abstract: Neurophysiological instruments and techniques are improved through various enhancements. Stimulation of an instrument is possible while it is advancing into the spine or elsewhere, alerting the surgeon to the first sign the instrument or device (screw) may be too near a nerve. A directional probe helps surgeons determine the location of the hole in the pedicle. Electrically insulating sleeves prevent shunting into the soft tissues. According to a different improvement, the same probe to be used to stimulate different devices, such as screws and wires. Electrical impulses may be recorded from non-muscle regions of the body, including the spine and other portions of the central nervous system as opposed to just the extremities.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: September 15, 2015
    Assignee: NuVasive, Inc.
    Inventor: Bret A. Ferree
  • Patent number: 9114250
    Abstract: The invention describes a cuff electrode assembly and method for implanting that includes a resilient cuff body configured to be disposed about a nerve. The cuff body includes a first end portion and a second end portion. The cuff body can be pre-formed to define a closed configuration having a generally annular cross-sectional shape such that, in the closed configuration, the cuff body extends helically with the first and second end portions overlapping on different planes. The cuff electrode assembly includes a first arm member and a second arm member, each projecting radially outward from the cuff body and spaced from one another along the cuff body. The cuff body can be configured such that force applied to urge the first and second arm members toward one another causes relative deflection of the first end portion and the second end portion to define an open configuration of the cuff body.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: August 25, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Kyle True, Brian Soltis