Measuring Fluid Pressure In Body Patents (Class 600/561)
  • Patent number: 11103154
    Abstract: A system and method for collecting operation data associated with a medical apparatus including an internal device implanted in a subject and an external device that is magnetically-coupled to and drives the internal device. The medical apparatus may be monitored to obtain raw data associated with the operation of the medical apparatus and one or more calculations may be performed on the raw data, wherein the raw data and/or calculated values may be associated with voiding frequency and voiding volume of the subject. A report may be generated from the raw data and/or calculated values. In addition, one or more signals may be sent to the external device and/or a docking station, or communicated by other means, to indicate to the subject that the operation of the medical apparatus should be altered.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: August 31, 2021
    Assignee: Vesiflo, Inc.
    Inventors: Kevin M. Connolly, Terence M. Moore, Jean-Marc Gery
  • Patent number: 11103677
    Abstract: A coaxial draining tube, particularly for chest draining systems, includes an inner tube, which has a first opening, and an outer tube, which has a second opening. The inner tube is enclosed within the outer tube and has a smaller diameter than the second opening of the outer tube. The first and second tubes are mutually coupled by way of a supporting component and include one or more holes adapted to allow the passage of air from the chest cavity to the first opening of the inner tube and one or more holes adapted to allow the passage of liquids from the chest cavity to the second opening of the outer tube. The one or more holes are provided in the portion of the coaxial draining tube that is intended to be inserted in the chest cavity of a patient.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: August 31, 2021
    Assignee: REDAX S.P.A.
    Inventors: Andrea Gibertoni, Lucio Gibertoni
  • Patent number: 11090460
    Abstract: A method for delivering an immunotherapy agent to a tumor includes advancing the delivery device into a vessel of a patient, and infusing the agent under pressure into the vessel to penetrate the tumor. The delivery device prevents reflux of the agent toward non-treatment sites.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 17, 2021
    Assignee: Surefire Medical, Inc.
    Inventors: David Benjamin Jaroch, James E. Chomas
  • Patent number: 11083386
    Abstract: Systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position are provided. In some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs. The ports may also be configured such that a barrier is not necessary.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: August 10, 2021
    Assignee: Branchpoint Technologies, Inc.
    Inventors: Nicholas Hu, Kevin Hughes, Hyung Phouasalit
  • Patent number: 11058313
    Abstract: Non-invasive measurement of intracranial pressure (ICP), for example mean ICP. A probe adjacent the head emits energy, such as ultrasound, and receives reflected signals. A processing unit derives ICP waveform from the signals. A pressure mechanism applies external pressure intermittently to outer surface of the head and incrementally increases the external pressure. The processing unit is configured to detect a decrease in amplitude of the ICP waveform (occurring in some embodiments only after an intermediate period of ICRS compensation), the processing unit configured to determine the ICP of the person from a sum of applied external pressures from a time of the initial value A1 until a final value at which the amplitude remains stable with additional increase in applied external pressure. In some cases, the final value is earlier than that but the processing unit extrapolates the sum to when the amplitude remains stable with additional increases in pressure.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: July 13, 2021
    Inventors: David Michaeli, Menashe Michaeli
  • Patent number: 11051978
    Abstract: Ophthalmic surgical devices, systems, and methods for regulating aspiration from a patient's eye are provided. A vacuum pump in fluid communication with an aspiration line provides fluid aspiration from a vitreous chamber of the eye through the aspiration line. A sensor disposed adjacent to or inside the eye determines sensor data relating to an intraocular pressure (IOP). The controller receives the sensor data and regulates the aspiration in response to changes in the IOP, such as by controlling the vacuum pump. The controller may determine whether a fluid infusion to the vitreous chamber through an infusion line is below a maximum infusion level, regulate the infusion in response to the IOP being below a threshold value and the infusion being below the maximum infusion level, and regulate the aspiration in response to the IOP being below the threshold value and the infusion being at or above the maximum infusion level.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: July 6, 2021
    Assignee: Alcon Inc.
    Inventors: Tammo Heeren, Andrew David Johnson
  • Patent number: 11013483
    Abstract: An imaging capsule configured to be swallowed to scan the gastrointestinal tract of a person from the inside, including a radiation source providing X-Ray and gamma radiation for scanning the gastrointestinal tract, a pressure sensor for measuring the internal pressure in the imaging capsule; and wherein the imaging capsule is configured to control the emission of radiation from within the imaging capsule responsive to the measurements of the pressure sensor.
    Type: Grant
    Filed: May 1, 2016
    Date of Patent: May 25, 2021
    Assignee: CHECK-CAP LTD
    Inventors: Dmitry Gubich, Avner Elgali, Yoav Kimchy
  • Patent number: 10912875
    Abstract: A medical system includes a medical fluid pumping machine comprising a pressure sensor, a medical fluid line set comprising a fluid line in fluid communication with a fluid passage formed between a diaphragm and a base, the medical fluid line set being configured to be connected to the medical fluid pumping machine in a manner such that the diaphragm of the medical fluid line set aligns with the pressure sensor of the medical fluid pumping machine, and a member configured to apply a positive force to the pressure sensor when the medical fluid line set is connected to the medical fluid pumping machine and the fluid passage is at atmospheric pressure.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: February 9, 2021
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventor: Michael James Beiriger
  • Patent number: 10881841
    Abstract: A shunt including an implantable housing having a proximal end and a distal end. A pressure sensitive valve is contained within the housing at a position between the proximal end and the distal end, and the pressure sensitive valve is capable of controlling a flow of fluid between the fluid inlet port and the fluid outlet port. The shunt further including a sensor assembly fluidly coupled to the pressure sensitive valve, wherein the sensor assembly is mechanically actuated and capable of detecting the flow of fluid through the pressure sensitive valve. A condition of the shunt can be detected by detecting a flow of fluid through the shunt and generating a signal indicative of a period of fluid flow through the implantable shunt based on the detecting. The signal can be output to an external device capable of determining, from the signal, whether the shunt is malfunctioning.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: January 5, 2021
    Inventor: Siddharth Sadanand
  • Patent number: 10842398
    Abstract: Wireless intracranial monitors are provided. The wireless intracranial monitors comprise a main body, a wireless transceiver, a processing module, and a sensing module, in which the sensing module contains a catheter. On the catheter, a pressure sensor is configured to detect deformation of the catheter or a diaphragm connected to the pressure sensor. The detected deformation is then transmitted to the processing module through an in-catheter wire.
    Type: Grant
    Filed: December 24, 2016
    Date of Patent: November 24, 2020
    Assignee: ORION BIOTECH INC.
    Inventor: Ming-Fu Chiang
  • Patent number: 10791944
    Abstract: A bio-pressure sensor system is disclosed, comprising a first sensor configured to provide a reference pressure measurement and second sensor configured to measure a fluid pressure within a human body. The bio-pressure sensor system also comprises a first reference element and second reference element. The first and second sensors share the first reference element. The second reference element is coupled to the first sensor and configured to provide a reference pressure. The first and second sensors each comprise independent output signals.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: October 6, 2020
    Assignee: ARKIS BIOSCIENCES INC.
    Inventor: Chad Eric Seaver
  • Patent number: 10783993
    Abstract: A system capable of monitoring a replaceable component is provided. The system includes a controller for controlling operation of the system; programming instructions according to which the system is configured to: accept input of a viable life for the component, calculate an accumulated amount of distress experienced by the component based on each set of previously collected use data associated with each previous use of the component, and determine, based in part on the accumulated amount of distress, a used portion of the viable life that the component has experienced as a result of the previous use(s) thereof and an unused portion of the viable life; and a feedback device configured to provide to an operator of the system an indication of at least one of the unused and used portions of the viable life of the component. Methods of monitoring a replaceable component of a system are also provided.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: September 22, 2020
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael Spohn, Michael Swantner, Edward Rhinehart
  • Patent number: 10760006
    Abstract: The present invention provides strategies to integrate adsorption and liquefaction techniques to separate hydrocarbon feed mixtures into purified light and heavy components, respectively. Initially, the hydrocarbon stream is separated into a light and heavy stream. The light stream can be integrated into a natural gas product. The heavy stream is partially liquefied. A first gas liquid separation of the partially liquefied heavy stream at an elevated pressure separates the liquid heavy stream from a methane-containing gas. The rejected methane component, which generally will include some rejected C2 and C3+ material, can be recycled to be combined with the feed mixture for re-processing. A further aspect of the strategy is then to practice at least one additional gas-liquid separation of the separated liquid heavy stream at a lower pressure effective to help further resolve the liquid heavy stream from C2-containing gas.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: September 1, 2020
    Assignee: Dow Global Technologies LLC
    Inventors: Ross E. Dugas, Zubin B. Kuvadia, Preshit Dandekar
  • Patent number: 10751520
    Abstract: Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus includes at least one intracranial catheter and a percutaneous access device. The percutaneous access device includes a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: August 25, 2020
    Assignee: RENISHAW (IRELAND) LIMITED
    Inventors: Steven Streatfield Gill, Paul David Fielder
  • Patent number: 10743815
    Abstract: A device for detecting spatial differences in fluid level changes in a tissue of a patient may include a support structure for securing the device to a body part of the patient, a processing element operably connected to the support structure, a wireless networking interface operably connected to the support structure and in communication with the processing element and an external computing device via a network, a first transmission module operably connected to the support structure and in communication with the processing element, a second transmission module and a third transmission module operably connected to the support structure and in communication with the processing element. When activated, the first transmission module transmits a first time varying magnetic field through the tissue of the patient. The second and third transmission modules, which are spatially separated from one another, receive first and second versions, respectively, of the first time varying magnetic field.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: August 18, 2020
    Assignee: CEREBROTECH MEDICAL SYSTEMS, INC.
    Inventors: Richard Warren Wyeth, Mitchell Elliott Levinson, Bryan Jon Weber
  • Patent number: 10709842
    Abstract: Systems and methods for measuring and damping forces within autoinjectors in accordance with embodiments of the invention are disclosed. In one embodiment of the invention, an injection system comprises a syringe disposed within a housing, the syringe having a first end and a second end; a needle disposed at the second end of the syringe; a plunger disposed at the first end of the syringe and configured to move toward the second end of the syringe; a stopper disposed between the plunger and the second end of the syringe; a first damper disposed between the plunger and the stopper, such that the first damper is capable of damping a first event occurring between the plunger and the stopper; and a second damper disposed at the second end of the syringe, such that the second damper is capable of damping a second event occurring at the second end of the syringe.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: July 14, 2020
    Assignee: California Institute of Technology
    Inventors: Jean-Christophe Veilleux, Joseph Emmett Shepherd
  • Patent number: 10709345
    Abstract: Non-invasive measurement of intracranial pressure (ICP), for example mean ICP. A probe adjacent the head emits energy, such as ultrasound, and receives reflected signals. A processing unit derives ICP waveform from the signals. A pressure mechanism applies external pressure intermittently to outer surface of the head and incrementally increases the external pressure. The processing unit is configured to detect a decrease in amplitude of the ICP waveform (occurring in some embodiments only after an intermediate period of ICRS compensation), the processing unit configured to determine the ICP of the person from a sum of applied external pressures from a time of the initial value A1 until a final value at which the amplitude remains stable with additional increase in applied external pressure. In some cases, the final value is earlier than that but the processing unit extrapolates the sum to when the amplitude remains stable with additional increases in pressure.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: July 14, 2020
    Inventors: David Michaeli, Menashe Michaeli
  • Patent number: 10682100
    Abstract: A measurement system and method for measuring at least one parameter in a body tissue comprise at least one measurement device to be applied to the body, an optical unit for emitting light waves, wherein at least one wavelength of the light waves lies in the region of the absorption of a body parameter, at least one light guide between the optical unit and the measurement device in order to transmit light waves, and an evaluation unit for evaluating measurement waves. Light waves emitted by the optical unit can be beamed into an optical measurement volume in the body tissue by means of the measurement device, and measurement waves received by the measurement device from the measurement volume can be transmitted from the body tissue to the evaluation unit.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: June 16, 2020
    Assignee: Luciole Medical AG
    Inventors: Markus Hugo Muser, Juerg Hans Froehlich, Dirk Baumann
  • Patent number: 10674964
    Abstract: In some examples, a device includes processing circuitry configured to determine a set of correlation coefficient values for first and second physiological parameters. The processing circuitry is further configured to determine a metric of the correlation coefficient values for a first plurality of bins and for a second plurality of bins, wherein each bin of the first plurality has a first bin parameter and each bin of the second plurality of bins has a second bin parameter different than the first bin parameter. The processing circuitry is also configured to determine a composite estimate of a limit of autoregulation of the patient based on the metric for the first plurality of bins and the metric for the second plurality of bins. The processing circuitry is configured to determine an autoregulation status based on the composite estimate and output, for display via the display, an indication of the autoregulation status.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: June 9, 2020
    Assignee: COVIDIEN LP
    Inventors: Paul S. Addison, Dean Montgomery
  • Patent number: 10660530
    Abstract: In some examples, a device includes processing circuitry configured to determine a set of correlation coefficient values for values of first and second physiological parameters. The processing circuitry is further configured to determine that the first physiological parameter changes rapidly in a particular time period. The processing circuitry is configured to select a correlation coefficient value associated with the particular time period and determine an updated value of the selected correlation coefficient value in response to determining that the first physiological parameter changes rapidly in a particular time period. The processing circuitry is further configured to determine an estimate of a limit of autoregulation of the patient based on the set of correlation coefficient values and the updated value. The processing circuitry is configured to determine an autoregulation status based on the estimate of the limit of autoregulation and output, for display, an indication of the autoregulation status.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: May 26, 2020
    Assignee: COVIDIEN LP
    Inventors: Dean Montgomery, Paul S. Addison
  • Patent number: 10617851
    Abstract: In some examples, a catheter may include a catheter body, a first expandable member, and a second expandable member. The catheter body may define a first lumen, a second lumen, a delivery port, and a surface extending from the delivery port into the first lumen. The first lumen may define a first central longitudinal axis. The second lumen may define a second central longitudinal axis spaced from the first central longitudinal axis in a direction orthogonal to the second central longitudinal axis. The delivery port may be in fluid communication with the first lumen. The surface extending from the delivery port into the first surface may be oriented at an obtuse or acute angle relative to the first central longitudinal axis.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: April 14, 2020
    Assignee: Covidien LP
    Inventors: Ujwal Jalgaonkar, Edwin Wang, Edwin Bon
  • Patent number: 10617313
    Abstract: An intrauterine pressure-sensing catheter for detecting pressure changes within the uterus of a patient is disclosed having a tube with a primary lumen extending from a proximal end to a distal end of the elongate tube. A monitor lumen is positioned within the elongate tube between the primary lumen and a wall of the elongate tube and extends from a proximal end of the elongate tube to a distal end of the elongate tube. A pressure-compliant balloon is disposed about an exterior of the elongate tube adjacent a distal end tip. A sleeve is slidably mounted on an exterior of the elongate tube and disposed over the pressure-compliant balloon during insertion of the pressure-sensing catheter within the patient. The distal end tip is configured to prevent movement of the sleeve over the tip and is further configured to provide a zone of protection for the pressure-compliant balloon.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: April 14, 2020
    Assignee: Clinical Innovations, LLC
    Inventor: Steven Smith
  • Patent number: 10598559
    Abstract: A pressure sensor assembly for use in sensing a pressure of a process fluid in a high temperature environment includes an elongate sensor housing configured to be exposed to the process fluid and having a cavity formed therein. A pressure sensor is positioned in the cavity of the elongate sensor housing. The pressure sensor has at least one diaphragm that deflects in response to applied pressure and includes an electrical component having an electrical property which changes as a function of deflection of the at least one diaphragm which is indicative of applied pressure. A flexible membrane in contact with the at least one diaphragm is disposed to seal at least a portion of the cavity of the sensor housing from the process fluid and flexes in response to pressure applied by the process fluid to thereby cause deflection of the at least one diaphragm.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: March 24, 2020
    Assignee: ROSEMOUNT INC.
    Inventors: David Alexander Andrew, David Matthew Strei
  • Patent number: 10542924
    Abstract: A catheter for measuring pressure in the urinary tract of a patient includes a catheter body having a proximal and distal end. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location in the urinary tract to properly position the fluid pressure sensors in the bladder and urethra, respectively.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: January 28, 2020
    Assignee: InCube Labs, LLC
    Inventors: Mir Imran, Ben Tranchina
  • Patent number: 10537274
    Abstract: Systems and methods are provided for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body. An air-charged catheter is configured to record pressure data representing the region of interest. A measurement assembly includes a parameter calculation component configured to calculate at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data. A standardization component is configured to calculate the standardized pressure value as a function of the peak pressure and the time to peak pressure. A user interface is configured to display at least the standardized pressure value at an associated display.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: January 21, 2020
    Assignees: THE U.S. GOVT AS REPRESENTED BY THE DEPT. OF VETERANS AFFAIRS, THE CLEVELAND CLININC FOUNDATION
    Inventors: Margot Damaser, Hassan K. Awada, Paul C. Fletter, Mitchell Cooper, Paul Zaszczurynski
  • Patent number: 10532193
    Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: January 14, 2020
    Assignee: Muffin Incorporated
    Inventors: Frank J. Fischer, Jr., James R. Randolph, Neal E. Fearnot, Jimmy L. Taylor, Jr., Gary B. Shirley
  • Patent number: 10485631
    Abstract: The length of an optical fiber from a portion aligned with the rear end of an insertion needle to a fixing portion is a length obtained by adding a predetermined extra length to a linear distance between the rear end of the insertion needle in a case where the insertion needle is located at a protruding position (insertion position) and an optical fiber fixing position of a grip portion. There is provided a fiber feeding adjustment mechanism that suspends the optical fiber with a first suspension portion and a second suspension portion so as to make a detour in a state in which there is no slack, and changes the detour length continuously according to the movement of the insertion needle in a case where the insertion needle moves between the retracted position and the protruding position, thereby maintaining a state in which the optical fiber is suspended without slack.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: November 26, 2019
    Assignee: FUJIFILM Corporation
    Inventors: Dai Murakoshi, Kaku Irisawa
  • Patent number: 10474307
    Abstract: A material-discerning proximity sensor is arranged to include an antenna that is arranged to radiate a radio-frequency signal. A capacitive sensor is arranged to detect a change in capacitance of the capacitive sensor and to receive the radio-frequency signal. An electrical quantity sensor is arranged to detect a change of the received radio-frequency signal.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: November 12, 2019
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventor: Alan Henry Leek
  • Patent number: 10398494
    Abstract: Methods and surgical tools for treating back pain use a spinal facet debridement tool with cautery and denuding action and minimally invasive protocol that can denude and cauterize soft tissue associated with a synovial capsule of the spinal facet joint.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: September 3, 2019
    Assignee: Medovex Corp.
    Inventors: Robert D. Carter, Adam L. Gullickson, Scott M. W. Haufe, Seth Iverson, Jacob Blank
  • Patent number: 10363049
    Abstract: The invention concerns a cranial drill system comprising one or more surgical drill elements for drilling into the brain. The invention also concerns a cranial drilling system comprising a surgical drill element for drilling into the skull and an element for penetrating the dura. The surgical drill element may comprise a profile that forms an opening in the skull having a narrower diameter portion and a wider diameter portion and the piercing element may be arranged to be a close fit in the narrower diameter portion of the opening. The invention also concerns a cranial drill system comprising a guiding element to be located in a hole formed through the skull and a piercing element for piercing the dura. The guiding element may have a passageway or channel therein for receiving the piercing element such that the piercing element is movable relative to the guide element to pierce the dura.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: July 30, 2019
    Assignee: RENISHAW PLC
    Inventors: Steven Streatfield Gill, Catriona Anita Fennelly
  • Patent number: 10345338
    Abstract: An electronic device includes a housing, which is sized and shaped to fit snugly over a connector containing first electrical contacts at an end of a cable. The electronic device further includes second electrical contacts within the housing and test circuitry. The second electrical contacts are configured and positioned to mate with the first electrical contacts when the housing is fitted over the connector. The test circuitry is contained within the housing and coupled to the second electrical contacts and configured to test a functionality of the cable.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: July 9, 2019
    Assignee: Biosense Webster (Israel ) Ltd.
    Inventor: Avigdor Rosenberg
  • Patent number: 10322224
    Abstract: An apparatus for performing peritoneal dialysis includes a housing; a peritoneal dialysis supply bag supported by and/or located above the housing; a first valve for controlling gravity flow of fresh peritoneal dialysis fluid from the supply bag to a patient; a second valve for controlling gravity flow of used peritoneal dialysis fluid from the patient to a drain; and a pressure sensor positioned and arranged with respect to the gravity flow of fresh peritoneal dialysis fluid or the gravity flow of used peritoneal dialysis fluid to provide a reading used to evaluate a head height pressure.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: June 18, 2019
    Assignee: BAXTER INTERNATIONAL INC.
    Inventors: Robert Warren Childers, Vital Eerlingen, Patrick Balteau, Duane Belongie
  • Patent number: 10307566
    Abstract: A drainage or infusion catheter and methods of use are disclosed. In one embodiment, the catheter includes a tube body having a proximal end and a distal end, and a plurality of ports arranged along the tube body from the distal end to the proximal end. The distal end of the tube body is configured to deform around itself into a substantially spiral shape so as to cover at least one of the plurality of ports located near the proximal end of the tube body. In another embodiment, a flap is configured to erupt from apertures arranged in the tube and extend outwardly around the tube body so as to cover at least one of the plurality of ports located near the proximal end of the tube body.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: June 4, 2019
    Assignee: DUKE UNIVERSITY
    Inventor: Muath Bishawi
  • Patent number: 10307218
    Abstract: One aspect of the present disclosure relates to a stereotactic guide assembly comprising an implantable body and a fastener. The implantable body can have an interior chamber and a first passageway that extends through the implantable body into communication with the interior chamber. At least a portion of the interior chamber can be defined by a first coupling feature. The fastener can be configured to fit in the interior chamber. The fastener can have a second passageway extending therethrough, and a second coupling feature adapted to releasably engage the first coupling feature.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: June 4, 2019
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: John T. Gale, Jorge Gonzalez-Martinez, Shawan J. Anthony
  • Patent number: 10300251
    Abstract: Drug delivery devices and methods are disclosed herein. In some embodiments, a drug can be delivered into a brain ventricle of a subject, where it can diffuse, flow, or otherwise travel across the ependyma and into the hippocampus. The drug can be delivered through a delivery device configured to selectively or transiently obstruct a portion of the ventricle, e.g., the temporal horn or a posterior portion of the temporal horn. The obstruction can define a partitioned volume of the ventricle, limiting or preventing flow of cerebrospinal fluid (CSF) into or out of the partitioned volume. Accordingly, a drug can be delivered into the partitioned volume without being diluted or carried away by CSF, allowing the drug to saturate the ependyma adjacent the hippocampus.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: May 28, 2019
    Assignee: Alcyone Lifesciences, Inc.
    Inventors: Eric Leuthardt, P J Anand
  • Patent number: 10279119
    Abstract: An apparatus includes a syringe body and a plunger. The syringe body defines a volume configured to contain a medicament. A proximal end portion of the syringe body includes an engagement portion, and a distal end portion of the syringe body includes a delivery tip. A side wall of the syringe body includes a transparent window. The plunger has a distal end portion configured to move within the volume of the syringe body to convey the medicament. An engagement portion of the plunger is configured to interface with the engagement portion of the syringe body to limit rotation of the plunger about a longitudinal axis of the plunger. An outer surface of the plunger includes a series of indicia, at least one which is visible through the transparent window.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: May 7, 2019
    Assignee: Brell Medical Innovations, LLC
    Inventor: Jeffrey M. Leary
  • Patent number: 10265509
    Abstract: Devices and methods useful for storing and retrieving information related to a medical device such as an implantable valve or an implantable sensor are disclosed. An implantable valve can include a valve housing adapted to receive fluid flow therethrough between a valve inlet and a valve outlet. A valve assembly can be disposed within the valve housing and adapted to control a rate of fluid flowing through the valve housing. The implantable valve can also include a radio frequency identification (RFID) tag associated with the valve housing, adapted to store data, and including an antenna for communicating stored data to an external reading device. The RFID tag can store data related to, for example, a patient, a pressure setting of the valve assembly, and/or pressure sensor disposed within the valve. The RFID tag can also store an identifier that identifies the implantable valve, a pressure sensor disposed in the valve housing, a patient associated with the implantable valve, and/or patient clinical history.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: April 23, 2019
    Assignee: INTEGRA LIFESCIENCES SWITZERLAND SARL
    Inventor: Salim Kassem
  • Patent number: 10219725
    Abstract: A patient support apparatus includes a control system that measures changes in the pressure of one or more zones of a patient supporting surface and utilizes the changes in pressure to determine the mobility of a person supported on the patient supporting surface. The mobility of the person may be measured using one of several methods. The mobility measurement results in the determination of a mobility score. The mobility score is graphically displayed on a user interface that is interactive and allows a user to view additional information besides the mobility score.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: March 5, 2019
    Assignee: Hill-Rom Services, Inc.
    Inventors: Rachel L. Williamson, Robert M. Zerhusen, Charles A. Lachenbruch, Timothy J. Receveur, Nicholas C. Batta, Yaoning Wu
  • Patent number: 10166375
    Abstract: Drainage systems for excess body fluids and associated methods are disclosed herein. A body fluid drainage system in accordance with an embodiment of the present technology, for example, can include a catheter that has an exterior surface, a proximal portion, and a distal portion opposite the proximal portion. The body fluid drainage system can further include a valve device, a pressure sensor, and a controller operatively coupled to the valve device and the pressure sensor. The valve device can include an actuator positioned over the exterior surface of the catheter. The actuator is movable between an open position that allows body fluid flow through the catheter, a closed position that at least substantially obstructs the body fluid flow through the catheter, and intermediate positions that partially obstruct the body fluid flow through the catheter. The controller can change the position of the actuator in response to a predetermined condition of the pressure sensor.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: January 1, 2019
    Assignee: University of Washington
    Inventors: Samuel R. Browd, Barry R. Lutz
  • Patent number: 10092195
    Abstract: Vascular conditions are detected non-invasively in the human body using a collection of information from small local regions of the vasculature, or from a specific signature or “BrainPulse” that can be derived from a patient's heartbeat-induced cranium movements. An array of accelerometers or other sensors are engaged against the head of a patient and skull movements, preferably under 100 Hz, are recorded. Vibration signatures of vessel structures such as branches, aneurysms, stenosis, etc. using random, periodic, band limited or transient analysis provides a library for further processing. The signature library is used to localize the origin of the recognized vascular feature, and the localized feature is presented to the physician in a clinically relevant manner.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: October 9, 2018
    Assignee: JAN MEDICAL, INC.
    Inventors: Paul A. Lovoi, Ray Schumacher, Charlie MacVean
  • Patent number: 10090655
    Abstract: A conduit box assembly including: a housing defining an interior chamber; arms extending outward from the housing, wherein the arms each have a wall defining a passage into the chamber; a compressible seal for each of the arms, wherein each seal has an outer surface configured to seat in and abut the wall of the arm receiving the seal, and a cover configured to attached to the housing and cover an open side of the housing, wherein the cover includes arms extending outward from a center portion the cover and the arms are each configured to cover an open side of a respective one of the arms of the housing and compress the seal in the respective arm.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: October 2, 2018
    Assignee: General Electric Company
    Inventors: Edgar Eduardo Luna, Luis Martinez
  • Patent number: 10076274
    Abstract: Vascular conditions are detected non-invasively in the human body using a collection of information from small local regions of the vasculature. An array of accelerometers are attached to the head and blood flow sounds are recorded. Vibration signatures of vessel structures such as branches, aneurysms, stenosis, etc. using random, periodic, band limited or transient analysis provides a signature library for further processing. The signature library is used to localize the origin of recognized vascular features and the localized feature is presented to the physician in a clinically relevant manner.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: September 18, 2018
    Assignee: JAN MEDICAL, INC.
    Inventors: Paul A Lovoi, Kieran Murphy, Jeff Jarvela, Pete Neild, John Thomas, Ray Schumacher, Charlie Macvean
  • Patent number: 10004450
    Abstract: Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: June 26, 2018
    Assignee: TEXAS MEDICAL CENTER
    Inventors: Nicole C. Moskowitz, Jessica Traver, Xavier Garcia-Rojas, Yashar Ganjeh
  • Patent number: 9980745
    Abstract: A guide tube is used for guiding an instrument through a hole within tissue of a patient. The guide tube includes a cannula member defining a passage extending therethrough along an axis. The passage is operable to receive the instrument and guide the instrument through the hole within the tissue of the patient. The guide tube also includes an expansion member that is moveably coupled to the cannula member to selectively move radially between a retracted position and an expanded position relative to the axis of the cannula member. The expansion member is at least partially insertable into the hole when the expansion member is in the retracted position. The expansion member is operable to engage with a surface of the hole when the expansion member is in the expanded position.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: May 29, 2018
    Assignee: Medtronic Navigation, Inc.
    Inventors: Bruce M. Burg, Brad Jacobsen
  • Patent number: 9949647
    Abstract: The invention relates to a sensor and guide wire assembly (21) for intravascular measurements of physiological variables in a living body, comprising a core wire (22), a first coil (23), a jacket (24), and a second coil (25). The jacket (24) comprises a first end portion (24a), which is crimped onto the core wire (22) and over which a portion of the first coil (23) is threaded, and a second end portion (24b), which is crimped onto the core wire (22) and over which a portion of the second coil (25) is threaded.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: April 24, 2018
    Assignee: ST. JUDE MEDICAL COORDINATION CENTER BVBA
    Inventors: Leif Smith, Ola Hammarström, Per Egnelöv, Dan Åkerfeldt
  • Patent number: 9949646
    Abstract: The present document describes a pressure guidewire comprising a shaft tube, a tip portion and a fiber optic pressure sensor. The shaft tube comprises a middle section and a sensor housing extending distally relative to the middle section, the sensor housing having a distal end. The tip portion extends distally relative to the shaft tube. The pressure sensor is embedded in the sensor housing. The sensor housing defines a cavity, inside the sensor housing, which is distal relative to the pressure sensor and delimited at a proximal end thereof by the pressure sensor.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: April 24, 2018
    Inventor: Claude Belleville
  • Patent number: 9931043
    Abstract: A pressure sensing apparatus has a pressure sensor component that includes a pressure sensing port, a pressure sensor for sensing a pressure of a fluid in the pressure sensing port, and a digital processor communicating with the pressure sensor for performing calculations involving fluid pressures sensed. The pressure sensing apparatus further includes a first chamber in fluid contact with the pressure sensing port, a second chamber fluidically connectable with a patient's cerebrospinal fluid system, and a membrane located between the first and second chambers so as to transmit fluid pressure from the second chamber to the first chamber.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: April 3, 2018
    Assignee: INTEGRA LIFESCIENCES SWITZERLAND SÀRL
    Inventors: Stephen F. Wilson, Alan J. Dextradeur
  • Patent number: 9931477
    Abstract: An apparatus provides feedback regarding the material in which tip of the apparatus is located as the tip is advanced into matter of varying resistances. The apparatus responds to a change in pressure, force, or other parameter such that when the tip reaches matter of a certain resistance, a change in the parameter is sensed. The apparatus provides a driving force to a penetrating medical device, such as a needle, when the apparatus tip encounters material of high resistance. When the apparatus tip encounters a low resistance material, no further driving force is applied to the apparatus. An inner core may be advanced into the low resistance material for deployment of a gas or a liquid as desired.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: April 3, 2018
    Assignees: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Erik Bassett, Jeffrey M. Karp, Robert S. Langer, Omid C. Farokhzad, Alexander H. Slocum
  • Patent number: 9901269
    Abstract: Systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position are provided. In some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs. The ports may also be configured such that a barrier is not necessary.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: February 27, 2018
    Assignee: Branchpoint Technologies, Inc.
    Inventors: Nicholas Hu, Kevin Hughes, Hyung Phouasalit
  • Patent number: 9848789
    Abstract: Some embodiments of the present disclosure comprise improved systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position. For example, in some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: December 26, 2017
    Assignee: Branchpoint Technologies, Inc.
    Inventors: Nicholas Hu, Kevin Hughes, Hyung Phouasalit