Abstract: There is shown and described embodiments of a biopsy needle that is simpler to make and use than existing devices. An inner and outer cannula are provided, with the outer cannula having a superelastic finger that lies along the length of the inner cannula in a retracted position and partially covers the lumen of the inner cannula in an extended position. The finger is pointed and in the form of a triangle in a particular embodiment, and does not extend beyond the outer extent of the inner cannula in the extended position.

Abstract: The present invention provides for exemplary embodiments of a single-insertion, multiple sampling biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release.

Abstract: Medical procedure trays and related methods are provided to accommodate joining a first non-sterile medical device with a second sterile medical device and maintaining required sterilization of the second sterile medical device to perform an associated medical procedure. One example of such medical procedures includes biopsy of a bone and/or associated bone marrow using a non-sterile powered drive and a sterile biopsy needle or biopsy needle set. Medical procedure trays and related methods may also be provided for use during aspiration of bone marrow and/or stem cell transplant procedures. Each medical procedure tray may include a containment bag or sterile sleeve. A coupler assembly, one or more sharps protectors, a biopsy sample ejector and/or associated ejector funnel may also be included.

Abstract: A method for obtaining a full thickness biopsy of the wall of a hollow organ, comprising obtaining an apparatus comprising a cannula comprising a proximal cannula end comprising a cutting edge; and a distal cannula end comprising a biased spring, the biased spring being coupled to a needle carrier and a releasable lock; and a needle disposed within the cannula and carried on the needle carrier, the needle comprising: a tip; a flange; a notch portion comprising a notch thickness; and a shaft comprising a shaft thickness; where the shaft thickness is greater than the notch thickness and the releasable lock is configured to hold the cannula in a withdrawn position relative to the needle; obtaining a patient having skin, a first wall, and a second wall; creating an incision through the skin of the patient; inserting the apparatus into the incision; advancing the apparatus through the first wall and the second wall; withdrawing the cannula relative to the needle; locking the cannula with the releasable lock; align

Abstract: A device for sampling biological tissue (1) to be used in a label for marking animals includes: a hollow needle (3) having a cutting edge (36) at one end, capable of sampling a biological tissue sample when the sampling device is inserted into the biological tissue; a fixation part (22) of the hollow needle, made as a single piece and including a tank (2) containing a chemical for processing a biological tissue sample, the base of the tank including a partition (211) that is punctured by the needle when a pressure is applied upon the insertion of the sampling device into the biological tissue. After puncturing the partition, the content of the tank flow into the hollow needle and contacts the recovered sample. The end of the hollow needle containing the sample can further be protected by a cap, and the sample remains easily accessible for further analysis.

Abstract: A biopsy device includes a body, a needle, and a cutter. A motor is operable to both move the cutter relative to the needle and actuate a needle firing assembly to retract and fire the needle relative to the body. The biopsy device also includes a needle rotation assembly that is configured to substantially prevent rotation of the needle about the longitudinal axis when the needle is in a proximal position yet permit rotation of the needle about the longitudinal axis when the needle is in a distal position. A valve assembly of the biopsy device includes a slider that selectively couples a secondary lumen in the needle with either atmospheric air or saline based on the longitudinal position of the slider. The cutter passes through the slider.

Abstract: A biopsy needle set includes an introducer cannula having an elongate tubular body defining a lumen extending from an open proximal end to an open distal end. The introducer cannula also includes a lateral opening through a distal segment of the elongate tubular body that is in fluid communication with the lumen. The biopsy needle set also includes a biopsy needle configured to be telescopically received within the lumen of the introducer cannula. The biopsy needle includes a preformed curve causing a distal tip of the biopsy needle to point in a direction that is offset from a longitudinal direction of the introducer cannula. The biopsy needle set includes a first extended configuration in which the distal tip is advanced through the lateral opening and a second extended configuration in which the distal tip is advanced through the open distal end.

Abstract: The invention provides a device 10 for analysis of tissue cells 12 in a living body, the device comprising a stylet 14, the stylet comprising a clad optical fiber senior 18 enveloped in a tubular jacket 20, wherein an unclad area 24 of the fiber and a jacket window 26 corresponding to the unclad area are proximate to the distal end 28 thereof, the optical fiber 18 being linked at a proximate end 30 to receive light from a light source 32, the device further including a light analyzer 34 for measuring qualities of output light at the depth at which the unclad area 24 is positioned in the body during use, an electronic data processor 36 being linked between the light analyzer 34 and a display 38 provided to show real-time data regarding any area 40 evidencing a change in optical properties of body tissues being successively examined.

Abstract: An expandable biopsy device and a method of obtaining a biopsy sample are provided. The expandable biopsy device includes an expandable portion including an expandable plate member and a cable operably connected to the expandable plate member. The expandable plate member has a substantially flattened configuration and an expanded configuration where the expanded configuration is longitudinally elongated relative to the flattened configuration. The flattened configuration has a first diameter. The expandable biopsy device also includes a cutting portion including a blade and a housing. The blade is positionable at least partially within the housing and the blade has a second diameter. The housing includes an opening and a cavity formed within housing. The second diameter of the blade is greater than the first diameter of the expandable plate member in the substantially flattened configuration.

Abstract: Tools and methods of use for removing biological units from a body surface utilizing a removal tool are disclosed. The tool incorporates a retention member configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. The retention member is radially movable within the lumen of the biological unit removal tool. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit.

Abstract: The present invention relates to an endoscopic instrument for retrograde biopsy, in particular synovial biopsy, comprising a head unit (12) having a distal tip portion (36) for penetrating tissue, a jaw part (24) with a tissue engaging formation (38) for removing the biopsy specimen, the jaw part (24) being pivotable from an idle position to an operating position in the direction of the distal tip portion (36) and back, wherein the tissue engaging formation (38) is essentially oriented away from the distal tip portion (36) in the operating position, as well as a first fluid channel area (76) open to the surrounding area in the region of the head unit (12), wherein the first fluid channel area (76) is at least open to the surrounding area via at least one channel opening (78) provided in the jaw part (24), when the jaw part (24) is in idle position.

Abstract: Various components of an interventional therapy assembly are disclosed. One such component is a pointer which may be configured to indicate the disposition of another portion or component of the assembly. A rotary indexing device which may be configured to control or facilitate rotation of other components is also disclosed. Further, various components of an elongate instrument having flexible segments and operative segments are also disclosed. In some embodiments, the elongate instrument may comprise a biopsy assembly and may be used in connection with other components of the disclosed assembly.

Abstract: A drive system is provided for rotating and translating a biopsy member. The drive system includes housing having an opening having housing threads. A device gear within the opening has device gear threads that mate with the housing threads. A biopsy member is fixed to the device gear. The device gear threads have gear teeth that mate with pinion teeth that are disposed circumferentially on a pinion. A drive is configured to rotate the pinion thereby rotating and translating the biopsy member relative to the housing.

Abstract: Disclosed herein is an insertable probe for diagnosis of lesional tissue in real time. The insertable probe includes a guide needle inserted into the human body and having a hollow shape of a predetermined length, a storage connected to the guide needle, a tissue collection portion collecting a predetermined amount of tissue in the human body and moving the collected tissue to the storage through the guide needle, and an inspection unit inspecting the tissue stored in the storage. A method of manufacturing an electrode using the same is also disclosed.

Abstract: A tissue sampling apparatus and method are disclosed. Some embodiments comprise a biopsy needle having a laterally expandable distal portion comprising spines which move away from each other when unconstrained and which move towards each other when constrained to do so a sheath. In some embodiments said spines comprise inward-pointing teeth designed to catch tissue samples when said needle retracted from tissue. A method of use comprises providing such a needle within a sheath, advancing the sheath to near a sampling site, advancing needle beyond sheath to expand the expandable portion, retracting needle into sheath so that the expandable portion collapses and tissue samples are trapped between the teeth and spines, and removing the needle and the samples it contains from the body.

Abstract: The present invention is directed to tissue removal devices and methods. A tubular element having an open distal end is advanced into tissue so that tissue enters the tubular element. The tissue, which entered the tubular element is cut to separate the tissue from the surrounding tissue. The tissue is then transported proximally by the cutting element or a separate transport element.

Abstract: This invention relates to a biopsy device consisting of an inner cannula (4) and an outer hollow tube (1), a handle (7) which may be removably attached to the outer hollow tube, a locking system to secure the inner cannula and/or the attenuator in the outer hollow tube, and characterized in that the tip of the outer hollow tube is ellipse shaped and extends beyond the inner cannula, the latter ending in a blunt edge. The blunted tip of the outer hollow tube together with the sharpened ending of the inner cannula determines the cutting edge of the device. In combination the distal ends of inner cannula and outer hollow tube determine the biopsy depth size and shape of the biopsy sample in a reproducible way. In one embodiment of the present invention, the length of the inner cannula can be controlled, allowing varying the aforementioned sample parameters as desired.

Abstract: An adjustable coaxial needle assembly for placement into a tissue mass prior to a biopsy procedure comprises a guide cannula assembly, a stylet, and a throw calibrator. The stylet is selectively coaxially received by the guide cannula, which is in turn coaxially received by the throw calibrator. The effective length of the guide cannula can be selectively adjusted by moving the throw calibrator relative to the guide cannula to adjust the distance between an open distal end of the guide cannula and a the throw calibrator.

Abstract: A lung biopsy tool having a deployable snare and an inflatable pull type cutter for removing small samples of tissue.

Abstract: A biopsy needle system includes a carrier. A trocar is inserted into the carrier for percutaneous insertion to a biopsy site. A biopsy needle is inserted into the carrier, replacing the trocar, for removal of a tissue biopsy specimen. A biopsy needle and a method for obtaining a tissue biopsy specimen with the system, are also provided.

Abstract: A biopsy needle system includes a carrier. A trocar is inserted into the carrier for percutaneous insertion to a biopsy site. A biopsy needle is inserted into the carrier, replacing the trocar, for removal of a tissue biopsy specimen. A biopsy needle and a method for obtaining a tissue biopsy specimen with the system, are also provided.

Abstract: A bone marrow aspiration assembly including an outer cannula and an inner cannula. The inner cannula is moved only radially about a longitudinal axis thereof with respect to the outer cannula to selectively align inner openings of only one of distal, intermediate, and proximal opening groups of the inner cannula with outer openings of only one of distal, intermediate, and proximal opening groups of the outer cannula to permit aspiration therethrough.

Abstract: The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release.

Abstract: A biopsy device includes a body, a needle, a cutter, a motor, a power source, a vacuum source, and a cutter translation assembly. The needle extends distally from the body and receives tissue. The cutter translates with respect to the needle to sever tissue received by the needle. The motor is disposed within the body and rotates a drive shaft in a first direction. The power source is disposed within the body and powers the motor. The vacuum source is disposed within the body and provides vacuum in at least one of the needle and the cutter. The cutter translation assembly is disposed within the body and translates the cutter proximally and distally with respect to the needle in response to rotation of the drive shaft in the first direction.

Abstract: The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release.

Abstract: A biopsy device comprises a coring and transport assembly and a distal beak assembly. The distal beak assembly may be coupled to or near a distal end of the coring and transport assembly and may comprise at least one movable cutting element. The distal beak assembly may be configured to rotate about an axis, and assume at least a first open configuration operative to enable the at least one cutting element to core through tissue and a second closed configuration operative to enable the at least one cutting element to move through the tissue and to sever a cored specimen from the tissue.

Abstract: A biopsy device comprises a coring and transport assembly and a distal beak assembly. The distal beak assembly may be coupled to or near a distal end of the coring and transport assembly and may comprise at least one movable cutting element. The distal beak assembly may be configured to rotate about an axis, and assume at least a first open configuration operative to enable the at least one cutting element to core through tissue and a second closed configuration operative to enable the at least one cutting element to move through the tissue and to sever a cored specimen from the tissue.

Abstract: A biopsy device comprises a coring and transport assembly and a distal beak assembly. The distal beak assembly may be coupled to or near a distal end of the coring and transport assembly and may comprise at least one movable cutting element. The distal beak assembly may be configured to rotate about an axis, and assume at least a first open configuration operative to enable the at least one cutting element to core through tissue and a second closed configuration operative to enable the at least one cutting element to move through the tissue and to sever a cored specimen from the tissue.

Abstract: A biopsy device includes a coring cannula, a retract stylet, and a localization needle. The coring cannula has a longitudinal axis and a shaft centered on the axis. The stylet has a tip containing at least one blade and a central passage. The localization needle has a channel and is slidably disposed within the central passage. A drive mechanism rotates the cannula and moves the cannula in a direction parallel to the longitudinal axis of the cannula. A guide element has a first end and a second end and is slidably disposed within the channel of the localization needle. The guide element is movable from a first position to a second position within the localization needle.

Abstract: This treatment tool for biopsy includes a needle tube, which having a first aperture and a second aperture. The first aperture and the second aperture communicate with the tubular space. The second aperture is provided in a side surface of the needle tube at more proximal end side than the first aperture. In a cross-section of the second aperture, a distal end circular arc portion of an end surface of the second aperture has a distal end side inclined surface that is inclined so as to be positioned gradually outwards of a radial direction of the needle tube towards the distal end side, and a proximal end circular arc portion of the end surface of the second aperture has a proximal end inclined surface that is inclined so as to be positioned gradually outwards of the radial direction of the needle tube towards the proximal end side.

Abstract: A biopsy apparatus includes a driver assembly to be grasped by a user and a disposable biopsy probe assembly for releasable attachment to the driver assembly. The driver assembly includes a first vacuum path having a first one-way valve configured and arranged to permit a negative pressure fluid flow toward a vacuum source and to prevent a positive pressure fluid flow away from the vacuum source. The disposable biopsy probe assembly includes a second vacuum path having a second one-way valve configured and arranged to permit the negative pressure fluid flow from a sample basket and to redundantly prevent the positive pressure fluid flow toward the sample basket. In some embodiments, a fluid management tank may be fluidically interposed in the second vacuum path to prevent a flow of residual biopsy biological material from the sample basket to the vacuum source.

Abstract: A biopsy apparatus includes a driver assembly to be grasped by a user and a disposable biopsy probe assembly for releasable attachment to the driver assembly. The driver assembly includes a first vacuum path having a first one-way valve configured and arranged to permit a negative pressure fluid flow toward a vacuum source and to prevent a positive pressure fluid flow away from the vacuum source. The disposable biopsy probe assembly includes a second vacuum path having a second one-way valve configured and arranged to permit the negative pressure fluid flow from a sample basket and to redundantly prevent the positive pressure fluid flow toward the sample basket. A vacuum monitoring mechanism is coupled to the vacuum source and configured to shut off the vacuum source when a vacuum level in at least one of the first vacuum path and the second vacuum path reaches a predetermined level.

Abstract: A biopsy apparatus includes a driver assembly and a disposable biopsy probe assembly for releasable attachment to the driver assembly. The driver assembly includes a first vacuum path having a first one-way valve configured and arranged to permit a negative pressure fluid flow toward a vacuum source and to prevent a positive pressure fluid flow away from the vacuum source. The disposable biopsy probe assembly includes a second vacuum path having a second one-way valve configured and arranged to permit the negative pressure fluid flow from a sample basket and to redundantly prevent the positive pressure fluid flow toward the sample basket. A fluid management tank is fluidically interposed in the second vacuum path between the first end and the second end. The fluid management tank includes a filter arrangement to prevent a flow of residual biopsy biological material from the sample basket to the vacuum source.

Abstract: A biopsy device includes a probe, a holster, and a tissue sample holder for collecting tissue samples. The probe includes a needle and a hollow cutter. The tissue sample holder includes a housing having a plurality of chambers that are respectively configured to receive a tray. The housing is releasably engageable with the probe. Each tray is configured to receive a tissue sample communicated through the cutter lumen. Each tray is removable from the housing, such as along an axial direction. The tissue sample holder is rotatable to successively index each chamber to the cutter lumen. A tray retainer is operable to selectively secure the trays relative to the housing. The trays may be flexible, resilient, or rigid.

Abstract: A method for extracting a tissue sample includes altering the pressure inside the lumen of a cannula to facilitate extraction of a tissue sample from the cannula. One aspect of the invention includes a biopsy apparatus comprising a valve for controlling the pressure inside the lumen of the cannula. In one variation, the pressure/vacuum generating device is connected to a cannula with a closed distal end and an orifice located on a circumferential surface of said cannula. A cutting sheath is slidably disposed over said cannula. The valve may be provided between the pressure/vacuum generating device and the cannula to control the pressure within the lumen of the cannula.

Abstract: A biopsy apparatus includes a cannula, a cutting sheath, a pressure generating device and a valve. The cannula has a lumen, a proximal portion, a closed distal end, and an orifice located on a circumferential surface of the cannula. The orifice is configured to receive a tissue sample into the lumen of the cannula. The cutting sheath is coaxially disposed with the cannula. The cutting sheath is configured to be movable relative to the cannula to selectively cover the orifice. The pressure generating device is coupled to the proximal portion of the cannula. A valve is interposed between the cannula and the pressure generating device. The valve is configured to control a flow of a fluid between the lumen of the cannula and the pressure generating device.

Abstract: A needle assembly comprises an outer cannula and an inner cannula. The outer cannula and the inner cannula have complementary tissue receiving apertures. A tissue piercing tip is secured relative to one or both of the inner cannula or the outer cannula. A cutter is slidably disposed in the inner cannula. The cutter is configured to sever tissue protruding through the transverse apertures. A hub releasably secures at least part of the needle assembly relative to the body of a biopsy device.

Abstract: A biopsy needle comprises a first lumen open to a tissue penetrating distal tip of the needle for receiving a tissue sample therein and a second lumen in combination with a filter separating the first and second lumens from one another, the filter being configured to permit fluids to pass therethrough while preventing the sampled tissue from passing therethrough.

Abstract: A tissue and/or cell sampling device for biopsies having a catheter sized for translation through a lumen on an instrument such as a bronchoscope. An aspiration needle engaged to a control member is employable by translation to remove a core of tissue from a sampling location. The translation can be limited to maintain the needle retracted into an axial passage. Forceps or a brush are translatably engaged within the axial core of the needle and are translatable from the tip of the needle to take tissue and/or cell samples. The device is employable to allow for use of either sampling device independently, or sequently, to allow deep tissue and/or cell samples to be retrieved from the distal end of the core tissue sample retrieved by the needle.

Abstract: A biopsy system comprising a probe and a holster. The probe comprises a rotatable needle portion a rotatable thumbwheel coupled with the needle portion and a rotatable tissue sample manifold. The holster is removably coupled to the probe. The holster comprises a selective engagement mechanism configured to selectively link rotation of the thumbwheel with rotation of the tissue sample manifold. A method of collecting tissue samples using a biopsy system unlinking rotation of the thumbwheel with rotation of the tissue sample manifold by actuating the selective engagement mechanism; and obtaining a tissue sample after the unlinking.

Abstract: A rotary tissue-collection needle configured is provided with a closed distal tip and a distal aperture including a generally longitudinal cutting edge configured to excise tissue into the aperture for collection by rotation of the needle. The needle may be provided as part of a system including an outer sheath within which the needle may be rotated. The needle may be provided with echogenicity-enhancing features.

Abstract: A tissue removal apparatus and needle assembly for extracting a tissue portion from tissue or the like, the needle assembly comprising an inner tube having an interior cavity, an outer cannula having a proximal end, a distal end and an interior cavity, the interior cavity of the outer cannula having an interior diameter to slidably receive the inner tube and a collapsible section operably engaged with the inner tube and the outer cannula whereby a forward movement of a portion of the inner tube within the interior cavity of the outer cannula changes the collapsible section from a neutral position to a collapsed position to engage the tissue portion. A method of tissue removal comprising the steps of positioning a needle assembly in a tissue, engaging a tissue portion and withdrawing the needle assembly to remove the tissue portion from the tissue.

Abstract: A biopsy device includes a body portion, a tip, at least one blade, and a cutter. The cannula defines at least one lumen. The cannula has a transverse aperture configured to receive tissue. The tip is located at the distal end of the cannula, and may include at least two concave surfaces. The blade extends longitudinally from the tip. A second blade may also extend longitudinally from the tip. Blades may be axially staggered relative to the cannula. Blades may also have lengths that differ from one another. In addition, a blade may have a pointed distal end, or may have a curved distal edge. The configuration of the blade and tip may provide reduced force to penetrate tissue. The blade and tip may produce a cut length that is greater than or equal to the length of the outer perimeter of the cannula.

Abstract: The present invention relates to a device (1) to allow providing testing of tissue of prostate gland (3) using two or more biopsy needles (4, 5, 6, etc.) essentially simultaneously. According to the invention a guiding (7) for said needles (4-6) is arranged to act on said needles, which preferably have a built-in curvature,-.so that the needles (4-6) are curved by said guiding to get the needles, when using the device, to extend along a peripheral part of the prostate gland (3) in question to allow testing in said peripheral part (2) of the same.

Abstract: A biopsy device includes a probe assembly and a driver unit. The probe assembly includes a first cannula having a first aperture extending to a lumen proximal to a first distal end of the first cannula. A second cannula has a second aperture extending to a lumen proximal to the second distal end of the second cannula. The second cannula is disposed co-axially with the first cannula. A least one of the first aperture and the second aperture has a cutting edge. The driver unit is configured for releasably mounting the probe assembly. The driver unit is operatively configured to simultaneously rotate the first cannula and the second cannula at different rotational velocities so that the first aperture and the second aperture periodically come into alignment to form a virtual tissue sample aperture.

Abstract: A biopsy device comprises a body, a needle, and a cutter operable to sever tissue protruding through a lateral aperture of the needle. A vacuum pump is in fluid communication with the cutter. A fluid pump is in fluid communication with the needle. A fluid pump actuation assembly is operable to actuate the fluid pump to deliver a bolus of fluid to the needle based on movement of the cutter. A valve assembly responsive to cutter movement is operable to selectively couple the needle with the fluid pump, couple the needle with atmospheric air, or seal the needle relative to the fluid pump and atmospheric air. The fluid from the fluid pump and atmospheric air cooperate with the vacuum to urge severed tissue samples proximally through the cutter. Components operable to actuate the cutter and the fluid pump include coaxial lead screws having different pitch diameters.

Abstract: An image guided biopsy grid markable with marking medium for marking a subject's skin underlying the grid with a marking to identify a needle entry target. The grid includes a flexible substrate and a plurality of substrate pores extending therethrough. An adhesive layer on the underside of the substrate conformingly and removably attaches the substrate to the skin substantially without gapping therebetween. The adhesive layer defines a plurality of adhesive pores and/or adhesive free spaces that allow marking medium to flow through the adhesive layer and onto the skin to mark the skin and identify the needle entry target. The biopsy grid may be marked substantially anywhere along its upper surface and marking medium will pass therethrough and mark the skin.

Abstract: A biopsy device includes a body portion, a cannula, a cutter, and a tissue stop having a proximal face. The cannula has a transverse aperture that is defined in part by a proximal edge and a distal edge. The cutter is movable to a distal position to sever tissue protruding through the transverse aperture. A tip at the distal end of the cannula has a sharp edge that extends proximally to a longitudinal position that is proximal to the longitudinal position of the distal edge of the transverse aperture. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the distal cutting edge of the cutter when the cutter is at the distal position. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the proximal face of the tissue stop.

Abstract: A system configured for use in an anatomical luminal network of a patient includes an extended working channel and a navigation system for guiding one or more tools, the extended working channel, or a locatable guide through a luminal network following a predetermined pathway to target tissue. The extended working channel is configured to provide passage for a tool. The extended working channel includes a bleeding containment device including a balloon portion and an inflation duct.

Abstract: A holding structure holds a biopsy needle and a HIFU transducer to allow smooth and accurate delivery of the HIFU beam at the interface of the liver, where bleeding will occur. This manipulator structure performs the biopsy and HIFU through the percutaneous approach. In addition, the procedure is imaged by an imaging ultrasound probe. This imaging ultrasound probe can track the needle entry site even when needle has been removed. The HIFU transducer fires a short pulse of HIFU in the needle tract to cause coagulation and stop bleeding.