Brushing Patents (Class 600/569)
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Publication number: 20110021950Abstract: A medical device includes a sheath defining at least one lumen and a probe movably disposed within the lumen. The probe includes a removable handle at a proximal end thereof, a collector at a distal end thereof, and a stop disposed between the proximal end and the distal end. The medical device also includes a preservative disposed within the lumen.Type: ApplicationFiled: July 22, 2009Publication date: January 27, 2011Applicant: Father Judge Apostolic Land Company, LLCInventor: Robert L. Daniels
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Patent number: 7871574Abstract: A flask for preparing a fixer-based cytological suspension is equipped with a filtering element (4) at least partly immersed in the suspension. The filtering element is in the form of a basket-forming filtering material web, whereof the periphery (5) is fixed on the flask and whereof the center (6) is connected to a tube (7), extending towards the opening (2) of the flask, associated with a position-maintaining element (8) in the flask and adapted to allow through a pipette for drawing the suspension.Type: GrantFiled: November 28, 2005Date of Patent: January 18, 2011Assignee: MaclipInventor: Eric Peltier
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Patent number: 7857813Abstract: A method and system for guiding at least a portion of a surgical device to a desired position between two tissues in a patient's body involves coupling a guidewire to the device and pulling the distal end of the guidewire to guide at least a portion of the surgical device to a desired position between the two tissues. The surgical device generally includes one or more guidewire coupling members and may comprise a tissue access device. A system may include a guidewire and a surgical device. In some embodiments, a guidewire, a tissue access device, and one or more additional devices to use with the access device may be provided. Methods, devices and systems may be used in open, less-invasive or percutaneous surgical procedures, in various embodiments.Type: GrantFiled: August 29, 2006Date of Patent: December 28, 2010Assignee: Baxano, Inc.Inventors: Gregory Schmitz, Jefferey Bleam, Roy Leguidleguid, Jeffery L. Bleich
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Publication number: 20100305471Abstract: The present invention relates generally to devices and systems for detecting infection within catheters. In particular, the present invention provides catheter testing systems configured to sterilely collect a biological sample from the interior of a catheter for purposes of testing the biological sample (e.g., for the presence of fibrin, sepsis, etc.).Type: ApplicationFiled: August 4, 2010Publication date: December 2, 2010Inventors: Robert Brewer, Richard Julius, Michael Julius, Joseph Mattano, Kevin Davidson
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Patent number: 7824342Abstract: A tissue cutting device includes an insertion section which is inserted inside a specimen and extends from a distal end to a proximal end, openings which are formed in a distal end side of the insertion section inserted into the specimen, tissue cutting members which pass through the openings, extend such as to protrude in a direction intersecting the axial line of the length direction from the distal end of the insertion section to the proximal end, and are drawn into the insertion section from the same openings after forming a loop which tissue can be inserted into, a control member which is connected to the tissue cutting members, and a controller for controlling the control member; tissue passed through the loops being cut by controlling the control member and drawing the tissue cutting members from the openings into the insertion section.Type: GrantFiled: February 3, 2006Date of Patent: November 2, 2010Assignee: Olympus Medical Systems Corp.Inventors: Ryo Minosawa, Koji Shimomura
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Publication number: 20100249649Abstract: A combination exo-endocervical sampling device includes a shaft that includes a first end opposite a second end, and a combination exo-endocervical sampler configured to simultaneously collect endocervical cells and exocervical cells. The combination exo-endocervical sampler is coupled to the second end and includes a pair of opposing wings disposed transverse to the shaft and a brush extending from the wings along a central axis of the shaft. Each of the opposing wings includes a plurality of flexible loops configured to collect exocervical cells.Type: ApplicationFiled: June 14, 2010Publication date: September 30, 2010Inventor: Daniel Larkin
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Publication number: 20100241028Abstract: Tools for accessing tissue are described for use with a locatable guide of a navigation system. In preferred embodiments, said tools are attachable to a distal tip of a locatable guide, such that the location of the tool, preferably in six degrees of freedom, is known while the tool is being used.Type: ApplicationFiled: December 21, 2009Publication date: September 23, 2010Inventors: Jay Johnson, Tom Borillo, Paige Hastings, David J. McKinley
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Publication number: 20100234763Abstract: The present invention belongs to the veterinary field and will be applied to collect cytological, bacteriological and uterine secretion samples primarily from the uterine endometrium with the aim of detecting inflammations, including subclinical endometritis. The invention relates to a sampling device for obtaining cytological, bacteriological and smear samples from uterus of animals whose uterine cervix is difficult to penetrate. The device enables to obtain clean diagnostic material, which is important in obtaining high diagnostic accuracy. The device comprises a guiding tube and a rod extending through the guiding tube with a brush attached, and containing in addition a guiding tube cap that can be attached to a guiding tube with an inwards-facing cone, a Cytobrush ball and a rod-fixating screw located on the rear end of the guiding tube.Type: ApplicationFiled: June 7, 2007Publication date: September 16, 2010Inventors: Andres Valdmann, Merle Valdmann
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Patent number: 7785270Abstract: The present invention relates generally to devices and systems for detecting infection within catheters. In particular, the present invention provides catheter testing systems configured to sterilely collect a biological sample from the interior of a catheter for purposes of testing the biological sample (e.g., for the presence of fibrin, sepsis, etc.).Type: GrantFiled: March 2, 2007Date of Patent: August 31, 2010Assignee: CRS Medical Diagnostics, Inc.Inventors: Robert Brewer, Richard Julius, Michael Julius, Joseph Mattano, Kevin Davidson
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Patent number: 7767448Abstract: A PAP smear sampling device includes a PAP smear brush having a base with peripheral bristles and a central brush for sampling both cervical and endo cervical areas. A break away handle is provided for supporting the brush from enabling depositing of the brush into a specimen capsule.Type: GrantFiled: January 26, 2009Date of Patent: August 3, 2010Inventor: Peter A. K. Yong
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Patent number: 7762961Abstract: The invention relates to pressure generating units, in particular to pressure generating unit arranged in the hand piece of a vacuum biopsy device in the form of a sirynge (2). In said units, air intake is open by a piston when said piston (5) is in the rear position thereof in the space of a vacuumed cylinder (11) which is switched for generating a superpressure, thereby initiating the outflow of a tissue liquid by the air introduced into the space of the vacuumed cylinder. For this purpose, the space of the vacuumed cylinder is connected to the space of an atmosphere pressure cylinder (12) arranged behind the piston, by means of a connection line (15), and an absorbing element (14) is placed on the piston axis.Type: GrantFiled: March 29, 2004Date of Patent: July 27, 2010Assignee: C. R. Bard, Inc.Inventors: Norbert Heske, Thomas Heske
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Patent number: 7749173Abstract: A combination exo-endocervical sampling device includes a pair of opposing wings disposed transverse to a shaft, and a brush that extends from the wings along a central axis of the shaft. In this regard, each of the opposing wings includes a sampling surface having a staggered array of beads, and the brush includes a multiplicity of looped fibers, where each looped fiber includes a first closed end opposite a second closed end such that the closed ends extend transverse from the central axis of the shaft.Type: GrantFiled: October 26, 2006Date of Patent: July 6, 2010Inventor: Daniel Larkin
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Publication number: 20100125223Abstract: A cell sampling device is adapted for collecting the cells to be examined from the oral cavity or other organs for medical use. The device includes a handle and a brush having clusters of bristles in a rectangular shape connected to the end of the handle. In particular, the handle has a breaking portion formed at one side of the handle, two opposite sides of the handle or around the handle near the brush. The handle is turned to collect the cells to be examined. The breaking portion of the handle can be broken to dispose the unnecessary section of the handle. Thus, the device is able to be stored in a container for convenient storage of the cells to be examined.Type: ApplicationFiled: November 14, 2008Publication date: May 20, 2010Inventor: Cheng-Hsiung Roan
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Publication number: 20100076344Abstract: The present invention provides a speculum comprising a body (100), an opening (20), a first blade (2) pivotably secured to the body and a second blade (3) that is integral with the body. The blades are located at opposed sides of the opening. The first blade is pivotally secured with respect to the body by means of pivot pins. The first blade is movable between a first retracted position in which it lies adjacent to the second blade and a second extended position in which it is spaced apart from the second blade. A mechanism (5, 41) is also provided that is configured to move the first blade (2) from the first position to the second position. When the first blade is in the extended position, there is an inspection channel (20) formed that extends through the opening and between the blades. The mechanism for moving the first blade is preferably located substantially outside the periphery of the opening when the first blade is in the extended position.Type: ApplicationFiled: June 22, 2006Publication date: March 25, 2010Inventor: Maja Kecman
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Publication number: 20100069791Abstract: A tissue sampler for oral use has a wand that is sufficiently flexible to be inserted into the mouth of a patient without causing injury. A core is attached to the wand; the core is soft to avoid a likelihood of inducing a gag reflex in a patient when it is placed adjacent to an oropharynx of a patient. Bristles attached to the core so that when it is placed adjacent to the oropharynx of a patient, the bristles will acquire deep-seated cells in the crypts and grooves of the oropharynx. In operation, the patient preferably swallows which, especially because of the softness of the core, will force tissue onto the bristles. The bristles may be adapted to increase their tissue collecting capacity.Type: ApplicationFiled: September 10, 2009Publication date: March 18, 2010Inventor: Joel A. Ernster
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Publication number: 20090326414Abstract: A cytological sampling brush includes a manipulation handle (2) at one of end of which are provided a first portion in the form of exocol sampling brush (4) and a second portion in the form of endocol sampling swab (5) at the center of the first portion in brush (4) form. This brush is characterized in that the second portion in swab (5) form is attached at the end of the handle (2) and is removable from the first portion by sliding in a hole (6) of the first portion in brush (4) form, provided with elements (7) for retaining cells for collecting cells from the second portion in swab (5) form, during retraction of the first portion in brush (4) form.Type: ApplicationFiled: July 4, 2007Publication date: December 31, 2009Applicant: NOVACYTInventor: Eric Peltier
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Publication number: 20090299222Abstract: A guide wire treatment tool includes an operation wire having a treatment part on the head thereof, and a sheath through which the operation wire is slidably inserted. A head chip having a through-hole, through which a guide wire is inserted, is provided on a head part of the treatment part, and the treatment part and the head chip are coupled via a coupling part so as to be relatively rotatable around an axis which extends along the length of the operation wire.Type: ApplicationFiled: March 1, 2006Publication date: December 3, 2009Inventor: Yutaka Yanuma
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Patent number: 7625346Abstract: Transbronchial needle aspiration (TBNA) device. In one embodiment, the device comprises a handle and a flexible catheter, the handle having a bore, the proximal end of the catheter being fixed within the handle bore. A protective tubular hub having a flared distal end is press-fit coaxially within the distal end of the catheter, the distal end of the catheter being sealed around the distal end of the hub so as to define a distal opening. A hollow needle having a sharp tip at its distal end is disposed within the catheter, the needle tip being sized for insertion through the distal opening of the catheter. The distal end of a flexible wire is coupled to the proximal end of the needle, the proximal end of the wire extending through the handle bore and coupled to a button slide accessible through a slot in the handle.Type: GrantFiled: May 30, 2003Date of Patent: December 1, 2009Assignee: Boston Scientific Scimed, Inc.Inventors: Sergey S. Grigoryants, Luis J. Maseda
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Publication number: 20090275859Abstract: A kit for collecting specimen includes a tubular member sized for placement in the vaginal canal, a sampling member configured for receipt within the tubular member, and a container of collection medium suitable for preserving and transporting human tissue cells and related tissue secretions. The tubular member has a wall defining a longitudinal through channel having a central axis. The tubular member defines an opening at a distal end oriented at an oblique angle to the central axis with a first section of the wall extending distally of a distal end of a second section of the wall. At least a portion of the first section of the wall flares distally to an enlarged outer diameter at the opening.Type: ApplicationFiled: May 6, 2009Publication date: November 5, 2009Applicant: Quaternion Investments LLCInventor: Nicholas H. Kim
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Patent number: 7611473Abstract: Devices and methods are provided for extracting and macerating tissue, and optionally for depositing the tissue onto a tissue scaffold. The device generally includes an outer tube having a substantially open distal end that is adapted to be placed on and preferably to form a seal with a tissue surface, and a shaft rotatably disposed within the outer tube and movable between a first, proximal position in which the shaft is fully disposed within the outer tube, and a second, distal position in which a portion of a distal end of the shaft extends through the opening in the distal end of the outer tube. The device also includes a tissue harvesting tip formed on the distal end of the shaft that is effective to excise a tissue sample when the shaft is moved to the distal position, and a cutting member that is coupled to the shaft at a position proximal to the tissue harvesting tip. The cutting member is effective to macerate a tissue sample excised by the tissue harvesting tip.Type: GrantFiled: September 11, 2003Date of Patent: November 3, 2009Assignee: Ethicon, Inc.Inventors: Robert Boock, Nathan S. Cauldwell, Keith M. Orr
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Publication number: 20090240164Abstract: A tissue sampling device is provided. The tissue sampling device includes a single wire spirally wrapped at its half-length creating the backbone of the brush. This wire is partially covered in a hollow flexible tube, which is fixed in place. Located along the distal end portion of the wire is a brush with bristles that are used for collecting a tissue sample. The bristles are tapered from the distal end of the wire. An atraumatic bulb is located on the extreme distal end of the wire to protect the tissue during insertion. A handle is located on the extreme proximal end of the flexible tube. The flexible tube is contained within a sheath, wherein the sheath can be moved along the flexible tube to the distal end, to the atraumatic bulb, to cover the brush during insertion and after tissue collection. The sheath is moved back toward the proximal end of the flexible tube after the device has been inserted to the proper collection depth, exposing the brush and allowing for collection of a tissue sample.Type: ApplicationFiled: March 18, 2008Publication date: September 24, 2009Inventor: Alexandra Jean Gillespie
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Publication number: 20090156962Abstract: A PAP smear sampling device includes a PAP smear brush having a base with peripheral bristles and a central brush for sampling both cervical and endo cervical areas. A break away handle is provided for supporting the brush from enabling depositing of the brush into a specimen capsule.Type: ApplicationFiled: January 26, 2009Publication date: June 18, 2009Inventor: PETER A.K. YONG
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Patent number: 7517323Abstract: A mucous gathering device, comprising an elongated rotatable stem having a longitudinal axis, and a rotary headpiece carried at an end of the stem for angular flexing as the stem rotates, the headpiece having a face sized for presentation to the cervix entrance as the head rotates about an axis angled relative to the stem, the face having associated flexible means for gathering and retaining mucous proximate the cervix as the headpiece rotates, and a flexible rotary probe carried by the headpiece, the probe projecting forwardly and centrally relative to associated means and defining edges spaced apart to gather and propel mucous toward the headpiece in response to probe rotation in an opening defined by the cervix.Type: GrantFiled: October 19, 2006Date of Patent: April 14, 2009Inventor: Raymond C. Ng
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Publication number: 20090062691Abstract: A device includes a tubular member sized for placement in the vaginal canal. The tubular member has a wall defining a longitudinal through-channel having a central axis, and an opening at a distal end oriented at an oblique angle to the central axis such that a first section of the wall extends distally of a distal end of a second section of the wall. The first section flares outwardly by 13-30 mm to an enlarged outer diameter at the opening. The oblique angle is 20-65°, and the first section of the wall extends distally of the distal end of the second section of the wall by 20-60 mm.Type: ApplicationFiled: August 29, 2007Publication date: March 5, 2009Applicant: Quaternion Investments LLCInventor: Nicholas H. Kim
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Publication number: 20090062690Abstract: A kit for collecting specimen includes a tubular member sized for placement in the vaginal canal, a sampling member configured for receipt within the tubular member, and a container of collection medium suitable for preserving and transporting human tissue cells and related tissue secretions. The tubular member has a wall defining a longitudinal through channel having a central axis. The tubular member defines an opening at a distal end oriented at an oblique angle to the central axis with a first section of the wall extending distally of a distal end of a second section of the wall. At least a portion of the first section of the wall flares distally to an enlarged outer diameter at the opening.Type: ApplicationFiled: August 29, 2007Publication date: March 5, 2009Applicant: Quaternion Investments LLCInventor: Nicholas H. Kim
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Publication number: 20090018469Abstract: The present invention is related to an endoscopic treatment tool which is inserted to a body cavity endoscopically including a wire, a surgical section which is disposed on a first end of the wire and used for treatment inside the body cavity, and an operator section which is disposed on the second end of the wire and moves in conjunction with the wire so as to rotate by a rotary operation; and the movement of the operator section in conjunction with the wire is released upon exerting more than a predetermined torsional load on the wire.Type: ApplicationFiled: July 10, 2007Publication date: January 15, 2009Applicant: OLYMPUS MEDICAL SYSTEMS CORP.Inventors: Yutaka YANUMA, Takashi NAGATA, Tsukasa Kobayashi, Isao Sasaki
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Publication number: 20090012424Abstract: A device for removing and smearing cells for a cytological examination with a handle at whose front end a device for the collection of the cells is arranged. The device provides an economical solution for cell collection and a reliable solution for smearing on a microscope slide. The device is embodied as a cone tapering towards the front in which a stabilizing device acting on a longitudinal extension of the cone is arranged.Type: ApplicationFiled: March 3, 2005Publication date: January 8, 2009Applicant: GEORG-AUGUST-UNIVERSITAET GOETTINGENInventors: Abdolhamid Huschmand Nia, Reihold Wegener
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Publication number: 20080294067Abstract: The present invention relates to a brush (1) for cleaning or sampling body tissue. The brush (1) comprises a support (2) that is provided with at least one row (3) of brush hairs (5) as well as one second row (4) of brush hairs (16). The first and second rows are mutually parallel and are situated next to one another. Each brush hair (5,6) has a proximal end (7) facing the support (2) and a distal end (9) facing away from the support (2). The first row (3) of brush hairs (5) comprises a strip (30) that extends in the longitudinal direction of the first row (3) and a longitudinal side (32) of which is fixed to the support (2). The proximal ends (7) of the brush hairs (5) in the first row (3) are fixed to the other longitudinal side (34) of the strip (30).Type: ApplicationFiled: December 22, 2005Publication date: November 27, 2008Applicant: MDZ BEHEER B.V.Inventor: Meindert Durk Zwart
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Publication number: 20080262384Abstract: The present invention provides multi-parameter analysis methods for determining the presence or absence of pre-cancerous or cancerous cells in a cervical sample and for screening cervical abnormality in a cervical sample. The invention also provides an apparatus and automated methods for screening cervical abnormality in a sample. The invention further provides a sampling device and a sample collection assembly for collecting cell samples, including cervical samples.Type: ApplicationFiled: November 4, 2005Publication date: October 23, 2008Applicant: SOUTHWEST RESEARCH INSTITUTEInventors: Urs G. Wiederkehr, Jian Ling
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Patent number: 7413551Abstract: The device consists of a shaft with a detachable brush head. The brush head is a new design incorporating the utility of an expandable self adjusting area that yields a complete sample of the endocervix and exocervix regardless of varying individual anatomy. The brush head has protrusions disposed at strategic positions with flat surface collection areas. A ledge with protrusions samples the exocervical area and a middle portion samples the endocervical area. The middle portion automatically elongates from approximately 2 cm to 5.5 cm as to adjust to individual anatomies as the brush head is inserted into the cervical canal. The brush head is matched to a special collection container that permits the brush head to be detached and deposited into the container without the handling of the brush/head area. The special conical insert within the container automatically orients brush head for passage through horizontal slot at bottom of insert without operator's need to manually align.Type: GrantFiled: September 27, 2005Date of Patent: August 19, 2008Inventors: David Decker, Thomas DeAngelis
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Publication number: 20080188769Abstract: A foldable brush self-sampling device for collecting of cell specimens from a body cavity, such as cervix, endometrium, rectum, nasal cavity and fauces, for diagnostic purposes, allows a user to collect cell specimens in the privacy of home. The device includes a sheath and a brush bar. The brush bar would fold into the sheath, which is with smaller diameter. The user inserts the sheath into the cavity easily and pushes the brush bar to expose the brush elements. After insertion of the sheath and push of the brush bar, the brush bar is rotated to obtain the specimen from the body cavity and then retracted in order to return the sheath.Type: ApplicationFiled: February 7, 2007Publication date: August 7, 2008Inventor: Li-Cheng LU
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Publication number: 20080188757Abstract: The present invention relates to a portable device which analyses cervical tissue using two simultaneous measurements, namely an electrical measurement and an optical measurement. The aforementioned device examines different areas of cervical tissue, taking electrical measurements from same in different frequency ranges and optical measurements in three different wavelengths. Once the measurements have been obtained, they are processed by a configurable device or microcontroller in accordance with mathematical formulae obtained from multiple measurements taken from healthy and cancerous tissues. Three possible responses can be obtained from the processing of the measurements: healthy tissue, cancerous tissue or the presence of human papilloma virus. The inventive device can be used as a self-detection device since it is equipped with an attachment for positioning same upon detection of proximity to the cervix in order to take a correct measurement.Type: ApplicationFiled: February 20, 2006Publication date: August 7, 2008Applicant: Ave Eugenio Garza Sada #2501 Sur, Col. TecnologicInventors: Noel Leon Rovira, Arturo Hernandez Fuentes, Jose Antonio Viornery Escorza, Norma Frida Roffe Samaniego
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Patent number: 7384401Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.Type: GrantFiled: July 12, 2004Date of Patent: June 10, 2008Assignee: Lifeline Biotechnologies, Inc.Inventors: William H. Reeves, Jonathan Reeves, Louis Keith
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Publication number: 20080077046Abstract: Disclosed herein is a cell collection device, comprising a shaft having a proximal portion and a distal portion, each portion having a proximal end and a distal end; a detachable joint between said proximal portion and said distal portion; and a cell collection portion at said distal end of said distal portion; whereby when said proximal portion and said distal portion are detached at said detachable joint, said proximal end of said distal portion is attachable to a vial cap.Type: ApplicationFiled: August 24, 2006Publication date: March 27, 2008Applicant: Cytyc CorporationInventor: Larry Burg
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Patent number: 7344506Abstract: This invention relates generally to medical devices, and more particularly, an apparatus and method for collecting cells or tissue samples from the cervix of a patient for medical testing.Type: GrantFiled: March 20, 2007Date of Patent: March 18, 2008Assignee: Cytyc CorporationInventor: Steven A. Scampini
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Publication number: 20070282222Abstract: A sexually transmitted infection (STI) sampling device includes an elongated shaft that defines a first end separated from a second end, and an absorbent sampler coupled to one of the first and second ends. The absorbent sampler includes an absorbent core disposed on a longitudinal axis of the elongated shaft, and a plurality of fibers extending from the absorbent core. The plurality of fibers is configured to exfoliate and capture cells from a tissue surface of a patient, and the absorbent core is configured to absorb exfoliated cells not captured by the fibers.Type: ApplicationFiled: April 24, 2007Publication date: December 6, 2007Inventor: Daniel Larkin
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Patent number: 7144377Abstract: A personal cervical cell collector that will allow a female patient to collect cervical cells in the privacy of her home, having a proximal end and a distal end that has a position unit formed therein, a guide assembly having a head formed in a front end thereof and exposing from the outer shell and a sampling assembly having a sampling unit. The guide assembly mounted in the outer shell is guiding the personal cervical cell collector to insert into the vagina guided by the head, and the head touches the woman's cervix and the position unit locks with a peripheral of the cervix for achieving position effect. Continuously, the guide assembly is taken out and the sampling assembly is mounted and then the sampling unit is adjusted to a direction corresponding to the cervix so that collecting is proceeding.Type: GrantFiled: December 28, 2004Date of Patent: December 5, 2006Inventor: Li-Cheng Lu
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Patent number: 7108661Abstract: A method and apparatus for obtaining esophageal cells for diagnostic purposes. A distal end of a support body is inserted in a patient's stomach via the esophagus and mouth. A balloon at the distal support body end is inflated. The support body is withdrawn until the balloon engages the sphincter. A support body location is marked that is a predetermined distance from the patient's dental arch. The balloon is deflated and the support body is withdrawn so that the marked location is adjacent the patient's dental arch. The support body is withdrawn a second predetermined distance and a second support body location is marked. A cell collecting element is deployed from within the distal end of the support body. The support body is reciprocated with the cell collecting element deployed so that cells from the esophagus are deposited on the cell collecting element.Type: GrantFiled: May 7, 2001Date of Patent: September 19, 2006Assignee: United States Endoscopy Group, Inc.Inventors: Dean J. Secrest, Marlin Younker
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Patent number: 7087028Abstract: A cervical sampling system for collecting a cervical sample for using a Pap test. The cervical sampling system includes an insertion tube with an insertion position indicator, and an introduction guide member that guides the insertion tube into a vaginal cavity. The vaginal insertion tube includes an insertion depth indicator to allow the user to determine the appropriate depth to insert the tube. A cervical sampler is positioned within the vaginal insertion tube and extends into the vaginal cavity to collect samples. The insertion tube and cervical sampler include signaling members that cooperate to indicate to the user when the cervical sample has been rotated through a complete revolution. After the cervical sample has been collected, an ethanol based fixative is applied onto the collecting member before it is forwarded to a lab for slide preparation.Type: GrantFiled: September 24, 2001Date of Patent: August 8, 2006Assignee: R&G Medical and Development Corp.Inventor: Robert F. Sak
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Patent number: 7081097Abstract: Apparatus and methods for obtaining biopsy samples using an endoscope assembly are disclosed. In one embodiment, an assembly adapted for use with an endoscopic insertion tube includes a sheath having a body portion adapted to at least partially encapsulate a distal portion of the insertion tube, and a biopsy sampling device attached to the sheath and including a collection member proximate an end of the body portion. The biopsy sampling device may be attached to the body portion of the sheath, or alternately, may be attached to an enclosed distal end of the sheath. The assembly may also include a cover attached to the sheath and positionable proximate the biopsy sampling device. An actuation member may be attached to the cover and may extend along the sheath, allowing the operator to actuate the cover between a covered position and a collecting position.Type: GrantFiled: January 4, 2002Date of Patent: July 25, 2006Assignee: Vision Sciences, Inc.Inventors: Stephen Martone, Katsumi Oneda
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Patent number: 7056293Abstract: An apparatus and method of use thereof for identifying and monitoring women at risk of developing OSE-derived carcinomas is provided. The apparatus includes an introducer needle configured to be capable of insertion into a female such that a terminal end of the needle is positioned adjacent an ovary of the female, a microendoscope having an optic fiber which is operably insertable into the needle in a manner to enable an image of the ovary to be obtained therethrough, and a tissue removing member operably co-insertable into the needle with the optic fiber therein to enable removal of ovarian tissue cells with minimal deleterious effect to the ovary.Type: GrantFiled: December 24, 2001Date of Patent: June 6, 2006Assignee: LifeLine Biotechnologies, IncInventors: William H. Reeves, Jonathan Reeves, Louis Keith
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Patent number: 7004913Abstract: A retractable brush structure is attached to a cylindrical rigid rod which in the closed position passes through a channel in an endoscope. After the brush passes through the endoscope, the brush moves against the tissue in order to remove cells from an area under examination. The brush is withdrawn from the endoscope and sample tissue is removed from said brush for examination after it is withdrawn from the endoscope.Type: GrantFiled: January 12, 2004Date of Patent: February 28, 2006Assignee: CDx Laboratories, Inc.Inventors: Mark Rutenberg, Stephen Frist
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Patent number: 6846292Abstract: A biopsy needle and method of using the same. The biopsy needle includes a pair of articulating members that can be moved between a retracted position where the articulating members are contained within the biopsy needle and an extended position where the articulating members extend outwardly from the distal end of the biopsy needle into the pleural cavity of a patient. Once extended, the articulating members have operative surfaces that contact the parietal pleura of the patient such that a biopsy sample can be obtained as the operative surfaces are moved in contact with the parietal pleura. The operative surfaces may be a brush blade or a knife blade. A passageway within the interior of the biopsy needle allows removal of fluids from the patient.Type: GrantFiled: February 19, 2002Date of Patent: January 25, 2005Inventor: Mohamed Bakry
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Patent number: 6840911Abstract: An apparatus and method is provided for collecting a DNA sample from the skin and/or from the oral cavity of a subject, the apparatus comprising a handle mounted absorbent layer supported by a resilient layer and bar codes for association of the sample with identification and evidence documents a storage system is provided to allow sample location using a bar code identifier which avoids removal of the device from storage and avoids disturbing the collected sample.Type: GrantFiled: August 5, 2002Date of Patent: January 11, 2005Inventor: Jangbir S. Sangha
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Publication number: 20040260199Abstract: Differing cytology device apparatuses, and methods for their use, are provided for collecting cytology samples from within a mammalian body. The apparatuses and methods disclosed are minimally invasive. Some of the apparatuses include a needle having an inner lumen extending from a proximal to a distal end. A stylet, having a proximal end and a distal end, is adapted to be inserted into the inner lumen of the needle to plug the inner lumen while a cytology sample is cut in order to prevent contamination within the needle. The distal end of the stylet may be sharp, and may be adapted to extend beyond the distal end of the needle to cut a cytology sample. Also included is a cytology collection device which is adapted to be inserted into the inner lumen of the needle when the stylet is withdrawn from the inner lumen of the needle.Type: ApplicationFiled: December 9, 2003Publication date: December 23, 2004Applicants: Wilson-Cook Medical, Inc., Cook Ireland LimitedInventors: David M. Hardia, John Mugan, Charles J. Lightdale, Courtney Leigh Rawlings
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Publication number: 20040260201Abstract: A cytology brush suitable for conducting a brushing biopsy within a mammary duct of a human patient is provided. The cytology brush comprises a handle and a detachable or releasable brush. After a brushing biopsy the brush end can be released and retained in the collection vessel. Optionally, a dispensable biopsy site marker is carried by the brush and can be left in place after biopsy.Type: ApplicationFiled: June 23, 2003Publication date: December 23, 2004Inventor: Richard L. Mueller
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Publication number: 20040236247Abstract: A device for scrapping and collecting the tissue from body cavities like endocervix to perform tissue biopsy procedures such as endocervical curettage. The instrument includes a screw shape scraper and a brush mounted to the either ends of an elongated handle shaft. The scraper has a screw shape with blunt end mounted on one end of a shaft. The other end of the shaft has a brush with brissels to facilitate the trapping and collection of the tissue. The device is disposable and made of plastic as much as possible.Type: ApplicationFiled: May 24, 2003Publication date: November 25, 2004Inventor: Syed Rizvi
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Publication number: 20040181170Abstract: A device is provided for self-sampling a body cavity, in particular the cervix, and a method is provided to use the device to obtain samples from the cervix for testing for the presence of human papillomavirus (HPV) DNA. The device includes elongated flexible bristles attached to a handle to form a mop-like sampling member. The sampling member is rotated to mop the cervix and obtain a sample of cervical cells on the elongated bristles. The sampling device is then withdrawn from the vaginal cavity and the sample is sent for analysis.Type: ApplicationFiled: March 24, 2004Publication date: September 16, 2004Inventor: Ronald M. Wallach
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Publication number: 20040116827Abstract: A disposable device for cervical and endocervical cell collection by a subject: female patient, doctor, other health care practitioner (nurse, paramedic, etc.) or any trained person. The object of the present invention is to provide effective methods and apparatus for easy cervical cancer screening which can be administered without the need for direct cervical observation, for health care facilities or without the assistance of health professionals. The present device is easy and inexpensive to manufacture, as well as easy to use and can therefore be made widely available to the consuming public. It may be designed for retail sale as well as mass distribution for mass prevention campaigns (in hospitals, developing countries) This device includes a plastic tube. The distal end of the tube is closed by a very thin membrane (plastic or other similar material). This tube contains a plastic stick with a proximal enlargement for manipulation by the subject.Type: ApplicationFiled: November 21, 2003Publication date: June 17, 2004Inventor: Osvaldo Antonio Tiberio
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Patent number: 6740049Abstract: A device is provided for self-sampling a body cavity, in particular the cervix, and a method is provided to use the device to obtain samples from the cervix for testing for the presence of human papillomavirus (HPV) DNA. The device includes elongated flexible bristles attached to a handle to form a mop-like sampling member. The sampling member is rotated to mop the cervix and obtain a sample of cervical cells on the elongated bristles. The sampling device is then withdrawn from the vaginal cavity and the sample is sent for analysis.Type: GrantFiled: March 14, 2002Date of Patent: May 25, 2004Inventor: Ronald M. Wallach