Abstract: Monitoring vital parameters of a wearer of a compression garment by analyzing a pressure signal waveform indicative of a fluid pressure in an inflatable and deflatable bladder of the compression garment. Analyzing the pressure signal waveform for an oscillating amplitude as a function of time and/or a representation of a pulse of the wearer provides an indication of blood pressure of the wearer.

Abstract: A device for providing tactile stimulation of a subject via a pulse of compressible fluid, typically for medical diagnostic and therapeutic applications. The device preferably includes a high pressure fluid source and a low pressure fluid source. A pressure valve selectively connects the pressure sources to an outlet conduit. The outlet conduit includes an applicator for directing pulses against the skin of a subject. The pulses may be applied via one applicator or a plurality of applicators, and may be applied in one pattern or several patterns at various application sites. A method of providing tactile stimulation is also disclosed.

Abstract: A pressure therapy device includes a pressure chamber, an inflatable padding, a seal, and a positioning mechanism. The pressure chamber has an opening arranged for admitting the inflatable padding and a limb of a user. The inflatable padding is inflatable to enclose and fix the limb in position. The seal covers the opening, including the inflatable padding and the limb to seal the pressure chamber from ambient atmospheric pressure. A pump unit is provided to generate a non-atmospheric pressure within the pressure chamber and includes a first valve system and a piston with safety release features for preventing unsafe pressure levels.

Abstract: A pressure therapy device includes a pressure chamber, an inflatable padding, a seal, and a positioning mechanism. The pressure chamber has an opening arranged for admitting the inflatable padding and a limb of a user. The inflatable padding is inflatable to enclose and fix the limb in position. The seal covers the opening, including the inflatable padding and the limb to seal the pressure chamber from ambient atmospheric pressure. A pump unit is provided to generate a non-atmospheric pressure within the pressure chamber and includes a first valve system and a piston with safety release features for preventing unsafe pressure levels.

Abstract: A method for external ear canal pressure regulation to alleviate one or more symptoms associated with a disorder or treat one or more disorders, the method including providing a fluid transfer device which generates a fluid flow of a fluid through an earplug, the earplug having an earplug external surface configured to sealably engage an external ear canal wall as a barrier between an external ear canal pressure and an ambient pressure; sealably engaging the earplug of the fluid transfer device with the external ear canal wall as the barrier between the external ear canal pressure and the ambient pressure; and operating the fluid transfer device to generate the fluid flow of the fluid through the earplug to achieve an external ear canal pressure differential between the external ear canal pressure and the ambient pressure effective to alleviate a disorder symptom or treat a disorder.

Abstract: The invention disrupts the paradigm of the side entrance within the field of saunas, steam rooms and therapeutic chambers. The invention reorients the entrance from a door in the side of a therapeutic chamber, as is the situation in the prior art, and places the point of ingress and egress to the bottom or floor of the chamber. Without a side entry door, much less heat is lost when individuals enter and exit the chamber. Furthermore, this invention creates the opportunity for 360 degree seating in steam rooms and saunas, which is exemplified in the embodiment of the prototype named Steam Egg, which is a ten and a half foot tall freestanding egg shaped, mirror covered, steam room that is entered through a hole in the bottom, hovering 33.5 inches off the ground stabilized on three steel legs.

Abstract: A device for providing tactile stimulation of a subject via a pulse of compressible fluid, typically for medical diagnostic and therapeutic applications. The device preferably includes a high pressure fluid source and a low pressure fluid source. A pressure valve selectively connects the pressure sources to an outlet conduit. The outlet conduit includes an applicator for directing pulses against the skin of a subject. The pulses may be applied via one applicator or a plurality of applicators, and may be applied in one pattern or several patterns at various application sites. A method of providing tactile stimulation is also disclosed.

Abstract: Provided is a living body stimulator capable of not only realizing a low power consumption and a light weight, but also improving the degree of freedom of an outer shape thereof. Each of airbags (3-1) to (3-3) is individually provided with one of air pumps (1-1) to (1-3) and one of air tanks (2-1) to (2-3). As for each of pressurization units (41-1) to (41-3), a pressurized air is supplied from one air pump (1-1) to one airbag (3-1) through one air tank (2-1). A control unit (51) is configured to individually control each of the pressurization units (41-1) to (41-3). Therefore, it is possible to downsize the air pumps (1-1) to (1-3) and air tanks (2-1) to (2-3).

Abstract: An intermittent pneumatic compression system provides exhaust between a wrap and patient's leg, avoids tubes and is operable on a conventional battery. The system allows true portability while improving patient discomfort, reducing fall risks, and providing desired therapeutic and prophylactic compression.

Abstract: An assembly for the treatment of wounds comprising a device for generating a plasma, or an excited gas or gas mixture, respectively. A covering is used to cover a wound area. A first conduit connects the device and the covering and a second conduit connects the covering and a pump. The device is arranged within a housing comprising an opening. The device comprises a piezoelectric transformer having a high-voltage end for generating the plasma, and is arranged within the housing such that the high-voltage end is directed towards the opening. The plasma or the excited gas or gas mixture, respectively, is generated in a region of the opening of the housing. A wound cover comprising a means for guiding the plasma across the wound area is arranged between the covering and the wound area.

Abstract: A wound therapy device and a kit for same with a housing material, a gasket disposed around at least a portion of the housing material, a non-woven absorption material, and a port. The gasket is sized and configured such that at least a first portion of the gasket will be adhered to a second portion of the gasket upon a folding of the housing material. A method of using a wound therapy device.

Abstract: A therapeutic hand exercise device includes one or more pliant sleeves (5) for attachment to one or more digits of a human hand, a chamber (4) provided in at least a dorsal region of the or each pliant sleeve (5), a liquid inlet to the chamber and a pump (3) for supplying pressurized liquid to the or each chamber. Each pliant sleeve (5) is movable between a relaxed state and a stiffened state in which the pliant sleeve forms a substantially rigid elongate member for holding a finger disposed within the sleeve in an extended position. A resilient member (6) is fitted to the palmar side of each pliant sleeve which returns the finger to a state of contracture.

Abstract: An apparatus for treatment of fungal infections and/or other foot skin disorders, comprises a shoe-type housing having a substantially hollow interior forming a treatment chamber, a supporting platform disposed within the hollow chamber; so that a foot of a patient positioned within the treatment chamber is supported by the platform, so that nails are disposed at the lower level of the front part of the chamber, whereas the heel of the foot is being elevated a rear part thereof. A delivery and control assembly for the aqueous solution is provided. At least one light delivery arrangement is disposed within or in the vicinity of the treatment chamber.

Abstract: An adjustable personal treatment apparatus that is usable by women of all sizes to enable them to enjoy, without harm, the full healthful benefits of proper and necessary massage and therapy. More particularly, the apparatus permits the proper pressure to be applied to a female patient during massage, or therapeutic treatment, without causing discomfort and possible damage to breast tissue or breast implants.

Abstract: This invention relates to an exercise device (1) and more particularly to an exercise device of the type that allows the user of the exercise device to exercise with part of their body in a negative pressure environment. These devices are becoming increasingly popular however the known devices are usually bulky, difficult to transport, difficult to install and difficult to maintain. The present invention provides a construction of exercise device that will enable the device to be transported and installed in a more efficient manner by providing the casing (3), in particular, in a number or pieces (21, 23) that can be connected together easily and quickly on site. The casing will still be sufficiently air tight. Furthermore, the construction of the present invention permits easier access to the interior of the casing (3) for cleaning/servicing purposes thereby simplifying cleaning and repair significantly.

Abstract: A steam physiotherapy apparatus includes an open-topped physiotherapy chamber having a door, a steam generating unit, and a steam pipe for conveying generated steam into the physiotherapy chamber. Tourmaline tiles are attached to an inner surface of the physiotherapy chamber, a steam inlet pipe is provided on a bottom of the physiotherapy chamber to communicate with the steam pipe, and a steam flow guide plate is placed on the steam inlet pipe. The steam inlet pipe has two diametrically opposite steam outlets directed to two opposite directions, such that the steam flowing out of the two steam outlets forms a swirl that moves upward along the inner surface of the physiotherapy chamber to heat the tourmaline tiles. The heated tourmaline tiles release far infrared rays and negative ions that help reducing reactive oxygen species and free radicals in the user's body and help the user to give off deep-layer sweat.

Abstract: Apparatuses, systems, and methods for applying reduced pressure to a tissue site on a foot are provided. An apparatus may include an insole and a tissue contacting surface covering at least a portion of the insole. At least one portion of the tissue contacting surface is removable to form a void. The apparatus may also include a reduced-pressure interface for receiving reduced pressure from a reduced-pressure source, and at least one flow channel fluidly coupled to the reduced-pressure interface and the void.

Abstract: Provided is an apparatus that includes a nerve conduit and a nested manifold for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit and nested manifold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

Abstract: Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

Abstract: A system is provided by applying pressure to a portion of a body of an individual in a chamber having an aperture along a vertical axis for receiving the portion of the body of the individual. A pressure sensor is coupled to the chamber for measuring a pressure inside the chamber. A negative feedback control system, calibrates, adjusts and maintains the pressure inside the chamber.

Abstract: Systems and methods for affecting metabolism, such as the treatment of metabolic syndrome are disclosed. A method for treating metabolic syndrome can include one or more of the steps including identifying a region of the patient comprising glabrous tissue; positioning the region of the patient comprising glabrous tissue into an enclosed chamber; adjusting the relative humidity of the enclosed chamber sufficient to create a physiologic metabolic effect; and activating a convection fan within the chamber to promote heat transfer from the glabrous tissue. The method need not involve altering the temperature within the enclosed chamber.

Abstract: A system is provided by applying pressure to a portion of a body of an individual in a chamber having an aperture along a vertical axis for receiving the portion of the body of the individual. A pressure sensor is coupled to the chamber for measuring a pressure inside the chamber. A negative feedback control system, calibrates, adjusts and maintains the pressure inside the chamber.

Abstract: An embodiment of a system for treating sleep apnea includes a collar, a pump, and a motor. The collar has a vacuum surface and has a sealing surface that is configured to form a seal with a region of a neck of a subject having an airway. The pump is secured to the collar, and is configured to maintain the airway open by drawing a vacuum between the vacuum surface of the collar and a region of a throat of the subject. And the motor is secured to the collar and is configured to drive the pump. As compared to existing systems (e.g., a Continuous Positive Airway Pressure (CPAP) system) for treating sleep apnea, the above-described system may be more portable, more comfortable, may be less likely to require adjustment while a subject using the system is asleep, and, therefore, may be less likely to awaken the subject.

Abstract: A system can perform the following procedure as part of a plan to treat sleep apnea, according to an embodiment. The system monitors a degree to which an airway of a subject is open, and monitors a condition that is related to the degree to which the airway is open. The system also correlates the condition to the degree to which the airway is open, and generates a data structure that represents the correlation between the condition and the degree to which the airway is open. This system can allow a sleep-apnea-treatment system to operate in a closed-loop mode, i.e., to monitor a level of sleep apnea in a subject by monitoring the correlated condition, and to treat the subject in a manner that the treatment system deems appropriate for the level of sleep apnea that the treatment system determines that the subject is experiencing.

Abstract: A method of selecting and using a compression garment is disclosed. The method may include selecting a garment comprising a compression sleeve including a proximal end and a distal end. The compression sleeve may comprise material having one of short-stretch function and inelastic function. The method may include donning the garment by inserting a limb of an animal or human through an opening in the proximal end and positioning the compression sleeve such that the material extends over at least a portion of a muscle mass of the limb. When the muscle mass is activated, the compression sleeve may augment the venous muscle return produced by the muscle mass.

Abstract: Provided is an apparatus that includes a nerve conduit and a nested manifold for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit and nested manifold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

Abstract: A controller is operable to selectively supply gas to, and evacuate gas from, regions of a hyperbaric wound treatment chamber. The controller operates to inflate a passage or rib of the device to provide that the device is made sufficiently rigid for inserting a limb therethrough, and inflate an inflatable cuff to create a seal against the limb. The controller also operates to evacuate ambient air trapped within the chamber, and optionally partially evacuate the passage or rib, after the seal is created by the inflatable cuff, and then introduce oxygen into the chamber, and optionally inflate the passage or rib. The cuff, when inflated and creating a seal against a limb, optionally is at least partially within the chamber, and the treatment gas is supplied to the chamber to maintain the seal of the cuff against the limb.

Abstract: Apparatus and methods are provided for treating a human condition by providing an appendage chamber having a thermal exchange member. A vacuum may be applied to the appendage chamber to maintain vasodilation of an appendage when placed within the appendage chamber. The appendage may be heated or cooled at the thermal exchange member for therapeutic application of thermal energy to treat a number of circulatory, neurological, lymphatic, or endocrinal maladies.

Abstract: An adjustable massage apparatus, whose massage effect is based on the suction effect created in association with the treatment head, the treatment head of the apparatus including a surface which comes in contact with the skin, a frame, and in connection with this surface a low-pressure chamber and a low-pressure hose in connection with the low-pressure chamber for created low-pressure suction in order to lift the skin tissue. The apparatus is mainly characterized in that a valve is arranged in connection with the low-pressure hose for adjusting the low-pressure suction created in the low-pressure chamber so that the pressure in the low-pressure chamber is oscillating between an upper limit and a lower limit.

Abstract: Apparatus and methods are provided for applying negative pressure to tissues of a patient that are transmitted to the vertebral venous system of the patient and thereby lowering intracranial pressure. Intracranial pressure is thus lowered easily without increasing the work of breathing, without needing to be intubated, and without breathing through a valve in patients with elevated increased intracranial pressure.

Abstract: An apparatus for mechanically ventilating a patient is provided to have two separate components movably arranged with respect to one another within a flexible, air-tight covering fit about the torso of a patient. When the components move away from one another within the air-tight covering, negative pressure is generated which causes the patient to draw air into the lungs. Conversely, when the components stop moving away from one another within the air-tight covering, the patient's natural exhalation recoil takes over to allow the patient to expel the air from within the patient's lungs. A ventilator for helping a patient such as a premature infant breathe when placed in a chamber, is also provided.

Abstract: Massage appliance comprising a hollow body (10) delimiting an internal volume connected (7) to a suction source so as to form a suction chamber by bearing with its edge (2) on the skin, said hollow body (10) enclosing at least one internal bearing element able to act by compression on the skin, when the internal volume is at an under pressure; it has an actuator (11) for exerting on the skin, by way of at least one internal bearing element, a force F applied to said element(s) in a continuous manner, at least one of the internal bearing elements thus acting on the skin with a localized continuous compression.

Abstract: Described herein are various embodiments of differential air pressure systems and methods of using such systems. The differential air pressure system may comprise a chamber configured to receive a portion of a user's lower body and to create an air pressure differential upon the user's body. The differential air pressure system may further comprise a user seal that seal the pressure chamber to the user's body. The height of the user seal may be adjusted to accommodate users with various body heights.

Abstract: Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

Abstract: Methods and devices for manipulating the thermoregulatory status of a mammal are provided. In the subject methods, thermal energy is transferred between the environment and both of the thoracic/abdominal core body and head of the mammal. In general, thermal energy transfer between thoracic/abdominal core body and the environment occurs under negative pressure conditions. The subject methods and devices can be used to increase the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is introduced into the thoracic/abdominal core body of the mammal and removed from the head of the mammal or cold is merely applied thereto. The subject methods and devices can also be used to reduce the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is removed from the thoracic/abdominal core body of the mammal and introduced into the head of the mammal or heat is merely applied thereto.

Abstract: A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.

Abstract: Aerobic exercise and strength training exercise are simultaneously provided to the body of a motionless patient or non-patient, to gradually increase body strength, increase elasticities of limb arteries, veins and adjacent muscles, reduce heart workload, increase whole body blood flow, provide more oxygen and nutrients to the whole body, increase the rate of removal of cell waste products, to treat, prevent, reduce the rate of progression and reduce the risk of recurrence of diseases and conditions of the whole body. Apparatus provides stretching and compressing muscle exercise for hips, shoulders and limbs of motionless patient or non-patient. A new scientific explanation of aerobic exercise, e.g. walking, is provided which shows the sequence of events within the body during aerobic exercise which causes whole-body benefits shown in hundreds of aerobic exercise studies. The explanation is applied to Alzheimer, Parkinson and Cancer studies to explain the results of the studies.

Abstract: A patient warming device includes a gasket coupled to an interior surface of a base film to define a target region that is attachable to a body surface of a patient. The base film extends from a perimeter of the gasket to provide a surgical drape. An evacuation port is in fluid communication with the target region. When attached to the patient, suction applied to the target region via the evacuation port vasodilates the body surface of the patient such that a heat source communicating with the target region increases a core temperature of the patient.

Abstract: Apparatuses, systems, and methods for applying reduced pressure to a tissue site on a foot are provided. An apparatus may include an insole and a tissue contacting surface covering at least a portion of the insole. At least one portion of the tissue contacting surface is removable to form a void. The apparatus may also include a reduced-pressure interface for receiving reduced pressure from a reduced-pressure source, and at least one flow channel fluidly coupled to the reduced-pressure interface and the void.

Abstract: A therapeutic glove of elastic synthetic fabric to which gold-coated self-expanding ring devices are affixed at selective locations adjacent the metacarpophalangeal (MCP) joints of the fingers of the hand without restricting movement of those joints. The affixing of rings on the interior of the glove along the MCP joints induces optimal gold abrasion therapy of joints that are afflicted by rheumatoid arthritis. The high purity gold-coating on the rings, combined with the snugness of the glove, increases the natural abrasion and absorption of the gold into the joint, which has the therapeutic effect of delaying joint erosion with daily wear.

Abstract: Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

Abstract: A female masturbation device includes a casing, a flexible cup body, a flexible piston, a slide bar, a silica-gel rod and a driver. An exterior wall of a lower end portion of the casing is connected with an upper end of the flexible cup body and an upper end of the flexible piston from the top down in turn. The flexible piston is provided within the flexible cup body forming a negative pressure region between the flexible piston and the flexible cup body. The slide bar passes through the flexible piston, an upper end of the slide bar is connected with the driver, and a lower end of the slide bar is tightly fastened with an upper end of the silica-gel rod. The flexible cup body has a through hole, an arched convergence part and an annular bottom ring. The female masturbation device has the obvious masturbation effect on female.

Abstract: The invention provides a treatment for congestive heart failure (CHF) in a patient. At least one pressure applicator is arranged externally around a body segment of the patient. Negative pressure, relative to atmospheric pressure, is applied to the body segment of the patient during cardiac systole using the pressure applicator, thereby reducing ventricular afterload in the patient. The negative pressure to the body segment of the patient is removed during cardiac diastole.

Abstract: A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s) of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing rims for surrounding each of the breasts and a regulated pump. The method for preparing the soft tissue site, and enhancing fat graft results, entails application of the distracting force to the targeted soft tissue site for several weeks prior to the graft procedure. A related aspect of the invention includes following the preparation steps by transfer of fat from other areas of the subject to the subject's breast(s), and then reapplication of the distractive force to the breast(s) that received the autologous fat graft. Alternatively, fat from genetically related sources may be used, and the fat may be further processed prior to injection.

Abstract: A method and device for treating wounds 10 of tissue 11 is disclosed. The method has the steps of applying a porous pad 12 upon the treatment surface of the tissue 11; covering the treatment surface and the porous pad 12 with a foil or sealing cover 14 for isolating the treatment surface and the porous pad 12 from the atmosphere; filling the volume under the foil or sealing cover 14 with fluid 100 and purging air from the volume under the foil or sealing cover 14 thereby fluid 100 saturating said porous pad 12: applying an acoustic shock wave treatment through the foil or sealing cover 14 or surrounding tissue 11 or a combination thereof sending acoustic shock waves 200 through the volume to the treatment surface and underlying tissue 11 and thereafter pulling a vacuum to create a sub-atmospheric pressure under the foil or sealing cover 14 wherein the combination of the applied acoustic shock waves 200 and sub-atmospheric conditions stimulates healing of the treatment surface and underlying tissue 11.

Abstract: A negative pressure, thermal energy device has an enclosure that receives a patient's body part. The body part is positioned in the enclosure and contacts a thermal energy contacting surface. The thermal energy contacting surface transfers its thermal energy to the body part. While in the enclosure, the body part is also exposed to a negative pressure to cause vasodilation. The combination of the vasodilation and the thermal energy transfer alter the patient's body core temperature. To ensure the body part remains in contact with the thermal contacting surface, the enclosure has a portion thereof that moves when negative pressure is in the enclosure. When the negative pressure is applied, the deforming enclosure material is pulled toward the body part to provide a positive pressure on the body part that ensures the body part effectively contacts the thermal energy contacting surface.

Abstract: The present invention relates to a method of delivering combined positive and negative pressure assist ventilation to a patient, wherein a positive pressure is applied to the patient's airways to inflate the patient's lungs, a negative pressure is applied around the patient's ribcage and/or abdomen in order to reduce a load imposed by the ribcage and/or abdomen on the patient's lungs, and application of the positive and negative pressures is synchronized.

Abstract: A device and a method for creating and/or maintaining an obstruction free upper respiratory passages. The device is configured to fit under the chin of a subject adjacent to the subject's neck at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The device is capable of exerting negative pressure on the surface of a subject's neck, displacing the soft tissue forward and enlarging the airway.

Abstract: Devices and methods for compressing a patient's limb or limbs (e.g., legs or arms) for treating or preventing ailments due to compromised venous or lymphatic circulation of the limb. Exemplary embodiments include, but are not limited to, sub-atmospheric compression, micro-pneumatic compression, and active fabric compression devices and methods.

Abstract: Devices that employ external compression stocking-type garments in the treatment of edema, chronic wounds, deep venous thrombosis prevention or claudication all share a number of significant limitations. These include the frequent need for custom fitting to assure an appropriate fit, vigilant maintenance to assure a continued “good fit,” limited compliance with proper use by patients and difficulty of application. There is a large body of evidence demonstrating that patients often decline to wear the compressive stockings as prescribed or in the form that would be most beneficial because they find these devices to be difficult to put on and take off. Building on the limitations of existing therapies, and distilled lessons learned from the field of prosthetics and wound healing, the present invention employs vacuum-assisted negative pressure to provide compression and help pump fluid from the tissues of affected limbs.