Abstract: The present invention is directed to the affixion of an exoskeleton device that can include multiple rotational degrees of freedom in its attachment mechanism to approximate linear motion orthogonal to the person's line of action. The present invention can include one or more additional, non-parallel degrees of freedom. The present invention provides a sliding mechanism for adjusting the exoskeleton mating point along the user's body.

Abstract: There is provided inter alia an injection pen system comprising an injector mechanism and a reservoir comprising an aqueous liquid pharmaceutical composition for delivery by means of said injector mechanism to a mammal wherein the composition comprises (i) an insulin compound, (ii) ionic zinc and (iii) an alkyl glycoside as a non-ionic surfactant.

Abstract: Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.

Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

Abstract: A flexible printed circuit flex-PCB sensor includes a sheet of electronically printable flexible material, sensor cells printed on said sheet and each including a sensitive element and a circuit. Each sensitive element is arranged to measure a predetermined physical parameter and to obtain an associated measurement signal. Each circuit is arranged to receive and process the measurements signal in order to obtain a corresponding output signal. Communication means are arranged to transmit the digital signals coming from said sensor cells to a remote processing circuit. The sheet is coiled according to a three-dimensional shape having a layered structure. Layers of said sheet are placed side by side and form a sensing border that is substantially perpendicular to the surface of said sheet. The relative position of each sensitive element and of each circuit inside the sensor relative to said sensing border depends on their relative position thereof.

Abstract: A surgical apparatus comprises a body, an ultrasonic transducer, a shaft, and an end effector. The ultrasonic transducer is operable to convert electrical power into ultrasonic vibrations. The body comprises a pivotal trigger. The shaft couples the end effector and the body together. The end effector comprises a clamp arm and an ultrasonic blade in acoustic communication with the ultrasonic transducer. The ultrasonic blade is operable to deliver ultrasonic vibrations to tissue. Pivotal movement of the trigger causes movement of the clamp arm. The trigger includes a compliant feature configured to limit the amount of force delivered to tissue by the clamp arm. The flexible feature may comprise a flexible band, living hinge, a series of living hinges, or a flexible tab.

Abstract: A method of delivery of an ultrasound-guided drug-loaded microbubble, an electronic device, and a computer-readable storage medium are provided. The method includes: emitting a first ultrasonic signal by utilizing an array transducer, to break a drug-loaded microbubble in a current breaking region; emitting a second ultrasonic signal by utilizing the array transducer, to obtain an ultrasound image; identifying a contour of a blood vessel of the breaking region based on the ultrasound image; and updating a characteristic parameter of the breaking region based on the contour of the blood vessel. According to the method, the breaking region is updated in real time based on the contour of the blood vessel, so that delivery accuracy of a drug-loaded microbubble is improved, and avoiding unnecessary tissue damage.

Abstract: An intraluminal ultrasound device includes a flexible elongate member configured to be inserted into a lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion, an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member, the ultrasound imaging assembly configured to obtain imaging data while positioned within the lumen of the patient; and a radiating member disposed at the distal portion of the flexible elongate member and in communication with an ultrasound transducer positioned outside of the patient, wherein the radiating member configured to transmit ultrasound energy from the ultrasound transducer within the lumen of the patient to apply an ultrasound therapy. Associated devices, systems and methods are also provided.

Abstract: An ultrasonic surgical instrument includes an end effector including an ultrasonic blade, an ultrasonic waveguide, an ultrasonic transducer assembly, and a carrier. The acoustic waveguide includes at least a proximal portion thereof extending along a longitudinal axis. The ultrasonic transducer assembly includes a fixation member and is operatively connected to the acoustic waveguide such that the acoustic waveguide is in acoustic communication with an ultrasonic transducer. The carrier has at least a portion thereof engaged with the fixation member of the ultrasonic transducer assembly thereby inhibiting movement of the ultrasonic transducer assembly relative to the carrier. The carrier movably supports the ultrasonic transducer assembly along the longitudinal axis such that the ultrasonic transducer assembly is configured to move from a proximal position on the longitudinal axis to a distal position on the longitudinal axis for inserting the ultrasonic blade into a patient.

Abstract: For the field of determining the position of an invasive device (1) a solution for improving the localization of the invasive device (1) is specified. This is achieved by an arrangement and a method for determining the position of an invasive device (1), wherein an optical shape sensing system for sensing a position and/or shape of the invasive device (1) is provided, wherein the system is arranged to localize at least one point Pi on the invasive device (1) at a position xi, yi, zi, with some error margin (2?xi, 2?yi, 2?zi) in a region of interest (3), localizing and reconstructing at least one point Pi on the invasive device (1) at a position xi, yi, zi, with some error margin (2?xi, 2?yi, 2?zi) in a region of interest (3) by the optical shape sensing system.

Abstract: A percussive massage device includes a housing. The housing defines a handle portion and a corner where the handle portion meets another portion of the housing. The percussive massage device also includes a motor contained within the housing, a reciprocation shaft coupled to the motor and configured to reciprocate when the motor is active, and a heart rate sensor located at the corner.

Abstract: The present disclosure is directed to an expandable energy delivery assembly adapted to deliver electrical energy to tissue. The assembly includes an elongate device and an expandable portion. The expandable portion includes an inflatable element, a single helical electrode disposed on the inflatable element, and at least one irrigation aperture within the inflatable element. The inflatable element is secured to the elongate device and the single helical electrode makes between about 0.5 and about 1.5 revolutions around the inflatable element. The at least one irrigation aperture is adapted to allow fluid to flow from within the inflatable element to outside the inflatable element.

Abstract: A surgical device. The surgical device may comprise a transducer, an end effector, a generator and a control circuit. The transducer may be configured to provide vibrations. The end effector may be coupled to the transducer and may extend from the transducer along the longitudinal axis. The generator may provide an electrical signal to the transducer. Also, the control circuit may modify a current amplitude of the electrical signal in response to a change in a vibration frequency of the end effector. Accordingly to various embodiments, the control circuit may detect a first contribution to a vibration frequency of the end effector, the first contribution originating from tissue in contact with the end effector. Also, according to various embodiments, the control circuit may indicate a change in a vibration frequency of the end effector.

Abstract: A surgical tool for a surgical robotic system, the surgical tool comprising: a surgical tool grasper having a jaw operable to perform a surgical procedure; a handle coupled to the surgical tool grasper and having a lever operable to actuate the jaw; and an actuation combiner mechanism coupled to the lever and operable to combine an actuation force output of the lever with an actuation force output of a motor to control the operation of the jaw or the lever.

Abstract: Disclosed is a surgical instrument having a housing, an end-effector, and a user interface. The end-effector includes a clamp arm and an ultrasonic blade configured to couple to an ultrasonic transducer and to a pole of an electrical generator. The clamp arm includes a clamp jaw pivotally movable about a pivot point, an electrode defining a surface configured to contact tissue and apply electrical energy to the tissue in contact therewith and configured to couple to an opposite pole of the electrical generator. The user interface includes a first activation button switch to activate a first energy source and a second button switch to select an energy mode for the activation button switch.

Abstract: The present application provides an ultrasonic wake-up system. The system includes an ultrasonic imaging device, an ultrasound stimulation device, and an ultrasound stimulation effect evaluation device, and acquires an ultrasonic image of a target object through the ultrasonic imaging device, transmits an ultrasound to the target object based on the ultrasonic image through the ultrasound stimulation device, and adjusts the transmitted ultrasound required through the ultrasound stimulation effect evaluation device. Therefore, peripheral nerves are accurately stimulated, an uplink reticular wake-up system is activated, so as to wake up patients with disorders of consciousness.

Abstract: Disclosed is a skin management device with an improved skin management effect as electric deep-heat by high frequency and heat by ultrasound physical vibration may be simultaneously provided to the skin.

Abstract: The tissue removal device using focused ultrasound includes a focused ultrasound output unit, a mode setting unit to set an output mode of the focused ultrasound, and a control unit to control output characteristics of the focused ultrasound according to the set mode, wherein the output mode is selected from a first mode for removing a tissue in a local area using a vapor bubble formed by the focused ultrasound, a second mode for removing a tissue in a narrower area than the first mode by controlling the output characteristics of the focused ultrasound immediately after the vapor bubble is formed by the focused ultrasound, and a third mode for obtaining a skin tightening effect by generating heating in a subcutaneous fat layer using focused ultrasound of lower intensity and a longer pulse length than the first mode and the second mode.

Abstract: Treatment device for ultrasonic treatment and high frequency treatment procedure is equipped with an ultrasonic transducer including piezoelectric elements converting electrical power into ultrasonic vibrations. The treatment device includes a transmission rod with a treatment probe and jaw for clasping objects. The transmission rod includes one or more features for damping, to minimize or prevent excess vibrations and to, among other things, decrease frictional heat caused by the friction between the damping features and the transmission rod arising from attenuating the ultrasonic vibrations.

Abstract: Some embodiments provide a method including applying high-intensity focused ultrasound energy to a skin treatment area with simultaneous movement of the transducer body across the skin treatment area to form a pattern of treatment lines in tissue at a first depth below the surface of the skin. For example, the pattern of treatment lines may be formed by the movement of the transducer body during one or more treatment cycles. A preferred pattern of treatment lines includes treatment lines that intersect. Furthermore, the method may further include applying the high-intensity focused ultrasound energy to the skin treatment area with simultaneous movement of the transducer body across the skin treatment area to form a second pattern of treatment lines in tissue at a second depth below the surface of the skin and a third pattern of treatment lines in tissue at a third depth below the surface of the skin.

Abstract: A cosmetic device includes: a body from which a first head portion and a second head portion protrude in directions different from each other; a front assembly disposed on the first head portion; a rear assembly disposed on the second head portion; and an iontophoresis electrode disposed to be spaced apart from the front assembly and the rear assembly on an outer surface of the body. The front assembly includes an inner electrode, an outer electrode disposed outside the inner electrode, and an ultrasonic vibrator disposed on a rear surface of the inner electrode to generate ultrasonic waves. The rear assembly includes a thermoelectric element and a cooling cover cooled by the thermoelectric element.

Abstract: A surgical instrument includes a shaft, an ultrasonic transducer, a waveguide acoustically coupled with the ultrasonic transducer and extending distally through the shaft, and an end effector arranged at a distal end of the shaft. The end effector includes an ultrasonic blade acoustically coupled with the waveguide, a clamp arm movable relative to the ultrasonic blade for clamping tissue, and an RF electrode operable to seal tissue with RF energy. The ultrasonic transducer is operable to drive the waveguide and the ultrasonic blade with ultrasonic energy. The surgical instrument further includes an ultrasonic electrical circuit operable to energize the ultrasonic transducer, and an RF electrical circuit operable to deliver RF energy to the RF electrode. A return path of the ultrasonic electrical circuit and a return path of the RF electrical circuit pass through a shared electrically conductive element.

Abstract: A method for analyzing a digestive tract of a patient using ultrasound. The method includes receiving a plurality of ultrasound images taken over a time series, determining movement characteristics of objects within the ultrasound images based on movement of one or more pixels in the ultrasound images over the time series, and outputting a visual data that describes the movement characteristics.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of lymphatic tissue that include applying one or more energy pulses to a neuron of a subject, e.g., via an electrode positioned to deliver sufficient energy to the neuron, to modulate immune function. For example, an adaptive immune reflex of a subject may be modulated via neuromodulation.

Abstract: A transducer transmits into the bone a first plurality of excitation pulses at a plurality of frequencies and measures a plurality of echoes corresponding to the plurality of excitation pulses. An ultrasound machine calculates a plurality of energies each corresponding to a respective one of the plurality of echoes and identifies a lowest echo corresponding to a lowest of the plurality of energies. The ultrasound machine matches the lowest echo to a corresponding one of the first plurality of excitation pulses, the corresponding one of the first plurality of excitation pulses having a chosen frequency. The ultrasound machine generates an acoustic impulse response by deconvolving the corresponding one of the first plurality of excitation pulses with the lowest echo, and generates an updated sensing matrix by convolving the initial sensing matrix with the acoustic impulse response. Subsequent ultrasounds use the updated sensing matrix.

Abstract: Methods of using pulsed focused ultrasound (pFUS) therapy to treat pancreatic disorders such as type 1 diabetes, pancreatitis, and pancreatic cancer are provided. The methods utilize pulsed focused ultrasound (pFUS) therapy either by itself or in combination with islet transplantation and/or stem cell therapy to promote regeneration of damaged pancreatic tissue, increase insulin secretion in response to glucose, or improve engraftment and revascularization of transplanted islets or beta cells. Additionally, methods of using pFUS are provided for modulating paracrine secretion in the pancreas, islets, beta cells, or stem cells, or at a transplantation site to therapeutically alter levels of various factors including, without limitation, cytokines, growth factors, angiogenic factors, and cell adhesion molecules.

Abstract: A vibration transmission member for an ultrasonic treatment tool includes: a main body including a central axis, a distal end (DE), and a proximal end (PE), a center moving portion (CMP) at a distal side of a node where the DE meets the CMP, the node being at a most DE of the main body, and a curved portion (CP) at a distal side of the CMP. In a direction from a PE of the CP toward a DE of the CP, the CP is curved in a first direction. The center of gravity of the CMP moves along the CMP toward the DE of the CMP, the center of gravity moves relative to the central axis in a second direction. The CP extends from the DE of the main body to the PE of the CP. The CP includes a plurality of notches along a periphery of the CP.

Abstract: A surgical handpiece and an autoclavable surgical handpiece are disclosed. The surgical handpiece and the autoclavable surgical handpiece include a housing and a visible light emitter disposed within the housing. The surgical handpiece includes a cable adjacent to the housing and a strain relief member coupled to the cable, the strain relief member being disposed adjacent to the housing and configured to transmit visible light emitted by the visible light emitter therethrough. The autoclavable surgical handpiece includes a potting material disposed between the visible light emitter and the housing, the potting material having a melting point above 120 degrees Celsius and being configured to thermally insulate the visible light emitter and to transmit visible light emitted by the visible light emitter therethrough.

Abstract: The present embodiment comprises: an ultrasonic transducer for generating ultrasonic waves; an inner electrode having a space in which the ultrasonic transducer is accommodated; a window disposed outside the outer periphery of the inner electrode; an LED PCB disposed at the rear of the window and having an LED disposed thereon; and an outer electrode spaced apart from the inner electrode on the window, wherein the inner electrode comprises: a front body having the ultrasonic transducer disposed on the rear surface thereof; and a hollow body protruding backward from the outer periphery of the front body and having a space formed therein, wherein an inner waterproofing ring is disposed between the hollow body and the window.

Abstract: A medical system includes an outer catheter comprising one or more first lumens, a sealing device coupled to the outer catheter, an inner instrument configured to be slideably deployed through one of the one or more first lumens and comprising one or more first sensors configured to detect one or more anatomical features below a surface of the anatomic passageway, one or more second sensors, and a processor. The processor is configured to detect bleeding into the anatomic passageway from outside the anatomic passageway using the one or more second sensors and disable advancement of the inner instrument when the one or more first sensors detect the one or more anatomical features. The one or more second sensors are configured to be positioned distal to the sealing device and mounted on the inner instrument near a distal end of the inner instrument.

Abstract: A tool for creating an incision at a surgical site includes a body for use with a robotic end effector having a proximal end and a distal end, and a blade positioned at the distal end of the body, the blade having a proximal end and a distal end, the blade having a cutting edge defining a first portion extending outwardly from or adjacent to the proximal end to a maximum width and a second portion extending inwardly from the maximum width to a sharp distal tip.

Abstract: An adapter assembly is configured to provide a fluid flow path for a rotary tool having a punch. The adapter assembly has a housing removably coupled to the rotary tool. the rotary tool has a lower end near a tip and an upper end away from the tip. A gasket is detachably arranged within the housing, around the punch and further comprising an upper seal portion and a lower seal portion. The upper seal portion has a smaller inner diameter than the lower seal portion. A fluid path is arranged through the housing, at least one hole in the gasket, and out of a lumen in the punch.

Abstract: A flue for use with an ultrasonic surgical tip, comprising protrusions or bumps on its inner surface with improved protrusion pattern, density and location. The flue has enhanced cooling effect for the ultrasonic surgical tip.

Abstract: Described herein are accelerator devices for providing a couplant while moving an ultrasound probe over a surface. The devices may include a reservoir configured to hold ultrasound couplant. The reservoir may attach to a probe so as to dispense the couplant at one or more locations along a perimeter of the probe while moving the ultrasound probe over the surface. The devices may additionally, or alternatively, include a membrane configured to hold ultrasound couplant. The membrane may charge a couplant layer of an ultrashield prior to or while moving the ultrasound probe over a surface during an ultrasound procedure.

Abstract: Systems and methods for performing spine surgery. A retractor may be positioned within a patient to facilitate maintaining a volume of fluid at the surgical site. The retractor includes an opening capable of receiving one or more surgical instruments, for example, a cutting instrument and an endoscope. A cutting member of the cutting instrument is submerged and operated within the volume of fluid to resect tissue, for example, within the intervertebral disc space. The volume of fluid is maintained at the surgical site improves cooling of the surgical site and visualization of the surgical site via the endoscope during resection. The volume of fluid is maintained at the surgical site via the surgical system. The surgical system may include a sensor for measuring the level of fluid in the retractor, an inflow source and an outflow source in fluid communication with the retractor, and a controller controlling the surgical system.

Abstract: Systems and methods can include wearable, non-invasive ultrasound modalities for treating a variety of medical conditions, including but not limited to peripheral vascular disease. The modality could be therapeutic ultrasound (TUS), and be configured to promote angiogenesis within a patient via stimulation of cavitation and shear stress, among other mechanisms.

Abstract: A method for covertly creating adverse health effects in a human subject includes generating at least one electromagnetic wave at a frequency within the range of about 300 MHz (megahertz) and about 300 GHz (gigahertz). The at least one electromagnetic energy wave is pulsed at a pulse frequency within a target range of human neural oscillations. The at least one pulsed electromagnetic wave is remotely transmitted to the subject's brain.

Abstract: The invention relates to a position determining device for determining a position of an elongate object within a tubular structure, said position determining device comprising a first providing unit for providing a first distribution of curvature values at a plurality of first points along a path within the tubular structure. The position determining device further comprises a second providing unit for providing a second distribution of strain values or of curvature values at a plurality of points along the object, and a position determining unit for determining the position of the object relative to the path on the basis of the first and second distributions.

Abstract: A method for minimally invasive laser ablation of a target tissue within a patient while sparing tissue within a safety zone proximate to the target tissue, comprising: guiding a laser fiber within a patient with a guidance tool; measuring a temperature within the target tissue and the safety zone based on an invasive and a non-invasive thermal sensor; computing a thermal profile in conjunction with a real-time tissue image adapted for guidance of the laser fiber with the guidance tool within the patient; and controlling a laser to deliver energy through the laser fiber, to deliver a minimally therapeutic ablation therapy to the target tissue while ensuring that the safety zone is maintained in a non-ablation condition, based on at least a treatment plan, the measured temperature, and the thermal profile.

Abstract: A device and method for perforating a dense bone layer. The device includes a vibration generator for generating mechanical vibration, in particular ultrasonic vibration, and an instrument with an elongated shaft and a distal end piece including a perforator. The distal end piece is arranged at a distal end of the shaft and the proximal end of the shaft is connected or connectable to the vibration generator. The perforator has the form of a solid or a hollow cylinder. The vibration generator, the shaft and the distal end piece are adapted to each other for the shaft to transmit, when connected to the activated vibration generator, mechanical vibration from the vibration generator to the distal end piece and for vibrating the perforator in a direction parallel to its cylinder axis.

Abstract: A method for treating a kidney with focused extracorporeal shockwaves in a noninvasive manner. The method configured for the treatment of chronic kidney disease (CKD) at any one of CKD stage 1 to CKD stage 4. The method of treatment comprising using non-invasive extracorporeal shockwaves having an energy density of 0.02 to 0.18 mJ/mm2 that are delivered to at least one treatment zone selected from various focal zones encompassing renal structures.

Abstract: Ultrasonic transducers may be used to track the position of an object. For example, eyewear such as a pair of glasses or other head-mounted device may use ultrasonic transducers to track a user's eye position and gaze direction. To increase positioning accuracy over short-range distances, an array of ultrasonic transducers with different center frequencies may be formed on a common substrate. The closely spaced ultrasonic transducers with relatively small individual bandwidths may be used to simulate a single transducer with a larger bandwidth. Control circuitry may adjust the phases of the transducers in the array to steer the ultrasonic signal beam towards the user's eye and/or to receive an ultrasonic signal beam from the direction of the user's eye. The control circuitry may use time delay and/or phase delay measurement techniques to determine a distance and/or direction to the user's eye using the ultrasonic transducer arrays.

Abstract: A system and method for controlling the delivery of ultrasound energy to a subject is provided. In particular, such a system and method are capable of safely disrupting the blood-brain barrier. Ultrasound energy is delivered to produce cavitation of an ultrasound contrast agent at a selected pressure value. An acoustic signal is acquired following cavitation, from which a signal spectrum is produced. The signal spectrum is analyzed for the presence of harmonics, such as subharmonics or ultraharmonics. When subharmonics or ultraharmonics are present, the pressure value is decreased for subsequent sonications. If a previous sonication resulted in no subharmonics or ultraharmonics being generated, then the pressure value may be increased. In this manner, the blood-brain barrier can be advantageously disrupted while mitigating potentially injurious effects of the sonication.

Abstract: Among the various aspects of the present disclosure is the provision of a noninvasive and localized brain liquid biopsy using focused ultrasound. Briefly, therefore, the present disclosure is directed to methods and systems to identify brain lesion or tumor characteristics without the need for a solid brain biopsy.

Abstract: An ultrasound therapy device for generating ultrasound therapy. The ultrasound therapy device includes a wearable structure, ultrasound transducer units, a tightening mechanism, a memory, and a processor. The wearable structure is securable to a user to transmit the ultrasound to a target therapy area of a user including at least one of a kidney region, a lung region, and a lower limb of the user. The ultrasound transducer units are attachable and repositionable in the wearable structure to generate and deliver the ultrasound to the target region. The ultrasound transducer units are arranged in an array. The array of ultrasound transducer units is mechanically moved within the wearable structure and is in contact with a material to facilitate penetration of ultrasound into the user's body.

Abstract: A device for providing oral care includes at least one lumen fluidly coupled to a brush head. The lumen is adapted to suction fluid via an aperture disposed within the brush head. The brush head may be provided an oral cleaning fluid to facilitate cleaning of oral anatomy. The oral cleaning fluid may be provided within a cup provided within a containment assembly coupled to the oral care tool. Alternatively, or in addition, the cleaning fluid may be provided via fluid reservoir fluidly coupled to the oral care tool. The brush head comprises a bristles section and a foam section.

Abstract: Systems for promoting sexual well-being in males and for treating erectile dysfunction using acoustic energy.

Abstract: Various embodiments are generally directed to a flexible elongate member (e.g., endoscopic accessory tool) positionable into and/or through selected anatomies, such as by generating images to position components of a flexible elongate member or to localize anatomic features, for instance. Some embodiments are directed to generating images with a plurality of imaging techniques to localize anatomic features and/or components of a flexible elongate member for one or more of inspection, orientation, and/or facilitating access to body passageways or lumens.

Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

Abstract: Embodiments of a dermatological cosmetic treatment and imaging system and method can include use of transducer to simultaneously or substantially simultaneously produce multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, the cosmetic treatment system may be used in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided.