Abstract: A high-frequency operation apparatus includes a grasping portion for grasping a treatment target living tissue, an electrode for supplying a high-frequency current to the living tissue, a high-frequency current supplying section that generates the high-frequency current necessary for treatment, a cable section that transmits the high-frequency current, an impedance measuring section for measuring an impedance value of the living tissue, a detecting section that detects that the impedance value reaches an impedance threshold at a time when moisture in the living tissue starts to evaporate, a measuring section that measures an output time of the high-frequency current after the detection, a storing section that stores a set time, and an output control section that performs control for stopping an output when the output time of the high-frequency current reaches the stored set time.

Abstract: A method of delivering a substance includes providing a substance at a location in a gastrointestinal (GI) tract, excluding a buccal membrane, of a biological body; and applying ultrasonic waves, having a frequency between about 20 kHz and about 10 MHz, at the location. The method can include storing the substance in at least one reservoir and exposing a medium within or of the GI tract to the substance. The method can further include delivering a device into the GI tract, the device including at least one ultrasound transducer and circuitry; powering the at least one ultrasound transducer and circuitry from within the device; and driving the at least one ultrasound transducer, using the circuitry, in a manner causing the at least one ultrasound transducer to emit ultrasonic waves to a medium within or of the GI tract.

Abstract: An apparatus for interfacing between tissues being stimulated is provided. The apparatus includes an electric source capable of generating an applied electric field across a region of tissue and/or a means for altering at least one electromagnetic characteristic of the region of tissue relative to the applied electric field and an interface component, such interface component creating an interface between the region of tissue and the applied electric field or the means for altering at least one electromagnetic characteristic of the region of tissue.

Abstract: A system and method for treating tissue uses an ultrasound therapy system including an ultrasonic applicator having has at least one transducer element. Steering and focusing of ultrasound beams uses at least one variable focus lens, which may be a fluid focus lens, attached to each transducer element so that focus of the variable focus lens is controlled by a voltage signal. A treatment controller receives input from an imager and controls the voltage applied to the variable focus lens. The treatment controller controls the lens voltage signals, at least partially determined by the input from the imager, and directs an ultrasonic treatment beam emitted by the transducer element. Fine adjustment of the therapy beam is achieved to deliver therapy for various prostate sizes and shapes while avoiding damage to critical structures such as the rectal wall and nerve bundles.

Abstract: A biomedical device (1) for robotized rehabilitation of a human upper limb, particularly for neuromotor rehabilitation of the shoulder and elbow joint, includes a first rigid rod (2) and a second rigid rod (3), both of which can be associated with the upper limb (4) of a patient (5) and are articulated to each other at two adjacent ends (2a, 3a) thereof by way of a first universal joint (6) which can be arranged proximate to the elbow joint (7) of the upper limb (4).

Abstract: A manufacturing method of an ultrasonic probe includes analyzing a first lateral vibration which is superposed on a longitudinal vibration because of an asymmetric shape of a distal asymmetric portion when the ultrasonic probe is longitudinally vibrated. The manufacturing method includes specifying a bending position to bend a proximal-direction side part of the ultrasonic probe so that the proximal-direction side part is parallel to a X-Y plane and tilted relative to a X-axis, a second lateral vibration, which has the same wavelength and vibration direction as the first lateral vibration and which is in anti-phase with respect to the first lateral vibration, being superposed on the longitudinal vibration and the first lateral vibration in the ultrasonic probe while the ultrasonic probe is bent at the bending position.

Abstract: A method for pressure-assisted irreversible electroporation of tissue cells, including placing one or more electrodes near tissue cells to be treated, positioning a pressure source operable to apply pressure pulses to the tissue cells, and applying to the tissue cells a combination of electrical pulses through the one or more electrodes and pressure pulses from the pressure source such that the combination is sufficient to induce irreversible electroporation of the tissue cells, and wherein the electrical pulses without the pressure pulses are insufficient to induce irreversible electroporation of the tissue cells.

Abstract: A treatment apparatus for external application to a mammal body, comprising a housing, a transducer element, adapted to provide an output towards and/or into the mammal body, a switch element, adapted to activate the transducer element in accordance with a first predetermined condition and deactivate the transducer element in accordance with a second predetermined condition, a feedback element, adapted to provide at least one first feedback signal in response at least a third predetermined condition, and a resilient coupling element, adapted to operatively couple the transducer element to said housing.

Abstract: A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive laparoscopic or hysteroscopic procedures, is used to effectively treat fibroids within the myometrium in lieu of major surgery. The applicators are configured with high-power capabilities and thermal penetration to treat large volumes of fibroid tissue (>70 cm3) in short treatment times (3-20 minutes), while maintaining three-dimensional control of energy delivery to thermally destroy the target volume.

Abstract: A method for disrupting or destroying selected pathogens located within the body of an organism the method including the non-invasive administration to pre-selected locations on or in the organism of an amount of low intensity ultrasonic energy, effective to disrupt or destroy the selected pathogens but not deleteriously affect the organism, the low intensity ultrasonic energy falling within predefined ranges of frequencies, wherein the predefined range of frequencies is one or more ranges of frequencies at which the low intensity ultrasonic energy has optimal effectiveness in disrupting or destroying a particular pathogen, and the intensity of the low intensity ultrasonic energy falling within predefined ranges of intensity, wherein the predefined range of intensity of low intensity ultrasonic energy is such as to allow for disruption or destruction of the selected pathogens but not deleteriously affect tissue of the organism surrounding the selected pathogens.

Abstract: The present disclosure relates to an electronic therapy device including automatic controlled application of energies along with feedback control using sensors for improved synergistic effects and further the device is configured to be used for longer periods of time for improved and optimal therapeutic results without causing any adverse effects, the device can be used for pain management, healing, fitness, cosmetic and topical delivery related applications and a method for performing electronic therapy using the said portable electronic device.

Abstract: Various methods and devices for minimally invasive treatment and prevention of conditions of the fascia are provided. In one aspect, a method includes providing an acoustic wave source effective to deliver a focused acoustic wave to a target site within a patient's body, and focusing an acoustic wave through a patient's skin such that at least one location in the patient's fascia is fenestrated in a desired pattern.

Abstract: A combination device for applying a treatment of light and ultrasound on a tattooed area of a patient desiring tattoo removal. The device includes an ultrasound and a LED light source. The ultrasound source produces high-frequency ultrasound waves. These waves are applied directly to the tattooed area for a first specified period of time resulting in release of tattoo ink from tattooed cells. The LED source produces a continuous high-intensity light that is applied directly over the entire tattooed area for a second specified period of time resulting in degradation of the tattoo ink.

Abstract: Disclosed are methods and systems for non-invasive neuromodulation using ultrasound for cognitive enhancement. Cognitive enhancement can be used for mitigation of abnormal conditions such as Alzheimer's Disease, Parkinson's Disease or stroke, or for enhancement in a normal individual. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, mechanical perturbation, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.

Abstract: A method for acoustic tomography within a patient may include generating a focused ultrasonic signal using a transducer is provided; the ultrasonic signal forming a path within the patient. The method includes directing the ultrasonic signal on a spot within the patient; scanning the spot in a predetermined pattern about a volume within the patient; receiving an ultrasonic echo in the transducer; converting the ultrasonic echo into a voltage; selecting a frequency band from the voltage; amplifying the voltage in the selected frequency band with a processing circuit; and generating an image of the volume within the patient structure utilizing the amplified voltage. A method for recanalization of a blood vessel including the above acoustic tomography steps is also provided.

Abstract: A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve.

Abstract: A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve.

Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

Abstract: A treatment portion includes a treatment region which treats a treatment part with a liquid which has flowed out from a distal end opening portion and with ultrasonic vibrations while the treatment region is in abutment with the treatment part. The treatment portion further includes a hydrophilic region which is formed by the application of a hydrophilic coat and which is provided in part of the circumferential surface of the treatment portion to be provided from the treatment region to an end portion of the treatment portion located in the distal end opening portion in a longitudinal axis direction.

Abstract: A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.

Abstract: A method and apparatus for applying neuromuscular electrical stimulation to an agonist/antagonist muscle pair to move a limb about a joint includes generating a first pattern of neuromuscular electrical stimulation pulses for output through a first channel to a first pair of electrodes and generating a second pattern of neuromuscular stimulation pulses for output through a second channel to a second pair of electrodes. The first pair of electrodes are attached to the agonist muscle of the agonist/antagonist muscle pair, and the second pair of electrodes are attached to the antagonist muscle. A first pattern of electrical stimulation pulses is transmitted through the first pair of electrodes to the agonist muscle at a first intensity level to initiate contraction of the agonist muscle, and then at a second intensity level which is less than the first intensity level to continue contraction of the agonist muscle.

Abstract: An ultrasonic probe includes a first coupled vibration member and a second coupled vibration member each of which extends along a longitudinal axis between a first anti-node position of an ultrasonic vibration and a second anti-node position of the ultrasonic vibration located to a distal direction side of the first anti-node position. The second coupled vibration member vibrates in the same mode as the first coupled vibration member. A first groove of the first coupled vibration member and a second groove of the second coupled vibration member cooperate with each other and thereby form at least a part of a passage inside a multiple-members vibrating portion formed by the first coupled vibration member and the second coupled vibration member.

Abstract: An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.

Abstract: Methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.

Abstract: An ultrasonic surgical clamp coagulator apparatus is configured to effect cutting, coagulation, and clamping of tissue by cooperation of a clamping mechanism of the apparatus with an associated ultrasonic end-effector. The handle of the apparatus is configured to permit hand activation for cutting, coagulation, and clamping of tissue during surgical procedures. In order to promote convenient and efficient use of the apparatus, one or more fingertip controls are provided directly into the disposal shears handle in a position that allows surgeons to activate the device without repositioning their hand. The one or more buttons provide independent control of the power levels available from the generator, matching the two foot pedal configuration of the prior art.

Abstract: Improved devices, systems, and methods treatment of patients can be used to help mitigate injury to the kidneys by applying cyclical mechanical pressure energy at low intensities. The energy often be selectively directed from non-invasive transducers disposed outside the patients. The energy will typically comprise low frequency ultrasound energy, shock wave energy, or the like, and may induce the generation and/or release of nitric oxide, thereby enhancing perfusion and ameliorating tissue damage. Superimposed micro and macro duty cycles may help avoid thermal and other injury to tissues of the patient during treatment. Bilateral treatments are facilitated by a support structure that orients at least one transducer toward each kidney.

Abstract: Methods for determining the shear modulus of a tissue of an individual are disclosed. In one embodiment, an acoustic pulse is transmitted and a reference echo signal is received. A first push pulse is transmitted at a second location of the individual. A second push pulse is transmitted at a third location of the individual. A series of tracking pulses are transmitted at the first location and a tracking echo signal is received from each tracking pulse. The effect of the first and second push pulses on the tissue is determined through analysis of the tracking echo signals. The shear modulus of the tissue is calculated based on the effect of the push pulses on the tissue. A system for imaging a region of tissue is presented.

Abstract: A method and system including an applicator for treating dermatological conditions such as warts is presented for applying ultrasonic energy from a specially-designed ultrasonic energy applicator designed for use with localized dermatological conditions to heat an affected localized region sufficiently to achieve a desired therapeutic result. Specific embodiments include temperature measurement and/or sensing and/or actuation by way of a temperature sensor coupled to the ultrasonic energy applicator. Also, a medicated ultrasound-compatible patch is disclosed for applying to a region of tissue to be treated and includes substances known to aid in the treatment of a condition and adapted for transmitting the ultrasound energy into the region of tissue.

Abstract: A switched resonant power amplifier system for ultrasonic transducers is disclosed. The system includes an amplifier that receives and processes a driver output signal for generating a drive signal that is provided to an ultrasonic device for controlling output of the ultrasonic device. An output control circuit receives and processes a signal related to a feedback signal generated by the ultrasonic device and a divider reference signal, and generates a compensated clock signal that is adjusted for at least one of phase and frequency differences between the received feedback signal and the divider reference signal. A compensated drive circuit receives and processes the compensated clock signal for generating the divider reference signal, and for generating the driver output signal.

Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with ultrasound are disclosed. In an aspect, neural activity is blocked cyclically with an ultrasonic blocking stimulus source positioned adjacent a skin surface in a vicinity of a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.

Abstract: Methods and apparatuses are provided for initiating stroke treatment “in the field” and/or during the transport of the patient to a care facility. The capability is provided to adjust automatically to the individual “therapeutic window” for each single patient, which is crucial because of the significant differences in skull morphology between humans of different age, gender and race. Further, the methods and apparatuses are based on the use of non-invasive application of ultrasound, as well as the non-invasive application of ultrasound in combination with an acoustically active agent, such as microbubbles, where stable cavitation of the microbubbles caused by the ultrasound may be relied upon as an underlying mechanism for both the therapeutic application as well as its control.

Abstract: An ultrasonic irradiation device 10 includes: an ultrasonic irradiation pad 110 including at least two output elements for emitting supersonic waves with output strength in a range of 50±5 mW/cm2 to 110±5 mW/cm2 at output frequency in a range of 500±50 kHz to 800±50 kHz; drive control device 11 that drivingly controls the ultrasonic irradiation pad 110; and fastening device 120 that fastens the ultrasonic irradiation pad 110 in a state of being in close contact with a forearm 50 of the living body, in which the fastening device 120 is formed into a deformable strip having a removable fixed portion 120a in an end portion.

Abstract: A treatment apparatus includes an ultrasonic vibration source, an ultrasonic treatment portion which is configured to treat living tissue by ultrasonic vibration transmitted from the ultrasonic vibration source, and a micrograin feeder which is configured to supply liquid containing micrograins to between the ultrasonic treatment portion and the living tissue. Whole micrograins within the micrograin-containing solution has a grain size equal to or smaller than an amplitude of the ultrasonic vibration.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.

Abstract: Systems and methods for laxative-free colonoscopy include an ultrasound transducer housing positioned at or near the operable end of the flexible tube, the housing including an ultrasound transducer to generate ultrasound energy. The flexible tube with ultrasound transducer is inserted into a gastrointestinal tract. A water flow channel delivers water to the gastrointestinal tract. The ultrasound energy and water liquefy stool in the gastrointestinal tract, and the liquefied stool is removed from the gastrointestinal tract.

Abstract: The present invention relates to a new non-invasive method for inducing angiogenesis and more particularly coronary angiogenesis wherein an operator applies localized percussion upon the upper torso proximate an ischemic myocardial region, whereby the percussive forces penetrate to cause sheer stresses to the endothelium of the coronaries which lie thereupon, and thereby cause new coronary growth by virtue of endogenous liberation of beneficial angiogenic mediators. A pair of vibratory contacts are advantageously applied to rib-spaces to either side of the sternum (or alternatively to the upper back), where-after percussion is applied at the resonance frequency of the heart/epimyocardium at a displacement amplitude of 0.1 mm-15 mm (preferably greater than 1 mm), such as to maximize an internal oscillatory effect. The system is also adaptable for cerebral and peripheral vasculature applications. Ultrasonic imaging may optionally be utilized to direct percussive therapy.

Abstract: A treatment is described for delivering oxygen to tissue, especially hypoxic tissue. A medium saturated with gas is delivered to the tissue. Dissolved gas is transferred from the medium to the tissue. Ultrasound is transmitted to the tissue to enhance the transfer of gas to the tissue.

Abstract: A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method includes: advancing an ultrasound catheter to or in proximity to the subject's treatment site; infusing microbubbles into or proximal to the treatment site; and delivering ultrasonic energy from the ultrasound catheter. The ultrasonic energy may be adapted for: imaging the treatment site, translating the microbubbles into or in the vicinity of the treatment site and/or rupturing the microbubbles.

Abstract: An apparatus and a method for treating adipose tissue located beneath a patient's skin is disclosed herein. In some embodiments, the apparatus includes a sonotrode 140 and an ultrasound transducer 130 operative to induce longitudinal and/or transversal ultrasound vibrations in a least a portion of the sonotrode 140. In some embodiments, the apparatus provides a “cold” or “transverse” mode where ultrasound energy delivered to the patient is primarily energy of transverse ultrasound waves, and a “hot” or “longitudinal” mode where ultrasound energy delivered to the patient is primarily energy of longitudinal ultrasound waves. The longitudinal waves may be useful for ‘pre-heating’ tissue of the patient before delivering the transverse waves.

Abstract: Stem cells are proliferated with the application of acoustic pressure waves, including cambium cells of periosteum treated in-vivo with acoustic pressure waves. Following harvesting and viability assessment of in-vivo or in-vitro proliferated stem cells, acoustic pressure waves are applied to enhance in-vivo or in-vitro differentiation either before or after implantation of the stems cells to an organism. Acoustic pressure waves also stimulate an implantation site to enhance viability and to grow desired tissue.

Abstract: Provided is an ultrasonic vibration device with which it is possible to efficiently remove fat by generating vibrations not only in the direction parallel to a probe but also in the direction orthogonal to the probe. Provided is an ultrasonic vibration device including a polygonal columnar elastic body formed of an elastic body; a piezoelectric element that is secured to a side surface of the polygonal columnar elastic body and that is polarized in a plate-thickness direction thereof; a rod-like contactor that is secured to an end portion of the polygonal columnar elastic body and that has a smaller diameter than the polygonal columnar elastic body; and a drive-pulse generating circuit that generates a bending vibration in the polygonal columnar elastic body by applying an AC voltage in the plate-thickness direction of the piezoelectric element, thus generating an ultrasonic vibration in the rod-like contactor.

Abstract: Disclosed are methods for treating a volume of material by concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field. Also disclosed are devices suitable for concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field into the same volume of material. In some embodiments, the disclosed methods and devices are implemented for the treatment of subcutaneous fat.

Abstract: Described herein are methods and devices for selectively applying either fluids (e.g., anesthetics, nerve-blockers, etc.) or energy, such as radiofrequency or ultrasound energy, to a target tissue from within a blood vessel while minimizing the amount of fluid or energy applied to non-target tissue. The catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter. In addition, catheters can include energy applying features for delivering energy to the target tissue.

Abstract: A method of treating a condition associate with accumulation of an agent in cells in a patient includes exposing the cells to ultrasound, to selectively kill or induce apoptosis in the cells. The cells include the accumulated agent.

Abstract: A therapeutic apparatus comprising a high intensity focused ultrasound system (302) for sonicating a sonication volume (324) of a subject (320). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (350) within an imaging volume (316). The sonication volume is within the imaging volume. The therapeutic apparatus further comprises a controller (304) for controlling the therapeutic apparatus. The treatment plan comprises instructions for controlling the operation of the high intensity focused ultrasound system. The controller is adapted for sonicating (100) the target volume using the high intensity focused ultrasound system. The controller is adapted for repeatedly acquiring (102) magnetic resonance thermometry data using the magnetic resonance imaging system during execution of the treatment plan.

Abstract: A medical device for removing pathogens from a patient is disclosed. The medical device comprises a signal generator that produces a sound wave transmitted from a single electrode into the body of the patient. The single electrode disc can be disposed on the surface of an ergonomically designed housing that can be held by the patient in one hand or otherwise rest against the surface of the body of the patient hands-free.

Abstract: A method and system uniquely capable of generating thermal bubbles for improved ultrasound imaging and therapy. Several embodiments of the method and system contemplates the use of unfocused, focused, or defocused acoustic energy at variable spatial and/or temporal energy settings, in the range of about 1 kHz-100 MHz, and at variable tissue depths. The unique ability to customize acoustic energy output and target a particular region of interest makes possible highly accurate and precise thermal bubble formation. In an embodiment, the energy is acoustic energy. In other embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents (including monopolar and bipolar radio-frequency current). In an embodiment, the energy is various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling.

Abstract: An apparatus for interfacing between tissues being stimulated is provided. The apparatus includes an electric source capable of generating an applied electric field across a region of tissue and/or a means for altering at least one electromagnetic characteristic of the region of tissue relative to the applied electric field and an interface component, such interface component creating an interface between the region of tissue and the applied electric field or the means for altering at least one electromagnetic characteristic of the region of tissue.

Abstract: In some embodiments, sympathetic nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some embodiments, different types of energy sources are utilized singly or combined with one another. In some embodiments, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents.

Abstract: A system for providing non-invasive ultrasound based treatment to a region of interest is provided. The system comprises an imaging unit for imaging one or more tissue types in the region of interest, an image processing unit that is configured to identify the one or more tissue types in the region of interest, an ultrasound transducer that is configured to focus an ultrasound beam to ablate at least a portion of the identified tissues, and a controller unit that controls a delivery of the ultrasound beam to the region of interest.