Abstract: Provided according to some embodiments of the invention are wound dressings that include a polymer matrix and nitric oxide-releasing polysiloxane macromolecules within and/or on the polymer matrix. Also provided are wound dressing kits and methods of using and forming such wound dressings.

Abstract: Embodiments of the invention include silica fiber compositions useful for treatment of animal wounds and tissue, as well as for other applications in industry. The fiber compositions may be formed via electrospinning of a sol gel produced with a silicon alkoxide reagent, such as tetraethyl ortho silicate, alcohol solvent, and an acid catalyst.

Abstract: The an adhesive composition characterized in that the kisstack, which is defined as the force measured when a sheet coated with the adhesive composition is instantaneously peeled off after being attached, is about 6 N/inch or higher. The composition not only has excellent loop tack but also exhibits high kisstack characteristics, and thus can be widely used for various substrates.

Abstract: A multi-layer pad of double-sided adhesive sheet material with individual pull-tabs.

Abstract: In one embodiment, an anatomical support device includes an elongate body. The elongate body includes a first portion extending along a longitudinal axis between a first end and an oppositely positioned second end, a first wing extending transversely from the first portion, and a second wing extending transversely from the first portion. An adhesive material is positioned on at least a portion of one side of the elongate body. The elongate body is rigid in a first direction extending in-line with the longitudinal axis and is stretchable in a second direction extending transversely to the longitudinal axis.

Abstract: A self-adhesive member for adhering to and covering a portion of a user's skin is disclosed. The self-adhesive member has a backing layer having a self-adhesive coating. The backing layer has a first and a second portion, where the first portion surrounds the second portion, and where the first portion has a first row of slits extending along an outer edge of the backing layer and being distanced a first distance therefrom and the second portion being either void of slits or being provided with fewer slits per area unit than the first portion.

Abstract: A dressing having a multilayer assembly in which dressing includes a polyurethane dressing layer that is adhesively secured over a wound or other location on a user's skin. Label strips that can be incorporated into the dressing. The label strips can include text, indicia, logos, or other markings which are applied to the strip prior to or after application of the dressing.

Abstract: An input device has a film sensor and a cover member having a convex surface. The film sensor includes: a support substrate that has a film-like main body and an extending portion extending from an end of the main body toward the outside; a plurality of electrode portions provided on a surface of the main body; and lead patterns that extend from the main body to the extending portion and are electrically continuous to the plurality of electrodes. A surface of the main body, the surface being on the same side as the plurality of electrode portions, is attached to the convex surface through an adhesive layer. An end adhesive area, in the adhesive layer, positioned on the same side as the extending portion, has lower adhesiveness than a central adhesive area, in the adhesive layer, positioned on the same side as the central portion of the convex surface.

Abstract: A backing sheet for use in a wound dressing includes a semipermeable continuous film laminated to an adhesive-coated apertured layer. The apertured layer is a solid substrate coated with a medically acceptable adhesive. A method of making a backing sheet for use in a wound dressing includes the steps of: forming an adhesive-coated apertured layer by coating a medically acceptable adhesive onto an apertured solid substrate, followed by laminating the adhesive-coated apertured layer to a semipermeable continuous film.

Abstract: An anchorage device includes a substrate extending along a longitudinal axis between a first end having a first bonding area and an opposite second end having a second bonding area. The substrate has a third bonding area between the first and second bonding areas. Kits, systems and methods are disclosed.

Abstract: A perimeter seal device is constructed in three layers to easily convert a non-sealed face mask to a face mask with a perimeter seal. The device has a top and bottom release liner, partitioned for providing the perimeter seal to an existing manufactured mask, with a double-sided adhesive layer in the middle formed with pressure-sensitive adhesive. A pre-cut perimeter portion of the adhesive layer provides the perimeter seal. The construction of the perimeter seal device allows alternate methods for fixing either side of the perimeter portion of the adhesive layer onto a face mask. The opposing side of the adhesive perimeter portion is adhered directly on a wearer's face. The device provides a way to convert a surgical or other non-sealed face mask to a sealed mask.

Abstract: A medical drape comprises at least a bottom ply in the form of a release liner, a middle ply which is adhered to the patient during use of the drape, and a top ply covering the middle ply. The middle ply having an adhesive applied to a bottom surface thereof to removably adhere the bottom ply to the middle ply. The drape comprises a drape body defining top and bottom edges and first and second side edges; a first liner release tab and a carrier lift tab, both tabs being at an edge of the body. The first liner release tab is operable to remove the bottom ply from the middle ply to expose the adhesive of the middle ply. The carrier lift tab is operable to remove the top ply from the middle ply after application of the middle ply to a patient.

Abstract: The present disclosure provides, in one embodiment, a filter device comprising a mouthpiece, a filter assembly in communication with the mouthpiece for filtering air exhaled into the mouthpiece, and an outlet check valve which permits air to be exhaled through the mouthpiece into the filter assembly, and substantially prohibits air from being inhaled from the filter assembly into the mouthpiece.

Abstract: The present disclosure provides, in one embodiment, a filter device comprising a mouthpiece, a filter assembly in communication with the mouthpiece for filtering air exhaled into the mouthpiece, and an outlet check valve which permits air to be exhaled through the mouthpiece into the filter assembly, and substantially prohibits air from being inhaled from the filter assembly into the mouthpiece.

Abstract: A dressing for applying to the skin is characterized in that the adhesive mass is applied discontinuously in a strip or wave and contains an active substance.

Abstract: Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein.

Abstract: A wound dressing assembly includes a wound cover and a carrier. The wound cover has a length and width substantially greater than a height (or thickness), a first major surface, and a second major surface, opposite the first. The first major surface has disposed thereon a wound cover pressure sensitive adhesive comprising a colloidal absorbent, and it is arranged and configured to adhere to mammalian skin during use. The carrier has a length and width substantially greater than a height (or thickness), a first major surface, and a second major surface, opposite the first. The first major surface of the carrier is disposed in facing relation and is removably attached to the second major surface of the wound cover, and it has disposed thereon at least one pressure sensitive adhesive. After application of the wound cover to skin for use, the carrier is removable from the wound cover to leave the wound cover adhered to the skin.

Abstract: The present application is concerned with an improved wound dressing for use in the treatment of skin wounds with some level of exudation, especially for use in those wounds which are infected or under risk of being infected by microorganisms.

Abstract: Provided is a patch for treating skin diseases or alleviating symptoms of the skin diseases involving an exudation of blood proteins, or for absorbing blood proteins exuded to the skin.

Abstract: A medical pressure-sensitive adhesive sheet includes a urethane substrate, an interlayer adhesive layer, an olefin nonwoven fabric, and a pressure-sensitive adhesive layer for pasting in order and has a moisture permeability amount of 2000 g/(m2·24 hours) or more, or the like. In the medical pressure-sensitive adhesive sheet, a thickness of the urethane substrate is a value within the range of from 1 to 10 ?m, a thickness of the interlayer adhesive layer is a value within the range of from 5 to 30 ?m, the olefin nonwoven fabric is constituted with a polypropylene-based thermoplastic elastomer and has a maximum point elongation percentage of a value of 200% or more in the longitudinal direction and the transverse direction, respectively, and a thickness of the pressure-sensitive adhesive layer for pasting is a value within the range of from 5 to 45 ?m.

Abstract: The present disclosure relates to a film dressing having a polymer film and an application system for permitting an improved ease of use of said film dressing. The application system is located on the first side of the polymer film and has at least one first and one second supporting film. At least one first grip strip is formed on the first supporting film and at least one second grip strip is formed on the second supporting film. At least the first grip strip has a grip surface that enables the grip strip to be grasped and the first grip strip at least partially overlaps the second grip strip.

Abstract: Provided is a film dressing that includes a thin plastic film coated with an adhesive, and a carrier layer applied on the plastic film on a side opposite to the adhesive coating. The adhesive coating has a softness of 10-22 mm and a weight per unit area of 50 g/m2 or more.

Abstract: A see-through dressing assembly is presented for use with a reduced-pressure system for treating a wound on a patient using reduced pressure that allows visual observation of the wound during treatment. The dressing assembly includes a bolster for providing a directed force when under reduced pressure, a sealing member for covering the bolster and providing a seal over the bolster and a patient's epidermis, and wherein the bolster and sealing member are formed from see-through materials sufficient to allow perception of color from a point external to the system. Other systems, dressings, and methods are presented.

Abstract: Stretch mark prevention undergarments (1) worn around a woman's abdomen, chest, lower torso, legs, buttocks and other areas for reinforcing elastic fibers in the skin and preventing stretch marks. The stretch mark prevention undergarment has an outer layer (2) made of stretchable material and an inner layer (8) of material made of a non-slip material (9). The non-slip material maintains a constant adherent traction with the skin of a wearer, thereby reinforcing elastic fibers of skin. The inner layer is arranged in a predetermined pattern or design to allow a wearer's skin to breathe through the outer layer of the stretch mark prevention undergarment. The stretch mark prevention undergarment may be in the form of underwear (14), briefs, underpants, panties, leggings (16), corsets, bras (10) or any combination thereof to help prevent stretch marks on various parts of the body.

Abstract: The invention relates to multi-layer elastic thermoplastic films, which consist of at least one layer of thermoplastic polyurethane (TPE-U), at least one further layer of thermoplastic polyurethane which is blended with modified acrylonitrile-butadiene-styrene copolymer (MABS), and optionally at least one support layer of thermoplastic polymer which is incompatible with TPE-U, and to the use thereof.

Abstract: The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a biocompatible adhesive for use in an oral environment, wherein the adhesive is in a non-tacky state when dry and becomes adherent upon contact with liquids.

Abstract: A wound dressing is made of multiple layers and includes a collection chamber that is in fluid communication with a drainage channel. When applied over a wound, the wound dressing provides protection for the wound while allowing air and fluids to evacuate from the wound through the collection chamber and out through the drainage channel. The wound dressing can include a valve that restricts air and fluids from entering the wound, which is beneficial for treating pneumothorax.

Abstract: A bandage and method for securing a tension member comprising a central body and a plurality of tabs disposed about the central body. A tension member may be disposed across or through a slit or aperture of the central body. A body adhesive on the lower surface of the central body may secure the bandage to the patient. The tension member may then be pulled across the upper surface of the central body and a first tab may be folded over and adhered to the tension member and central body. The tension member may then be pulled back across the first tab and a second tab may be folded over and adhered to the tension member and first tab. Likewise, the tension member may then be pulled back across the second tab and a third tab may be folded over and adhered to the tension member and second tab.

Abstract: A self-adhering bandage comprising: a carrier strip; adhesive layer disposed thereon; a gauze strip located approximately centrally on the carrier strip; a release paper covering the gauze strip and held in place by its adhering contact with the adhesive, thus forming a laminate; and an indicia incorporated in the adhesive layer that is transferable from the adhesive layer and a user's skin, when the bandage is removed from the user's skin.

Abstract: A bioadherent composition includes a first mixture containing a plurality of reactive members of a specific binding pair, said reactive members being bound to a ligand capable of binding a receptor on biological tissue, and a second mixture containing a plurality of complementary reactive members of the specific binding pair, said complementary reactive members being bound to a ligand capable of binding a receptor on biological tissue, said reactive members capable of forming covalent bonds with said complementary reactive members via a reaction selected from Huisgen cycloaddition reactions, Diels-Alder reactions, and/or thiol-alkene reactions. A method for bonding biological tissue involves utilizing the bioadherent composition.

Abstract: A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film.

Abstract: An in situ film-forming methyl acetate-based solution of at least one absorbable, segmented block copolymer with amorphous and semi-crystalline segments contains at least one bioactive agent which exhibits antimicrobial, anti-inflammatory, antiviral, anesthetic, hemostatic, and/or antineoplastic activity. The absorbable polymers can be a polyaxial copolyester, polyether-ester and polyether-ester urethane. The solution can be applied (e.g., sprayed or swabbed) onto animal and human skin or accessible body cavities to prevent or treat one or more disorders preventable or treatable by the bioactive agent therein.

Abstract: The present invention is drawn to adhesive peel-forming formulations for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a peel-forming agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent, wherein the non-volatile solvent system has a solubility for the drug that is within a window of operable solubility for the drug such that the drug can be delivered at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified peelable layer after at least a portion of the volatile solvent system is evaporated.

Abstract: A bandage can be used to secure a needle to an access site so as to prevent unintended movement or withdrawal of the needle from the access site during administration of a treatment to a patient. After treatment, the needle can be removed by manipulating a portion of the bandage. Another portion of the bandage can be maintained in position over the access site during needle removal and can be used to promote clotting of the site after needle removal. The bandage may include a clotting agent, a hemostasis pad, and/or a clot-promoting structure. Additionally or alternatively, finger pressure can be applied to the access site through the bandage. For example, the bandage may include a viewing window without any adhesive to allow visual monitoring of the access site during treatment. Finger pressure may be applied to the viewing window and thereby to the access site during and after needle removal to encourage hemostasis.

Abstract: Liquid adhesive coating materials are prepared that protect surfaces, such as medical devices and biological surfaces, including skin and mucous membranes, from pressure, shear, and friction. The liquid coating materials utilize an amphiphilic siloxysilane/hydroxyalkyl ester polymer-containing coating material dissolved in a volatile solvent, with or without an antimicrobial agent, where when the polymer coating is formed after solvent evaporation and is folded against itself or placed against another material, the surface of said coating does not adhere, while the bottom of the coating remains attached to the original surface.

Abstract: An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a wound dressing, in one example used to cover an indwelling central venous catheter or other catheter. A bacteria detection apparatus includes a barrier membrane, a permeable membrane for placement proximate a wound or a catheter insertion site, and an indicator between the barrier membrane and the permeable membrane for indicating the presence of bacteria proximate the permeable membrane. A method of using a bacterial growth detection apparatus is also provided.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: An in situ film-forming sprayable methyl acetate-based solution of at least one absorbable, low-crystallinity, segmented copolymer contains at least one bioactive agent, which exhibits antimicrobial, anti-inflammatory, antiviral, anesthetic, hemostatic, and/or antineoplastic activity. The absorbable polymers can be a polyaxial copolyester, polyether-ester and polyether-ester urethane and the bioactive solution thereof can be applied onto animal and human skin or accessible body cavities to prevent or treat one or more disorder susceptible to the bioactive agent therein.

Abstract: The disclosed conformable coating provides a highly durable and resilient film useful for protecting and repairing surfaces such as skin and mucous membranes. A conformable coating composition comprises an elastomer, a volatile liquid, wherein the volatile liquid is at least 40% wt. of the total composition and the composition has a viscosity less than 1,000 cps. Disclosed is a conformable film that comprises an elastomer on a substrate, wherein the coating weight is from 1 to 30 mg/in2, and wherein the film has less than 75% failure at 100% elongation.

Abstract: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: The present invention relates to compositions of cyanoacrylate monomer, a method of improving the viscosity and the curing speed with a single additive and a process of providing sterilized cyanoacrylate adhesive compositions for application in the medical field.

Abstract: The invention relates generally to thin-film adhesive materials suitable for various applications. In particular, the present invention provides pliable viscoelastic thin-films configured to form strong water-resistant adhesive bonds to various surface types.

Abstract: A method of forming and the resulting membrane composition for securement to a patient's bone or tissue to reduce the formation of tissue adhesions following a surgical procedure comprises a first component and a second component. The first component comprises a hydrogel including at least one crosslinked polymer. The second component comprises a textile component. The composition has a thickness between about two tenths of a millimeter (0.2 mm) to about six tenths of a millimeter (0.6 mm), a suture retention strength between about one Newton (1 N) to about thirteen Newtons (13 N), a static coefficient of friction between about one hundredth (0.01) and about one-half (0.5), a kinetic coefficient of friction between about one hundredth (0.01) and about one-half (0.5) and a flexibility of less than thirty millimeters (30 mm) bend length. A method of reducing the occurrence of tissue adhesions following surgery comprises applying the membrane composition to a surgical site.

Abstract: A device for protecting an area of skin of a human body includes a plate. The plate includes a first face covered by an external layer and a second face opposite the external layer. The second face is configured to be applied onto an area of skin to be protected. The plate also includes a protective part made of a polymer gel and at least one adhesive part made of a polymer gel. The protective part is configured to ensure mechanical protection of the area to be protected and the adhesive part is configured to come into contact with the skin. The adhesive part has an adhesive power greater than an adhesive power of the protective layer to hold the plate on the area to be protected.

Abstract: A device for recording and transferring the contours of a wound or opening in tissue of a human being to an adhesive wafer of a wound appliance is provided. The device includes a transparent polymer sheet having a first and a second surface, the first surface being non-adhesive and facing the wound or opening and the second surface having a central portion and an edge portion, with the edge portion being provided with an adhesive layer. The device is placed over the wound or opening and the contours are traced on the central portion of the device. The adhesive layer on the second surface is then adhered to the wafer so that the drawn image contacts the wafer and is directly imparted to the wafer.

Abstract: A medicated patch is provided which is covered with a liner that enables one to remove the liner unconsciously and readily without losing the initial stickiness of the medicated patch. The external medicated patch includes a backing, an aqueous adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that is larger in size than the surface of the drug-containing matrix to which the liner is attached. The liner larger in size than the surface of the drug-containing matrix to which the liner is attached includes an unattached area that extends from the surface of the drug-containing matrix, or an unattached slack portion that projects upward from the surface of the drug-containing matrix at a position on the surface of the drug-containing matrix.

Abstract: The invention relates to a thin film dressing having a release liner which is able to support the dressing during application. The resilience or stiffness of the release liner is higher than the resilience or stiffness of the dressing so as to enable the control of the dressing during application. The invention further relates to a method of application of the thin film dressing where a minor part of the dressing initially is applied to the skin afterwards the dressing is folded backwards so the release liner faces upwards. Finally, the remaining part of the dressing is applied by pushing the release liner forwards in a rolling motion thereby rolling the dressing onto the skin. This dressing assembly allows the dressing to be applied by using only one hand.

Abstract: The invention provides wound dressings comprising an absorbent (porous) hydrogel composition comprising a foam portion which comprises a flexible plasticized hydrophilic polymer matrix having an internal cellular structure, and a continuous portion which comprises a flexible plasticized hydrophilic polymer matrix having relatively continuous internal structure. The continuous portion of the hydrogel composition includes apertures providing fluid flow communication through the continuous portion between an external surface of the continuous portion and the foam portion whereby the foam portion can take up external water or other fluid into the cellular structure through the apertures of the continuous portion. The continuous portion of the hydrogel composition may be tacky to the skin, allowing its use as a bioadhesive.

Abstract: Disclosed is a two-component device for closing a laceration or incision. The device includes a first component comprising a first adhesive-backed anchoring member and one or more first connecting members extending from one edge thereof in a first direction. Also included is a second component comprising a second adhesive-backed anchoring member and one or more second connecting members extending from one edge thereof in a second direction generally opposite to the first direction. Means for attaching the one or more first connecting members to the second anchoring member and means for attaching the one or more second connecting members to the first anchoring member is also provided. The attachment of the connecting members to the anchoring members forms attached and bridging portions of the one or more connecting members, the attached portions being attached to an anchoring member, and the bridging portions spanning the over-laceration area between the first and second anchoring members.