Abstract: A negative pressure tissue treatment system useful for negative pressure therapy includes a drape, a gasket material, a reactor housing, a reactor, and any fluid connection(s). The drape covers the skin of a patient and maintains negative pressure under the drape. The gasket material cooperates with the drape to define an enclosed volume that is scaled by the gasket material. The reactor housing defines a closed chamber in fluid communication with the enclosed volume, and the reactor is disposed in the reactor housing. The reactor consumes oxygen from a system volume defined by the enclosed volume, closed chamber, and/or any fluid connection(s). As a result of the oxygen consumption, the system volume is reduced to between about 95% to about 80% of the initial system volume.

Abstract: A medical dressing includes: a lower support film; a release film; and an adhesive sheet part (110) for application, which is placed on the release film (200) and is attached to the skin, wherein the release film (200) consists of a release film part (210) for fixing and a separable release film part (220) to be separated therefrom by a cutting line (211) formed on the release film part (210) for fixing, so that a predetermined region of the separable release film part is positioned to overlap with the bottom surface of the adhesive sheet part (110), thereby allowing, during separation of the separable release film part (220) from the release film part (210) for fixing, separation together with the adhesive sheet part (110) for application, and the area of the separable release film part (220), which overlaps with the bottom surface of the adhesive sheet part (110), is relatively smaller than the area of the separable release film part, which does not overlap with the adhesive sheet part (110).

Abstract: In a first aspect, there is a system including: a sheet configured to be applied to the skin of a patient over a wound or scar bed; a device that is separate from the sheet and that is configured to be used to massage the sheet to cause: (1) static charging of the sheet, and (2) physical massaging of the wound covered by the sheet.

Abstract: A body support wrap adapted to encompass a body article of a user while elastically encompassing and supporting a fluid communication element, the body support wrap includes first and second flexible elastomeric surrounding sidewalls that are adjacent to one another and offset on an upper end forming a mouth opening and the first and second sidewalls are evenly displaced on a lower end forming a closed attachment, wherein an interior pocket is formed therebetween the first and second sidewalls that the fluid communication element is disposed through the mouth opening, wherein operationally via the first and second sidewalls elasticity the fluid communication element is held anyplace within the interior pocket in multiple positions adjacent to the user for the convenience and comfort of the user.

Abstract: A manifold for treating a tissue site may include a first side and a second side opposite the first side. The second side of the manifold may be configured to face the tissue site, and to contract a greater amount than the first side of the manifold when exposed to a compressive force. In some illustrative examples, the manifold may be configured to distribute reduced pressure to the tissue site, and to contract when exposed to the reduced pressure. The manifold may be suitable for use with dressing assemblies, treatment systems, and methods for treating a tissue site.

Abstract: A medical system includes an ostomy appliance, a monitor, and a docking station. The monitor has a processor for processing data and a memory adapted to store the data. The docking station is provided to charge the monitor and/or transfer data from the monitor.

Abstract: A dressing interface for connecting a negative-pressure source to a dressing may have a coupling member comprising an aperture, a first adhesive region having a first region peel strength, and a second adhesive region having a second region peel strength less than the first region peel strength. The dressing interface may further have a flange coupled to the coupling member, and a conduit housing coupled to the flange and extending through the aperture in the contact layer.

Abstract: A microbial detection device and methods of use are provided. The device comprises a water-proof pouch that includes a first wall portion, a second wall portion, and a porous membrane filter disposed in the pouch between the first and second wall portions. The filter membrane divides the pouch into first and second compartments. A dry, cold water-soluble gelling agent is adhered to the pouch in the first compartment and an absorbent pad is disposed in the second compartment. A release liner removably adhered to the first adhesive layer.

Abstract: A packaging material web stock is provided. The packaging material web stock can include first and second plies overlaid and sealed to each other at a plurality of seals that include a plurality of transverse seals extending transversely across the plies, wherein a plurality of interior cavities are defined between the plies and the transverse seals, the first and second plies arranged in a web that includes a plurality of packaging units arranged longitudinally in a series along the web, wherein the first and second plies form walls of the packaging units, and at least some of the packaging units include at least one of the interior cavities, and an expansion material disposed in the interior cavities in an unexpanded configuration, wherein the expansion material is arranged within the inner cavities such that, when expanded to the expanded configuration, the expansion material is configured to provide cushioning in the walls.

Abstract: A wound dressing having a chromic material responsive to at least one stimuli. In one or more embodiments, a plurality of individual liquid expandable articles introduce the chromatic material to the wound. The individual liquid-expandable articles release stored mechanical energy and mechanically expand into expanded articles upon contact with a liquid associated with the wound. In response to the chromic material receiving the at least one stimuli the chromic material provides a color change evidencing how long the expanded articles have been in contact with the wound and where the expanded articles are within the wound. In one or more embodiments, determinations may be made about removing the expanded articles from the wound based on the color of the chromic material.

Abstract: A method for using a patch for pain relief, and the patch are provided. The method includes determining a location corresponding to source of pain in a body, and disposing a patch including a reactive capacitance material at one of a location corresponding to source of pain or a location between location corresponding to source of pain and a brain. The patch is disposed adjacent to the surface of the body. The reactive the capacitance material comprises conductive particles dispersed in a binder so that at least a majority of the conductive particles are adjacent to, but do not touch, one another. The patch includes a first outer layer, a reactive capacitance layer, and a second outer layer. The reactive capacitance layer is disposed between the first outer layer and the second outer layer. The reactive capacitance layer is formed of the reactive capacitance material.

Abstract: A wound dressing (10) for covering a wound, including an absorbent layer (12) with an upper side (14) and a lower side (18), the upper side being coated with a protective layer (16). At least one cut (26) and at least one perforated dividing line (28) is incorporated into the absorbent layer (12) to form at least one segment (30, 32, 34, 36), which can be separated from the absorbent layer (12) without tools. An adhesive section (40) originates from the protective layer (16) for covering the at least one cut (26) and the at least one perforated dividing line (28).

Abstract: An insertion site for a cannula (23) on a skin (8) of a patient is prepared by applying a skin cover unit (1) of the type comprising a window (2) and a wall (3) in extension of the window (2) and connected to the window (2) by a bending region (4) for bending the wall (3) into an angled orientation relatively to the window (2); wherein the win-dow (2) comprises a stabilizing frame (5) and an ultrasonic-transparent flexible sheet (6) within the frame (5). The flexible sheet (6) is glued onto the skin (8) of the patient for ultrasonic investigation of the insertion site through the flexible sheet (6). By bending the bending region (4), the angular orientation of the wall (3) is adjusted into an approximately perpendicular orientation relatively to the window (2) for separating the insertion site from the flexible sheet (6) by the wall (3).

Abstract: A bridge for facilitating delivery of reduced pressure to a wound site of a patient includes a reduced pressure lumen configured to be fluidly coupled to a reduced pressure source, and a secondary pressure lumen configured to be fluidly coupled to a secondary pressure source at a first end and to the reduced pressure lumen at a second end, thereby facilitating flow of exudate removed from the wound site by the reduced pressure source using the secondary pressure source. The reduced pressure lumen or the secondary pressure lumen includes a skin contacting surface formed of a moisture permeable membrane comprising an air-impermeable film that allows moisture from the patient to transfer into the reduced pressure lumen or secondary pressure lumen through the moisture permeable membrane while maintaining reduced pressure at the wound site.

Abstract: A medical device includes a monitor having a processor for processing data and a memory adapted to store the data, and a medical appliance attachable to skin of a user. The medical appliance includes an adhesive, an electrode assembly coupled to the medical appliance and located distal to the adhesive, a top layer coupled to the medical appliance and located distal to the electrode assembly, and a monitor interface connected to the top layer. The monitor interface includes a mechanical coupling part to mechanically attach the monitor to the medical appliance and an electrical coupling part with a terminal that electrically connects the monitor to the electrode assembly when the monitor is attached to the medical appliance.

Abstract: A topical nerve stimulator patch and system are provided including a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.

Abstract: A wound closure device and a method of its use are disclosed. The wound closure device includes a wound closure strip, the wound closure strip including a wound-facing side and a top side, the wound-facing side comprises an adhesive applied over at least a portion of the wound facing side of the wound closure strip and a non-symmetric, two-part release liner assembly detachably adhered to the adhesive, the release liner assembly including a first section and a second section with the second section including a wound closure strip-free portion forming a tab. In an alternate embodiment, the device is multi-segmented and the wound closure strip may be coextensive with the release liner assembly.

Abstract: A cosmetic wipe for applying or removing a cosmetic formula is described. In an embodiment, the cosmetic wipe includes a thin body. The cosmetic wipe also includes an edge of the body defining a perimeter of the body and a slit located in the thin body offset from the edge of the body. The slit may be configured to increase an edge length of the body.

Abstract: A wound dressing including a layer in the form of a strip and including gel-forming fibers, the strip having longitudinal lines of stitches formed from a thread and transverse lines of stitches formed from a thread. In certain forms, the wound dressing includes at least one stitch free column.

Abstract: A customizable cushioning device for supporting an anatomical region of a patient can include a main body. The main body can have an intact base and a plurality of removable pillars. The plurality of removable pillars can be disposed on the intact base. The main body can include a first portion and a second portion. The first portion can have a first flexibility. The second portion can have a second flexibility. The first flexibility is different from the second flexibility.

Abstract: A negative pressure wound therapy device includes a piezoelectric pump, a state detector configured to detect a state of the pump, and a control circuit configured to transmit a first control signal for a first period having a first RMS voltage greater than or equal to a threshold voltage at which driving the pump for a second period greater than the first period can cause the pump to emit sound at a magnitude greater than a sound threshold; receive a first indication of the state; determine if the pump is in a leak condition; transmit, responsive to the pump not being in the leak condition, a second control signal having a second RMS voltage less than the first RMS voltage; and transmit, responsive to the pump being in the leak condition, a third control signal having a third RMS voltage greater than the second RMS voltage.

Abstract: A micro-negative pressure foam dressing and a manufacturing method thereof is disclosed, the dressing comprises a exothermic agent layer, an isolation component covering on the exothermic agent layer, an elastic memory piece disposed under the exothermic agent layer, a liquid absorbing negative pressure pad disposed under the elastic memory piece, a contact layer disposed under the liquid absorbing negative pressure pad, a sealing film disposed between the liquid absorbing negative pressure pad and the contact layer, and a bottom release film disposed under the contact layer; and in this invention, heat generated by a exothermic agent layer causes an elastic memory piece to expand downward to compress a foam layer, and after the heat dissipates completely, a micro-negative pressure is generated since a sealed environment is formed by a sealing film, a contact layer and a wound surface without a need for the VSD negative pressure technology.

Abstract: Various methods, systems, and devices relate to identifying a sepsis risk of an individual based on a dwell time of an invasive device in the individual. An example method includes receiving, from multiple transceivers, location data indicating first signals transmitted between the multiple transceivers and a tag attached to the invasive device. A location of the invasive device can be identified based on the location data. The dwell time can be determined based on the location. In certain examples, a second signal indicating the sepsis risk can be generated.

Abstract: The present invention is directed to a method of forming a laminate absorbent structure, and a resulting package containing a single continuous running web of the laminate material. Notably, formation of the material is effected by blending a curtain of adhesive fibers with a curtain of particulate material, and depositing the mixture on a moving substrate, preferably provided in the form of a tissue layer. A second substrate, also preferably comprising a tissue layer, is applied on top of the deposited mixture, and pressure applied to form the laminated structure. Notably, attendant to packaging of the laminated material, adjacent layers of the material tend to nest into one another, to form a sandwich in which the density of the material in the package is more than 1.5 times the density of the material after its removal from the package.

Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a negative pressure source, a wound dressing configured to be positioned over a wound, and optionally a canister configured to store fluid aspirated from the wound. The negative pressure source, wound dressing, and canister (when present) can be fluidically connected to facilitate delivery of negative pressure to the wound. The system can be configured to automatically detect whether the canister is positioned in the fluid flow path between the negative pressure source and the dressing while negative pressure source provides negative pressure to the wound dressing. Operation of the system can be adjusted based on whether presence of the canister has been detected. For example, a value of an operational parameter can be set to indicate that the canister is present.

Abstract: Devices, kits and methods described herein may be for treatment to skin, including but not limited to wound healing, the treatment, amelioration, and/or prevention of scars or keloids. An applicator and/or tensioning device may be used to apply a dressing to a subject. The applicator and/or tensioning device applies and/or maintains a strain in an elastic dressing, wherein at least some of the strain is out-of-plane or at a non-orthogonal, non-parallel and non-aligned orientation to other strains in the dressing.

Abstract: A wound dressing makes use of a saccharide, such as Manuka honey, in combination with collagen in order to suppress the efficacy of matrix metalloproteinases enzymes (“MMPs”) present in chronic wounds. The mixture is applied to an absorbent surface that is designed to absorb the mixed saccharide only partially.

Abstract: In some embodiments, the present invention is directed to an actuator which includes at least the following: a pre-stretched electro-active polymer film being pre-stretched in a single or biaxial planar directions; at least one first semi-stiff conductor attached to a first surface of the pre-stretched electro-active polymer film, wherein the first surface is parallel to the single or biaxial planar stretch directions; at least one second semi-stiff conductor attached to a second surface of the pre-stretched electro-active polymer film, wherein the second surface is opposite to the first surface; where the semi-stiff conductors are configured to: fix the pre-stretched electro-active polymer film in a pre-stretched state and allow the pre-stretched electro-active polymer film to expand; a pair of mechanical connectors coupled to each end of an active region of the pre-stretched electro-active polymer film.

Abstract: Systems, assemblies, and methods for providing negative-pressure therapy to a tissue site are described. The system can include an absorbent and a sealing layer configured to cover the absorbent. The system can also include a blister fluidly coupled to the absorbent. The blister may have a collapsed position and an expanded position. A first check valve may be fluidly coupled to the absorbent and the blister and configured to prevent fluid flow from the blister into the absorbent if the blister is moved from the expanded position to the collapsed position. A second check valve may be fluidly coupled to the blister and the ambient environment and configured to prevent fluid flow from the ambient environment into the blister if the blister is moved from the collapsed position to the expanded position.

Abstract: A device and method are provided for therapy and treatment of biological tissue such as muscle, tendon, and ligament tissue, by use of a device and method in which therapeutic vibrational frequency resonance patterns are transmitted to tissues of a patient. The resonance frequencies originate from many resonance domains, including vitamins, minerals, herbs, amino acids, and fatty acids. Each domain includes therapeutic frequency resonance patterns. These resonance patterns may be passively excited and transmitted to a patient to enhance tissue function, to decrease the normal rehabilitation time of damaged tissue, and provide therapeutic benefits for muscle tissue dysfunction. Therapeutic frequency resonance patterns may also be actively excited by a delivery mechanism that uses electromagnetic or mechanical waves to interact with the device. The actively excited device transmits the therapeutic frequency resonance patterns to the patients for similar enhancements and therapeutic benefits.

Abstract: A multilayer nanofiber sheet (10) includes: a nanofiber layer (11) including nanofibers which comprise a water-soluble polymer compound; a substrate layer (12) arranged on one surface side of the nanofiber layer (11); and a water-insoluble porous layer (13) arranged on the other surface side of the nanofiber layer (11). The three layers are layered, and the multilayer nanofiber sheet is used in a state in which a surface thereof on the porous layer side is arranged so as to face a surface of an object. Preferably, the three layers are layered in a fixed state. Preferably, the porous layer (13) has a thickness of from 3 to 1000 ?m.

Abstract: A wavelength converting bandage including a substrate with an external surface and an internal surface. The wavelength converting bandage includes a plurality of quantum dots, each quantum dot individually sized to emit light within a wavelength range of 613 nm to 846 nm, defined as converted light. The wavelength converting bandage includes at least a portion of the substrate constructed to adhere to skin. The substrate may receive ambient light from the environment on the external surface and may emit converted light toward the skin.

Abstract: Disclosed are a medical fiberous structure and a method for preparing the same, wherein the medical fiberous structure comprises calcium carboxymethyl cellulose and a chitosan compound, at least one of the calcium carboxymethyl cellulose and the chitosan compound having a fibrous shape.

Abstract: A device-securing overlay includes a wearable strip that has a controlled applicant to fit over at least a portion of a wearable device, while an adhesive on an under portion of the wearable strip is placed in contact with at least a top portion of an outer rim of the wearable device as well as a surface upon which the wearable device is placed, without covering portions of the wearable device that require ventilation or an unobstructed view.

Abstract: An oxygen distributor (1) positionable, in use, in a wound for supplying oxygen to the wound has an oxygen delivery area (17) for, in use, receiving a supply of oxygen. At least one tube (19A) extends from the oxygen delivery area, having a tube wall with an oxygen-permeable, liquid-impermeable section. Oxygen delivered to the oxygen delivery area can flow away from the oxygen delivery area along the, or each, tube.

Abstract: Disclosed is a medical dressing having a carrier material and a composite material. The composite material includes oil droplets dispersed in a matrix. The matrix includes one or more cellulose derivatives and nanocellulose.

Abstract: Devices, systems, compositions and methods for long term or prolonged transdermal administration of an active agent are provided.

Abstract: A transdermal absorption preparation precursor 50 containing a release liner 10 containing one first valley fold part 1, one or two first mountain fold parts 2, and a first base line L1 and a second base line L2 on one side and the other side apart from the first valley fold part 1 as a line of demarcation and at an approximately equal distance from the first valley fold part 1, wherein at least one of the first base line L1 and the second base line L2 is a fold line of the first mountain fold part 2, and a drug-containing layer 3 having a center line laid on the first base line L1 and an adhesive layer 4 having a center line laid on the second base line L2 on the release liner 10.

Abstract: A system including a first base sheet, a second base sheet, a first plurality of individual strip sections extending out of said first base sheet, a second plurality of individual strip sections extending out of the second base sheet, wherein said first plurality of individual strip sections are operable for engagement and disengagement with said second base sheet and wherein said second plurality of individual strip sections are operable for engagement and disengagement with said first base sheet to enable and maintain wound closure and allow application of antibiotics to prevent and/or treat wound infection or application of other topical agents without removing and replacing the system.

Abstract: A subcutaneous sling for neck lift surgery. The sling comprises a sling body, shaped to fit in a submental triangle of a patient undergoing neck lift surgery, comprising a narrow anterior edge for anchoring near the chin of the patient. The sling comprises two lateral sling extensions, each coupled to a respective side edge of two sides of the sling body, each projecting away from the center of the sling body in a posterior lateral orientation of between 45 and 90 degrees from the anterior-posterior axis, and curved slightly towards the narrow anterior edge to fit the submandibular triangle and extend to near each ear of the patient. The sling body is at least 4 centimeters long in the anterior-posterior dimension, and the ends of the two lateral sling extensions are at least 14 centimeters distant from each other.

Abstract: A method for using a patch for pain relief, and the patch are provided. The method includes determining a location corresponding to source of pain in a body, and disposing a patch including a reactive capacitance material at one of a location corresponding to source of pain or a location between location corresponding to source of pain and a brain. The patch is disposed adjacent to the surface of the body. The reactive the capacitance material comprises conductive particles dispersed in a binder so that at least a majority of the conductive particles are adjacent to, but do not touch, one another. The patch includes a first outer layer, a reactive capacitance layer, and a second outer layer. The reactive capacitance layer is disposed between the first outer layer and the second outer layer. The reactive capacitance layer is formed of the reactive capacitance material.

Abstract: The methods disclosed herein of generating three-dimensional lattice structures and reducing stress shielding have applications including use in medical implants. One method of generating a three-dimensional lattice structure can be used to generate a structure lattice and/or a lattice scaffold to support bone or tissue growth. One method of reducing stress shielding includes generating a structural lattice to provide sole mechanical spacing across an area for desired bone or tissue growth. Some examples can use a repeating modified rhombic dodecahedron or radial dodeca-rhombus unit cell. Some methods are also capable of providing a lattice structure with anisotropic properties to better suit the lattice for its intended purpose.

Abstract: A wound dressing is in the form of a strip or a ribbon. The strip or ribbon is made of gel-forming fibers and has longitudinal lines of stitches formed from a thread and transverse lines of stitches formed from a thread.

Abstract: Reduced pressure wound therapy is performed on a sacral region of a patient using an adhesive dressing comprising a flexible planar layer and a non-planar fold-sealing region configured to seal to the intergluteal cleft of a patient. The fold-sealing region is located on an outer edge of the adhesive dressing and comprises a tapered configuration.

Abstract: A transdermal administration device including an administration member including a substrate having first and second surfaces, and a projection protruding from the first surface, a first adhesive sheet adhered to and extending outward from the second surface, a second adhesive sheet adhered to and extending outward from the first adhesive sheet, and a cover including a main body and a flange extending outward from an edge of the main body. The main body and the flange form a structure body including a remaining portion which includes at least a portion of the flange and is configured to remain on the second adhesive sheet, a tear-off portion which includes at least a portion of the main body and is configured to be separated from the remaining portion, and a tear-off assistance portion configured to facilitate formation of a cut for separating the tear-off portion from the remaining portion.

Abstract: An orthopedic or prosthetic support including at least three layers that allows for aeration and cushioning of the enclosed area is described herein. The orthopedic or prosthetic support includes an inner cushioning layer which is compressed against the skin in use. An intermediate scaffolding layer is situated substantially parallel to the inner cushioning layer and is maintained in spaced apart relationship with the inner cushioning layer by spacer members. An exterior layer overlays the intermediate scaffolding layer and may be either a flexible breathable fabric such as velvet or a thermoplastic with a plurality of perforations. The inner cushioning layer and the intermediate scaffolding layer include a plurality of perforations providing air pathways through the two layers. The grid-like arrangement of spacer members also define air passages between the inner and intermediate layers which further enhance circulation of exterior air to the skin covered by the orthopedic or prosthetic support.

Abstract: Disclosed herein are systems and methods for providing reduced or negative pressure, and more particularly cyclical reduced pressure, to treat a wound. The system can include a wound dressing, a fluid collection container, a suction source, filters, and conduits. In addition, the system can include a control device and sensors. The sensors may be configured to monitor certain physiological conditions of a patient such as temperature, pressure, blood flow, blood oxygen saturation, pulse, cardiac cycle, and the like. Application of cyclical reduced pressure between two or more values below atmospheric pressure may be synchronized with the physiological conditions monitored by the sensors. Certain embodiments of the system utilize an air reservoir and one or more valves and pressure sensors or gauges to allow for rapid cycling of the level of reduced pressure within the wound dressing between two or more reduced pressure values.

Abstract: Methods of handling adhesive laminate patches. A first article, passed over a first supporting structure, includes disconnected adhesive laminate patches adhered to a first web, each patch being aligned over and adhered to a tab. A second web can be passed over a second supporting structure that is separated from the first supporting structure by a gap. The first article can be passed over the first supporting structure to lift a leading portion of a first tab and a first patch off of the first web together, such that the first tab facilitates transfer of the first patch across the gap. The first patch can then be adhered to the second web; and the second web can be advanced to transfer the first patch, and first tab, onto the second web to form a second article comprising patches aligned over tabs on the second web.

Abstract: A wound dressing apparatus includes a wound dressing member dimensioned for positioning relative to a wound bed. The wound dressing member including an internal vacuum reservoir and has a port in communication with the vacuum reservoir for applying subatmospheric pressure to the vacuum reservoir to facilitate removal of fluid from the wound bed. The wound dressing member includes a visual pressure indicator associated therewith for indicating a level of pressure within the vacuum reservoir. The visual pressure indicator includes color indicia having a plurality of colors corresponding to a condition of the pressure within the vacuum reservoir. The wound dressing member includes a lower absorbent member positionable adjacent the wound bed and an upper member which at least partially defines the vacuum reservoir. At least one of the top member and the lower absorbent member has the visual pressure indicator mounted thereto.

Abstract: Disposable antifouling covers for geophysical survey equipment. At least of example embodiments are methods including deploying marine geophysical survey equipment. The deploying may include: installing a disposable antifouling cover of plastic material on a portion of the marine geophysical survey equipment, wherein the disposable antifouling cover occludes a majority of an exterior surface of the portion of the marine geophysical survey equipment; and placing the marine geophysical survey equipment in a body of water.