System For Adhesive Layer Release (e.g., Release Sheet) Patents (Class 602/57)
  • Patent number: 10398802
    Abstract: A tissue bonding article includes a flexible material, an adhesive substance applied over at least a portion of a bottom side of the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: September 3, 2019
    Assignee: Ethicon, Inc.
    Inventors: Jerry Y. Jonn, Julian Quintero, Glenn Hoskin
  • Patent number: 10172412
    Abstract: This application discloses shoe inserts which are configured such that a user may expose one or more adhesive layers while the cushioning shoe insert is maintained at an optimal location within a shoe, thereby securing the cushioning shoe inserts precisely at the optimal location. Moreover, this application discloses shoe inserts which are designed to distribute necessary support forces, e.g. through a foot chock, thereby mitigating or eliminating uncomfortable levels of localized pressure.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: January 8, 2019
    Inventor: Carlene Pride
  • Patent number: 9877871
    Abstract: Wound bed preparation in a skin wound area can be carried out by using a hydrogel sheet, wherein the hydrogel sheet is prepared by spreading a hydrogel containing a water-soluble polymer, glycerin, and water on a two-layered laminated film consisting of a polyurethane film and a hydrophobic fiber and the moisture permeability of the hydrogel sheet is 200-2000 (g/m2/24 h).
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: January 30, 2018
    Assignee: TEIKOKU SEIYAKU CO., LTD.
    Inventors: Yukiko Inamoto, Takashi Kamakura, Makoto Takahashi, Takehiko Ohura
  • Patent number: 9839560
    Abstract: An adhesive device used as a wound dressing, ingredient delivery device or IV hold-down in which inadvertent edge release of these devices along the periphery of the polymeric film layer is minimized when the handling layer, which is adhered to the polymeric film layer, is removed after application of the polymeric film layer to the patient.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: December 12, 2017
    Assignee: Corium International, Inc.
    Inventors: Michael G. Marcoux, David R. Johnson, Steven R. Klemm
  • Patent number: 9539318
    Abstract: The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: January 10, 2017
    Assignee: DBV Technologies
    Inventors: Christophe Dupont, Pierre-Henri Benhamou, Bertrand Dupont
  • Patent number: 9452079
    Abstract: A wafer adapted for use with an ostomy appliance includes a backing layer, an adhesive layer applied to the backing layer and providing an adhesive surface, and a liner system disposed over an entirety of the adhesive surface. The adhesive surface includes a mid-section. The liner system includes a first side liner placed on a first lateral side of the mid-section of the adhesive surface, a second side liner placed on a second lateral side of the mid-section of the adhesive surface, and a third middle liner having folded edge portions and covering the mid-section of the adhesive surface.
    Type: Grant
    Filed: November 27, 2014
    Date of Patent: September 27, 2016
    Assignee: Coloplast A/S
    Inventors: Mads Lykke, Esben Stroebech, Anders Bach, Astrid Toftkaer, Hasse Buus, Tom Kongebo
  • Patent number: 9314312
    Abstract: A therapeutic device has a bridge portion adapted for releasable adherence to a patch of skin so as to lift the patch of skin above a sensitive underlying treatment site in reducing discomfort or pain associated with tissue compression at the treatment site. The bridge portion is elevated above the treatment site with an exposed adhesive facing the patch of skin to be lifted and/or stretched outwardly. With the application of pressure to elastically deform the device from its original neutral configuration, the bridge portion is brought into contact with the patch of skin, adhering the skin to the adhesive. When the pressure is removed, the device rebounds and generally reassumes its original configuration with the bridge portion lifting the attached patch of skin.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: April 19, 2016
    Assignee: CARPAL AID, LLC
    Inventor: Joseph Nazari
  • Publication number: 20150133844
    Abstract: An elongate adhesive article having a length substantially greater than a width includes a backing layer having an adhesive layer and a single weakened region formed of a removable strip of backing layer that is oriented substantially perpendicular to the article length. The removable strip of backing layer is at least partially defined by a pair of lines of weakness separated by a gap of between about 2 and about 15 mm. The elongate article may include an absorbent pad in the form of an adhesive bandage or sticking plaster. A method of using such an elongate article includes the steps of applying the article to the skin of a mammal, removing a predefined strip from the article; and removing the remainder of the article from the skin.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 14, 2015
    Applicant: Johnson & Johnson Consumer Companies, Inc.
    Inventor: Shannon Montulet
  • Patent number: 9000251
    Abstract: A wound dressing is made of multiple layers and includes a collection chamber that is in fluid communication with a drainage channel. When applied over a wound, the wound dressing provides protection for the wound while allowing air and fluids to evacuate from the wound through the collection chamber and out through the drainage channel. The wound dressing can include a valve that restricts air and fluids from entering the wound, which is beneficial for treating pneumothorax.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: April 7, 2015
    Assignee: Combat Medical Systems, LLC
    Inventors: Christopher Murphy, Corey Russ, Jim McGuire
  • Patent number: 8985118
    Abstract: This application presents retention devices that afford the user quick and easy placement. These retention devices may accommodate objects of various shapes and sizes. The device provides sturdy means for retaining and securing an object to a surface without the need to handle and position flaps of tape. The device allows easy removal from the retained object without adhesives directly contacting or damaging it sensitive surfaces. The retention described here may be used to quickly secure anatomic structures during operations, such as securing the penis against the abdomen during vasectomy, without causing discomfort or damage to sensitive skin during application or removal.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: March 24, 2015
    Assignee: Alred E. Mann Institute for Biomedical Engineering at the University of Southern California
    Inventors: Afshin Nadershahi, Ricardo G. Hahn
  • Publication number: 20150073930
    Abstract: An adhesive bandage is provided. The adhesive bandage compromises a strip having an upper surface and a lower surface; a wound-contacting pad disposed on the lower surface; at least one protective release tab removably disposed on the lower surface; wherein at least a portion of the upper surface is manufactured to match a particular user's skin tone.
    Type: Application
    Filed: September 12, 2013
    Publication date: March 12, 2015
    Inventor: Odette Perreault
  • Patent number: 8969649
    Abstract: A device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device. In particular, the device is an integrated dressing for catheters comprising a pad and an adhesive dressing.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: March 3, 2015
    Assignee: Ethicon, Inc.
    Inventors: Rebecca Leibowitz, Sandra Gensini, Joseph Zavatsky
  • Patent number: 8906679
    Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: December 9, 2014
    Assignee: Taipei Veterans General Hospital
    Inventors: Shih-Hwa Chiou, Cherng-Kang Perng, Han-Tzo Lin, Yi-Ping Yang
  • Patent number: 8907153
    Abstract: The present invention is drawn to adhesive peel-forming formulations for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a peel-forming agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent, wherein the non-volatile solvent system has a solubility for the drug that is within a window of operable solubility for the drug such that the drug can be delivered at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified peelable layer after at least a portion of the volatile solvent system is evaporated.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: December 9, 2014
    Assignee: Nuvo Research Inc.
    Inventors: Jie Zhang, Kevin S. Warner, Michael A. Ashburn, Larry D. Rigby, Suyi Niu
  • Publication number: 20140303541
    Abstract: Medical devices, wound dressings, and methods of dressing wounds are described. Devices and methods using silicone and pharmaceutically active agents are described. Devices including covers and bases are described.
    Type: Application
    Filed: November 17, 2011
    Publication date: October 9, 2014
    Inventor: David J. Vachon
  • Patent number: 8851284
    Abstract: A bandage strip includes a plurality of flat adhesive bandage packages of conventional configuration, having sealed therein an adhesive bandage with a pad and an adhesive substrate for adhering to a patient and holding the pad in place on the patient's skin. The packages are adhered to an elongated substrate in end-to-end, spaced relation to form a flat, elongated bandage strip, with perforations in the substrate between the packages. A user can dispense a length of substrate, sever it at the perforations, and remove the bandage from the substrate for use in the conventional manner. A bandage dispensing device is attachable to the wrist of a user for convenient dispensing of bandages from a strip of individually packaged bandages.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: October 7, 2014
    Assignee: Thuban, Inc.
    Inventor: Rana J. Arefieg
  • Patent number: 8846076
    Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: September 30, 2014
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Publication number: 20140288478
    Abstract: A new bandage package having a loosely packaged carrier material with a plurality of bandages attached. The package allows the bandages to be kept sterile when opening the package by allowing the carrier to fall freely to a sterile surface without the user touching the carrier.
    Type: Application
    Filed: June 6, 2014
    Publication date: September 25, 2014
    Inventors: Jerry Holubec, Robert McCoskey
  • Patent number: 8822751
    Abstract: The adhesive bandage consists of a support with one surface having pressure sensitive adhesive and a wound covering pad placed centrally on it, which are covered by two protective detachable tear away tabs. The tear away tab consists of a single layer over the adhesive surface of the support and becomes two layered over the pad region. The two layers are fused at the zone of fusion near the margin of the pad, but are otherwise free from each other. The layer close to the pad, called inner barrier layer, completely covers the pad area. The outer layer, also called grasping layer, partially covers the barrier layer and the pad, and is folded upon itself to give sufficient length. When the outer layer is grasped to pull apart the releasable tear away tabs the inner barrier layer prevents contact of the finger to the pad. As one pulls apart the tear away tabs the barrier layers unfold and prevent contact of the fingers with the wound and wound exudates, preventing cross contamination.
    Type: Grant
    Filed: July 4, 2008
    Date of Patent: September 2, 2014
    Inventor: Kalpesh Jayantkumar Gajiwala
  • Patent number: 8809615
    Abstract: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: August 19, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kiyomi Tsuruda, Shinji Yamasoto, Kouki Shoho, Masaru Nakanishi
  • Patent number: 8784876
    Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: July 22, 2014
    Assignee: Z-Medica, LLC
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Patent number: 8764792
    Abstract: An elongated flexible base strip is constructed with a bottom surface coated with an adhesive material. The base strip is constructed with bridging links which are spaced along the inner edge of the base strip and extend outward therefrom. The base strip, is cut to a first length and aligned with the wound with the bridging links extending over the wound. A matching portion of base strip is cut to a second length and aligned with the wound with the bridging links opposing. The opposing links are drawn together to close the wound. Adhesive on the links holds the links to the opposite base strip.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: July 1, 2014
    Inventor: Leslie Philipp Weiser
  • Patent number: 8742196
    Abstract: The invention provides an adhesive support article for supporting a body part of a user. A single-sided stretchable adhesive tape blank is precut into a sheet having a central anchoring portion and a plurality of outwardly extending fingers. The sheet is marked with visual indicators to guide the user of the support article for applying the central anchoring portion onto a first exterior surface of the body part and for stretching the fingers before adhering them at a predetermined distance away from the central anchoring portion. The adhesive support article can also be provided in a support system with at least one corresponding body landmark article, providing further guidance for applying the support article to the desired body part.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: June 3, 2014
    Inventors: Ray Arbesman, Kevin Jardine
  • Patent number: 8697932
    Abstract: Switchable adhesives comprising a mixture, in proportions by weight, of 20% to 98% of an adhesive, 2% to 80% of curable molecules and 0.05% to 10% of photoinitiator. Preferably, the adhesive and curable molecules are mutually soluble when dry or the curable molecules and adhesive may be uniformly dispersed in each other. Preferably the amount of adhesive in the mixture is in the range 40% to 98% by weight, more preferably 60% to 95% by weight, even more preferably 70% to 85% by weight. Preferably the proportion of curable molecules in the mixture ranges from 2% to 60% by weight, more preferably 5% to 40% by weight, even more preferably 15% to 30% by weight. Preferably, the photoinitiator is present in the mixture in the proportions 0.5% to 5% by weight, more preferably 1% to 3% by weight. Such switchable adhesives are useful in medical dressings and other removable sheet products, and may be simply prepared by stirring the adhesive, the curable molecules and the photoinitiator together at room temperature.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: April 15, 2014
    Assignee: Lumina Adhesives AB
    Inventor: Mats Tunius
  • Patent number: 8692050
    Abstract: A medicated patch is provided which is covered with a liner that enables one to remove the liner unconsciously and readily without losing the initial stickiness of the medicated patch. The external medicated patch includes a backing, an aqueous adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that is larger in size than the surface of the drug-containing matrix to which the liner is attached. The liner larger in size than the surface of the drug-containing matrix to which the liner is attached includes an unattached area that extends from the surface of the drug-containing matrix, or an unattached slack portion that projects upward from the surface of the drug-containing matrix at a position on the surface of the drug-containing matrix.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: April 8, 2014
    Assignee: Teikoku Seiyaku Co., Ltd.
    Inventor: Masanori Uematsu
  • Patent number: 8691355
    Abstract: Disclosed is a film dressing comprising a film dressing body. The film dressing body (1) comprises a film (2) and a pressure-sensitive adhesive layer (3) provided on one side of the film (2). The film dressing further comprises a release liner (4) covering the pressure-sensitive adhesive layer (3) on its adhesive face, and a carrier (5) covering the backside of the film (2). A carrier division part (5d) is provided to divide the carrier (5) into a carrier first part (51) and a carrier second part (52). A flap layer (7) is stacked so as to cover the carrier division part (5d). A flap layer division part (7d) is provided in the flap layer (7) to divide the flap layer (7) into a flap layer first part (71) and a flap layer second part (72) which are partially joined respectively on the carrier first pat (51) and the carrier second part (52). Preferably, division parts (4d1, 4d2) are provided in the release liner (4).
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: April 8, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Yoshio Funakoshi, Seishi Suzuki
  • Publication number: 20140012102
    Abstract: Wearable patches comprising multiple separable adhesive layers. One or more of the layers can comprise electronics, mechanical components, gauze, medicine and/or other types of hardware suitable for the intended use of the patch. In use, a first layer of the patch is adhered to a user. When it is time to change layers, the patch is removed from the user, the first layer is removed from the patch to expose a second adhesive layer, and the second layer is applied to the user. The process may be repeated until the remaining layers of the patch have been used.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 9, 2014
    Applicant: ZANSORS LLC
    Inventors: RANJIT DAS, MARK TRAVAGLINI
  • Publication number: 20130289465
    Abstract: An adhesive product is disclosed, in which a portion of the adhesive product may be removable. The adhesive product may be an adhesive bandage. The adhesive bandage may comprise removable tabs. The removable tabs may allow a user to handle the adhesive bandage without contaminating the portion of the adhesive bandage that will be applied to a wound. The removable tabs may be non-adhesive, allowing a user to apply the adhesive bandage without the adhesive bandage adhering to the user's fingers. The removable tabs may be separated from the adhesive bandage once the adhesive bandage has been secured in place.
    Type: Application
    Filed: April 24, 2013
    Publication date: October 31, 2013
    Inventor: James Hohnbaum
  • Patent number: 8563800
    Abstract: A sacral wound dressing having a bottom end with three substantially V-shaped projections. In use, a protective layer of the wound dressing is removed to expose an adhesive layer and an absorbent layer, the wound dressing is folded over on itself substantially along a central axis, a medial V-shaped projection is inserted into a superior portion of the gluteal cleft of the person to adhere the medial projection to the skin within the gluteal cleft, two lateral V-shaped projections are then pushed against a superior portion of the buttocks of the person to adhere the lateral projections to the skin, and the opposing lateral ends and the top end of the wound dressing are then pushed against the skin of the person until the wound dressing is properly adhered to the sacrococcygeal region over the sacral wound.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: October 22, 2013
    Inventor: Patricia A. Smith
  • Patent number: 8561796
    Abstract: Disclosed herein is a package material for adhesive bandage which is used for packaging therein an adhesive bandage including a surface base having one surface, an adhesive layer provided on the one surface of the surface base and a releasing sheet attached to the adhesive layer so as to cover it. The package material comprises a first sheet having a first sheet base and a first cold seal layer provided on the first sheet base, and a second sheet having a second sheet base and a second cold seal layer provided on the second sheet base. The first cold seal layer faces the surface base of the adhesive bandage and the second cold seal layer faces the releasing sheet of the adhesive bandage when the adhesive bandage is packaged in the package material.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: October 22, 2013
    Assignee: Lintec Corporation
    Inventors: Tomio Hatanaka, Yumi Sumitani
  • Patent number: 8530022
    Abstract: An article (1) of a medical and technical nature intended to be affixed to skin, or a component for affixing a medical article or part thereof to skin, which article or component comprises a layer of carrier material (2) that has a layer (3) of a soft skin-friendly adhesive on one side, and a protection layer (4) that protects the adhesive layer before use of the article or component and is affixed to the adhesive layer in such a way that it is releasable. According to the invention, the protection layer (4) is provided with a pattern of projections (6) on the side facing towards the adhesive layer (3) and a reinforcing layer (5) is arranged on the layer of carrier material (2), on the opposite side to the side that has the layer of soft skin-friendly adhesive, in such a way that it can be removed.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: September 10, 2013
    Assignee: Molnlycke Health Care AB
    Inventors: Tomas Fabo, Anna Svensby, Ulf Johannison, Dennis Hansson
  • Patent number: 8522976
    Abstract: Systems and dispensers, including methods of using the same, for dispensing bandages comprising: a dispenser body comprising a receiving surface with a first retention element and a hinged flap with a second retention element, wherein the hinged flap is foldable to overlay at least a portion of the receiving surface; and at least one bandage pack disposed on the receiving surface, wherein the bandage pack comprises at least one individually wrapped bandage; provided that when the hinged flap is folded to overlay the receiving surface, a first retention element reversibly interlocks with a second retention element thus securely retaining the at least one bandage pack.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: September 3, 2013
    Assignee: Tender Corporation
    Inventor: Michael Holstein
  • Patent number: 8497407
    Abstract: The present invention relates to a film dressing comprising a thin plastic film (2) coated with an adhesive (3). In accordance with the invention, the adhesive (3) has a softness of 10-22 mm, and the adhesive coating has a weight per unit area of 50 g/m2 or more.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: July 30, 2013
    Assignee: Molnlycke Health Care AB
    Inventors: Tomas Fabo, Bengt Söderström, Anna Svensby
  • Patent number: 8486426
    Abstract: The present invention comprises methods and compositions for the treatment of pathological conditions of the dermis and dermal structures of animals and humans. In particular, the present invention comprises the use of topical delivery vehicles, including hydrogels, which incorporate active agents such as organic acids, for the treatment of dermal conditions.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: July 16, 2013
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Joseph C. Maley, Bruce L. Gibbins
  • Patent number: 8470597
    Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: June 25, 2013
    Assignee: Taipei Veterans General Hospital
    Inventors: Shih-Hwa Chiou, Cherng-Kang Perng, Han-Tzo Lin, Yi-Ping Yang
  • Patent number: 8460699
    Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: June 11, 2013
    Assignee: Z-Medica, LLC
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Publication number: 20130102947
    Abstract: The present invention relates to a wound dressing which comprises a hydrocolloid adhesive mass comprising: a hydrophobic elastomer matrix comprising polystyrene-olefin-styrene) block copolymers, particles of hydrocolloid(s) dispersed in said elastomer matrix, at least two hydrogenated-hydrocarbon tackifying resins, the difference between the softening temperatures of a first hydrogenated-hydrocarbon tackifying resin and of a second hydrogenated-hydrocarbon tackifying resin comprised in the hydrocolloid adhesive mass being at least 10° C. and at most 40° C.
    Type: Application
    Filed: April 27, 2011
    Publication date: April 25, 2013
    Applicant: LABORATOIRES URGO
    Inventor: Stephane Auguste
  • Patent number: 8426668
    Abstract: A dressing product includes a cover sheet, a carrier system, and a dressing sheet. The carrier system includes a periphery that is attached to the cover sheet and a lower portion that extends from the periphery to a protruding portion. The protruding portion of the carrier system is spaced apart from the cover sheet by the lower portion of the carrier system to define a cavity between the cover sheet and the carrier system. The dressing sheet includes a backing layer and an adhesive attached to the backing layer. The dressing sheet is disposed in the cavity and is contained between sidewalls that are defined by the lower portion of the carrier system.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: April 23, 2013
    Assignee: Colopast A/S
    Inventors: Lotte Madsen, Anne-Marie Søbye Rapp, Grazyna Hansen, Bjoern Christiansen, Jan Marcussen, Troels Schoenfeldt, Morten Thomsen
  • Patent number: 8383148
    Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: February 26, 2013
    Assignee: Z-Medica, LLC
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Publication number: 20130012859
    Abstract: Disclosed herein are a packaged medical adhesive composite and a method of delivering the composite. The medical adhesive composite comprises a single tab as a release liner that partially covers the adhesive side of the composite. The tab can be used to apply the composite with only a single hand, even without compromising the sterility of the absorbent pad used to cover a wound. The medical adhesive composite can comprise an especially thin supple backing and be delivered over a wound with little or no wrinkling of the backing. The medical adhesive composite can be delivered such that the composite overlaps with itself when applied, for example, to a finger.
    Type: Application
    Filed: December 8, 2010
    Publication date: January 10, 2013
    Inventor: Amy J. Krohn
  • Patent number: 8343537
    Abstract: A hemostatic device for promoting the dotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: January 1, 2013
    Assignee: Z-Medica, LLC
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Patent number: 8344201
    Abstract: A dressing product includes a thin film dressing sheet, one first surface of which is coated with an adhesive, such as a pressure sensitive hydrocolloid adhesive, which is applicable to an anatomical surface of a human. A carrier system, which provides a support for the dressing sheet, defines a gripping section for handling of the carrier system. The carrier system may include one or more foil members and supporting sheets for facilitating application and for providing a non-touch application system, i.e., a system which may be handled by an operator without the operator touching the dressing sheet or at least the adhesive surface. A protective sheet having an opening for application of a pharmaceutical product to the adhesive prior to application of the dressing sheet is disclosed.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: January 1, 2013
    Assignee: Coloplast A/S
    Inventors: Lotte Madsen, Anne-Marie Søbye Rapp, Grazyna Hansen, Bjoern Christiansen, Jan Marcussen, Troels Schoenfeldt, Morten Thomsen
  • Publication number: 20120277645
    Abstract: Provided is a stretch adhesive bandage having an adhesive layer 2 and a release liner 3 laminated in this order on one surface of a bandlike fabric base 1. The adhesive bandage after peeling off the release liner 3 is stretchable at least in the longitudinal direction (in the longitudinal direction and the in the width direction in the first embodiment and only in the longitudinal direction in the second embodiment). The release liner 3 has perforation lines K (K1, K2) in the longitudinal direction and in the width direction in the first embodiment, and at least perforation line K in the width direction is formed in the second embodiment, and any perforation line is broken to be a dividing line by stretching the adhesive bandage in a direction perpendicular to the travelling direction of the perforation line.
    Type: Application
    Filed: April 18, 2012
    Publication date: November 1, 2012
    Applicant: NITTO DENKO CORPORATION
    Inventors: Noriyuki KIKUTA, Atsushi HAMADA, Takeo MATSUMURA, Shigeki TAKAKI
  • Patent number: 8272386
    Abstract: A surgical wound closure device comprising multiple layers joined at only one edge of each layer in a book-like arrangement and having opposite unjoined edges, including a substrate having a proximal surface and a distal surface; a drape having a proximal surface and a distal surface, and being disposed proximally to said substrate; and an adhesive layer having a proximal surface and a distal surface; said drape being disposed releasably adherently to said distal surface of said adhesive layer. Also provided is a surgical procedure employing a surgical wound closure device.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: September 25, 2012
    Assignee: Ethicon, Inc.
    Inventors: Robert A. Rousseau, An-Min Jason Sung
  • Patent number: 8257732
    Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: September 4, 2012
    Assignee: Z-Medica Corporation
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Publication number: 20120184891
    Abstract: A method is provided to attach a grip tab along an edge of a carrier layer of a film dressing web, which includes a film layer coated with adhesive on a first side and a carrier layer releasably attached to the film layer on an opposed second side. The method includes choosing a material for the carrier layer that is heat welding incompatible with the film layer, feeding the web in a machine direction, applying a first strip of a material that is heat welding compatible with the carrier layer along part of an edge portion of the web extending parallel to the machine direction, and affixing the first strip to the carrier layer while simultaneously cutting away an outermost part of the web with the first strip applied thereto by passing the web through an ultrasonic welding device.
    Type: Application
    Filed: August 19, 2010
    Publication date: July 19, 2012
    Applicant: MOLNLYCKE HEALTH CARE AB
    Inventor: Ulf Johannison
  • Patent number: 8202532
    Abstract: Disclosed are device for promoting the clotting of blood comprising a clay material and a release agent. In some embodiments, the clay material is disposed within a substrate and the release agent is disposed within a mesh. The release agent can be configured to make direct contact with a bleeding wound when the device is in particle form and the clay material can promote hemostasis.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: June 19, 2012
    Assignee: Z-Medica Corporation
    Inventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
  • Patent number: 8197803
    Abstract: Liquid hemostatic coating materials comprise a cyanoacrylate monomer and a solvent system comprising a volatile, non-reactive liquid that is non-stinging and non-irritating to a user. The material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: June 12, 2012
    Assignee: Rochal Industries, LLP
    Inventors: Ann Beal Salamone, Joseph C. Salamone
  • Patent number: 8168851
    Abstract: An adhesive skin patch sheet comprises a support, a pressure-sensitive adhesive layer and a release sheet laminated in that order, the release sheet is divided by a cut line into a small first release sheet and a large second release sheet, the cut line is formed so as to be convex only from the second release sheet toward the first release sheet.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: May 1, 2012
    Assignee: Lintec Corporation
    Inventors: Kaname Nakahara, Atsuko Kameshima
  • Patent number: 8155738
    Abstract: Device structure 100 for iontophoresis provides electrode 101 and electrically conductive layer 102. Electrically conductive layer 102 contains active ingredient D and basic water swelling methacrylate copolymer P1 and/or acidic water swelling methacrylate copolymer P2. Electrode 101 and electrically conductive layer 102 are placed into a hollow of backing 103 and electrode terminal 104 is connected to electrode 101 through backing 103. Adhesive layer 105 is set around backing 103, and liner 106 to be removed when using the device, is placed so as to cover the hollow of backing 103.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: April 10, 2012
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Hirotoshi Adachi, Noriyuki Kuzumaki, Tetsuya Arimoto, Naruhito Higo