Abstract: A system is disclosed for repairing and reconstructing an injured anterior cruciate ligament (ACL). This system may be used irrespective of the type of patient or the ACL graft selected. Means for performing single or multiple bundle reconstruction, primary ACL repair and physeal-sparing ACL reconstruction are disclosed. A guide for inside-out creation of a femoral tunnel independent of the tibial tunnel is also disclosed, as well as a series of implant options for tibial and femoral fixation of any bone-soft-tissue composite or soft-tissue-only graft.

Abstract: A surgical cutting instrument including a first tubular member, a second tubular member, a sleeve member, a third tubular member, and an orientation member. A distal section of the first tubular member includes a cutting tip. The distal region of the second tubular member forms a cutting window. The first elongated member is co-axially disposed within the second tubular member such that the cutting tip is selectively exposed at the cutting window. The first and second tubular members are co-axially disposed within the sleeve member. The third tubular member is co-axially disposed around the intermediate section of the first tubular member, the intermediate region of the second tubular member and the sleeve member. The orientation member is rotatable to transmit a rotational force applied to the orientation member to selectively rotate the second and third tubular members relative to the sleeve to effectuate spatial rotation of the cutting window.

Abstract: An apparatus comprises a body, an ultrasonic transducer assembly, a shaft assembly, and a coupling assembly. The shaft assembly comprises an acoustic waveguide that is operable to selectively couple with the ultrasonic transducer assembly. The coupling assembly is operable to selectively transition between a first mode and a second mode. The acoustic waveguide is configured to rotate with the transducer assembly relative to the body when the coupling assembly is in the first mode. The acoustic waveguide is configured to rotate relative to the transducer assembly and relative to the body when the coupling assembly is in the second mode. The coupling assembly is further configured to prevent the transducer assembly from rotating relative to the body when the coupling assembly is in the second mode. The shaft assembly and the end effector are also together configured to transition between an operational mode and a cleaning mode.

Abstract: A retinal treatment system for delivering therapeutic agents to a target location with a retina is disclosed herein. The retinal treatment system includes a console having a control system and a handheld device coupled to the control system. The handheld device includes an inner tube disposed within an outer tube and being axially moveable within the outer tube. The inner tube has a perforating tip that is configured to perforate an inner limiting membrane of the retina. The handheld device further includes a chamber coupled to a proximal end of the inner tube that is configured to receive a fluid containing therapeutic agents injectable from the perforating tip. The control system of the retinal treatment system permits a user to maintain a position of the handheld device relative to the retina and activate an injection of a portion of the fluid through the inner tube into the retina.

Abstract: The present disclosure provides a low-profile system and methods for delivering a microneedle array. The delivery system includes a housing that may be secured to and temporarily worn on a patient's skin. A carrier assembly coupled to a microneedle array is received in the housing proximate an applicator device. The carrier assembly is at least releasably secured to the housing and it is typically not attached or otherwise fixed to any portion of the applicator device.

Abstract: An apparatus comprises a body, a shaft assembly, and an end effector. The shaft assembly extends distally from the body. The end effector is located at a distal end of the shaft assembly. The end effector comprises an ultrasonic blade and a clamp arm. The ultrasonic blade is configured to vibrate at an ultrasonic frequency. The clamp arm comprises a clamp pad. The clamp arm is movable toward the ultrasonic blade to compress tissue between the clamp pad and the ultrasonic blade in two stages. During the first stage, the clamp arm is configured to compress tissue with only a distal portion of the clamp pad. During the second stage, the clamp arm is configured to compress tissue with the distal portion and a proximal portion of the clamp pad. Thus, the tissue compression begins at the distal portion and subsequently progresses toward the proximal portion.

Abstract: Tissue may be cut and extracted from an interior location in a patient's body using a probe or tool which both effects cutting and causes vaporization of a liquid or other fluid to propel the cut tissue through an extraction lumen of the cutting device. The cutting may be achieved using an electrosurgical electrode assembly, including a first electrode on a cutting member and a second electrode within a cutting probe or tool.

Abstract: Devices, systems, and methods for treatment of an eye alter aspiration flow from the eye in response to an occlusion of the aspiration conduit pathway. Where aspiration is drawn from the eye using a volumetric pump, the pump can be reversed so as to induce fluid reflux from the aspiration conduit pathway into the eye to help clear the occlusion. The pump may vary the reverse flow in response to sensed aspiration pressure or the like, and the reverse flow may be halted before the pressure within the aspiration conduit pathway adjacent the eye significantly exceeds the irrigation fluid pressure and/or the pressure within the eye. Reflux may alternatively be generated by modulating a vent valve disposed between an irrigation conduit pathway and the aspiration conduit pathway.

Abstract: A high-frequency surgical device for treating a tissue surface, device having an electrode device, in which a first electrode is formed on a working surface intended for contact with the tissue, and having a high-frequency generator, to the one pole of which the first electrode can be connected for operation. The surgical device is wherein a second electrode is formed on the working surface which electrode can be connected to the same pole, wherein a control device is connected to this and is designed initially to connect the first electrode and then to switch on the second electrode.

Abstract: A system for treating tissue includes a device including a first member and a second member arranged to move relative to the first member to treat tissue. The system also includes a processor configured to automatically control movement of the second member relative to the first member using position control methodology. A method of treating tissue includes providing a device having a first member and a second member arranged to move relative to the first member, moving the second member relative to the first member, and automatically controlling the movement of the second member using position control methodology.

Abstract: An ophthalmic surgical probe for treating an eye of a patient includes a body, a cutting element extending distally from the body (the cutting element having a sleeve member with a port at an end), an inner member disposed within the sleeve member (the inner member being movable axially with respect to the sleeve member to open and close the port), and an actuating element secured to the inner member (the actuating member configured for operation in both a resonant mode and a non-resonant mode).

Abstract: Various exemplary methods, systems, and devices for controlling a motor of a robotic surgical system are provided.

Abstract: Provided is a fragmentation tip, an intraocular surgery device, a method for suppressing an occurrence of cavitation, and a cataract surgery method, which can suppress the occurrence of cavitation. The fragmentation tip, which is attached to an intraocular surgery device configured to apply ultrasonic vibration, includes: a cylindrical support portion configured to be mounted on the intraocular surgery device; and a cylindrical tip body provided at a distal end of the support portion to be in communication with an internal space of the support portion, wherein the tip body has a cross sectional shape having a length in a first direction that is larger than a length in a second direction that is orthogonal to the first direction, and vibration is applied to the support portion so that the tip body rotates back and forth about an axis of the tip body that passes through its center in the first and second directions.

Abstract: Devices and methods are discussed directed to the use of a low profile laser ablation catheter for use in laser ablation removal of arterial plaque blockages to restore blood flow in the treatment of arteriovenous fistulas. Also discussed are devices and methods directed to packaging, long term storage and sterilization of liquid core ablation catheters.

Abstract: The present invention relates to a device for cutting and aspirating tissue from the human or animal body, in particular for use in vitrectomy, epiretinal membrane peeling, etc., with an outer tube (1), and with an inner tube (2) which is movable to and fro and concentrically in the outer tube (1) with slight play, wherein the outer tube (1) is closed at the free end and has, near the free end, at least one lateral opening (3) with at least one inner cutting edge (5), wherein the inner tube (2) is open at the free end and there has an outer cutting edge (4), and wherein the cutting edges cooperate in a cutting action during the movement of the inner tube (2) relative to the outer tube (1), advantageously characterized by a shaping measure in or on the outer tube (1) and/or in or on the inner tube (2), whereby the inner tube (2), at least in the area of the lateral opening (3), runs in the outer tube (1) with at least slight pretensioning.

Abstract: An ultrasound catheter has an elongate flexible catheter body having a lumen extending longitudinally therethrough, and an ultrasound transmission member extending longitudinally through the lumen of the catheter body. The ultrasound transmission member has a proximal end that is coupled to a separate ultrasound generating device, and a distal tip that is attached to the distal end of the ultrasound transmission member and which is located at the distal end of the catheter body. The ultrasound transmission member is directly attached to the catheter body and/or to a guidewire tube either directly or via an attachment device. The catheter has an additional radiopaque marker positioned on the distal end the catheter.

Abstract: A tissue-removing catheter includes a cutting element. A radially innermost portion of the leading radial wall of a raised element of the cutting element may be spaced a radial distance from the longitudinal axis that is less than 66% of the radius of the annular cutting edge. The cutting element may be extendable through the window during operation such that as the cutting element is being rotated about its longitudinal axis, less than an entire radial portion of the leading radial wall passes through the window. A plurality of abrading members may be formed on at least the central portion of the inner surface of the cutting element to abrade hardened tissue as the cutting element is rotating about its longitudinal axis. A radially outermost portion of the leading radial edge of the raised element may be spaced apart radially from an inner surface of the cutting element.

Abstract: Dendritic polypeptides useful for the delivery of therapeutic agents into cells are disclosed, together with their methods of preparation. These dendritic polypeptides serve as carriers of drugs, siRNA, aptamers and plasmid DNA in the treatment of various diseases, including cancer.

Abstract: Systems and methods for treating a patient's mucus hypersecretion condition are disclosed herein. Certain implementations may involve a method for reducing mucus secretion in an upper airway of a patient to treat at least one of post nasal drip or chronic cough. The method may include advancing a treatment delivery portion of an energy-based treatment device into a nostril of the patient. The treatment delivery portion may contact mucosal tissue of the upper airway without piercing the mucosal tissue. The treatment delivery portion may deliver treatment to at least one tissue selected from the group of the mucosal tissue and another tissue underlying the mucosal tissue to modify a property of the at least one tissue and thus treat at least one of post nasal drip or chronic cough in the patient.

Abstract: A combination of an irrigation sleeve 20 and a phacoemulsification needle 22. The irrigation sleeve 20 has a proximal end 32 and a distal end 30, the proximal end for attachment to a surgical handpiece. The phacoemulsification needle 22 has a proximal end 26, a distal end 24, and a lumen 38 spanning a length of the needle 22 from the proximal end 26 to the distal end 24. The needle proximal end 26 is for connection to the surgical handpiece, and the needle 22 has structure 44 proximate the needle distal end 24 for retaining the sleeve distal end 30 near the needle distal end 24.

Abstract: A method may include coupling a proximal end of a first cannula to a first manipulator of a surgical system, the first manipulator being configured to remotely actuate movement of the first cannula, wherein the first cannula comprises a rigid portion disposed between the proximal end and a distal end of the first cannula, the rigid portion having a curved longitudinal axis, and coupling a proximal end of a second cannula to a second manipulator of a surgical system, the second manipulator being configured to remotely actuate movement of the second cannula, wherein the second cannula comprises a rigid portion disposed between the proximal end and a distal end of the second cannula, the rigid portion having a curved longitudinal axis.

Abstract: To be able to use a generally available database of predetermined apparatus configurations and parameters in medical interventions, a device is disclosed for controlling and/or monitoring at least one apparatus during a medical intervention, said device including a least one control unit for controlling and/or monitoring the at least one apparatus and at least one display unit for displaying data, wherein: access is possible to data specific to the intervention, including at least data on the parameter values to be entered on the at least one apparatus during a predetermined intervention; in addition the parameter values are predetermined at least in part depending on the user, while the parameter values can be called up by a user for display by means of the display unit, and a confirming element is provided, through whose actuation the predetermined parameter values for the at least one apparatus are incorporated.

Abstract: An energy delivery probe for use in tissue ablation and method of use is presented. The energy delivery device has at least a first energy delivery member and a second energy delivery member that have handle members positioned along a longitudinal axis, each handle member having a proximal and distal end. The distal end of the first handle member is releasably coupled to the proximal end of the second handle member and a portion of each member is defined in a coaxially surrounding relationship to each other along the longitudinal axis. The method of using the probe involves identifying a tissue to be ablated, providing the energy delivery probe, inserting at least a portion of the energy delivery probe into the identified tissue, delivering electrical energy through the energy delivery probe to the identified tissue, and ablating the identified tissue such that at least a first ablation zone is formed.

Abstract: Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the tissue separating device includes a handle, an elongate sheath and a circular cutting blade that may extend from the distal end of the sheath upon actuating the handle. The elongate sheath, particularly its distal end, includes a non-uniform wall thickness having one or more thicker portions in the outer sheath, particularly the outer cam member, and/or one or more thicker portions in an inner member disposed radially inward of the blade.

Abstract: A method for ultrasonically treating tissue includes accessing a surgical site with an ultrasonic surgical instrument, dissecting tissue with a first portion of the blade, and sealing tissue with a second portion of the blade. The instrument includes a blade that defines a longitudinal axis. The blade is configured to oscillate along the longitudinal axis to ultrasonically treat tissue.

Abstract: Described is a processor comprising: a plurality of transistors operable to provide dynamically adjustable transistor size, the plurality of transistors coupled at one end to a first power supply and coupled at another end to a second power supply; a circuit coupled to the second power supply, the second power supply to provide power to the circuit; and a power control unit (PCU) to monitor the level of the first power supply, and to dynamically adjust the transistor size of the plurality of transistors so that the second power supply is adjusted to keep the circuit operational.

Abstract: A phacoemulsification irrigation sleeve having a body configured to operatively connect to a phacoemulsification needle. The body has proximal and distal ends and defines a passageway for liquid. A first irrigation port is formed in the body between its proximal and distal ends. The body is slit to define a first flap configured to swing away from the first irrigation port in response to pressure of fluid flowing in the passageway to thereby reduce resistance of fluid flow through the first irrigation port. The first flap, when swung away from the first irrigation port, is oriented to direct fluid flowing through the first irrigation port in a direction from the proximal end of the body toward the distal end of the body.

Abstract: An orthopaedic surgical instrument comprising an orthopaedic cutting block includes a metallic bearing insert configured to support a bone cutting tool and a body molded to the bearing insert. The bearing insert includes a plurality of chemically etched holes, and the body is molded to the bearing insert such that each of the plurality of chemically etched holes is at least partially filled by a portion of the body. The body of the orthopaedic cutting block may include a bone-facing surface adapted to contact a portion of a patient's bone, and the bearing insert may be positioned to allow a surgeon to perform a cut on the patient's bone using the bearing insert for support. A method of manufacturing an orthopaedic surgical instrument is also disclosed.

Abstract: Methods and surgical tools for treating back pain use a spinal facet debridement tool with cautery and denuding action and minimally invasive protocol that uses a low rotation speed and a power source configured with a cautery head with scraping elements that can denude and cauterize soft tissue associated with a synovial capsule of the spinal facet joint.

Abstract: Fluid transfer systems are disclosed that can be configured to transfer precise amounts of fluid from a source container to a target container. The fluid transfer system can have multiple fluid transfer stations for transferring fluids into multiple target containers or for combining different types of fluids into a single target container to form a mixture. The fluid transfer system can include a pump and a destination sensor, such as a weight sensor. The fluid transfer system can be configured to flush remaining fluid out of a connector to reduce waste, using air or a flushing fluid.

Abstract: A surgical apparatus and method according to which a cable assembly is connected to a handpiece and includes a sensing element, and a member adapted to move relative to the sensing element to control the operation of a motor in the handpiece.

Abstract: A microneedle injection and infusion apparatus, and a method of using same. The apparatus (100) can include a housing (102), a microneedle array holder (106) for holding a microneedle array (107), and a shuttle (125) that holds a cartridge (e.g., that contains an active agent). The microneedle array holder can be movable between a retracted position and an extended position. The shuttle can be movable between a first position in which the cartridge is not in fluid communication with a fluid path and a second position in which the cartridge is in fluid communication with the fluid path. The apparatus can further include an actuator (104) movable between a first position and a second position. The method can include moving the actuator to its second position to allow the shuttle to move toward its second position, wherein movement of the shuttle toward its second position allows the microneedle array holder to move to its extended position.

Abstract: Embodiments of the present invention are directed to ablation catheter systems configured, for example, to ablate tissue adjacent an ostium of the pulmonary vein in a left atria of a heart. In one embodiment, an ablation catheter system includes a handle and a catheter coupled to the handle defining a lumen extending through a length of the catheter, the catheter including a distal end thereof. The ablation catheter system may also include an electrode coupled to the handle with lines extending through the lumen of the catheter, the electrode being configured to be constrained adjacent the distal end of the catheter and configured to be deployed from the distal end of the catheter to an expanded configuration.

Abstract: A method and apparatus for identifying a member used in a navigation system. The navigation system can determine the identification of an instrument via an input. The input can be substantially automatic when an instrument is introduced into the navigation system field or assembly.

Abstract: A water jet instrument may be used for manually performing eye surgery such as, cataract, or perform micro-surgery (remove cartilage), or any emulsification technique. The water jet instrument may be manually controlled or controlled by a system with a robotic control. The water jet apparatus defines a jet cutting area that is based at least in part on a flow rate meter and a feedback loop.

Abstract: An instrument test arrangement is specified, which is preferably equipped for medical instruments for argon plasma coagulation. The instrument test arrangement comprises an electrode arrangement, comprising at least one test electrode. In a preferred embodiment, a test electrode is thereby connected to two neutral conductors of a neutral conductor cable or device, wherein the neutral conductors are insulated from one another, and wherein the first coupling impedance between the test electrode and the first neutral conductor and the second coupling impedance between the test electrode and the second neutral conductor are equal or at most slightly different, so that a split circuit, which is assigned to a neutral electrode arrangement, does not trigger due to the strike of a test spark or arc.

Abstract: A device for performing a surgical procedure includes an elongated shaft extending between a proximal end and a distal end. The shaft includes an outer surface and an inner surface. An expandable member is disposed at the distal end of the shaft. The expandable member is configured to receive inflation material. At least one electrode is disposed with the inflatable member. Methods of use are disclosed.

Abstract: A blade assembly comprising: a tip including two or more tubes, wherein the two or more tubes include at least: an outer tube and an inner tube; and a mechanical enclosure including: a locking spline having a longitudinal axis; and a slide lock; wherein the slide lock slides along the longitudinal axis of the locking spline and over the locking spline forming a locked state so that rotational movement of the locking spline, around the longitudinal axis of the locking spline, is prevented; and wherein the outer tube is coupled to the locking spline so that rotational movement of the outer tube, around the longitudinal axis of the locking spline, is prevented during the locked state.

Abstract: In various embodiments, a cannula device includes an irrigation handpiece portion (with a first aspiration tip for aspiration and an irrigation fluid outlet for irrigation) and an aspiration handpiece portion (configured to aspirate fluid into a second aspiration tip that extends from a distal end of the aspiration handpiece portion). The cannula device is transformable between: (a) a coaxial mode in which the aspiration handpiece portion is coupled to the irrigation handpiece portion such that fluid is aspirated through the first aspiration tip and then the second aspiration tip in series and irrigation fluid is provided through the irrigation fluid outlet, and (b) a bimanual mode in which the aspiration handpiece portion is separated from the irrigation handpiece portion to provide aspiration through the second aspiration tip while the irrigation handpiece portion continues to provide irrigation fluid through the irrigation fluid outlet.

Abstract: The present disclosure relates to bite plates for use with various orthodontic remodeling devices. A bite plate that releases fluoride during use, thus encouraging remineralization on enamel is described. Additionally, bite plates with a colorant or color-changing matrix that serve as indicators for fluoride concentration are also described.

Abstract: Provided is a tip for phacoemulsification superior in ability to efficiently and smoothly crush and suck a crystalline lens. A tip (1) of the present invention includes: a shaft (2) having first and second ends (21, 22); a distal part (3) arranged at the first end (21) of the shaft (2) and having an opening (4); and a suction passage (5) extending from the opening (4) of the distal part (3) to the second end (22) of the shaft (2). The suction passage (5) is narrowed in a staircase shape (51) or/and a helical shape (53) from the opening (4) toward the shaft (2). It is preferable that one or a plurality of guide grooves (52) leading from the opening (4) toward the shaft (2) are further formed in an inner wall of the suction passage (5).

Abstract: An intravascular emboli capture and retrieval system for intravascular embolism protection and embolism removal or maceration. Guidewire mounted proximally and distally located multiple opening filters are deployed within the vasculature and used to part, divide and macerate embolic debris and to capture such embolic debris within the confines thereof. A deployable flexible preformed memory shaped capture sleeve is alternatively used to collapse one or more filters and embolic debris therein for subsequent proximal withdrawal from the vasculature.

Abstract: A dual blade device and method useable for performing an ab interno procedure within a human eye to remove a strip of trabecular meshwork tissue.

Abstract: A bendable medical device such as for removing tissue from a subject is provided with a distal housing, an outer support tube, an inner drive tube, a coupler and a commutator portion. The coupler and commutator portion serve to axially constrain a distal end of the inner drive tube during bending, and to supply fluid for lubricating, cooling and irrigating the distal end of the device.

Abstract: A device insertable in the ear canal for substance delivery to and/or extraction from the tympanic cavity is described that includes a stationary body having a distal surface, a proximal surface; a movable body having a distal surface and a proximal surface, disposed within the stationary body and free to move relative to the stationary body in response to a pressure difference created in the ear canal; and at least one piercing element having a distal end and a proximal end, disposed in the movable body.

Abstract: Systems and methods for treating a patient's mucus hypersecretion condition are disclosed herein. Certain implementations may involve a method for reducing mucus secretion in an upper airway of a patient to treat at least one of post nasal drip or chronic cough. The method may include advancing a treatment delivery portion of an energy-based treatment device into a nostril of the patient. The treatment delivery portion may contact mucosal tissue of the upper airway without piercing the mucosal tissue. The treatment delivery portion may deliver treatment to at least one tissue selected from the group of the mucosal tissue and another tissue underlying the mucosal tissue to modify a property of the at least one tissue and thus treat at least one of post nasal drip or chronic cough in the patient.

Abstract: A clot retrieval device, for example to be used in a thrombectomy, is provided including a catheter, an elongated member, and a knitted basket with a proximal end coupled to the catheter and a distal end coupled to the elongated member. The elongated member is movable between an expanded position and a compressed position relative to the catheter and is configured so that the knitted basket expands radially and compresses as the elongated member is moved to the compressed position. The knitted basket is comprised of a plurality of wires coupled together by a plurality of windings. Each winding comprises one of the plurality of the wires twisted about another of the plurality of wires.

Abstract: A treatment assembly includes: a probe which includes a treatment section at a distal end portion thereof; an inner tube which includes a distal end and into which the probe is inserted in a state that the treatment section of the probe protrudes toward a distal end side with respect to the distal end; an opening which is provided in a side surface of the inner tube and which allows an inner side of the inner tube to communicate with an outer side of the inner tube; a support section which is arranged on the inner side of the inner tube from the outer side of the inner tube through the opening and which is configured to support the probe with respect to the inner tube; and an outer tube which covers the outer side of the inner tube and which is configured to fix the support section.

Abstract: In one embodiment, a surgical instrument comprises an articulable waveguide. The articulable waveguide may be configured to transmit ultrasonic energy therealong. The articulable waveguide comprises a proximal drive section, an end effector and a first flexible. The proximal drive section is configured to couple to an ultrasonic transducer. The end effector is located at a distal portion of the articulable waveguide. The first flexible section comprises a flex bias and be positioned between the proximal drive section and the end effector. The surgical instrument further comprises a first tine extending longitudinally relative to the articulable waveguide.

Abstract: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.