Method Patents (Class 604/28)
  • Patent number: 11369725
    Abstract: A deaerating device set allows a priming circuit to be deaerated fully automatically using a deaerating unit and a priming control unit, a priming liquid container and preferably a priming pump or a priming compressor. A blood pump is operated in a pulsatile manner during the pumping of a priming fluid.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: June 28, 2022
    Assignee: Xenios AG
    Inventors: Sven Filipon, Ozan Wagner
  • Patent number: 11357959
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct, such as the thoracic duct or the lymphatic duct, for example, the right lymphatic duct. A catheter system can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter system includes first and second selectively deployable restriction members each configured to be activated to at least partially occlude the vein within which the catheter is implanted and to thus restrict fluid within a portion of the vein. The catheter system includes an impeller configured to be driven by a motor to induce a low pressure zone between the restriction members by causing blood to be pumped through the catheter when the restriction members occlude the vein.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: June 14, 2022
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Sagi Raz, Shani Chen, Or Inbar
  • Patent number: 11351350
    Abstract: An apparatus is provided for connecting and disconnecting a tubular fitting connector to a fluid conduit. A cradle assembly accommodates the fluid conduit, and includes a body having a first port and a second port. The first and second ports are disposed at opposite ends of the body, and each port is configured for receiving an end cap of the tubular fitting to fasten or unfasten the end cap for replacement. A connector holder is disposed between the first and second ports, and is configured for accommodating insertion of the connector. A holder assembly is provided for accommodating insertion of the tubular fitting. The cradle assembly is reciprocable relative to the holder assembly for transitioning the cradle assembly between a first position, a second position, and a third position.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: June 7, 2022
    Assignee: PERIPAL AG
    Inventors: Stephan Fox, Mirko Meboldt, Sandra Neumann
  • Patent number: 11324932
    Abstract: The invention relates to a device for transanally introducing an infusion into the rectum or colon of a patient, said device comprising a catheter with a catheter shaft wherein, to ensure the most practicable catheter insertion possible, the catheter shaft is equipped in the proximal, preanal region with gripping depressions to accommodate the fingers gripping the catheter during insertion.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: May 10, 2022
    Assignee: Advanced Medical Balloons GmbH
    Inventor: Fred Göbel
  • Patent number: 11285306
    Abstract: A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: March 29, 2022
    Assignee: Morningside Venture Investments Limited
    Inventors: Andrew L. Johnston, Michael P. Schaller, Bryce Peterson, Kevin Gelston
  • Patent number: 11273292
    Abstract: System and components for inducing pleurodesis or other sclerosis or desired adhesion conditions to treat a patient, while minimizing likelihood of tissue damage from direct application of sclerosis-enhancing materials. A tube device is provided that is configured to elute sclerosis-enhancing material and/or other medicaments including autologous or otherwise patient compatible blood and/or blood component(s) via an assembly including fenestrated drainage tube which may be a multi-lumen assembly allowing simultaneous infusion/elution and drainage. The assembly of tube device with outer (typically drainage) tube may include one or more features configured to enhance delivery of medicament and/or drainage through the same assembly.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: March 15, 2022
    Assignee: Carefusion 2200, Inc.
    Inventors: Elise DeVries, John Krueger, Shayna Massi, John Ray, Palak Doshi
  • Patent number: 11273245
    Abstract: A system for performing a dialysis treatment includes a dialysis fluid machine; a disposable dialysis fluid carrying member operable with the dialysis fluid machine; and a venting filter provided by the disposable member, the venting filter positioned and arranged to be coupled along with the disposable member to the dialysis fluid machine to perform the dialysis treatment and to vent air from the disposable member.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: March 15, 2022
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Robert W. Childers, Richard Avoy, John Booras, Joseph H. Bowman, Paul Grippo, Andrew D. Hopping, David Howard, Jeffrey W. Jerrell, Benjamin Kellam, Brian Lauman, Sherwin Shang, David Vescovi, Tahua Yang, Alex Yu
  • Patent number: 11246987
    Abstract: A medicament delivery device (100) for a delivery of a medicament from a container (12) through a cannula (16). The device comprises a chassis (300), a carriage (200), and an insertion spring (70) for biasing the carriage (200) for movement in an insertion direction with respect to the chassis (300) from a starting position in which the cannula (16) is shrouded to an insertion position in which the cannula (16) is extended. A drive mechanism (400) is provided for driving a stopper (22) of the container (12) to expel the medicament. The drive mechanism (400) is carriage by the carriage (200) and comprises a movable drive member (404), a drive means (40) for applying a driving force to the drive member (404), and a force transmission means (406) for transmitting the driving force to the stopper (22). The drive means (40) is arranged around or alongside at least part of the force transmission means (406).
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: February 15, 2022
    Assignee: Owen Mumford Limited
    Inventors: Toby Cowe, Jake Mallon
  • Patent number: 11207515
    Abstract: A device is provided for shielding a fluid access port structure that is located along tubing that is part of an intravenous (IV) medication delivery system and is configured to permit injection of a fluid into the tubing. The device includes a body having a hollow interior and a first opening formed therein for receiving the fluid access port structure such that a side wall of the body surrounds and extends above the fluid access port structure. The body also includes a second opening through which a fluid delivery member can be inserted to allow mating between the fluid delivery member and the fluid access port structure for delivering the fluid into the tubing.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: December 28, 2021
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventor: David B. Wax
  • Patent number: 11167078
    Abstract: The present invention relates to an apparatus for flow tempering medical irrigation fluids and to a method carried out with the aid of this apparatus.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: November 9, 2021
    Assignee: W.O.M. WORLD OF MEDICINE GMBH
    Inventors: Andreas Lutz, Karl-Heinz Guenter Schoenborn
  • Patent number: 11090420
    Abstract: A method and device for performing extracorporeal blood treatment utilizes a first concentrate connection configured to feed a first concentrate into the device as a basis for generating a dialysate, and a second concentrate connection configured to feed a second concentrate into the device as a basis for generating a dialysate. In operation, a first concentrate is fed into the device through the first concentrate connection. The method and device then switch over from feeding the first concentrate into the device through the first concentrate connection to feeding the second concentrate into the device through the second concentrate connection. The switchover step can be performed at a predetermined time during an ongoing blood treatment or after a predetermined period of time.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: August 17, 2021
    Assignee: B. BRAUN AVITUM AG
    Inventor: Heiko Riemenschneider
  • Patent number: 11013838
    Abstract: A closed loop system and methods for pumping harvested fat from a patient donor site to a patient grafting site.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: May 25, 2021
    Inventor: Sarah Elizabeth Hagarty
  • Patent number: 10993614
    Abstract: OCT-enabled injection for vitreoretinal surgery may involve using an OCT image to detect when a surgical injector penetrates a desired tissue layer of the eye for receiving an injection. The injection may be triggered or automatically actuated based on the detection of the surgical injector from the OCT image.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: May 4, 2021
    Assignee: Alcon Inc.
    Inventor: Steven T. Charles
  • Patent number: 10980462
    Abstract: A micro-volume blood transfer device to facilitate the collection of small volumes of clean arterial blood from patients who may be volume restricted for blood loss such as low-birth weight infants.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: April 20, 2021
    Assignee: HUMMINGBIRD MED DEVICES, INC.
    Inventor: William Phillip Cash
  • Patent number: 10960127
    Abstract: An apparatus for measuring recirculation using thermodilution during extracorporeal blood treatment including a temperature varying unit arranged to cyclically heat and/or cool blood in a venous tube segment of the blood tube system for a quasi-continuous recirculation measurement; and a detecting device configured to measure a variation of a physical parameter resulting from the heating and/or cooling. The detecting device is arranged to detect, in a case free from recirculation, a first physical parameter and to detect, in a case afflicted with recirculation, a physical parameter varied by the cooling and/or heating of the blood by the temperature varying unit as a second physical parameter in the blood tube system. A method for measuring recirculation carries out appropriate steps.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 30, 2021
    Assignee: B. BRAUN AVITUM AG
    Inventors: Waldemar Janik, Silvie Krause
  • Patent number: 10960117
    Abstract: A catheter device having a catheter (24) in which a rotating shaft (25) which is made at least partially from a magnetic material is arranged, and a separating device which contains an annular body (27) surrounding the rotating shaft and having a cavity containing a magnetic body (13?), the magnetic body being arranged downstream from a point at which the shaft (25) exits the catheter (24) which it surrounds with respect to the direction of flow of the fluid through the catheter.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: March 30, 2021
    Assignee: ECP ENTWICKLUNGSGESELLSCHAFT MBH
    Inventors: Sami Er, Cornelia Simon, Joerg Schumacher, Reiner Liebing
  • Patent number: 10912871
    Abstract: The invention relates to an aspiration catheter for the extraction of thrombotic material from blood vessels, with a first and a second lumen, wherein the first lumen is distally provided with an aspiration opening and the second lumen of smaller cross section than the first lumen and extending coaxially in the distal region of the first lumen being provided with a lateral as well as distally located opening, said lateral opening reaching through the wall of the catheter. Within the first lumen a stabilization wire is movably arranged which terminates distally of the lateral opening of the second lumen but proximally of the aspiration opening of the first lumen.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: February 9, 2021
    Assignee: Qualimed Innovative Medizinprodukte GbmH
    Inventors: Manfred Gulcher, Martina Maria Schmitt
  • Patent number: 10874551
    Abstract: A method and apparatus for performing a surgical procedure is provided. The surgical procedure may be a phacoemulsification procedure but other procedures may employ the techniques disclosed. The design includes sensing, within the surgical site, for a material change in fluid flow relative to a predetermined threshold. Upon sensing the fluid flow materially differs from the predetermined threshold, the design temporarily increases aspiration vacuum pressure to the surgical site above a predetermined upper threshold toward a maximum vacuum level. The design applies electrically generated disruptive energy, including but not limited to laser and/or relatively low power ultrasonic energy, to the surgical site from a first point in time measured from when aspiration vacuum pressure is above the predetermined upper threshold to a second point in time where pressure falls below a predetermined lower threshold.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: December 29, 2020
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: Paul W. Rockley, Han Bor Fam
  • Patent number: 10857326
    Abstract: The present disclosure provides an apparatus that includes a first catheter having a proximal end and a distal end. The apparatus also includes a first tubular housing having a proximal end and a distal end. The first tubular housing is coupled to the first catheter proximal to at least one first outlet. The apparatus also includes one or more pressure sensors coupled to the distal end of the first tubular housing. The apparatus also includes a second catheter having a proximal end and a distal end. The distal end of the second catheter is configured to be positioned substantially within a second tubular housing coupled to one or more of the first catheter and the first tubular housing, when the second catheter is in a first position.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: December 8, 2020
    Assignee: Sanford Health
    Inventor: Patrick W. Kelly
  • Patent number: 10857335
    Abstract: A balloon catheter for treating aneurysms or other intraluminal target sites, having at least one bypass window through which blood flows temporarily and out at least one end hole, and a balloon mounted near the end hole, such that there is no need for repeated inflation/deflation cycles. The invention has an elongated tube, a balloon disposed between the most distal said window and said end hole, and at least two channels. A first channel passes from the proximal end of said tube to the bypass window to allow blood to flow into said window and out said end hole, and a second channel passing from the proximal end of said tube to said balloon to allow inflation material to enter said balloon.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: December 8, 2020
    Inventor: Daniel E. Walzman
  • Patent number: 10821276
    Abstract: The disclosed subject matter relates to a system and method for delivery of therapeutic agent to the inner ear. The system includes a plurality of micro-needles which can be delivered to the round window membrane by a delivery device, e.g. catheter, and is capable of controlled penetration of the round window membrane to create temporary and self-closing perforations. In some embodiments the micro-needles are hollow with a lumen for local drug delivery into the perforations. In other embodiments the micro-needles are solid and include a coating of therapeutic agent on exterior surface for delivery into the perforations.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: November 3, 2020
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Anil K. Lalwani, Jeffrey W. Kysar
  • Patent number: 10806891
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 20, 2020
    Assignee: Cook Regentec LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 10799244
    Abstract: Embodiments herein include devices and methods directed toward creating reverse flow within a vessel and thereby providing protection against embolic debris. Embodiments comprise a catheter and a plurality of occluders that are expandable and adjustable within a lumen to create low-pressure areas that reroute blood flow and embolic debris therein.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: October 13, 2020
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Benjamin M. Trapp, Michael J. Vonesh
  • Patent number: 10799676
    Abstract: Disclosed herein are steerable catheter assemblies and methods of steering catheters that utilize ball and socket mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction. Some embodiments include a catheter with two or more pull wires that flex the catheter, a first ball, a socket coupled to the first ball to form a ball and socket assembly, and an adjustment member coupled to the ball and socket assembly, such that the adjustment member is movable axially and rotationally relative to the ball and socket assembly. Two or more pull wires are connected to the socket, and the adjustment member engages the socket such that movement of the adjustment member adjusts the position of the socket relative to the first ball to thereby flex the catheter with the pull wires.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: October 13, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Bao Khuu, Matthew T. Winston, Asher L. Metchik, Eric Robert Dixon
  • Patent number: 10751522
    Abstract: A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. The cannula has a secondary opening proximal of the distal opening, and may include a movable tubular extension selectively extendable from the cannula via the secondary opening. The tubular extension may be in fluid connection with the cannula first lumen and/or a cannula second lumen. The tubular extension may have distal and/or side openings, with the openings providing antegrade fluid perfusion. The cannula second lumen may be separate from the first lumen, so that perfusion can be selectively provided to just the cannula distal opening, just the secondary opening/tubular extension, or simultaneously to both the distal opening and secondary opening/tubular extension.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: August 25, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Thomas Walther, Mark M. Dehdashtian, Teodoro S. Jimenez, Norma A. Garcia
  • Patent number: 10737084
    Abstract: Devices and methods for draining excess lymph fluid are disclosed. The device can be fixed to the blood vessel adjacent to the thoracic duct. The device can have a port for withdrawing lymph fluid exiting the thoracic duct. The device can have a cannula and/or subcutaneous port to draw the lymph fluid away from the thoracic duct and reduce hemostatic pressure in the lymphatic system.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: August 11, 2020
    Assignees: The Board of Trustees of the Leland Stanford Junior University, LXS, LLC
    Inventors: Matthew J. Callaghan, Joelle A. Faulkner, Kevin Zi Jun Chao, John Avi Roop, Stephen Arie Leeflang, Christian Scott Eversull
  • Patent number: 10736783
    Abstract: A dispensing assembly has a forward positioning section, an intermediate storage section, and a rearward operational section. The forward positioning section has an exterior end in a semi-spherical configuration with a forward passageway. The intermediate storage section has a storage chamber for fluid medication whereby the fluid medication may be fed through the forward passageway and out of the exterior end of the forward positioning section. A door in the intermediate storage section facilitates the addition of fluid medication. A piston is in the intermediate storage section. The rearward operational section drives the piston axially within the storage chamber whereby fluid medication in the storage chamber may be fed through the forward passageway and out of the exterior end of the positioning section into the ear of the pet.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: August 11, 2020
    Inventor: Thomas Paul Cogley
  • Patent number: 10716571
    Abstract: Surgical and percutaneous devices for closing tissue, for example, the left atrial appendage, may have an elongate body with a stiffened proximal portion, a flexible middle portion, a distal portion, a closure element with a loop having a continuous aperture therethrough, and a suture loop. The closure devices may have a malleable member attached to the elongate body that may be configured to retain a curve after a force is applied to the malleable member. System and methods for closing the left atrial appendage may utilize a closure device and a curved guide device, and the closure device and curved guide device may be self-orienting.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: July 21, 2020
    Assignee: SENTREHEART LLC
    Inventors: Gregory W. Fung, Alan L. Bradley, Robert L. Clark, III, Russell Pong, Russell A. Seiber
  • Patent number: 10716583
    Abstract: A system for aspirating thrombus includes a catheter having a supply lumen having a distal end and an aspiration lumen configured to couple to a vacuum source and having an interior wall surface and an open distal end, an orifice at or near the distal end of the supply lumen, in fluid communication with the interior of the aspiration lumen, the orifice located proximally of the open distal end of the aspiration lumen, wherein the orifice is configured to create a spray pattern that impinges on the interior wall surface of the aspiration lumen when a distal end of the aspiration catheter is immersed within an aqueous environment, and a disposable tubing set having a first conduit configured to couple the supply lumen of the aspiration catheter to a fluid source, and a pump component associated with the first conduit and configured to detachably couple to a drive unit.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: July 21, 2020
    Assignee: Walk Vascular, LLC
    Inventors: David M. Look, Mark Mallaby, Bradley S. Culbert
  • Patent number: 10709831
    Abstract: Method and apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a cassette having four inlets/outlets. A patient tube is connected to a patient connector, intended to be connected to a patient line for access to a peritoneal cavity of the patient. The patient tube comprises a flow pump for addition and removal of a peritoneal fluid between the cassette and the peritoneal cavity. The fluid is introduced into an intermittent bag controlled by an intermittent valve and then returned the same way back to the peritoneal cavity. Glucose is metered into the fluid entering the peritoneal cavity by means of a glucose pump. Glucose is replenished continuously or intermittently for keeping a concentration of the osmotic agent substantially constant in the peritoneal cavity. After treatment, the peritoneal fluid is drained to a drain bag, wherein the drain tube comprises a drain valve and an albumin filter.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: July 14, 2020
    Assignee: TRIOMED AB
    Inventors: Anders Wallenås, Lars Wramner, Stefan Landholm
  • Patent number: 10702415
    Abstract: A method and system provide a surgical hand piece including an aspiration line, a tip and a sensor. The tip is coupled with the aspiration line. The sensor is in the aspiration line. The sensor measures a change in at least one of flow through the aspiration line, pressure in the aspiration line and motion of an additional portion of the hand piece within the aspiration line.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: July 7, 2020
    Assignee: Alcon Inc.
    Inventor: Steven T. Charles
  • Patent number: 10695537
    Abstract: A method for dilating a stenotic region in an airway of a patient may include advancing a balloon catheter through the airway of the patient to position an inflatable balloon of the catheter within at least a portion of the stenotic region, maintaining a position of the catheter relative to the patient, and inflating the balloon of the catheter to dilate the stenotic region of the airway. A system for dilating a stenotic region in an airway of a patient may include a catheter shaft having an overall length of less than 70 cm, an inflatable balloon disposed along a distal portion of the catheter shaft, and a stylet.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: June 30, 2020
    Assignee: Acclarent, Inc.
    Inventors: Ketan P. Muni, Hung V. Ha, Chi Nguyen, Randy S. Chan, John Y. Chang
  • Patent number: 10661055
    Abstract: A device and method of treating proliferative disorders such as pancreatic cancer are described. Devices comprise an expandable mesh with two axial wings that seal against the inside of an enclosing blood vessel, creating an enclosed diffusion volume in the area subtended by the wings while permitting normal flow in the blood vessel through the ends of the mesh. A coaxial lumen provides for a guide wire, treatment drug tube, one or more flexible hypotubes and optionally electrical wires. The diffusion volume is set by the angle subtended by the wings causing the drug delivery to be radically directed toward a targeted tumor. Iontophoresis and electroporation electrodes on the mesh are used to directionally drive the drug through adjacent tissue and to temporarily increase the permeability of tissue through which the drug flows.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: May 26, 2020
    Inventor: Neal Scott
  • Patent number: 10652032
    Abstract: Methods and systems for generating a signature for a device include pre-charging a plurality of conductors to a first voltage level. A voltage leakage for each of the conductors is determined, and a device signature is generating based on the determined leakage.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: May 12, 2020
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Shih-Lien Linus Lu, Anthony Oates, Ming-Hsien Lin, Shou-Chung Lee
  • Patent number: 10632237
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: April 28, 2020
    Assignee: MINNETRONIX, INC.
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Patent number: 10624924
    Abstract: A method and device for treating cholesterol disorders includes administering at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnormal total cholesterol, abnormal LDL levels and/or abnormal HDL levels prior to treatment. Treatment according to the method results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnormal HDL levels. Each subsequent round of plasmapheresis is conducted weekly, but no more than twice per week.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: April 21, 2020
    Assignee: GRIFOLS, S.A.
    Inventors: Victor Grifols Lucas, Victor Grifols Roura
  • Patent number: 10597319
    Abstract: Disclosed is a piston press of the type used in the field of the dehydration of products to be dehydrated such as sludge from a purification plant. More particularly, it relates to a piston press including a pressing chamber supplied with sludge and able to manage air streams that it generates, and to a method for using such a press. In a preferred mode of embodiment, the piston press includes a pipeline having a water removal branch and arranged so as to remove water extracted during a sludge-pressing operation, and an air circulation branch that can channel the volumes of air circulating in the press during the operation thereof, so as to direct the vitiated air, i.e. air that has been brought into contact with the sludge during the implementation of the press, towards a deodorization system.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: March 24, 2020
    Assignee: SUEZ INTERNATIONAL
    Inventors: Pierre Emmanuel Pardo, Valerie Nastasi, Eric Judenne
  • Patent number: 10569007
    Abstract: A renal failure therapy system (10) includes: a dialyzer (102); a blood circuit (100) including a blood pump (120) in fluid communication with the dialyzer (102); a dialysis circuit (30) in fluid communication with the dialyzer (102); and at least one flow path insulator (150, 155) located in the dialysis circuit (30) or the blood circuit (100), the flow path insulator (150, 155) including a structure that separates liquid flowing within the flow path insulator (150, 155) into a plurality (e.g., two or more) of separated liquid segments (160) that create electrical isolation within the flow path insulator (150, 155).
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: February 25, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Sture Hobro, Olof Jansson, Erik Torgny, Peter Sendelius, Ingemar Palsson, Daniel Stahl
  • Patent number: 10561776
    Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: February 18, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
  • Patent number: 10549023
    Abstract: Methods, systems, and kits are provided for performing hemodialysis, hemodiafiltration, and peritoneal dialysis on a portable machine suitable for both clinical and home use. Peritoneal dialysate can be flowed into and out of the peritoneal cavity, and can also be regenerated within the system, without the need for introducing fresh dialysate. Common hardware and software can be utilized for both peritoneal dialysis and other forms of dialysis such as hemodialysis, hemofiltration, and hemodiafiltration, allowing for facile transition between different dialysis modes using the same dialysis machine.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: February 4, 2020
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Palmer David Updyke, Barry Fulkerson, Amaury De Leon De Leon, Michelle Bayly
  • Patent number: 10549041
    Abstract: The invention relates to an instrument head, comprising: an exit opening (23); a first feed line (11) for the feed of a first fluid; a second feed line (12) for the feed of a second fluid; a reservoir (24) for storing the fluid fed via the second feed line (12); wherein the reservoir (24) is in fluid communication with the first feed line (11) and/or is adapted to be brought in fluid communication with the first feed line (11) via at least a valve (25) arranged in the instrument head, to deliver fluid stored in the reservoir (24) via the exit opening (23).
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 4, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Andreas Fech, Klaus Fischer, Lars Blobel, Waldemar Wandel, Markus Enderle
  • Patent number: 10549010
    Abstract: The present invention relates to lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture. More particularly, the present invention relates to a method for preparing lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture, the method comprising the steps of: fragmenting fat tissue to isolate lipids by ultrasonic treatment or high pressure nozzle spray; removing the isolated lipids and fat tissue from which lipids were not isolated to sterilize. According to the present invention, lipids are removed from fat tissue only by physical treatment to maintain the volume thereof and microstructures such as cellular membrane as much as possible and thus the inventive scaffolds are useful for human tissue volume replacement.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: February 4, 2020
    Inventors: Heeyoung Lee, Hyunjin Yang, Jun Seok Lee, Ji Suk Choi
  • Patent number: 10537670
    Abstract: An intracorporeal device is provided for supporting heart function of a patient. The intracorporeal device is configured to be secured across at least two anatomical walls of the heart. The intracorporeal device is configured to be secured to one or more anatomical walls by a connector. The connector is arranged to be positioned across one or more anatomical walls.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: January 21, 2020
    Assignee: NUHEART AS
    Inventors: Vegard Tuseth, Shawn Patterson, Philip J. Haarstad, Knut Klepsvik
  • Patent number: 10537462
    Abstract: The present invention relates to a colostomy appliance with a flushable insert that can be removed and replaced without removing the outer bag, allowing for quicker, easier, and more sanitary disposal of fecal waste. The appliance is comprised of a faceplate with an attachment ring that has a lip and a catch, an outer colostomy bag with top and bottom openings that can be temporarily closed, and an insert made of a flushable material. The insert has an opening that fits over the attachment ring and is aligned and secured in its proper position inside the bag by the lip and the catch of the attachment ring. The present invention also provides a method for using the flushable insert with a colostomy appliance.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: January 21, 2020
    Assignee: Wildhatch, LLC
    Inventors: John D. Hatchett, Scott A. Fengler
  • Patent number: 10512718
    Abstract: Systems and methods for cleaning body cavities are presented. Some embodiments reduce size of fecal matter pieces within an evacuation conduit. Some comprise devices and methods for purging an evacuation conduit. Some comprise reduced cross-sectional profiles of a cleaning device. Some protect intestinal tissue by preventing exposure to excessively high and low pressures.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: December 24, 2019
    Assignee: Motus GI Medical Technologies Ltd.
    Inventors: Boris Shtul, Alexey Morochovsky, Alexander Banzger, Noam Hassidov
  • Patent number: 10507191
    Abstract: The subject invention provides materials methods for reducing infections in subjects. The materials methods utilize chlorhexidine, which has been found to be surprisingly non-toxic. The lack of toxicity facilitates the use of chlorhexidine in contexts that were not previously thought to be possible.
    Type: Grant
    Filed: March 31, 2018
    Date of Patent: December 17, 2019
    Assignee: INNOVATION TECHNOLOGIES, INC.
    Inventors: Carolyn L. Twomey, Gareth Clarke, Samuel Zaidspiner
  • Patent number: 10493257
    Abstract: Devices and methods for cleaning a port, including a port reservoir and other aspects of the port, whereby a trocar/cannula assembly is introduced to the port reservoir. The trocar is withdrawn from the port reservoir, providing access to the reservoir. A cleaning member is then advanced through the cannula, and can remove an unwanted material therefrom.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: December 3, 2019
    Assignee: AngioDynamics, Inc.
    Inventors: Bradley D. Chartrand, Jeffrey Willis
  • Patent number: 10449284
    Abstract: A handheld personal communication apparatus for dialysis includes: a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: October 22, 2019
    Assignees: Baxter Interntional Inc., Baxter Healthcare SA
    Inventors: Bijan Elahi, Ying-Cheng Lo, Vikram Prabhakar Mehendale
  • Patent number: 10441300
    Abstract: A catheter comprises an elongated carrier and a balloon carried by the carrier in sealed relation thereto. The balloon has an outer surface and is arranged to receive a fluid therein that inflates the balloon. The catheter further comprises a shock wave generator within the balloon that forms mechanical shock waves within the balloon, and a medicinal agent carried on the outer surface of the balloon. The medicinal agent is releasable from the balloon either before or in response to the shock wave.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: October 15, 2019
    Assignee: SHOCKWAVE MEDICAL, INC.
    Inventor: Daniel Hawkins
  • Patent number: 10398811
    Abstract: Medical wound irrigation systems are described that may be used in environments such as hospitals and first aid stations, and for military applications, e.g., for medics and along transport routes for the wounded. The irrigation systems can provide continuous variable pressure for irrigating a wound. For example, in some embodiments, a medical irrigation system can be used to provide a steady pressure level while irrigating about one liter of solution in less than about one minute, e.g., to assist during wound irrigation and debridement. The medical irrigation system may include an air-powered irrigation device, which pressurizes an irrigation solution, such as a cleansing fluid, to create an ejection force. In some embodiments, the medical irrigation system can include a replaceable bottle cap with an inlet for connecting to a source of pressurized fluid (e.g., pressurized gas, such as pressurized air) and an outlet for the irrigation solution/cleansing fluid.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: September 3, 2019
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Thang Nguyen, Michael Wadman, Richard Morris, Vincent Morris