Abstract: The present invention provides an oral device that is inserted into the mouth of a patient during sedation to minimize the risk of airway obstruction and method of use. The oral device comprises a mouthpiece. A gas inlet conduit, a gas outlet conduit, and a fluid outlet conduit are adjacent to the vestibular portion of the mouthpiece. The gas inlet conduit may be used to provide oxygen to the mouth of a patient. The gas outlet conduit may be used to remove end-tidal carbon dioxide from the mouth of a patient. The fluid outlet conduit may be used to remove fluid from the mouth of a patient. The oral device may also include a tongue stabilizer to minimize movement of the tongue. The mouthpiece may include fluid outlet ports to remove fluid from the mouth of a patient and an instrument passage to allow medical instruments to pass through the oral device.

Abstract: In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.

Abstract: A bone void plug includes a plug body that extends along a longitudinal axis between a proximal face and a distal opening and a recessed opening that extends from the distal opening toward the proximal face. The recessed opening is configured to receive a bone void filler.

Abstract: A steerable laser probe may include a handle having a handle proximal end and a handle distal end, an actuation structure of the handle, a housing sleeve, a shape memory sleeve at least partially disposed within the housing sleeve, and an optic fiber disposed within the shape memory sleeve and within an inner bore of the handle. A compression of the actuation structure may be configured to gradually curve the optic fiber. A compression of the actuation structure may be configured to gradually straighten the optic fiber. A decompression of the actuation structure may be configured to gradually curve the optic fiber. A decompression of the actuation structure may be configured to gradually straighten the optic fiber.

Abstract: The invention provides injectable, biofunctional agent-containing calcium phosphate cement bone pastes for bone tissue engineering, and methods of making and using the same.

Abstract: A delivery system for delivering fluidic media to a user having a second housing portion configured to be selectively operatively engaged with and disengaged from a first housing portion, the first housing portion and the second housing portion configured to be slidable relative to each other to operatively engage each other; and a fluid connector supported by one the housing portions in a position to engage a reservoir supported by an other of the housing portions in a case where the first housing portion and the second housing portion are slid relative to each other to operatively engage each other.

Abstract: An irrigation system for irrigation of a body cavity includes a reservoir, with an inlet for pouring liquid into the reservoir, an insertion member defining an insertion end for insertion into a body cavity through a body opening of a human being, the insertion member defining at least one opening, and a liquid tube fluidly connecting the reservoir with the insertion member. The reservoir has front and rear walls formed of a flexible, non-elastic polymer material, with the walls having edges sealed together. The reservoir has an upper liquid chamber and a lower liquid chamber, with the two chambers being separated by a first one-way valve.

Abstract: An enema includes a liquid in a dispenser having a bottle, a nozzle attached to the bottle, and a valve. The valve may be a membrane having a slit and a thickness of at most 0.90 mm. The valve may be attached to the bottle or it may be attached to the nozzle. The enema can be administered more easily, with a lower amount of force. A method of bowel cleansing includes inserting the enema into a rectum and applying a compression force to the enema bottle.

Abstract: This patent relates to devices that can be manipulated by a user to expel or draw in a material. In one example, a hand-operable vacuum device can include an interface portion configured to contact a material. The hand-operable vacuum device can also include a deformable portion that extends along an axis that passes through the interface portion and wherein the deformable portion includes at least one longitudinally-oriented resilient structure that extends generally parallel to the axis.

Abstract: An instrument for delivering a suture transfascially may include a handle, a shaft extending from the handle, and a pair of needles that are moveable to an extended position beyond the end of the shaft. One or more sutures are carried by the instrument and may be delivered transfascially. A transfascial suture assembly includes a suture having first and second segments and an intermediate segment therebetween. A force distributing member is locatable at the intermediate segment. Suture retainers may be provided at the end of each suture segment, and may have a connection that is moveable relative to the suture segment. A method of delivering transfascial sutures includes inserting a twin-needle instrument loaded with one or more sutures into an abdominal cavity and deploying, from within the abdominal cavity, the suture carrying needles through a soft tissue repair patch and then through at least part of the abdominal wall.

Abstract: A system in accordance with embodiments of the present invention includes a cannula interconnected to a collection vessel by a flexible conduit. The collection vessel can comprise an impermeable or permeable collection vessel. The collection vessel is contained within a collection container, and can feature a tapered end. An air inlet may be provided in the flexible conduit and/or in a collection canister lid.

Abstract: This patent relates to devices that can be manipulated by a user to expel or draw in a material. In one example, a hand-operable vacuum device can include an interface portion configured to contact a material. The hand-operable vacuum device can also include a deformable portion that extends along an axis that passes through the interface portion and wherein the deformable portion includes at least one longitudinally-oriented resilient structure that extends generally parallel to the axis.

Abstract: An electrosurgical controller with output RF energy control. At least some of the illustrative embodiments are electrosurgical controllers configured to change a first output voltage on the first active terminal relative to the first return terminal by selective control of a number of turns of the primary winding of a transformer used to create the output voltage.

Abstract: A syringe comprises a barrel with a plunger in slidable and sealing engagement therein, and a needle attached to one end of the barrel. The barrel has an aspiration device in the form of manually-operable resilient portions, which can be operated to cause a pressure differential in the barrel, the pressure differential then being used to perform aspiration. The resilient portions are preferably formed by localized reductions of wall thickness in the external surface of the barrel.

Abstract: A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma while controlling the flow of material through the pneumostoma and a pneumostoma aspirator for pneumostoma care. The pneumostoma aspirator includes a bulb or syringe for applying positive or negative pressure, a tube for entering the pneumostoma and a limiting device for limiting the depth of insertion of the tube into a pneumostoma. The pneumostoma aspirator may also be used to introduce irrigation fluid into the pneumostoma and/or remove irrigation fluid and discharge from the pneumostoma.

Abstract: An enema includes a liquid in a dispenser having a bottle, a nozzle attached to the bottle, and a valve. The valve may be a membrane having a slit and a thickness of at most 0.90 mm. The valve may be attached to the bottle or it may be attached to the nozzle. The enema can be administered more easily, with a lower amount of force. A method of bowel cleansing includes inserting the enema into a rectum and applying a compression force to the enema bottle.

Abstract: A system in accordance with embodiments of the present invention includes a cannula interconnected to a collection vessel by a flexible conduit. The collection vessel can comprise one or more syringe bodies. The syringe bodies are provided with tissue removed from a body using the cannula by a tissue transfer channel. As a result, multiple syringe bodies can be loaded with tissue, without requiring manual handling of that tissue. Alternatively or in addition, a collection bag can be provided for receiving tissue removed from a body using a cannula. The tissue collection bag can include a filter. A collection vessel comprising a collection bag can be used in combination with a collection vessel comprising one or more syringe bodies.

Abstract: A vessel for use in rinsing a user's nasal cavities includes a main body, a spout, a self-sealing nozzle, and a flow control valve actuable by the user. The spout extends off of the main body and the elastomeric nozzle attached to the spout defines an outer skirt having a deflectable free end upon contact with the walls of the user's nasal cavity. A vacuum breaker valve is formed in a top portion of the main body for actuation by the user to control the flow of a fluid positioned in the vessel out of the nozzle. The main body may include gripping indentations along opposing sidewalls thereof. The spout may be integrally formed with the main body, and the spout and the nozzle may be detachably connected.

Abstract: The present invention provides for the transplantation of tissue from a donor site in a body to a recipient site. The device includes an outer chamber having an interior volume in which a perforated inner chamber can be placed. During the aspiration of tissue, a vacuum is formed in the interior volume of the outer chamber, to draw tissue from a cannula into the perforated inner chamber. The perforations are sized such that fat is collected within the inner chamber, while fluids and other materials are drawn through the perforations, away from the collected fat. For reinjection, the inner chamber can be removed from the outer chamber, and a sleeve positioned to cover the perforations and thereby form a syringe body that can be interconnected to a needle and plunger for reinjection of the collected fat.

Abstract: A system in accordance with embodiments of the present invention includes a cannula interconnected to a washing reservoir by a flexible conduit. The washing reservoir has an outlet that is connected to the inlet of a tissue collection reservoir. Washed tissue can be removed from the washing reservoir by tipping or otherwise causing the outlet of the washing reservoir to be covered by washed tissue. Tissue collected in the tissue collection reservoir can be readied for injection into a body by removing an inner or filter chamber from an outer chamber and blocking holes in the body of the inner chamber to use the inner chamber as part of a syringe.

Abstract: A system in accordance with embodiments of the present invention includes a cannula interconnected to a collection vessel by a flexible conduit. The collection vessel can comprise one or more syringe bodies. The syringe bodies are provided with tissue removed from a body using the cannula by a tissue transfer channel. As a result, multiple syringe bodies can be loaded with tissue, without requiring manual handling of that tissue. Alternatively or in addition, a collection bag can be provided for receiving tissue removed from a body using a cannula. The tissue collection bag can include a filter. A collection vessel comprising a collection bag can be used in combination with a collection vessel comprising one or more syringe bodies.

Abstract: Described herein is a novel drug delivery assembly having particular applicability to the field of orthopedic and surgical medicine. The devices and assemblies described herein enable the efficient application and retention of potentially expensive therapeutic materials to very specific locations, particularly those associated with voids in bone and tissue. One particularly unique aspect of the present invention involves the introduction of constructs which promote the retention of therapeutic material in the target area of application for beneficial use, for example by forming a proximal barrier that prevents leakage of the therapeutic material out of the target area. Additionally, the present invention provides unique devices and methods for surgical introduction of such constructs.

Abstract: An ultrasonic surgery apparatus capable of setting surgical conditions properly in accordance with hardness of a nucleus lentis and performing surgery with efficiency is disclosed. The ultrasonic surgery apparatus includes an ultrasonic vibration inducing unit, having an ultrasonic chip which induces ultrasonic vibrations to fragment and emulsify a nucleus lentis, an input unit which inputs a judgment result of hardness of the nucleus lentis, and a setting unit which sets a condition of the ultrasonic vibrations thereafter based on the inputted judgment result.

Abstract: A manual-driven inflation-powered electronic blood pressure measuring apparatus includes an inflation unit to generate pressurized air by a user through hand squeezing, a power generation unit to receive the pressurized air to generate and output electric power, an electronic blood pressure measurement unit to receive the electric power output from the power generation unit and the pressurized air from the inflation unit to inflate an air pouch, and a sensor to detect a person's blood pressure signals in cooperation with the inflation pouch, and outputs a measurement result through an output unit.

Abstract: A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within the blood container for expressing blood fractions separated during centrifugation of the container through a first port mounted at one end of said container, a second port mounted on the plunger, and a third port mounted on a plunger rod attached to the plunger.

Abstract: A shape memory shutter device for controlling the rectum of a disabled person, comprises a section of conduit to be connected to the rectum of the disabled person, and a shutter which controls the passage through the conduit section and actuated by a shape memory actuator. The shutter comprises a plurality of petals positioned circumferentially around the conduit section and able to move between a closed and an open position. The actuator comprises shape memory wires associated to the petals which are supplied with electrical current to cause opening of the petals.

Abstract: A sigmoidoscope comprises at least one disposable part, in combination with a device for insufflation of a body cavity with a medium via the sigmoidoscope, the medium being susceptible to contamination by a contaminant during use of the sigmoidoscope. The insufflation device and the sigmoidoscope are connected, or adapted for connection, to one another. The sigmoidoscope and/or the insufflation device are provided with a disposable contamination prevention device, or being so formed and arranged, that no non-disposable part of the sigmoidoscope and no non-disposable part of the insufflation device is exposed to any contaminated medium during use of the sigmoidoscope.

Abstract: For safely inserting a catheter into a chest cavity of a child or corpulent patient to be retained therein and for preventing atmospheric air from proceeding into the chest cavity during a removal of a penetrating needle, discharge equipment for medical procedures is provided which equipment includes a connector cap and a storage bottle detachably connectable to each other, a connector to be connected to the catheter retained in the patient, a check valve including an outer periphery covered by a protective cover and being openable only toward a storage bottle side, and a coupling device to the storage bottle mounted on the connector cap. The storage bottle is a hollow container including an inlet port and a discharge port, a detachably connecting device for the connector cap mounted on the inlet port, and a check valve openable only toward an exterior of the storage bottle is mounted on the discharge port.

Abstract: The methods and devices disclosed provides for the delivery of agents to an orifice cavity and subsequent aspiration of the agent and orifice contents from the orifice cavity and related areas. In one form, the delivery and aspiration system comprises an agent delivery sub-assembly, an aspiration sub-assembly and a device tip sub-assembly. The subassemblies operate to first deliver an agent contained within the device to an orifice cavity and after an optional time delay, subsequently aspirate the delivered agent and orifice contents from the orifice cavity and related areas. In another form, a removable reservoir is provided whereby the aspirated agent and orifice contents from the orifice are assayed either independent of or within the device itself.

Abstract: By providing a mixture of surfactants and water, with the water content ranging between bout 40% and 95% by weight based upon the weight of the entire composition, a unique, improved, liquid based foaming soap formulation is realized which is useable for a wide variety of applications, including wet shaving and dry shaving. In the preferred embodiment, the improved liquid based foaming soap formulations incorporate one or more therapeutic active in sufficient quantities to assure its efficacy. As a result, the formulation is useable for a wide variety of medical applications for preventing, treating, or reducing the spread or transmission of bacteria, virus, infections, and the like.

Abstract: A drug dispensing system for substantially preventing addictive use of drugs. The system has multiple dispensers each containing a drug such as nasal spray. The drug in at least one of the dispensers is diluted to a first pre-selected concentration level with a diluent and the drug in at least a second one of the dispensers is diluted to a second lower pre-selected concentration level with a diluent.

Abstract: A microsurgical irrigation device, comprising a first tube for supplying liquid from a liquid source, the first tube having a first end in communication with the liquid source, and further having a second end; an elastomeric bulb connected to the second end of the first tube, wherein the bulb is in communication with the first tube; a second tube for dispensing liquid expelled from the elastomeric bulb, the second tube having a first end connected to the bulb and further having a second end, wherein the second tube is in communication with the bulb; an inlet, one-way, valve preventing liquid from returning from the bulb into the first tube when the bulb is actuated, and allowing liquid to flow from the first tube into the bulb when the bulb is released; and an outlet, one-way, valve preventing liquid from exiting the bulb until a predetermined amount of pressure is provided by bulb actuation.

Abstract: A device and method for treating an illness or infection in the repiratory tract of a body is provided. The device administers an antimicrobial mist directly to the tissues to be treated, which coats the tissues in the respiratory tract where the infection is colonizing. The administration of the mist is reapplied in order to maintain a predetermined antimicrobial tissue density concentration of a uncompounded silver colloid suspended antimicrobial substance for a predetermined time period.

Abstract: The present invention provides an oral medicine dispenser for the administration of a single pre-measured dose, which dispenser comprises a body having a collapsible reservoir portion and an elongate dispensing tube portion extending from the reservoir portion, wherein the reservoir portion holds, in use, a single dose of a fluid oral medicament and the dispensing tube portion has an end cap, whereby on opening of the end cap the collapsible reservoir portion may be manually squeezed to collapse the reservoir portion sufficiently to dispense substantially all of, or at least a major part of the medicament dose through the dispensing tube portion.

Abstract: A system for safely irrigating nasal and sinus cavities using a portable and reusable device which can be conveniently coupled to a fluid container, wherein the system includes an adapter end for coupling to the fluid container, an insertion end which directs fluid from the fluid container into the nasal and sinus cavities while preventing damage thereto by preventing insertion of the insertion end into the nasal cavities beyond a predetermined length, and a curved section of tubing which is coupled to the adapter end and the insertion end, wherein the curved section of tubing makes the user hold the fluid container in a correct position for directing solution from the fluid container into the nasal and sinus cavities.

Abstract: A sigmoidoscope comprising at least one disposable part (1), in combination with means (10) for insufflation of a body cavity with a medium via the sigmoidoscope; said medium being susceptible to contamination by a contaminant (as herein defined) during use of the sigmoidoscope, said insufflation means (10) and said sigmoidoscope (eg part 1) being connected, or adapted for connections one to the other; the sigmoidoscope and/or the insufflation means being provided with disposable contamination prevention means (18), or being so formed and arranged, that no non-disposable part of the sigmoidoscope (eg 15) and no non-disposable part of the insufflation means is exposed to any contaminated medium during use of the sigmoidoscope.

Abstract: A dose dispensing device such as a medicine dropper is improved by putting a dosing scales such as a body weight scale directly on the dose dispensing device. This improved device is used to simultaneously calculate and measure an exact dose of liquid medicine, based on the body weight of the patient.

Abstract: A nasal aspirator having a stem, a tip and a bulb. The stem having an inner lumen from a top to a bottom. The tip comprising of an aperture at a point that arches from a base, wherein the base is secured to the top of the stem. The bulb having a ribbed opening into an inner hollow cavity. The bottom of the stem being inserted through the ribbed opening and into the inner hollow cavity so that the top of the stem is secured at the ribbed opening of the bulb.

Abstract: Nasal, sinus and otic packings exhibiting a less adherent surface when in contact with tissue and being less traumatic on removal are prepared. In a first embodiment, polyvinyl acetal foamed packing material undergoes a surface modification imparting a non-adherent hydrogel coated surface. The surface modification is accomplished after final processing and fabrication of the packing product shape. The packing material is subjected to either an atomized spray of an aqueous solution of ethyl alcohol or a polyvinyl acetate/polyvinyl alcohol copolymer. In another embodiment, a foamed polyvinyl acetal material is produced by crosslinking polyvinyl alcohol with an organic compound containing two hydroxyl reactive groups in the presence of an inert gas. An aqueous solution containing polyvinylpyrrolidone is mixed into the reaction during crosslinking.

Abstract: The portable, locally washing hygienic device has a water container of a flexible synthetic resin film member, a water supply tube mounted on the water container and acting as a water passage, a spray nozzle mounted on an upper portion of the water supply tube, and a valve assembly interposed between the spray nozzle and the water supply tube, in which a lower portion of the water supply tube located within the water container is joined together through a connecting member with an inner surface portion of the water container by thermally fusing or otherwise.

Abstract: A needle for use with an apparatus for injecting fluid into a pierced body orifice has a hollow body having an axis and an internal bore along the axis, a blunt, closed first end, an open second end with an interface to a closure for attachment to a reservoir, and one or more side openings at substantially a right angle to the axis communicating from the internal bore to outside the hollow body. The needle may be curved or straight. A fluid injection system based on the needle uses such as squeeze bottles or syringes to express material through the needle.

Abstract: A needle for use with an apparatus for injecting fluid into a pierced body orifice has a hollow body having an axis and an internal bore along the axis, a blunt, closed first end, an open second end with an interface to a closure for attachment to a reservoir, and one or more side openings at substantially a right angle to the axis communicating from the internal bore to outside the hollow body. The needle may be curved or straight. A fluid injection system based on the needle uses such as squeeze bottles or syringes to express material through the needle.

Abstract: A porous absorbent material that comprises a water-insoluble, water-swellable absorbent polymer. The absorbent material comprises a polyether and/or a polycation bonded to the absorbent polymer whereby the contact angle of blood on a surface of the absorbent material attains from about 0 degree to about 40 degree. Because of the improved wettability with liquids as well as the porous structure, the absorbent material can provide higher absorbent characteristics with liquids, in particular with blood.

Abstract: A mixer for the mixing of components, comprising a continuous inner surface that is non-retaining to the components, wherein a first portion of the inner surface opposably contacts a second portion of the inner surface during mixing, and a means for supplying a component to the mixer; a kit including the mixer, and methods of using the mixer to prepare compositions.

Abstract: An electrosurgical instrument that is capable of generating high-quality RF energy at a first frequency best suited for delicate, precise. and quick-healing cutting procedures with low leakage currents using a unipolar handpiece, and also provides high-quality RF energy at a second frequency best suited for coagulation for use with a bipolar handpiece. In a preferred embodiment, the first frequency is in the range of about 3.8-4.0 Mhz, and the second frequency is in the range of about 1.7-2.0 Mhz. The instrument is preferably configured so that both a unipolar handpiece and a bipolar handpiece can be used during a surgical procedure, though not at the same time, without having to activate any switches on the instrument. This has the advantage of providing the surgeon all the benefits of both electrosurgical modes while not jeopardizing the crucial sterile field.

Abstract: The present invention relates to a haemostatic circumcision bandage comprising a bandage body made of a pliable waterproof material and of a unitary configuration. The bandage has a shaft supporting portion adapted to be wrapped around an entire penile shaft protecting it against contamination and a body attachment portion connected to the shaft supporting portion, which is adapted to be temporarily attached to a wearer's body and provided to keep the bandage in place. The bandage also has a resilient pad placed on the shaft supporting portion, which is adapted to facilitate haemostasis by means of applying a gentle even compression, as well as an absorbent pad placed over the resilient pad, which is provided to help absorb blood and promote healing a wound caused by circumcision.

Abstract: A flexible, sterile, trimable device which gently and continuously removes unwanted fluid from an operating field during surgery by wicking the fluid into a mat having a high wicking property. A flexible suction tube having one end embedded in the mat removes fluid from the mat, thereby preventing the mat from becoming saturated. One embodiment of the invention is as a surgical swabber where one end of a length of semi-rigid tube is embedded in the mat and the other end is connected to a flexible suction tube. Another embodiment of the invention is as a platform for microsurgery where a membrane having a plurality of holes is applied to one side of the mat. The membrane supports the tissue being worked on and is preferably a contrasting color. Fluid passing into the holes is wicked into the mat where it is subsequently removed by the suction tube. The platform can be oriented in any position and does not slip on the tissue on which it is placed.

Abstract: A liquid dispenser assembly for medical applications includes a container holding a predetermined quantity of a therapeutic liquid in a storage chamber. The container has a wall or panel provided with a port. A dip tube is disposed in the chamber and extends from the port to a lower portion of the storage chamber. The disepnser assembly further includes a hollow compressible dispenser body. An applicator tube is attached at one end to the dispenser body and extends at a free end, i.e., an end opposite the dispenser body, into the dip tube. The applicator tube is removable from the dip tube after an expansion of the dispenser body from a collapsed configuration and a concomitant drawing of an aliquot of the liquid into the dispenser body through the dip tube and the applicator tube.

Abstract: A mixer for the mixing of a first and a second component, comprising a flexible pouch which contains said first component and which has an inner surface that is non-retaining to the components; means for supplying the second component to the chamber for mixing with the first component; and a neck attached to said pouch.

Abstract: A fine-needle aspirator for collecting a biosample from a subject into a closed sterile system. The aspirator is adapted for use with a variety of needles and comprises a motor drive pump capable of continuous suction in a biosample collection system. The biosample collection system may comprise a biosample connector such as elastomeric tubing in communication with the needle and a collection space in a biosample container whereby a biosample collected by the needle may be transferred to the collection space. A flushing substance flushes the biosample through the biosample collection system. Additives may be added to the biosample after collection in order to treat, preserve or analyze the biosample.