Devices Transferring Fluids From Within One Area Of Body To Another (e.g., Shunts, Etc.) Patents (Class 604/8)
  • Patent number: 12029683
    Abstract: An ocular implant including a drug releasing element and having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: July 9, 2024
    Assignee: Alcon Inc.
    Inventors: Wendy Blanda, Rhett Schiffman
  • Patent number: 12017413
    Abstract: A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.
    Type: Grant
    Filed: March 10, 2023
    Date of Patent: June 25, 2024
    Assignee: Xeltis AG
    Inventors: Matthew Mannarino, Jon McGrath, Cory Leeson, Mohammed El-Kurdi, Danielle McDowell, Kermit Santiago, J. Christopher Flaherty
  • Patent number: 12011557
    Abstract: Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: June 18, 2024
    Assignee: CereVasc, Inc.
    Inventors: Carl Heilman, Adel M. Malek, David A. Rezac, Timothy W. Robinson, Joseph Ting
  • Patent number: 11951270
    Abstract: Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: April 9, 2024
    Assignee: CereVasc, LLC
    Inventors: Adel M. Malek, Carl Heilman, David A. Rezac, Jack B. Sattell, Anthony Maiorano
  • Patent number: 11937818
    Abstract: An end effector for use by a surgeon to staple an anatomical structure of a patient during a surgical procedure includes an anvil and a cartridge. Each of the anvil and the cartridge has a face that is positionable on the anatomical structure. The anvil is coupled to the cartridge at first and second ends. The anvil is movable relative to the cartridge to define a first gap between the faces at the first ends that is different from a second gap between the faces at the second ends.
    Type: Grant
    Filed: October 10, 2022
    Date of Patent: March 26, 2024
    Assignee: Standard Bariatrics, Inc.
    Inventors: Jonathan Thompson, Bennie Thompson, Richard P. Nuchols, Russell L. Holscher
  • Patent number: 11925640
    Abstract: Provided herein are methods and materials for improving arteriovenous fistula (AVF) maturation and/or maintaining AVF functionality. For example, methods and materials for using one or more senolytic agents to improve AVF maturation, to maintain AVF functionality, and/or to maintain the patency of an AVF are provided. Methods and materials for using one or more senolytic agents to maintain functionality and/or patency of a venous graft (e.g., a venous graft that bypasses an occluded artery) also are provided.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: March 12, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Karl A. Nath, James L. Kirkland, Tamar Tchkonia
  • Patent number: 11911262
    Abstract: An apparatus for delivering an implant to an eye using a ratchet drive. Some embodiments of an apparatus for delivering an implant to an eye may comprise a gear rack configured to be coupled to the implant, a forward gearwheel, an input gearwheel meshed with the forward gearwheel, an idler gearwheel meshed with the input gearwheel, and a reverse gearwheel meshed with the idler gearwheel. An actuation lever may be configured to rotate the input gearwheel. Some embodiments may additionally comprise a pivot arm that may be operable to selectively engage the forward gearwheel and the reverse gearwheel to the gear rack.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: February 27, 2024
    Assignee: Alcon Inc.
    Inventor: R. Mitchell Sherry
  • Patent number: 11904120
    Abstract: Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.
    Type: Grant
    Filed: December 20, 2022
    Date of Patent: February 20, 2024
    Assignee: NXT Biomedical, LLC
    Inventors: Glen Rabito, Joseph Passman, Robert C. Taft, Stanton J. Rowe, Robert S. Schwartz, Alexander Siegel
  • Patent number: 11890210
    Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to delivering a variable length stent within a patient. In one example, a stent may include a body comprising coils about a longitudinal axis of the stent and along the length of the stent between a proximal end and a distal end in a substantially helical pattern. The coils may define a lumen along the longitudinal axis through the center of the body. A distal tube may have a wall extending from the distal end of the body. A first aperture may extend through the wall of the distal tube into the lumen. A distal retention member may extend from the distal tube. A distal suture may have a mid-portion. The mid-portion may extend through the first aperture.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: February 6, 2024
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Michael S H Chu, Mayur K. Patel, Sacha Tang
  • Patent number: 11878103
    Abstract: Various exemplary methods, systems, and devices for joint to pump elevation level user interfaces, autocalibration for joint elevation, and joint pressure estimation are provided. In general, an arthroscopic pump can be configured to estimate fluid pressure at a surgical site, e.g., at a joint, to provide an accurate indication of fluid pressure to users. In an exemplary embodiment, the fluid pressure estimation is based on a fluid pressure measurement at the pump that is adjusted at the pump, e.g., by a processor at the pump that executes instructions stored in a memory at the pump, using one or more control algorithms that adjust for one or more factors, such as pressure loss in tubing and sheath through which fluid flows between the pump and the surgical site and elevation difference between the pump and the surgical site.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: January 23, 2024
    Assignee: Medos International Sarl
    Inventors: Oliver Dumas, Eduard Grinberg, Andre Francisco Guilherme, Michael Confoey, Jacob A. Marks
  • Patent number: 11872158
    Abstract: Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device, tool, or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Some systems described here may be configured to cut or tear the trabecular meshwork with the body of an elongate member located within Schlemm's canal. Other tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: January 16, 2024
    Assignee: SIGHT SCIENCES, INC.
    Inventors: David Y. Badawi, Daniel O'Keeffe, Paul Badawi
  • Patent number: 11865284
    Abstract: The present disclosure provides a fluidic device including (a) a first channel including a first inlet and a first outlet, (b) a second channel including a second inlet and a second outlet, wherein the second inlet of the second channel is in fluid communication with the first outlet of the first channel, and (c) a sensor positioned between the first outlet and the second inlet, wherein the sensor includes a sensor configured to deflect in response to a flow between the first channel and the second channel.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 9, 2024
    Assignees: University of Connecticut, Yale University
    Inventors: Kazunori Hoshino, Davina Jaiswal, Mengdi Bao, Garrett Soler, Ariane Garrett, Ryan Grant, Michael Diluna, Hitten Zaveri
  • Patent number: 11850149
    Abstract: A prosthetic heart valve and delivery system adapted to facilitate transapical or transfemoral implantation of a prosthetic heart valve, the delivery system comprising an elongated sheath or shaft have one or more loop stabilization wires adapted to circumscribe and crimp a metallic stent, the loop stabilization wires releasable with retraction of an engagement pin to expand the metallic stent and anchor the same in native tissue within the circulatory system of a patient.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: December 26, 2023
    Inventors: Brandon Walsh, Matthew F. Ogle
  • Patent number: 11844893
    Abstract: An apparatus for shunting blood includes a flow-indication chamber shaped to define an entry port and an exit port, and one or more moveable objects disposed within the flow-indication chamber and configured to move in response to a flowing of the blood from the entry port to the exit port. At least a portion of a wall of the flow-indication chamber is transparent so as to expose the moveable objects to sight. Other embodiments are also described.
    Type: Grant
    Filed: January 16, 2022
    Date of Patent: December 19, 2023
    Assignee: INSPIRE M.D LTD.
    Inventors: Jesse Drake, Justin McCarthy, Itshak Cohen
  • Patent number: 11839379
    Abstract: Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial fibrillation.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: December 12, 2023
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Kurt Amplatz, Gary A. Thill, Pat Russo, Xiaoping Gu, Jana Santer
  • Patent number: 11793839
    Abstract: Described is a system for affecting intestinal microbial flora. The system includes an intestinal sleeve that is implanted in a patient and bypasses a section of the intestine; and probiotics, prebiotics or pharmacologic therapy used in combination with the intestinal sleeve. Also described are related methods.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: October 24, 2023
    Assignee: Metamodix, Inc.
    Inventors: Kedar R. Belhe, Todd Stangenes
  • Patent number: 11779448
    Abstract: A mesh for repair/prevention of a parastomal hernia during ostomy treatment is disclosed. More specifically, a pre-molded mesh having a unique shape to provide support to the abdominal wall adjacent a stoma formed during an ostomy procedure to prevent/repair formation of a parastomal hernia is disclosed which also provides a clearance channel through which the bowel can pass in a manner that prevents collapse or obstruction of the exposed segment of the bowel.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: October 10, 2023
    Inventor: Zhongqiu Zhang
  • Patent number: 11737760
    Abstract: The present disclosure concerns embodiments of an implantable perfusion device that can be implanted in an injured blood vessel to control bleeding without occluding the vessel. In one specific implementation, the perfusion device can be implanted percutaneously into a patient's descending aorta to control bleeding at the site of a ruptured portion of the aorta (known as torso hemorrhage) while still allowing for the antegrade flow of blood from a location upstream of the ruptured portion of the aorta to a location downstream of the ruptured portion of the aorta. The perfusion device can be left inside the patient as the patient is transported to a medical facility where the injury can be repaired. Following repair of the vessel, the perfusion device can be withdrawn from the patient.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: August 29, 2023
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Bryan W. Tillman, William W. Clark, Sung Kwon Cho, Youngjae Chun
  • Patent number: 11730614
    Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 22, 2023
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Daniel Tuck, Martyn G. Folan, Thomas M. Keating, Martin Burke
  • Patent number: 11730886
    Abstract: Junction assemblies for joining intravenous (IV) devices to tubing are provided. A junction assembly includes a component connector and a shaped memory polymer (SMP) member formed of a shape changing material. The junction assembly allows movement of the tube along the component connector when the SMP member is in an expanded state and the junction assembly retains the tube securely against the component connector when the SMP member is in a contracted state. The shape changing material changes to one of the expanded state and the contracted state upon being subjected to an external stimuli. Methods of assembling junction assemblies are also provided.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: August 22, 2023
    Assignee: CAREFUSION 303, INC.
    Inventors: Wantjinarjo Suwito, Zehra Sevinc
  • Patent number: 11723799
    Abstract: Disclosed are devices and methods for delivering a sheet of tissue into the eye in such a way that damage to the tissue is minimized, damage to the eye during insertion and manipulation of the tissue is minimized, and the tissue is released and delivered in a precise and controlled fashion.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: August 15, 2023
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventor: Arvydas Maminishkis
  • Patent number: 11596532
    Abstract: A stent is disclosed that has an elongated body composed of a bioabsorbable polymer having a proximal end, a distal end, two open spiral channels formed on the exterior surface of the body to provide fluid communication between the proximal end and the distal end. The stent also has a central lumen open at the proximal and distal ends of the stent for the passage of a guide wire. A method for using the stent and a kit containing the stent are also disclosed.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: March 7, 2023
    Assignee: Q3 MEDICAL DEVICES LIMITED
    Inventor: Eric K. Mangiardi
  • Patent number: 11583666
    Abstract: A disposable device for treating a condition of a ureter or kidney having a cylindrical body about 1-2 mm in diameter by about 5 to 10 mm in length and having a top and bottom end. The body is made of absorbent material that expands upon contact with pharmaceutical agent and bodily fluids and includes a string connected to the bottom end of the body for removing the device. The device can be used to treat a condition of the ureter or kidney by inserting into the ureter or kidney, delivering a pharmaceutical agent, and removing the device after it has been impregnated with fluid. The device can be included in a kit with an insertion device and/or appropriate pharmaceutical agents.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: February 21, 2023
    Inventor: David Hesse
  • Patent number: 11564820
    Abstract: The embodiments disclosed herein relate to a ureteral stent having two stent bodies and a tether. The stent can minimize or prevent migration of the device out of the bladder of the patient while also reducing patient discomfort associated with such stents.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: January 31, 2023
    Assignee: The Regents of the University of California
    Inventors: Ryan Hsi, Marshall Stoller
  • Patent number: 11559304
    Abstract: A surgical instrument comprising a first jaw, a second jaw rotatable relative to the first jaw, and a closure system for closing the second jaw is disclosed. The closure system comprises a multi-stage closure system. In at least one instance, the closure system comprises a first closure member which closes the second jaw quickly, but with low force, and a second closure member which closes the second jaw more slowly, but with a higher force.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: January 24, 2023
    Assignee: Cilag GmbH International
    Inventors: Chad P. Boudreaux, Frederick E. Shelton, IV, Chester O. Baxter, III, Michael J. Stokes, Jason L. Harris
  • Patent number: 11559672
    Abstract: Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: January 24, 2023
    Assignee: NXT Biomedical, LLC
    Inventors: Glen Rabito, Joseph Passman, Robert C. Taft, Stanton J. Rowe, Robert S. Schwartz, Alexander Siegel
  • Patent number: 11523938
    Abstract: Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with a suprachoroidal space of the eye. The implant can drain fluid from an anterior chamber of the eye to a physiologic outflow path of the eye, such as, the suprachoroidal space or other portion of the uveoscleral outflow path. The delivery or inserter devices or systems can be used in conjunction with other ocular surgery, for example, but not limited to, cataract surgery through a preformed corneal incision, or independently with the inserter configured to make a corneal incision. The implant can be preloaded with or within the inserter to advantageously provide a sterile, easy-to-use package for use by an operator.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: December 13, 2022
    Assignee: GLAUKOS CORPORATION
    Inventors: Gary Rangel-Friedman, David S. Haffner
  • Patent number: 11523940
    Abstract: Glaucoma treatment systems are disclosed. In various example, the glaucoma treatment systems include a body and a fluid conduit configured to facilitate an evacuation of fluid, such as aqueous humor, from a fluid-filled body cavity, such as an anterior chamber of an eye. In some examples, the fluid conduit is soft and compliant, and the glaucoma treatment system includes one or more stiffening members coupled with the fluid conduit to temporarily stiffen the fluid conduit and help aid in the delivery of the glaucoma treatment device. In some examples, the stiffening members are removable from the fluid conduit after the glaucoma treatment system has been implanted.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: December 13, 2022
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Peter J. Roeber, Jeffrey C. Towler
  • Patent number: 11517721
    Abstract: In general, medical sheath systems that include a curved support sheath are described. In one embodiment, the support sheath includes a curved tube includes a distal portion fixed in an orientation perpendicular to the proximal end during advancement of an interventional tool through the support sheath.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: December 6, 2022
    Assignee: Radux Devices, LLC
    Inventor: Gregory Gordon
  • Patent number: 11484421
    Abstract: An adjustable length medical device, such as a drainage stent, and delivery device for placing within the body, having an elongate tube and retention members at each end portion for anchoring the device in the body. The proximal portion of the device including the proximal retention member may be segmented in incremental portions so that the length of the device can be adjusted for placement.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: November 1, 2022
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Caleb Caldwell
  • Patent number: 11478249
    Abstract: A method may include positioning a first device within an internal carotid artery of a subject and impeding antegrade blood flow in the internal carotid artery. Additionally, the method may include delivering a pharmaceutical agent through an external carotid artery for passage into an ophthalmic artery of the subject.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: October 25, 2022
    Assignee: J.D. Franco & Co., LLC
    Inventors: Robert Vidlund, Michael Calhoun
  • Patent number: 11471324
    Abstract: Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: October 18, 2022
    Assignee: SIGHT SCIENCES, INC.
    Inventors: David Y. Badawi, Daniel O'Keeffe, Paul Badawi
  • Patent number: 11464952
    Abstract: A shunt system used to treat excess cerebrospinal fluid (CSF) accumulation is described. In some embodiments, the system utilizes various mechanical, electrical, or electromechanical concepts designed to either clean a portion of the shunt system, or customize CSF drainage.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: October 11, 2022
    Assignee: MicroVention, Inc.
    Inventors: Wenmar Badbada, Nga Ting Wong, Heath Bowman, Matt Biggers, Joseph Rye, Jared Shimizu
  • Patent number: 11446476
    Abstract: The present disclosure discloses a nephrostomy tube and a nephrostomy tube with curved drainage. The nephrostomy tube with curved drainage includes a bending head, a balloon element, and an elongated main body integrally connected with each other, wherein the nephrostomy tube with curved drainage has an guiding channel adapted for a guiding member to penetrate through, wherein the bending head has a first inner channel and at least two drainage bending channels located on the outer side of the first inner channel, wherein the balloon element has an air chamber and a second inner channel, wherein the at least two drainage bending channels are communicated with the second inner channel, wherein the elongated main body has a third inner channel communicated with the second inner channel of the balloon element, wherein the first inner channel, the second inner channel and the third inner channel from the guiding channel.
    Type: Grant
    Filed: January 16, 2022
    Date of Patent: September 20, 2022
    Inventors: Yue Cheng, Zejun Yan, Junhui Jiang
  • Patent number: 11446485
    Abstract: Apparatus and associated methods relate to a lead that includes metallic traces sandwiched between layers of polymers to form a ribbon (e.g., similar to a flex circuit). In an illustrative example, areas on both ends of the traces may be exposed, forming stimulation electrodes on one end and electrical contacts on the other. The ribbon may be formed such that it fits down a small diameter needle. When the needle is removed, the formed ribbon may relax and engage the tissue providing a means of retention. The lead may advantageously: (1) be minimally invasive to implant, (2) be inexpensive, (3) stay in place a temporary/trial medical procedure setting, and (4) be easy to remove.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: September 20, 2022
    Assignee: NEXTERN INNOVATION, LLC
    Inventors: John Swoyer, Jonathan Lawson, Jesse Geroy
  • Patent number: 11426577
    Abstract: The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopathy are provided. For example, the present invention provides materials and methods for modulating glymphatic clearance (e.g., enhancing glymphatic clearance) of pathogenic proteins.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 30, 2022
    Assignees: Wisconsin Alumni Research Foundation, Mayo Foundation for Medical Education and Research
    Inventors: Justin Williams, Kip Ludwig, Erika Ross
  • Patent number: 11395764
    Abstract: The present invention provides for a deformable, insertable device for relieving intraocular pressure comprising a body portion composed of a biocompatible porous material with pores throughout to permit drainage of fluid from the anterior chamber to the scleral tissue without collapse of the anterior chamber. The invention also includes a method for inserting the device into the eye and for using ultrasound intraoperatively to determine the position of surgical tools and devices within the sclera. The invention also includes a device excising sclera in an eye to create a chamber for insertion of the insertable device into the eye.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: July 26, 2022
    Inventor: S. Gregory Smith
  • Patent number: 11389638
    Abstract: A hemodynamic flow assist device includes a miniature pump, a basket-like cage enclosing and supporting the pump, and a motor to drive the pump. The device is implanted and retrieved in a minimally invasive manner via percutaneous access to a patient's artery. The device has a first, collapsed configuration to assist in implantation and a second, expanded configuration once deployed and active. The device is deployed within a patient's aorta and is secured in place via a self-expanding cage which engages the inner wall of the aorta. The device includes a helical screw pump with self-expanding blades, sensors, and anchoring structures. Also disclosed is a retrieval device to remove the hemodynamic flow assist device once it is no longer needed by the patient and an arterial closure device to close the artery access point after implantation and removal of the hemodynamic flow assist device.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: July 19, 2022
    Assignee: Hridaya, Inc.
    Inventors: Sanjaya Khanal, Joseph Kaminski
  • Patent number: 11344438
    Abstract: A stent (100) comprising a stent wall (102), the stent wall (102) having a plurality of side holes (110) extending therethrough, each side hole (110) having an upstream end (116) and a downstream end (118). The stent wall (102) tapers in thickness in a direction towards the side hole (110) at the upstream (116) and/or downstream (118) end of at least one of the side holes (110). Also disclosed are methods for making side holes (110) in stents (100) by milling and making stents (100) having side holes (110) by injection moulding.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: May 31, 2022
    Assignee: UNIVERSITY OF SOUTHAMPTON
    Inventors: Ali Mosayyebi, Dario Carugo, Costantino Manes
  • Patent number: 11337838
    Abstract: An apparatus comprises a sleeve, a seal, and an anchor assembly. The sleeve is flexible and non-permeable and is configured to fit in a duodenum. The seal is positioned at the proximal end of the sleeve and is configured to seal the proximal end of the sleeve against the stomach mucosa, the pylorus, or the duodenum mucosa. The anchor assembly comprises a pair of atraumatic anchor ends and a resilient member positioned between the anchor ends. At least a portion of the resilient member extends along at least a portion of the length of the sleeve. The resilient member is configured to bias the anchor ends generally toward each other, to thereby substantially anchor the sleeve in the duodenum. The sleeve is configured to prevent chyme from contacting the mucosa of the duodenum; and to prevent enzymes excreted in the duodenum from mixing with chyme in the duodenum.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: May 24, 2022
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Jason L. Harris, Mark S. Zeiner, Adam R. Dunki-Jacobs, Justin W. Sherrill
  • Patent number: 11318041
    Abstract: An everting balloon system is disclosed that can be used for the placement of an IUD within the uterine cavity of a female patient. The everting balloon system with IUD can be used to access a uterine cavity at specific locations in the fundus. A one-handed IUD delivery system for placement with an everting catheter is disclosed. An IUD loading system for placement within an everting catheter is disclosed. The everting catheter with an IUD can simplify the process of IUD placement within the uterine cavity.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 3, 2022
    Assignee: CrossBay Medical, Inc.
    Inventors: Steven R. Bacich, Matthew Thomas Yurek, Jack Greelis, Piush Vidyarthi
  • Patent number: 11318043
    Abstract: An ocular implant configured for implantation into the eye of a subject comprising an elongate outer shell (54), an internal plug (210) including a hydrogel and a drug reservoir including a drug (62) wherein the drug is configured to pass through at least a portion of the internal plug to control elution of the drug through the outer shell. The implant is made of biodegradable materials.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: May 3, 2022
    Assignee: DOSE MEDICAL CORPORATION
    Inventors: Harold Alexander Heitzmann, David Steven Haffner, Kenneth Martin Curry, Thomas W. Burns
  • Patent number: 11305093
    Abstract: The invention relates to a cannula comprising a tip and an outlet, the cannula having a reduction in the internal diameter, which reduction is designed as a conically tapering tip the end of which has a length that is shorter than the internal diameter of the adjoining portion of the cannula.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: April 19, 2022
    Assignee: Xenios AG
    Inventor: Ivo Simundic
  • Patent number: 11291807
    Abstract: An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: April 5, 2022
    Assignee: V-Wave Ltd.
    Inventors: Neal Eigler, James Whiting, Nir Nae
  • Patent number: 11278708
    Abstract: Implantable shunt devices and methods for draining cerebrospinal fluid from a patient's subarachnoid space include a shunt having opposed first and second ends, the second end being constructed to penetrate a wall of a sigmoid, transverse, straight, or sagittal sinus of the patient, a one-way valve, a hollow passageway extending between the second end and the one-way valve such that cerebrospinal fluid can be drained through the second end and out through the valve, and a mechanism coupled to the shunt and configured to anchor the shunt at a desired location proximal to the subarachnoid space.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: March 22, 2022
    Assignee: Tufts Medical Center, Inc.
    Inventors: Carl Heilman, Adel M. Malek
  • Patent number: 11241231
    Abstract: An endovascular anastomotic connector and method of using the same. The endovascular anastomotic connector includes a vascular conduit and a supply conduit. The vascular conduit has proximal and distal ends that reside within a vascular structure. The supply conduit extends at an angle from the vascular conduit. The proximal end of the supply conduit is configured to be attached to an auxiliary device.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: February 8, 2022
    Assignee: CircuLite, Inc.
    Inventor: Robert C. Farnan
  • Patent number: 11224745
    Abstract: A cochlear implant device is disclosed, comprising an inductive antenna, a stimulation unit, an electrode array, and an energy harvesting apparatus. The inductive antenna is configured to receive energy to operate the cochlear implant and to receive signals for a stimulation of a cochlea via an electrode array comprising a plurality of electrodes. The stimulation unit is configured to process the signals received by the inductive antenna to be usable for the electrodes of the electrode array. The electrode array is configured to apply the signals processed by the stimulation unit to the cochlea for the stimulation thereof. The energy harvesting apparatus is connected to the stimulation unit or to the electrode array, and is configured to harvest energy based on at least one of thermal, biochemical, biophysical, and mechanical processes/phenomena pertaining to the cochlea, and is configured to provide harvested energy to the stimulation unit or the electrode array, respectively.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: January 18, 2022
    Assignee: OTICON MEDICAL A/S
    Inventors: Søren Kamaric Riis, Guillaume Tourrel, Bradford Backus
  • Patent number: 11207457
    Abstract: A shunt rivet for implantation between a first body space and a second body space in a patient, such as to treat chronic obstructive pulmonary disease.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: December 28, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Rodney A. Brenneman, J Christopher Flaherty, Brad Kellerman
  • Patent number: 11207211
    Abstract: A lacrimal drug delivery device includes a reservoir configured to hold a drug. The reservoir is moveable between a relaxed state and an expanded state. A connector is fluidly coupled to the reservoir and a lumen is formed in the connector wherein the drug is configured to flow from the reservoir to an delivery site through the lumen. A hydrogel is within the lumen and configured to absorb the drug from the reservoir and deliver the drug from the lumen at the delivery site. The hydrogel includes a first section which absorbs the drug at a first rate of absorption. A delivery guide is detachably coupled to the reservoir to deliver the reservoir into a lacrimal sac of a patient.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: December 28, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Andy Schieber, Linda Thai, Malik Kahook
  • Patent number: 11179542
    Abstract: An implantable prosthesis is provided for repairing a fistula, such as an anal fistula. The prosthesis or fistula repair device may include a body with a shape configured for placement in the fistula. The prosthesis may also include an anchor or base that is located at one or both ends of the body to facilitate anchoring the prosthesis in position. The prosthesis may include one or more channels to create one or more pathways for drainage and/or irrigation of the fistula. The channel may have a relatively uniform dimension along its length or a tapered shape that increases along its length. The prosthesis may have an adjustable length for accommodating fistula tracts of varying lengths. The prosthesis may include elongated body segments that provide a wicking or capillary function to facilitate drainage of the fistula tract.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: November 23, 2021
    Assignee: C.R. Bard, Inc.
    Inventors: Karen E. Kullas, Tami L. Rathbun