With Flow Control Means (e.g., Check Valves, Hydrocephalus Pumps, Etc.) Patents (Class 604/9)
  • Patent number: 10525239
    Abstract: The disclosure relates to a cerebrospinal fluid (CSF) shunt for treatment of hydrocephalus, comprising a valve having an inlet port and an outlet port, which ports are for draining CSF, and a control port for regulating the drainage of CSF through the valve according to a hydrostatic pressure provided to the control port, which hydrostatic pressure is dependent on the body position of the patient. The disclosure further relates to a method for treatment of hydrocephalus comprising regulating drainage of CSF based on a hydrostatic pressure that is dependent on the body position of the patient.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: January 7, 2020
    Inventors: Niclas Roxhed, Staffan Johansson, Göran Stemme, Anders Eklund, Jan Malm
  • Patent number: 10524958
    Abstract: An apparatus for reducing intraocular pressure is provided. A tube extends from an inlet end in fluid communication with an anterior chamber of the eye, to direct an aqueous humor flow from the anterior chamber to an outlet end in fluid communication with a cavity, defined by a housing, for receiving the aqueous humor. A proximal end of an elongate tubular member defining a longitudinally-extending channel is engaged with the housing such that the channel is in fluid communication with the cavity and such that a distal end of the tubular member is spaced apart from the housing, wherein the channel is configured to receive the aqueous humor from the cavity and to direct the aqueous humor through the distal end to a drainage site disposed distally to the anterior chamber and to the housing. An associated method is also provided.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 7, 2020
    Assignee: Alievio, Inc.
    Inventors: Lucinda Camras, Rolf Erik Ypma
  • Patent number: 10492948
    Abstract: A method of treating glaucoma in an eye utilizing an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer surface of the plate. An inflow end of the drainage tube tunnels through the sclera and cornea to the anterior chamber of the eye. The drainage tube collapses upon initial insertion within an incision in the sclera and cornea, or at a kink on the outside of the incision, but has sufficient resiliency to restore its patency over time. The effect is a flow restrictor that regulates outflow from the eye until a scar tissue bleb forms around the plate of the shunt. The plate desirably has a peripheral ridge and a large number of fenestrations, and a longer suturing tab extending from one side of the plate to enhance visibility and accessibility when suturing the shunt to the sclera.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: December 3, 2019
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventor: George Baerveldt
  • Patent number: 10485564
    Abstract: The invention relates to systems and methods to improve perfusion flow and pressure during endovascular intervention. In particular, the invention relates to catheters that enable both antegrade and retrograde flow through the catheter during a recanalization procedure and specifically at the step in a procedure where a clot is being withdrawn. Additionally, the invention provides systems for supplying fluids and fluid compositions to improve nutrition to ischemic brain.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: November 26, 2019
    Assignee: MG STROKE ANALYTICS INC.
    Inventor: Mayank Goyal
  • Patent number: 10463484
    Abstract: Embodiments of a prosthetic heart valve are disclosed. An implantable prosthetic valve can include an annular frame having an inflow end, an outflow end and a central longitudinal axis extending from the inflow end to the outflow end. The valve can include a valvular structure including two or more leaflets, each of the two or more leaflets having a leaflet inflow edge positioned at least partially outside of the frame and a leaflet outflow edge positioned within the frame, wherein at least a portion of each of the leaflet inflow edges is unsupported by the frame.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: November 5, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventor: Tamir S. Levi
  • Patent number: 10451451
    Abstract: A fluid monitoring assembly includes a conduit having a wall defining a lumen for carrying fluid. A sensor mount is integrally formed with the wall of the conduit and extends generally transverse with respect to a longitudinal axis of the conduit, the sensor mount including an aperture defining an inner surface extending to the lumen. The assembly includes a sensor configured to be removably secured within the sensor mount, the sensor having an elongate body terminating at one end thereof in a sensing portion, the elongate body having a male projection on a portion thereof and configured to rest within the inner surface of the sensor mount. The assembly further includes a housing having first and second portions connected to one another, the housing defining an interior portion configured to encapsulate the conduit, at least a portion of the elongate body of the sensor, and the sensor mount.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: October 22, 2019
    Assignee: ALPHINITY, LLC
    Inventors: Michael C. Gagne, Steven V. Cates, Dean Richards, Scott Bendon
  • Patent number: 10448953
    Abstract: Provided is a method of treating cardiac arrhythmia in a patient. The method comprises selecting a patient suffering from a cardiac arrhythmia and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. Systems and devices for creating a flow pathway are also provided.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: October 22, 2019
    Assignee: Rox Medical, Inc.
    Inventors: Rodney Brenneman, Peter Balmforth, J. Christopher Flaherty
  • Patent number: 10420479
    Abstract: An intracranial pressure monitoring device includes a housing defining a first internal chamber, a plurality of strain gauges disposed on an inner surface of a diaphragm defined by a wall of the first internal chamber, a device for generating orientation signals, and circuitry coupled to the plurality of strain gauges and to the device. The circuitry is configured to generate intracranial pressure data from signals received from the plurality of strain gauges, generate orientation data based on the orientation signals received from the device, and store the intracranial pressure data and the orientation data in a computer readable storage such that the intracranial pressure data and orientation data are associated with each other.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: September 24, 2019
    Assignee: Branchpoint Technologies, Inc.
    Inventors: Kevin Hughes, Alexander Strachan
  • Patent number: 10420665
    Abstract: A gastrointestinal device for treating obesity includes a three-dimensional porous structure configurable between a compressed pre-deployment configuration to facilitate delivery and an expanded post-deployment configuration. The porous structure includes a first opening at its proximal end and a larger second opening at its distal end. The porous structure also includes a sleeve coupled to its distal end. Optionally, the device further includes a suture at the proximal end of the wire mesh structure to facilitate retrieval and an anti-migration component positioned at the junction of the porous structure with the sleeve. The porous structure is deployed in a patient's stomach such that the anti-migration component sits proximal to the patient's pylorus and prevents migration of the entirety of the device into and through the pylorus. The sleeve extends through the pylorus, into the duodenum and ends in the duodenum or jejunum.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: September 24, 2019
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Virender K. Sharma, Raghuveer Basude
  • Patent number: 10413710
    Abstract: Drainage systems for excess body fluids and associated methods are disclosed herein. A drainage system in accordance with an embodiment of the present technology can include, for example, a drainage catheter, a first reference line, a second reference line, and a pressure sensor assembly. The catheter can include a flexible interface member and an inlet can be placed in fluid communication with a site of excess body fluid within a patient. A first flexible region of the first reference line can be in pressure communication with the flexible interface member, and a second flexible region of the second reference line can be in pressure communication with the surrounding atmosphere. The pressure sensor assembly can be spaced apart from the flexible regions, and measure the pressures of the first and second reference lines. This information can be used to determine the pressure at the site of excess body fluid.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: September 17, 2019
    Assignee: University of Washington
    Inventors: Barry Lutz, Samuel R. Browd, Thomas Clement, Brian Cran, Joel Relethford
  • Patent number: 10398594
    Abstract: The present invention provides methods and devices for delivering an active agent into the eye of a subject. In one aspect, for example, the present invention provides an ocular drug delivery device including a housing configured to couple to the eye of the subject and a corneal seal coupled to the housing and positioned in the housing to encircle the cornea during use to form a corneal region, where the housing extends outward from the corneal seal to form a scleral region, and where the scleral region being positioned over the eye's sclera during use. The device further includes an active agent reservoir coupled to the housing and positioned to release active agent into the scleral region and a pressure regulator coupled to the housing that is operable to introduce negative pressure between the housing and the eye. Thus the corneal seal is operable to fluidically isolate the corneal region from the scleral region in response to the negative pressure.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: September 3, 2019
    Assignee: Aciont, Inc.
    Inventor: John W. Higuchi
  • Patent number: 10369047
    Abstract: Drainage of aqueous from the anterior chamber of the eye can be facilitated by a malleable hollow clip or staple that can be formed to attach to ophthalmic tissue and provide intra-luminal flow of aqueous through the clip. In addition, the clip can be adjusted to modulate the outflow rate of aqueous, both during the initial surgical procedure as well as on a post-procedure basis. Furthermore, an instrument is described in which the forceps of the clip delivery device reside inside the lumen of hollow clip during deployment and manipulation. Features of an instrument are designed to secure the clip to the delivery forceps and prevent tissue blockage of the clip lumens. The clips may be color-matched to the underlying tissue for the purpose of camouflage and may carry pharmaceuticals.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: August 6, 2019
    Assignee: O3 Optix LLC
    Inventors: Kenneth A. Peartree, Tim Buckley, Aaron Feustel
  • Patent number: 10321912
    Abstract: Medical device including an artificial contractile structure including at least one contractile element adapted to contract a hollow body organ, in such a way that the contractile element is adapted to be in a resting position or in an activated position, the activated position being defined with the contractile element constricting the hollow body organ and the resting position being defined with said contractile element not constricting the hollow body organ. The medical device can include a tensioning device adapted to apply a force so as to tighten the contractile element around said hollow body organ. The tensioning device can be arranged to cause the contractile element to apply a substantially uniform occlusive pressure of at most 8N/cm2, along the circumference of the contact area between the contractile element and the hollow body organ when the contractile element is in its activated position.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: June 18, 2019
    Assignees: MyoPowers Medical Technologies SA, MyoPowers Medical Technologies France SAS
    Inventors: Marco Wieland, Claude Clement, Martin Horst
  • Patent number: 10322268
    Abstract: Embodiments for a cerebrospinal fluid flow detector for detecting the flow of cerebrospinal fluid are disclosed. In some embodiments, the cerebrospinal fluid flow detector includes a casing with a rotatable wheel having a plurality of radially extending arms disposed therein. The rotatable wheel is in communication with a channel having a distal end in communication with an inlet port and a proximal end in communication with an outlet port such that the flow of cerebrospinal fluid through the channel causes the rotatable wheel to rotate. In some embodiments, each radially extending arm includes at least one radiopaque marker in which movement of the rotatable wheel caused by fluid flow through the channel allows an X-ray imaging apparatus to detect the difference in position of a respective radiopaque marker at multiple times caused by rotation of the rotatable wheel.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: June 18, 2019
    Assignee: DIGNITY HEALTH
    Inventor: John Paul Sheehy
  • Patent number: 10300183
    Abstract: The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: May 28, 2019
    Assignee: LifeCell Corporation
    Inventors: Sangwook Park, Jerome Connor, Aaron Barere
  • Patent number: 10286131
    Abstract: Apparatus and methods are described, including apparatus (20) for implanting in a heart of a human subject. The apparatus includes an interatrial anchor (22) shaped to define an opening (26) having a diameter of 4-8 mm, and a bag (24) in fluid communication with the opening of the anchor. The apparatus is shaped to fit within a right atrium of the heart of the subject, and has a capacity of between 4 and 20 cm3. Other applications are also described.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: May 14, 2019
    Assignee: RAINBOW MEDICAL LTD.
    Inventors: Zev Sohn, Yossi Gross
  • Patent number: 10285853
    Abstract: Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with a suprachoroidal space of the eye. The implant can drain fluid from an anterior chamber of the eye to a physiologic outflow path of the eye, such as, the suprachoroidal space or other portion of the uveoscleral outflow path. The delivery or inserter devices or systems can be used in conjunction with other ocular surgery, for example, but not limited to, cataract surgery-through a preformed corneal incision, or independently with the inserter configured to make a corneal incision. The implant can be preloaded with or within the inserter to advantageously provide a sterile, easy-to-use package for use by an operator.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 14, 2019
    Assignee: Glaukos Corporation
    Inventors: Gary Rangel-Friedman, David S. Haffner
  • Patent number: 10258800
    Abstract: An antenna assembly includes: an antenna including: a metal signal layer having a radiating surface; and a feed port; and a waveguide surrounding the antenna and configured to guide electromagnetic energy transmitted from the radiating surface in a direction away from the antenna; and a controller module connected to the feed port and configured to drive the antenna to transmit electromagnetic energy from the radiating surface; wherein the antenna, waveguide, and controller module are configured such that, when the controller module drives the antenna, the transmitted electromagnetic energy matches a reception characteristic of an implantable device and is sufficient for the implantable device to create one or more electrical pulses of sufficient amplitude to stimulate neural tissue of a patient, solely using electromagnetic energy received from the antenna, when the implantable device is located at least 10 centimeters away from the antenna.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: April 16, 2019
    Assignee: Stimwave Technologies Incorporated
    Inventors: Laura Tyler Perryman, Richard LeBaron, Andrej Simeunovic
  • Patent number: 10251740
    Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: April 9, 2019
    Assignee: V-Wave Ltd.
    Inventors: Neal Eigler, Lior Rosen, Werner Hafelfinger, Erez Rozenfeld, Tamir Ben-David, Nir Nae, Menashe Yacoby, Yaacov Nitzan
  • Patent number: 10238536
    Abstract: A glaucoma drainage device regulator (GDDR) is disclosed which comprises a membrane and a lumen to regulate the flow of aqueous in conjunction with different ocular (e.g., glaucoma) filtering procedures. In connection with aqueous shunting, the GDDR can be placed over the tip of a shunt tube in the anterior chamber, either at the time of initial surgery or also in devices which have been previously implanted. In connection with trabeculectomy, the GDDR can comprise a flange for seating the GDDR at the sclerostomy in trabeculectomy surgery.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: March 26, 2019
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Jeffrey Olson, Ramanath Bhandari
  • Patent number: 10238535
    Abstract: Lacrimal implants and related methods providing secure, wedgable retention within a lacrimal punctum and associated canaliculus of an eye are disclosed. The lacrimal implants can comprise an implant body configured for at least partial insertion through the lacrimal punctum and into the canaliculus. The implant body can include first and second portions, and can extend from a proximal end of the first portion defining a longitudinal proximal axis to a distal end of the second portion defining a longitudinal distal axis. The implant body can be configured such that, when implanted using an integral dilator, an angled intersection exists between the proximal and distal axes. In this way, at least a portion of the implant body can be biased against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature, thereby retaining an implanted position of the lacrimal implant using anatomical structures.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: March 26, 2019
    Assignee: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, Charles Richard Kjellbotn
  • Patent number: 10219898
    Abstract: The invention discloses an artificial valve (10, 20, 30, 50) for implantation in a mammal body, in or adjacent to a mammal blood vessel, comprising a casing (12, 37, 61) and a closing mechanism, with at least part of said closing mechanism being a first moving part (11; 21, 22; 31, 32, 33; 51) adapted to make movements relative to said casing (12, 37, 61), said movements being to assume an open and a closed position for opening and closing, respectively, the blood flow through said blood vessel, as well as to positions in between said open and closed positions. In the valve of the invention, the closing mechanism is adapted to be powered in its movements to the closed position, with the powering being at least in part by means of a power mechanism (76, 83) external to the blood vessel.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: March 5, 2019
    Inventor: Peter Forsell
  • Patent number: 10215597
    Abstract: A fluid monitoring assembly includes a conduit having a wall defining a lumen for carrying fluid. A sensor mount is integrally formed with the wall of the conduit and extends generally transverse with respect to a longitudinal axis of the conduit, the sensor mount including an aperture defining an inner surface extending to the lumen. The assembly includes a sensor configured to be removably secured within the sensor mount, the sensor having an elongate body terminating at one end thereof in a sensing portion, the elongate body having a male projection on a portion thereof and configured to rest within the inner surface of the sensor mount. The assembly further includes a housing having first and second portions connected to one another, the housing defining an interior portion configured to encapsulate the conduit, at least a portion of the elongate body of the sensor, and the sensor mount.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: February 26, 2019
    Assignee: ALPHINITY, LLC
    Inventors: Michael C. Gagne, Steven V. Cates, Dean Richards, Scott Bendon
  • Patent number: 10206774
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: February 19, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 10197171
    Abstract: The present disclosure provides a method and apparatus for draining. The apparatus includes a body, the body having a first compartment adjacent to a second compartment, the first compartment having an inlet port fluidly connected to an outlet port, the inlet port defining a needle seat within the first compartment, a first rod hole for operation with a second rod hole in the second compartment, and a plurality of venting holes, the second compartment having a plurality of spaced notches along. The apparatus further includes a setting rod, the setting rod having a shaft and a sealing head, the shaft sized to be slideably maintained in the first rod hole and the second rod hole, the sealing head slideably attached to an end of the shaft and sized to obstruct fluid flow from the inlet port at the needle seat.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: February 5, 2019
    Assignee: Infinivation Biomedical LLC
    Inventor: Thomas J. Pennell
  • Patent number: 10076643
    Abstract: A gravitational pressure regulating valve to regulate fluid flow of a patient, including a fluid chamber having an inlet port to receive a bodily fluid and an outlet port to discharge received bodily fluid, the fluid chamber including a first chamber configured to capture a non-buoyant member therein and to guide the non-buoyant member along a longitudinal axis of the first chamber to facilitate bi-directional reciprocating movement of the non-buoyant member to and from the inlet port, and a second chamber configured to capture one or more buoyant members therein such that when the second chamber is filled with bodily fluid, at least one of the buoyant members applies a resolved buoyant pressure from a buoyant force of the one or more buoyant members in opposition to an inlet pressure of fluid at the inlet port.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: September 18, 2018
    Assignee: Arkis Biosciences Inc.
    Inventors: Chad Seaver, Chris Arnott, James Alexander Killeffer
  • Patent number: 10052463
    Abstract: A shunt device for directing fluid from a human head, and methods thereof are provided herein. The device can be mounted at a skull and include a first catheter that extends into a portion of the head such as a lateral ventricle. The first catheter can covey fluid through, and past a valve to a shunt body. The shunt body can include openings, allowing the fluid to reenter the head, for example at the subarachnoid space. The shunt body can also include other openings that can be associated with a second catheter. Fluid can thus also be conveyed out of the body or to a subgaleal pocket.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: August 21, 2018
    Assignee: Koucky & Volkodav LLC
    Inventors: Oleg Volkodav, Irina Koucky
  • Patent number: 9956106
    Abstract: A gastrointestinal device and methods of manufacturing said gastrointestinal device are described and include a flexible tubular structure including a layered wall, the flexible tubular structure including a plurality of at least one type of commensal microbe encased in the layered wall, the layered wall configured to allow an interaction between the plurality of the at least one type of commensal microbe and an ingested product within the flexible tubular structure, and a proximal end and a distal end, the proximal end and the distal end forming a flow conduit through the flexible tubular structure; and at least one anchor structure including one or more gastric wall-engaging components configured to engage a wall of the gastrointestinal tract of the subject.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: May 1, 2018
    Assignee: Elwha LLC
    Inventors: Mahalaxmi Gita Bangera, William David Duncan, Roderick A. Hyde, Wayne R. Kindsvogel, Elizabeth A. Sweeney
  • Patent number: 9949856
    Abstract: The present disclosure provides an inflatable weight control device that is implanted long-term with an endoscope in obese and bariatric human patients to promote early and prolonged satiety. The device includes a flexible, inflatable member coupled to a valve body assembly and an elongated durable module residing within the flexible member. The flexible member is selectively inflated to form two bulbs with a central passageway extending through the bulbs and the valve body assembly. Once the bulbs are inflated, the device is retained within the patient's pyloric valve to form a gastric outlet obstruction wherein chyme accumulates and then is directed through the central passageway to reach the patient's duodenum. Due to its unique configuration, the implanted device reduces gastric outflow which results in early and prolonged satiety when the patient consumes normal-sized meals or food portions, thereby reducing food consumption and increasing the patient's weight loss.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: April 24, 2018
    Assignee: AGT, Inc.
    Inventors: Gary Annunziata, Timothy Stippick
  • Patent number: 9949855
    Abstract: A gastrointestinal device and methods of manufacturing said gastrointestinal device are described and include a flexible tubular structure including a layered wall, the flexible tubular structure including at least one microbe-promoting agent encased in the layered wall, the microbe-promoting agent configured to promote at least one of attraction, colonization, and growth of at least one type of commensal microbe, and a proximal end and a distal end, the proximal end and the distal end forming a flow conduit through the flexible tubular structure; and at least one anchor structure including one or more gastric wall-engaging components configured to engage a wall of the gastrointestinal tract of the subject.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: April 24, 2018
    Assignee: Elwha LLC
    Inventors: Mahalaxmi Gita Bangera, William David Duncan, Roderick A. Hyde, Wayne R. Kindsvogel, Elizabeth A. Sweeney
  • Patent number: 9895547
    Abstract: The present disclosure provides advantageous optical conduit assemblies (e.g., biocompatible and implantable optical conduit assemblies), and related methods of use. More particularly, the present disclosure provides advantageous optical conduit assemblies (e.g., polydimethylsiloxane (“PDMS”)-based optical conduit assemblies) configured to power implantable devices (e.g., neural micro-stimulators or deep brain stimulators or the like) or to be used in optogenetic stimulation. In general, the exemplary optical conduit assemblies can be used for applications where energy needs to be transmitted to deep locations inside the body or brain without using electrical wires. Therefore, implantable devices that need to be powered (e.g., neural prosthetics) can be powered from an external light source using an optical conduit and an optical-to-electrical converter (e.g., a photodiode) attached to the end of the optical conduit on the inside.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: February 20, 2018
    Assignee: New Jersey Institute of Technology
    Inventors: Mesut Sahin, Ali Ersen
  • Patent number: 9861731
    Abstract: Endoluminal devices are provided for the treatment of heart failure which include a central body adapted to permit the passage of interatrial blood, at least one anchor attached to the central body adapted to keep the endoluminal device in position within a defect present in the atrial septum of a patient's heart, and at least one control element engaged with the central body in a rotating manner. The rotation of the control element in relation to the central body creates a two-way flow of interatrial blood which allows the reduction of high pressure in the right side and in the left side of the heart.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: January 9, 2018
    Inventor: Corrado Tamburino
  • Patent number: 9821100
    Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: November 21, 2017
    Assignee: Abiomed, Inc.
    Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
  • Patent number: 9808373
    Abstract: Implanting an intraocular shunt into an eye can involve creating an opening in the cornea and positioning a shunt in the anterior chamber of the eye such that the shunt terminates between layers of Tenon's capsule, thereby facilitating fluid flow out of the anterior chamber into a space between the layers of Tenon's capsule.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: November 7, 2017
    Assignee: AqueSys, Inc.
    Inventors: Christopher Horvath, Laszlo O. Romoda, Richard A. Lewis
  • Patent number: 9744338
    Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.
    Type: Grant
    Filed: April 18, 2015
    Date of Patent: August 29, 2017
    Assignee: Alcyone Lifesciences, Inc.
    Inventors: Andrew East, Morgan Brophy, Deep Arjun Singh, P J Anand, Robert Degon, Timothy Fallon, Allison Waller, Matthew Attar
  • Patent number: 9681948
    Abstract: A medical implant including an anchor portion including a plurality of arms adapted to engage an internal tissue wall of a body from two opposite faces, wherein the anchor portion is configured such that at least one of the arms does not have an entirely overlapping arm on the other side of the wall and an opening portion adapted to define an opening for blood flow through the internal tissue wall, when the anchor portion engages the wall.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: June 20, 2017
    Assignee: V-Wave Ltd.
    Inventors: Tamir Levi, Meir Rosenberg, Ori Ben-Amotz, Yoram Rozy, Eyal Benbenisti, Roey Shafrir, Doron Kopelman, Itshak Cohen, Tamar Harel
  • Patent number: 9655778
    Abstract: A position sensitive implant is described which comprises a flow channel which is provided with a value which will automatically adjust flow rate through the flow channel depending on whether the flow channel is generally vertical or generally horizontal. The implant may be a shunt used to treat glaucoma.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: May 23, 2017
    Inventor: Thomas D. Tyler
  • Patent number: 9655777
    Abstract: Systems and methods for treating an ocular condition includes a heating chamber comprising a material expandable when heated and comprising a flow passage having an inlet and an outlet. A heating element is arranged and disposed to introduce heat in the heating chamber. A flexible diaphragm separates the heating chamber from the flow passage, and is moveable between a first position and a second position to change a volume of one of the pump chamber and flow passages in response to a temperature change in the heating chamber.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: May 23, 2017
    Assignee: Novartis AG
    Inventor: Michael LeRoy Gelvin
  • Patent number: 9649185
    Abstract: An adjunct for a gastrointestinal device and a system including said adjunct are described herein and include a substrate configured to attach to a gastrointestinal device, the substrate including a first surface and a second surface, and a plurality of at least one type of commensal microbe associated with at least a portion of at least one of the first surface and the second surface of the substrate.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: May 16, 2017
    Assignee: Elwha LLC
    Inventors: Mahalaxmi Gita Bangera, William David Duncan, Roderick A. Hyde, Wayne R. Kindsvogel, Elizabeth A. Sweeney
  • Patent number: 9603742
    Abstract: A system for implantation in an eye of a patient includes a flow device sized for implantation into the eye of the patient. The flow device includes a fluid flow passageway and a flow system. The flow system may include a regulator having a magnetic element, and may be displaceable in the fluid flow passageway to affect flow through the fluid flow passageway. The system may also include a control device physically separate from the flow device and configured to be disposed outside the eye, the control device comprising an actuator magnetic field generator configured to act on the magnetic element to adjust the regulator in the flow system to selectively adjust flow through the flow device in response to changes in intraocular pressure.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 28, 2017
    Assignee: Novartis AG
    Inventors: Robert Sanchez, Casey Lind
  • Patent number: 9592151
    Abstract: Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space of the eye. The implant can drain fluid from an anterior chamber of the eye to a physiologic outflow path of the eye, such as, the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space. Alternatively, or in addition, the implant can elute a drug or therapeutic agent. The delivery or inserter devices or systems can be used in conjunction with other ocular surgery, for example, but not limited to, cataract surgery through a preformed corneal incision, or independently with the inserter configured to make a corneal incision.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: March 14, 2017
    Assignee: GLAUKOS CORPORATION
    Inventors: Gary Rangel-Friedman, David S. Haffner
  • Patent number: 9572963
    Abstract: An embodiment of a system for shunting aqueous humor from an anterior chamber of an eye includes an implant having an elongated body made of biocompatible material and a delivery device. At least a portion of the elongated body is implantable between a sclera and a ciliary body while the elongated body resides entirely within the confines of the sclera and a cornea with the proximal end of the implant being configured to reside within an anterior chamber angle and a lumen extending from at least one inlet port of the implant, through at least a portion of the elongated body, to one or more outlet ports of the implant so as to drain fluid from the anterior chamber toward a choroid of the eye. The delivery device includes an elongated member with a curved distal end portion to deliver the implant using an ab interno procedure.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: February 21, 2017
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, Barbara A. Niksch, David Steven Haffner, Gregory T. Smedley, Richard A. Hill, Olav B. Bergheim
  • Patent number: 9572965
    Abstract: An adjustable hydrocephalus valve for pressure equalization of the cerebrospinal fluid in the cranium of a hydrocephalus patient. The valve is adjustable to change the opening and closing pressure of the valve. The valve housing has a cover portion that can be depressed to thereby disengage a locking device to permit adjustment of the valve. The cover portion bulges outwardly, but bulges inwardly when depressed. The cover portion snaps when moved between the outward bulge and the inward bulge to thereby generate an audio and/or visual signal indicating that the cover portion has been switched from the outward bulge to the inward bulge, and vice versa.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: February 21, 2017
    Assignee: C.MIETHKE GMBH & CO KG
    Inventor: Christoph Miethke
  • Patent number: 9561131
    Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: February 7, 2017
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib, Thomas W. Burns, Richard Lindstrom
  • Patent number: 9561068
    Abstract: Ablation catheters and systems include multiple inline chambers for containing and heating an ablative agent. The heating chamber includes one or more channels to increase the contact surface area of the ablative agent with the walls of the heating chamber to provide more efficient heating. Induction heating is used to heat a chamber and vaporize a fluid within by wrapping a coil about a ferromagnetic chamber and providing an alternating current to the coil. A magnetic field is created in the area surrounding the chamber which induces electric current flow in the chamber, heating the chamber and vaporizing the fluid inside. Positioning elements help maintain the device in the proper position with respect to the target tissue and also prevent the passage of ablative agent to normal tissues.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: February 7, 2017
    Inventors: Virender K. Sharma, Harry Jabs
  • Patent number: 9539081
    Abstract: An endovascular valve device for use in a vessel during a therapy procedure includes a catheter having at its distal end a valve. The valve is constructed of a braid of elongate first filaments coupled together at their proximal ends in a manner that the first filaments are movable relative to each other along their lengths. The first filaments have a spring bias that radially expands the valve. A filter is provided to the braid formed by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments. The lumen of the catheter is in communication with the center of the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: January 10, 2017
    Assignee: Surefire Medical, Inc.
    Inventors: James E. Chomas, Leonard Pinchuk, John Martin, Aravind Arepally, Brett E. Naglreiter, Norman R. Weldon, Bryan M. Pinchuk
  • Patent number: 9517153
    Abstract: A liner support frame is configured to be positioned in a gastrointestinal tract of a human and to support a liner which inhibits nutrient absorption and anchor the liner in place in the gastrointestinal tract, the liner support frame includes a plurality of frame members connected to one another so that the liner support frame possesses a plurality of openings. The liner support frame includes a plurality of frame portions arranged axially and possessing different tapers.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: December 13, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Brian Roselauf, Jonathan Phan, Naoki Aramaki
  • Patent number: 9498379
    Abstract: Glaucoma drainage devices including vario-stable valves and associated systems and methods are disclosed. A glaucoma drainage device includes a drainage lumen and a valve system coupled to the drainage lumen to control the flow of fluid through the drainage lumen. The valve system includes an adjustable valve with a diaphragm that is in communication with the drainage lumen and is movable to occupy varying amounts of the drainage lumen. In some embodiments, the valve system is maintained in a desired position without the use of power such that power is only needed when changing a position of the adjustable valve.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 22, 2016
    Assignee: Alcon Research, Ltd.
    Inventors: Matthew A. Rickard, Leslie A. Field, Sebastian Bohm
  • Patent number: 9468737
    Abstract: A reperfusion system and method of perfusing a blood vessel using the reperfusion system are provided. The system includes an introducer sheath, a middle catheter extending through the introducer sheath, and a balloon microcatheter extending through the middle catheter. A connecting tube extends between a lumen of the introducer sheath and a valve at a proximal end of the microcatheter. A flow path is defined along a lumen of the introducer sheath, through the connecting tube, into the microcatheter, and out of a distal opening of the microcatheter. The balloon is disposed adjacent the exit point of the flow path to reduce reflux. Embolic material can be introduced into the microcatheter at the valve to exit at the same location as the blood flow.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: October 18, 2016
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Karol Lagodzki, Trevor Plassman
  • Patent number: 9468558
    Abstract: A method of treating glaucoma in an eye utilizing an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer surface of the plate. An inflow end of the drainage tube tunnels through the sclera and cornea to the anterior chamber of the eye. The drainage tube collapses upon initial insertion within an incision in the sclera and cornea, or at a kink on the outside of the incision, but has sufficient resiliency to restore its patency over time. The effect is a flow restrictor that regulates outflow from the eye until a scar tissue bleb forms around the plate of the shunt.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: October 18, 2016
    Assignee: Abbott Medical Optics Inc.
    Inventor: George Baerveldt