Abstract: An endoscope having a convex observation optical system at the distal end of an insertion portion is provided with an air supply/water supply nozzle for injecting a cleaning fluid toward the observation optical system. The air supply/water supply nozzle is provided with a plurality of outlets from which the fluid is emitted in directions not intersecting with each other.

Abstract: An arterial access device has an internal lumen and a proximal port, the arterial access device sized and shaped to be inserted directly into an arterial access site in the common carotid artery such that the lumen provides a passageway for an interventional device to be inserted via the proximal port into the carotid artery. The arterial access device has a distal portion that is configured to be inserted into an arterial pathway through the access site, and a proximal portion configured to extend outward from the access site when the distal portion is in the arterial pathway.

Abstract: Provided is an endoscopic treatment tool including: a sheath that has a longitudinal axis; a first operation wire and a second operation wire that are inserted through the sheath so as to be able to be moved forward and backward; a treatment part constituted by a first wire rod and a second wire rod that have lower bending rigidity than bending rigidity of the second operation wire; a first joint part inside which the second wire rod passes and that joins a distal-end section of the first operation wire and a proximal-end section of the first wire rod; and a second joint part that joins a distal-end section of the second operation wire and a proximal-end section of the second wire rod.

Abstract: To provide a basket-type treatment instrument for an endoscope such that wires constituting a basket are not liable to be damaged. A basket-type treatment instrument 1 for an endoscope having a basket part 40 formed such that a plurality of basket wires 41, 42 elastically expand or contract radially, wherein folded-back parts 41a, 42a formed by folding back substantially center portions of the basket wires 41, 42 are hooked to a substantially cylindrical first rib 6b fixed in a perpendicular direction to the cylinder axis of a distal tip 6, whereby the distal tip 6 retains the distal sides of the basket wires 41, 42 together.

Abstract: According to one aspect, a retrieval device may include a sheath having a distal end. The retrieval device may also include an end effector movable relative to the distal end of the sheath. The end effector may include first and second arms. The first arm may include a first opening at a distal portion of the first arm. The second arm may include a second opening at a distal portion of the second arm. The end effector may also include a third arm. The third arm may be slidably received in the first and second openings. A distal portion of the third arm may form at least part of a loop. The loop may extend through the first and second openings.

Abstract: Method, techniques, and apparatus of providing obscured feature detection. The disclosed embodiments provide an obscured feature detector to be placed on a surface to detect an obscured feature obscured by the surface, the obscured feature detector having a plurality of sensor plates arranged in an array. Measurements, via a sensing circuit, of capacitance readings sensed by the sensor plates in a plurality of regions are taken, each region corresponding to an area surrounding one or more of the at least three sensor plates. A comparison is made of the sensed capacitance readings in different regions using a controller coupled to the sensing circuit. The controller identifies an edge of the obscured feature and a centerline of the obscured feature, based on the comparison of the sensed capacitance readings. The controller activates an edge indicator to indicate proximity to the edge of the obscured feature and a centerline indicator to indicate the centerline of the obscured feature.

Abstract: Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

Abstract: Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion, inserting the device into the vascular lumen, positioning the distal portion in the vascular wall to at least partially surround the occlusion, and removing at least a portion of the surrounded occlusion from the lumen.

Abstract: A medical device includes a handle with a proximal arm and a distal arm. The proximal arm and the distal arm are pivotable via a joint. The medical device also includes a tube coupled to the distal arm and a drive wire. A distal portion of the drive wire includes an expandable end effector. A portion of the drive wire is positioned within the tube, and a different portion of the drive wire extends proximally of the distal arm and is coupled to the proximal arm.

Abstract: A surgical access device includes a housing, a tubular member extending from the housing, a valve disposed on the housing, and a tip member at a distal end of the tubular member. The housing includes a seal and the tubular member includes a plurality of lumens extending therethrough. The valve is fluidly coupled with a first lumen of the plurality of lumens and the tip member includes a first port that is aligned and fluidly coupled with the first lumen of the plurality of lumens. The first port is configured to direct a fluid towards a predetermined location.

Abstract: A method for forming a surgical snare, the method comprising: providing a plurality of filaments; braiding the plurality of filaments together so as to form a braided tubular construct comprising: a proximal tube having an open proximal end, an open distal end, and a proximal tube lumen extending there between; a distal tube having an open proximal end, an open distal end, and a distal tube lumen extending there between; and a loop region disposed between the distal end of the proximal tube and the proximal end of the distal tube, the loop region comprising at least one loop structure, the at least one loop structure comprising at least three of the plurality of filaments braided together; inserting the distal end of the distal tube into the open distal end of the proximal tube and into the proximal tube lumen such that (i) the distal tube is disposed in the proximal tube lumen such that the at least one loop structure extends distally of the distal end of the proximal tube in the form of at least one loop, a

Abstract: A catheter balloon includes a membrane having a proximal end and a distal end. A plurality of substrates are bonded about the membrane. The ability of a bond's ability to withstand repeated stresses during use may be improved by using a reinforcement or a stress relief, while also minimizing the overall thickness of the balloon proximate to its distal end. The reinforcement may comprise a portion of an unassembled membrane. Alternatively, the reinforcement may comprise an adhesive-margin tip. The stress relief may be a serpentine portion of a distal tail of a substrate.

Abstract: Methods, devices and systems for disabling and/or removing a mitral valve edge-to-edge repair device via minimally invasive, endovascular procedures. Additional procedures on a heart may sometimes become necessary after the installation of a mitral valve edge-to-edge repair device. To prepare for such additional procedures, the edge-to-edge repair device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart.

Abstract: A method of detecting a stuck basket condition involves retracting an endoscope within an anatomical cavity of a patient, the endoscope having a basket device disposed at least partially within a working channel thereof, determining that a force reading associated with at least one of the basket device and the endoscope exceeds a predetermined threshold, and determining that the basket device is in a stuck condition based at least in part on the determination that the force reading exceeds the predetermined threshold.

Abstract: A device may be used for capturing and retrieving vascular debris. The device may include: at least two segments radially expandable from a collapsed state to an expanded state, each of the at least two segments having (a) a waist including a radially largest region of the segment and (b) two longitudinal ends; at least one intermediate portion, each of the at least one intermediate portion including a pivot that connects adjacent segments, each pivot having a diameter less than a diameter of the waist; wherein each of the at least two segments includes at least two struts that extend longitudinally from a proximal end to a distal end of the segment, the at least two struts tapering from the waist radially inward toward a longitudinal axis of the device as the at least two struts approach an adjacent intermediate portion.

Abstract: A clot retrieval device that includes a proximal scaffolding section with a closed proximal end and an open distal end; an inner elongate member; and a distal scaffolding section with a closed proximal end and an open distal end element.

Abstract: Described herein are systems, devices, and methods for removing material from patient vasculature. In some embodiments, an aspiration device may include a sheath and a catheter slidably disposed within the sheath and defining a lumen. The catheter may include a distal end portion and an elongate portion, the distal end portion being disposable adjacent to a clot, the elongate portion being couplable to a vacuum source that is configured to apply a negative pressure to the lumen to draw the clot into the distal end portion. The distal end portion may include a plurality of sections, each of the plurality of sections having a different cut pattern.

Abstract: A guidewire holding device comprises a sheath including a lumen, a holder disposed at a distal end of the sheath and configured to be switchable between holding a guidewire and releasing the guidewire, a treatment tool inserted in the lumen to perform an intended treatment, and a wire connected to the treatment tool and configured to move the treatment tool between a first configuration and a second configuration. In the first configuration, the treatment tool is contained insider the lumen, and, in the second configuration, the treatment tool is protruded from the distal end of the sheath.

Abstract: A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns.

Abstract: A catheter system that is actuatable to a deployed state and includes a catheter body and a dilator positioned at least partially within the lumen of the catheter. A distal end of the dilator can be releasably connected to a distal tip of the catheter body. The dilator can be retractable to expand and invert the distal tip and form a funnel shape in the deployed state.

Abstract: A system for retrieving material or objects from a biological vessel is provided. the system includes an elongated braid structure configured for transitioning between collapsed and expanded states, the elongated braid structure surrounding a lumen having a distal opening when in the expanded state. The system further includes a closure wire positioned along a length of the elongated braid structure, the closure wire being actuatable to pull inward a distal portion of the elongated braid structure and thereby at least partially close the distal opening.

Abstract: A retrieval device may have a contracted state and an expanded state. The retrieval device may include a sheath and at least three support members. Each of the support members may have a first portion with a first cross-sectional shape and a second portion with a second cross-sectional shape different from the first cross-sectional shape. A proximal end fixed of each of the support members may be coupled to the sheath, and a distal end may be movable relative to the sheath. The retrieval device may further include at least three movable members movable relative to the support members. Each movable member may extend through a lumen of one support member of the at least three support members and through a lumen of a different support member of the at least three support members.

Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: A catheter system for imparting pressure to induce fractures at a treatment site within or adjacent a blood vessel wall includes a catheter, a fortified balloon inflation fluid and a first light guide. The catheter includes an elongate shaft and a balloon that is coupled to the elongate shaft. The balloon has a balloon wall and can expand to a first expanded configuration to anchor the catheter in position relative. The fortified balloon inflation fluid can expand the balloon to the first expanded configuration. The fortified balloon inflation fluid includes a base inflation fluid and a fortification component. The fortification component reduces a threshold for inducing plasma formation in the fortified balloon inflation fluid compared to the base inflation fluid. The fortification component can include at least one of carbon and iron. The first light guide is disposed along the elongate shaft and is positioned at least partially within the balloon.

Abstract: Funnel-trap type delivery and/or retrieval devices for Inferior Vena Cava (IVC) filters or other medical implants are described in which the devices comprise two layers of braid with an axially support member. The support member may be interposed between braid layers or set inside the braid layers but interposed between heatset features. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated herein.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Abstract: A reperfusion device for an occluded vessel. The device includes a framework of struts that form a porous body comprising a collapsed delivery configuration capable of being stored in a microcatheter and an expanded deployed configuration when delivered to an occlusion and distal of the microcatheter. The framework of struts is constructed from a material visible under fluoroscopy and capable of recovering its shape in the expanded deployed configuration once released from the collapsed delivery configuration in the microcatheter.

Abstract: A system including an outer member, an elongated column member extending distally from the outer member and an inner member positioned coaxial with the outer member and attached to the column member. The inner member extends distally of the outer member and has a distal portion. The catheter is positioned within an outer catheter, such as an aspiration catheter, which provides a reinforcement member over the column member to restrict movement of the column member such that when one of the inner member or outer member is moved with respect to the other, axial compression of the column member is restricted by the inner wall of the outer catheter causing the distal portion of the inner member to deflect laterally to thereby redirect the outer catheter.

Abstract: A specimen retrieval system for easier tissue removal during endoscopic surgery. The device includes a specimen tube with a main tube, and a mechanism for pulling and everting the distal end of the tube into the tube, or a side channel provided within the tube. The mechanism may include a tether fixed to the distal edge of the tube, or a grasper operable to grasp the distal edge of the tube.

Abstract: Methods and systems for spinal radio frequency neurotomy. Systems include needles capable of applying RF energy to target volumes within a patient. Such target volumes may contain target medial branch nerves along vertebrae or rami proximate the sacrum. Such procedures may be used to ablate or cauterize a portion of the targeted nerve, thus blocking the ability of the nerve to transmit signals to the central nervous system. Disclosed needles may be operable to asymmetrically, relative to a central longitudinal axis of the needle, apply RF energy. Such asymmetry facilitates procedures where a tip of the needle is placed proximate to anatomical structures for location verification. Then RF energy may be applied in a selectable direction relative to the needle tip to ablate volumes that include the targeted medial branch nerves or rami, thus denervating facet joints or the sacroiliac joint, respectively, to relieve pain in a patient.

Abstract: A catheter for use in a subject's vasculature includes a rotating and axially movable instrument. The instrument includes a rounded element at its distal end connected to a body having a spiral shape. The instrument is at least partially disposed in a lumen of the catheter and is configured for axial and rotational motion within the lumen between a proximal-most position and a distal-most position, where the body includes at least one edge configured to promote removal of a target substance from the body passageway upon contact with the target substance.

Abstract: A prosthetic implant delivery assembly includes a prosthetic implant including an expandable stent and a catheter for delivering the prosthetic implant. The expandable stent includes apices circumferentially-spaced apart relative to each other. At least some of the apices include an aperture disposed therein. The catheter includes arms disposed at an end of a shaft, and the arms are moveable between a radially compressed state and a radially expanded state via a sheath. The arms each include a hook portion for releasably engaging the apertures of the apices. The arms are configured to move from the radially compressed state to the radially expanded state when the plurality arms is exposed from within the sheath such that the hook portion disengages from the apices of the prosthetic implant and releases the expandable stent from the catheter.

Abstract: A medical device includes a handle with a proximal arm and a distal arm. The proximal arm and the distal arm are pivotable via a joint. The medical device also includes a tube coupled to the distal arm and a drive wire. A distal portion of the drive wire includes an expandable end effector. A portion of the drive wire is positioned within the tube, and a different portion of the drive wire extends proximally of the distal arm and is coupled to the proximal arm.

Abstract: A method of extracting a thrombus from a thrombus site in a cerebral artery of a patient by advancing a first catheter into an internal carotid artery of the patient; advancing a funnel catheter within the first catheter; moving the funnel catheter and the first catheter with respect to each other to place the funnel outside of the first catheter; expanding the funnel into contact with an inner wall of the internal carotid artery at or proximal to a distal end of a carotid siphon, thereby reducing blood flow past the funnel; advancing a clot-mobilizer distally through the first catheter toward the thrombus and beyond the carotid siphon; engaging thrombus material from the thrombus with the clot-mobilizer; moving the clot-mobilizer and thrombus material proximally at least partially into the funnel; applying suction to aspirate thrombus material; and moving the funnel, the clot-mobilizer and the thrombus material proximally within the vasculature.

Abstract: The present disclosure is directed to medical devices and methods of manufacturing medical devices, such as an ophthalmologic medical device.

Abstract: An obstruction removal device is configured to be inserted through a catheter and at least partially extended into a vasculature from a distal end of the catheter. The obstruction removal device includes: a base member configured to engage one or more guide stops at the distal end of the catheter; a tubular member coupled to the base member and configured to apply a suction force from the catheter to an obstruction to remove the obstruction from the vasculature; and an expandable member surrounding the tubular member. The expandable member is configured to transition from a contracted state to an expanded state after the expandable member is at least partially extended into the vasculature from the distal end of the catheter. The expandable member is further configured to at least partially surround the obstruction as the obstruction is being removed from the vasculature.

Abstract: A tissue specimen retrieval bag assembly includes a tissue specimen bag having an open proximal end and a closed distal end, the proximal end including a cuff defined therein and extending therearound. A flexible bag brim is disposed within the cuff and is transitionable between a first, collapsed configuration and a second, expanded configuration. The flexible bag brim includes a cross section configured to facilitate both furling the tissue specimen bag onto itself around the bag brim when the bag brim is disposed in the second, expanded configuration and securing the tissue specimen bag in a desired furled configuration. The flexible bag brim includes a plurality of scallops defined along an inner peripheral surface thereof configured to facilitate furling the tissue specimen bag onto itself.

Abstract: The present invention pertains to a thrombectomy device comprising a cylindrical proximal portion and one or more radiopaque segments. The cylindrical proximal portion forms a stent frame having an outer lattice network of an outer plurality of interconnecting segments. The outer plurality of interconnecting segments are configured to exert a radial force against an inner wall of a blood vessel. The radiopaque segment is formed from a plurality of radiopaque wires extending from the outer stent frame to a central axis of the thrombectomy device along a length of the stent frame. The radiopaque segment converges to a tip along with the central axis.

Abstract: A retrieval device may have a contracted state and an expanded state. The retrieval device may include a sheath and at least three support members. Each of the support members may have a first portion with a first cross-sectional shape and a second portion with a second cross-sectional shape different from the first cross-sectional shape. A proximal end fixed of each of the support members may be coupled to the sheath, and a distal end may be movable relative to the sheath. The retrieval device may further include at least three movable members movable relative to the support members. Each movable member may extend through a lumen of one support member of the at least three support members and through a lumen of a different support member of the at least three support members.

Abstract: A medical retrieval tool including a sheath; and a basket device connected to the sheath. The basket device includes a shaft and a basket located at a distal end of the shaft. The shaft is movably located in the sheath. The basket includes a first basket cage section and a second basket cage section. The first basket cage section is located in front of the second basket cage section. The basket is configured to be extended from a distal end of the sheath in a plurality of deployment modes including a first deployment mode where the first basket cage section is deployed in a first fully expanded shape and the second basket cage section is located in the sheath; and a second deployment mode where both the first basket cage section and the second basket cage section are deployed out of the distal end of the sheath.

Abstract: An endovascular medical system for use with a clot located in a target vessel. The system including a guidewire formed by a core wire. The guidewire extending in a longitudinal direction from a proximal end to an opposite atraumatic clot-circumventing configured distal end; and a lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire being defined transverse to the longitudinal direction of the guidewire. The atraumatic clot-circumventing configured distal end is designed to prevent injury to an inner wall of the target vessel and prohibit insertion of any portion of the guidewire into a perforator vessel.

Abstract: The present disclosure relates generally to the field of medical devices and methods to assist in the introduction of an instrument into a patient, and more particularly to medical devices for measuring and/or monitoring forces applied during introduction of an access sheath through a body lumen.

Abstract: Self-rolling mechanical apparatuses for removing material from a body lumen include a tractor tube portion that rolls and inverts over itself in a continuous motion, tractor-like, to draw material into the tractor tube, wherein the tractor tube rolls over itself without requiring any additional internal support at the distal-facing region of the tractor tube.

Abstract: Novel catheter with longitudinal expandable arid contractile elements which promote wave propagation. The tension-band characteristics of these elements enhance the “crawling” dynamics of the catheter. Tauglit is an aspiration catheter with three key components: an inner spring coil system, a soft pleated jacket with annuli that buckles under load and an outer proleg or leaf-spring that fattens the. diameter of the catheter. Smart features, robotics and AI may be on-boarded. As shown, subject catheters shall piston in a fixed environment (muscular structure such as an artery) and propagate forward akin to earthworm locomotion (Lumbricm terrestris).

Abstract: Provided is an intra-abdominal tissue retrieval bag. The bag has an inflated state and a deflated state. The bag is introduced into the abdomen in a deflated state through a small incision and placed underneath the specimen to be retrieved. The bag is defined by an inflatable defining circumferential ring at the opening and an inflatable collection sac. Both inflated using external pneumo source sequentially, the same that is used to maintain pneumoperitoneum during laparoscopic surgery. After insufflation, the specimen becomes fully contained and ready for retrieval after desufflation.

Abstract: A method of performing a medical procedure in a cerebral vessel of a patient including advancing a first catheter system towards an embolus within a cerebral blood vessel and a second catheter system towards the embolus through the first catheter, applying aspiration pressure through the lumen of the second catheter; anchoring a distal end of the second catheter onto the embolus via the aspiration pressure; applying a proximally-directed force on the second catheter; and advancing the first catheter over the second catheter towards the embolus while the distal end of the second catheter remains anchored onto the embolus; and automatically applying aspiration pressure within the first catheter upon the second catheter portion entering into the first catheter.

Abstract: A surgical device is disclosed for cutting tissue, including for performing a capsulotomy of a lens capsule of an eye. This device includes a reversibly collapsible cutting element for cutting a portion of a capsule membrane of the eye. The cutting element includes an outer layer, an inner layer, and a bottom layer that has a higher electrical resistance than the electrical resistance of the outer layer and the inner layer. The bottom layer is configured to conduct an electrical current between the outer layer and the inner layer, which causes a temperature increase in the bottom layer for cutting tissue.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.