By Means For Skin Graft Preparation (e.g., Dermatome) Patents (Class 606/132)
  • Patent number: 10285730
    Abstract: The invention relates to a dermatome, comprising: a blade holder for holding a blade, said blade holder comprising at least one guiding element for guiding an oscillating movement of a said blade, and at least one spacer spaced apart from said blade holder for defining a cutting gap between a said blade held by said blade holder and said spacer, wherein said at least one guiding element and said at least one spacer define a curved path. The invention further relates to a blade, suitable to be used in such a dermatome, as well as an assembly of such a dermatome and such a blade.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: May 14, 2019
    Assignee: Humeca Holding B.V.
    Inventor: Danielle Haagsma-Van der Kouwe
  • Patent number: 10245146
    Abstract: The present invention relates to a fenestrated bone graft and a method of preparing cortical bone in thin strips then fully demineralizing it to give it formed flexibility and then creating fenestrations in the cortical bone in a fashion similar to but not identical to skin grafts.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: April 2, 2019
    Assignee: Vivex Biomedical, Inc.
    Inventors: Harry Thomas Temple, Tracy Scott Anderson, Edgar S. Maldonado, Sonya A. Cooper
  • Patent number: 9993262
    Abstract: A skin graft mesher including a cutting roller and a guide roller rotatably mounted to a fixture. A skin graft may be advanced through the mesher between the rollers to form a pattern of perforations in the skin graft. The cutting roller includes cutting rings disposed on an axle and rotatable therewith. The cutting roller further includes a tissue clearing structure positioned between adjacent cutting rings with the axle extending through the tissue clearing structure and rotatable relative to the tissue clearing structure. The tissue clearing structure may clear tissue from between adjacent cutting rings during operation of the skin graft mesher. The tissue clearing structure may be eccentrically rotated about the axle between adjacent cutting rings with the tissue clearing structure extending radially outward beyond the outer diameter of the cutting ring around less than the entire outer circumference of the cutting ring.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: June 12, 2018
    Assignee: Zimmer Surgical, Inc.
    Inventor: Aleksandr Zolotov
  • Patent number: 9872677
    Abstract: A method for securing a flexible member may include forming a bore in a bone; inserting an anchor into the bore, the anchor including a passage and being coupled to a flexible member; slideably positioning a first load distributing member along the flexible member; inserting the first load distributing member into the bore such that the flexible member engages the first load distributing member; and applying tension to a portion of the flexible member to secure the anchor and load distributing member within the bone.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: January 23, 2018
    Assignee: Biomet C.V.
    Inventor: David Anderson
  • Patent number: 9814485
    Abstract: The present invention generally relates to devices and systems that utilize an inflatable bladder for generating, cutting, capturing, and/or transplanting one or more skin blisters. In some aspects, methods and devices in accordance with the present teachings can enable the harvesting of skin grafts from an increased variety of potential donor sites, such as areas of the body having uneven surfaces or a smaller radius of curvature (e.g., the arm) or large area donor sites where the creation of a vacuum may require a high power negative pressure source. In various aspects, systems, devices, and methods in accordance with the present teachings can also enable the efficient transplant of the grafts directly from the skin graft harvester to the recipient site without the transfer of the grafts generated by the harvester to another substrate prior to transplantation.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: November 14, 2017
    Assignee: KCI Licensing, Inc.
    Inventors: Benjamin A. Pratt, Christopher Brian Locke, Timothy Mark Robinson, Kevin Higley, Tab Randolph, T. Blane Sanders
  • Patent number: 9687268
    Abstract: A dermatome including a battery unit, a handle, and a head portion. The head portion includes guards capable of being adjusted to control the width and the depth of the cut without an interruption in the medical procedure.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: June 27, 2017
    Assignees: BioVentures, LLC, Arkansas Children's Research Institute
    Inventors: Gal Shafirstein, Anjay K. Khandelwal, James C. Walker
  • Patent number: 9539104
    Abstract: Implants for promoting bone growth and methods of using same, the implants including a perforated placental membrane sheet wrapped around an osteoconductive material composed of bone chips, bone granules, bone powders or combinations thereof, the osteoconductive material being configured for providing a scaffold upon which bone growth can occur. The placental membrane sheet acts to maintain the osteoconductive material in a cohesive, organized configuration within a site of a patient where bone growth is to be induced. The perforations in the placental membrane sheet create passageways in the exterior of the implant through which the osteoconductive material can communicate with adjacent bone surfaces which are to be fused.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: January 10, 2017
    Assignee: NuTech Spine, Inc.
    Inventors: Kenneth L. Horton, Gregory J. Yager, Howard P. Walthall, Jr.
  • Patent number: 9314271
    Abstract: A device for stretching skin having a plate-shaped main body and a tensioning element thereon. The tensioning element is rotatable about an axis of rotation, as a result of which a pulling thread affixed to the tensioning element is able to be wound up. A latching lock serves for fixing the rotatable tensioning element and includes a securing device for securing the latching lock against inadvertent release. The tensioning element is able to be moved in a direction of the axis of rotation against a force of a spring. The latching lock is able to be removed from a latching position, and return to the latching position as a result of a force from the spring. The securing is able to be actioned by a securing lever arranged on the rotatable tensioning element. A movement of the securing lever is able to action the tensioning element at the same time.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: April 19, 2016
    Assignee: Karl Storz GmbH & Co. KG
    Inventor: Martin Hahn
  • Patent number: 9173674
    Abstract: The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: November 3, 2015
    Assignee: MoMelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, Jeffrey Cerier, Andrew Ziegler
  • Patent number: 9055970
    Abstract: A skin graft mesher including a cutting roller and a guide roller rotatably mounted to a fixture. A skin graft may be advanced through the mesher between the rollers to form a pattern of perforations in the skin graft. The cutting roller includes cutting rings disposed on an axle and rotatable therewith. The cutting roller further includes a tissue clearing structure positioned between adjacent cutting rings with the axle extending through the tissue clearing structure and rotatable relative to the tissue clearing structure. The tissue clearing structure may clear tissue from between adjacent cutting rings during operation of the skin graft mesher. The tissue clearing structure may be eccentrically rotated about the axle between adjacent cutting rings with the tissue clearing structure extending radially outward beyond the outer diameter of the cutting ring around less than the entire outer circumference of the cutting ring.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: June 16, 2015
    Assignee: Zimmer Surgical, Inc.
    Inventor: Aleksandr Zolotov
  • Patent number: 9023831
    Abstract: A method of inhibiting the adverse effects of complement pathway, activation products in a subject comprising administering to the subject an amount of Dextran Sulfate effective to inhibit formation of alternative complement pathway activation product.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: May 5, 2015
    Assignee: Novelmed Therapeutics, Inc.
    Inventor: Rekha Bansal
  • Patent number: 8978234
    Abstract: The invention generally relates to methods for manufacturing components for use in a device for generating substantially planar micrografts. The methods of the invention provide for the manufacture of substantially uniform components for a cutter contained within the device, the cutter configured to cut a blister in order to produce a substantially planar graft.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: March 17, 2015
    Assignee: MoMelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, Jeffrey Cerier, Andrew Ziegler
  • Patent number: 8926631
    Abstract: The present invention generally relates to methods for preparing a skin graft without culturing or use of biologics.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: January 6, 2015
    Assignee: Momelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, M Josh Tolkoff, Andrew Ziegler
  • Patent number: 8926632
    Abstract: A dermatome having a handle and an attachment including a valve, where the valve may include a first bobbin at least partially defining a first flow path and a second flow path, a second bobbin at least partially defining a first flow path, an inlet port at least partially defined by the second bobbin and an outlet port at least partially defined by the first bobbin. The ports of the valve may open in response to an application of a mechanical act to the attachment and the ports may close in response to the absence or removal of the mechanical act.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: January 6, 2015
    Assignee: Zimmer Surgical, Inc.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20140343575
    Abstract: A device for tissue sampling and grafting has a handle (2), to whose end is fixed a coupling (4), a needle (6) fixed to the coupling. The device also includes a piston (3) connected to a pin (7). The piston and pin translate between an external condition (A), wherein a tip (73) of the in protrudes beyond the needle, and an internal condition (B), wherein the tip is retracted inside the needle. The device also includes a tip (5), having a truncated free end (51) that can be sharpened, constrained in a roto-translating way to the coupling, placed co-axially and externally to the needle and moved between a retracted condition (C) and an advanced condition.
    Type: Application
    Filed: November 22, 2012
    Publication date: November 20, 2014
    Inventors: Silvano ANDREANI, Ettore CASALE, Giorgio MAULLU
  • Publication number: 20140303648
    Abstract: Pixel array medical devices, systems and methods are described for skin grafting and skin resection procedures. The procedures involve applying a scalpet array to a target skin site. The scalpet array comprises scalpets positioned on an investing plate. Skin pixels are circumferentially incised at a target skin site by applying a load via the scalpet array onto subjacent skin surface that includes the target skin site. Incised skin pixels are captured on an adherent substrate, where the incised skin pixels are extruded through the scalpet array. Bases of incised skin pixels extruded through the scalpet array are then transected.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 9, 2014
    Inventor: Edward KNOWLTON
  • Publication number: 20140276957
    Abstract: Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: MUSCULOSKELETAL TRANSPLANT FOUNDATION
    Inventors: Michael Locarno, Bryan J. Choi, Mahn-Dan Ngo
  • Patent number: 8814881
    Abstract: A dermatome has a blade that generally defines a plane and a body generally defining a longitudinal axis. The body also that has at least one flat outer surface for engaging the tissue and an end portion that is configured to hold the blade so that the plane of the blade is generally parallel to the longitudinal axis and non-parallel to the flat outer surface at a predetermined angle.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: August 26, 2014
    Assignee: Zimmer Surgical, Inc.
    Inventor: David J. Boles
  • Publication number: 20140236180
    Abstract: A dermatome including a battery unit, a handle, and a head portion. The head portion includes guards capable of being adjusted to control the width and the depth of the cut without an interruption in the medical procedure.
    Type: Application
    Filed: February 19, 2014
    Publication date: August 21, 2014
    Inventors: Gal Shafirstein, Anjay K. Khandelwal, James C. Walker
  • Patent number: 8771291
    Abstract: Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for harvesting the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Exemplary embodiments of the invention provide a genetically modified dermal micro-organ expressing at least one recombinant gene product. Some embodiments of the invention provide methods and apparatuses for implanting a genetically modified DMO.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: July 8, 2014
    Assignee: Medgenics Medical Israel Ltd.
    Inventors: Stephen F. Bellomo, Alex Okun, Yaron Fuerst, David Shalhevet, Elisha Amir, Mordechay Bukhman
  • Publication number: 20140107668
    Abstract: A skin graft mesher including a cutting roller and a guide roller rotatably mounted to a fixture. A skin graft may be advanced through the mesher between the rollers to form a pattern of perforations in the skin graft. The cutting roller includes cutting rings disposed on an axle and rotatable therewith. The cutting roller further includes a tissue clearing structure positioned between adjacent cutting rings with the axle extending through the tissue clearing structure and rotatable relative to the tissue clearing structure. The tissue clearing structure may clear tissue from between adjacent cutting rings during operation of the skin graft mesher. The tissue clearing structure may be eccentrically rotated about the axle between adjacent cutting rings with the tissue clearing structure extending radially outward beyond the outer diameter of the cutting ring around less than the entire outer circumference of the cutting ring.
    Type: Application
    Filed: October 12, 2012
    Publication date: April 17, 2014
    Applicant: Zimmer Surgical, Inc.
    Inventor: Aleksandr Zolotov
  • Publication number: 20140074120
    Abstract: A combination (2290) of an annular rotary knife blade (2300) and blade housing assembly (2400) for a power operated dermatome (2000). The rotary knife blade includes an inner wall (2310) defining an interior region (2301) and including a lower tissue-directing surface (2370) adjacent a cutting edge (2360) and a radially recessed upper portion (2380). The blade housing assembly includes a blade housing (2410) having a first end (2412) and an axially spaced apart second end (2414) and an inner wall (2416) and a radially spaced apart outer wall (2418). The blade housing includes a blade housing cover (2450) extending from the inner wall into the blade interior region. The blade housing cover includes a shield (2470) extending along the recessed upper portion of the rotary knife blade inner wall and having an inner surface (2472) adjacent and continuing the lower tissue-directing surface of the rotary knife blade inner wall.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 13, 2014
    Applicant: Exsurco Medical, Inc.
    Inventors: Bernard J. Esarey, Jeffrey A. Whited
  • Publication number: 20140074118
    Abstract: A head assembly (200) for a power operated dermatome (100) including a frame body or housing (202) supporting a gear train (520), a blade housing assembly (400), an annular rotary knife blade (300) supported for rotation about an axis of rotation (R) by the blade housing assembly (400). The rotary knife blade (300) includes an inner wall (365) defining an interior region (301) and has a cutting edge (360) at one end (368) defining a cutting plane (CP). The head assembly (200) further includes a depth gauge assembly (600) including a depth gauge support (602) and a depth gauge (620) including a depth gauge plate (622) supported by the depth gauge support (602) for axial movement along the axis of rotation (R), the depth gauge plate (622) extending into the interior region (301) and the depth gauge support (602) attached to and extending from the frame body (202).
    Type: Application
    Filed: September 7, 2012
    Publication date: March 13, 2014
    Applicant: Exsurco Medical, Inc.
    Inventors: Bernard J. Esarey, Jason A. Sukey, Jeffrey A. Whited
  • Publication number: 20140074119
    Abstract: A hand-held, power operated debridement tool (2000) includes a rotary disk knife blade (2300) with a cutting edge (2360) on an outer peripheral edge (2362) of the knife blade, the cutting edge defining a cutting plane (CP) of the disk knife blade. The debridement tool further includes an annular skin guide (2700) including an outer wall (2716) defining a skin contact surface (2720) disposed above the cutting plane (CP) of the disk knife blade and positioned radially inwardly of the disk knife blade cutting edge to receive and direct an excised layer of skin tissue (EST) cut by the disk knife blade upwardly away from the blade cutting edge. The debridement tool additionally includes an axially adjustable depth gauge (2620) including a depth gauge plate (2622) disposed above the cutting plane of the disk knife blade and positioned radially outwardly of the cutting edge of the disk knife blade.
    Type: Application
    Filed: March 6, 2013
    Publication date: March 13, 2014
    Applicant: Exsurco Medical, Inc.
    Inventors: Bernard J. Esarey, Jeffrey A. Whited
  • Publication number: 20140066957
    Abstract: A dermatome having a main body, a blade assembly and a blade guard, where the blade assembly has a blade edge and the blade guard has a base and a fence extending from the base toward the blade assembly so as to face the blade edge. The blade guard may include at least one blade assembly locator to facilitate the alignment of the blade guard with the blade assembly. A blade guard assembled on the blade assembly may operate so as to prevent unintended contact between the blade edge and objects.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 6, 2014
    Applicant: Zimmer Surgical, Inc.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20140066956
    Abstract: Methods and devices to process harvested skin tissue and to immediately reintroduce the ground tissue into the patient to repair a tissue defect are disclosed. A hand-held portable tissue grinder comprising a housing and a grinding element are disclosed. The tissue grinder is used for grinding skin and subcutaneous tissue and includes a sterile polymer housing having a first opening adapted to receive the skin and subcutaneous tissue. The tissue grinder also includes a sterile grinding element disposed substantially within the housing.
    Type: Application
    Filed: October 21, 2013
    Publication date: March 6, 2014
    Inventor: Omeed Memar
  • Publication number: 20140046344
    Abstract: The invention generally relates to devices for generating and transferring micrografts and methods of use thereof. In certain embodiments, devices of the invention include a housing having an open configuration and a closed configuration, a micrograft generating station, and a micrograft transferring station.
    Type: Application
    Filed: September 5, 2013
    Publication date: February 13, 2014
    Applicant: MoMelan Technologies, Inc.
    Inventors: Sameer Sabir, Brian Newkirk, Andrew Ziegler, Denis Labombard
  • Publication number: 20140039427
    Abstract: The present invention provides skin grafting and devices that comprise a systematic approach to the process of skin grafting, i.e., harvesting, post-excision processing and application of donor skin and pre and post-graft treatment of the recipient site.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicant: KCI Licensing, Inc.
    Inventors: Charles Seegert, Royce Johnson, A. David Boccuti, Andrew Nicholas Gentile, Edward S. Griffey, Blane Sanders
  • Patent number: 8636749
    Abstract: A dermatome having a main body, a blade assembly and a blade guard, where the blade assembly has a blade edge and the blade guard has a base and a fence extending from the base toward the blade assembly so as to face the blade edge. The blade guard may include at least one blade assembly locator to facilitate the alignment of the blade guard with the blade assembly. A blade guard assembled on the blade assembly may operate so as to prevent unintended contact between the blade edge and objects.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: January 28, 2014
    Assignee: Zimmer Surgical, Inc.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Patent number: 8623031
    Abstract: A dermal tissue transplantation system combining a tissue particle harvester, a tissue particle collector, and a chambered dressing. The system provides a harvester capable of harvesting tissue from a donor site on the order of about 100 microns. The integrated tissue particle collector provides a means for collecting the harvested tissue for in situ cultivation in a chambered dressing at the wound site.
    Type: Grant
    Filed: February 15, 2010
    Date of Patent: January 7, 2014
    Assignee: KCI Licensing, Inc.
    Inventors: Elof Eriksson, Royce Johnson, Ajit Mishra, Michael Girouard, Makoto Ohira, Jonathan Kagan
  • Patent number: 8617181
    Abstract: The present invention generally relates to methods for preparing a skin graft. In certain embodiments, methods of the invention involve harvesting a plurality of skin grafts from a subject, applying the grafts to a first substrate, stretching the first substrate, and transferring the grafts from the first substrate to at least a second substrate for application to a patient recipient site.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: December 31, 2013
    Assignee: Momelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, M Josh Tolkoff, Andrew Ziegler, Denis LaBombard
  • Patent number: 8608755
    Abstract: A dermatome having a main body, a blade assembly and a bottom member, where the main body includes a bottom surface and at least one capture extending from the bottom surface. The bottom member may be inserted into the at least one capture and fastened to the main body, where the blade assembly may be mounted between the fastened bottom member and the bottom surface of the main body. The captures of the main body may limit the movement of the inserted bottom member in at least three general directions and the fastener may limit the movement of the bottom member in at least a fourth general direction.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: December 17, 2013
    Assignee: Zimmer Surgical, Inc.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20130304088
    Abstract: A dermatome assembly is operable to harvest a skin graft and includes an ultrasonic dermatome and a power supply. The ultrasonic dermatome includes a body and an ultrasonic blade assembly mounted in the body. The blade assembly includes a frequency generator and a cutting horn powered by the frequency generator. The cutting horn is spaced apart from the body so that the body is restricted from damping vibrational movement of the cutting horn. The dermatome assembly is operable to precisely control the thickness of the cut skin graft and also restrict the cutting horn from overheating.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 14, 2013
    Inventors: James Raymond Lucas, Mark Loyd Jones, James Earl Alrdrich, Peter Barrett Lucas, Norbert Russ, Shane E. Cowden
  • Publication number: 20130289582
    Abstract: A dermatome having a blade assembly, where the blade assembly includes a blade and a blade mount. The blade may include a blade edge, a reference edge and at least one hole or receiver positioned between the blade edge and the reference edge. The blade mount may include a base, a blade locator extending from the base and at least one reference fence abutting the reference edge of the blade. The blade locator may include a protrusion for inserting into the hole or receiver of the blade. The blade and blade mount of the blade assembly may self align and provide for a simple and permanent connection.
    Type: Application
    Filed: July 2, 2013
    Publication date: October 31, 2013
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Patent number: 8562626
    Abstract: The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: October 22, 2013
    Assignee: Momelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, Andrew Ziegler
  • Publication number: 20130274763
    Abstract: A system for treating a tissue site is provided, the system including a graft preparation device for treating a tissue site, the preparation device including an elongate inner member having a proximal end connected to a handle and a distal end including an abrasive end configured for abrading the tissue site, and an elongate outer member movably attached to the elongate inner member, the elongate outer member including a tapered end. The elongate outer member is movable between a first position for covering the abrasive end and a second position for exposing the abrasive end. Following treatment of the tissue site using the graft preparation device to remove soft tissue and cause bleeding, the tissue site is distracted and an implant body is inserted into the tissue site.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 17, 2013
    Applicant: Warsaw Orthopedic, Inc.
    Inventors: Susan J. Drapeau, Daniel A. Shimko
  • Patent number: 8535239
    Abstract: A dicing device dices tissue harvested from a patient. The dicing device comprises a grid cutting element and a tray to receive diced tissue. The dicing device may be integrated into an otherwise conventional biopsy device. The diced tissue specimens may be further processed, such as by being introduced into a self-expanding fistula plug creation and delivery system. The self-expanding fistula plug creation and delivery system comprises a sheet and a reinforcement tube. A scaffold material may be placed in the sheet, which may then be folded and reinforced, with the scaffold material being compressed in the sheet. The scaffold material may then be pushed into a catheter end. The catheter end may be inserted in a fistula. The scaffold material may then be flushed with a cell matrix that is based on the diced tissue to create a fistula plug, which may be left in the fistula.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: September 17, 2013
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Sean P. Conlon, Joanne Hull, Wells D. Haberstich
  • Patent number: 8512354
    Abstract: A dermatome having a blade assembly, where the blade assembly includes a blade and a blade mount. The blade may include a blade edge, a reference edge and at least one hole or receiver positioned between the blade edge and the reference edge. The blade mount may include a base, a blade locator extending from the base and at least one reference fence abutting the reference edge of the blade. The blade locator may include a protrusion for inserting into the hole or receiver of the blade. The blade and blade mount of the blade assembly may self align and provide for a simple and permanent connection.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: August 20, 2013
    Assignee: Zimmer Surgical, Inc.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20130204273
    Abstract: The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 8, 2013
    Applicant: MoMelan Technologies, Inc.
    Inventor: MoMelan Technologies, Inc.
  • Publication number: 20130110132
    Abstract: Described herein are conditioned medium and processed conditioned medium, each of which comprises secreted stem cell factors; compositions containing conditioned medium and/or processed conditioned medium and a delivery polymer. The conditioned medium, processed conditioned medium and compositions may be used to promote blood vessel growth and healing of injured tissues.
    Type: Application
    Filed: April 5, 2011
    Publication date: May 2, 2013
    Applicant: MedStar Health Research Institute, Inc.
    Inventors: Stephen E. Epstein, Mary Susan Burnett, Amir Najafi
  • Publication number: 20130090669
    Abstract: Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for harvesting the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Exemplary embodiments of the invention provide a genetically modified dermal micro-organ expressing at least one recombinant gene product. Some embodiments of the invention provide methods and apparatuses for implanting a genetically modified DMO.
    Type: Application
    Filed: November 28, 2012
    Publication date: April 11, 2013
    Applicant: MEDGENICS MEDICAL ISRAEL LTD.
    Inventor: MEDGENICS MEDICAL ISRAEL LTD.
  • Publication number: 20130018389
    Abstract: A dermatome having a blade assembly, where the blade assembly includes a blade and a blade mount. The blade may include a blade edge, a reference edge and at least one hole or receiver positioned between the blade edge and the reference edge. The blade mount may include a base, a blade locator extending from the base and at least one reference fence abutting the reference edge of the blade. The blade locator may include a protrusion for inserting into the hole or receiver of the blade. The blade and blade mount of the blade assembly may self align and provide for a simple and permanent connection.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 17, 2013
    Applicant: ZIMMER SURGICAL, INC.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20130018391
    Abstract: A dermatome having a main body, a blade assembly and a blade guard, where the blade assembly has a blade edge and the blade guard has a base and a fence extending from the base toward the blade assembly so as to face the blade edge. The blade guard may include at least one blade assembly locator to facilitate the alignment of the blade guard with the blade assembly. A blade guard assembled on the blade assembly may operate so as to prevent unintended contact between the blade edge and objects.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 17, 2013
    Applicant: ZIMMER SURGICAL, INC.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20130018390
    Abstract: A dermatome having a main body, a blade assembly and a bottom member, where the main body includes a bottom surface and at least one capture extending from the bottom surface. The bottom member may be inserted into the at least one capture and fastened to the main body, where the blade assembly may be mounted between the fastened bottom member and the bottom surface of the main body. The captures of the main body may limit the movement of the inserted bottom member in at least three general directions and the fastener may limit the movement of the bottom member in at least a fourth general direction.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 17, 2013
    Applicant: ZIMMER SURGICAL, INC.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20120323259
    Abstract: A kit of components for extracting and storing a skin tissue sample includes an extraction cartridge with a plurality of blades, an actuator cartridge, and a cap with an aqueous preservative. The actuator cartridge is removeably attached to the extraction cartridge and causes the plurality of blades of the extraction cartridge to extract a skin tissue sample from the person. After the skin tissue sample is extracted, the cap is attached to the extraction cartridge to store and suspend the skin tissue sample in an aqueous preservative preloaded in a container in the cap. A liquid-tight seal prevents bodily fluids from contaminating the actuator cartridge and this enables the actuator cartridge to be removed from the extraction cartridge and to be reused. The extraction cartridge and the attached cap, which store the skin tissue sample, are sent to medical laboratory so that the skin tissue sample can be analyzed.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 20, 2012
    Inventor: WILL RICHARDSON
  • Publication number: 20120316576
    Abstract: A dermatome having a handle and an attachment including a valve, where the valve may include a first bobbin at least partially defining a first flow path and a second flow path, a second bobbin at least partially defining a first flow path, an inlet port at least partially defined by the second bobbin and an outlet port at least partially defined by the first bobbin. The ports of the valve may open in response to an application of a mechanical act to the attachment and the ports may close in response to the absence or removal of the mechanical act.
    Type: Application
    Filed: June 8, 2011
    Publication date: December 13, 2012
    Applicant: ZIMMER SURGICAL, INC.
    Inventors: Mark Mahaffey, Bruce Straslicka
  • Publication number: 20120271320
    Abstract: Devices and methods for obtaining a plurality of skin tissue particles for use in skin grafting.
    Type: Application
    Filed: April 19, 2012
    Publication date: October 25, 2012
    Applicant: KCI Licensing, Inc.
    Inventors: Colin John Hall, Anissa Lloyd, Christopher Brian Locke, Paul Slack
  • Publication number: 20120201793
    Abstract: Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for producing the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, having dimensions selected so as to allow passive diffusion of adequate nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. Some embodiments of the invention provide methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure.
    Type: Application
    Filed: February 9, 2012
    Publication date: August 9, 2012
    Inventors: Stephen F. Bellomo, Itzhak Lippin, Guillermo Alberto Piva, Lior Rosenberg, Mordechay Bukhman, Baruch S. Stern, David Shalhevet, Menachem D. Shavitt, Andrew L. Pearlman, Noam Shani, Einat Almon
  • Publication number: 20120197267
    Abstract: The invention generally relates to devices for generating and transferring micrografts and methods of use thereof. In certain embodiments, devices of the invention include a housing having an open configuration and a closed configuration, a micrograft generating station, and a micrograft transferring station.
    Type: Application
    Filed: January 27, 2011
    Publication date: August 2, 2012
    Applicant: MOMELAN TECHNOLOGIES, INC.
    Inventors: Sameer Sabir, Brian Newkirk, Andrew Ziegler, Denis LoBombard
  • Publication number: 20120172894
    Abstract: The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister.
    Type: Application
    Filed: January 9, 2012
    Publication date: July 5, 2012
    Applicant: MoMelan Technologies, Inc.
    Inventors: Sameer Ahmed Sabir, Jeffrey Cerier, Andrew Ziegler