Bioabsorbable Patents (Class 606/154)
  • Patent number: 10420636
    Abstract: Described are stent graft devices and methods for their preparation and use. Expandable stent graft devices of the invention include inner and/or outer coverings uniquely applied and associated with surfaces of the stent. In certain described embodiments, bioremodelable materials such as ECM materials are vacuum pressed onto and/or around elements of a stent in the manufacture of a stent graft device.
    Type: Grant
    Filed: August 8, 2006
    Date of Patent: September 24, 2019
    Assignee: Cook Medical Technologies LLC
    Inventor: F. Joseph Obermiller
  • Patent number: 10130346
    Abstract: The invention relates to a device suitable for application of a curable fluid composition to encircle a bodily organ. The device comprises a monolithic piece of a flexible material having a length dimension with an inner surface and an outer surface, a first end and a second end, a width dimension, and two spaced-apart sides, wherein a portion of the length dimension proximal to the first end is configured to contact a portion of the length dimension proximal to the second end, the inner surface defining a hollow area between the two spaced-apart sides; and at least one inlet providing fluid communication between the outer surface and the inner surface, for introduction of the fluid into the hollow area.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: November 20, 2018
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Erez Ilan, Yotam Gurman, Moti Meron
  • Patent number: 10034669
    Abstract: Methods and devices are provided for anastomosing tissue in the body. In one exemplary embodiment, an anastomotic device is provided having an elongate tubular body that is disposable through a body lumen and that includes proximal and distal portions. The proximal and distal portions can each include a plurality of asymmetrical s-shaped slits and can each be adapted to expand upon rotation to form proximal and distal wings. The proximal and distal wings can extend toward one another to engage tissue therebetween and thereby form a passageway through the tissue.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: July 31, 2018
    Inventors: James E. Coleman, Christy Cummins
  • Patent number: 9974543
    Abstract: An anastomotic connector includes a tubular shell and a porous biocompatible liner configured to connect two or more natural and/or artificial lumens, such as blood vessels and/or grafts. The tubular shell may be bioabsorbable, ultimately dissolving in the body, while the biocompatible liner can remain in the body and connected to the lumens.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: May 22, 2018
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Jeffrey B. Duncan, James L. Goepfrich
  • Patent number: 9968716
    Abstract: The present invention provides a drug-eluting stent graft for preventing stent graft-related complications as well as treating aneurysm. Specifically, the present invention relates to a drug-eluting stent graft comprising a drug, a drug-retaining agent and a stent graft, and a method for therapy of aneurysm including the use of the drug-eluting stent graft.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: May 15, 2018
    Assignees: ONO PHARMACEUTICAL CO., LTD., OSAKA UNIVERSITY
    Inventors: Yoshiki Sawa, Toru Kuratani, Koichi Toda, Takayoshi Ueno, Shigeru Miyagawa, Satsuki Fukushima, Atsuhiro Saito, Yoshiki Watanabe, Yoshiki Sakai
  • Patent number: 9955969
    Abstract: A system and method for joining an end of a tubular prosthesis to the wall of a vessel wherein an anvil is inserted into the vessel through an opening in the vessel wall produced by a cutting surface on the anvil. The anvil is operated via an anvil handle which may extend through the tubular prosthesis. The tubular prosthesis is guided to the opening in the vessel wall whereupon jaws clamp the prosthesis around the anvil. Staples mounted on the jaws engage the anvil and are bent to thereby staple the end of the tubular prosthesis to the vessel wall. A cutting edge may be mounted to the anvil and utilized to create an enlarged hole to permit blood flow into the tubular prosthesis and to permit removal of the anvil from the vessel.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: May 1, 2018
    Assignee: TEXAS HEART INSTITUTE
    Inventor: William E. Cohn
  • Patent number: 9827135
    Abstract: According to some embodiments of the invention, an anchoring system includes a sleeve having an inner surface defining a first lumen, a first annular sealing mechanism disposed at a proximal end of the sleeve, and a second annular sealing mechanism disposed at a distal end of the sleeve. The anchoring system further includes a pressure tube in fluid connection with an outer surface of the sleeve, a sheath in mechanical connection with the sleeve, the sheath forming a second lumen, the second lumen being in fluid connection with the first lumen, and open-cell foam disposed on the outer surface of the sleeve. Application of negative pressure to the pressure tube causes a seal to form between the first and second annular sealing mechanisms and an inner surface of a tissue cavity. Application of negative pressure to the pressure tube also creates a frictional force that resists displacement of the sleeve.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: November 28, 2017
    Assignee: SAVAGE MEDICAL, INC.
    Inventors: Kenton D. Fong, Jan Lee, Jeffrey W. Etter
  • Patent number: 9820743
    Abstract: Techniques for sutureless vascular anastomosis are described, including an incision seal including a base configured to partially house an outer surface of a main vessel, the base being formed using a material that is configured to be penetrated by a barb disposed on a connector the main vessel being secured to the base when the base is at least partially pierced by the barb, an upper lumen configured to guide a graft vessel, and a housing opening configured to receive the graft vessel.
    Type: Grant
    Filed: December 31, 2010
    Date of Patent: November 21, 2017
    Assignee: Asfora IP, LLC
    Inventors: Wilson Theophilo Asfora, Thomas Albert Roberts, Duane Lee Middlebusher, Richard Dean Phipps, Michael Edward Villalta, Lee James Carmack
  • Patent number: 9782277
    Abstract: The invention provides a system (1) and method for manufacturing a stent. A spraying device (14) sprays a polymeric suspension (16) onto a mandrel (4). During spraying of the polymeric suspension (16) onto the mandrel (4), the mandrel (4) is manipulated by a micromanipulator (8) to produce a continuous coating on the mandrel (4) having a nonuniform thickness. The polymeric coating is allowed to cure on the mandrel (4) to form the stent, which is then removed from the mandrel (4). The method can comprise embedding a filament (2) in the polymeric coating and incorporating one or more drugs in the stent.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: October 10, 2017
    Assignee: ALLIUM MEDICAL SOLUTIONS LTD.
    Inventors: Daniel Yachia, Ziv Kalfon
  • Patent number: 9744286
    Abstract: A connection system for creating a vascular cannula for connection to a blood vessel includes a flexible hose element in the form of a graft, a conduit element and, disposed therebetween, a connecting element establishing fluid-tight connections, wherein a retaining element is equipped with a radially outwardly elastically beadable snap ring, which, in the connected state, can be snapped in behind a detent surface of one of the parts of the connection system.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: August 29, 2017
    Assignee: Berlin Heart GmbH
    Inventors: Manfred Göllner, Uwe Samlenski
  • Patent number: 9339369
    Abstract: The present invention provides for an implantable medical device comprising a hybrid composite material including a first biological component such as an acellular tissue matrix and a second non-biological component for strengthening the device after implantation.
    Type: Grant
    Filed: May 9, 2007
    Date of Patent: May 17, 2016
    Assignee: LifeCell Corporation
    Inventors: David J. McQuillan, John R. Harper, Christopher T. Wagner, E. Skott Greenhalgh
  • Patent number: 9326860
    Abstract: A biologic artificial bone includes an artificial fiber material formed from a synthetic polymer with mechanical properties similar to type I collagen. A biocompatible liquid substance is impregnated in the fiber material that hardens and stiffens the fiber material. A bone substitute is impregnated in the hardened and stiffened fiber material forming an artificial bone composite. Vascular channels are formed in the artificial bone composite to facilitate in-growth of vessels and bone forming cells. The construction and methods achieve an artificial composite structure that is similar to natural bone with comparable properties.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: May 3, 2016
    Assignee: Amendia, Inc.
    Inventor: Said G. Osman
  • Patent number: 9151356
    Abstract: A splice is described for jointing thermoplastic strips that include steel cords. In the splice a splice polymer is used that is a mixture of a co-polymer and a base polymer, wherein the co-polymer is a grafted co-polymer, a block co-polymer or a random co-polymer functionalized for enabling adhesion to the steel cords. Particular about the inventive splice is that the amount of co-polymer in the base polymer is such that in a test-till-break of a splice, part of the steel cords fracture in the test while the remaining cords are pulled out of the polymer without breaking. Surprisingly, a splice with such a failure behavior results in a better overall splice strength than a splice wherein a too large amount of co-polymer is added. When too much co-polymer is added all steel cords break in the test which strangely enough leads to a lower overall strength of the splice.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: October 6, 2015
    Assignee: NV BEKAERT SA
    Inventor: Anneleen De Smet
  • Patent number: 9101453
    Abstract: A urological repair device includes a stent having a diameter that fits within a portion of a urological structure. The stent also has a length to bridge a distance between a first end of the urological structure and a second end of the urological structure. The stent includes at least one tapered end. The tapered end enables placement of the stent within the urological structure. A method of repairing a urological structure includes placing a first end of a substantially tubular urological structure over a first end of a tubular stent, and placing a second end of a substantially tubular urological structure over a second end of a stent, and attaching the first end of the substantially tubular urological structure, the second end of a substantially tubular urological structure, and the tubular stent to form a fluid passageway.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: August 11, 2015
    Inventor: Greg Harold Albers
  • Patent number: 9060772
    Abstract: A surgical device and method used to assist in the surgical repair and rehabilitation of damaged and/or severed tendons. In one embodiment of the present invention, the device includes a hollow member, preferably shaped as a partial funnel and/or cone, having an inner and outer surface, a flared mouth, a shaft, and an apical end. In another embodiment, the device includes a hollow member, preferably shaped as funnel or barrel cut in half along its longitudinal axis, having an inner and outer surface, two flared mouths, and a shaft.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: June 23, 2015
    Assignee: TOBY ORTHOPAEDICS, INC.
    Inventor: Eduardo Gonzalez-Hernandez
  • Patent number: 9050419
    Abstract: An endovascular anastomotic connector and method of using the same. The endovascular anastomotic connector includes a vascular conduit and a supply conduit. The vascular conduit has proximal and distal ends that reside within a vascular structure. The supply conduit extends at an angle from the vascular conduit. The proximal end of the supply conduit is configured to be attached to an auxiliary device.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: June 9, 2015
    Assignee: CIRCULITE, INC.
    Inventor: Robert C. Farnan
  • Patent number: 9005184
    Abstract: For fixedly implanting a device for material or signal delivery or acquisition or a part of such a device in a human or animal body, an opening is provided in hard tissue of the body, the opening reaching through a hard tissue layer, e.g. through a cortical bone layer into cancellous bone underneath. The device includes a plug portion (P) and/or a cover portion (C) which includes a ring of a material having thermoplastic properties extending around the plug portion (P) or on a tissue facing surface of the cover portion (C). The opening provided in the hard tissue has a cross section at least in the area of its mouth that is adapted to the plug or cover portion such that the plug portion (P) can be introduced through the mouth of the opening or the cover portion (C) can be positioned over the mouth of the opening such that the ring extends around the opening, along its wall and/or on the hard tissue surface around its mouth.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: April 14, 2015
    Assignee: Woodwelding AG
    Inventors: Jörg Mayer, Barbara Froesch, Mario Lehmann, Jens Langhoff, Thomas Knecht, Stephanie Mehl, Andrea Mueller
  • Publication number: 20150039001
    Abstract: The present invention relates to devices and methods for creating and securing a tissue fold during an endoluminal medical procedure. The devices and methods may be used for folding and securing, for example, a fundus wall onto an esophagus wall. An aspect of the invention includes a two-piece tissue clip configured to be installed through an endoluminal device to secure a tissue fold. The clip includes a female member and a male member configured to engage one another to secure the tissue fold. Another aspect of the invention includes a clipping device comprising a tissue clip magazine. The magazine is configured to hold a plurality of tissue clips and install the plurality of tissue clips in a single actuation of the magazine. A method for using the clipping device together with the tissue clips of the present invention to create and secure a fold of tissue during an endoluminal procedure also is disclosed.
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventor: Kurt E. GEITZ
  • Publication number: 20150039000
    Abstract: Methods and systems are provided for fixating connective tissue to bone. Some aspects include a carrier member having a length, width, and thickness, wherein the length and width are each at least two times greater than the thickness; attachment members extending from the carrier member and that engage connective tissue of an animal; and a bone engaging member extending from the carrier member and configured to attach to a bone of the animal. In some aspects, when the attachment members are engaged with the connective tissue and the bone engaging member is attached to the bone, the connective tissue and the bone are limited in being pulled apart from one another during physiological use of the connective tissue.
    Type: Application
    Filed: August 16, 2014
    Publication date: February 5, 2015
    Inventor: Erik N. Kubiak
  • Publication number: 20150018855
    Abstract: A leakage detecting implant can detect leakage of body fluid from an incision, resection, or other internal surgical site in a subject. The leakage detecting implant can include: one or more biodegradable colorant members having a tissue-contacting inner surface and an opposite outer surface; a resilient member having an inner surface coupled to the outer surface of the one or more colorant members; and a cover member having a body with an internal chamber and an opening on a tissue-contacting side, the internal chamber containing the resilient member and at least a portion of the one or more biodegradable colorant members with the tissue-contacting inner surface exposed through the opening, the cover member having an inner surface of the internal chamber coupled to an outer surface of the resilient member, the tissue-contacting side having one or more affixation surfaces adapted to be affixed to tissue of a subject.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 15, 2015
    Inventors: Prashant Borkar, Mangesh Patankar, Rahul Nair, Cinish Puthiyedathu Varghese
  • Patent number: 8894699
    Abstract: Methods and apparatus for anastomosis of a lumen according to various aspects of the present invention operate in conjunction with an impermeable stent. The impermeable stent may comprise a scaffold and, if needed, a sealant, such as a membrane and/or adhesive. In one embodiment, the scaffold, membrane and/or adhesive comprise biocompatible materials suitable for bio-absorption and/or degradation.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: November 25, 2014
    Assignee: Dr. Kelley Cancer Foundation
    Inventor: Jill Kelley
  • Publication number: 20140163589
    Abstract: The instant invention provides compositions and methods for promoting the repair and/or growth of biological tissue, e.g., tubular biological tissue such as nerves. Specifically, the instant invention provides tissue connection devices and tissue repair devices and methods for using these devices.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 12, 2014
    Applicant: The Johns Hopkins University
    Inventors: Ahmet Hoke, Hai-Quan Mao
  • Patent number: 8690902
    Abstract: Methods and devices are provided for enlarging an anastomosis fistula. In general, a surgical clip is applied to tissue surrounding a strictured anastomosis. The clip will exert a pressure on the engaged tissue that causes ischemic necrosis, and as a result the necrotic tissue and the clip will slough off, leaving an anastomosis with a larger diameter fistula.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: April 8, 2014
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventor: Christopher P. Swain
  • Patent number: 8636191
    Abstract: A surgical fastener for use with an anastomosis of two tissues includes a base leg and an upright leg. The base leg is selectively deformable and includes a traumatic tip for piecing tissue. The surgical fastener also includes at least one capillary disposed on the base leg which has a reservoir defined therein for retaining a liquid, e.g., bioadhesive, bonding agent, medicament, etc. Each of the capillaries is ruptureable upon deformation of the surgical fastener to dispense the liquid to the anastomosis site.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: January 28, 2014
    Assignee: Covidien LP
    Inventor: Edward C. Meagher
  • Patent number: 8617049
    Abstract: An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A symmetrical drive system including a drive element associated with and engaging the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct is further provided. In accordance with an alternate embodiment an apparatus for regulating the functioning of a patient's organ or duct including an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: December 31, 2013
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Daniel F. Dlugos, Jr., Toralf Bork, Christine H. Chen, Rocco Crivelli, Donna L. Korvick, David T. Krumanaker, Timothy P. Lessek, Amy L. Marcotte, Jeffrey D. Messerly, Daniel J. Mumaw, Anil K. Nalagatla, David N. Plescia, Frederick E. Shelton, IV, Jeffrey S. Swayze, Patrick J. Swindon, Mark Tsonton, Scott A. Woodruff
  • Publication number: 20130306707
    Abstract: An apparatus for forming an anastomosis between adjacent intestinal sections of tissue is provided. The apparatus includes a circular surgical stapler having an anvil assembly with an anvil shaft and an anvil, the circular surgical stapler further having a tubular body portion with an annular knife and a body portion shaft selectively attachable to the anvil shaft; and a seal structure for deposition between the intestinal sections of tissue including a hub configured to engage attachment structure on at least one of the anvil shaft and the body portion shaft. The attachment structure is positioned so that the seal structure is located between the intestinal sections of tissue when the circular surgical stapler is disposed within the intestinal sections of tissue.
    Type: Application
    Filed: July 23, 2013
    Publication date: November 21, 2013
    Applicant: Covidien LP
    Inventors: Frank J. Viola, Christopher J. Criscuolo, David Fowler, Michael J. Bettuchi, Danyel Tarinelli, Robert Capella, Kevin Sniffin, Ahmad R. Hadba
  • Publication number: 20130225900
    Abstract: A closure device having evertable arms for capturing and everting tissue and method for its use with an invasive scope, such as an endoscope, for full-thickness closure of perforations and leaks in the walls of an intraluminal bodily space.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 29, 2013
    Inventors: Anthony N. Kalloo, Mouen A. Khashab
  • Publication number: 20130178879
    Abstract: Methods and devices for modifying the location at which bodily fluids interact with nutrients in a gastrointestinal tract. The methods and devices utilize a conduit configured to divert bodily fluids from an entrance within a gastrointestinal tract to a location downstream from the entrance.
    Type: Application
    Filed: February 15, 2013
    Publication date: July 11, 2013
    Inventor: Michael D. LAUFER
  • Patent number: 8480694
    Abstract: The present disclosure relates a device for joining a first body vessel to a second body vessel, including an inner member having a distal end portion and defining a longitudinal axis, an outer member defining a lumen dimensioned to receive the inner member therein, and a radially expandable anchor disposed at the distal end of the inner member, the expandable anchor having an initial condition wherein the expandable anchor is disposed between the outer member and the inner member and an expanded condition wherein the expandable anchor is radially larger than the expandable anchor in the initial condition.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: July 9, 2013
    Assignee: Covidien LP
    Inventors: Russell Heinrich, Scott E. Manzo
  • Patent number: 8449563
    Abstract: Fragmentable compression device for the anastomosis of hollow organs consisting of a pot-shaped body composed of two elements (1, 2), inserted one into the other and consisting of a plurality of composable sectors (5, 6), a third ring-shaped or hollow cylinder-shaped element (3) intended to be inserted into said pot-shaped body to clamp the edges of the organs to be anastomized, and a fourth element (4) also ring-shaped or hollow cylinder-shaped which is pressure-inserted into element (3) to compress said edges. Also elements (3, 4) consist of a plurality of composable sectors (7, 8). The axial dimension of the device is notably short so that, when it is applied in the vicinity of the anal canal of the patient, tenesmus is considerably reduced.
    Type: Grant
    Filed: November 21, 2005
    Date of Patent: May 28, 2013
    Assignee: AB Medica S.p.A.
    Inventors: Carlo Rebuffat, Riccardo Rosati, Dante David
  • Publication number: 20130116713
    Abstract: The present invention relates to devices and methods for creating and securing a tissue fold during an endoluminal medical procedure. The devices and methods may be used for folding and securing, for example, a fundus wall onto an esophagus wall. An aspect of the invention includes a two-piece tissue clip configured to be installed through an endoluminal device to secure a tissue fold. The clip includes a female member and a male member configured to engage one another to secure the tissue fold. Another aspect of the invention includes a clipping device comprising a tissue clip magazine. The magazine is configured to hold a plurality of tissue clips and install the plurality of tissue clips in a single actuation of the magazine. A method for using the clipping device together with the tissue clips of the present invention to create and secure a fold of tissue during an endoluminal procedure also is disclosed.
    Type: Application
    Filed: December 20, 2012
    Publication date: May 9, 2013
    Inventor: Kurt E. Geitz
  • Patent number: 8349019
    Abstract: Apparatus and method for performing surgical anastomotic procedures are disclosed herein. The apparatus for performing the surgical anastomotic procedure includes a tubular sleeve defining an axial lumen therethrough, a positioning tube defining an axial lumen therethrough, an expansion assembly having a tubular body and an expandable tip operatively coupled to a distal end thereof, and an anchoring assembly. The positioning tube is preferably configured and adapted to be slidably received within the axial lumen of the tubular sleeve.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: January 8, 2013
    Assignee: Covidien LP
    Inventor: Scott Manzo
  • Patent number: 8343087
    Abstract: A prosthetic device for creating a vascular bypass from an arterial vessel has at least one prosthetic tube joined to an orifice of a flexible collar. The prosthetic tube extends from an outer face of the collar. The collar has an inner face surface for attachment to the arterial vessel. The collar has a connection zone has an annular cavity extending around and away from the orifice. The annular cavity is suitable for receiving an injected glue or bioabsorable haemostatic product so as to attach to the arterial vessel.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: January 1, 2013
    Assignee: Vascular Office (Sarl)
    Inventor: Maxime Formichi
  • Patent number: 8292154
    Abstract: A surgical apparatus for applying tissue fasteners is provided. The surgical apparatus includes a handle assembly, an elongated body that extends from the handle assembly, and a tool assembly mounted on the end of the elongate body. The tool assembly includes a cartridge assembly for receiving the tissue fasteners and a housing assembly for receiving a looped member. The tool assembly is configured to advance the tissue fasteners into the looped member to secure tissue between the fasteners and the looped member.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: October 23, 2012
    Assignee: Tyco Healthcare Group LP
    Inventor: Stanislaw Marczyk
  • Patent number: 8231646
    Abstract: Devices and methods are disclosed for the control of blood perfusion pressure within a blood vessel that undergoes arterialization. A cannula is introduced that contains a stenosis that either resorbs or is removed in time, allowing a gradual increase in blood pressure between two blood passages connected at either ends of the cannula. Particular emphasis has been made with the use of the cannula for the vessels in the heart.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: July 31, 2012
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 8216259
    Abstract: Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: July 10, 2012
    Assignee: The Board of Trustees of the Leland Stanford Jr. University
    Inventors: Geoffrey C. Gurtner, Gerald G. Fuller, Michael T. Longaker, Jayakumar Rajadas
  • Patent number: 8197499
    Abstract: Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 12, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Geoffrey C. Gurtner, Gerald G. Fuller, Michael T. Longaker, Jayakumar Rajadas, Gordon Saul, C. Travis Rappleye, Evgenia Mandrusov
  • Patent number: 8105622
    Abstract: Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: January 31, 2012
    Assignee: Incept LLC
    Inventor: Amarpreet S. Sawhney
  • Patent number: 8092482
    Abstract: Gastric space occupying devices are provided that include a stent configured for deployment in the gastrointestinal tract of a patient, and in particular, for deployment in the esophagus or the stomach. Secured to the stent is an expandable member that is adapted to reside within the patient's stomach. When expanded, the expandable member occupies a predefined volume within the patient's stomach and is further tethered to the deployed stent, thereby retaining or anchoring the expandable member within the stomach. Methods and systems for the deploying the space occupying devices are also provided.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: January 10, 2012
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: James Gannoe, Federico Gutierrez
  • Patent number: 8083804
    Abstract: Apparatus method for performing surgical anastomotic procedures are disclosed herein. The apparatus for performing the surgical anastomotic procedure includes a tubular sleeve defining an axial lumen therethrough, a positioning tube defining an axial lumen therethrough, an expansion assembly having a tubular body and an expandable tip operatively coupled to a distal end thereof, and an anchoring assembly. The positioning tube is preferably configured and adapted to be slidably received within the axial lumen of the tubular sleeve.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: December 27, 2011
    Assignee: Tyco Healthcare Group LP
    Inventor: Scott Manzo
  • Patent number: 8012164
    Abstract: An auger is axially fixed to and positioned within a cutter. The auger and cutter advance at the same time relative to a contact structure placed against a vessel, penetrating the wall of the vessel and cutting a tissue plug. When the auger and the cutter are retracted from the vessel wall, the tissue plug is retained by the auger and cutter and removed from the vessel wall. The auger and the cutter thus create an opening in the vessel wall, without the need for a prior incision in that wall.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: September 6, 2011
    Assignee: Cardica, Inc.
    Inventors: Brendan M. Donohoe, Theodore M. Bender, Brian R. DuBois, Scott O. Chamness, Stephen A. Yencho, Jaime S. Vargas, Nathan H. White, Gregory B. Arcenio, Heather L. Klaubert, Russell C. Mead, Jr.
  • Patent number: 7914552
    Abstract: A method and instruments used to performing an end-to-end anastomosis between two portions of intestinal tissue is disclosed. The method involves drawing a first portion of intestinal tissue over a portion of a bioabsorbable stent. The end of the first portion of intestinal tissue is everted on the stent to create a collar of exposed inner intestinal tissue. A second portion of intestinal tissue is drawn over the stent and over the exposed intestinal tissue. A bandage containing one adhesive compound selected from the group of an adhesive and an adhesive initiator is wrapped about the juncture. The other adhesive compound is applied to saturate the bandage and the combination of an adhesive and an adhesive initiator sets the adhesive to adhere the first portion and the second portion of adhesive to the bandage.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: March 29, 2011
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventor: Frederick E. Shelton, IV
  • Patent number: 7909886
    Abstract: This invention is directed to prosthesis, which, when implanted into a mammalian patient, serves as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patient's living cells. The prosthesis is treated so that it is rendered non-antigenic so as not to elicit a significant humoral immune response. The prosthesis of this invention, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: March 22, 2011
    Assignee: Organogenesis, Inc.
    Inventors: Robert M. Carr, Jr., Kimberlie D. Condon, Paul L. Termin, Janet Hardin Young
  • Patent number: 7837645
    Abstract: An endoscopic device separates ingested food from gastric fluids or gastric fluids and digestive enzymes, to treat obesity. In a particular embodiment a gastric bypass stent comprises a tubular member and two or more stent members defining a lumen. The tubular member has a substantially liquid impervious coating or covering and one or more lateral openings to permit one-way liquid flow.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: November 23, 2010
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Marc Bessler, John D. Allendorf
  • Patent number: 7780687
    Abstract: The present disclosure relates a device for joining a first body vessel to a second body vessel, including an inner member having a distal end portion and defining a longitudinal axis, an outer member defining a lumen dimensioned to receive the inner member therein, and a radially expandable anchor disposed at the distal end of the inner member, the expandable anchor having an initial condition wherein the expandable anchor is disposed between the outer member and the inner member and an expanded condition wherein the expandable anchor is radially larger than the expandable anchor in the initial condition.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: August 24, 2010
    Assignee: Tyco Healthcare Group LP
    Inventors: Russell Heinrich, Scott E. Manzo
  • Patent number: 7758825
    Abstract: A handle assembly facilitates the removal of a sterile inner tray containing sterile medical instruments from a medical kit during an OR procedure. The handle assembly may have a handle coupled with an elongated member having a male end and a female end. The inner tray may be wrapped in medical packaging. Subsequently, the elongated member may be wrapped around the inner tray and the male and female ends interconnected. The inner tray may be positioned inside of an outer tray. A bacterial barrier may be formed over a portion of the outer tray to enclose the inner tray. The inner tray, including the medical instruments, may then be sterilized by a sterilization process. During an OR procedure, the handle assemble allows a sterile nurse to remove the sterile inner tray from the non-sterile outer tray without making contact with the non-sterile outer tray and/or contaminating the sterile medical instruments.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: July 20, 2010
    Assignee: Cook Incorporated
    Inventor: Chris R. Kabrick
  • Publication number: 20100174300
    Abstract: A method for performing end-to-end vessel anastomosis includes providing a vessel support including a vessel receiving portion and a handle portion extending therefrom. The vessel receiving portion is an annulus. The vessel receiving portion is positioned around the end of a first vessel and the end of the first vessel is everted about the outer diameter of the vessel receiving portion such that the inner surface of the vessel is directed outwardly. The end of the second vessel is positioned over the everted end of the first vessel such that the inner surface of the second vessel is disposed against the inner surface of the first vessel. The ends of the vessel are secured either with a suture or a surgical adhesive. The handle portion of the vessel support may be removed.
    Type: Application
    Filed: June 20, 2008
    Publication date: July 8, 2010
    Inventor: Phillip Nicolas Blondeel
  • Patent number: 7736393
    Abstract: Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/?-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2<L(LA)<[LA%/(LA%+GA%+CL%)]×X×0.058??(1) 1<L(GA)<[GA%/(LA%+GA%+CL%)]×X×0.58??(2) 1<L(CL)<[CL%/(LA%+GA%+CL%)]×X×0.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: June 15, 2010
    Assignee: Kawasumi Laboratories, Inc.
    Inventors: Noriaki Shirahama, Tomokazu Mukai, Takao Okada, Yukari Imamura, Yoshimichi Fujiyama
  • Patent number: 7648713
    Abstract: Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: January 19, 2010
    Assignee: Incept LLC
    Inventor: Amarpreet S. Sawhney
  • Patent number: RE47154
    Abstract: Vascular access systems for performing hemodialysis are disclosed. The vascular access system contemplates a catheter section adapted for insertion into a vein and a graft section adapted for attachment to an artery. The catheter section may have metal or polymer wall reinforcements that allow the use of thin-walled, small outer diameter conduits for the vascular access system. One or more of the adhered, embedded or bonded conduit reinforcement structures may be removable without significant damage to the conduit sections to facilitate attachment of the sections, or to a connector between the sections. Various self-sealing materials are provided for use in the vascular access system, as well as temporary access sites and flow control/sensor systems.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: December 11, 2018
    Assignee: Merit Medical Systems, Inc.
    Inventors: Christopher H. Porter, Laurie E. Lynch, Judson A. Herrig, Robert J. Ziebol