Internal Application Patents (Class 606/21)
  • Patent number: 10786296
    Abstract: A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: September 29, 2020
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Scott W. Davie
  • Patent number: 10758292
    Abstract: A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: September 1, 2020
    Assignee: AEGEA MEDICAL INC.
    Inventors: Hugh R. Sharkey, Ramiro Reyes, Kurt D. Sparks
  • Patent number: 10695041
    Abstract: A positioning device is configured to selectively position or otherwise manipulate one or more organs within the body of a subject. The positioning device includes a shaped expandable element that is configured to be selectively transitioned between an unexpanded, or collapsed, state and an expanded state. While in the expanded state, the expandable element repositions or otherwise manipulates an organ. Systems that include positioning devices are also disclosed, as are methods for positioning or otherwise manipulating organs.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 30, 2020
    Assignee: Manual Surgical Sciences LLC
    Inventor: Shawn P. Fojtik
  • Patent number: 10695126
    Abstract: Ablation catheters and systems include coaxial catheter shafts with an inner lumen for delivering an ablative agent and an outer lumen for circulation of a cooling element about the catheter. Induction heating is used to heat a chamber and vaporize a fluid within by wrapping a coil about a ferromagnetic chamber and providing an alternating current to the coil. A magnetic field is created in the area surrounding the chamber which induces electric current flow in the chamber, heating the chamber and vaporizing the fluid inside. Positioning elements help maintain the device in the proper position with respect to the target tissue and also prevent the passage of ablative agent to normal tissues.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: June 30, 2020
    Inventor: Virender K. Sharma
  • Patent number: 10682170
    Abstract: An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 16, 2020
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Luc Pageard
  • Patent number: 10667854
    Abstract: An endovascular near critical fluid based cryoablation catheter for creating an elongated lengthwise-continuous lesion in tissue can comprise an elongated shaft, a flexible distal tissue treatment section, and a distal tip. A plurality of flexible tubes can extend through the distal treatment section to transport a near critical fluid to and from the distal tip. The distal treatment section can also include a flexible fluid-sealed cover or barrier layer surrounding the delivery tubes. The cover and tubes can collectively define a space which is filled with a fluidic thermally conductive media. The thermally conductive media, fluid delivery tubes, and the cover can be arranged such that a flow of the near critical fluid through the tube bundle transfers heat between a target tissue and the distal treatment section of the catheter thereby creating the elongated lengthwise-continuous lesion in the tissue.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: June 2, 2020
    Assignee: Adagio Medical, Inc.
    Inventors: Alexei V. Babkin, Steven W. Kovalcheck, Xiaoyu Yu
  • Patent number: 10636324
    Abstract: Training device for training tracheal suctioning. The training device includes a tracheal core adapted to be arranged within a tracheal, nasal or oral cavity of a medical training simulator, and coupled to the airways of the simulator and an insert adapted to be inserted into the core, the insert forming a reservoir for simulated mucus.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: April 28, 2020
    Assignee: Laerdal Medical AS
    Inventors: Greg Necessary, Ben Tedeschi, Paul Griffith, David Thane
  • Patent number: 10610280
    Abstract: The embodied invention is a method of removing intraperitoneal fat by using a freezing cryoprobe and inserting it into the abdominal cavity. The freezing cryoprobe is covered by a vacuum sleeve which provides for a method for abdominal fat removal once the cells are damaged. A multi-step surgical procedure is used to freeze, irrigate, and remove the destroyed fat tissue. Also, an ultrasonic transmitter is inserted into an outer cryoprobe sheath to assess organ position with the advantage of an internal transmitter which greatly aids in organ identification.
    Type: Grant
    Filed: February 2, 2019
    Date of Patent: April 7, 2020
    Inventor: Ayad K. M. Agha
  • Patent number: 10596030
    Abstract: A method in which a location is determined on the skin that is proximate to a sensory nerve that is associated with a painful condition. At least one needle of a cryogenic device is inserted into the location on the skin such that the needle is proximate to the sensory nerve. The device is activated such that the at least one needle creates a cooling zone about the sensory nerve, thereby eliminating or reducing severity of the painful condition.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: March 24, 2020
    Assignee: Pacira CryoTech, Inc.
    Inventors: Jwala Karnik, Jason Reynolds, John Allison, Clint Carnell
  • Patent number: 10588682
    Abstract: Embodiments related to cryogenically ablating a portion of the inner surface of a vessel by constraining a cryoballoon using various apparatuses and methods are disclosed. For example, a catheter can include a cryoballoon for ablation of the vessel wall and a constraining element disposed substantially in parallel with the cryoballoon to deflect or offset a portion of the cryoballoon away from non-target tissue of the vessel wall and prevent ablation of the non-target tissue. Partial circumferential, non-continuous, or helical ablation can be effective for treating a variety of renal, cardio-renal, and other diseases including but not limited to hypertension, heart failure, renal disease, renal failure, contrast nephropathy, arrhythmia, and myocardial infarction. The constraining element may be, for example, a second inflatable balloon or one or more self-expanding prongs.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: March 17, 2020
    Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
    Inventors: Brian Kelly, John Kelly, Gary P. Kelly, Barry Mullins
  • Patent number: 10512460
    Abstract: A system (10) including an helicoidal member (16); an elongated guide (26) positionable at least partially through the helicoidal member (16) along the longitudinal axis of helicoidal member (16), the guide (26) defining a longitudinally extending peripheral surface cooled portion (32); a cooling subsystem (33) for cooling the peripheral surface cooled portion (32); and a driver (34) for mounting the helicoidal member (16) thereto and rotating the helicoidal member (16) along the helicoidal member longitudinal axis while allowing the helicoidal member (16) to advance along the guide (26) in a distally oriented direction.
    Type: Grant
    Filed: December 19, 2015
    Date of Patent: December 24, 2019
    Inventors: Toufic Azar, Renzo Cecere
  • Patent number: 10478633
    Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 19, 2019
    Assignee: BTL Medical Technologies S.R.O.
    Inventors: Tomás Schwarz, Ondra Prouza
  • Patent number: 10471269
    Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 12, 2019
    Assignee: BTL Medical Technologies S.R.O.
    Inventors: Tomás Schwarz, Ondra Prouza
  • Patent number: 10456185
    Abstract: A method for reshaping a nasal airway in a patient involves advancing an inflatable balloon of a reshaping device in an uninflated configuration into a nostril of the patient and between a nasal septum and a lateral wall of the nasal airway. The method then involves inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to contact nasal mucosa covering the nasal septum and the lateral wall, delivering energy from an energy delivery member attached to or inside of the inflatable balloon, and removing the reshaping device from the nasal airway.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: October 29, 2019
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10441338
    Abstract: A system and method for creating radial-linear lesions in tissue. The system includes a cryoablation device having a first balloon, a second balloon disposed about the first balloon, and one or more splines disposed between the first balloon and second balloon, each spline defining a plurality of ports. The splines may be in communication with a coolant supply, and the first balloon may be in communication with a coolant supply or non-coolant inflation fluid supply. When the first balloon is in the uninflated configuration, the splines may have a substantially linear configuration. Each of the splines may be radially oriented about an elongate shaft and transitionable between the substantially linear configuration and an arcuate configuration when the first balloon is in the inflated configuration. Coolant expelled from the splines between the first and second balloons creates an ablation pattern on the outer surface of the second balloon.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: October 15, 2019
    Assignee: Medtronic CryoCath LP
    Inventors: George D. Mallin, Claudia Lueckge
  • Patent number: 10441339
    Abstract: Flexible apparatus for ablating unhealthy spinal tissue. A housing includes a distal end and a proximal end. Multiple thermocouples mounted on the housing measure spinal tissue temperatures at locations between the proximal end and the distal end. A sensor measures spinal tissue impedance. The measured spinal tissue impedance corresponds to various physical state data of the spinal tissue. The spinal tissue impedance and the spinal tissue temperatures are displayed to the surgeon, enabling the surgeon to determine with certainty the location of the unhealthy spinal tissue, and to exercise control over the ablation apparatus. Nerve stimulation by IMP/STM switch system to detect nerve responses before and after treatment.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: October 15, 2019
    Assignee: Medtronic Holding Company Sárl
    Inventors: Stephen W. Lee, Michael A. Smith, Dawud F. Dueiri
  • Patent number: 10441459
    Abstract: Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: October 15, 2019
    Assignees: Ethicon Endo-Surgery, Inc., The General Hospital Corporation
    Inventors: Taylor W. Aronhalt, Lee M. Kaplan, Nicholas Stylopoulos, Jason L. Harris, Dwight Henninger, James W. Voegele, Mark S. Ortiz
  • Patent number: 10406362
    Abstract: Methods for treating polycystic ovarian syndrome with a neuromodulation device that modulates sympathetic neural activity are described herein. The neuromodulation device is an apparatus for the treatment of polycystic ovarian syndrome. In one aspect, the apparatus decreases the neural activity of a postganglionic ovary-innervating sympathetic nerve. Modulation in neural activity may be achieved using an apparatus comprising one or more stimulators each configured to apply a signal to a postganglionic ovary-innervating sympathetic nerve of the patient, a controller coupled to the one or more stimulators, the controller controlling the signal to be applied by each of the one or more stimulators, such that the signal decreases the neural activity of the nerve to produce a physiological and/or biochemical response in the patient, wherein the physiological and/or biochemical response comprises an improvement in one or more symptoms of polycystic ovarian syndrome.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: September 10, 2019
    Assignee: Galvani Bioeletronics Limited
    Inventors: Hans Jakob Kristoffer Famm, Hernan E. Lara, Victor Eugene Pikov, Arun Sridhar
  • Patent number: 10398488
    Abstract: An epicardial device, system, and method for stabilizing the left atrial appendage during a left atrial appendage ligation/occlusion procedure. A cryoadhesion device including a stabilization element is positioned within the pericardial space proximate the left atrial appendage through subxiphoid access. Once the stabilization element is in contact with the left atrial appendage, the stabilization element is cooled to a temperature that is sufficient to cryoadhere the stabilization element to the left atrial appendage. In this way, the cryoadhesion device stabilizes the left atrial appendage in order to perform left atrial appendage ligation/occlusion with a secondary medical device.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: September 3, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Nicolas Coulombe
  • Patent number: 10390872
    Abstract: An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: August 27, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Luc Pageard
  • Patent number: 10376678
    Abstract: A system for controlling reperfusion in a blood vessel of a patient including a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, the elongated member having a proximal portion and a distal portion, the elongated member configured for insertion so the distal portion extends distal of a clot in the blood vessel. A sensor is positioned at the distal portion of the elongated member for positioning distal of the blood clot, the sensor measuring a parameter of blood downstream of the clot. An indicator communicates with the sensor, the indicator indicating a measured parameter for insertion of an instrument for controlling blood flow.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 13, 2019
    Assignee: Makaha Medical, LLC.
    Inventor: Marc-Alan Levine
  • Patent number: 10379071
    Abstract: Apparatus is provided featuring a signal processor or processing module configured to: receive signaling containing information about at least two sensing modalities sensed by a single probe arranged in relation to a multiphase flow or process volume; and determine using a multiple modality tomographic analysis technique information about different fluid layers in the multiphase flow or process volume, based at least partly on the signaling received. The signal processor or processing module may be configured to provide corresponding signaling containing corresponding information about different fluid layers in the multiphase flow or process volume.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: August 13, 2019
    Assignee: CiDRA Corporate Services Inc.
    Inventors: Alan D. Kersey, Christian V. O'Keefe
  • Patent number: 10349998
    Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: July 16, 2019
    Assignee: Fractyl Laboratories, Inc.
    Inventors: Phillip S. Levin, Jay Caplan, Harith Rajagopalan, Mark A. Manasas, Andrew Coats, J. Christopher Flaherty
  • Patent number: 10342611
    Abstract: The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 9, 2019
    Assignee: Innoblative Designs, Inc.
    Inventor: Robert F. Rioux
  • Patent number: 10322248
    Abstract: A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 18, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Cagri Giray Besirli, Stephen Smith, Kevin P. Pipe, Gun-Ho Kim
  • Patent number: 10307200
    Abstract: Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: June 4, 2019
    Assignee: Arrinex, Inc.
    Inventor: Vahid Saadat
  • Patent number: 10251692
    Abstract: A system and method for determining the optimum dose of cryotreatment to an area of target tissue to achieve isolation based on the time to effect (TTE). The system may generally include a treatment device, a sensing device, and a processor programmed to calculate the optimum dose of cryotreatment, in seconds, based on TTE. The TTE may be based on electrical signals received by the processor from the sensing device. The processor may be further programmed to automatically terminate a cryoablation procedure when the optimum dose of cryotreatment has elapsed. The optimum dose of cryotreatment may be the time, in seconds, it takes to achieve isolation, which may be the time it takes for an area of tissue to reach approximately ?20° C.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: April 9, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10251693
    Abstract: An ablation assembly includes a handle, a catheter assembly and a connector locking assembly. The catheter assembly includes: a catheter shaft, a balloon and a connector at the distal and proximal ends of the catheter shaft, and a delivery tube extending between there between. The connector includes a connector body secured to the proximal end and a plug secured to the delivery tube, the plug and delivery tube movable axially and rotationally. The handle includes an open portion receiving the plug and the connector body. The connector locking assembly includes: means for simultaneously automatically connecting the plug and the connector body to the handle to place the connector in a load state prior to use, and means for automatically releasing the connector body and thereafter the plug from the handle to place the connector in an eject state to permit the connector to be removed from the handle.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: April 9, 2019
    Assignee: PENTAX OF AMERICA, INC.
    Inventors: Gabriel F. W. Newell, Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Byron Liehwah Chun, Dennis Franklin Burke
  • Patent number: 10231865
    Abstract: An apparatus for temperature controlling an endocavity such as the rectum during thermal therapy of nearby tissues is disclosed. In some aspects the apparatus is mechanically configured to best conform to the patient. In other aspects the apparatus is designed to eliminate gas bubbles from forming or accumulating in certain volumes that would interfere with the thermal therapy. In other aspects the apparatus is optimized for use in cooling the rectum during ultrasound thermal therapy of the prostate.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: March 19, 2019
    Assignee: Profound Medical Inc.
    Inventors: Owen Moffitt, Michael Wybenga
  • Patent number: 10213244
    Abstract: A cryogenic needle of a cryogenic system is coupled to a heater. While the needle is inserted into target tissue beneath skin, the heater provides heat to protect the skin. Power supplied to the heater is used to interpolate performance of the needle and/or operating parameters of the cryogenic system.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: February 26, 2019
    Assignee: Myoscience, Inc.
    Inventors: Michael Fourkas, Ronald Williams, John Allison, Jesse Rosen
  • Patent number: 10194934
    Abstract: A system for controlling temperature of a fluid used during treatment of biological tissue includes a fluid temperature control apparatus. The apparatus includes at least one heat transfer device and a solution bag and/or a heat transfer membrane. The solution bag and/or the heat transfer membrane reside in thermal communication with the heat transfer device. When the solution bag and/or the heat transfer membrane is fluidically coupled to an electrosurgical device, fluid is supplied to the electrosurgical device at a controlled temperature during a surgical procedure utilizing the electrosurgical device to enable more efficient treatment of the biological tissue. A corresponding method includes fluidically coupling the fluid temperature control apparatus to the electrosurgical device and supplying fluid at a controlled temperature during a surgical procedure utilizing the electrosurgical device to enable more efficient treatment of the biological tissue.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: February 5, 2019
    Assignee: Covidien LP
    Inventors: Steven P. Buysse, David N. Heard
  • Patent number: 10188444
    Abstract: A cryogenic needle probe having a proximal and distal region. A cooling supply tube provides pressurized cooling fluid within the needle. The proximal region is more conductive that the distal region. The proximal region is conductively coupled to a heat source.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: January 29, 2019
    Assignee: MyoScience, Inc.
    Inventors: Michael Fourkas, Ronald Williams, John Allison
  • Patent number: 10179065
    Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: January 15, 2019
    Assignee: NEURAXIS LLC
    Inventors: Michael Drnek, Dan Farley, John Sullivan
  • Patent number: 10130409
    Abstract: A method for cryogenically treating tissue. A connection is detected between a probe having a disposable secure processor (DSP) to a handpiece having a master control unit (MCU) and a handpiece secure processor (HSP), the probe having at least one cryogenic treatment applicator. The probe is fluidly coupled to a closed coolant supply system within the handpiece via the connection. An authentication process is initiated between the DSP and the HSP using the MCU. As a result of the authentication process, one of at least two predetermined results is determined, the at least two predetermined results being that the probe is authorized and non-authorized.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: November 20, 2018
    Assignee: Myoscience, Inc.
    Inventors: Corydon A. Hinton, Kyler Mikhail Connelly, Bijy Zachariah, Jesse Rosen
  • Patent number: 10098686
    Abstract: A cryogenic ablation catheter includes a catheter shaft, a balloon and a connector respectively at the catheter shaft proximal and distal ends, a refrigerant delivery tube assembly including a refrigerant delivery tube translatable within the catheter shaft lumen, and a refrigerant delivery element with an outlet located inside the balloon which directs refrigerant outwardly against the balloon at different axial positions as it translates. A cryogenic balloon ablation system includes the cryogenic ablation catheter, a catheter coupler mating with the connector, a linear motion assembly, and a connection line fluidly coupled to a refrigerant fluid source for supplying refrigerant fluid to the refrigerant delivery tube.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: October 16, 2018
    Assignee: PENTAX OF AMERICA, INC.
    Inventors: Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Richard S. Williams, Gabriel Francis W. Newell
  • Patent number: 10058312
    Abstract: A cryogenic medical system and method of use thereof for transseptal puncturing is disclosed, including a medical device having an elongate body with a fluid flow path therein, a thermally-transmissive region coupled to the elongate body in thermal communication with the fluid flow path, and a puncturing element movably coupled to the elongate body; and a cryogenic coolant source in fluid communication with the fluid flow path. The medical device may alternatively include an elongate body, a thermally-transmissive region coupled to the elongate body, a thermo-electric cooler in thermal communication with the thermally-transmissive region, and a puncturing element movably coupled to the elongate body.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: August 28, 2018
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10054341
    Abstract: A fluid heat exchanger has an impeller assembly with first and second impeller bodies mated together, each having a substantially circular shape and at least one opening therethrough. Impeller vanes extend axially from the first impeller body and away from the second impeller body. Impeller vanes extend axially from the second impeller body away from the first impeller body. A thermoelectric module is disposed between the first impeller body and the second impeller body. Heat sinks are connected to each side of the thermoelectric module and extend through at least one opening in the first and second impeller bodies, where the impeller vanes are configured to move a fluid through the heat sinks during rotation of the first and second impeller bodies. Electrically-conductive windings disposed in the impeller assembly are configured to deliver induced electric current to the thermoelectric module(s).
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: August 21, 2018
    Assignee: Ferrotec (USA) Corporation
    Inventors: Robert Otey, David A. Kaminski, Pheng Sin
  • Patent number: 10016229
    Abstract: A system for alleviating occipital neuralgia. The system has a needle probe having at least one needle. The at least one needle has a proximal end, a distal end, and a needle lumen therebetween, the needle configured for insertion proximate to a location of the occipital nerve. A cooling fluid supply lumen extends distally within the needle lumen to a distal portion of the needle lumen. A cooling fluid source is coupled to the cooling fluid supply lumen to direct cooling fluid flow into the needle lumen. A controller that has at least one processor configured implements an occipital neuralgia treatment algorithm for controlling the cooling fluid source so that liquid from the cooling flow vaporizes within the needle lumen to provide a treatment phase to location of the occipital nerve such that the occipital neuralgia is mitigated.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: July 10, 2018
    Assignee: Myoscience, Inc.
    Inventors: Clint Carnell, John Allison, Jwala Karnik, Jesse Rosen
  • Patent number: 9936997
    Abstract: A surgical instrument includes an outer shaft defining a passageway. An inner shaft is disposed within the passageway and defines a lumen. An expandable structure has a first end coupled to a second end of the outer shaft and a second end coupled to a second end of the inner shaft. The expandable member defines a chamber. A delivery shaft includes a first end positioned within the passageway and a second end positioned within the chamber. The delivery shaft defines a channel configured to deliver a coolant out of an opening in the second end of the delivery shaft and into the chamber to move the expandable structure from an unexpanded configuration to an expanded configuration. A variable exhaust valve is in communication with the passageway and is configured to regulate pressure within the chamber. Systems and methods are disclosed.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: April 10, 2018
    Assignee: Kyphon SÀRL
    Inventor: Stephen Nash
  • Patent number: 9936998
    Abstract: The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: April 10, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Dan Wittenberger, Marwan Abboud, Constantin Bogdan Ciobotaru, Ramin Sabbaghe-Kermani
  • Patent number: 9936999
    Abstract: A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 10, 2018
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9931152
    Abstract: A medical device includes a catheter body having a first injection lumen, a second injection lumen, and an exhaust lumen, where the first injection lumen provides a fluid flow rate greater than a fluid flow rate provided by the second injection lumen; an expandable element coupled to the catheter body in fluid communication with the first and second injection lumens; a cryogenic fluid source in fluid communication with the first and second injection lumens; a valve in fluid communication with the first and second injection lumens to selectively allow fluid flow to at least one of the first and second injection lumens; a pressure sensor in fluid communication with an interior defined by the expandable element; and a controller in communication with the pressure sensor programmed to regulate fluid flow through the first injection lumen based at least in part on a signal from the pressure sensor.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: April 3, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Dan Wittenberger, Claudia Lueckge, Miriam Lane
  • Patent number: 9931153
    Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may utilize a thermochemical reaction between at least two reagents where a first reagent has been preloaded into a catheter while a limiting reagent is circulated through the catheter to react with the first reagent. The resulting chemical reaction may be exothermic or endothermic, and a heat transfer fluid may be used to exchange energy between the chemical reaction and surrounding tissue.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: April 3, 2018
    Assignee: Spiration, Inc.
    Inventor: Christopher Thralls
  • Patent number: 9907610
    Abstract: Cardiac catheterization is conducted using a probe having a balloon assembly, in which a spring has a resting axially elongated configuration and a torsed, axially shortened configuration. An inflatable balloon is twisted about the spring and mechanically linked to the spring. A flexible sheath is disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber to contain a fluid flowing therein and thereout for inflation of the balloon and deflation of the balloon so as to energize and de-energize the spring.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: March 6, 2018
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Christopher Thomas Beeckler, Joseph Thomas Keyes, Rowan Olund Hettel
  • Patent number: 9888953
    Abstract: A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: February 13, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frank Ingle, Rebecca Tin, Robert F. Bencini, James Mazzone
  • Patent number: 9855089
    Abstract: A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: January 2, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Scott W. Davie
  • Patent number: 9820795
    Abstract: Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about ?15° C. to about ?30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: November 21, 2017
    Assignee: BERGER THERMAL RESEARCH LTD.
    Inventors: Abraham Berger, Avri Hazan
  • Patent number: 9814512
    Abstract: A medical device includes a steering element defining a passage for a guide wire. A fluid injection tube defining a proximal and a distal end is also included, wherein a portion of the fluid injection tube is contoured about a portion of the steering element. A plurality of injection ports may be disposed in the portion of the fluid injection tube contoured about the steering element.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: November 14, 2017
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Marwan Abboud, Teresa Ann Mihalik, Jean-Pierre Desmarais, Dan Wittenberger
  • Patent number: 9808303
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: November 7, 2017
    Assignee: Cibiem, Inc.
    Inventors: Eric Ryba, Mark Gelfand
  • Patent number: 9801676
    Abstract: A cryotherapy catheter can include an elongate member and an inflatable balloon at a distal end of the elongate member, the elongate member having lumens formed therein to supply cryogenic fluid to a chamber of the balloon and to channel exhaust from the balloon chamber; and a controller programmed to control a first rate at which the cryogenic fluid is supplied to the balloon chamber and a second rate at which exhaust is channeled from the balloon chamber, wherein the controller is programmed to a) develop, during a first phase of a cryotherapy procedure, a first pressure inside the balloon chamber at a value that is greater than an ambient pressure outside and adjacent to a proximal end of the elongate member, and b) develop, during a second phase of the cryotherapy procedure, the first pressure at a value that is less than the ambient pressure.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: October 31, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Leonard J. George, Joann Heberer