Internal Application Patents (Class 606/21)
  • Patent number: 10379071
    Abstract: Apparatus is provided featuring a signal processor or processing module configured to: receive signaling containing information about at least two sensing modalities sensed by a single probe arranged in relation to a multiphase flow or process volume; and determine using a multiple modality tomographic analysis technique information about different fluid layers in the multiphase flow or process volume, based at least partly on the signaling received. The signal processor or processing module may be configured to provide corresponding signaling containing corresponding information about different fluid layers in the multiphase flow or process volume.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: August 13, 2019
    Assignee: CiDRA Corporate Services Inc.
    Inventors: Alan D. Kersey, Christian V. O'Keefe
  • Patent number: 10376678
    Abstract: A system for controlling reperfusion in a blood vessel of a patient including a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, the elongated member having a proximal portion and a distal portion, the elongated member configured for insertion so the distal portion extends distal of a clot in the blood vessel. A sensor is positioned at the distal portion of the elongated member for positioning distal of the blood clot, the sensor measuring a parameter of blood downstream of the clot. An indicator communicates with the sensor, the indicator indicating a measured parameter for insertion of an instrument for controlling blood flow.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 13, 2019
    Assignee: Makaha Medical, LLC.
    Inventor: Marc-Alan Levine
  • Patent number: 10349998
    Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: July 16, 2019
    Assignee: Fractyl Laboratories, Inc.
    Inventors: Phillip S. Levin, Jay Caplan, Harith Rajagopalan, Mark A. Manasas, Andrew Coats, J. Christopher Flaherty
  • Patent number: 10342611
    Abstract: The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 9, 2019
    Assignee: Innoblative Designs, Inc.
    Inventor: Robert F. Rioux
  • Patent number: 10322248
    Abstract: A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 18, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Cagri Giray Besirli, Stephen Smith, Kevin P. Pipe, Gun-Ho Kim
  • Patent number: 10307200
    Abstract: Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: June 4, 2019
    Assignee: Arrinex, Inc.
    Inventor: Vahid Saadat
  • Patent number: 10251692
    Abstract: A system and method for determining the optimum dose of cryotreatment to an area of target tissue to achieve isolation based on the time to effect (TTE). The system may generally include a treatment device, a sensing device, and a processor programmed to calculate the optimum dose of cryotreatment, in seconds, based on TTE. The TTE may be based on electrical signals received by the processor from the sensing device. The processor may be further programmed to automatically terminate a cryoablation procedure when the optimum dose of cryotreatment has elapsed. The optimum dose of cryotreatment may be the time, in seconds, it takes to achieve isolation, which may be the time it takes for an area of tissue to reach approximately ?20° C.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: April 9, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10251693
    Abstract: An ablation assembly includes a handle, a catheter assembly and a connector locking assembly. The catheter assembly includes: a catheter shaft, a balloon and a connector at the distal and proximal ends of the catheter shaft, and a delivery tube extending between there between. The connector includes a connector body secured to the proximal end and a plug secured to the delivery tube, the plug and delivery tube movable axially and rotationally. The handle includes an open portion receiving the plug and the connector body. The connector locking assembly includes: means for simultaneously automatically connecting the plug and the connector body to the handle to place the connector in a load state prior to use, and means for automatically releasing the connector body and thereafter the plug from the handle to place the connector in an eject state to permit the connector to be removed from the handle.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: April 9, 2019
    Assignee: PENTAX OF AMERICA, INC.
    Inventors: Gabriel F. W. Newell, Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Byron Liehwah Chun, Dennis Franklin Burke
  • Patent number: 10231865
    Abstract: An apparatus for temperature controlling an endocavity such as the rectum during thermal therapy of nearby tissues is disclosed. In some aspects the apparatus is mechanically configured to best conform to the patient. In other aspects the apparatus is designed to eliminate gas bubbles from forming or accumulating in certain volumes that would interfere with the thermal therapy. In other aspects the apparatus is optimized for use in cooling the rectum during ultrasound thermal therapy of the prostate.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: March 19, 2019
    Assignee: Profound Medical Inc.
    Inventors: Owen Moffitt, Michael Wybenga
  • Patent number: 10213244
    Abstract: A cryogenic needle of a cryogenic system is coupled to a heater. While the needle is inserted into target tissue beneath skin, the heater provides heat to protect the skin. Power supplied to the heater is used to interpolate performance of the needle and/or operating parameters of the cryogenic system.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: February 26, 2019
    Assignee: Myoscience, Inc.
    Inventors: Michael Fourkas, Ronald Williams, John Allison, Jesse Rosen
  • Patent number: 10194934
    Abstract: A system for controlling temperature of a fluid used during treatment of biological tissue includes a fluid temperature control apparatus. The apparatus includes at least one heat transfer device and a solution bag and/or a heat transfer membrane. The solution bag and/or the heat transfer membrane reside in thermal communication with the heat transfer device. When the solution bag and/or the heat transfer membrane is fluidically coupled to an electrosurgical device, fluid is supplied to the electrosurgical device at a controlled temperature during a surgical procedure utilizing the electrosurgical device to enable more efficient treatment of the biological tissue. A corresponding method includes fluidically coupling the fluid temperature control apparatus to the electrosurgical device and supplying fluid at a controlled temperature during a surgical procedure utilizing the electrosurgical device to enable more efficient treatment of the biological tissue.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: February 5, 2019
    Assignee: Covidien LP
    Inventors: Steven P. Buysse, David N. Heard
  • Patent number: 10188444
    Abstract: A cryogenic needle probe having a proximal and distal region. A cooling supply tube provides pressurized cooling fluid within the needle. The proximal region is more conductive that the distal region. The proximal region is conductively coupled to a heat source.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: January 29, 2019
    Assignee: MyoScience, Inc.
    Inventors: Michael Fourkas, Ronald Williams, John Allison
  • Patent number: 10179065
    Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: January 15, 2019
    Assignee: NEURAXIS LLC
    Inventors: Michael Drnek, Dan Farley, John Sullivan
  • Patent number: 10130409
    Abstract: A method for cryogenically treating tissue. A connection is detected between a probe having a disposable secure processor (DSP) to a handpiece having a master control unit (MCU) and a handpiece secure processor (HSP), the probe having at least one cryogenic treatment applicator. The probe is fluidly coupled to a closed coolant supply system within the handpiece via the connection. An authentication process is initiated between the DSP and the HSP using the MCU. As a result of the authentication process, one of at least two predetermined results is determined, the at least two predetermined results being that the probe is authorized and non-authorized.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: November 20, 2018
    Assignee: Myoscience, Inc.
    Inventors: Corydon A. Hinton, Kyler Mikhail Connelly, Bijy Zachariah, Jesse Rosen
  • Patent number: 10098686
    Abstract: A cryogenic ablation catheter includes a catheter shaft, a balloon and a connector respectively at the catheter shaft proximal and distal ends, a refrigerant delivery tube assembly including a refrigerant delivery tube translatable within the catheter shaft lumen, and a refrigerant delivery element with an outlet located inside the balloon which directs refrigerant outwardly against the balloon at different axial positions as it translates. A cryogenic balloon ablation system includes the cryogenic ablation catheter, a catheter coupler mating with the connector, a linear motion assembly, and a connection line fluidly coupled to a refrigerant fluid source for supplying refrigerant fluid to the refrigerant delivery tube.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: October 16, 2018
    Assignee: PENTAX OF AMERICA, INC.
    Inventors: Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Richard S. Williams, Gabriel Francis W. Newell
  • Patent number: 10058312
    Abstract: A cryogenic medical system and method of use thereof for transseptal puncturing is disclosed, including a medical device having an elongate body with a fluid flow path therein, a thermally-transmissive region coupled to the elongate body in thermal communication with the fluid flow path, and a puncturing element movably coupled to the elongate body; and a cryogenic coolant source in fluid communication with the fluid flow path. The medical device may alternatively include an elongate body, a thermally-transmissive region coupled to the elongate body, a thermo-electric cooler in thermal communication with the thermally-transmissive region, and a puncturing element movably coupled to the elongate body.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: August 28, 2018
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10054341
    Abstract: A fluid heat exchanger has an impeller assembly with first and second impeller bodies mated together, each having a substantially circular shape and at least one opening therethrough. Impeller vanes extend axially from the first impeller body and away from the second impeller body. Impeller vanes extend axially from the second impeller body away from the first impeller body. A thermoelectric module is disposed between the first impeller body and the second impeller body. Heat sinks are connected to each side of the thermoelectric module and extend through at least one opening in the first and second impeller bodies, where the impeller vanes are configured to move a fluid through the heat sinks during rotation of the first and second impeller bodies. Electrically-conductive windings disposed in the impeller assembly are configured to deliver induced electric current to the thermoelectric module(s).
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: August 21, 2018
    Assignee: Ferrotec (USA) Corporation
    Inventors: Robert Otey, David A. Kaminski, Pheng Sin
  • Patent number: 10016229
    Abstract: A system for alleviating occipital neuralgia. The system has a needle probe having at least one needle. The at least one needle has a proximal end, a distal end, and a needle lumen therebetween, the needle configured for insertion proximate to a location of the occipital nerve. A cooling fluid supply lumen extends distally within the needle lumen to a distal portion of the needle lumen. A cooling fluid source is coupled to the cooling fluid supply lumen to direct cooling fluid flow into the needle lumen. A controller that has at least one processor configured implements an occipital neuralgia treatment algorithm for controlling the cooling fluid source so that liquid from the cooling flow vaporizes within the needle lumen to provide a treatment phase to location of the occipital nerve such that the occipital neuralgia is mitigated.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: July 10, 2018
    Assignee: Myoscience, Inc.
    Inventors: Clint Carnell, John Allison, Jwala Karnik, Jesse Rosen
  • Patent number: 9936999
    Abstract: A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 10, 2018
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9936997
    Abstract: A surgical instrument includes an outer shaft defining a passageway. An inner shaft is disposed within the passageway and defines a lumen. An expandable structure has a first end coupled to a second end of the outer shaft and a second end coupled to a second end of the inner shaft. The expandable member defines a chamber. A delivery shaft includes a first end positioned within the passageway and a second end positioned within the chamber. The delivery shaft defines a channel configured to deliver a coolant out of an opening in the second end of the delivery shaft and into the chamber to move the expandable structure from an unexpanded configuration to an expanded configuration. A variable exhaust valve is in communication with the passageway and is configured to regulate pressure within the chamber. Systems and methods are disclosed.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: April 10, 2018
    Assignee: Kyphon SÀRL
    Inventor: Stephen Nash
  • Patent number: 9936998
    Abstract: The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: April 10, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Dan Wittenberger, Marwan Abboud, Constantin Bogdan Ciobotaru, Ramin Sabbaghe-Kermani
  • Patent number: 9931152
    Abstract: A medical device includes a catheter body having a first injection lumen, a second injection lumen, and an exhaust lumen, where the first injection lumen provides a fluid flow rate greater than a fluid flow rate provided by the second injection lumen; an expandable element coupled to the catheter body in fluid communication with the first and second injection lumens; a cryogenic fluid source in fluid communication with the first and second injection lumens; a valve in fluid communication with the first and second injection lumens to selectively allow fluid flow to at least one of the first and second injection lumens; a pressure sensor in fluid communication with an interior defined by the expandable element; and a controller in communication with the pressure sensor programmed to regulate fluid flow through the first injection lumen based at least in part on a signal from the pressure sensor.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: April 3, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Dan Wittenberger, Claudia Lueckge, Miriam Lane
  • Patent number: 9931153
    Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may utilize a thermochemical reaction between at least two reagents where a first reagent has been preloaded into a catheter while a limiting reagent is circulated through the catheter to react with the first reagent. The resulting chemical reaction may be exothermic or endothermic, and a heat transfer fluid may be used to exchange energy between the chemical reaction and surrounding tissue.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: April 3, 2018
    Assignee: Spiration, Inc.
    Inventor: Christopher Thralls
  • Patent number: 9907610
    Abstract: Cardiac catheterization is conducted using a probe having a balloon assembly, in which a spring has a resting axially elongated configuration and a torsed, axially shortened configuration. An inflatable balloon is twisted about the spring and mechanically linked to the spring. A flexible sheath is disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber to contain a fluid flowing therein and thereout for inflation of the balloon and deflation of the balloon so as to energize and de-energize the spring.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: March 6, 2018
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Christopher Thomas Beeckler, Joseph Thomas Keyes, Rowan Olund Hettel
  • Patent number: 9888953
    Abstract: A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: February 13, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frank Ingle, Rebecca Tin, Robert F. Bencini, James Mazzone
  • Patent number: 9855089
    Abstract: A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: January 2, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Scott W. Davie
  • Patent number: 9820795
    Abstract: Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about ?15° C. to about ?30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: November 21, 2017
    Assignee: BERGER THERMAL RESEARCH LTD.
    Inventors: Abraham Berger, Avri Hazan
  • Patent number: 9814512
    Abstract: A medical device includes a steering element defining a passage for a guide wire. A fluid injection tube defining a proximal and a distal end is also included, wherein a portion of the fluid injection tube is contoured about a portion of the steering element. A plurality of injection ports may be disposed in the portion of the fluid injection tube contoured about the steering element.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: November 14, 2017
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Marwan Abboud, Teresa Ann Mihalik, Jean-Pierre Desmarais, Dan Wittenberger
  • Patent number: 9808303
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: November 7, 2017
    Assignee: Cibiem, Inc.
    Inventors: Eric Ryba, Mark Gelfand
  • Patent number: 9801676
    Abstract: A cryotherapy catheter can include an elongate member and an inflatable balloon at a distal end of the elongate member, the elongate member having lumens formed therein to supply cryogenic fluid to a chamber of the balloon and to channel exhaust from the balloon chamber; and a controller programmed to control a first rate at which the cryogenic fluid is supplied to the balloon chamber and a second rate at which exhaust is channeled from the balloon chamber, wherein the controller is programmed to a) develop, during a first phase of a cryotherapy procedure, a first pressure inside the balloon chamber at a value that is greater than an ambient pressure outside and adjacent to a proximal end of the elongate member, and b) develop, during a second phase of the cryotherapy procedure, the first pressure at a value that is less than the ambient pressure.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: October 31, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Leonard J. George, Joann Heberer
  • Patent number: 9795433
    Abstract: The present invention provides a medical device having an elongate body with both a proximal end and a distal end, wherein the elongate body defines an intake lumen and an exhaust lumen. The medical device also has a first pliable element defining a cooling chamber disposed at a point along the elongate body, with the cooling chamber being in fluid communication with the intake lumen and the exhaust lumen. A second pliable element is provided which at least partially encloses the first pliable element, thereby defining a junction between the first and second pliable element. A check valve is included which is in fluid communication with the junction between the first pliable element and second pliable element, the valve further being in fluid communication with the exhaust lumen. Additionally, the medical device may include sensors or other monitoring means in fluid communication with the junction and the cooling chamber.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: October 24, 2017
    Assignee: Medtronic CryoCath LP
    Inventors: Marwan Abboud, Rachid Mahrouche, Teresa Ann Mihalik, Chadi Harmouche, Jean-Luc Pageard, John W. Lehmann
  • Patent number: 9757178
    Abstract: A cryoablation catheter assembly includes a catheter that defines at least one coolant outtake region and receives a rotatable guide tube and a coolant transfer tube. The coolant transfer tube receives and transfers coolant from a coolant source to a distal end of the coolant transfer tube. An expansion element is coupled to a distal portion of the catheter and defines an inner expansion-element space. The inner expansion-element space is in fluid communication with the at least one coolant outtake region and the distal end of the coolant transfer tube. A distal end of the expansion element couples to the guide tube. A rotation system is coupleable to, or coupled to, a proximal end of the guide tube and rotates the distal end of the expansion element relative to the proximal end of the expansion element by rotating the guide tube relative to the catheter.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: September 12, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Byron Chun
  • Patent number: 9750421
    Abstract: Devices and methods are provided for performing procedure on tissue with flow monitoring using flow sensors. The devices include an elongated member, and at least one flow sensor disposed on the elongated member. The flow sensor includes at least one temperature sensor and at least one heating element having a cavity. At least a portion of the at least one temperature sensor is housed in the cavity. A temperature measurement of the temperature sensor provides an indication of the flow rate of a fluid proximate to the flow sensor.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: September 5, 2017
    Assignee: MC10, Inc.
    Inventors: Roozbeh Ghaffari, Stephen Lee, John Work, John A. Wright, Jr., Lauren Klinker
  • Patent number: 9747684
    Abstract: In planning an ablation procedure, a planned target volume (PTV) is imported, which is typically selected by a doctor but may be computer identified. An initial set of candidate ablation regions that covers the PTV is computed. Ablation probe trajectories that avoid critical structures are computed to provide surgical 5 options for safe entry points and angles. An optimization component determines a minimum number of ablation regions, which fully covers the PTV, and generates locations and orientations for each ablation. A tracking system can be given these ablation targets, enabling the surgeon to control the probe more precisely to the desired location.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: August 29, 2017
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Karen I. Trovato, Douglas Summers-Stay
  • Patent number: 9700364
    Abstract: A cryogenic ablation catheter includes a catheter shaft, a balloon and a connector respectively at the catheter shaft proximal and distal ends, a refrigerant delivery tube assembly including a refrigerant delivery tube rotatable within the catheter shaft lumen, and a refrigerant delivery element with an outlet located inside the balloon which directs refrigerant outwardly against the balloon at different rotary positions as it rotates. A cryogenic balloon ablation system includes the cryogenic ablation catheter, a catheter coupler mating with the connector, a motor including a rotatable hollow motor shaft, and a delivery line fluidly coupled to a cryogenic gas source for supplying cryogenic gas to the refrigerant delivery tube. At least one of the refrigerant delivery tube and the delivery line passes at least partway through the hollow motor shaft. The coupling tip of the connector and the refrigerant delivery tube rotate with the motor shaft.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: July 11, 2017
    Assignee: C2 Therapeutics, Inc.
    Inventors: Gabriel Francis Wilgus Newell, Timothy Douglas Holland, Cesar Abalos Ico, Patrick Peichen Wu, Richard Steven Williams
  • Patent number: 9655667
    Abstract: Described herein are methods and devices for performing ablation via a cryoablation catheter. An ablation catheter having a cyroablation chamber at its distal end can be used to achieve a uniform ablation band in or around the pulmonary veins. The cyrochamber can house a dispersion member in fluid communication with a refrigerant supply and can function to evenly distribute received refrigerant over some portion of the inner wall of the cryochamber. As a result of this even distribution of refrigerant within the cyrochamber, uniform ablation of the targeted tissue of the patient can be achieved.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: May 23, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Raphael Hon
  • Patent number: 9646745
    Abstract: A thermistor assembly according to an exemplary aspect of the present disclosure includes, among other things, an elastomeric body, a thermistor housed at least partially inside the elastomeric body and a thermistor tip that protrudes outside of the elastomeric body.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: May 9, 2017
    Assignee: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Vedat Haydin, Deborah E. Callicoat, Francisco Fernandez, Brian Utley
  • Patent number: 9622680
    Abstract: An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of sensing elements disposed on the flexible substrate. The plurality of sensing elements are disposed about the inflatable body such that the sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: April 18, 2017
    Assignee: MC10, Inc.
    Inventors: Roozbeh Ghaffari, Robert D'Angelo, Bassel De Graff, Kevin Dowling, Yung-Yu Hsu, Lauren E. Klinker, Stephen P. Lee, Cliff Liu
  • Patent number: 9568918
    Abstract: The present disclosure relates to a balloon system that includes a flexible volume balloon hull configured to contain a lifting gas, a flexible volume ballonet contained within said balloon hull configured to contain a refrigerant gas and a refrigerant gas transfer device in fluid communication with the ballonet to control the balloon's vertical ascent and descent.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: February 14, 2017
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventor: William D. Perry
  • Patent number: 9554842
    Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: January 31, 2017
    Assignee: Sanarus Technologies, Inc.
    Inventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
  • Patent number: 9555223
    Abstract: A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: January 31, 2017
    Assignee: Medtronic CryoCath LP
    Inventors: Marwan Abboud, Rachid Mahrouche
  • Patent number: 9498274
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 22, 2016
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9492218
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 15, 2016
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9492216
    Abstract: A handle for an ablation device, the handle comprising a positioning control handle part adapted to be coupled to a positioning catheter of the ablation device and adapted to position the positioning catheter in an object, and an ablation control handle part adapted to be coupled to an ablation catheter of the ablation device and adapted to ablate material of the object using the ablation catheter, wherein the positioning control handle part and the ablation control handle part are adapted to be separable from one another.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: November 15, 2016
    Assignee: Afreeze GmbH
    Inventors: Gerald Fischer, Florian Hintringer, Martin Goll
  • Patent number: 9492217
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 15, 2016
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9486267
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: November 8, 2016
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9445859
    Abstract: An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: September 20, 2016
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Luc Pageard
  • Patent number: 9439707
    Abstract: A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: September 13, 2016
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9414878
    Abstract: A cryogenic ablation catheter includes a catheter shaft, a balloon and a connector respectively at the catheter shaft proximal and distal ends, a refrigerant delivery tube assembly including a refrigerant delivery tube translatable within the catheter shaft lumen, and a refrigerant delivery element with an outlet located inside the balloon which directs refrigerant outwardly against the balloon at different axial positions as it translates. A cryogenic balloon ablation system includes the cryogenic ablation catheter, a catheter coupler mating with the connector, a linear motion assembly, and a connection line fluidly coupled to a refrigerant fluid source for supplying refrigerant fluid to the refrigerant delivery tube.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: August 16, 2016
    Assignee: C2 Therapeutics, Inc.
    Inventors: Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Richard S. Williams, Gabriel Francis W. Newell
  • Patent number: 9345529
    Abstract: A method and system for cryotreatment of target tissue using a cryotreatment catheter through which a mapping catheter may be freely movable, even during activation of the cryotreatment element. The cryotreatment system may include a cryotreatment catheter, a mapping catheter slidably disposed within a lumen of the cryotreatment catheter, and one or more heating elements. The one or more heating elements may be disposed on the mapping catheter or within the lumen of the cryotreatment catheter. Activation of the one or more heating elements prevents the freezing of, or thaws, fluid within the lumen of the cryotreatment device when one or more cryotreatment elements are activated. The lack of frozen fluid within the lumen allows the mapping catheter to freely move within the cryotreatment catheter during a cryotreatment procedure, so that the mapping catheter may be positioned proximate the treatment site after initiation of cryotreatment.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: May 24, 2016
    Assignee: Medtronic CryoCath LP
    Inventor: Teresa Ann Mihalik