Internal Application Patents (Class 606/21)
  • Patent number: 11213338
    Abstract: A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: January 4, 2022
    Assignee: Aegea Medical Inc.
    Inventors: Hugh R. Sharkey, Ramiro Reyes, Kurt D. Sparks
  • Patent number: 11207117
    Abstract: The present disclosure relates generally to the field of cryotherapy. In particular, the present disclosure relates to cryotherapy systems that ensure egress of cryogen gas delivered within a patient's body during cryotherapy procedures and, more particularly, sensors for use with cryotherapy systems that include delivery catheters wherein the systems ensure that egress of cryogen gas from the patient's body is possible whenever the catheter is operating.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: December 28, 2021
    Assignee: CSA Medical, Inc.
    Inventors: Sean A. McDermott, Charles J. Vadala, Brian M. Hanley, John P. O'Connor
  • Patent number: 11154351
    Abstract: Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.
    Type: Grant
    Filed: November 14, 2015
    Date of Patent: October 26, 2021
    Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
    Inventors: Martin Rothman, Paul Coates
  • Patent number: 11141209
    Abstract: A method and system for providing lesion depth feedback during an ablation procedure. In particular, the method and system provide feedback data or information relating to lesion depth in myocardial tissue during a cryoablation procedure. A plurality of tissue temperature measurements may be transmitted from a plurality of thermocouples disposed on a cryotreatment element, which measurements may be used to determine a slope of change in temperature sensed by each thermocouple over time. The circulation of coolant through the treatment element may be adjusted when the slope changes. A change in slope may indicate that the cryoablation temperatures have passed through target myocardial tissue into non-target, non-myocardial tissue, which may result in collateral damage to structures near the heart.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: October 12, 2021
    Inventors: Jean-Pierre Lalonde, Regina E. Groves, Timothy G. Laske, Paul A. Iaizzo, John C. Bischof
  • Patent number: 11103296
    Abstract: An ablation applicator for an ablation device for ablating tissue of a blood vessel having a tubular body defining an inner lumen to which an ablation medium is conductable, a control mechanism for converting the tubular body between a passive operation mode for inserting the ablation applicator into the blood vessel and an active operation mode for ablating tissue of the blood vessel, and an ablation medium supply line for supplying the ablation medium to the inner lumen and positioned within the inner lumen and having a number of openings for passing the ablation medium from the ablation medium supply line to the inner lumen for thermally contacting the ablation medium with the tubular body wherein at least some of the openings are distributed along the ablation medium supply line with a predetermined spacing between neighboring openings.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: August 31, 2021
    Assignee: Afreeze GmbH
    Inventors: Gerald Fischer, Florian Hintringer
  • Patent number: 11089961
    Abstract: Embodiments of a system can include a temperature monitoring device including: a heat flux channel, a first temperature sensor thermally coupled to the heat flux channel, a second temperature sensor thermally coupled to the heat flux channel, a thermal cage thermally coupled to and arranged around the heat flux channel along a length of the heat flux channel, and a processing system operable to determine a core body temperature measurement based on temperature data collected at the first and the second temperature sensors.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: August 17, 2021
    Inventor: James Foody
  • Patent number: 11045245
    Abstract: A cryotreatment catheter for treating tissue. The catheter may include an outer elongate body, a balloon treatment element coupled to the distal portion of the elongate body with a plurality of balloon lobes radially arranged around the outer elongate body, an inner elongate body rotatably movable within the lumen of the outer elongate body, and a fluid delivery lumen located within the lumen of the outer elongate body and at least partially within the lumen of the inner elongate body. The fluid delivery lumen may be branched at a distal portion into a plurality of linear segments, each linear segment being in fluid communication with one of the plurality of balloon lobes. Each of the balloon lobes may be inflated independently of each other by the linear segments of the fluid delivery lumen.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: June 29, 2021
    Inventors: Rahmani Sara, Lies Safar Remali
  • Patent number: 11026739
    Abstract: The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: June 8, 2021
    Assignee: Medronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Dan Wittenberger, Marwan Abboud, Constantin Bogdan Ciobotaru, Ramin Sabbaghe-Kermani
  • Patent number: 11020163
    Abstract: A surgical instrument includes an outer shaft defining a passageway. An inner shaft is disposed within the passageway and defines a lumen. An expandable structure has a first end coupled to a second end of the outer shaft and a second end coupled to a second end of the inner shaft. The expandable member defines a chamber. A delivery shaft includes a first end positioned within the passageway and a second end positioned within the chamber. The delivery shaft defines a channel configured to deliver a coolant out of an opening in the second end of the delivery shaft and into the chamber to move the expandable structure from an unexpanded configuration to an expanded configuration. A variable exhaust valve is in communication with the passageway and is configured to regulate pressure within the chamber. Systems and methods are disclosed.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: June 1, 2021
    Assignee: MEDTRONIC HOLDING COMPANY SARL
    Inventor: Stephen Nash
  • Patent number: 11007078
    Abstract: An apparatus includes a shaft having a proximal end and a distal end; a stem extending from the distal end of the shaft and comprising a first cover and a second cover, the first cover and the second cover being configured to inhibit access to fallopian tubes of a patient; and a plurality of temperature sensors disposed on the shaft and on the stem. At least one of the temperature sensors is positioned between the proximal end of the shaft and the distal end of the shaft and at least one of the temperature sensors is positioned on the stem.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: May 18, 2021
    Assignee: Gyrus Acmi, Inc.
    Inventor: Nikhil Murdeshwar
  • Patent number: 10952792
    Abstract: Provided herein are devices, systems, and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, devices, systems, and methods are provided for delivering energy to difficult to access tissue regions (e.g. central or peripheral lung tissues), and/or reducing the amount of undesired heat given off during energy delivery.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: March 23, 2021
    Assignee: Neuwave Medical, Inc.
    Inventors: Matthew Thiel, Mark Thom, Richard W. Schefelker, Jeff Bissing, Yaniv Lazimy, Matt Schaning, Dave Anderson
  • Patent number: 10946179
    Abstract: The invention disclosed herein is a gastrostomy tube reinsertion device. The present invention provides a dilation device for dilating the gastrostomy tube tract in living tissues. In one aspect, the gastrostomy tube reinsertion device comprises multiple dilators to open collapsed soft tissue within the gastrostomy tube tract. Such device is useful for reinserting a gastrostomy tube into the previously defined tract in a human body, even after partial closure of the tract and gastrostomy tube insertion site. In another aspect, the present invention provides the method or steps for reinserting a gastrostomy tube into a patient.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: March 16, 2021
    Inventor: Adolfo Napolez
  • Patent number: 10932853
    Abstract: A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: March 2, 2021
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10905490
    Abstract: Cryotherapeutic devices for renal neuromodulation and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having a distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator having a distributor in fluid communication with the supply lumen and a balloon configured to deliver cryotherapeutic cooling to nerves proximate the treatment site when the cooling assembly is in a deployed state.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: February 2, 2021
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Benjamin J. Clark, David J. Hobbins, Tim Huynh, Grace Kelly, Brian Kelly
  • Patent number: 10893819
    Abstract: A system and method for Brugada syndrome epicardial ablation comprising preparing an endocardial duration map; preparing a baseline epicardial duration map comprising at least one or more areas of delimination; and when some of the areas of delimination are greater than 200 ms, performing epicardial ablation of the areas of delimination greater than 200 ms. The method may further comprise preparing an updated epicardial duration map after performing epicardial ablation, and determining whether or not a BrS pattern appears in the updated epicardial duration map; and when the BrS pattern appears, performing epicardial ablation. The method may further comprise preparing an updated epicardial duration map after performing epicardial ablation, and determining whether or not an abnormal EGM exists in the updated epicardial duration map; and when the abnormal EGM exists, performing epicardial ablation.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: January 19, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Carlo Pappone, Aharon Turgeman, Paolo Roberto Pozzi, Andrea Natalizia
  • Patent number: 10888377
    Abstract: The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: January 12, 2021
    Assignee: DIGMA MEDICAL LTD.
    Inventors: Ilan Ben-Oren, Avia Herschkovitz, Tamir Wolf, Irit Yaniv
  • Patent number: 10869779
    Abstract: Embodiments include methods and systems for treating joint pain associated with a nerve. A needle of a cryogenic system may be inserted beneath a skin surface. The needle may include an electrically conducting structure at least partially surrounded by an electrical insulator for conducting electrical energy. The needle may include an outer lumen and an inner lumen extending distally within the outer lumen, the inner lumen include a distal opening open to the outer lumen. The needle may be positioned at a desired location in proximity to the nerve, and a cooling therapy including cooling cycles and thawing periods may be performed to cool tissue at the desired location. The cooling therapy may sufficiently reduce the joint pain.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: December 22, 2020
    Assignee: Pacira CryoTech, Inc.
    Inventors: Keith Burger, Lisa Elkins, Ronald Williams
  • Patent number: 10864112
    Abstract: Embodiments include methods and systems for treating back pain associated with a nerve. A needle of a cryogenic system may be inserted beneath a skin surface. The needle may include an electrically conducting structure at least partially surrounded by an electrical insulator for conducting electrical energy. The needle may include an outer lumen and an inner lumen extending distally within the outer lumen, the inner lumen include a distal opening open to the outer lumen. The needle may be positioned at a desired location in proximity to the nerve, and a cooling therapy including cooling cycles and thawing periods may be performed to cool tissue at the desired location. The cooling therapy may sufficiently reduce the back pain.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: December 15, 2020
    Assignee: Pacira CryoTech, Inc.
    Inventors: Keith Burger, Lisa Elkins, Ronald Williams
  • Patent number: 10847778
    Abstract: A cooling lance is provided to cool an electrically conductive contact body. The cooling lance includes a lance body, a fluid line extending through the lance body, and a flexible cooling bladder positioned on an end of the lance body and in fluidic communication with the fluid line.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: November 24, 2020
    Assignee: TE Connectivity Germany GmbH
    Inventors: Andre Martin Dressel, Gerzson Toth, Rudi Blumenschein, Frank Kaehny
  • Patent number: 10828099
    Abstract: Cardiac catheterization is conducted using a probe having a balloon assembly, in which a spring has a resting axially elongated configuration and a torsed, axially shortened configuration. A balloon is twisted about the spring and mechanically linked to the spring. A flexible sheath is disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber to contain a fluid flowing therein and thereout of the balloon.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: November 10, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Christopher Thomas Beeckler, Joseph Thomas Keyes, Rowan Olund Hettel
  • Patent number: 10786296
    Abstract: A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: September 29, 2020
    Assignee: Medtronic CryoCath LP
    Inventors: Jean-Pierre Lalonde, Scott W. Davie
  • Patent number: 10758292
    Abstract: A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: September 1, 2020
    Assignee: AEGEA MEDICAL INC.
    Inventors: Hugh R. Sharkey, Ramiro Reyes, Kurt D. Sparks
  • Patent number: 10695041
    Abstract: A positioning device is configured to selectively position or otherwise manipulate one or more organs within the body of a subject. The positioning device includes a shaped expandable element that is configured to be selectively transitioned between an unexpanded, or collapsed, state and an expanded state. While in the expanded state, the expandable element repositions or otherwise manipulates an organ. Systems that include positioning devices are also disclosed, as are methods for positioning or otherwise manipulating organs.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 30, 2020
    Assignee: Manual Surgical Sciences LLC
    Inventor: Shawn P. Fojtik
  • Patent number: 10695126
    Abstract: Ablation catheters and systems include coaxial catheter shafts with an inner lumen for delivering an ablative agent and an outer lumen for circulation of a cooling element about the catheter. Induction heating is used to heat a chamber and vaporize a fluid within by wrapping a coil about a ferromagnetic chamber and providing an alternating current to the coil. A magnetic field is created in the area surrounding the chamber which induces electric current flow in the chamber, heating the chamber and vaporizing the fluid inside. Positioning elements help maintain the device in the proper position with respect to the target tissue and also prevent the passage of ablative agent to normal tissues.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: June 30, 2020
    Inventor: Virender K. Sharma
  • Patent number: 10682170
    Abstract: An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 16, 2020
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Luc Pageard
  • Patent number: 10667854
    Abstract: An endovascular near critical fluid based cryoablation catheter for creating an elongated lengthwise-continuous lesion in tissue can comprise an elongated shaft, a flexible distal tissue treatment section, and a distal tip. A plurality of flexible tubes can extend through the distal treatment section to transport a near critical fluid to and from the distal tip. The distal treatment section can also include a flexible fluid-sealed cover or barrier layer surrounding the delivery tubes. The cover and tubes can collectively define a space which is filled with a fluidic thermally conductive media. The thermally conductive media, fluid delivery tubes, and the cover can be arranged such that a flow of the near critical fluid through the tube bundle transfers heat between a target tissue and the distal treatment section of the catheter thereby creating the elongated lengthwise-continuous lesion in the tissue.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: June 2, 2020
    Assignee: Adagio Medical, Inc.
    Inventors: Alexei V. Babkin, Steven W. Kovalcheck, Xiaoyu Yu
  • Patent number: 10636324
    Abstract: Training device for training tracheal suctioning. The training device includes a tracheal core adapted to be arranged within a tracheal, nasal or oral cavity of a medical training simulator, and coupled to the airways of the simulator and an insert adapted to be inserted into the core, the insert forming a reservoir for simulated mucus.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: April 28, 2020
    Assignee: Laerdal Medical AS
    Inventors: Greg Necessary, Ben Tedeschi, Paul Griffith, David Thane
  • Patent number: 10610280
    Abstract: The embodied invention is a method of removing intraperitoneal fat by using a freezing cryoprobe and inserting it into the abdominal cavity. The freezing cryoprobe is covered by a vacuum sleeve which provides for a method for abdominal fat removal once the cells are damaged. A multi-step surgical procedure is used to freeze, irrigate, and remove the destroyed fat tissue. Also, an ultrasonic transmitter is inserted into an outer cryoprobe sheath to assess organ position with the advantage of an internal transmitter which greatly aids in organ identification.
    Type: Grant
    Filed: February 2, 2019
    Date of Patent: April 7, 2020
    Inventor: Ayad K. M. Agha
  • Patent number: 10596030
    Abstract: A method in which a location is determined on the skin that is proximate to a sensory nerve that is associated with a painful condition. At least one needle of a cryogenic device is inserted into the location on the skin such that the needle is proximate to the sensory nerve. The device is activated such that the at least one needle creates a cooling zone about the sensory nerve, thereby eliminating or reducing severity of the painful condition.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: March 24, 2020
    Assignee: Pacira CryoTech, Inc.
    Inventors: Jwala Karnik, Jason Reynolds, John Allison, Clint Carnell
  • Patent number: 10588682
    Abstract: Embodiments related to cryogenically ablating a portion of the inner surface of a vessel by constraining a cryoballoon using various apparatuses and methods are disclosed. For example, a catheter can include a cryoballoon for ablation of the vessel wall and a constraining element disposed substantially in parallel with the cryoballoon to deflect or offset a portion of the cryoballoon away from non-target tissue of the vessel wall and prevent ablation of the non-target tissue. Partial circumferential, non-continuous, or helical ablation can be effective for treating a variety of renal, cardio-renal, and other diseases including but not limited to hypertension, heart failure, renal disease, renal failure, contrast nephropathy, arrhythmia, and myocardial infarction. The constraining element may be, for example, a second inflatable balloon or one or more self-expanding prongs.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: March 17, 2020
    Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
    Inventors: Brian Kelly, John Kelly, Gary P. Kelly, Barry Mullins
  • Patent number: 10512460
    Abstract: A system (10) including an helicoidal member (16); an elongated guide (26) positionable at least partially through the helicoidal member (16) along the longitudinal axis of helicoidal member (16), the guide (26) defining a longitudinally extending peripheral surface cooled portion (32); a cooling subsystem (33) for cooling the peripheral surface cooled portion (32); and a driver (34) for mounting the helicoidal member (16) thereto and rotating the helicoidal member (16) along the helicoidal member longitudinal axis while allowing the helicoidal member (16) to advance along the guide (26) in a distally oriented direction.
    Type: Grant
    Filed: December 19, 2015
    Date of Patent: December 24, 2019
    Inventors: Toufic Azar, Renzo Cecere
  • Patent number: 10478633
    Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 19, 2019
    Assignee: BTL Medical Technologies S.R.O.
    Inventors: Tomás Schwarz, Ondra Prouza
  • Patent number: 10471269
    Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 12, 2019
    Assignee: BTL Medical Technologies S.R.O.
    Inventors: Tomás Schwarz, Ondra Prouza
  • Patent number: 10456185
    Abstract: A method for reshaping a nasal airway in a patient involves advancing an inflatable balloon of a reshaping device in an uninflated configuration into a nostril of the patient and between a nasal septum and a lateral wall of the nasal airway. The method then involves inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to contact nasal mucosa covering the nasal septum and the lateral wall, delivering energy from an energy delivery member attached to or inside of the inflatable balloon, and removing the reshaping device from the nasal airway.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: October 29, 2019
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10441338
    Abstract: A system and method for creating radial-linear lesions in tissue. The system includes a cryoablation device having a first balloon, a second balloon disposed about the first balloon, and one or more splines disposed between the first balloon and second balloon, each spline defining a plurality of ports. The splines may be in communication with a coolant supply, and the first balloon may be in communication with a coolant supply or non-coolant inflation fluid supply. When the first balloon is in the uninflated configuration, the splines may have a substantially linear configuration. Each of the splines may be radially oriented about an elongate shaft and transitionable between the substantially linear configuration and an arcuate configuration when the first balloon is in the inflated configuration. Coolant expelled from the splines between the first and second balloons creates an ablation pattern on the outer surface of the second balloon.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: October 15, 2019
    Assignee: Medtronic CryoCath LP
    Inventors: George D. Mallin, Claudia Lueckge
  • Patent number: 10441339
    Abstract: Flexible apparatus for ablating unhealthy spinal tissue. A housing includes a distal end and a proximal end. Multiple thermocouples mounted on the housing measure spinal tissue temperatures at locations between the proximal end and the distal end. A sensor measures spinal tissue impedance. The measured spinal tissue impedance corresponds to various physical state data of the spinal tissue. The spinal tissue impedance and the spinal tissue temperatures are displayed to the surgeon, enabling the surgeon to determine with certainty the location of the unhealthy spinal tissue, and to exercise control over the ablation apparatus. Nerve stimulation by IMP/STM switch system to detect nerve responses before and after treatment.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: October 15, 2019
    Assignee: Medtronic Holding Company Sárl
    Inventors: Stephen W. Lee, Michael A. Smith, Dawud F. Dueiri
  • Patent number: 10441459
    Abstract: Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: October 15, 2019
    Assignees: Ethicon Endo-Surgery, Inc., The General Hospital Corporation
    Inventors: Taylor W. Aronhalt, Lee M. Kaplan, Nicholas Stylopoulos, Jason L. Harris, Dwight Henninger, James W. Voegele, Mark S. Ortiz
  • Patent number: 10406362
    Abstract: Methods for treating polycystic ovarian syndrome with a neuromodulation device that modulates sympathetic neural activity are described herein. The neuromodulation device is an apparatus for the treatment of polycystic ovarian syndrome. In one aspect, the apparatus decreases the neural activity of a postganglionic ovary-innervating sympathetic nerve. Modulation in neural activity may be achieved using an apparatus comprising one or more stimulators each configured to apply a signal to a postganglionic ovary-innervating sympathetic nerve of the patient, a controller coupled to the one or more stimulators, the controller controlling the signal to be applied by each of the one or more stimulators, such that the signal decreases the neural activity of the nerve to produce a physiological and/or biochemical response in the patient, wherein the physiological and/or biochemical response comprises an improvement in one or more symptoms of polycystic ovarian syndrome.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: September 10, 2019
    Assignee: Galvani Bioeletronics Limited
    Inventors: Hans Jakob Kristoffer Famm, Hernan E. Lara, Victor Eugene Pikov, Arun Sridhar
  • Patent number: 10398488
    Abstract: An epicardial device, system, and method for stabilizing the left atrial appendage during a left atrial appendage ligation/occlusion procedure. A cryoadhesion device including a stabilization element is positioned within the pericardial space proximate the left atrial appendage through subxiphoid access. Once the stabilization element is in contact with the left atrial appendage, the stabilization element is cooled to a temperature that is sufficient to cryoadhere the stabilization element to the left atrial appendage. In this way, the cryoadhesion device stabilizes the left atrial appendage in order to perform left atrial appendage ligation/occlusion with a secondary medical device.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: September 3, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Nicolas Coulombe
  • Patent number: 10390872
    Abstract: An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: August 27, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Luc Pageard
  • Patent number: 10376678
    Abstract: A system for controlling reperfusion in a blood vessel of a patient including a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, the elongated member having a proximal portion and a distal portion, the elongated member configured for insertion so the distal portion extends distal of a clot in the blood vessel. A sensor is positioned at the distal portion of the elongated member for positioning distal of the blood clot, the sensor measuring a parameter of blood downstream of the clot. An indicator communicates with the sensor, the indicator indicating a measured parameter for insertion of an instrument for controlling blood flow.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 13, 2019
    Assignee: Makaha Medical, LLC.
    Inventor: Marc-Alan Levine
  • Patent number: 10379071
    Abstract: Apparatus is provided featuring a signal processor or processing module configured to: receive signaling containing information about at least two sensing modalities sensed by a single probe arranged in relation to a multiphase flow or process volume; and determine using a multiple modality tomographic analysis technique information about different fluid layers in the multiphase flow or process volume, based at least partly on the signaling received. The signal processor or processing module may be configured to provide corresponding signaling containing corresponding information about different fluid layers in the multiphase flow or process volume.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: August 13, 2019
    Assignee: CiDRA Corporate Services Inc.
    Inventors: Alan D. Kersey, Christian V. O'Keefe
  • Patent number: 10349998
    Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: July 16, 2019
    Assignee: Fractyl Laboratories, Inc.
    Inventors: Phillip S. Levin, Jay Caplan, Harith Rajagopalan, Mark A. Manasas, Andrew Coats, J. Christopher Flaherty
  • Patent number: 10342611
    Abstract: The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 9, 2019
    Assignee: Innoblative Designs, Inc.
    Inventor: Robert F. Rioux
  • Patent number: 10322248
    Abstract: A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 18, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Cagri Giray Besirli, Stephen Smith, Kevin P. Pipe, Gun-Ho Kim
  • Patent number: 10307200
    Abstract: Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: June 4, 2019
    Assignee: Arrinex, Inc.
    Inventor: Vahid Saadat
  • Patent number: 10251693
    Abstract: An ablation assembly includes a handle, a catheter assembly and a connector locking assembly. The catheter assembly includes: a catheter shaft, a balloon and a connector at the distal and proximal ends of the catheter shaft, and a delivery tube extending between there between. The connector includes a connector body secured to the proximal end and a plug secured to the delivery tube, the plug and delivery tube movable axially and rotationally. The handle includes an open portion receiving the plug and the connector body. The connector locking assembly includes: means for simultaneously automatically connecting the plug and the connector body to the handle to place the connector in a load state prior to use, and means for automatically releasing the connector body and thereafter the plug from the handle to place the connector in an eject state to permit the connector to be removed from the handle.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: April 9, 2019
    Assignee: PENTAX OF AMERICA, INC.
    Inventors: Gabriel F. W. Newell, Patrick P. Wu, Timothy Douglas Holland, Cesar A. Ico, Byron Liehwah Chun, Dennis Franklin Burke
  • Patent number: 10251692
    Abstract: A system and method for determining the optimum dose of cryotreatment to an area of target tissue to achieve isolation based on the time to effect (TTE). The system may generally include a treatment device, a sensing device, and a processor programmed to calculate the optimum dose of cryotreatment, in seconds, based on TTE. The TTE may be based on electrical signals received by the processor from the sensing device. The processor may be further programmed to automatically terminate a cryoablation procedure when the optimum dose of cryotreatment has elapsed. The optimum dose of cryotreatment may be the time, in seconds, it takes to achieve isolation, which may be the time it takes for an area of tissue to reach approximately ?20° C.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: April 9, 2019
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10231865
    Abstract: An apparatus for temperature controlling an endocavity such as the rectum during thermal therapy of nearby tissues is disclosed. In some aspects the apparatus is mechanically configured to best conform to the patient. In other aspects the apparatus is designed to eliminate gas bubbles from forming or accumulating in certain volumes that would interfere with the thermal therapy. In other aspects the apparatus is optimized for use in cooling the rectum during ultrasound thermal therapy of the prostate.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: March 19, 2019
    Assignee: Profound Medical Inc.
    Inventors: Owen Moffitt, Michael Wybenga
  • Patent number: 10213244
    Abstract: A cryogenic needle of a cryogenic system is coupled to a heater. While the needle is inserted into target tissue beneath skin, the heater provides heat to protect the skin. Power supplied to the heater is used to interpolate performance of the needle and/or operating parameters of the cryogenic system.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: February 26, 2019
    Assignee: Myoscience, Inc.
    Inventors: Michael Fourkas, Ronald Williams, John Allison, Jesse Rosen