Cyrogenic Application Patents (Class 606/20)
  • Patent number: 11324557
    Abstract: A surgical instrument is disclosed. The surgical instrument includes a shaft, a sensing array and a fluid detection circuit. The sensing array is positioned within the shaft. The fluid detection circuit is electrically coupled to the sensing array, and is configured to determine when a fluid originating from an environment external to the shaft is present within the shaft.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: May 10, 2022
    Assignee: Cilag GmbH International
    Inventors: Frederick E. Shelton, IV, Michael J. Vendely, Jason L. Harris, Gregory J. Bakos
  • Patent number: 11285336
    Abstract: A light-based epilation device having at least two sub-groups of light emission elements, each of the sub-groups of light emission elements having at least one distinct light emission element, wherein the sub-groups of light emission elements are arranged for separate energizing, and a controller unit arranged for energizing the sub-groups of light emission elements in accordance with an energizing sequence so that the light emission unit quasi-continuously emits light
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: March 29, 2022
    Assignee: Braun GMBH
    Inventors: Frank Beerwerth, Uwe Bielfeldt, Dalibor Dadic, Felix Heinemann
  • Patent number: 11229756
    Abstract: A system is disclosed for delivering insufflation gas to a body cavity of a patient during a surgical procedure, which includes an insufflator for delivering a flow of insufflation gas to the body cavity of the patient through a flow path that communicates with a pneumatically sealed trocar, a flow meter for measuring an amount of gas that has been removed from the body cavity by use of a suction device, and a controller operatively connected to the flow meter for receiving a flow measurement from the flow meter to determine when the suction device is in use and an amount of insufflation gas needed to be delivered to the body cavity by the insufflator to compensate for the gas removed from the body cavity by the suction device.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: January 25, 2022
    Assignee: Conmed Corporation
    Inventors: Mikiya Silver, George R. Trutza, Michael J. Kane
  • Patent number: 11213427
    Abstract: A lens/sensor subassembly (318) may include a feedback sensor (324), a data transmission line (302), and an electrical element (328). The feedback sensor (324) may be configured to measure a phenomenon in an eye (100) of a patient during a laser-based ophthalmological therapy. The data transmission line (302) may be configured to communicate feedback data measured by the feedback sensor (324) to a laser-based ophthalmological treatment system (200). The electrical element (328) may be degradable in response to exposure to therapeutic radiation (316). The degradation of the electrical element (328) may interrupt communication of the feedback data measured by the feedback sensor (324) to the laser-based ophthalmological treatment system (200).
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: January 4, 2022
    Assignee: LUTRONIC VISION INC.
    Inventor: Zhen Xiao
  • Patent number: 11160596
    Abstract: Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about ?15° C. to about ?30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: November 2, 2021
    Assignee: Berger Thermal Research Ltd.
    Inventors: Abraham Berger, Avri Hazan
  • Patent number: 11154874
    Abstract: A flow modulation device 300 for controlling a rheological state of a dispensed pressurized fluid includes a porous element 304 and an exit tube. The porous element 304 is in fluid communication with a distal end of an outlet tube 303 and receives pressurized fluid in a first rheological state. The porous element 304 includes a plurality of channels that divide a flow channel into a plurality of flow paths through which the pressurized fluid flows and that modulates the flow of the pressurized fluid. The exit tube 305 includes proximal end 355 and distal end 345 and an intermediate body including a sidewall 365 defining a hollow internal lumen 375. The exit tube 305 is in fluid communication with the porous element 304 and receives the modulated pressurized fluid from the plurality of flow paths and refocuses the fluid to dispense the pressurized fluid in a second rheological state.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: October 26, 2021
    Assignee: CRYOCONCEPTS LP
    Inventors: Lincoln C. Young, Philip Michael Formica, R. Sam Niedbala
  • Patent number: 11116657
    Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: September 14, 2021
    Assignee: ZOLL Circulation, Inc.
    Inventors: Jeremy Thomas Dabrowiak, Jessica Megan Clayton, John Thomas Buckley, Christo Petrov Pamichev, Craig Wendell Pendry, Paul Eric Peterson, Richard Allen Smith, Sean W Yip, John William Jacobsen
  • Patent number: 11033754
    Abstract: A method of delivering light energy to a pathological tissue includes emitting light energy from a first optical element within a cannula, producing a substantially uniform irradiance profile from the light energy within the cannula, transmitting the light energy emitted from the first optical element through a second optical element in thermal contact with a distal end of the cannula to the pathological tissue without ablating the pathological tissue, and conducting thermal energy from the pathological tissue through the second optical element and to the cannula.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: June 15, 2021
    Assignee: LITECURE LLC
    Inventors: Luis De Taboada, Brian Pryor
  • Patent number: 11013527
    Abstract: Systems and methods for treating cellulite including an apparatus that applies or a method involving separating septa to eliminate or reduce the appearance of cellulite. In one approach, an interventional tool is placed between tissue layers to engage and treat septa connecting tissue layers between which fat deposits are contained.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: May 25, 2021
    Assignee: NC8, Inc.
    Inventors: Jonathan Podmore, Earl Bright, II, Joshua Makower, John Hanley, Pablo Acosta, Theodore Ketai, William Sauway Law, Michael Schaller, Bryan Hartley
  • Patent number: 10945780
    Abstract: An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: March 16, 2021
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10888708
    Abstract: A phototherapy device for promoting wound healing and treating pain associated with soft-tissue and musculo-skeletal injuries is presented. The phototherapy device may deliver therapeutic light outputs that are variable, in real time, based in part on morphologic data of the patient measured by the device in real-time.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: January 12, 2021
    Assignee: QC, LLC
    Inventor: Bryan James Stephens
  • Patent number: 10799280
    Abstract: A device, system, and method for identifying an area of ablated tissue. Specifically, the device, system, and method may include a device having one or more fiber sensors and a processing unit for receiving emitted and/or reflected light from tissue and making one or more determinations based on the received light regarding ablated tissue, tissue contact, and/or occlusion. Each of the fiber sensors may include at least one multimode waveguide segment and at least one singlemode waveguide segment, or each of the fiber sensors may be singlemode waveguide. Further, each fiber sensor may have a core with long-period grating for optically coupling light from tissue to the fiber sensor. The processing unit may include a beam processing apparatus and a hyperspectral imaging and analysis apparatus, and may optionally include a light source.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: October 13, 2020
    Assignee: Medtronic CryoCath LP
    Inventor: Rahmani Sara
  • Patent number: 10784074
    Abstract: The invention is directed to a charged particle beam apparatus that enables temperature maintenance in a cooling unit provided inside a vacuum application apparatus using a refrigerant. The charged particle beam apparatus includes a cooling tank that contains a refrigerant for cooling a cooling unit, a cooling pipe that supplies the refrigerant from the cooling tank to the cooling unit, and a unit that leads the refrigerant to liquefy when the refrigerant is biased to a solid.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: September 22, 2020
    Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Takeshi Sunaoshi, Yoshihisa Orai, Haruhiko Hatano, Takashi Mizuo
  • Patent number: 10684047
    Abstract: A system for cryogenic cooling of a remote cooling target comprising a cryogenic cooling device and a flexible cold fluid discharge interface, said flexible cold fluid discharge interface further comprising a flexible outer hose, a flexible middle recirculation line, a flexible inner hose, a flexible cryogen supply line, a first annular vacuum insulating area disposed between said flexible outer hose and said middle recirculation line, and a second annular vacuum insulating area disposed between said flexible inner hose and said flexible supply line. Said outer flexible hose, first evacuated annular segment, recirculation line, inner hose, second evacuated annular segment and supply line are arranged substantially concentrically.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: June 16, 2020
    Inventors: Ajay Khatri, Terence Rufer
  • Patent number: 10582961
    Abstract: The invention relates to a method for cosmetically treating dark spots on the skin, wherein said method is intended for eliminating at least one of said dark spots located in a region of the hand, the face, the limbs or the chest area of a person suffering from such skin hyperpigmentation, characterised in that said method includes a step of applying a spray of cryogenic fluid to said region, which brings the skin temperature to a temperature of between ?4° C. and ?15° C. for a consecutive application period of from 2 to 10 seconds, in order to selectively act on the melanocytes, and to a device for carrying out said method.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: March 10, 2020
    Assignee: Cryobeauty
    Inventors: Denis Marin, Dominique Pacito
  • Patent number: 10433895
    Abstract: A method and system for creating permanent lesions in an area of target tissue, such as tissue at or proximate a junction between a pulmonary vein and the left atrium. The method may generally include positioning a medical device in contact with a pulmonary vein ostium, ablating the tissue, and recording a plurality of temperature measurements from one or more of three temperature sensors. The device may include an occlusion element in communication with a coolant source, a first sensor located distal of the occlusion element, a second sensor located proximal of the occlusion element, and a third sensor located in the occlusion element. One or more temperature measurements may be compared with each other to assess occlusion of the pulmonary vein, and/or may be compared with a set of reference temperatures to predict a real-time temperature within the target tissue.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: October 8, 2019
    Assignee: Medtronic CryoCath LP
    Inventors: Dan Wittenberger, Jean-Pierre Lalonde, Stephen A. Howard
  • Patent number: 10383787
    Abstract: A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: August 20, 2019
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Jesse Nicasio Rosen, Mitchell E. Levinson
  • Patent number: 10293190
    Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: May 21, 2019
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Denise Zarins, Nicolas Zadno, Benjamin J. Clark, Erik Thai, Howard R. Levin, Mark Gelfand
  • Patent number: 10292686
    Abstract: A medical ultrasonic probe includes an ultrasonic probe having a probe head and a connector. The connector includes a fluid cooling system comprising a pump configured to pump a cooling fluid between the connector and the probe head. A damper including a housing has a first portion defining a cavity receiving the cooling fluid and a second portion including a gas that is separated from the first portion by a membrane.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: May 21, 2019
    Assignee: General Electric Company
    Inventors: Erich Birglehner, Thomas Rittenschober
  • Patent number: 10206739
    Abstract: A method and apparatus are disclosed for delivering energy substantially distal to an electrosurgical device. Embodiments of a device of the present invention may comprise an elongate member having one or more electrically insulated portions and a distal face comprising one or more electrically exposed conductive portions for delivering energy substantially distal to the elongate member. At least one of the one or more electrically insulated portions may extend from a proximal region of the elongate member to a distal end of the elongate member. In addition, a method is provided for creating a lesion at a target site within a body of a human or animal using an electrosurgical device.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: February 19, 2019
    Assignee: Avent, Inc.
    Inventors: Neil Godara, Taylor Hillier
  • Patent number: 10085789
    Abstract: A system for alleviating occipital neuralgia. The system has a needle probe having at least one needle. The at least one needle has a proximal end, a distal end, and a needle lumen therebetween, the needle configured for insertion proximate to a location of the occipital nerve. A cooling fluid supply lumen extends distally within the needle lumen to a distal portion of the needle lumen. A cooling fluid source is coupled to the cooling fluid supply lumen to direct cooling fluid flow into the needle lumen. A controller that has at least one processor configured implements an occipital neuralgia treatment algorithm for controlling the cooling fluid source so that liquid from the cooling flow vaporizes within the needle lumen to provide a treatment phase to location of the occipital nerve such that the occipital neuralgia is mitigated.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: October 2, 2018
    Assignee: Myoscience, Inc.
    Inventors: Clint Carnell, John Allison, Jwala Karnik, Jesse Rosen
  • Patent number: 10085787
    Abstract: A cryosurgical probe assembly including a cryosurgical probe having a shaft, an insulation element housed within the cryosurgical probe and being slideably repositionable relative to the shaft, and a fluid supply line having an inlet portion for connection to a cryogenic fluid source.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: October 2, 2018
    Assignee: ENDOCARE, INC.
    Inventors: Thach Duong, Jay J. Eum
  • Patent number: 10070910
    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: September 11, 2018
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Frank W. Ingle, Robert F. Bencini, Josef V. Koblish, Jonathan A. Wohlgemuth, Paul A. Roche
  • Patent number: 10058370
    Abstract: An embodiment of the disclosure includes a method for treating a lung. The method may include inserting a cooling element into an airway of the lung; and damaging tissue disposed radially outward of surface tissue defining the airway via the cooling element.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: August 28, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Christopher J. Danek, Bryan E. Loomas, Thomas M. Keast
  • Patent number: 10058371
    Abstract: A cryotreatment catheter for treating tissue. The catheter may include an outer elongate body, a balloon treatment element coupled to the distal portion of the elongate body with a plurality of balloon lobes radially arranged around the outer elongate body, an inner elongate body rotatably movable within the lumen of the outer elongate body, and a fluid delivery lumen located within the lumen of the outer elongate body and at least partially within the lumen of the inner elongate body. The fluid delivery lumen may be branched at a distal portion into a plurality of linear segments, each linear segment being in fluid communication with one of the plurality of balloon lobes. Each of the balloon lobes may be inflated independently of each other by the linear segments of the fluid delivery lumen.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: August 28, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Rahmani Sara, Lies Safar Remali
  • Patent number: 10028780
    Abstract: Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: July 24, 2018
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10022516
    Abstract: A method is provided for treating a neuromuscular defect in a subject. One step of the method includes locating a target nerve. After locating the target nerve, a treatment probe is provided. The treatment probe includes an elongated body member having a proximal end portion and a distal end portion. The distal end portion includes an energy delivery mechanism for stimulating or ablating the target nerve, a monitoring mechanism, and a fluid aspiration/delivery mechanism. Next, the target nerve is verified as an appropriate target for ablation by stimulating and then monitoring the target nerve via the energy delivery mechanism and the monitoring mechanism, respectively. After verifying the target nerve, a tumescent fluid is injected into the tissue surrounding the target nerve. An electric current is then delivered to the energy delivery mechanism to substantially ablate the target nerve.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: July 17, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventor: Francis A. Papay
  • Patent number: 9999789
    Abstract: The invention relates to a temperature distribution determining apparatus for determining a temperature distribution within an object caused by applying energy to the object. A temperature distribution measuring unit (6, 7) measures a spatially and temporally dependent first temperature distribution in the object (3), while the energy is applied to the object (3) such that the object (3) is heated to a temperature within a first temperature range, and a temperature distribution estimating unit (5) estimates a spatially and temporally dependent second temperature distribution in the object (3) within a second temperature range, which is different to the first temperature range, based on the spatial and temporal dependence of the measured first temperature distribution. Since temperature distributions can be obtained not only in the first temperature range, but also in the second temperature range, the overall temperature range, in which the temperature distribution can be determined, can be increased.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: June 19, 2018
    Assignee: Koninklijke Philips N.V.
    Inventor: Michael Harald Kuhn
  • Patent number: 9980765
    Abstract: The present invention provides methods and apparatus for use in the selective disruption of visceral fat tissue by controlled cooling.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: May 29, 2018
    Assignee: The General Hospital Corporation
    Inventors: Matthew M. Avram, Richard R. Anderson, Joshua Tam
  • Patent number: 9956032
    Abstract: An internally-cooled RF electrode can have a construction that provides for an electrode hub having reduced weight and size.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: May 1, 2018
    Assignee: COSMAN INSTRUMENTS, LLC
    Inventors: Eric R. Cosman, Eric R. Cosman
  • Patent number: 9883900
    Abstract: A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: February 6, 2018
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9883901
    Abstract: Systems, methods, and other embodiments associated with characterizing Radio Frequency Ablation (RFA) lesions using Optical Coherence Tomography (OCT) are described. One example method includes acquiring an OCT signal from a Region Of Interest (ROI) in an ablated material. The example method may also include determining whether a lesion was formed by the ablation by analyzing optical properties of the ROI as recorded in the OCT signal.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: February 6, 2018
    Assignee: Case Western Reserve University
    Inventors: Andrew M. Rollins, Christine P. Fleming
  • Patent number: 9867648
    Abstract: A method and system for automated and semi-automated predictable, consistent, safe, effective, and lumen-specific and patient-specific cryospray treatment of airway tissue in which treatment duration is automatically set by the system following entry of patient information and treatment location information into the system by the user, and treatment spray is automatically stopped by the system when the automatically selected treatment duration has been achieved as determined by the system.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: January 16, 2018
    Assignee: CSA Medical, Inc.
    Inventors: Thomas Mulcahey, Marc Davidson, Brian M. Hanley, Ellen Sheets, Wei Li Fan
  • Patent number: 9849038
    Abstract: Fluid removal systems and methods for removing a fluid from a tissue site are presented. The systems include a semi-permeable inbound conduit, which is fluidly coupled to a treatment-fluid delivery unit, for placement proximate to the tissue site, and a semi-permeable outbound conduit, which is fluidly coupled to the inbound conduit and to a treatment-fluid collector, for placement proximate to the tissue site of a patient. The treatment-fluid collector receives a treatment fluid and a recruited fluid from the tissue site. A recruited-fluid determination unit may be coupled to the treatment-fluid collector to determine a volume of the recruited fluid recruited from the patient. The treatment fluid is any fluid (including a gas) that pulls the fluid from an interstitial and intracellular space. A reduced-pressure treatment subsystem may also be included, among other things, for removing ascites and other fluids from a body cavity.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: December 26, 2017
    Assignee: KCI Licensing, Inc.
    Inventors: George Hutchinson, Richard Paul Mormino
  • Patent number: 9833282
    Abstract: An electrode for an electrosurgical unit is used for ablating and necrosing a living tissue by RF electric energy. The electrode can be a hollow electrode formed in an elongated hollow tube shape, including a non-insulating region of a predetermined length formed on one side, and an insulating region formed on an outer surface other than the non-insulating region. The electrode further can include a saline solution circulation structure that supplies pressurized saline solution for cooling a living tissue which is in contact with the hollow electrode from the outside of the living tissue to the inside of the hollow electrode, and one or more saline solution discharge holes formed in the non-insulating region of the hollow electrode to discharge some of the circulating pressurized saline solution to the living tissue.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: December 5, 2017
    Inventor: Myong-Ki Jun
  • Patent number: 9808304
    Abstract: An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: November 7, 2017
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9724492
    Abstract: A lumen extension member is provided for a catheter having a catheter body and an elongate electrode coupled to the catheter body. The elongate electrode defines an electrode lumen extending therethrough. The lumen extension member is positioned within the electrode lumen and is coupled to the catheter body. The lumen extension member includes a tubular member including a sidewall and at least one opening that extends through the sidewall.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: August 8, 2017
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventors: Alan de la Rama, Cary Hata, William Du, Yongxing Zhang
  • Patent number: 9668671
    Abstract: Navigation and tissue capture systems and methods for navigation to and/or capture of selected tissue using the innate electrical activity of the selected tissue and/or other tissue are described. In the context of left atrial appendage closure, the systems and methods can be used to navigate to the left atrial appendage and capture/control the appendage while a closure instrument (suture, clip, ring) is placed over the appendage and tightened down or a closure method (ablation, cryogenic procedures, stapling, etc.) is performed to close the left atrial appendage. The use of innate electrical activity for navigating devices may be used in connection with other tissues and/or areas of the body.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: June 6, 2017
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, AEGIS MEDICAL INNOVATIONS INC.
    Inventors: Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham, Trevor A. McCaw, Elliot Y. K. Hong
  • Patent number: 9668800
    Abstract: A system for alleviating spasticity of a skeletal muscle having an associated motor nerve. The system may include a needle probe having at least one needle. The at least one needle has a proximal end, a distal end, and a needle lumen therebetween. The needle is configured for insertion proximate to the nerve. A cooling fluid supply lumen can extend distally within the needle lumen to a distal portion of the needle lumen. A cooling fluid source is couplable to the cooling fluid supply lumen to direct cooling fluid flow into the needle lumen. A controller having at least one processor configured to implement a spasticity treatment algorithm for controlling the cooling fluid source so that liquid from the cooling flow vaporizes within the needle lumen to provide a treatment phase to the motor nerve such spasticity of the skeletal muscle is mitigated.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: June 6, 2017
    Assignee: MYOSCIENCE, INC.
    Inventors: Jwala Karnik, Clint Carnell, Jesse Rosen, John Allison
  • Patent number: 9662162
    Abstract: An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: May 30, 2017
    Assignee: AFreeze GmbH
    Inventors: Gerald Fischer, Florian Hintringer
  • Patent number: 9610112
    Abstract: A method in which a location is determined on the skin that is proximate to a sensory nerve that is associated with a painful condition. At least one needle of a cryogenic device is inserted into the location on the skin such that the needle is proximate to the sensory nerve. The device is activated such that the at least one needle creates a cooling zone about the sensory nerve, thereby eliminating or reducing severity of the painful condition.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: April 4, 2017
    Assignee: MYOSCIENCE, INC.
    Inventors: Jwala Karnik, Jason Reynolds, John Allison, Clint Carnell
  • Patent number: 9603650
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: March 28, 2017
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9549772
    Abstract: The present invention relates to devices and methods for altering the tissue in and around an intervertebral disc through localized hypothermia therapy to restore function of the disc and reduce pain. Hypothermia therapy is defined as the reduction of tissue temperature to below that of the equilibrium temperature. Target therapeutic temperatures and times are varied according to the desired treatment effect. Intended effects of hypothermia of the intervertebral disc include cellular disruption leading to cell death and or structural and chemical denaturation within the anulus fibrosus, nucleus pulposus, or nerve fibers, temporary or permanent deadening of the nerves within or surrounding the disc, induction of a healing response, angiogenesis, or accelerated degeneration and/or drying of the nucleus pulposus and/or anulus fibrosus. Various effects can be achieved by reaching different temperatures for differing periods of time or by the proximity of the hypothermia therapy device to the treatment target.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: January 24, 2017
    Inventor: Allen Carl
  • Patent number: 9510888
    Abstract: An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: December 6, 2016
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 9480521
    Abstract: A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: November 1, 2016
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Isaac Kim, Josef V. Koblish, David McGee
  • Patent number: 9439709
    Abstract: A cryoablation system has a catheter that receives working cryogen, the catheter having a catheter body that has a distal section having a freezing element which delivers the working cryogen to a treatment location, and a balloon enclosing the freezing element. The catheter body includes an outer tube that has two delivery tubes and a guide wire tube positioned inside the outer tube.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: September 13, 2016
    Assignee: Cryofocus Medtech (Shanghai) Co., Ltd.
    Inventors: Thach Buu Duong, Min Frank Zeng
  • Patent number: 9408655
    Abstract: A cryoablation apparatus includes a distal energy delivery section to facilitate energy transfer to the tissue, resulting in faster achievement of tissue target temperatures. The energy delivery section includes a first heat exchange region and a second heat exchange region having a different heat exchange efficiency than the first heat exchange region. The first heat exchange region may comprise an increased surface area along a radial portion or length of the cryoprobe in contact with surrounding tissue. The heat exchange region may include ridges, texture, threads, and microtubes which serve to increase the thermal-contacting surface area and provide enhanced cryoenergy to the tissue.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: August 9, 2016
    Assignee: CryoMedix, LLC
    Inventors: Alexei Babkin, Peter Littrup, William Nydam
  • Patent number: 9402676
    Abstract: Cryoablation balloon catheters and methods are described herein. The cryoablation balloon catheter comprises a distal end section and an inflatable balloon member disposed along the distal end section for contacting a target tissue. The balloon member may be inflated with a thermally conductive liquid. One or more cooling microtubes are positioned within the balloon and a single phase liquid coolant is transported from a liquid source, through the microtubes to the distal section, and returned to a reservoir. Cryogenic energy is transferred from the microtubes, through the conductive liquid filling the balloon, through the wall of the balloon, and to the tissue. In a cryoablation balloon catheter, a plurality of flexible microtubes are adhered to a surface of the expandable balloon. Cryoenergy from the microtubes is directly transferred to the tissue.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: August 2, 2016
    Assignee: CryoMedix, LLC
    Inventors: Alexei Babkin, Peter Littrup, Barron Nydam, William Nydam
  • Patent number: 9402675
    Abstract: A tweezers device for the application of cryogenic matter directly on a skin lesion while protecting the collateral skin tissue from being damaged by the cryogenic matter, the device comprising an applicator body configured with opposing tweezer arms, each tweezer arm including a cryogenic matter application element such that when the opposing tweezer arms are closed about the skin lesion, the skin lesion is substantially encased by the cryogenic matter application elements.
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: August 2, 2016
    Assignee: TUVIDERM LLC
    Inventor: Zecharia Lind
  • Patent number: 9400499
    Abstract: Systems and methods for integrating quantum computing systems into mobile systems for the purpose of providing real-time, quantum computer-based control of the mobile systems are described. A mobile system includes a data extraction subsystem that extracts data from an external environment of the mobile system and a quantum computing subsystem that receives data from the data extraction subsystem and performs a quantum computing operation in real-time using the data from the data extraction subsystem. A result of the quantum computing operation influences a behavior of the mobile system, such as the navigation of the mobile system or an action performed by the mobile system. The on-board quantum computing subsystem includes on-board quantum computing infrastructure that is adapted to suit the needs and spatial constraints of the mobile system.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: July 26, 2016
    Assignee: D-WAVE SYSTEMS INC.
    Inventors: Colin P. Williams, Jeremy P. Hilton