Organic Material Containing Patents (Class 606/231)
  • Patent number: 10149923
    Abstract: Implants for osteo and osteochondral repair have been developed. These implants include a series of channels between the upper and lower surfaces of the implants, such that when implanted the lower surfaces are situated in an area rich in bone marrow and the channels provide a means for the bone marrow to migrate through the implant. Preferably the implants are made from resorbable polymer fibers, preferably arranged in braids that are knitted or woven together such that the braids are substantially parallel with each other. The implants may be rolled into a bundle of braids with the axis of the braids substantially parallel to the axis of the bundle, to provide channels along the axis of the bundle. A preferred embodiment includes P4HB fibers braided and knitted into a structure that is coated with a ceramic, preferably physiologic calcium phosphate.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: December 11, 2018
    Assignee: Tepha, Inc.
    Inventor: Andrew J. Carter
  • Patent number: 9549809
    Abstract: An interarticular ligament prosthesis is formed from a plurality of high strength high modulus polymeric fibers. The fibers are independent and free from intrinsic inter-fiber shear coupling found in braided or bonded fibers. The ligament prosthesis is installed with tubular, bone screw anchors. The fibers of the ligament prosthesis pass through the central hole of the anchors and are knotted at one end. The exit holes of the anchors include ceramic eyelets with polished edges. The edges are rounded to a defined radius for desired fatigue life of the prosthesis.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: January 24, 2017
    Assignee: Kyon AG
    Inventors: Slobodan Tepic, Randall Acker
  • Patent number: 9307983
    Abstract: Barbed surgical sutures are prepared with a bioactive agent thereon. In embodiments, the bioactive agent may be an antimicrobial or clotting agent deposited within the angle formed by the barb and the suture body. Placement of the bioactive agent in the angle between the barb and suture body enhances the delivery of the bioactive agent to wound tissue at the point of contact.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: April 12, 2016
    Assignee: Covidien LP
    Inventors: Joshua B. Stopek, Matthew D. Cohen
  • Patent number: 9180229
    Abstract: An antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial metal wherein the anionic polyester has at least one carboxylic acid group. A medical device having an antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial metal wherein the anionic polyester has at least one carboxylic acid group.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: November 10, 2015
    Assignee: Ethicon, Inc.
    Inventors: Modesto Emeta, Robert Di Luccio
  • Patent number: 9138506
    Abstract: The invention relates to a treated HPPE yarn characterized in that the treated HPPE yarn comprises: a porous polyolefin layer that adheres to a surface of a HPPE yarn and covers at least partly the surface of the HPPE yarn; a composition comprising an active agent and which composition is at least partially absorbed within the porous polyolefin layer. The invention further relates to an article comprising the treated HPPE yarn, a device comprising the treated HPPE yarn or the article. The invention also relates to a process for preparing the treated HPPE yarn or treated HPPE yarn structure or treated HPPE yarn configuration and use of the treated HPPE yarn or an article or a device comprising the treated HPPE yarn for automotive applications, marine applications, aerospace applications, medical applications, defense applications, sports/recreational applications, architectural applications, clothing applications, bottling applications, machinery applications.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: September 22, 2015
    Assignee: DSM IP ASSETS B.V.
    Inventors: Gerardus Aben, Edith Elisabeth Van Den Bosch, Claudia Maria Vaz
  • Patent number: 9132032
    Abstract: A method and apparatus for performing eye surgery. A deformable body having shape memory retentive properties is formed with one or more open loops. The body is longitudinally stretched so that it can follow a needle through a small caliber needle track formed in the cornea, into the anterior chamber in front of the iris. There, the body has relaxed and reverted to its original shape. The needle is of such size that the needle track self-closes and no closure stitch is needed. Two sutures are connected to opposite ends of the body and one of the sutures connects the body to the needle. After the body is in the pupil of the iris, the loop openings face the wall of the iris and then the sutures are pulled to displace the body and press it against the wall of the iris to dilate the pupil.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: September 15, 2015
    Inventor: Arnold S. Prywes
  • Patent number: 9080263
    Abstract: The invention relates to a resorbable multifilament comprising a number of individual resorbable filaments of a first type having a first degradation time and a number of individual resorbable filaments of a second type having a second degradation time, wherein the filaments of the first type and the filaments of the second type are arranged in close relationship to form a composite multifilament having a length and a specific composite cross-section comprising cross-sections of the individual filaments of the first type and second type, wherein the cross-sections of the individual filaments of the first and second type are located at determined relative positions, wherein the relative positions amongst the individual cross-sections of the filaments of the first and second types are invariant over the length of the composite multifilament.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: July 14, 2015
    Assignee: NOVUS SCIENTIFIC AB
    Inventor: Per Egnelöv
  • Patent number: 8968363
    Abstract: Methods and devices for retracting tissue in a surgical procedure to allow access to the surgical site. Retractor systems and methods that comprise a retractor frame comprising rotatable arms and a linearly translatable arm, the rotatable arms and the linearly translatable arm each coupled to blades that can angulate. Systems for securing a retractor system to a patient's spine, the systems comprising a retractor blade and a shim device.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: March 3, 2015
    Assignee: Globus Medical, Inc.
    Inventors: Mark Weiman, Jason Cianfrani
  • Publication number: 20150050234
    Abstract: A composite material for the production of a medical device having an antiseptic action includes a matrix of alginate in which the complex of iodopovidone is dispersed. The composite material is used particularly for the production of films, micro-capsules, and suture threads with iodine controlled release.
    Type: Application
    Filed: March 21, 2013
    Publication date: February 19, 2015
    Inventors: Athanasia Athanasiou, Ilker S. Bayer, Ioannis Liakos, Loris Rizzello, Roberto Cingolani, Stefania Sabella, Pier Paolo Pompa
  • Publication number: 20140371767
    Abstract: The present disclosure provides filaments and/or surgical sutures which include an inner core, an outer sheath and a plurality of barbs on a surface thereof. The filaments and/or surgical sutures further include at least one adhesive precursor material which transitions from a non-adherent material to an adhesive material to attach a portion of the filament and/or suture to the surrounding area, such as tissue and/or other portions of the filament.
    Type: Application
    Filed: May 5, 2014
    Publication date: December 18, 2014
    Applicant: Covidien LP
    Inventors: Roland Ostapoff, Timothy Sargeant
  • Publication number: 20140243891
    Abstract: Fixation of soft tissue to bone (or of soft tissue to soft tissue) is performed using a flexible material (for example, a suture strand, a braid, a suture tape, a stuffed suture, or a combination thereof) with a portion having an expanded footprint to provide a cushion or tissue protector between the flexible strand (suture) and the tissue to be attached. The suture and cushion may be manufactured from materials that have properties to amplify the body's healing response. The cushion may have any shape and geometry that provides cushioning action between the suture and the tissue to be fixated. The cushion may be provided along the length of the flexible strand (i.e., the flexible strand may be provided with a cushion) or the flexible strand may extend from the cushion.
    Type: Application
    Filed: February 21, 2014
    Publication date: August 28, 2014
    Applicant: Arthrex, Inc.
    Inventors: Reinhold Schmieding, Dustin T. Libby, Peter J. Dreyfuss, James P. Bradley
  • Publication number: 20140213966
    Abstract: A medical device includes an elongated body including an outer surface having a plurality of barbs extending therefrom and an inner surface defining a lumen therethrough. The elongated body includes at least one channel extending through the inner surface and the outer surface, the channel defined between an inner surface of one of the plurality of barbs and a cut outer surface of the elongated body. A wound treatment material is disposed within the lumen of the elongated body. The barb is configured to move between a first position to close the channel and retain the wound treatment material within the lumen and a second position to open the channel and permit the release of the wound treatment material therethrough.
    Type: Application
    Filed: January 7, 2014
    Publication date: July 31, 2014
    Applicant: Covidien LP
    Inventors: Roland Ostapoff, Timothy Sargeant
  • Patent number: 8703627
    Abstract: An antiadhesive material that is excellent in biocompatibility and bioabsorbability, as well as excellent strength in suturing and bonding, is provided. A reinforcing material 12 made of a biodegradable polymer is placed in a gelatin solution so that the reinforcing material 12 is impregnated with the solution, and the gelatin is caused to gelate and dried. By so doing, an antiadhesive material in which a gelatin film 11 and the reinforcing material 12 are integrated is obtained. The reinforcing material 12 preferably is arranged in a portion of the gelatin film 11 to be subjected to suturing, and preferably is arranged along a periphery of the gelatin film 11. The gelatin film 11 preferably is a cross-linked gelatin film, and the reinforcing material 12 preferably is a nonwoven fabric.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: April 22, 2014
    Assignees: Gunze Limited, JMS Co., Ltd.
    Inventors: Shojiro Matsuda, Yoshimi Tanaka, Yoshito Ikada
  • Publication number: 20140107699
    Abstract: The present disclosure relates to methods for producing, including intra-operatively obtaining, a fixation device, and fixation devices produced thereby, containing an autologous cell concentrate from a physiological solution, wherein the cell concentrate is isolated without the need for centrifugation.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 17, 2014
    Applicant: SMITH & NEPHEW, INC.
    Inventor: Andrew Fraser Thompson
  • Publication number: 20130296933
    Abstract: Ophthalmic suture materials made from biocompatible and biodegradable polymers with high tensile strength for use in drug delivery, methods of making them, and method of using them for ocular surgery and repair have been developed. The suture materials are made from a combination of a biodegradable, biocompatible polymer and a hydrophilic biocompatible polymer. In a preferred embodiment the suture materials are made from a poly(hydroxyl acid) such as poly(l-lactic acid) and a polyalkylene oxide such as poly(ethylene glycol) or a polyalkylene oxide block copolymer. The sutures entrap (e.g., encapsulate) one or more therapeutic, prophylactic or diagnostic agents and provide prolonged release over a period of at least a week, preferably a month.
    Type: Application
    Filed: May 6, 2013
    Publication date: November 7, 2013
    Applicant: The Johns Hopkins University
    Inventors: Fabiana Kimie Kashiwabuchi, Justin Hanes, Hai-Quan Mao, Peter John McDonnell, Himatkumar Patel, Murilo W. Rodrigues, Jesus Vidauri-Martinez, Qingguo Xu, Shuming Zhang
  • Publication number: 20130226234
    Abstract: A self-retaining braided suture comprises a braided suture with tissue retainers formed on the surface such that the suture can engage and retain tissue without knots. The suture includes a plurality of braided fibers which may be covered by a non-braided sheath of a material which enhances the formation, elevation and/or deployment of the retainers. The retainers can be formed so as not to disrupt the braided fibers. The self-retaining braided suture has properties which enhance the tensile strength of the suture while preserving flexibility and durability. Methods for manufacturing and using self-retaining braided suture are also described.
    Type: Application
    Filed: November 16, 2010
    Publication date: August 29, 2013
    Inventors: Rui Avelar, William L. D'Agostino
  • Publication number: 20130226236
    Abstract: The disclosure relates to a suture manufactured using poly octyl cyanoacrylate, and a method for manufacturing same. The disclosure provides a method for manufacturing a suture, and a suture prepared using the method, the method comprising: a step for preparing octyl cyanoacetate by reacting cyanoacetic acid and octane alcohol by 1:1 equivalence ratio under the existence of a solvent; a step for reacting the octyl cyanoacetate and paraformaldehyde by 1:1 equivalence ratio under the existence of a solvent; a step for isolating and refining octyl cyanoacrylate after removing the solvent when the reaction is completed; a step for collecting poly octyl cyanoacrylate from the byproduct left from refining octyl cyanoacrylate; and a step for manufacturing a suture by a braid process after manufacturing a thread by melt spinning and extrusion molding the collected poly octyl cyanoacrylate.
    Type: Application
    Filed: November 2, 2011
    Publication date: August 29, 2013
    Applicant: INTUITIVE MEDI CORP INC.
    Inventor: Dong Jin Kim
  • Publication number: 20130226235
    Abstract: This disclosure relates generally to threads with improved properties comprising cross-linked hyaluronic acid, optimized methods of making such threads and uses thereof, for example, in aesthetic applications (e.g., facial contouring, soft tissue augmentation products), surgery (e.g., sutures), drug delivery, negative pressure wound therapy, moist wound dressing, and the like.
    Type: Application
    Filed: April 10, 2013
    Publication date: August 29, 2013
    Applicant: TauTona Group LP
    Inventor: TauTona Group LP
  • Patent number: 8517935
    Abstract: A surgical retractor includes a plurality of blade assemblies interconnected by a plurality of racks. One or more of the blade assemblies is movable along a rack to selectively expand the retractor. At least one of the blade assemblies includes a blade that is rotatably connected to the blade assembly and that is rotatable independent of other blades of the retractor.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: August 27, 2013
    Assignee: DePuy Synthes Products, LLC
    Inventors: Connie Marchek, William Frasier, Anne Kothari, Sara Dziedzic, Holly Brideau, Thomas J Runco, Nicholas Pavento, Paul Beaudoin
  • Patent number: 8476402
    Abstract: The present invention relates to a novel carbohydrate lactone, functionalized aliphatic polyesters and copolymers formed therefrom, and processes for the preparation thereof from renewable resources.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: July 2, 2013
    Assignee: Imperial Innovations Limited
    Inventors: Charlotte K. Williams, Molly Morag Stevens, Min Tang
  • Publication number: 20130122068
    Abstract: This disclosure relates generally to threads with improved properties comprising cross-linked hyaluronic acid, optimized methods of making such threads and uses thereof, for example, in aesthetic applications (e.g., facial contouring, soft tissue augmentation products), surgery (e.g., sutures), drug delivery, negative pressure wound therapy, moist wound dressing, and the like.
    Type: Application
    Filed: October 10, 2012
    Publication date: May 16, 2013
    Applicant: TauTona Group LP
    Inventor: TauTona Group LP
  • Publication number: 20130072974
    Abstract: The present invention provides that coatings applied to natural, synthetic and recombinant expressed polymer filaments can be used to modify the properties of monofilament and multifilament self-retaining sutures. In an embodiment of the invention, the coating enables the suture to be easily inserted into tissue, whereupon the extended interaction of the coating and the tissue increase the ability of the tissue retainers to hold the suture in the tissue. In an embodiment of the present invention, the coated polymers have a melting point in the range from between approximately 40° C. to approximately 180° C. while retaining tensile strength. In an embodiment of the invention, the increased strength is due in part to the tissue specific reaction generated by the suture coating.
    Type: Application
    Filed: March 7, 2012
    Publication date: March 21, 2013
    Inventor: William L. D'Agostino
  • Publication number: 20130066370
    Abstract: Provided in one embodiment is a suture, comprising: a porous interior component comprising a volume of pores or interstices, the volume comprising a binding surface; and a first number of biological cells dispersed in the volume; wherein the first number of biological cells in the volume is greater than a threshold number representing a second number of the biological cells at 100% confluence on the binding surface.
    Type: Application
    Filed: September 5, 2012
    Publication date: March 14, 2013
    Inventors: Richard H. Spedden, Lew C. Schon, Margaret E. Thorpe
  • Publication number: 20130066369
    Abstract: A suture assembly and a method for making the same is provided. The suture assembly includes a plurality of unbarbed filamentary elements intertwined with one another and at least one barbed filamentary element having a longitudinal axis and having plurality of barbs extending outwardly therefrom in a first direction less than 90 degrees from the longitudinal axis. According to exemplary embodiments, the at least one barbed filamentary may be intertwined along its length with the plurality of unbarbed filamentary elements, and the plurality of barbs extending outwardly beyond the unbarbed filamentary elements, or the primary outer periphery of the at least one barbed filamentary element may be contained within the intertwined unbarbed filamentary elements with the plurality of barbs extending through and outwardly from the plurality of unbarbed filamentary elements.
    Type: Application
    Filed: September 17, 2012
    Publication date: March 14, 2013
    Applicant: Ethicon, Inc.
    Inventors: John P. Collier, David C. Lindh, SR., Jesse G. Nawrocki, Krasimira Hristov
  • Patent number: 8383188
    Abstract: A high strength surgical suture material with improved tie down characteristics and tissue compliance formed of ultrahigh molecular weight polyethylene (UHMWPE) yarns, the suture being coated with arginine-glycine-aspartate (RGD) peptide. The suture has exceptional strength, is ideally suited for most orthopedic procedures, and can be attached to a suture anchor or a curved needle.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: February 26, 2013
    Assignee: University of Connecticut
    Inventors: Augustus D. Mazzocca, Mary Beth McCarthy
  • Publication number: 20130041407
    Abstract: A fluid-swellable fiber in particular for the use as a surgical suture, the fiber comprising chitosan, the fiber's swelling ratio being less than 100%, and a fabric comprising the fiber. Moreover, a method of manufacturing from a chitosan-containing solution a fiber comprising chitosan, wherein during manufacture, the solution is brought into contact with a coagulation medium containing at least one organic solvent, a method of removing a fiber from a living organism, wherein the fiber is at least partly dissolved in a solvent applied from the outside, and a kit comprising a chitosan containing fiber and a solvent for at least partly dissolving the fiber.
    Type: Application
    Filed: February 2, 2010
    Publication date: February 14, 2013
    Applicant: MEDOVENT GMBH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Patent number: 8348974
    Abstract: A spinning solution composition which provides regenerated silk fiber that exhibits a strength and elongation close to those of natural silk fiber, is rapidly degradable in vivo, and can be caused to have ability to gradually release a drug to prevent inflammation; a process for producing such regenerated silk fiber by use of the composition; and regenerated silk fiber obtained through the process.
    Type: Grant
    Filed: March 1, 2007
    Date of Patent: January 8, 2013
    Assignee: National University Corporation Tokyo University of Agriculture and Technology
    Inventor: Tetsuo Asakura
  • Publication number: 20120303057
    Abstract: This invention relates to a suture including a drug-loaded polymer layer and a method of manufacturing the same, and more particularly, to a suture, the surface of which is wound with a film including a drug-loaded biodegradable polymer layer, or coated with a drug-loaded biodegradable polymer layer, and to a method of manufacturing the same.
    Type: Application
    Filed: November 25, 2011
    Publication date: November 29, 2012
    Inventors: Young Bin Choy, Chan Yeong Heo, Ji Eun Lee, Su Bin Park
  • Patent number: 8309222
    Abstract: The present disclosure describes a coating for a surgical filament including a vinyl lactam polymer and a lactone polymer.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: November 13, 2012
    Assignee: Covidien LP
    Inventors: Joshua Stopek, Brian Cuevas, Joseph Hotter
  • Patent number: 8226683
    Abstract: This invention is directed to an absorbable, nitrogenous copolyester composition based on more than 50 percent of ?-caprolactone-derived repeat units, having a number average molecular weight of more than ?30 kDa and its use as (1) an absorbable coating for stents which may also contain a bioactive compound at ?10 percent loading; (2) an absorbable suture or mesh and similar devices; and (3) plugs for blocking the end of seed needles used in radiation therapy.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: July 24, 2012
    Assignee: Poly-Med, Inc.
    Inventor: Shalaby W. Shalaby
  • Patent number: 8216497
    Abstract: Various methods are provided for forming tissue holding devices having predetermined shapes suitable for use in surgical applications, and devices formed in accordance with such methods are also provided. These methods include press forming methods, and press forming methods in combination with profile punching. Tissue holding devices formed in accordance with such methods include various configurations for a core and a plurality of tissue holding elements extending outwardly from the core.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: July 10, 2012
    Assignee: Ethicon, Inc.
    Inventors: David Lindh, Sr., Jesse G. Nawrocki, John P. Collier
  • Publication number: 20120150221
    Abstract: According to an aspect of the present disclosure, a surgical suture needle assembly is provided including an elongate tube defining a lumen through at least a portion of a length thereof; and a wound treatment material contained within the lumen of the suture structure. The present disclosure further provides for methods of using the surgical suture needle assembly in anastomotic procedures and the like.
    Type: Application
    Filed: February 17, 2012
    Publication date: June 14, 2012
    Applicant: Tyco Healthcare Group LP
    Inventor: Frank J. Viola
  • Publication number: 20120121661
    Abstract: Phosphorus-based coatings having a plurality of phosphate moieties, a plurality of phosphonate moieties, or both, covalently bonded to an oxide surface of an implantable substrate exhibiting one or more of the following characteristics: (a) the surface phosphorus-containing group density of the coated regions of the substrate is at least about 0.1 nmol/cm2; (b) the phosphorus-based coating has a thickness of less than about 10 nm; or (c) the surface phosphorus-containing group density of the coated regions of the substrate is equal to or greater than the surface hydroxyl group density of the oxide surface of the substrate. Implantable devices embodying the coated substrates are also disclosed.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 17, 2012
    Applicant: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Jeffrey Schwartz, Ellen S. Gawalt, Michael J. Avaltroni
  • Patent number: 8172873
    Abstract: The present disclosure relates to Shape Memory Polymers (SMP's) comprising function groups that allow the polymers to be elastically deformed, utilized in the elastically deformed state, and subsequently returned to the original polymorphic shape.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: May 8, 2012
    Assignee: University of Rochester
    Inventors: Mitchell L. Anthamatten, Jiahui Li, Christopher L. Lewis
  • Publication number: 20120078297
    Abstract: The present invention relates to a biodegradable suture-type cell delivery system, a preparation method thereof and a biodegradable suture comprising the same. The biodegradable suture-type cell delivery system has improved cell compatibility as a result of depositing a hydrophilic functional group-containing compound on the surface of a biodegradable suture yarn made of a biodegradable polymer, a portion of which has partially a bulky structure beneficial for the proliferation of cells or living tissue, so as to hydrophilically modify the surface, and then bonding a cell compatible material to the surface, and also functions as a cell culture scaffold, because the bulky structure is beneficial for the proliferation of cells. Accordingly, the biodegradable suture-type cell delivery system can improve the rate of engraftment of stem cells in vivo.
    Type: Application
    Filed: November 18, 2009
    Publication date: March 29, 2012
    Applicant: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: Heung Jae Chun, Su Jung You, Ki Dong Yoo, Kyu Nam Park, Gue Tae Chae, Seok Whan Moon, Han Joon Kim, Jung Hee Wee
  • Patent number: 8142475
    Abstract: According to an aspect of the present disclosure, a surgical suture needle assembly is provided including an elongate tube defining a lumen through at least a portion of a length thereof; and a wound treatment material contained within the lumen of the suture structure. The present disclosure further provides for methods of using the surgical suture needle assembly in anastomotic procedures and the like.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: March 27, 2012
    Assignee: Tyco Healthcare Group LP
    Inventor: Frank J. Viola
  • Patent number: 8080593
    Abstract: The present invention relates to thermoresponsive adhesives. The invention further relates to methods for the reversible attachment of retinal implants, other implants, and drug delivery devices.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: December 20, 2011
    Assignee: University of Southern California
    Inventors: Mark Humayun, Buddy R. Ratner, James Weiland, Murat Tunc, Xuanhong Cheng
  • Patent number: 8067368
    Abstract: Vascular endothelial growth factor alternative splice variants and methods of their use are provided.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: November 29, 2011
    Assignees: The Ohio State University Research Foundation, Nationwide Children's Hospital, Inc.
    Inventors: Fredika Robertson, John Bauer
  • Publication number: 20110276090
    Abstract: A medical product including a biocompatible material includes two mutually opposite main surfaces, wherein at least one of the two main surfaces that anchor biological tissues, wherein the barbs protrude from the at least one main surface and are formed by cuts made in the biocompatible material, and wherein the material between the two main surfaces is completely broken through in an area of the cuts.
    Type: Application
    Filed: May 6, 2011
    Publication date: November 10, 2011
    Applicants: ITV Denkendorf Produktservice GmbH, Aesculap AG
    Inventors: Ingo Berndt, Erich Odermatt, Erhard Müller, Sven Oberhoffner
  • Patent number: 8048111
    Abstract: Unique PTFE structures comprising islands of PTFE attached to an underlying expanded polytetrafluoroethylene (ePTFE) structure and to methods of making such structures is disclosed. The ePTFE material may or may not have been exposed to amorphous locking temperatures. These unique structures exhibit islands of PTFE attached to and raised above the expanded PTFE structures.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: November 1, 2011
    Assignee: Gore Enterprise Holdings, Inc.
    Inventors: David Isaac Lutz, Norman Ernest Clough
  • Patent number: 8025676
    Abstract: Provided is a method of producing a bioabsorbable, implantable substrate having a graded molecular weight distribution, comprising exposing at least a portion of the implantable substrate to electron beam irradiation. There is also provided a bioabsorbable, implantable substrate comprising a bioabsorbable polymer having a graded molecular weight distribution through at least a portion of its thickness.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: September 27, 2011
    Assignee: The Queen's University of Belfast
    Inventor: Fraser James Buchanan
  • Publication number: 20110146680
    Abstract: The invention relates to a silicone catheter including chlorhexidine gluconate, methods of making this catheter, and methods of using it. The method of making the catheter includes contacting a silicone catheter with a liquid containing chlorhexidine gluconate. Chlorhexidine gluconate is stably incorporated into the silicone catheter. The invention also relates to a silicone medical device or article including chlorhexidine gluconate and methods of making this such a medical device or article.
    Type: Application
    Filed: June 24, 2010
    Publication date: June 23, 2011
    Inventor: Anthony J. Conway
  • Patent number: 7935131
    Abstract: The present disclosure relates to Shape Memory Polymers (SMP's) comprising function groups that allow the polymers to be elastically deformed, utilized in the elastically deformed state, and subsequently returned to the original polymorphic shape.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: May 3, 2011
    Assignee: University of Rochester
    Inventors: Mitchell L. Anthamatten, Jiahui Li
  • Patent number: 7892256
    Abstract: A suture tape construct is made of braided high strength surgical suture material. A length of round braided suture extends along the entire length of the suture tape. A middle portion of the suture tape features a flat braid added to the round braided suture. The suture is incorporated centrally into the flat braid, providing a backbone to the construct. Transition sections at either end of the flat braid are tapered to allow the suture tape to pass easily through openings during surgical procedures. The suture tape is a braided construction of ultrahigh molecular weight polyethylene fiber blended with fibers of one or more long chain synthetic polymers, preferably polyester. The suture tape is indicated for high demand orthopedic repairs such as arthroscopic reconstruction for acromioclavicular joint separation, for example. The broad footprint of the suture tape is appropriate for repairs in degenerative cuff tissue where tissue pull-through may be a concern.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: February 22, 2011
    Assignee: Arthrex, Inc.
    Inventors: R. Donald Grafton, Stephen S. Burkhart
  • Publication number: 20110022086
    Abstract: The present invention combines synthetic, natural and recombinant polymers for making a self-retaining suture. In an embodiment of the present invention recombinant polyhydroxyalkanoate (rPHA) polymers and/or polyglycolic acid polymers are incorporated into the suture. In various embodiments of the invention, materials are incorporated into the suture to illicit a tissue response reaction. The tissue response reaction results in deposition of collagen around the tissue retainer in the tissue thereby increasing the retention of the tissue retainer in the tissue. In various embodiments of the invention, the core of the suture is made from a material that does not illicit a tissue response reaction. In various embodiments of the invention, the core can be chose to enhance elasticity and strength of the suture.
    Type: Application
    Filed: October 31, 2008
    Publication date: January 27, 2011
    Applicant: ANGIOTECH PHARMACEUTICALS, INC.
    Inventors: William L. D'Agostino, Alexei Goraltchouk
  • Publication number: 20110015673
    Abstract: A surgical suture material with an antimicrobial surface is described, the surface exhibiting a coating containing a) at least one fatty acid, b) octenidine dichloride and/or dequalinium chloride and c) optionally oligomeric lactic acid esters. In addition, a process for coating surgical suture material is described which is characterized by the fact that the thread material is wetted with a homogeneous methanolic solution of octenidine dichloride and/or dequalinium chloride and subsequently the methanol is evaporated, a coating forming on the thread surface.
    Type: Application
    Filed: September 24, 2010
    Publication date: January 20, 2011
    Applicant: HERAEUS KULZER GMBH
    Inventors: Sebastian VOGT, Klaus-Dieter Kühn, Hubert Büchner
  • Patent number: 7850894
    Abstract: Various methods are provided for forming tissue holding devices having predetermined shapes suitable for use in surgical applications, and devices formed in accordance with such methods are also provided. These methods include press forming methods, and press forming methods in combination with profile punching. Tissue holding devices formed in accordance with such methods include various configurations for a core and a plurality of tissue holding elements extending outwardly from the core.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: December 14, 2010
    Assignee: Ethicon, Inc.
    Inventors: David Lindh, Sr., Jesse G. Nawrocki, John P. Collier
  • Publication number: 20100298877
    Abstract: The present invention is directed to recombinant spider silk proteins, nucleic acids, coding for these recombinant spider silk proteins, as well as hosts suitable for expressing those nucleic acids. Furthermore, the present invention is directed to a method of aggregation of spider silk proteins and the use of the proteins in the field of biotechnology and/or medicine and other industrial fields, in particular in the manufacture of automotive parts, in the aircraft construction, in the processing of textiles and leather, as well as in the manufacture and processing of paper and the like.
    Type: Application
    Filed: May 24, 2010
    Publication date: November 25, 2010
    Applicant: AMSILK GMBH
    Inventors: THOMAS SCHEIBEL, DANIEL HUEMMERICH, CHRISTIAN ACKERSCHOTT
  • Publication number: 20100152831
    Abstract: Provided herein are implantable medical devices comprising a biodegradable multiblock copolymer comprising at least three blocks; wherein the at least three blocks includes at least one inner block and two end blocks; further wherein each of the at least one inner block comprises monomers selected from the group consisting of e-caprolactone, r-butylactone, trimethylene carbonate, caprolactone derivatives, P-Dioxanone, and combinations thereof; and further wherein each of the end blocks comprises monomers selected from the group consisting of l-lactide, D-lactide, glycolide, L,D-lactide, and combinations thereof.
    Type: Application
    Filed: December 12, 2008
    Publication date: June 17, 2010
    Applicant: Medtronic Vascular, Inc.
    Inventors: Ya Guo, Kishore Udipi
  • Publication number: 20100113871
    Abstract: The invention relates to a formulation for preparing an antimicrobial lubricious hydrophilic coating, which formulation comprises a hydrophilic polymer; an initiator; particles comprising metallic silver (i.e. Ag°); and a carrier liquid. The invention further relates to an article comprising a hydrophilic coating on a surface wherein the coating comprises a cured hydrophilic polymer and particles comprising metallic silver.
    Type: Application
    Filed: September 13, 2007
    Publication date: May 6, 2010
    Inventors: Aylvin Jorge Angelo Athanasius Dias, Edith Elisabeth M. Van Den Bosch, Astrid Franken