Abstract: The present invention is about an intra-corporal telescopic osteo-distraction device for locking the length of the bone and for providing axial, torsional and bending stability; an extra-corporal force producing device for producing a force for extension causing a lengthening of the intra-corporal device and the bone; a method for bone lengthening and a bone lengthening arrangement utilizing the devices of the invention.

Abstract: Disclosed is an method for use of an intramedullary nail comprising a shaft having a length, a diameter, an exterior bone contacting surface, a leading (or distal) end and a trailing (or proximal) end, wherein the leading end is progressively tapered and comprises a well or cup, adapted to receive the tip of a standard K-wire, the trailing end comprises a driving fitting adapted for attachment to a driving tool for insertion of the nail into the prepared bone, the trailing end may optionally include an internal thread that can be used to secure the nail to a drill guide which can also function as an insertion handle, and the nail's shaft may also optionally be equipped with threaded and/or unthreaded cross-drilled holes for insertion of unicortical locking screws and bone screws, respectively, once the nail is placed as desired.

Abstract: Implants and methods for stabilizing bone fractures are provided. In one embodiment, the implants are spheres. In another embodiment, the implants are rods. The rods can be used to stabilize peripheral portions of a bone fracture. The rods can be shaped and configured to correspond to the shape of a region of bone against which the rod will be deployed. The rods can be provided with surface features for engaging adjacent rods and/or adjacent regions of bone to further stabilize the rods. The spheres can be inserted to fill a remaining volume of the fracture cavity. The implants can be made from orthobiologic materials.

Abstract: A retrograde intramedullary nail for insertion in the medullary canal of a femur includes a body that is elongate and defines a leading end and a trailing end spaced from each other at a length sufficient to extend from an intercondylar region at least to a subtrochanteric region of the femur. The body further defines a leading portion that extends to the leading end. The leading portion defines at least one locking hole configured to receive a fixation member. The at least one locking hole defines a central hole axis that is oriented to extend through the neck and head of the femur.

Abstract: The present invention provides a deformable body (2), wherein the deformable body comprises a force application surface (12) opposite a bone contact surface (52) to be pressed against periosteum of a bone surface (52) of a bone such that the bone contact surface adapts its shape to the shape of the bone surface, wherein the deformable body comprises one or more through-going openings (3) and/or one or more fixation locations (34) arranged to receive a fixation element such as screw (20), and wherein the deformable body comprises an anaesthetic that is released from or through the bone contact surface. The anaesthetic can be bupivicaine, liposome bupivacaine, lidocaine or levobupivacaine. The anaestetic can be arranged in one or more compartments (6, 7) which have different release rates. The screw can comprise a detent or rim to mate with the deformable body. A sleeve (80) can be arranged in the opening (3) to receive the screw.

Abstract: The present invention relates to an implantable bone distraction device (1) for distracting osteotomically separated bone sections (2, 2?), said implantable distraction device (1) comprising a first block (3), a second block (3?), and an actuator (4) including means for adjusting the space between the two blocks, enabling distraction between the first bone section (2) and the second bone section (2?). The implantable bone distraction device (1) further comprises at least one vibration sensor (6) arranged in an area located between the first block (3) and the second block (3?) and oriented in order to measure a vibration response of a medium comprising the implantable bone distraction device (1).

Abstract: The apparatus, systems and methods disclosed herein generally relate to the surgical repair or alteration of bone. More particularly, certain of the disclosed apparatus, systems and methods of the present disclosure relate to the use of a directionally-reinforced composite material to emulate anisotropic structural characteristics of an original anatomic trabecular structure. The directionally-reinforced composite material may generally include a scaffold set in a composite matrix, wherein the scaffold determines the anisotropic structural characteristics of the materials. In some of the embodiments, a scaffold may include at least a first plurality of struts which are generally aligned in a first direction and a second plurality of struts aligned in a second direction.

Abstract: An implant and method for fixation of long bones. The implant provides rotational, longitudinal, and bending stability. The implant comprises one or more elongated members that span the intramedullary cavity of a long bone, a distal tip that expands radially relative to the long axis of the implant, and a locking mechanism at the proximal end of the implant.

Abstract: A system, and method of using the system, for changing the angle of a bone of a subject is provided by the present disclosure.

Abstract: The present invention provides a deformable body (2), wherein the deformable body comprises a force application surface (12) opposite a bone contact surface (52) to be pressed against periosteum of a bone surface (52) of a bone such that the bone contact surface adapts its shape to the shape of the bone surface, wherein the deformable body comprises one or more through-going openings (3) and/or one or more fixation locations (34) arranged to receive a fixation element such as as screw (20), and wherein the deformable body comprises an anaesthetic that is released from or through the bone contact surface. The anaesthetic can be bupivicaine, liposome bupivacaine, lidocaine or levobupivacaine. The anaesthetic can be arranged in one or more compartments (6, 7) which have different release rates. The screw can comprise a detent or rim to mate with the deformable body. A sleeve (80) can be arranged in the opening (3) to receive the screw.

Abstract: A cortical shaft bone fixation apparatus includes a housing having a leading portion and a trailing portion, the leading portion configured to fit within a diameter of an affected cortical shaft bone, the leading portion having first and second sections. The apparatus further includes an expansion mechanism adapted to transition the first and second sections from a first position to a second position, the first and second sections providing an outward force against the inside surface of the cortical shaft bone when the first and second sections transition from the first position to the second position, the trailing portion of the housing abutting a leading end of the affected cortical shaft bone. The trailing portion of the housing includes a pair of angled tapers extending inwardly toward each other to a minimum separation distance at an extreme end of the housing.

Abstract: A tool for manipulating the position of an implantable medical device. In some embodiments the tool includes a readily releasable grasping feature that securely couples the implant to the tool while the implant is being manipulated. Preferably, the user can simply release the implant from the tool. The tool in other embodiments includes an internal pathway for accommodating non-linear implants, such as curved rods, wires, or nails. In yet other embodiments the tool has multiple handles, each handle being adapted and configured to permit manipulation of the implant in a single predetermined orientation, but with alternative handles for grasping in different hand orientations. Still further embodiments pertain to a kit having a tool and a plurality of collets, each collet being adapted and configured to grasp a different size of implant, but each collet having identical tool coupling features such that any collet in the kit can be used with the single tool.

Abstract: An osseous anchoring implant with cortical stabilization. The implant having: an expandable sleeve having a first threading inside and a second threading outside, a screw having an external profile complementary to the internal profile of said expandable sleeve and an external threading with a reverse screw pitch of the second threading, The implant switching from a folded rest position to a deployed position by the actuation of said reversed threading, causing the penetration of the screw into the expandable sleeve and generating the radial expansion of the expandable sleeve by deformation on a distal portion. In the deployed position, the expandable sleeve has a frustoconical shape. The proximal portion of the screw includes an outer osseous anchoring threading and a frustoconical portion whose flaring is reversed relative to that of the expandable sleeve in the deployed position.

Abstract: An osseous anchoring implant with facilitated extraction having: an expandable sleeve extending between a proximal portion, and a distal portion, defining a longitudinal axis, a screw extending between a proximal portion and a distal portion on an axis collinear with the axis, having an external profile complementary to the internal profile of said expandable sleeve, the screw comprising at least one distance marker to visualize the moment when the screwing of the screw in the expandable sleeve must be carried out in the opposite direction to the screwing of the expandable sleeve. The implant switches from a folded rest position to a deployed position by the penetration of the screw in the expandable sleeve. The distal portion including self-tapping notches. The distal portion includes a self-milling head.

Abstract: Joint implants, such as joint implants used for placement in toes to treat hammertoe are described. More particularly, joint implants that include a proximal portion configured to be inserted into a first bone, a distal portion configured to be inserted into a second adjacent bone, and an elongated body positioned between the distal and distal portion is described. The elongated body can define a length and include at least one metal rod extending from the proximal portion to the distal portion and a porous mesh extending along at least a portion of the elongated body length. The porous mesh can be configured to allow for bony in-growth upon implantation, wherein the elongated body defines a generally square cross section and is configured to be inserted into drilled circular holes in the first and second bones. Methods of fusing two adjacent phalanges of a two are also described.

Abstract: The bone fixation tangs with self-balancing extension compensate for the internal cavity shape of the intramedullary canal, thus avoiding the related issues of over-extension and under-extension of tangs. Over-extension, or pushing the tangs too deeply in the inner wall of the bone, is unnecessarily traumatic to the patient and may weaken the bone. Under-extension, or stopping extension before the tangs have locked into the interior surface of the bone, results in reduced mechanical strength, thus compromising the ability of the nail to provide support to the bone. The bone fixation tangs with self-balancing extension address this issue by allowing the tangs to balance their extension.

Abstract: Disclosed is an intramedullary nail comprising a shaft having a length, a constant diameter, an exterior bone contacting surface, a leading (or distal) end and a trailing (or proximal) end, wherein the leading end is progressively tapered and comprises a well or cup, adapted to receive the tip of a standard K-wire, the trailing end comprises a driving fitting adapted for attachment to a driving tool for insertion of the nail into the prepared bone, the trailing end may optionally include an internal thread that can be used to secure the nail to a drill guide which can also function as an insertion handle, and the nail's shaft may also optionally be equipped with threaded and/or unthreaded cross-drilled holes for insertion of unicortical locking screws and bone screws, respectively, once the nail is placed as desired.

Abstract: A composite comprising: a barrier, said barrier being configured to selectively pass water, and said barrier being degradable in the presence of water; a matrix material for disposition within said barrier, wherein said matrix material has a flowable state and a set state, and wherein said matrix material is degradable in the presence of water; and at least one reinforcing element for disposition within said barrier and integration with said matrix material, wherein said at least one reinforcing element is degradable in the presence of water, and further wherein, upon the degradation of said at least one reinforcing element in the presence of water, provides an agent for modulating the degradation rate of said matrix material in the presence of water.

Abstract: An intramedullary bone transport nail configured for axial bone segment transport by an externally applied magnetic field includes a nail body defining an internal chamber; locking portions for locking respective ends of the nail body in first and second bone fragments of a long bone, respectively; and a transport carriage assembly that is arranged in an axially movable manner within the internal chamber of the nail body and has an aperture for accommodating a transport bone segment screw for fixing a middle bone segment of the long bone to the bone transport carriage. The nail body defines an elongated longitudinal opening to allow axial motion of the transport bone segment screw as the transport carriage assembly moves axially by rotation of a threaded rod affixed to a magnetic driver. Rotation of the threaded rod is achieved by application of torque to the magnetic driver by a rotating external magnetic field.

Abstract: An expandable support device for tissue repair is disclosed. The device can be used to repair hard or soft tissue, such as bone. The expandable support device can have interconnected struts. A method of repairing tissue is also disclosed. The expandable support device can be inserted into a damaged bone and radial expanded. The radial expansion of the expandable support device struts can cause the struts to cut mechanically support and/or the bone.

Abstract: A reconfigurable bone adjustment device includes a first member configured for attachment to a first bone fragment, a second member configured for attachment to a second bone fragment, the second member including an elongated slot formed therein; a drive mechanism configured to move the second member relative to the first member; a threaded block fixedly coupled to the first member, the threaded block positioned within the elongated slot; and a threaded rod having a proximal end operatively coupled to the drive mechanism, an intermediate portion threadably coupled to the threaded block, and a distal end operatively coupled to the second member so that rotation of the drive mechanism rotates the threaded rod and moves the second member relative to the first member. The second member being adapted and configured to provide increased strength so that the device can withstand increased patient weight bearing.

Abstract: Intramedullary fixation assemblies (4, 8) and intramedullary fixation devices (1, 24) can be used in orthopaedic surgery for the fixation of bone fractures. Also disclosed is an insertion device (30) for inserting an intramedullary fixation device, and a method of fixing a bone fracture. The fixation devices are preferably for addressing fractures of the distal radius, and are preferably styloid nails. The styloid nails preferably have a head portion that can accept up to three bone screws; one of the bone screws is designed to extend across a fracture line between a proximal and a distal bone fragment while the other bone screws are designed to be retained in the distal bone fragment.

Abstract: An implantable growing rod assembly adapted to be secured along a length of a spine for treating deformities of the spine. The assembly includes a housing, a fixed rod extending along a longitudinal axis away from the housing, and an expansion rod extendible from the housing along the longitudinal axis. A driver assembly is fixed to the housing and adapted to translate the expansion rod along the longitudinal axis.

Abstract: Arthrodesis devices and arthrodesis procedures are disclosed herein. In an embodiment, an arthrodesis device includes a shape memory material connecting member attached to two points of fixation.

Abstract: The invention relates to a self-expanding intraosseous stent (100) intended to contain intraosseous cement, characterized in that the stent comprises a central part (101) and two lateral parts (102, 103) arranged on either side of the central part and extending along the same longitudinal axis (X), and in that the central part has a radial force lower than the radial force of the lateral parts.

Abstract: Described herein is an apparatus for guiding an elongated flexible instrument, the apparatus comprising a telescoping support assembly including a plurality of support members extending along a longitudinal axis between a proximal end and a distal end. Each of the support members comprises a ring having an inner surface, an outer surface, and at least one flange. Each flange extends from the inner surface of the ring to define a central passageway extending along the longitudinal axis and having a substantially constant width, which is configured to receive the elongated flexible instrument. The assembly is configured to selectively transition from a compressed to an expanded configuration along the longitudinal axis while each support member is interlocked with at least one other support member, and is adapted to support the elongated flexible instrument as the instrument is advanced along the longitudinal axis.

Abstract: Intramedullary systems, expandable intramedullary nails, expandable anchors, and methods of using the same. The intramedullary system may include an expandable intramedullary nail configured to extend into an intramedullary canal of a long bone and/or one or more expandable anchors configured to extend at an angle transverse to the intramedullary nail. The intramedullary nails and/or anchors may include one or more integrated expansion mechanisms that allow for insertion in a contracted configuration and expansion into a deployed configuration to lock the relative position and prevent axial rotation and translation of the system.

Abstract: An implant and method for fixation of long bones. The implant provides rotational, longitudinal, and bending stability. The implant comprises one or more elongated members that span the intramedullary cavity of a long bone, a distal tip that expands radially relative to the long axis of the implant, and a locking mechanism at the proximal end of the implant.

Abstract: A bone adjustment device such as, for example, an intramedullary lengthening nail may include a first or outer body portion having a notch, a second or inner body portion, a threaded shaft coupled to the first body portion to rotate relative thereto, an inner magnet received by the first body portion and coupled to the threaded shaft for rotation therewith, and a threaded block positioned in the notch, the threaded block having internal threads, the threaded shaft passing through the threaded block and threadedly engaging with the internal threads. Various reconfiguration assembly embodiments include welding the threaded block to the first body portion, the notch being located a distance from the distal end of the first body portion, an overlapping arrangement between the first body portion and the second body portion, and a collar positioned over the first body portion.

Abstract: A system including an intramedullary nail and an insert dimensioned to be positioned within the intramedullary nail. The insert can include a rotating component configured to rotate about a rotational axis transverse to a longitudinal axis of the intramedullary nail. The insert can be configured to receive a bone screw, rotate about the rotational axis as the bone screw is positioned at a selected angle of a plurality of angles relative to the intramedullary nail, and lock the bone screw at the selected angle.

Abstract: An orthopedic implant for insertion into a bone includes an implant body and one or more magnetically activated self-tapping screws. The one or more magnetically activated self-tapping screws are prepositioned in the implant body transversally to a longitudinal axis of the implant body. The prepositioned self-tapping screws are configured to rotate under an influence of an externally applied magnetic field so as to protrude into the bone and lock the orthopedic implant in place.

Abstract: Apparatus and methods for bone fracture repair. The apparatus may include a structural support for positioning a first bone segment relative to a second bone segment. The apparatus may include an anchoring substrate. The anchoring substrate may be configured to compress the first bone segment to the second bone segment. The anchoring substrate may transmit tension from a distal bone segment anchor in the first bone segment to a proximal bone segment anchor in the second bone segment. The apparatus may be configured to be deployed percutaneously in an inner cavity of a bone. The apparatus may be installed in an open fracture. The apparatus may be expanded, self-expanding or configured for mechanically actuation. Some embodiments of the apparatus may include a central axis member that may be used in conjunction with expansion of one or both of the structural support and the anchoring substrate to configure the apparatus.

Abstract: Intramedullary fixation device, having an intramedullary rod (2) which is provided for insertion thereof into a bone (1) and consists of a central screw (4) having a first free end comprising a stopper (7) and a second free end with a pre-tensioning nut (8), an alternating series of expanders (3) and bolts (5) being arranged in between, the bolt surfaces in contact with the expanders (3) having a wedge shape. The bolts (5) or expanders (3) may have no, or one or more variations in the dimensions of the different geometric parameters, in accordance with the adjacent expanders, along the length of the implant, and the central screw (4) may have a variable cross section. The device may have different additional components, such as an osteotomic base (9) for fixation of the musculature. The device promotes maximum nailing limited between these elements and produces a controlled peripheral radial deformation.

Abstract: The present application relates to repair systems, and more particularly to fifth metatarsal repair systems and methods of use. The repair systems described herein can include a fixation device with a threaded section. The repair systems described herein can include one or more grippers designed to be deflected outward to grip the sidewalls of an intramedullary canal of the fifth metatarsal. The repair systems described herein can include an end cap. The end cap can include a fastener including thread designed to engage the threaded section of the fixation device. The end cap can include a cap designed to move relative to the fastener.

Abstract: A spinal correction apparatus comprises a body. A ratchet is disposed with the body. A longitudinal element is connected to the ratchet. A force is applied to at least a portion of the apparatus that causes dynamic incremental movement of the longitudinal element relative to the body in at least one direction. Methods of use are disclosed.

Abstract: An intramedullary nail for surgical use with pediatric patients aged 18 months and older who are diagnosed with Osteogenesis Imperfecta. The intramedullary nail is used to correct deformity, stabilize fractures, and to prevent fractures. The intramedullary nail includes male components that can be nested with a straight formed female component. The angled female component has a telescopic structure that grows together with the child's bone without hindering growth. The intramedullary nail also includes at least one telescopic nail with a corkscrew tip that provides minimal damage.

Abstract: A fastening device having a bellows-like or accordion-like structure made of a material that changes shape when activated by a catalyst, and having pleated or foldable zigzag elements that contract from an extended state to a contracted state upon activation. These elements are formed from zig and zag segments of various shapes. The shape changing material may be a shape memory metal alloy, shape memory polymer or elastic memory composite. A method of using this fastener provides apposition and compression of abutment surfaces to join together two pieces of material, and is suitable for joining apposing bone surfaces together to heal fractures via the use of orthopedic hardware.

Abstract: The invention relates to a resorptive intramedullary implant between two bones or two bone fragments. The implant includes a single-piece body (1) having a generally elongate shape and having, at each end, areas for anchoring to the bone portions in question, characterized in that one of said areas (A1) has a cylindrical cross-section while the other area (A2) has a flat cross-section.

Abstract: A drill guide assembly for drilling a tunnel having a fixed, non-zero radius of curvature, where the drill guide assembly includes a housing and a sleeve, or cutting tube, configured to reciprocate within the distal portion where the sleeve, or cutting tube, is configured to receive a bone cutting instrument.

Abstract: A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substrate for engineering periosteal grafts.

Abstract: An intramedullary nail for fixation and stabilization of a fractured bone that also allows for a controlled amount of longitudinal motion at the fracture site to encourage bone remodeling and healing is described. The intramedullary nail has a proximal portion and a distal portion that are coupled together in a manner by a biasing assembly that provides for a controlled movement of the proximal and distal portions relative to each other so that when a patient puts pressure on the bone, such as when walking, the fracture site compresses and the bone ends move together, and when the pressure is released from the bone, the bone ends are biased apart by a controlled amount.

Abstract: The present invention relates generally to a pharmaceutical formulation for use in the treatment and/or prevention of restenosis in a subject in need thereof. Methods of treatment and/or prevention are also provided.

Abstract: Arthrodesis devices and arthrodesis procedures are disclosed herein. In an embodiment, an arthrodesis device includes a shape memory material connecting member attached to two points of fixation.

Abstract: A system for moving a portion of a patient's body including a housing having a first cavity extending along a longitudinal axis, a first distraction rod having a proximal end and a distal end, the first distraction rod and the housing being telescopically displaceable with respect to each other along the longitudinal axis, the first distraction rod having a cavity extending along the longitudinal axis, a second distraction rod having a proximal end and a distal end and configured to be telescopically displaceable from within the second cavity along the longitudinal axis, and a drive system configured to move the first distraction rod in relation to the housing and to move the second distraction rod in relation to the first distraction rod.

Abstract: Two implant devices cooperate to form a single reinforcement device for minimizing the risk of future hip fractures in the vulnerable intertrochanteric and adjacent femoral neck regions of a patient identified as being at significant risk for hip fracture.

Abstract: The implant fixation systems disclosed herein include an implant manufactured with, or coupled to, one or more implant fixation devices used to secure the implant to bone. Various implant fixation device embodiments have an engagement element with a concave engagement tip, a guiding element defining a planned trajectory along which the engagement element is configured to move, and an adjustment element configured to move the engagement element along the planned trajectory. Moving the engagement element along the planned trajectory causes the concave engagement tip to enter a bone in a first position and rotate within the bone to a second position. Continuing to move the engagement element along the planned trajectory may cause the concave engagement tip to undergo translational movement from the second position to a third position, thereby pulling the implant towards the bone and exerting compression forces on the bone.

Abstract: An intramedullary device to repair a bone in a mammalian body and comprising an elongate nail having a stem and a head. The head is provided with a transverse aperture adapted to receive a fastener. An adjustment mechanism is carried by the head for pivoting the fastener from a first angled position relative to the head to a second angled position relative to the head. A set screw is carried by the head. The distal end of the set screw is movable relative to the proximal end of the set screw from a first position for lockably engaging the fastener in the first angled position and a second position for lockably engaging the fastener in the second angled position. A sealing cap and an apparatus having a cap and a set screw are additionally provided.

Abstract: The invention relates to an apparatus for displacing tissue within the body, wherein the apparatus includes two or more attachment members selectively displaceable with respect to each other via a driving member. The driving member preferably is rotatable and is caused to rotate by a magnetic actuator that can be activated by a magnetic field from outside the body.

Abstract: The present invention is generally directed to intramedullary nails that can include a keel configured for rotational stabilization and/or a multi-sectioned rod configured to apply compression to a fracture.

Abstract: A bone transport system includes a nail having a proximal end and a distal end, the proximal end configured for securing to a first portion of bone, the distal end configured for securing to a second portion of bone. The system includes a housing having a wall with a longitudinal opening extending a length along a portion thereof. The system further includes a transport sled having a length that is shorter than the length of the longitudinal opening, the transport sled configured for securing to a third portion of bone, the transport sled further configured to be moveable along the longitudinal opening. The system further includes a magnetic assembly disposed within the nail and configured to be non-invasively actuated by a moving magnetic field, wherein actuation of the magnetic assembly moves the transport sled along the longitudinal opening. The system further includes a ribbon extending on opposing sides of the transport sled and substantially covering the longitudinal opening.