Angioplasty Patents (Class 606/7)
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Patent number: 11559673Abstract: A dilation catheter includes a shaft, a distal tip sized and configured to pass through an isthmus of a Eustachian tube (ET), and an expandable element moveable along an exterior of the shaft between a proximal position and a distal position. The expandable element is operable to transition between an unexpanded state in which the expandable element is configured for insertion into the ET via the isthmus, and an expanded state in which the expandable element is configured to dilate the ET.Type: GrantFiled: May 3, 2019Date of Patent: January 24, 2023Assignee: Acclarent, Inc.Inventors: Jetmir Palushi, Fatemeh Akbarian
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Patent number: 11541214Abstract: A balloon dilation catheter includes a substantially rigid inner guide member and a movable shaft coupled to a balloon that is slidably mounted on the substantially rigid inner guide member. To treat a sinus cavity of a subject using the balloon dilation the substantially rigid inner guide member is advanced into a drainage pathway of the sinus (e.g., frontal recess) of the subject via a nasal passageway. The shaft and balloon are advanced in a distal direction over the substantially rigid inner guide member to place the balloon in the drainage pathway. The balloon is inflated to expand or otherwise remodel the drainage pathway.Type: GrantFiled: June 18, 2019Date of Patent: January 3, 2023Assignee: Entellus Medical, Inc.Inventors: John R. Drontle, Anthony J. Hanson
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Patent number: 11525954Abstract: The present invention relates to a glass fiber (1) comprising at least one fiber core (10), at least one fiber cladding (11) which at least substantially encloses the fiber core (10) in the circumferential direction (U) and along the longitudinal axis (X), and at least one fiber coating (12) which substantially encloses the fiber cladding (11) in the circumferential direction (U) and along the longitudinal axis (X), wherein the glass fiber (1) has at least one first exposed portion (13a) where the fiber cladding (11) is exposed by the fiber coating (12), for removing light (B) at least from the fiber cladding (11), wherein at least the fiber cladding (11) has a plurality of recesses (14) at least substantially in the radial direction (R), which recesses are designed to at least partially discharge the light (B) at least from the fiber cladding (11).Type: GrantFiled: May 19, 2021Date of Patent: December 13, 2022Inventor: Thomas Theeg
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Patent number: 11484366Abstract: An apparatus includes a proximal portion and a distal portion attached to the proximal portion. The proximal portion includes a proximal surface. The proximal portion defines a first pathway and a second pathway that both extend distally from the proximal surface. The first pathway is dimensioned to receive a shaft while the second pathway is dimensioned to receive a navigation guidewire. The distal portion includes a distal tip terminating into a distal end. The second pathway extends from the proximal portion into the distal tip.Type: GrantFiled: September 27, 2019Date of Patent: November 1, 2022Assignee: Acclarent, Inc.Inventors: Azhang Hamlekhan, Jetmir Palushi, John H. Thinnes, Jr., Krishna Murthy Rajan, George L. Matlock
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Patent number: 11446089Abstract: Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This “minimal contact persistent dilation system” prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.Type: GrantFiled: October 22, 2021Date of Patent: September 20, 2022Assignee: Photothrombotics, Inc.Inventors: Brant D. Watson, Henry W Van Vurst, IV
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Patent number: 11369273Abstract: Provided is a guidewire connector that does not interfere with an introduction of another in-body insertion instrument and is capable of maintaining cleanliness of the guidewire when connecting a guidewire mounted with a photo-acoustic ultrasonic wave generator. The guidewire connector according to the present disclosure includes an adapter member detachably attached to an light emitting apparatus, and a wire fixing member attaching the guidewire to the adapter member, in which the wire fixing member has an outer diameter equal to or smaller than an outer diameter of the guidewire.Type: GrantFiled: May 26, 2020Date of Patent: June 28, 2022Assignee: FUJIFILM Healthcare CorporationInventors: Ryo Imai, Tomohiko Tanaka
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Patent number: 11147875Abstract: Provided herein are conjugates, compositions and methods for use in photoimmunotherapy, such as photoimmunotherapy induced by activation of a phthalocyanine dye conjugated to a targeting molecule that binds a protein on cell, for example, an IR700-antibody conjugate. In some embodiments, the phthalocyanine-dye conjugate can be activated by irradiation with near-infrared light. Features of the conjugates, compositions and methods, including the dose of the conjugate, provide various advantages, such as lower toxicity and/or improved efficacy. In some embodiments, also provided is a dual label phthalocyanine-dye conjugate in which the targeting molecule is conjugated to an additional fluorescent dye, which can be used for photoimmunotherapy while, for example, also exhibiting improved performance for imaging or detection. Also provided are therapeutic methods using the conjugates and compositions for treatment of diseases and conditions, including tumors or cancers.Type: GrantFiled: May 23, 2019Date of Patent: October 19, 2021Assignee: Rakuten Medical, Inc.Inventors: Merrill Biel, Roger Heim, Miguel Garcia-Guzman
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Patent number: 11129676Abstract: An endoluminal lasing system for treating vascular disorders is disclosed. Treatment comprises an elongated member that conveys laser radiation to tissue and a motorized mechanism, through which elongated member is rotated. As motor drives, its movement spins elongated member leading to a spiral movement as physician manually moves member in a longitudinal direction. In a preferred embodiment, elongated member is an optical fiber for endoluminal vessel treatment. In another preferred embodiment optical fiber comprises an off-axis firing distal end or side-firing distal end. Optical fiber can be a radial emitting fiber. Spin velocity can be varied according to treatment needs, i.e., pathology, type of vessel, energy source, vessel diameter, etc. One advantage, spiral movement prevents adherence to vessel wall in treatments. Another advantage is that radiation is applied more uniformly along vessel wall. The vessel wall is, thus more evenly treated under most conditions.Type: GrantFiled: January 20, 2011Date of Patent: September 28, 2021Assignee: Biolitec Unternehmensbeteiligungs II AGInventor: Wolfgang Neuberger
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Patent number: 11090117Abstract: Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.Type: GrantFiled: December 16, 2020Date of Patent: August 17, 2021Inventors: Yoel Zabar, Oren Meshulam Stern, Ilan Ben Oren
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Patent number: 11064935Abstract: A test device is used to test photosensitivity of a skin. The test device is provided with an irradiation unit including a plurality of light irradiation units arranged in a first direction. The plurality of light irradiation units output, in a second direction intersecting the first direction, irradiation light beams that mutually differ at least in one of wavelength characteristics and intensity. The irradiation unit is configured such that intensities of the irradiation light beams output from the plurality of light irradiation units are progressively smaller in the first direction.Type: GrantFiled: March 13, 2018Date of Patent: July 20, 2021Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, NIKKISO CO., LTDInventors: Michihiro Kono, Masashi Akiyama, Yasushi Ogawa, Hideki Asano, Suguru Mishina, Satoru Matsuzawa
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Patent number: 10722293Abstract: A medical instrument includes a housing and a shaft coupled to the housing. The shaft has a proximal end and a distal end. An end effector assembly is disposed at the distal end of the shaft. The end effector assembly includes first and second jaw members. At least one of the first and second jaw members is movable from a first position wherein the first and second jaw members are disposed in spaced relation relative to one another to at least a second position closer to one another wherein the first and second jaw members cooperate to grasp tissue therebetween. The medical instrument also includes one or more light-emitting elements and one or more light-detecting elements configured to generate one or more signals indicative of tissue reflectance. The one or more light-emitting elements are adapted to deliver light energy to tissue grasped between the first and second jaw members.Type: GrantFiled: May 25, 2016Date of Patent: July 28, 2020Assignee: COVIDIEN LPInventors: Shobhit Arya, Neil T. Clancy, Daniel S. Elson, George B. Hanna, Danail V. Stoyanov, Xiaofei Du
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Patent number: 10653482Abstract: A method for photoselective vaporization of prostate tissue includes delivering laser radiation to the treatment area on the tissue, via an optical fiber for example, wherein the laser radiation has a wavelength and irradiance in the treatment area on the surface of the tissue sufficient because vaporization of a substantially greater volume of tissue than a volume of residual coagulated tissue caused by the laser radiation. The laser radiation is generated using a neodymium doped solid-state laser, including optics producing a second or higher harmonic output with greater than 60 watts average output power. The delivered laser radiation has a wavelength for example in a range of about 200 nm to about 650 nm, and has an average irradiance in the treatment area greater than about 10 kilowatts/cm2, in a spot size of at least 0.05 mm2.Type: GrantFiled: January 16, 2014Date of Patent: May 19, 2020Assignee: Boston Scientific Scimed, Inc.Inventors: Scott A. Davenport, Steven G. Murray, Tony D. Coleman, Henry Garlich, Kenneth J. Arnold, Kester Nahen
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Patent number: 10537387Abstract: The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking occurs through use of ultrasound energy. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves by means of shielding it from the effects of laser radiation.Type: GrantFiled: April 16, 2015Date of Patent: January 21, 2020Assignee: DIGMA MEDICAL LTD.Inventors: Ilan Ben Oren, Irit Yaniv, Tamir Wolf, Avia Herschkovitz
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Patent number: 10441156Abstract: A surgical instrument includes an optical fiber having a proximal end and a distal end, the optical fiber configured to emit light at the distal end. The surgical instrument also includes at least one scattering material coupled to the proximal end, the distal end, or a combination of both the proximal end and the distal end.Type: GrantFiled: September 9, 2015Date of Patent: October 15, 2019Assignee: Medical Instrument Development Laboratories, Inc.Inventor: Erik William Peterson
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Patent number: 10342594Abstract: A balloon catheter (10) has a shaft (12) having an elastically expandable balloon (11) on the distal end side and space provided inside and allowing a fluid to flow into and flow out the balloon (11), a heat generating member (22) provided in the internal space of the balloon (11), and optical fibers (20A, 20B) which are extended up to the internal space of the balloon (11) along the shaft (12) and emit light beams input into the proximal end to the heat generating member (22) from the distal end.Type: GrantFiled: July 1, 2015Date of Patent: July 9, 2019Assignee: Nipro CorporationInventors: Katsuya Miyagawa, Yuuki Nishimura, Natsumi Shimazaki
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Patent number: 10182708Abstract: A system in one embodiment includes an image forming device for forming an image from an area of interest containing different image components; an illumination device for illuminating the area of interest with light containing multiple components; at least one light source coupled to the illumination device, the at least one light source providing light to the illumination device containing different components, each component having distinct spectral characteristics and relative intensity; an image analyzer coupled to the image forming device, the image analyzer decomposing the image formed by the image forming device into multiple component parts based on type of imaging; and multiple image capture devices, each image capture device receiving one of the component parts of the image. Additional systems and methods are presented.Type: GrantFiled: August 31, 2012Date of Patent: January 22, 2019Assignee: Lawrence Livermore National Security, LLCInventor: Stavros G. Demos
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Patent number: 9814899Abstract: Systems and methods for illumination of a vascular space and its contents using an electromagnetic energy source that supplies a plurality of wavelengths ranging from ultraviolet to infrared are shown. Illumination can be performed using multiple wavelengths, simultaneously or sequentially, and can be performed in accordance with a protocol where an initial illumination produces an effect that is at least partially reversed by a subsequent illumination. Illumination protocols can be stored on a database and accessed via a user interface displayed on the electromagnetic energy source. The database can be used to store data related to performance of system components, and such data can be used to override or modify an illumination protocol.Type: GrantFiled: July 3, 2014Date of Patent: November 14, 2017Assignee: UVLrx Therapeutics, Inc.Inventors: Scot Johnson, Michael Harter
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Patent number: 9510900Abstract: An electrosurgical device and methods are disclosed for creating a channel through a region of tissue. The device comprises an elongate member for receiving the energy from an electrical energy source. An electrical insulation layer surrounds the elongate member along the device proximal region. An electrode tip is coupled to the distal end of the elongate member for delivering the energy, the electrode tip being configured and sized for delivering the energy in a manner such that electrical arcing is generated in the region of tissue in order to create a channel through at least a portion of the region of tissue. An electrically insulative thermal shield is disposed between the electrode tip and the device proximal region for preventing arcing therebetween during the delivery of the energy and for thermally protecting the device proximal region from heat produced by the delivery of the energy through the electrode tip.Type: GrantFiled: November 8, 2010Date of Patent: December 6, 2016Assignee: BAYLIS MEDICAL COMPANY INC.Inventors: Rund Abou-Marie, Taras Juzkiw, Gareth Davies, Maria Luk, Ramsey Leung, Mark Mosley, Christine Wong, Kelly Albert
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Patent number: 9456871Abstract: An optical fiber includes an internal fiber, an end surface, a first cap member and a second cap member. The internal fiber terminates at a fiber tip. The end surface transmits laser energy delivered through the internal fiber. The first cap member extends over the end surface and includes a first end on a first side of the end surface and a second end on a second side of the end surface. The second cap member extends over the first cap member and includes a first end on the first side of the end surface and a second end on the second side of the end surface, the second end of the second cap member is attached to the second end of the first cap member.Type: GrantFiled: August 28, 2014Date of Patent: October 4, 2016Assignee: Boston Scientific Scimed, Inc.Inventors: Yihlih Peng, Gerald M. Mitchell
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Patent number: 9375328Abstract: An angioplasty balloon including a non-deployable stent to prevent or reduce the potential for slippage of the inflated balloon with respect to the vessel wall being treated. The balloon includes a non-deployable stent that is adapted to be secured to the balloon or angioplasty balloon catheter. The stent has a proximal end, a distal end, and at least three radially-spaced struts, each, each strut connecting the proximal end to the distal end and having one or more bends that allow expansion of the strut to accommodate the inflation of the balloon. The stent is made or a material so that the stent collapses upon deflation of the balloon.Type: GrantFiled: January 26, 2010Date of Patent: June 28, 2016Assignee: AngioScore, Inc.Inventor: Robert C. Farnan
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Patent number: 9314303Abstract: A handheld controller for laser surgical applications includes a variable time delay control to allow a surgeon to delay interruption of laser firing in response to feedback from an overheating detector, and a detector sensitivity control for changing a sensitivity of the detector.Type: GrantFiled: March 23, 2011Date of Patent: April 19, 2016Inventor: Joe Denton Brown
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Patent number: 9308047Abstract: Embodiments of a balloon biasing laser catheter are provided. In some embodiments, the laser catheter may include a distal tip that extends from the distal end of the catheter from a point near the light guide aperture. The distal tip may be disposed at the periphery of the catheter. In some embodiments, a balloon may be disposed between the light guide aperture and the distal tip, such that the a light guide extending from the aperture may be disposed proximate with the distal tip having the balloon in between. A retaining wire may be coupled with the distal tip and slidably coupled with the light guide. The retaining wire may keep the light guide biased relatively parallel with the distal tip and/or the catheter body when the balloon is inflated. The light guide may include a guidewire lumen the extends to the distal end of the distal tip.Type: GrantFiled: December 20, 2013Date of Patent: April 12, 2016Assignee: The Spectranetics CorporationInventors: Kevin D. Taylor, Wade Bowe
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Patent number: 9254175Abstract: Expandable laser catheters for utilizing laser energy to remove obstructions from body passages are described. In one embodiment, the laser catheter includes a shaftway having a distal end including a flexible portion configured in a series of radial folds. Multiple optical fibers, configured to transmit laser energy, extend along the shaftway and are attached to the flexible portion. An inflatable, ring-shaped balloon is attached to the catheter within the flexible portion. In use, the catheter is inserted into a body passage such as an artery, and advanced until the distal end is adjacent to an obstruction. The balloon is inflated to expand the flexible portion and to bring the optical fibers nearer the inner wall of the body passage. Laser energy is directed by the optical fibers toward targeted regions of the obstruction. As the catheter is advanced and the process repeated, a core is formed from the obstruction and contained within the flexible portion.Type: GrantFiled: May 20, 2013Date of Patent: February 9, 2016Assignee: The Spectranetics CorporationInventors: Thomas R. Winston, John M. Neet
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Patent number: 9237966Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.Type: GrantFiled: April 24, 2015Date of Patent: January 19, 2016Assignee: Katalyst Surgical, LLCInventors: Gregg D Scheller, Craig Moore, Matthew N Zeid
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Patent number: 9220917Abstract: Apparatus, devices, methods, systems, computer programs and computing devices related to autofluorescent imaging and ablation are disclosed.Type: GrantFiled: August 24, 2007Date of Patent: December 29, 2015Assignee: The Invention Science Fund I, LLCInventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Eric C. Leuthardt, Nathan P. Myhrvold, Dennis J. Rivet, Thomas Allan Weaver, Lowell L. Wood, Jr.
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Patent number: 9198726Abstract: A method and system for ablation of cardiac tissue in a living being via the esophagus is provided. The method includes the step of introducing a photodynamic substance to the cardiac tissue. A deformable, elongated body defining a proximal end and a distal end is inserted into an esophagus of the living being. The distal end of the elongated body is located proximate the cardiac tissue. A first set of electromagnetic radiation is then directed from the distal end of the elongated body towards the cardiac tissue. Reflective and opaque surfaces at the distal end of the elongated body may be used to direct the electromagnetic radiation and an expandable membrane at the distal end may be used to urge the distal end of the elongated body to a predetermined position within the esophagus.Type: GrantFiled: December 31, 2007Date of Patent: December 1, 2015Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.Inventors: Saurav Paul, Israel A. Byrd
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Patent number: 9186066Abstract: An apparatus for applying a plurality of electro-magnetic radiations to a sample is provided. In one exemplary embodiment, the apparatus can include an arrangement which has a specific portion with a plurality of channels. One of channels can facilitate a first radiation of the radiations to be forwarded to the sample that is within an anatomical structure, and another one of the channels can facilitate a second radiation of the radiations to be forwarded to the sample. The first radiation may have a first wavelength band, and the second radiation may have a second wavelength band. The first wavelength band may be substantially different from the second wavelength band. According to another exemplary embodiment, the first radiation can be adapted to be delivered to a first area of the sample, and the second radiation may be capable of being delivered to a second area of the sample. The first area may be substantially enclosed by the second area.Type: GrantFiled: February 1, 2007Date of Patent: November 17, 2015Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc
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Patent number: 9179970Abstract: Methods of ablating tissue in an alimentary tract are provided. The methods include advancing an ablation structure into an alimentary tract while supporting the ablation structure with an endoscope. The methods further include a step of moving at least part of the ablation structure with respect to the endoscope and toward a tissue surface, before activating the ablation structure to ablate a tissue surface.Type: GrantFiled: July 12, 2011Date of Patent: November 10, 2015Assignee: Covidien LPInventors: David S. Utley, Robert Garabedian, Michael P. Wallace
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Patent number: 9168098Abstract: A light-based method of endovascular treatment, in particular, of pathologically altered blood vessels. Provided are a Method of Endovascular Light Treatment and a corresponding Endovascular Light Application Device.Type: GrantFiled: June 10, 2013Date of Patent: October 27, 2015Assignee: DORNIER MEDTECH LASER GMBHInventors: Tobias Beck, Richard Meier
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Patent number: 9089399Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.Type: GrantFiled: August 15, 2012Date of Patent: July 28, 2015Assignee: Katalyst Surgical, LLCInventors: Gregg D. Scheller, Craig Moore, Matthew N. Zeid
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Patent number: 8992514Abstract: A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both.Type: GrantFiled: February 21, 2013Date of Patent: March 31, 2015Assignee: Isolase, Ltd.Inventors: Omer Peled, A. Jason Mirabito
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Patent number: 8985121Abstract: A method and a device for minimally invasive treatment of diseased deep and superficial venous valves are disclosed. Treatment seeks to repair/rejuvenate dysfunctional valve by reducing the circumference of dilated valve rings and by restoring their original shape and function using laser energy to make physical suture points and shrink collagen in selected points. Real time monitoring is by angioscopic view and endovenous echographic control. In a preferred embodiment, system comprises a specific catheter-like device for endovenous insertion that allows for real time view of energy emission and venous surface to be corrected. Catheter flexibility is such that viewing angle and direct energy emission can be oriented properly. Catheter can comprise channels for irrigation or for interchange of laser fibers according to desired irradiation pattern. A preferred embodiment of catheter device also comprises cuffs for temporary occlusion, by inflation and deflation.Type: GrantFiled: May 6, 2011Date of Patent: March 24, 2015Assignee: Biolitec Pharma Marketing Ltd.Inventors: Enrique Ferracani, Wolfgang Neuberger
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Patent number: 8971997Abstract: An infrared fiber-optic device is able to monitor esophageal temperature during an ablation/cryoablation procedure over a volume of interest to sense whether the temperature is too high or too low. The device may include a plurality of optical fibers each with a wide angle lens collectively disposed circumferentially and longitudinally to cover the volume of interest, as the particular region over which undesirable temperature may not be known beforehand. In other examples, the device may include an embedded array of infrared sensors extending sufficiently to encompass a volume of interest. The device may be used as part of a feedback control to regulate and stop operation of the ablation/cryoablation procedure to prevent vessel damage.Type: GrantFiled: March 24, 2009Date of Patent: March 3, 2015Assignee: The Regents of the University of MichiganInventors: Hakan Oral, Fred Morady
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Patent number: 8951296Abstract: Devices and methods for therapeutic photodynamic modulation of neural function in a human. One embodiment of a method in accordance with the technology includes administering a photosensitizer to a human, wherein the photosensitizer preferentially accumulates at nerves proximate a blood vessel compared to non-neural tissue of the blood vessel. The method can further include irradiating the photosensitizer using a radiation emitter positioned within the human, wherein the radiation has a wavelength that causes the photosensitizer to react and alter at least a portion of the nerves thereby providing a therapeutic reduction in sympathetic neural activity. Several embodiments of the technology are useful for disrupting renal nerves, such as renal denervation, for treating hypertension, diabetes, congestive heart failure, and other indications.Type: GrantFiled: March 14, 2013Date of Patent: February 10, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Robert J. Melder, Ayala Hezi-Yamit, Christopher W. Storment, Carol M. Sullivan
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Patent number: 8888767Abstract: An improved method and device for safe and efficient medical applications is provided. In a preferred embodiment, based on using the inherent benefits of laser diodes (such as efficient power generation from a reliable and compact solid state device), plasmas and high energy vapors are produced for medical applications with power levels and power densities sufficient to treat medical indications and avoid the creation of extensive damage zones. Transmissions means in different configurations are used to achieve a high power density, which is able to initiate plasma and high-energy vapor at the tip. Once a sparkless plasma and high energy vapor bubbles are formed, it is often found that it will also absorb other wavelengths in addition to the one that initiated it. As a consequence, other wavelengths more efficiently generated by diodes or diode pumped lasers may be added into the beam in order to improve treatment efficiency.Type: GrantFiled: December 2, 2009Date of Patent: November 18, 2014Assignee: Biolitec Pharma Marketing LtdInventors: Wolfgang Neuberger, Walter Cecchetti
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Patent number: 8887733Abstract: An endovascular sheath device for use with a thermal treatment apparatus is provided. The device includes a longitudinal tube which is designed to receive a thermal treatment device and is designed to be inserted into a blood vessel. An ultrasonically visible reinforcement element is disposed along the length of the longitudinal tube. The reinforcement element such as a braided wire provides several functions including increased visibility under ultrasound, clearer identification of sheath tip, and increased durability to protect the fiber from needle punctures during tumescent injections into the perivenous space. The wire reinforcement also increases shaft torquability and kink resistance during sheath insertion and withdrawal.Type: GrantFiled: June 12, 2008Date of Patent: November 18, 2014Assignee: AngioDynamics, Inc.Inventors: William M. Appling, Lowell S. Kabnick
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Patent number: 8882754Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal pulmonary veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's pulmonary veins are provided.Type: GrantFiled: December 29, 2011Date of Patent: November 11, 2014Assignee: Volcano CorporationInventors: Joe E. Brown, Marja Pauliina Margolis, Mary L. Gaddis
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Patent number: 8882751Abstract: A medical device for removing a thrombus from a blood vessel and a process thereof is presented. The device includes an outer sheath with a plurality of lumens. A wire guide inserted through one of the lumens is used to place the device proximate to a thrombus. An optical fiber placed through a second lumen uses laser input to ablate the thrombus in the distal portion of the second lumen near its distal end. A vacuum coupled to the proximal end of the second lumen is used to remove any ablated residual material. The second lumen may be pivoted around the first lumen to reposition the second lumen proximate to an area of the thrombus that has not yet been ablated.Type: GrantFiled: September 9, 2008Date of Patent: November 11, 2014Assignee: Cook Medical Technologies LLCInventor: Frank J. Fischer, Jr.
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Publication number: 20140288541Abstract: Tissue and vessel treatment devices and respective methods are provided. Devices comprise a flexible treatment layer that comprises a plurality of operable elements configured to be activated to apply the treatment to the obstruction upon bending of the flexible treatment layer beyond a specified curvature threshold and to be de-activated upon a specified decrease of the bending. The treatment layer may comprise optical fiber(s) with the operable elements as emission regions that emit electromagnetic radiation from the core upon bending the optical fiber beyond a specified bending threshold. Devices may be configured as vessel sealing tips for surgical forceps, in which the treatment layer is configured to yield vessel welding and vessel cutting effects.Type: ApplicationFiled: June 2, 2014Publication date: September 25, 2014Applicant: ASYMMETRIC MEDICAL LTD.Inventors: Moshe ESHKOL, Ori WEISBERG
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Patent number: 8840606Abstract: An endovascular laser treatment device designed to be used with an optical fiber to treat venous diseases such as varicose veins is provided. The device includes a spacer that positions the distal end of the optical fiber away from the inner wall of the blood vessel during delivery of laser energy to provide an even distribution of thermal energy around the vessel, thereby avoiding vessel perforation and incomplete vessel collapse.Type: GrantFiled: March 26, 2013Date of Patent: September 23, 2014Assignee: AngioDynamics, Inc.Inventors: William M. Appling, Eamonn Hobbs
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Publication number: 20140276683Abstract: A system and devices for ablation and removal of occlusions from blood vessels is provided. Laser cutting systems and mechanical cutting systems are provided in catheter devices, the cutting systems operable to ablate, cut, dislodge, and otherwise remove occlusions within a blood vessel that may limit or prevent proper circulation. Catheter systems comprise distal end features adapted to cut and remove at least portions of an occlusion that generally correspond to dimensions of an inner lumen of a catheter.Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Applicant: The Spectranetics CorporationInventors: Brandon Thomas Hendrick, Kenneth P. Grace
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Publication number: 20140276682Abstract: Catheters for ablation and removal of occlusions from blood vessels are provided. Laser cutting systems and mechanical cutting systems are provided in catheter devices, the cutting systems operable to ablate, cut, dislodge, and otherwise remove occlusions within a blood vessel that may limit or prevent proper circulation. A helical or partially-helical inner surface structure is provided in the catheter, the structure operable to remove or translate dislodged material(s).Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Applicant: The Spectranetics CorporationInventors: Brandon Thomas Hendrick, Kenneth P. Grace
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Publication number: 20140276684Abstract: The present invention generally relates to methods for removing plaque from a vessel. The method can involve obtaining a first image of a blood vessel using a first imaging modality, obtaining a second image of the blood vessel using a second imaging modality, and coregistering the first and second images, thereby generating a coregistered data set. The method can further involve inserting an atherectomy catheter into the blood vessel and removing plaque from the vessel with the atherectomy catheter based on plaque identified in the coregistered set of data.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: VOLCANO CORPORATIONInventors: Scott Huennekens, Neil Hattangadi
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Publication number: 20140249517Abstract: The present invetion provides a method and apparatus for elimination of atherosclerosis from an artery. According to the present invetion the diseased artery is approached from external side and ablate is approached in such a way that incision/cut pass through tunica adventitia and tunica media of the diseased artery and a fibrous capsule of the atherselerosis. On ablation/incision, the contents plaques are exposed to the natural defense of the body and are destroyed by the natural defense system. The plaque escaping out of the artery on the external surface of the artery may be wiped or washed away with saline during or after the ablation procedure. Then, natural healing of artery is allowed which eliminates atherosclerosis thoroughly.Type: ApplicationFiled: October 12, 2012Publication date: September 4, 2014Inventor: Ajoy I. SINGH
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Publication number: 20140228828Abstract: Various embodiments of an eccentric balloon catheter are disclosed. In some embodiments, an eccentric balloon catheter includes an eccentrically positioned guidewire tube, with an interior lumen, that extends at least a portion of the length of the catheter body. Optical fibers may extend the length of the catheter body and may also be eccentrically positioned within the catheter body. An inflatable balloon may be positioned within a window within the catheter body near the distal end of the catheter. When inflated, the balloon and catheter may slide relative to one another. When used within a vessel, an inflated balloon may press against a vessel wall and bias the catheter toward an opposite vessel wall.Type: ApplicationFiled: February 7, 2014Publication date: August 14, 2014Inventor: Jacob Keeler
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Publication number: 20140194861Abstract: In some embodiments, without limitation, the invention comprises a catheter having an elongated housing with a channel disposed therein. A laser delivery member is movable and at least partially disposed within the channel. A ramp is disposed within the housing at an angle to its central axis and proximate to its distal end. The ramp is adapted to move the distal end of the laser delivery member outwardly from the central axis of the housing. A guidewire biases the distal end of the laser delivery member generally inwardly toward the central axis of the housing. In some embodiments, without limitation, the offset of the central axis of the tip of the laser delivery member from the central axis of the housing is determined by adjusting the extent to which the laser delivery member travels on the ramp, and disposition of the laser delivery member on the guidewire maintains the offset tip substantially parallel to the central axis of the housing.Type: ApplicationFiled: January 10, 2014Publication date: July 10, 2014Applicant: The Spectranetics CorporationInventors: Jacob Keeler, Melissa Brookshier
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Publication number: 20140188094Abstract: Focused infrared light may be used in a non-invasive varicose vein treatment procedure with infrared light from a plurality of laser diodes that are combined in a multiplexer and coupled to a multi-mode fiber coupled to another fiber or fiber bundle that delivers the light to a lens/mirror assembly for application in the non-invasive procedures. The wavelength of light may be selected near 980 nm, 1210 nm, or 1720 nm to achieve a desired penetration depth and/or for absorption in a particular tissue type or water. Wavelengths near approximately 1100 nm, 1310 nm or 1650 nm may be advantageous for non-invasive procedures through the skin. The light may be focused with lower intensity on the skin or outer tissue to reduce collateral damage and higher intensity at a desired depth to induce thermal coagulation or occlusion at depths of about 1-2 mm or more. Surface cooling techniques, such as cryogenic sprays or contact cooling may be provided.Type: ApplicationFiled: December 17, 2013Publication date: July 3, 2014Applicant: OMNI MEDSCI, INC.Inventor: Mohammed N. Islam
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Patent number: 8758333Abstract: Embodiments of the present invention comprise a fiber optic guidewire having a hypotube with a plurality of openings that provide variable stiffness and tracking characteristics between at least one proximal segment and one distal segment of the guidewire. In some embodiments, the guidewire further comprises a mandrel disposed within the hypotube, the mandrel cooperating with the optical fibers to permit the distal end of the hypotube to be shaped as desired by a user. Methods of manufacturing and using the guidewire are also disclosed.Type: GrantFiled: April 4, 2007Date of Patent: June 24, 2014Assignee: The Spectranetics CorporationInventor: Kenneth D. Harlan
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Patent number: 8747389Abstract: Devices, systems and methods useable for dilating the ostia of paranasal sinuses and/or other passageways within the ear, nose or throat. A dilation catheter device and system is constructed in a manner that facilitates ease of use by the operator and, in at least some cases, allows the dilation procedure to be performed by a single operator. Additionally, the dilation catheter device and system may be useable in conjunction with an endoscope and/or a fluoroscope to provide for easy manipulation and positioning of the devices and real time visualization of the entire procedure or selected portions thereof. In some embodiments, an optional handle may be used to facilitate grasping or supporting a device of the present invention as well as another device (e.g., an endoscope) with a single hand.Type: GrantFiled: April 24, 2007Date of Patent: June 10, 2014Assignee: Acclarent, Inc.Inventors: Eric Goldfarb, John Y. Chang, William M. Facteau, Sivette Lam, Hung V. Ha, Isaac J. Kim, Ketan P. Muni
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Patent number: 8734436Abstract: The invention is directed to a laser catheter (1) for bypass surgery, wherein the distal part (2) of the catheter (1) is provided with: a tubular arrangement (3) of optical fibers (4) having distal ends (5) defining a ring-shaped light emergence surface (6) for emitting a tubular bundle of light beams in the distal direction (D) of the catheter (1); and a stop surface (7) extending around the tubular arrangement (3) of optical fibers (4) and facing in the distal direction (D), the stop surface (7) being arranged at a distance (A) proximally from the light emergence surface (6). The light emergence surface (6) slants at a slanting angle (?) in the range of [20°, 60°] with respect to the longitudinal axis (8) of the catheter (1). The invention further relates to an assembly comprising such a catheter.Type: GrantFiled: February 21, 2008Date of Patent: May 27, 2014Assignee: AMJ bvInventor: Cornelis Antonius Franciscus Tulleken