Abstract: A surgical light for illuminating a target with light that has a reduced contribution of a portion of the visible spectrum includes a first light source configured to emit light having a first spectrum; a second light source configured to emit light having a second spectrum that does not include the portion of the visible spectrum; and a controller configured to simultaneously activate the first and second light sources for illuminating the target with light that has a reduced contribution of light in the portion of the visible spectrum relative to white light.

Abstract: Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

Abstract: Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

Abstract: Apparatus and methods for electrosurgery are disclosed. In one arrangement, an electrosurgical element and a control system are provided. The electrosurgical element is electrically driven in a first electrical driving mode. The first electrical driving mode is such as to cause heating of human or animal tissue by the electrosurgical element. The heating contributes to modification or cutting of tissue by the electrosurgical element. The electrosurgical element is electrically driven in a second electrical driving mode. An electrical response of the electrosurgical element is measured during the electrical driving of the electrosurgical element in the second electrical driving mode.

Abstract: A multifiber assembly and methods of using the same in an endoscopic procedure for transmitting illumination light to, and a response signal reflected from, a target is disclosed. An exemplary device comprises a proximal end, and distal end, and a transition section between the proximal and distal ends. The proximal end includes a first connector to be connected to a light source and a second connector configured to be connected to a spectrometer. The distal end includes a shaft including at least two first optical fibers to transmit light and at least one second optical fiber to transmit a spectroscopic signal. The transition section can couple the first connector to the at least two first optical fibers, and to couple the second connector to the at least one second optical fiber.

Abstract: An antimicrobial treatment system comprises a wearable photoactivation device. The wearable photoactivation device includes a body configured to be positioned on a head of a subject over one or more eyes of the subject. The body includes one or more windows or openings that allow the one or more eyes to see through the body. The body includes one or more photoactivating light sources coupled to the body and configured to direct photoactivating light to the one or more eyes according to illumination parameters. The illumination parameters determine a dose of the photoactivating light that activates, according to photochemical kinetic reactions, a photosensitizer applied to the one or more eyes and generates reactive oxygen species that provide an antimicrobial effect in the one or more eyes, without substantially inducing cross-linking activity that produces biomechanical changes in the one or more eyes.

Abstract: A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.

Abstract: Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

Abstract: Various implementations of visual inspector attachments for fiber connector cleaners are disclosed. The example fiber optic inspection module includes a camera to capture an image of an end-face, a light source to illuminate the end-face, and a first mirror that reflects light from the light source to the end-face and includes a fixed point that allows the first mirror to pivot. Alternatively, an example fiber optic inspection module includes a camera to capture an image of an end-face, a light source to illuminate the end-face, and a first mirror that reflects light from the light source to the end-face and the first mirror moves in an upward direction.

Abstract: The provided is a handpiece for skin laser treatment and a medical laser treatment apparatus including the same. The disclosed handpiece for skin laser treatment may include a handpiece body including a laser irradiation portion for irradiating a laser beam to a treatment target area of the skin of a person to be treated and a refrigerant spraying portion for spraying a refrigerant in the treatment target area; and an end tool member provided at an end of the handpiece body and configured to maintain a distance between the laser irradiation portion and the skin in contact with the skin of the person to be treated and to at least partially limit a target area corresponding to the treatment target area.

Abstract: Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

Abstract: A device for generating singlet oxygen is provided. The device has a sensitizer that converts triplet oxygen to single oxygen upon exposure to light. The device is configured to keep the sensitizer from contacting external fluids.

Abstract: The invention relates to combined liposuction methods and can be used in surgical interventions to remove local fat deposits in the lower third of the face and neck. The method includes a preoperative examination of the patient when one or more areas of the lower third of the face and neck of the patient are designated as liposuction areas constituting the operative field. The contour boundaries of the operative field and at least one operative access point are determined. Uniform infiltration anesthesia of the adipose tissue to be removed in the liposuction areas is performed. From a Nd:YAG laser radiation source with a wavelength of 1064 nm, a Nd:YAG laser radiation with a wavelength of 1064 nm in a pulsed mode with a frequency of 50 Hz, with a pulse duration of 300 ?s and a power of the predetermined value is supplied directly to the adipose tissue to be removed.

Abstract: The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets. The method of treatment is performed and then, depending upon the desired clinical outcome, repeated after a treatment response interval has elapsed.

Abstract: A sensor arrangement/evaluation which allows piercing detection within a fiber optic cable connector by means of two photodetectors independent of power, pulse frequency and pulse length.

Abstract: Light energy is applied externally to a patient's head, neck, or both, to treat the brain and nervous system. The light energy stimulates different neurological pathways, reduces inflammation, stimulates mitochondria function in the brain, and increases HRV. The light is applied to the patient on the skull, near the vagus nerve, or a combination thereof. The treatment can be enhanced by activating the cranial nerves while the light is applied. The wavelengths of the applied light range from ultraviolet to far infrared, and preferably are visible light from about 400-760 nm. In a preferred embodiment the applied light is in the red range and more preferably about of 635 nm±10 nm. The applied light energy is applied with a pulse frequency or frequencies that mimic healthy brain function of alpha, beta, delta, and theta waves such as 8 Hz, 53 Hz, 73 Hz and 101 Hz. The pulse frequencies can be applied singularly, serially, alternately, or simultaneously.

Abstract: A wearable photobiomodulation device comprises a shell portion and an illumination module and is configured to deliver light to a photoresponsive tissue of an individual. In some embodiments, the illumination module provides red and/or infrared light to a photoresponsive tissue on an individual at a dose of between about 5-50 mJ/cm2 over a target illumination area of about 100-200 cm2. Exemplary devices may be configured as a wearable sports cup with an integral or detachable illumination module that provides effective amounts of light to a target are to so effect photobiomodulation in an individual wearing the device.

Abstract: To provide a light diffuser plate that can control an anisotropic shape of diffused light. The light diffuser plate includes a base material, and a group structure including a plurality of convexities or concavities provided on at least one main surface of the base material and having anisotropic shapes extended in a common direction. The plurality of convexities or concavities are arranged randomly and densely on the main surface of the base material. A boundary between adjacent ones of the plurality of convexities or concavities includes a plurality of curved lines having curvatures different from each other.

Abstract: A sensor arrangement/evaluation which allows piercing detection within a fiber optic cable connector by means of two photodetectors independent of power, pulse frequency and pulse length.

Abstract: System and methods to generate and control light for use in therapeutic, aesthetic, disinfection, and other light-related applications in settings where a significant portion of skin is exposed to light (e.g., shower, sauna, locker-room). Characteristics of the light are controlled to simulate specific spectra of natural sunlight and unnatural light and deliver targeted doses of UV light (e.g., for vitamin-D synthesis, boosting the immune system, tanning), UV-C light (e.g., to kill bacteria, viruses, and fungi), visible light (e.g., to anchor a circadian rhythm to improve mood, metabolism, cognitive functions, physical performance, and sleep), and red or infrared light (e.g., for skin rejuvenation, wound healing, tissue repair, blood-flow, muscle recovery, circulation) while, at the same time, minimizing negative impacts of light exposure. Various embodiments may further create the experience of an outdoor shower.

Abstract: A device for shaping tissue includes a tip with an internal close-looped circulation system. The tip is configured to connect to tubes. One tube is configured to connect to a submersible cold-water pump. Another tube is an outlet. The tip has a sapphire window on one face and, on opposite face, a shaft with a laser fiber therein, and an opening for laser beam to shine through.

Abstract: A hand-held light treatment device configured with interchangeable emitter heads that are pre-programmed with desired treatment protocols and updated from a remote store of treatment protocols. The device comprises a handpiece, a plurality of emitter heads, and a base. The removable emitter heads each contain one or more treatment LEDs, a tracking light, a task light, a proximity sensor, and a control module. A tip is attached to the emitter head, either removably or integral therewith. In one embodiment, the tip is integral with the emitter head and emits light to the side of the device, perpendicular to the handpiece. The device is prohibited from emitting light when too far from a surface. Some embodiments have disposable tips of various shapes that attach to the emitter heads, which permits a single device to direct the emitted energy at nearly any direction and be used in a variety of applications.

Abstract: The present disclosure provides methods and compositions for the treatment of oral lesions in a subject comprising a methylene blue oral rinse.

Abstract: Embodiments of this disclosure disclose an imaging system, including an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The beam source generates an electromagnetic radiation beam. The detection assembly generates a signal indicative of an intensity of a portion of the electromagnetic radiation beam reflected from the focal point location. A subsequent focal point of the electromagnetic radiation beam may be adjusted per the measured intensity signal. In some embodiments, an intensity signal below a lower threshold value may suggest a depth increase for a subsequent focal point. An intensity signal above an upper threshold value may suggest a depth decrease for a subsequent focal point. And, an intensity signal between the lower and upper thresholds may suggest a depth be maintained for a subsequent focal point. The focal point may be adjusted after each pulse or after a plurality of pulses.

Abstract: A device includes light sources, electromagnetic field generators, and vibration components to apply a variety of treatment regimens to a living animal organism, including a human person or a body part of a person. The light and electromagnetic therapy are applied at frequencies which have physiological effects, and which can be combined to induce lipolysis, stimulate muscle, and achieve other effects. Feedback is used to dynamically adjust the intensity, duration, and other parameters of the light, electromagnetic, and vibration treatment modalities.

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: The present invention provides for oral care systems comprising: an appliance comprising a first and second plurality of nozzles, the appliance configured to be held in the mouth of a user with the first and second plurality of nozzles in fluid communication with one or more surfaces of the user's oral cavity; a source of gas; a source of liquid; and a fluid controller for directing entrained fluid to the appliance. Also provided are methods of cleaning, or otherwise providing benefits to, one or more surfaces of the oral cavity using a system of the present invention.

Abstract: Electrosurgical lysing devices and related systems and methods. In some embodiments, the lysing device may comprise a lysing tip comprising a plurality of beads. One or more of the plurality of beads may be electrically non-conductive, at least along their respective surfaces. The lysing tip may further comprise at least one lysing member defining at least one lysing segment extending between each pair of adjacent beads. At least a subset of the plurality of beads may protrude both distally and proximally relative to the at least one lysing member.

Abstract: The invention provides a laser system and method for administering multiple beams of laser energy in tissue treatment applications. The system administers the beams simultaneously in a distribution pattern of spatially separated overlapping and non-overlapping regions on a tissue. The simultaneous administration and distribution pattern permit the beams to propagate within a tissue without producing the light scattering effects that characterize the sequential application of multiple laser beams to a tissue.

Abstract: The apparatus for irradiating a laser in accordance with an exemplary embodiment includes: a main body; a laser resonator located within the main body and configured to generate a laser beam and output the laser beam forwards; a beam barrel in which a focusing lens is fixed; a beam barrel guiding unit located in front of the main body and configured to guide forward and backward movement of the beam barrel; and a forward and backward moving means connected to an outer periphery of the beam barrel and configured to move the beam barrel forwards and backwards relative to an irradiation target portion in front of the beam barrel. A screw thread is formed on the outer periphery of the beam barrel and a screw thread is formed on an inner surface of the forward and backward moving means.

Abstract: Method and apparatus for illuminating and imaging tissue is provided. In one version, the method includes illuminating a volume of a tissue with photons from a three-dimensional array of optical emitters inserted into the tissue. In another version, the method includes detecting photons from a volume of a tissue using a three-dimensional array of optical detectors inserted into the tissue. A probe device for illuminating tissue and/or detecting photons emitted from tissue includes elongated microsized probes containing optical emitters and optical detectors in a three dimensional array.

Abstract: The present invention provides method and apparatus for treating tissue in a region at depth while protecting non-targeted tissue by cyclically applying cooling to the patients skin, and preferably to the region, and by applying radiation to the patient's skin above the region to selectively heat tissue during and/or after cooling is applied. At least one of cooling and radiation may be applied by successively passing a continuous output applicator over the patient's skin. Treatment may also be enhanced by applying mechanical, acoustic or electrical stimulation to the region.

Abstract: A motion capture system includes a motion sensor having a flexible body and a fiber bragg gratings (FBG) sensor inserted into the body, a fixture configured to fix the motion sensor to a human body of a user, a light source configured to irradiate light to the motion sensor, and a measurer configured to analyze a reflected light output from the motion sensor, wherein the FBG sensor includes an optical fiber extending along a longitudinal direction of the body and a sensing unit formed in a partial region of the optical fiber and having a plurality of gratings, and wherein a change of a wavelength spectrum of the reflected light, caused by the change of an interval of the gratings due to a motion of the user, is detected to measure a motion state of the user.

Abstract: Some embodiments include apparatuses and methods using the apparatuses. Some of the apparatuses include a circuit structure that can be configured to operate in either the C-PHY mode or the D-PHY mode of the MIPI specification. In one device, the circuit structure can be included in a receiver of the device and configured to operate in the C-PHY mode. In another device, the circuit structure can be included in a receiver of the device and configured to operate in the D-PHY mode.

Abstract: A lighting system combines an arrangement of UV LEDs which face a light exit window and an arrangement of visible light LEDs which face a reflector arrangement. The reflection can be used to provide desired beam shaping or diffusion so that beam shaping components are not needed at the exit window. In this way, UV deterioration of beam shaping components is avoided.

Abstract: Embodiments of this disclosure disclose an imaging system, including an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The beam source generates an electromagnetic radiation beam. The detection assembly generates a signal indicative of an intensity of a portion of the electromagnetic radiation beam reflected from the focal point location. A subsequent focal point of the electromagnetic radiation beam may be adjusted per the measured intensity signal. In some embodiments, an intensity signal below a lower threshold value may suggest a depth increase for a subsequent focal point. An intensity signal above an upper threshold value may suggest a depth decrease for a subsequent focal point. And, an intensity signal between the lower and upper thresholds may suggest a depth be maintained for a subsequent focal point. The focal point may be adjusted after each pulse or after a plurality of pulses.

Abstract: A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, the at least one light emitter adapted to emit light of at least two different wavelengths. The system also includes at least one light sensor disposed at the working end of the surgical instrument opposite the at least one light emitter, the at least one light sensor adapted to detect light at the at least two different wavelengths. The system further includes a controller coupled to the at least one light sensor and adapted to determine a ratio of the light absorbed at the least two different wavelengths, and to indicate if an artifact within a region proximate to the working end of the surgical instrument is a vessel based on the ratio.

Abstract: Stage light fixture provided with: a short arc lamp adapted to emit a light beam along an optical axis; a reflector associated to the short arc lampso as to concentrate light beam rays substantially at a work point; an output optical assembly, arranged at the most downstream point along the optical axis, having a focal point arranged between the light source and the output optical assembly and coinciding with the work point; at least one color assembly comprising a plurality of color devices configured to selectively color the light beam; the color assembly being arranged between the short arc lampand the work point (PL).

Abstract: A method of soft tissue treatment of a patient includes placing an applicator onto a surface of the soft tissue, with the applicator including an electrode and a dielectric material vacuum cup. The soft tissue is heated via the electrode. Vacuum is applied to the vacuum cup. The electrode may be at least partially covered by a dielectric material of variable thickness.

Abstract: A method, system and device for shortening hair with the method including generating a plurality of laser pulses overlapping in time; focusing the laser pulses into spatially separated focal spots having a peak power density at least equal to a first threshold at which a laser induced optical breakdown phenomenon occurs in the hair and below a second threshold at which a laser induced optical breakdown phenomenon occurs in skin. Generating the plurality of laser pulses includes an act of generating the plurality of laser pulses to reach the first characteristic threshold value after a start of each corresponding laser pulse in a time span of less than half of the pulse duration; and positioning the respective at least three focal spots into respective target positions within a single hair such that only one of the plurality of laser pulses occur in each of the at least three focal spots.

Abstract: A light-emitting device includes a plurality of light-emitting elements or light sources and a flexible pad for positioning and conforming the light-emitting device to a portion of a body of a user. The flexible pad includes a three-dimensional structure having a plurality of protrusions for contacting a skin of the portion of the body when the light-emitting device is applied to the portion of the body by the flexible pad. Further, the three-dimensional structure includes a plurality of recesses for creating a clearance between the skin and the flexible pad when the light-emitting device is applied to the portion of the body, and a plurality of apertures for engaging with the plurality of light-emitting elements. Each protrusion includes an extended part and a withdrawn part, where the extended part is further extended than the withdrawn part, and the extended part is configured to contact the skin.

Abstract: Provided is a color light therapy device. The color light therapy device includes: a body that is used by being attached to a color light therapy portion of a human body by using a double-sided adhesive tape, a hydrogel pad, or an air suction plate, and includes a printed circuit board (PCB) that supplies driving power to a light source that emits color light in a given wavelength range to perform color light therapy on the human body; and a power jack that is connected to the PCB of the body through an electric wire. Since a user may use the color light therapy device by connecting the power jack to a mobile phone, a PC, a laptop, a tablet PC, a smartphone, a personal digital assistant (PDA), a vehicle, or a socket at home while carrying the color light therapy device, anyone may conveniently use the color light therapy device to perform color light therapy on the human body without exchanging or charging a battery.

Abstract: A surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a target region; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the target region; and a OCT imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SS-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.

Abstract: Provided is a living body stimulator capable of bringing about a stable treatment effect through a light stimulation without increasing the temperature of an irradiation surface more than necessary. This invention is a living body stimulator for stimulating a living body through a light irradiation from a light source. This stimulator includes a temperature sensor for detecting the temperature of the irradiation surface in contact with the living body; and a brightness control unit for changing and controlling the brightness of the light source such that the temperature of the irradiation surface becomes not higher than 42° C., by receiving a detection output from the temperature sensor. The brightness control unit is capable of extending a period of irradiation from the light source in accordance with a decrease in the brightness thereof, when decreasing such brightness through a control regulation.

Abstract: An instrument system that includes an image capture device, an elongate body, an optical fiber and a controller is provided. The elongate body is operatively coupled to the image capture device. The optical fiber is operatively coupled to the elongate body and has a strain sensor provided on the optical fiber. The controller is operatively coupled to the optical fiber and adapted to receive a signal from the strain sensor and to determine a position or orientation of the image capture device based on the signal.

Abstract: A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland.

Abstract: The invention encompasses a method of inhibiting the growth of hair in skin including epilation of follicles in the skin, waiting until within 5 days of the commencement of metanagen, applying a photodynamic agent to the skin, and exposing the skin to photoactivating light.

Abstract: Providing a method for monitoring an analyte extracted from a patient and delivering a permeant composition to the patient. The method includes the steps of a) contacting a poration device to a tissue membrane of the patient, the poration device including at least one porator array; b) actuating poration of the tissue membrane using the at least one porator array in the poration device; c) extracting the analyte from the porated tissue membrane by way of the at least one porator array; d) analyzing the analyte to determine a concentration of the analyte within the tissue membrane; and e) delivering a permeant composition to the tissue membrane by way of the at least one porator array.

Abstract: A cataract surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a cataract target region in an eye; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the cataract target region; and a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SD-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.