Absorbable Patents (Class 606/77)
  • Patent number: 10357372
    Abstract: A radial head trial device for replacement of a proximal radial head includes a stem component having a center longitudinal axis extending between a proximal end and a distal end, a head component axially and removably attachable to the stem component, wherein the head component is interchangeable with a selection of other head components each axially and removably attachable to the stem component, an anti-rotation feature, and a recess, wherein the anti-rotation feature is structured to be received in the recess to prohibit rotation of the head component relative to the stem component.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: July 23, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: James Brownhill, Andrew Rynearson
  • Patent number: 10226247
    Abstract: An exemplary surgical staple may include a base including a first end and a second end; a single tine extending from the second end of the base; and a barb extending from the base at a location between the first end of the base and the second end of the base. An end of such a staple may be frangibly affixed to a feeder belt. Another exemplary surgical apparatus may include at least one staple including a base including a first end and a second end, a first tine extending from the second end of the base, and a second tine extending from the base at a location between the first end of the base and the second end of the base.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 12, 2019
    Assignee: Aesculap AG
    Inventors: Philipe R. Manoux, Bryan D. Knodel
  • Patent number: 9907663
    Abstract: An implant system includes a first portion, a second portion, and a third portion. The first portion includes a hydrogel. The second portion includes a porous material and the hydrogel in pores of the porous material. The third portion includes the porous material. The first portion is free of the porous material. The third portion is free of the hydrogel. Methods of making and using the implant system.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: March 6, 2018
    Assignee: Cartiva, Inc.
    Inventors: Timothy J. Patrick, Carribeth B. Ramey, Letitia Tudor, Michael A. Axelrod
  • Patent number: 9889238
    Abstract: A biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: February 13, 2018
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, James Oberhauser, Xiao Ma
  • Patent number: 9700652
    Abstract: A medical implant comprising a composite material which is composed of reinforcement fibers made of a magnesium-containing, bio-corrosive alloy, another bio-corrosive alloy containing a main component that is selected from the group consisting of Mg, Ca, Fe, and Y, or a non-biodegradable fiber material, embedded in a matrix made of crystalline magnesium or magnesium alloys.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: July 11, 2017
    Assignee: BIOTRONIK VI PATENT AG
    Inventors: Joerg Loeffler, Heinz Mueller, Peter Uggowitzer, Gerhard Kappelt
  • Patent number: 9700414
    Abstract: An osteotomy implant including a porous portion, a solid portion, and a hinge portion. The porous portion includes a first part and a second part that defines a clearance therebetween. A solid portion abuts the porous portion. A hinge portion of the solid portion is coupled to the first part and the second part. The hinge portion is configured to enable the implant to be changed from a first configuration to a second configuration.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: July 11, 2017
    Assignee: Biomet sports Medicine, LLC
    Inventors: William Maxson, Gautam Gupta
  • Patent number: 9439685
    Abstract: A multi-layer osteogenic, osteoconductive and/or osteoinductive carrier device or system for applying an osteoinductive substance to a bone surface, and methods for making and using said carrier are disclosed. The multi-layer osteogenic carrier device can comprise a delivery layer comprising a porous material and an osteogenic material; and a support layer in communication with the delivery layer, the support layer capable of substantially conforming to an anatomical feature, wherein the support layer can hold the delivery layer in proximity to the anatomical feature. The multi-layer osteogenic carrier device can further comprise an adhesive layer capable of adhering the carrier to at least a portion of an anatomical feature, the adhesive layer in communication with at least a portion of the delivery layer. The carrier can be applied to and compressed to conform to the decorticated bone of a fusion site and kept in place by a rod clip attached to a spinal stabilization system.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: September 13, 2016
    Assignee: BULLARD SPINE, LLC
    Inventor: Dennis E. Bullard
  • Patent number: 9408949
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: August 9, 2016
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Eugene T. Michal, Thierry Glauser, Stephen D. Pacetti, Jessica DesNoyer
  • Patent number: 9402669
    Abstract: A method for producing a medical implant, such as a bone screw, a bone nail, a bone pin, a plate, a suture anchor, etc. for fastening soft parts, such as tendons, muscles, and ligaments, to a bone, or in the form of an endoprosthesis or at least a part thereof, from a magnesium alloy having a magnesium fraction of at least 80 wt %, in particular of at least 90 wt %, including the following steps: a) melting the magnesium alloy to obtain an alloy melt, b) atomizing the alloy melt under a protective-gas atmosphere and cooling the atomized alloy melt to below the solidification point thereof in order to obtain an alloy powder, c) shaping the alloy powder by pressing to obtain an alloy green body, d) extruding the alloy green body to obtain a magnesium alloy molded part, and e) producing the medical implant from the magnesium alloy molded part.
    Type: Grant
    Filed: August 28, 2012
    Date of Patent: August 2, 2016
    Assignee: Syntellix AG
    Inventors: Volkmar Neubert, Robert Schavan
  • Patent number: 9387277
    Abstract: A bone replacement filler comprising a biomedical ceramic particulate, wherein the filler is able to flow without the application of an external shear stress or compressive force or under a relatively low shear stress or compressive force, but resists flow or does not flow when subjected to a higher shear stress or compressive force, and wherein at least some of the particles in the ceramic particulate have a micro-porous surface structure and/or a micro-porous sub-surface structure.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: July 12, 2016
    Assignee: ApaTech Limited
    Inventors: Thomas Buckland, Jonathan Arcos
  • Patent number: 9125719
    Abstract: Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties.
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: September 8, 2015
    Assignee: Tepha, Inc.
    Inventors: David P. Martin, Said Rizk, Ajay Ahuja, Simon F. Williams
  • Patent number: 9005250
    Abstract: A method of supporting a defect in the tissue of a living being includes the steps of: a) providing a delivery instrument that includes an elongated instrument, at least one barrier element, and a plurality of connecting members; b) inserting the elongated instrument into the tissue at or near the defect; c) deploying the barrier element from the delivery instrument into tissue at or near the defect, the barrier element having at least one connecting member attached thereto; d) extending at least one passage means from the delivery instrument; e) engaging at least a portion of the at least one connecting member with the at least one passage means, whereby the at least one passage means causes the at least one connecting member to pass through the tissue, and f) withdrawing the elongated instrument from the tissue, thereby deploying and securing the barrier element to support the tissue.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: April 14, 2015
    Assignee: Kensey Nash Corporation
    Inventor: Douglas G. Evans
  • Patent number: 8911440
    Abstract: An osteosynthesis device that is both resorbable and radiopaque, produced using gradually degrading materials, includes at least one plate and a set of screws made of resorbable material, in which the plate consists of a composite mixture including i) a resorbable polymer or copolymer compound and ii) an inorganic filler that consists of at least one resorbable ceramic. The screws can be made of resorbable polymer, or of a composite mixture with at least one resorbable ceramic. The device is totally resorbable and radiopaque, and it offers a high level of safety, ensuring a strong and durable fixation of the screws to the plate and in the bone during the entire period needed for bone uniting.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: December 16, 2014
    Assignee: Teknimed
    Inventors: Alain Leonard, Carole Leonard, Cyril Sender, Olivier Lignon, Gautier Halbin, Nouredine Sahraoui
  • Patent number: 8840613
    Abstract: Methods of reducing device drag on implantable articles are disclosed herein. The methods include coating the contact surfaces of implantable articles with bioabsorbable lubricating coatings.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: September 23, 2014
    Assignee: DePuy Mitek, LLC
    Inventors: Mark B. Roller, Joseph H. Contiliano, Kevin L. Cooper, Jo Hays, Jenny J. Yuan
  • Publication number: 20140236155
    Abstract: A method for producing a medical implant, such as a bone screw, a bone nail, a bone pin, a plate, a suture anchor, etc. for fastening soft parts, such as tendons, muscles, and ligaments, to a bone, or in the form of an endoprosthesis or at least a part thereof, from a magnesium alloy having a magnesium fraction of at least 80 wt %, in particular of at least 90 wt %, including the following steps: a) melting the magnesium alloy to obtain an alloy melt, b) atomizing the alloy melt under a protective-gas atmosphere and cooling the atomized alloy melt to below the solidification point thereof in order to obtain an alloy powder, c) shaping the alloy powder by pressing to obtain an alloy green body, d) extruding the alloy green body to obtain a magnesium alloy molded part, and e) producing the medical implant from the magnesium alloy molded part.
    Type: Application
    Filed: August 28, 2012
    Publication date: August 21, 2014
    Applicant: SYNTELLIX AG
    Inventors: Volkmar Neubert, Robert Schavan
  • Patent number: 8715286
    Abstract: Implants, such as interbody spacers, fusion devices and bone grafts, are provided having improved mechanical properties and/or degradation profiles. Such implants include a three-dimensional scaffold formed from particles, such as microspheres, which may in some embodiments be resorbable or biodegradable and which may have at least two different degradation rates. In some embodiments, the scaffold may be elastomeric. The three-dimensional scaffold may be for example, porous or semi-porous. Also provided are kits including such implants, and methods of producing and using the same.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: May 6, 2014
    Assignee: Globus Medical, Inc.
    Inventor: Mark Borden
  • Patent number: 8709082
    Abstract: A method of performing a surgical anterior extradiscal correction of a thoracolumbar pathology includes steps of surgically approaching a patient's spine and correcting a thoracolumbar pathology, aligning adjacent vertebral bodies, and securing the vertebral bodies in a desired relative position with anterior instrumentation that penetrates at least one of the vertebral bodies. The anterior instrumentation includes a bioabsorbable element and in one embodiment includes first and second bioabsorbable anchors for penetrating anterior portions of respective first and second sacral, thoracic or lumbar vertebral bodies and bioabsorbable instrumentation that fixedly connects the first bioabsorbable anchor to the second bioabsorbable anchor. This permits the first sacral, thoracic or lumbar vertebral body to be surgically fixed to the second sacral, thoracic or lumbar vertebral body for a predetermined period of time, when the bioabsorbable apparatus will be absorbed by a patient's body.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: April 29, 2014
    Assignee: K2M, Inc.
    Inventor: Robert W. Gaines, Jr.
  • Patent number: 8680498
    Abstract: A method for utilizing an implant in a human breast includes forming a breast cavity within the breast at a lumpectomy site, the breast cavity having surrounding tissue; forming a substantially radio-opaque implant constructed of biocompatible and biodegradable material configured to allow for in-growth of fibrous tissue into and replacing the biocompatible and biodegradable material, the biocompatible and biodegradable material being elastically compressible; sizing the substantially radio-opaque implant to occupy the breast cavity; and implanting within the breast cavity the substantially radio-opaque implant to support the tissue surrounding the breast cavity, the step of implanting including compressing the biocompatible and biodegradable material.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: March 25, 2014
    Assignee: SenoRx, Inc.
    Inventors: John Corbitt, Lori Anthony
  • Patent number: 8672986
    Abstract: A device for temporarily splinting toes, especially for the treatment of hammertoes and other defective positions of toes, consisting of a tube composed of a bio-absorbable material and a guide wire. The tube has an inner diameter of d, whereas the guide wire has an external diameter D, such that D<d. The device enables contact between the ball of the toe and the floor to be reestablished.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: March 18, 2014
    Assignee: Depuy Synthes Products, LLC
    Inventors: Kaj Klaue, Hans Zwipp, Patrick Cronier, Andrew K. Sands
  • Publication number: 20130317504
    Abstract: Orthopedic implants having improved strength and imaging characteristics are provided. The implants can comprise an inner core member that is encased at least in part by an outer encasing member. The inner core member can be formed of a first material that imparts improved strength to the implant, while the outer encasing member is formed of a second material that imparts improved imaging characteristics to the implant. Alternatively, the implants can include a single-piece member formed of a first material that is coated by a coating layer of a second material.
    Type: Application
    Filed: May 23, 2012
    Publication date: November 28, 2013
    Inventors: David C. Paul, William S. Rhoda
  • Patent number: 8560052
    Abstract: Echogenic medical devices, methods of fabrication and methods of use are disclosed. The device can be adapted to be inserted into a patient. The echogenic construction can be incorporated into the device at the time of fabrication providing acoustic impedance different from that of the surrounding biological tissue or fluid. The medical device is designed for use with an ultrasound imaging system to provide real-time location of the insertion and guidance at the time the device is implanted in a patient, such as in brachytherapy. Following placement of the device the position can be evaluated over time to insure the device remains in proper alignment and functional. Furthermore, the device is designed to incorporate a spacer element at one or both ends to provide separation between radioactive elements.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: October 15, 2013
    Assignee: Core Oncology, Inc.
    Inventor: Stanley L. Mills
  • Patent number: 8541764
    Abstract: A method of partial breast radiation therapy includes placing within a breast cavity a substantially radio-opaque implant constructed of biocompatible material, said substantially radio-opaque implant supporting the tissue surrounding the breast cavity; and directing a radiation beam to said substantially radio-opaque implant serving as a target for delivery of radiation therapy to margins around the breast cavity, such that the radiation beam does not materially irradiate the whole of the breast.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: September 24, 2013
    Assignee: Senorx, Inc.
    Inventors: John Corbitt, Lori Anthony
  • Patent number: 8506608
    Abstract: An orthopedic screw is used in a fixation device for treating fractures. The device has a body with holes to accept the bone screws. The bone screws have a layer of bioresorbable material on the shaft. Engagement between the bone screws and the body is initially through the bioresorbable material, which engagement rigidly fixes the relative angular orientation between the bone screws and the body when the device is applied to a bone. As the bioresrobable material is resorbed the angular relation between the bone screws and the body is no longer rigidly fixed, thereby effecting a transformation from rigid osteosynthesis to flexible osteosynthesis to allow micromotion between the bone fragments which promotes healing.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: August 13, 2013
    Inventors: Douglas Cerynik, Susan P. Harding
  • Patent number: 8449584
    Abstract: A bone anchor is provided that can toggle in two planes for secure anchorage within a bone cavity. The bone anchor includes an oblique suture channel configured such that a suture strand extending through the bone anchor can be tensioned to toggle the bone anchor inside the bone cavity. The suture strand can be located on the same side of the anchor body to maximize the area of the anchor surface which engages bone, resulting in increased engagement into bone and resistance to tensile forces.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: May 28, 2013
    Assignee: DePuy Mitek, LLC
    Inventors: Lisa M. Donnelly, Edwin C. Bartlett, Karl S. Reese, Steven D. Muller, Paul J. Ares
  • Patent number: 8439952
    Abstract: The invention provides a connecting rod for bone anchors such as pedicle screws. The rod is constructed to include a main shaft portion that is not bioresorbable and a tip portion that is bioresorbable. The tip facilitates percutaneous insertion into a patient's body. After placement of the rod, the bioresorbable tip is resorbed preventing post-operative complications such as impingement of adjacent spinal facet joints.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: May 14, 2013
    Assignee: Integrity Intellect, Inc.
    Inventors: Wyatt Drake Geist, Christopher Walsh
  • Patent number: 8394128
    Abstract: A constraining apparatus includes a constraining structure that captures a first and a second anatomical structure. A motion limiting member coupled with the constraining structure is adapted to provide a force resistant to relative movement of the first anatomical structure away from the second anatomical structure. A regulating member is detachably coupled with the motion limiting member or the constraining structure and is adapted to change the resistant force provided by the motion limiting member when the regulating member is in direct engagement with the motion limiting member or constraining structure.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: March 12, 2013
    Assignee: Simpirica Spine, Inc.
    Inventors: Manish Kothari, Louis Fielding, Colin Cahill, Anand Parikh
  • Publication number: 20130053850
    Abstract: A device is formed by a discontinuous process into a bone screw, plate, or fastener, wherein the device has a degree of polymer alignment and strength, and upon reheating above glass transition temperature of the polymer, the device remains dimensionally stable, as it maintains its dimensions, strength, and degree of polymer orientation. In practice of the present invention, the polymer slug is pressed into the die cavity by the actuation of ram press, causing the slug to conform to the die cavity.
    Type: Application
    Filed: June 30, 2012
    Publication date: February 28, 2013
    Inventors: Joseph DeMeo, Patrick E. Heam, Robert L. McDade, Michael J. Popow
  • Patent number: 8288745
    Abstract: A novel method of partial breast radiation utilizing a breast implant which can provide a stable and improved target for stereotactic radiation treatment.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: October 16, 2012
    Assignee: Senorx, Inc.
    Inventors: John Corbitt, Lorl Anthony
  • Publication number: 20120226280
    Abstract: Methods of reducing device drag on implantable articles are disclosed herein. The methods include coating the contact surfaces of implantable articles with bioabsorbable lubricating coatings.
    Type: Application
    Filed: May 11, 2012
    Publication date: September 6, 2012
    Applicant: DEPUY MITEK, INC.
    Inventors: Mark B. Roller, Joseph H. Contiliano, Kevin L. Cooper, Jo Hays, Jenny J. Yuan
  • Patent number: 8197480
    Abstract: Bioabsorbable coatings for bioabsorbable implantable medical devices having dragging or engagement surfaces. The coatings on a surface of the devices reduce device drag.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: June 12, 2012
    Assignee: DePuy Mitek, Inc.
    Inventors: Mark B. Roller, Joseph Contiliano, Kevin L. Cooper, Jo Hays, Jenny J. Yuan
  • Patent number: 8075562
    Abstract: Controlled release of biopharmaceutical growth factors from a hydroxyapatite coating on a bioresorbable interference screw used in cruciate ligament reconstruction surgery on a human. Biologically active scaffolds, such as interference bone screws used for ligament fixation, made by growing calcium phosphate-based hydroxyapatite coatings on bioresorbable poly(?-hydroxy ester) scaffolds that provide controlled mineral dissolution and controlled release of bone morphogenetic protein-2. The biologically active scaffold provides improved bioavailability of BMP-2 growth factor that in turn provides enhanced graft-bone healing in the tibial bone tunnel. The coating method uses surface hydrolysis and modified simulated body fluid incubation which does not require solvent or heat and is conducted at room temperature.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: December 13, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: William L. Murphy, Jae-Sam Lee, Mark D. Markel, Ben K. Graf
  • Patent number: 8013107
    Abstract: The present invention provides a method of producing polyalkylene terephthalate, which comprises: introducing a prepolymer of polyalkylene terephthalate that is in a molten state comprising 70 mol % or more of ethylene terephthalate or 1,4-butylene terephthalate repeating units and having an intrinsic viscosity [?] between 0.2 and 2 dl/g through a feed opening to a polymerization reactor; discharging the introduced prepolymer from holes of a perforated plate; and polymerizing the prepolymer under reduced pressure, while allowing the prepolymer to fall along the surface of a support that is open towards the outside at a temperature between the [crystalline melting point?10° C.] of the prepolymer or higher and the [crystalline melting point+30° C.] of the prepolymer or lower under the conditions represented by a formula S1/S2>1, wherein S1 is the surface area of falling polyalkylene terephthalate, and S2 is the area where the support is in contact with polyalkylene terephthalate.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: September 6, 2011
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Hiroshi Yokoyama, Katsuhiro Fujimoto, Muneaki Aminaka, Junichi Sugimoto, Tsutomu Katsumata
  • Patent number: 8002843
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: August 23, 2011
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David Kaes, Todd Boyce, Lawrence A. Shimp
  • Patent number: 7979150
    Abstract: A method of manufacturing biodegradable/bioresorbable tissue augmentation/reconstruction devices by defining material density distributions at selected time points during a material degradation lifecycle. These different density distributions are then superposed using general linear and/or nonlinear functions that could include both time and degraded base stiffness weighting factors. The material density distribution may be created using topology optimization, image-based design or computed aided design methods to create a degradable device that retains sufficient physical properties (ie modulus, strength, electrical conductivity, thermal conductivity) through the material degradation lifecycle process. Thus, any bulk degrading material can be designed using this process for any tissue augmentation/reconstruction application.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: July 12, 2011
    Assignee: The Regents Of The University Of Michigan
    Inventors: Chia-Ying Lin, Scott J. Hollister
  • Patent number: 7914539
    Abstract: A fixation device for securing tissue to a bone. The fixation device includes an anchor having a hollow body defining a longitudinal passage, and a plug configured to be received in at least a portion of the passage. The body comprises a cylindrical portion and a tapered tip portion. The cylindrical portion comprises a plurality of thin-walled window covers such that after implantation the window covers are resorbed first relative to other portions of the cylindrical portion for defining a plurality of apertures on the cylindrical portion.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: March 29, 2011
    Assignee: Biomet Sports Medicine, LLC
    Inventors: Kevin T Stone, H. Gene Hawkins, Zachary M Hoffman, Gregory J Denham, Troy M Walters, Ryan A Kaiser, Jason D Meridew
  • Patent number: 7910134
    Abstract: A composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent is provided. A method of making a composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent, said method comprising admixing a biocompatible and pliable material with a physiologically acceptable suspending agent, is also provided. A method of augmenting soft tissue to provide long-term reduction of a skin defect, said method comprising stimulating collagen beneath the skin defect is further provided.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: March 22, 2011
    Inventor: Ayman Boutros
  • Patent number: 7875063
    Abstract: A method for fabricating a device for repairing torn tissue or muscle such as the meniscus of the knee. The device includes a pair of anchoring members having a plurality of barb-like projections extending outwardly therefrom. The anchoring members are joined by a flexible linking member which connects the ends of the anchoring members opposite one another. Such a device can be fabricated by insert molding of the appropriate members together.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: January 25, 2011
    Assignee: Tyco Healthcare Group LP
    Inventors: Thomas W. Sander, Daniel R. Lee, Wayne C Person, Steven Howansky
  • Patent number: 7850717
    Abstract: A bone anchor including a bone engaging element and an implant engaging element. The bone engaging element includes a first portion formed of a first material and a second portion formed of a second material and extending at least partially along a length of the first portion, and with the second portion of the bone engaging element positioned between the first portion and adjacent bone tissue when the bone engaging element is engaged with the bone to provide an interface with the adjacent bone tissue. In one embodiment, the first portion of the bone engaging element exhibits a first level of rigidity and the second portion exhibits a second level of rigidity less than the first level of rigidity. In another embodiment, the bone engaging element includes external threads, with the second portion of the bone engaging element defining at least a portion of the external threads.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: December 14, 2010
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Jonathan Dewey, Chris Patterson
  • Patent number: 7838122
    Abstract: Compounds exhibiting angiogenic properties incorporating the structure of Formula I: R3—NH—NH—C(?O)—R2—P—R1??(I) wherein P is a water-soluble, biodegradable polymer, R1 is hydrogen, lower alkyl, lower alkoxy or —R2—C(?O)—NH—NH—R3; each R2 is independently —CH2—, —NH— or O; and each R3 is independently hydrogen or a residue of a naturally occurring alpha-L-amino acid or dipeptide thereof. Polymer networks crosslinked with hydrazide compounds are also disclosed, together with implantable medical devices incorporating the compounds and crosslinked polymers, and angiogenesis-promoting treatment methods, including wound-treatment methods.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: November 23, 2010
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Joachim B. Kohn, Kristen S. Labazzo, Durgadas Bolikal
  • Patent number: 7824434
    Abstract: Disclosed is a fastener that can be mounted to a bone of a patient and can foreshorten and swell of a desired period of time. The fastener can include a head portion and a body portion extending from the head portion. At least one of the head portion and the body portion has a first width that changes to a second width greater than the first width and collectively the head portion and the body portion have a first length that changes to a second length shorter than the first length upon the head portion and the body portion being exposed to a temperature below a glass transition temperature of a polymeric material forming the head portion and the body portion.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: November 2, 2010
    Assignee: DEGIMA GmbH
    Inventor: Randolf von Oepen
  • Patent number: 7819906
    Abstract: A surgical rivet device for the repair of torn menisci and other intra-articular bodily tissues is disclosed in which the device comprises a shaft, projecting fins and a penetration head at one end and a wide rear portion. The device is inserted by a driving mechanism through both sides of the torn meniscus, compressing the tear in the meniscus between the fins near the head and the wide rear portion, holding the tear together. After insertion, the driving mechanism is separated from the rivet, leaving the rivet device in the patient. The rivet device is entirely biodegradable and absorabable by the body.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: October 26, 2010
    Inventor: Gary Karlin Michelson
  • Patent number: 7796791
    Abstract: The present invention relates to methods for determining meniscal size and shape for use in designing therapies for the treatment of various joint diseases. The invention uses an image of a joint that is processed for analysis. Analysis can include, for example, generating a thickness map, a cartilage curve, or a point cloud. This information is used to determine the extent of the cartilage defect or damage and to design an appropriate therapy, including, for example, an implant. Adjustments to the designed therapy are made to account for the materials used.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: September 14, 2010
    Assignee: ConforMIS, Inc.
    Inventors: Konstantinos Tsougarakis, Daniel Steines, Bhaskar Rao Vissa, Philipp Lang, Barry J. Linder
  • Publication number: 20100185199
    Abstract: Bioabsorbable coatings for bioabsorbable implantable medical devices having dragging or engagement surfaces. The coatings on a surface of the devices reduce device drag.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Applicant: DEPUY MITEK, INC.
    Inventors: Mark B. Roller, Joseph H. Contiliano, Kevin L. Cooper, Jo Hays, Jenny J. Yuan
  • Patent number: 7713272
    Abstract: Bioabsorbable coatings for bioabsorbable implantable medical devices having dragging or engagement surfaces. The coatings on a surface of the devices reduce device drag.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: May 11, 2010
    Assignee: Ethicon, Inc.
    Inventors: Mark B. Roller, Joseph H. Contiliano, Kevin L. Cooper, Jo Hays, Jenny J. Yuan
  • Publication number: 20090306725
    Abstract: A magnesium-based medical device which can adjust a degree of corrosion within a wide range of period such that the device can maintain a sufficient strength only during a desired period and disappears within a desired period thereafter and a manufacturing method thereof are provided. A magnesium-based medical device of the present invention is a magnesium-based medical device in which a base material is made of magnesium or a magnesium alloy, wherein a corrosion-resistant film is formed on a surface of the base material, and variation in surface hardness of the formed corrosion-resistant film in the in-plane direction is less than 21 in terms of a dispersion value of Vickers hardness.
    Type: Application
    Filed: November 16, 2007
    Publication date: December 10, 2009
    Inventors: Sachiko Hiromoto, Akiko Yamamoto, Norio Maruyama, Toshiji Mukai, Hidetoshi Somekawa
  • Patent number: 7588594
    Abstract: A method for fabricating a device for repairing torn tissue or muscle such as the meniscus of the knee. The device includes a pair of anchoring members having a plurality of barb-like projections extending outwardly therefrom. The anchoring members are joined by a flexible linking member which connects the ends of the anchoring members opposite one another. Such a device can be fabricated by insert molding of the appropriate members together.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: September 15, 2009
    Inventors: Thomas W. Sander, Daniel R. Lee, Wayne C Person, Steven Howansky
  • Patent number: 7572298
    Abstract: An implantable medical device is disclosed. The device is fabricated at least in part from a biocompatible, biodegradable composition. The composition is composed of a biocompatible, biodegradable polymer and a biocompatible, biodegradable wax. The concentration of the wax at the surface of the device is greater than the concentration of the wax in the body of the implantable device. The increased concentration of wax at the device surface may be attained when the device is heated to a temperature greater than the melting point of the wax and the glass transition temperature of the polymer, but lower than melting point of the polymer.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: August 11, 2009
    Assignee: Ethicon, Inc.
    Inventors: Mark B. Roller, Yufu Li, Jenny J. Yuan
  • Publication number: 20080255561
    Abstract: A medical device for surgical applications including a body. The body includes bioabsorbable basic material and has a longitudinal axis. The body includes an inner region and a peripheral region transverse to the longitudinal axis so that the peripheral region surrounds the inner region. The inner region is made of bioabsorbable basic material and the peripheral region includes the bioabsorbable basic material. The peripheral region includes a bioabsorbable reinforcing structure in addition to the bioabsorbable basic material.
    Type: Application
    Filed: April 14, 2008
    Publication date: October 16, 2008
    Applicant: BIORETEC OY
    Inventors: Pertti Tormala, Mikko Huttunen, Harri Heino
  • Publication number: 20080228187
    Abstract: A device is formed by the process into a bone screw or fastener, wherein the head has a degree of polymer alignment and strength, and wherein the shank has a higher degree of polymer alignment and strength. In practice of the present invention, the polymer slug is pressed into the die cavity by the actuation of ram press, causing the slug to conform to the die cavity. Through this process, the polymer molecular orientation is aligned to different degrees, in different zones of the device.
    Type: Application
    Filed: May 13, 2008
    Publication date: September 18, 2008
    Inventors: Joseph DeMeo, Patrick E. Heam, Robert L. McOade
  • Publication number: 20080221594
    Abstract: A method and apparatus for repairing a bone defect in a cranium includes a frame defining a plurality of openings. The frame may be adapted to generally span the bone defect in an implanted position. Bone-growth promoting material may generally overlap the openings and secured to the frame to cover at least some of the respective plurality of openings. At least one stabilizing member may be attached to the frame for stabilizing the apparatus relative to the cranium.
    Type: Application
    Filed: January 29, 2007
    Publication date: September 11, 2008
    Inventors: Ned M. Hamman, David A. Werntz