Abstract: A method of treatment of skin tissue with two laser devices of unequal wavelengths comprising the steps of: (1) activating the two laser devices simultaneously to produce two laser beams of unequal wavelength; (2) directing the two laser beams into a handpiece having a distal tip to direct the laser beams onto the skin tissue; (3) directing the two laser beams within the handpiece to an adjustable beam deflector; and, (4) the adjustable beam deflector directing the two laser beams onto the skin tissue to produce a pattern of laser spots simultaneously but separated from one another.

Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.

Abstract: The present disclosure provides apparatuses and computer readable media for measuring sub-epidermal moisture in patients to determine damaged tissue for clinical intervention. The present disclosure also provides methods for determining damaged tissue.

Abstract: A computerized method for controlling the operation of a laser therapy device is disclosed. A laser therapy device comprising laser diodes has a microprocessor for storing and executing instructions pertaining to the operation of the laser diodes within certain parameters. The computerized method detects the movement of the laser therapy device and alters the output of the laser diodes when a movement signal exceeds predetermined threshold parameters. The computerized method detects difference in temperature in certain areas, and patterns in temperature differences, for assistance in diagnosing ailments. The computerized method also detects differences in skin color to determine treatment areas. The computerized method also measures the distance of the laser therapy device to a treatment area. The microprocessor executes instructions then which can alter the output of the laser diodes or generate an alarm signal based on measurements received.

Abstract: According to the invention, there is provided a light-based skin treatment device comprising a treatment light source; a treatment light exit window via which, during operation, treatment light generated by the treatment light source is applied to skin of a user, wherein the treatment light exit window comprises an optically transparent material arranged to contact the skin during operation; and an imaging unit comprising an image sensor 5 arranged to generate an image of the skin during operation.

Abstract: The disclosed invention relates to an improved system and method for treatment of soft tissue, e.g., for treatment of a snoring condition. The system can include a laser source; a hand piece; and a device for directing radiation emitted by the laser source to a treatment area (e.g., an oral treatment area). In some cases, the handpiece can include an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam such that it is non-ablative, prior to its delivery to a treatment region. In various embodiments, the system includes a CO2 laser capable of performing treatment in a more efficient manner than conventional techniques.

Abstract: A method of treating a skin tissue area, in particular non-invasively treating the skin tissue area (1), is provided. The skin tissue area has a dermis layer area (3), an epidermis layer area (5) providing a skin surface (7) and covering the dermis layer area. The method comprises: a first step of causing one or more dermal lesions (11) localized in the dermis layer area while avoiding epidermal damage, and a second step of causing, separately from causing said plurality of dermal lesions, a plurality of epidermal lesions (15) localized in the epidermis layer area. An apparatus is also provided.

Abstract: Disclosed are a microbe inactivation processing method that can perform inactivation processing of microbes, while damage to human body cells is prevented or inhibited, with an efficient use of light emitted from a light source and the obtainment of a large effective irradiation area. Also provided are a cell activation processing method that can reliably activate target cells with high efficiency. The microbe inactivation processing method includes: a step of applying light emitted from a light source through an optical filter, with the light source configured to emit light having a wavelength within a wavelength range of 190 nm to 237 nm, in order to perform inactivation processing of a target microbe.

Abstract: In an embodiment a sensor device includes a first optoelectronic emitter configured to irradiate a spot with electromagnetic rays, a second optoelectronic emitter configured to irradiate the spot with electromagnetic rays, a detector configured to detect electromagnetic rays from the first and second emitters reflected at or transmitted through the spot, wherein the electromagnetic rays of the first emitter have a wavelength in a range of 1400-1500 nm, wherein the electromagnetic rays of the second emitter have a wavelength in a range of 900-1100 nm, and wherein the second emitter is configured to emit at least one further electromagnetic signal, the one further electromagnetic signal not being used for measuring a humidity.

Abstract: Technologies are generally described for normalized standard deviation transition based dosimetry monitoring for laser treatment. In some examples, a response signal may be generated based on a physical response to a laser pulse detected through acoustic or optical means. Each response signal may be a time series of data with a number of points. Standard deviation may be determined for each response signal and normalized using a mean or comparable normalization factor. Thus, a robust distribution may be computed from the response to each laser pulse. A change in the normalized standard deviation from each single pulse's time domain response data may be used to determine how many laser pulses remain before completion of the treatment (similar to event onset response). Thus, laser treatment may be continued based on an estimation of remaining pulses for completion or ceased if completion is reached.

Abstract: A hair cutting device for cutting hair on a body of a subject includes a light source for generating laser light at one or more specific wavelengths corresponding to wavelengths absorbed by one or more chromophores in hair; and a cutting element that has an optical waveguide that is coupled to the light source to receive laser light. A portion of a side wall of the optical waveguide forms a cutting face for contacting hair where, at least at the cutting face, the optical waveguide has a refractive index that is equal to or lower than the refractive index of hair and higher than the refractive index of skin.

Abstract: The illustrated embodiments include an apparatus to reduce or eliminate full thickness injury in tissue and to deform tissue which includes a probe or mechanism for deforming tissue, and a subsystem for selectively cooling and/or heating tissue while deformation is of the tissue is being performed. The illustrated embodiments of the invention also extend to a method to reduce or eliminate full thickness injury in tissue and to deform tissue including the steps of deforming tissue, and selectively cooling and/or heating tissue while deformation of the tissue is being performed.

Abstract: A device and a method for stimulating skin regeneration is described which allows exploiting the combined action of the surface vasculature (given by the action of the vacuum) and of the cellular regeneration (given by the electromagnetic field generated by a capacitive system) combined with the skin electrostimulation applied, in this case, so as to amplify the biological effect of the electromagnetic field.

Abstract: A lighting apparatus including a controller including a real time clock, an LED driver, and an LED luminaire including a first light emitting unit including a first LED to emit light having a peak wavelength between 300 to 470 nm and a wavelength converter, and at least one of a second light emitting unit to emit light having a peak wavelength between 286 to 304 nm to cause production of vitamin D, a third light emitting unit to emit light having a peak wavelength between 605 to 935 nm to cause production of a cell activating substance, and a fourth light emitting unit to emit light having a peak wavelength between 400 to 430 nm to sterilize pathogenic microorganisms, in which the controller controls the LED driver to change an irradiance of light emitted from at least one of the light emitting units according to time.

Abstract: A pulsed laser skin treatment device is for laser induced optical breakdown of hair or skin tissue. A beam scanning system scans the beam to define a circular or arc path, using a rotated prism which implements a lateral shift to the beam. A focusing system at the output side of the beam scanning system focuses the incident light beam into a focal spot in the hair or skin tissue, and it rotates with the prism.

Abstract: The present invention relates to an apparatus for treating skin by means of intense pulsed light (IPL). Such apparatus may be used for the treatment of, for example, cosmetic purposes such as hair depilation or dermatological treatment of skin conditions such as acne or rosacea. The present invention provides an improved apparatus that can be used by a non-medical practitioner and comprises a light source comprising a light emitting element for transmitting light energy to the skin and a charge storage device for discharging an energy dose to the light emitting element. There is further provided at least one sensor for measuring a parameter of the skin and a control system configured to determine the treatment energy dose to be delivered. This treatment energy dose is de-rived using the sensor measurement and means of reduction in unwanted time delay associated with charging or discharging of the charge storage device in sole dependence on the current or most recently measured skin parameter.

Abstract: The present invention relates to a cutter assembly (10) for a hair cutting appliance (100). The cutter assembly comprises a cutting element (20), and a clamping element (30). The cutter assembly is configured to contact skin of a user of the hair cutting appliance. The clamping element is configured to clamp hair of the user that is growing out of the skin. The clamping element is configured to move within the cutter assembly to pull the clamped hair away from the skin of the user. The cutting element is configured to cut the clamped hair that has been pulled away from the skin of the user.

Abstract: A method for determining a suitable set of parameters for operating a light source within a photo-thermal targeted treatment system for targeting a chromophore embedded in a medium is disclosed. The method includes, before administration of a treatment protocol: 1) administering at least one laser pulse from the light source at a preset power level to a location to be treated, the preset power level being below a known damage threshold; 2) measuring a skin surface temperature at the location to be treated, following administration of the at least one laser pulse; 3) estimating a relationship between the parameters for operating the light source and the skin surface temperature; and 4) defining a safe operating range for the parameters for operating the light source in order to avoid thermal damage to the medium at the location to be treated while still effectively targeting the chromophore in administering the treatment protocol.

Abstract: A needle tip mounted on a skin care device and the skin care device are provided to prevent a proximity effect. The needle tip includes a case, a holder disposed in the case and reciprocating in a vertical direction, and a plurality of needle electrodes disposed in the holder, a current being applied to the plurality of needle electrodes. The plurality of needle electrodes include a first group of needle electrodes and a second group of needle electrodes to which the current is applied at mutually different times.

Abstract: A non-invasive, optical method and device for the detection of melanoma in skin lesions. The detection of the presence of melanoma is accomplished optically by looking for specific changes (signatures) in the spectrum of optical light elastically scattered off melanoma molecules. Elastic scattering spectroscopy (ESS) converts subcellular morphological changes into scattering spectrum signatures. A melanoma discrimination analysis is performed by illuminating the lesion with a handheld device that also collects a portion of the scattered light, converts it into digital signals, analyzes the requisite spectral signatures, and provides a logical output showing the user the presence (or absence) of melanoma in the subject lesion.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: In one aspect, devices for light treatment of skin are described herein. A device described herein, in some embodiments, comprises an interior compartment having a proximal end and a distal end, and an optical aperture disposed at the distal end. The device also comprises a laser or BBL source that produces a laser or BBL beam. The laser or BBL beam has a first optical path within the interior compartment, between the proximal end and the distal end. Additionally, the first optical path exits the interior compartment through the optical aperture. The device further comprises a camera that receives light from the aperture. The light received from the aperture has a second optical path within the interior compartment. Further, a selectively reflective optical element is disposed in the first and second optical paths. The selectively reflective optical element generally transmits the laser or BBL beam but generally reflects at least a portion of the light from the aperture toward the camera.

Abstract: In one aspect, devices for light treatment of skin are described herein. A device described herein, in some embodiments, comprises an interior compartment having a proximal end and a distal end, and an optical aperture disposed at the distal end. The device also comprises a laser or BBL source that produces a laser or BBL beam. The laser or BBL beam has a first optical path within the interior compartment, between the proximal end and the distal end. Additionally, the first optical path exits the interior compartment through the optical aperture. The device further comprises an imaging system that receives a return signal from the aperture. The return signal received from the aperture has a second path within the interior compartment. Further, a selectively reflective optical element is disposed in the first and second optical paths. The selectively reflective optical element generally transmits the laser or BBL beam.

Abstract: A system for capturing, storing and comparing dermatological images includes two components, namely, a handheld exam control and a patient interface. The handheld exam control includes a camera, display screen, illuminator and a position sensor. The patient interface includes a patient position template and a position sensor interface. The system captures an image sequence and the precise location of each image. Images may be compared to previous images by a clinician.

Abstract: An apparatus is provided for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's Disease, Alzheimer's Disease, or depression. The apparatus includes a source of the electromagnetic radiation. The apparatus further includes an output optical element including a rigid and substantially thermally conductive material and a surface configured to be in thermal communication with the patient's body. The apparatus further includes a cooler thermally coupled to the output optical element to remove heat from the output optical element. The apparatus further includes a heat sink thermally coupled to the cooler, wherein the heat sink is positioned so that the electromagnetic radiation from the source propagates through the heat sink and through the output optical element.

Abstract: An exemplary treatment system can be provided which can include a laser system configured to emit at least one laser beam, and an optical system configured to focus the laser beam(s) to a focal region at a selected distance from a surface of a tissue. The focal region can be configured to illuminate at least a portion of a target. The optical system can cause an irradiation energy transferred to the focal region of the laser beam(s) to (i) generate a plasma in a first region of the tissue adjacent to the target, and (ii) avoid a generation of a plasma in a second region of the tissue. The optical system has a numerical aperture that is in the range of about 0.5 to about 0.9. An exemplary method can also be provided to control such treatment system.

Abstract: A control method for a light therapy device, including steps of: set a light dose range (1-4J/cm2) required by an illuminated portion under a skin surface; calculate an appropriate intensity range outputted by a light source based on the set light dose, an illuminated time, and a proportion of light beam shape variation between the light source and the skin surface; build a corresponding relation between the appropriate intensity range and an ideal illumination range for the skin surface; measure an illumination of the skin surface, and monitor an output light intensity of the light source based on the illumination, ensuring that a light intensity outputted by the light source is a set ideal light intensity whereby, a light dose transmitted from the light therapy device to the illuminated portion could be kept in the set light dose by simply controlling the illumination to be within the set illumination range.

Abstract: The invention resides in a pattern laser comprising a plurality of laser devices each emitting a treatment laser beam into an optical fibre of an optical fibre bundle. An optical coupling module is associated with each laser device and each optical fibre for coupling a treatment laser beam into the associated optical fibre. A controller controls the operation of the laser devices by selectively turning on or off one or more of the laser devices so as to form a laser treatment pattern at an end of the fibre bundle away from the laser devices. A delivery system images the output from the fibre bundle to a treatment zone.

Abstract: A method for providing localized heating of the dermal layers of skin of a patient, using energy in the form of a group of pulses having defined parameters in a controlled manner. This method preferably uses an optical delivery system to deliver pulsed energy to a specific spot of skin so that targeted layers of the affected skin are heated to a desired temperature range. The temperature range is optimally selected to maximize treatment efficacy while minimizing pain to the patient. Example applications include reducing wrinkles, acne, hair, scar tissue, warts, and promoting wound healing. In this method, the temperature of the selected locus rises quickly to the desired temperature range, then is maintained within a controlled range with a relatively flat temperature profile. The method maintains the temperature by controlling one or more of a pulse energy intensity, pulse width, and pulse frequency or time delay between pulses.

Abstract: A method for treating an eye, including the step of applying an electromagnetic wave of distorted sinusoidal current with a resonance frequency and having related harmonics on an eye, an eye orbit, a temple, eyelid areas or a part thereof.

Abstract: A personal care system having a treatment device for applying a treatment to the skin or hair of a user is provided. The treatment device has a camera for taking an image of the skin. The system may include or be in communication with an application programming interface (API) that can process the image. The system or an associated API can recommend the use of treatment regimens or topical products according to information determined from the digital image of the skin.

Abstract: The present invention relates to a light treatment apparatus and a method of controlling the same, and provides to a light treatment apparatus and a method of controlling the same, including: a treatment light irradiating unit for irradiating a treatment region with treatment light a plurality of times while moving on the treatment region; a sensing unit for detecting movement information of the treatment light irradiating unit; and a control unit for controlling an irradiation pattern of the treatment light based on the detected movement information such that an irradiation area of the treatment light to be irradiated from the treatment light irradiating unit overlaps at least in part with an irradiation area of the treatment light which is previously irradiated.

Abstract: A method of producing an array of sharp tips including a biocompatible coating, wherein the biocompatible coating is thicker at a sharp end of the sharp tips than at a broader section of the sharp tips, the method including providing an array of sharp tips, and coating the sharp end of the sharp tips differentially from coating the broader section of the sharp tips. A method of treating skin including producing a hollow in the skin by heating and mechanically compressing epidermis while retaining a covering of stratum corneum. A method of treating tissue including heating a tip to a temperature suitable for producing a crater in the tissue, advancing the tip toward the tissue, detecting when the tip comes into contact with the tissue by detecting a change in mechanical resistance to the advancing, and measuring the mechanical resistance to the advancing. Related apparatus and methods are also described.

Abstract: A process for heat treating biological tissue includes providing a plurality of energy emitters formed into an array. Treatment energy is generated from the plurality of emitters and applied to target tissue. The treatment energy has energy and application parameters selected so as to raise the target tissue temperature sufficiently to create a therapeutic effect while maintaining an average temperature of the target tissue over several minutes at or below a predetermined temperature so as not to destroy or permanently damage the target tissue.

Abstract: Exemplary methods and devices can be provided for improving the appearance of dermal melasma. This can be done, e.g., focusing electromagnetic radiation having a wavelength between about 600 nm and 850 nm into a region of the pigmented dermal tissue at a depth between about 150 and 400 microns, using a lens arrangement having a large numerical aperture between about 0.5 and 0.9. The exemplary local dwell time of the focused radiation can be less than a few milliseconds, and a local fluence provided in the focal region can be between about 50 and 500 J/cm2. The focal region can be scanned through the dermal tissue at speeds on the order of a few cm/s. Such parameters can provide sufficient energy absorption by pigmented cells in the dermis to disrupt them while avoiding damage to the overlying tissue and unpigmented dermal tissue.

Abstract: A mouth guard comprising a plurality of light sources is presented that provide for the emission of light in wavelength ranges that provide antiseptic benefits to a user, wherein the light outputted by the plurality of light sources are activated by a sensor configured to determine a proximity of the mouth guard to an object and generate a signal that is used to control the application of a voltage to the plurality of light sources, for a predetermined time period.

Abstract: A pulsed laser skin treatment device is for laser induced optical breakdown of hair or skin tissue. A feedback system is used for detecting a feedback system based on light and/or sound/and/or contact force or pressure. The feedback signal is used to determine whether a pulse was in the tissue or outside the tissue. With these data an effectiveness of the treatment can be determined which can be provided to a user.

Abstract: Exemplary methods and devices can be provided for improving the appearance of dermal melasma. This can be done, e.g., focusing electromagnetic radiation having a wavelength between about 600 nm and 850 nm into a region of the pigmented dermal tissue at a depth between about 150 and 400 microns, using a lens arrangement having a large numerical aperture between about 0.5 and 0.9. The exemplary local dwell time of the focused radiation can be less than a few milliseconds, and a local fluence provided in the focal region can be between about 50 and 500 J/cm2. The focal region can be scanned through the dermal tissue at speeds on the order of a few cm/s. Such parameters can provide sufficient energy absorption by pigmented cells in the dermis to disrupt them while avoiding damage to the overlying tissue and unpigmented dermal tissue.

Abstract: Provided herein is a multifunctional aesthetic system including a housing, an electromagnetic array situated in the housing and having a plurality of electromagnetic radiation (EMR) sources, each EMR source configured to generate an EMR beam having a wavelength different than that of an EMR beam generated by another of the EMR sources, a controller in electronic communication with the array to operate two or more of the EMR sources to direct the EMR beam to a treatment area, and a sensor in electronic communication with the controller for providing feedback to the controller based on defined parameters to allow the controller to adjust at least one operating condition of the multifunctional system in response to the feedback.

Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. The target is irradiated with pulsed purple or blue light in which (a) the light pulses have a peak irradiance and a pulse duration sufficient to optically excite a photoactive molecule capable of photoeradication of the microorganisms and (b) the light pulses are separated by an off time sufficient to allow the photoactive molecule to return to a ground state creating an oxidation reaction that produces free radicals which destroy a cellular structure of the microorganisms and thereby photoeradicate all or a portion of the microorganisms. The photoactive molecule may comprise either an endogenous molecule present in the microorganisms or an exogenous molecule applied to the target.

Abstract: Systems, methods, and devices for promoting eyelash hair growth includes an energy transducer, positionable proximate the eyelid, configured to provide light energy to a user's eyelids at an output wavelength suitable for stimulating eyelash hair growth, and a scleral shield, positionable inside of the eyelid, to protect the eye from the light energy. The device may be powered by an internal power source, such as a rechargeable battery or disposable batteries, or by an external power source, such as a plug used in connection with an AC outlet. In use, the eyelid is positioned between the energy transducer and the scleral shield, and the light energy from the energy transducer is applied to the eyelash region of the eyelid to promote eyelash hair growth.

Abstract: A device configured to cut hair using laser light includes a handle portion and a shaving portion. The handle portion includes a battery and a laser light source. The laser light source is coupled to and configured to receive power from the battery. The laser light source is also configured to generate laser light having a wavelength selected to target a predetermined chromophore to effectively cut a hair shaft. The shaving portion includes a support and a single fiber optic supported by the support. The fiber optic has a proximal end, a distal end, an outer wall, and a cutting region positioned towards the distal end and extending along a portion of the side wall. The fiber optic is positioned to receive the laser light from the laser light source at the proximal end, conduct the laser light from the proximal end toward the distal end, and emit the light out of the cutting region and toward hair when the cutting region is brought in contact with the hair.

Abstract: A laser device for the selective treatment of acne comprising: a laser source (1) terminating in an optical collimator (2), which supplies a laser beam; said laser source (1) comprises a switch (13) which allows impulses of said laser beam with pre-defined duration to be transmitted; an opto-mechanical interface (3) comprising a lens (4) focusing the laser beam received from the optical collimator (2); an optical fibre (5) connected to said opto-mechanical interface (3); characterized in that said optical fibre (5) has a length greater than 15 m; and said device comprises a handpiece (10) connected to said optical fibre (5) where said handpiece (10) comprises an optical zoom system (11) which allows the diameter of the laser beam emerging from said handpiece (10) to be varied from 0.5 mm to 5 mm.

Abstract: In accordance with various aspects of the present teachings, systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation in the visible and near infrared wavelengths, to body areas having bulges and fat deposits, loose skin, pain, acne and/or wounds. In some aspects, the systems and methods can enable relatively lengthy treatments to be performed by having the practitioner set-up and/or start the treatment, thereafter allowing the treatment to proceed safely and effectively without the continued presence of the practitioner.

Abstract: Various embodiments provide a method for an extended field of view treatment. The method can include the steps of imaging a region; targeting a region with directed ultrasound energy; monitoring the region; moving the imaging, treatment, and monitoring region while spatially correlating to one or more prior regions via imaging and/or position sensing; continuing the extended field of view treatment; and, achieving an ultrasound induced biological effect in the extended field of view treatment region.

Abstract: A lipolysis radiation paddle (2) comprises a plurality of lipolysis radiation transducers (14) mounted in a base (20). The base (20) has a lower portion (21), and a pair of side portions (26) extending upwardly from respective sides of the lower portion (21). The lower portion (21) is shaped to fit under the jaw (51) of a user (50) of the paddle (2), and has a front end (22) shaped to receive the chin (52) of the user (50). The side portions (26) are each shaped to extend to and along respective sides of the jawline (53) of the user (50). The transducers (14) are directed inwardly towards the skin in proximity to the paddle (2).

Abstract: A therapy apparatus for treating a patient's brain is provided. The therapy apparatus includes a light source having an output emission area positioned to irradiate a portion of the brain with an efficacious power density and wavelength of light. The therapy apparatus further includes an element interposed between the light source and the patient's scalp. The element is adapted to inhibit temperature increases at the scalp caused by the light.

Abstract: Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Abstract: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.

Abstract: Provided are a morbidity diagnosis support system, a morbidity diagnosis data-generating system, and a morbidity diagnosis support method that are capable of supporting a highly reliable morbidity diagnosis. A morbidity diagnosis support system includes an extension device for extending a tissue section of cells, an image-photographing device for acquiring image data by image-photographing the tissue section, an image analysis device for analyzing the image data to calculate an index of morbidity based on a mode of cracks generated in the tissue section by the extension, and an output device for outputting the calculated index.