Abstract: A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).

Abstract: An apparatus for selective heating of a biological tissue comprising a plurality of gapped toroidal solenoids having a common gap area to provide a sum of magnetic fields created by the solenoids in common localization. Each solenoid comprises a toroidally configured magnetic core and an electric coil thereupon. The coil is connectable to a generator of electric pulses. The solenoid plurality is accommodated within a housing having an opening configured for emitting solenoid electromagnetic radiation.

Abstract: A treatment device using a high frequency according to the present invention includes: a plurality of electrodes which transfers high frequency energy to the skin; a plurality of pads each of which is provided on one surface thereof with at least one of the electrodes; and a plurality of elastic members which independently and elastically support the other surfaces of the plurality of pads, respectively, so that plurality of electrodes can be three-dimensionally and closely attached to the curved surface of the skin. Accordingly, even when treating a body region having many curves, the attachment of the electrodes is efficiently maintained. In addition, although a hand piece moves in a state in which the plurality of pads are attached to skin, the plurality of pads can be maintained in the skin attached state while actively coping with the curves.

Abstract: A resonant radio frequency diathermy heat applicator, including a flexible pad, an inductive coil with moderate defined resistance, fixed tuning capacitors, connecting cable and shielding that is broadly tuned to the signal source in a manner that eliminates the requirement for variable tuning elements.

Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.

Abstract: Medical implants can comprise various instrumentation to impart desirable functionality to the implant. In some embodiments, the implants comprise functional structures, such as sensors, energy propagating transducers, drug delivery systems and the like. Additional instrumentation to facilitate the functionality of these devices can include, for example, microprocessors, communication systems, power sources or the like. Drug delivery systems can comprise, for example, an isolated reservoir with a control system to control the delivery of a biological agent from the reservoir. The implants can be orthopedic implants that are designed to interface with a patient's skeletal system wherein the orthopedic implant may itself embody sensors, processors, power supplies, memory and/or communication capability.

Abstract: A device for treating a tissue region at or near a sphincter including a proximal support, a distal support and an expandable basket having a plurality of spines. The spines have a proximal portion, a distal portion and an intermediate portion therebetween, wherein the spines are movable from a first non-expanded position to a second expanded position wherein in the expanded position the intermediate portion of the spines extends outwardly radially beyond the proximal and distal portions of the spines. A plurality of electrodes are carried by the spines and movable outwardly to an outward position to penetrate tissue for application of energy to the tissue region.

Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for extravascular delivery of pulsed electric fields to achieve such neuromodulation.

Abstract: The invention relates to a hyperthermia system for treating a patient, comprising an RF power unit, one or more RF antenna's connected to the RF power unit for generating a focused three-dimensional RF field, a controller for adjusting the RF power source and/or the one or more RF antenna's for steering the focused three-dimensional RF field; a sensor for sensing a parameter representative of the focused three-dimensional RF field; a communication environment for inputting data from the said sensor and/or additional information provided by the patient, said communication environment being capable of generating trigger signals to the controller for in use steering the focused three-dimensional RF filed in real time. The invention further relates to a method for generation a focused three-dimensional RF field.

Abstract: A novel medical probe assembly, system, and methods for the use thereof to treat tissue are described. The system optionally comprises an energy source, two probe assemblies, and one or more cooling devices to provide cooling to at least one of the probe assemblies. The probe assemblies may be configured in a bipolar mode, whereby current flows preferentially between the probe assemblies. The probe assemblies and system described herein are particularly useful to deliver radio frequency energy to a patient's body. RF energy delivery may be used for various applications, including the treatment of pain, tumor ablation and cardiac ablation.

Abstract: The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.

Abstract: A method and apparatus for treating an intraosseous nerve. The method includes positioning a hollow shaft through the cortical shell of a vertebral body and into a cancellous bone region of the vertebral body. The hollow shaft includes an annular wall having a longitudinal bore therein, a proximal portion and a distal portion, and a first window extending transversely through the annular wall. An electrosurgical probe is advanced within the longitudinal bore from the proximal portion toward the distal portion. The electrosurgical probe includes a first treatment element at a distal end of the probe, wherein the first treatment element being in electrical connection with a power supply. The first treatment element is slidably disposed within the longitudinal bore so that the first treatment element is advanced radially outward from the window and shaft to affect treatment of the intraosseous nerve within the cancellous bone region.

Abstract: The portable, wearable, proximal Alzheimer's disease treatment invention is based upon creating an RF field of particular frequencies and intensities that are applied to the patient's head. To accomplish the aforementioned disease treatment functionality, a system was invented comprising a network of antennas connected to an RF generator via a feedline connector. The invention also provides methods for using measurements to monitor and manage the effectiveness of an ongoing disease treatment regimen, and databases which contain information about measurements, variables, and their relationships to clinical outcome.

Abstract: Non-invasive and/or natural orifice procedures, apparatus and methods for modulating the enteric nervous system using one or more energy modalities. A system may include a probe for insertion into a natural orifice (e.g., nasogastrically, orogastrically, nasojejunally) with or without a tube to therapeutically apply energy to modulate one or more portions of the enteric nervous system. The methods described herein may provide energy to stimulate the enteric nervous system to treat disorders such as irritable bowel syndrome, constipation, depression, anxiety and/or to enhance gastric motility, intestinal motility or other neurological responses.

Abstract: A magnetically-guided catheter 100 includes a tip positioning magnet in the distal electrode assembly configured to interact with externally applied magnetic fields for magnetically-guided movement. A magnetically-guided mapping catheter 100 includes an electrically-conductive capsule in the form of a casing 146 that includes a distal ablation surface and isolates the positioning magnet from bio-fluids to prevent corrosion. An open irrigation ablation catheter includes an isolated manifold that isolates the positioning magnet from contact with irrigation fluid to prevent corrosion.

Abstract: The microwave antenna assembly includes a feedline electrically connected to an elongated shaft by a choke electrical connector. The feedline includes an inner conductor, an outer conductor, an elongated shaft and a choke electrical connector. The inner conductor is disposed in coaxial arrangement with the inner conductor and forms a dielectric supply lumen therebetween. The elongated shaft at least partially surrounding the feedline and form a dielectric return lumen therebetween. The choke electrical connector surrounds at least a portion of the feedline and electrically connects the feedline outer conductor to the elongated shaft. A low-loss dielectric fluid is supplied between the inner conductor and the outer conductor of the feedline and forms a dielectric barrier therebetween.

Abstract: Hair or partial hair removal system and hair growth deterrent that includes mechanical process for cutting, plucking or shaving hair follicles, along with pre and/or post skin treatment techniques. The skin treatment techniques can include the application of energy to the skin surface before, after and/or during the application of the mechanical process. Such techniques include the application of heat and/or energy from illumination sources and/or RF emitters. Further skin treatment techniques include the application of solutions before, after and/or during the mechanical process and/or the application of heat and/or energy. Overall, the system operates to treat an area of skin to facilitate the removal of all or a portion of hair, retard further growth, and recovery of skin surface.

Abstract: A microwave ablation system is provided. The microwave ablation system includes a power source. A microwave antenna is adapted to connect to the power source via a coaxial cable that includes inner and outer conductors having a compressible dielectric operably disposed therebetween. The inner conductor in operative communication with a radiating section associated with the microwave antenna. The outer conductor includes a distal end transitionable with respect to each of the inner conductor, compressible dielectric and radiating section from an initial condition wherein the distal end has a first diameter to a subsequent condition wherein the distal end has second diameter. Transition of the distal end from the initial condition to the subsequent condition enhances the delivery of microwave energy from the power source to the inner conductor and radiating section such that a desired effect to tissue is achieved.

Abstract: Technologies are generally described for detecting diseased tissues through fiber optic based Raman spectroscopy, image acquisition, and/or RF induced hyperthermia treatment of the detected tissues in an integrated manner. A fiber optic bundle for carrying optical and RF signals for the spectroscopy, visual imaging, and RF ablation may also be used to detect a temperature of the treated tissue such that level and duration of the RF signal can be controlled for optimum results. A shielding configuration in the form of a coaxial waveguide of the fiber optic bundle may be used to guide and deliver the RF signal. Sources and detectors for the optical and RF signals may be integrated into an endoscopic probe containing the fiber optic bundle or be externally positioned. An integrated or remote controller may be employed to manage the optical imaging, spectroscopy, RF ablation, and thermal sensing operations.

Abstract: A method of regulating temperature at a tissue site comprising measuring sphincter tissue temperature at or near a tissue site, comparing the measured sphincter tissue temperature to a desired temperature, increasing an existing flow rate of a cooling solution to the tissue site if the measured tissue temperature exceeds the desired temperature, and maintaining the existing flow rate of the cooling solution to the tissue site if the measured temperature does not exceed the desired temperature.

Abstract: A catheter used for diagnosing and treating, for example, atrial fibrillation. The catheter includes a catheter shaft that has a proximal portion and a distal portion. The distal portion is adapted to be inserted into a body cavity having tissue to be diagnosed or treated and is disposed remotely from the proximal portion. The distal portion, which may be curved or straight, comprises an outer peripheral wall having an active region, and the distal portion has a cross-sectional configuration along the active region. The cross-sectional configuration is adapted to bias the active region against the tissue to be diagnosed or treated.

Abstract: The invention relates to a method for medical treatment of a mammal, preferably a human, suffering from cancer by applying pulsed radiofrequency (PRF) stimulation before chemotherapy or hormonal therapy. The PRF treatment may be given intravascularly or transcutaneously. In another embodiment, PRF treatment is performed through transcutaneous application of the signal.

Abstract: Disclosed therein is a tip structure for a skin care apparatus. The tip structure includes a first electrode formed on a substrate mounted on the front end part of a tip case and a second electrode formed on the periphery of the front end part of the tip case so as to provide a wide electrode area. The tip structure for the skin care apparatus, which supplies high frequency energy to the skin through electrodes formed at the front end portion of the tip case, includes: a first electrode formed on the substrate mounted on the front end part of the tip case; and a second electrode formed on a peripheral portion of the front end part of the tip case.

Abstract: Methods, kits, apparatus, and compositions for inhibiting a cerebral neurovascular disorder, a muscular headache, or cerebral inflammation in a human patient are provided. The apparatus includes an electronic neural stimulator capable of stimulating a dorsonasal nerve structure associated with pain in a subject, thereby inhibiting the pain, and includes a power supply for providing the neural stimulation; and at least one electrical conduit coupled between the power supply and a dorsonasal nerve structure associated with the cerebral neurovascular disorder in a manner to transmit the neural stimulation to the dorsonasal nerve structure associated with the pain to thereby inhibit the pain. Cerebral neurovascular disorders include migraine and cluster headache. Muscular headaches include tension headaches and muscle contraction headaches.

Abstract: Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.

Abstract: A catheter apparatus for treatment of a human patient is described, the catheter apparatus having a central axis and comprising a shaping structure moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. The shaping structure is configured to have a reverse taper with a structural diameter that varies over the length of the shaping structure such that the structural diameter of the shaping structure at the proximal end is smaller than the structural diameter of the shaping structure at the distal end.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a medical device for modulating nerves. The medical device may include an elongate shaft having a distal region. Two or more electrodes may be positioned adjacent to the distal end region of the elongate shaft. A control unit may supply power and control algorithms to the electrodes. The control algorithm may allow the electrodes to be operated simultaneously and individually.

Abstract: A method in which a location is determined on the skin that is proximate to a sensory nerve that is associated with a painful condition. At least one needle of a cryogenic device is inserted into the location on the skin such that the needle is proximate to the sensory nerve. The device is activated such that the at least one needle creates a cooling zone about the sensory nerve, thereby eliminating or reducing severity of the painful condition.

Abstract: Systems and methods are provided for focused remodeling and downsizing the volume of subcutaneous lipid-rich cells, body contouring, and tightening skin tissue, using controlled heating of the targeted areas on the body. Electromagnetic energy heats skin layers or tissues to achieve an aesthetic effect. The electromagnetic energy may be applied via an applicator without touching the skin. A spacer of insulating or dielectric material may be provided between the applicator and the skin.

Abstract: A cannula assembly, further comprising a cannula body for directing blood from the heart of a patient, having distal and proximal ends and a lumen therebetween. A tip coupled to the distal end of the body, the tip having an opening. A pump for drawing blood into the cannula assembly and dispensing the blood from the cannula assembly and into the patient circulatory system. The lumen of the cannula body further comprises a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being larger than the second inner diameter. A tapered portion defined as a decrease in inner diameter from the first inner diameter to the second inner diameter between the proximal and distal ends, the tapered portion configured to prevent cavitation of the blood within the cannula.

Abstract: The present invention is directed to systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy. In one embodiment of the invention a medical device and associated apparatus and procedures are used to treat dermatological conditions using microwave energy.

Abstract: The disclosure describes a hand-held device that utilizes a mechanical lever system to operate the device with a single hand. The mechanical lever system is coupled to a sliding element within the housing of the hand-held device that slides linearly. The sliding element may be attached to another element that is extended, retracted, or rotated in or out of the device. For example, the hand-held device may be used for prostate ablation therapy. The hand-held device may include an ablation needle electrode that is extended out of a catheter and into a tissue of a patient by depressing an extension lever of the mechanical lever system to deliver ablation therapy. Depressing a retraction lever of the mechanical lever system may retract the needle electrode back into the catheter of the hand-held device. Other variations of the mechanical system and applications of the hand-held device are also described.

Abstract: An apparatus for cosmetic RF skin treatment where the RF energy supply is isolated from the patient treated, such that in course of treatment no undesired current flows through the subject body.

Abstract: The present invention relates to an apparatus for classifying and/or ablating tissue. By directing microwave radiation through a probe (5) into tissue (6) and detecting the amplitude and phase of radiation reflected back through the probe and a reference signal, the tissue type can be classified. An impedance tuner which is actuated by magnetostrictive material (800) is also disclosed.

Abstract: The present invention discloses an acupuncture and moxibustion apparatus with multi-frequency microwave comprising a microwave oscillator A, a power amplifier A, circulator A, a power divider A, a microwave radiator A, a microwave oscillator B, a power amplifier B, a circulator B, a power divider B, a microwave radiator B, a controller, a display screen, and a power supply unit. Two medical frequencies in the international microwave band L are used to avoid the interferences between communication and TV. And the solid state modular microwave source is used, which provides a good thermal penetration, heating homogeneity, and safety performance, as well as high efficiency and long service life. Dual effect of acupuncture using metal needle and heating of acupuncture points by moxibustion is provided. The apparatus can be used to treat multiple human diseases.

Abstract: An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.

Abstract: Radiofrequency (RF) skin treatment devices and methods are provided herein. RF energy is delivered via electrodes in a phase-controlled manner which heats skin volumes below the surface more than the skin surface itself. At least one electrode at least partially encloses at least one other electrode. The combination of controlling the phases of the RF energy delivered to different electrodes and the enclosing configuration of the electrodes allows concentrating the delivered energy in specific regions below the skin surface at a particularly high efficiency. Configurations of the enclosing and the enclosed electrodes, their forms and combinations with other electrodes and the phase polarities applied to the electrodes are also provided.

Abstract: Methods, apparatus, and systems for transcutaneously treating tissue located beneath a skin surface with electromagnetic energy delivered from a treatment electrode. A portion of the treatment electrode is contacted with the skin surface. While maintaining the contact between the portion of the treatment electrode and the skin surface, the electromagnetic energy is delivered from the treatment electrode in a plurality of power pulses through the skin surface to the tissue over a treatment time with a time gap between each consecutive pair of the pulses to lower a level of pain perceived by a patient.

Abstract: A method of resection of an organ employs a handheld microwave waveguide that receives a microwave signal and applies a substantially planar microwave beam into the organ for coagulation of a strip of tissue in an organ providing a barrier against blood loss during resection operations.

Abstract: A system for monitoring ablation size is provided. The system includes a power source including a microprocessor for executing one or more control algorithms. A microwave antenna is configured to deliver microwave energy from the power source to tissue to form an ablation zone. A plurality of spaced-apart electrodes is operably disposed along a length of the microwave antenna. The plurality of spaced-apart electrodes is disposed in electrical communication with one another and each of the plurality of spaced-apart electrodes has a threshold impedance associated therewith corresponding to the radius of the ablation zone.

Abstract: An apparatus and method for ablating tissue is disclosed. The apparatus comprises a source of microwave radiation (1), a probe (5) for directing the microwave radiation into tissue, one or more detectors for detecting the power and phase of the microwave radiation and an impedance adjuster (50) for adjusting impedance so as to minimize the amount of microwave radiation which reflected back through the probe. The detector or detectors use a local oscillator (230) to derive the phase information. A modulator for modulating the microwave radiation to a cutting frequency is also disclosed.

Abstract: A skin treatment apparatus that includes, a disposable electrode carrier with a plurality of voltage-applying dome-shaped elements protruding from the surface of the electrode carrier. Further, the protruding elements are spaced apart in a pattern. The apparatus operates to apply a voltage to at least some of the protruding elements. The apparatus applies a voltage to the protruding elements with a magnitude that is sufficient to result in an electrical break down of the skin and thereby cause electric current enabling the desired treatment.

Abstract: Methods are provided for ablating tissue by implanting a plurality of electrode devices within the tissue to be treated and exposing the implanted electrode devices with RF energy conveyed from a separate electrode device. In this manner, a greater region of tissue is ablated than what would normally be ablated with the separate electrode device. In addition, the implanted electrode devices can create a roadmap that allows the progress of the treatment to be managed during follow-ups. The implanted electrode devices can be variously delivered to the tissue, for example, by detaching the electrode devices from one or more delivery devices. For example, a core wire with an electrolytically detachable junction can be used to separate the electrode device from the core wire. Pusher rods with mechanically detachable junctions are also contemplated.

Abstract: A catheter system for repairing an annular organ structure of a patient, comprising: intimately contacting the annular organ structure by a tissue-contactor member having energy-delivering elements; and delivering tissue-shrinkable energy at the annular organ structure through the elements, wherein the tissue-shrinkable energy is applied at a distance wirelessly from the elements sufficient to shrink and tighten the organ structure. Tissue-shrinkable energy is infrared energy, ultrasound energy, focused ultrasound energy, ultrasound energy, radiofrequency energy, microwave energy, electromagnetic energy, laser energy, or a combination thereof.

Abstract: The present invention provides a system and method to non-invasively deliver a therapeutic amount of energy to a treatment site to fragment particulate material. More specifically, an external power source is provided for transmitting energy non-invasively through the skin and body of a patient to a medical implant. The medical implant, including an energy focusing device, is surgically positioned at the treatment site. The energy focusing device is configured to receive the transmitted energy and directing therapeutic energy to the treatment site to fragment particulate material.

Abstract: A catheter for use in a patient's heart, especially for mapping a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal a mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for single-handed manipulation of various control mechanisms that can deflect the intermediate section and contract the mapping assembly by means of a deflection control assembly and a linear control assembly. The deflection control assembly has a deflection arm and a rocker member. The linear control assembly has a linear control member, an inner rotational member and a cam. A pair of puller members are responsive to the deflection control assembly to bi-directionally deflect the intermediate section. A third puller member is responsive to the linear control assembly to contract the generally circular portion of the mapping assembly.

Abstract: The present invention relates to a treatment device using high frequency and provides a treatment device using high frequency comprising: a main body comprising a high frequency generation portion inside; a contact type hand piece comprising a first electrode portion for providing high frequency energy generated in the high frequency generation portion to the surface of the skin, and is detachably formed at an fastening portion of the main body; an invasive hand piece comprising a second electrode portion for providing high frequency energy generated in the high frequency generation portion to the inside of the skin, and is detachably formed at an fastening portion of the main body; and a control portion for controlling the high frequency energy provided from the high frequency generation portion to the first electrode portion or the second electrode portion.

Abstract: An electromedical device for the non-invasive reduction or removal of subcutaneous adipose tissue, comprising an energy source which provides a high-frequency alternating current, comprising at least two individual emitters which are fed by the energy source and which are designed to emit high-frequency electromagnetic waves into subcutaneous adipose tissue, and comprising a directivity control which is coupled with the individual emitters and which controls the individual emitters in such a way that, by direction and field concentration of the high-frequency electromagnetic waves emitted by the individual emitters, a total electromagnetic field with a desired field geometry can be produced in the subcutaneous adipose tissue.

Abstract: The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment.

Abstract: Apparatus and methods to modulate bladder function are provided. An energy delivery apparatus can include an elongated shaft, a distal region coupled to the elongated shaft, and an energy delivery element configured to deliver energy to non-superficial target tissue within a trigone region of a bladder wall of a human bladder to modulate bladder function.