With Temperature Sensing Patents (Class 607/102)
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Patent number: 6090105Abstract: An ablation apparatus includes an introducer with a distal end sufficiently sharp to penetrate tissue. An energy delivery device is configured to be coupled to an energy source. The energy delivery device includes a first electrode and a second electrode each with a tissue piercing distal portion. The first and second electrodes are at least partially positionable in the introducer and deployable from the introducer at a selected tissue site to an expanded state. In the expanded state the deployed first and second electrodes distend laterally away from the introducer with a radius of curvature to form a shaped array of deployed electrodes at the tissue site when positioned at the selected tissue site. The first electrode distal portion and the second electrode distal portion are each at least partially made of a shaped memory alloy material that displays stress induced martensite behavior above body temperature. A cable couples the energy source to the energy delivery device.Type: GrantFiled: November 17, 1997Date of Patent: July 18, 2000Assignee: Rita Medical Systems, Inc.Inventors: John Zepeda, Chaya Hirsch, Kee Lee, Edward J. Gough
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Patent number: 6081749Abstract: The invention provides improved devices, methods, and systems for shrinking of collagenated tissues, particularly for treating urinary incontinence in a noninvasive manner by directing energy to a patient's own support tissues. This energy gently heats fascia and other collagenated support tissues, causing them to contract. The energy will preferably be applied between a pair of large plate electrodes having cooled flat electrode surfaces. Such cooled plate electrodes are capable of directing electrical energy through an intermediate tissue and into fascia while the cooled electrode surface prevents injury to the intermediate tissue. Ideally, the plate electrode comprises an electrode array including discrete electrode surface segments so that the current flux can be varied to selectively target the fascia.Type: GrantFiled: August 13, 1997Date of Patent: June 27, 2000Assignee: SURx, Inc.Inventors: Frank Ingle, Garry Carter
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Patent number: 6063078Abstract: The present invention is a system for ablating tissue within a body, the system having: an energy source providing a level of energy which is non damaging to the cellular structures of the body tissue, a catheter coupled to the energy source, the catheter having an electrode; and means for sensing the temperature of the electrode while also sensing the amount of energy which is non damaging to the cellular structures of the body tissue is delivered to the electrode, the sensing means coupled to the catheter and coupled to the energy source wherein the degree to which the electrode contacts the heart tissue (e.g. no contact, moderate contact, good contact or excellent contact) may be determined.Type: GrantFiled: March 12, 1997Date of Patent: May 16, 2000Assignee: Medtronic, Inc.Inventor: Frederik H. M. Wittkampf
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Patent number: 6064914Abstract: A hydrodissection apparatus for treatment of the prostate of a patient using a moving apparatus for moving the prostate away from the adjacent rectum and using heat to heat the prostate while keeping the rectum protected from any damage that could be caused by the heat.Type: GrantFiled: April 1, 1998Date of Patent: May 16, 2000Inventor: John R. Trachtenberg
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Patent number: 6059778Abstract: An apparatus for delivering energy to a biological site includes an electrode device having a plurality of electrodes, the electrode device positioned proximal the biological site. A power control system supplies power having a controllable phase angle to each of the electrodes. A backplate is also positioned proximal the biological site so that the biological site is interposed between the electrode device and the backplate. The backplate is maintained at the reference voltage level in relation to the power. The power control system controls the phase angle of the power so that the current flow between the electrodes and between the electrodes and the backplate results in the continuity and depth of lesions desired. In a preferred embodiment, the electrodes are arranged in a substantially linear array.Type: GrantFiled: May 5, 1998Date of Patent: May 9, 2000Assignee: Cardiac Pacemakers, Inc.Inventor: Marshall L. Sherman
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Patent number: 6056745Abstract: Systems and methods for ablating body tissue use an electrode for contacting tissue to form a tissue-electrode interface. The electrode is coupled to a source of ablation energy for transmitting ablation energy at a prescribed ablation power level into tissue to form, over a prescribed ablation time period, a therapeutic result. The therapeutic result includes a lesion that extends beneath the tissue-electrode interface to a boundary depth between viable and nonviable tissue and a maximum tissue temperature developed within the lesion between the tissue-electrode interface and the boundary depth. The systems and methods include an element to cool the electrode. An input element inputs a desired therapeutic result including at least a targeted lesion boundary depth.Type: GrantFiled: October 27, 1997Date of Patent: May 2, 2000Assignee: EP Technologies, Inc.Inventors: Dorin Panescu, David K. Swanson, Sidney D. Fleischman
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Patent number: 6053913Abstract: An ablation apparatus for treating tissues or atherosclerosis on a patient having a prior angioplasty procedure, the ablation apparatus comprising a rapid exchange stented balloon catheter having a reversibly collapsible stent secureed around the balloon and RF energy applied through the deployed stent to the tissue underlying the stent for therapeutic ablation purposes.Type: GrantFiled: September 10, 1998Date of Patent: April 25, 2000Inventors: Lily Chen Tu, Hosheng Tu
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Patent number: 6053912Abstract: Systems and associated methods for ablating body tissue employ an electrode for contacting tissue to form a tissue-electrode interface. The electrode is adapted to be connected to a source of ablation energy to conduct ablation energy for transmission by the electrode into tissue at the tissue-electrode interface. The systems and methods also include an element to cool the electrode. The systems and methods hold a tissue temperature sensing element in a carrier in thermal conductive contact with tissue beneath the tissue-electrode interface. The systems and methods include a controller that is coupled to the tissue temperature sensing element to control either the supply of ablation energy, or the rate at which the electrode is cooled, or both based, at least in part, upon temperature sensed by the temperature sensing element.Type: GrantFiled: October 1, 1997Date of Patent: April 25, 2000Assignee: EP Techonologies, Inc.Inventors: Dorin Panescu, David K. Swanson, Sidney D. Fleischman, Thomas M. Bourne
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Patent number: 6050993Abstract: A medical device for treating the hemorrhoid, or reducing the dilatation of cellular tissues, wherein an elongate tubular shaft comprises at least one coil loop electrode means disposed at its distal end portion of the shaft, a RF energy generating means, and a means for pressing the electrode means against the target tissue to effect the ablation and the pressure therapy for the hemorrhoid tissues.Type: GrantFiled: July 27, 1998Date of Patent: April 18, 2000Assignee: Quantum Therapeutics Corp.Inventors: Lily Chen Tu, Hosheng Tu
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Patent number: 6045550Abstract: The non-joined thermocouple electrode configuration, for use in an RF ablation catheter for ablating biological tissue such as cardiac tissue, allows temperature to be monitored at two locations of a band electrode while only using a single pair of thermocouple wires. The thermocouple wires are connected to the electrode at separate locations. They preferably are formed of metallic materials having Seebeck coefficients that are substantially equal in magnitude but opposite in sign relative to the electrode material connecting the two. In the case of a band electrode, the two thermocouple wires are preferably spaced apart on the band electrode so that the first junction contacts the tissue having a first temperature and the second junction contacts circulating blood having a second temperature.Type: GrantFiled: May 5, 1998Date of Patent: April 4, 2000Assignee: Cardiac Peacemakers, Inc.Inventors: John A. Simpson, Marshall L. Sherman
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Patent number: 6033403Abstract: An improved catheter system having an electrode means at its tip section capable of delivering a long continuous linear lesion in tissues of a patient. A catheter system suitable for radiofrequency ablation of cardiac tissues comprising an electrode means mounted on the distal tip section of the catheter shaft, the electrode means having a wire and a plurality of ring electrodes, the wire having a wire core section, a wire distal end and a wire proximal end, wherein a first ring electrode is secured to the wire distal end and a second ring electrode is secured to the wire proximal end. The catheter system also comprises an external RF current generator, wherein a RF current is delivered to the electrode means.Type: GrantFiled: October 8, 1998Date of Patent: March 7, 2000Assignee: Irvine Biomedical, Inc.Inventors: Hosheng Tu, Cary Hata
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Patent number: 6030382Abstract: Devices and methods for ablating body tissue. The devices include a support body and at least one elongated electrode. Adjacent windings are spaced apart to impart enhanced flexibility to the elongated electrode.Type: GrantFiled: April 3, 1998Date of Patent: February 29, 2000Assignee: EP Technologies, Inc.Inventors: Sidney D. Fleischman, Russell B. Thompson, Dorin Panescu, David K. Swanson
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Patent number: 6030379Abstract: Systems and methods for ablating body tissue use an ablation element for contacting tissue to form a tissue interface. The ablation element is adapted to be connected to a source of ablation energy to conduct ablation energy for transmission by the ablation element into tissue at the tissue interface. The systems and methods include a tissue temperature sensing element held in a carrier in thermal conductive contact with tissue beneath the tissue interface. A mechanism attached to the carrier selectively advances the carrier relative to the ablation element to different depths beneath the tissue interface. A controller is coupled to the mechanism and to the tissue temperature sensing element to control advancement of the carrier beneath the tissue interface based, at least in part, upon tissue temperatures sensed by the sensing element beneath the tissue interface. Preferably, the controller controls the mechanism to locate the sensing element at the depth where the hottest sensed tissue temperature exists.Type: GrantFiled: September 22, 1997Date of Patent: February 29, 2000Assignee: EP Technologies, Inc.Inventors: Dorin Panescu, Thomas M. Bourne
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Patent number: 6029091Abstract: A catheter system comprising a delivery catheter and an inner catheter, wherein the inner catheter is deployable and has a plurality of electrodes on the lattices of a trellis fixture. During a deployed state, the trellis fixture is fully extended to have a series of electrodes on a two-dimensional plane for mapping and/or ablation purposes.Type: GrantFiled: July 9, 1998Date of Patent: February 22, 2000Assignee: Irvine Biomedical, Inc.Inventors: Alan de la Rama, Nadir Saoudi
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Patent number: 6024743Abstract: An apparatus to treat an uterus includes an expandable member configured to be positioned in a uterine cavity in a non-deployed, state, receive an expansion media and extend to a deployed state. At least a portion of the expansion media is released through an expandable member exterior surface. Upon removal of at least a portion of the expansion from the expandable member, the expandable member contracts to a non-deployed state. An energy delivery device is coupled to the expandable member. A frame member is positionable in the interior of the expandable member. The frame member includes a first arm coupled to a second arm. The frame member has a non-deployed state and a deployed state where the first and second arms distend away from each other. Each of the expandable member and the frame member have a non-deployed size to be introduced into the uterine cavity.Type: GrantFiled: February 4, 1998Date of Patent: February 15, 2000Inventor: Stuart D. Edwards
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Patent number: 6026331Abstract: A probe (1) is designed to propagate and radiate microwave electromagnetic energy in a controlled fashion. The probe (1) includes at least one waveguide (2) of cross-section which would not normally pass microwaves at the operational frequency. The waveguide (2) therefore includes dielectric material (5), such as alumina, in the form of a rod an exposed portion of which forms an antenna. The probe is preferably for use in endometrial ablation and therefore the reduced dimension of the waveguide can be made compatible with the narrow neck of the uterus.Type: GrantFiled: April 29, 1996Date of Patent: February 15, 2000Assignee: Microsulis LimitedInventors: Ian Feldberg, Nigel Cronin, Martyn Evans, Nicholas Sharp, Suzanne Smith
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Patent number: 6009351Abstract: A system and method for treating a prostate of a patient is disclosed. The system includes a rectal probe for insertion into a rectum of the patient. A fluid supply system connected to the rectal probe supplies fluid to the rectal probe. A microwave radiation system, which is positioned anterior to the rectum of the patient, heats tumorous tissue of the prostate. The combination of the microwave radiation system and the fluid supplied to the rectal probe creates an asymmetrical heating pattern about a urethra of the patient and protects tissue adjacent to the rectal probe from thermal damage during radiation of the tumorous tissue.Type: GrantFiled: July 14, 1997Date of Patent: December 28, 1999Assignee: Urologix, Inc.Inventor: Jonathan L. Flachman
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Patent number: 5997534Abstract: A medical ablation device system for treating endometrosis, gingivae or reducing the mass of cellular tissue, wherein an elongate tubular element comprises an electrode means disposed at its distal section, the energy generating means, and means for generating rotational sweeping force at the distal section of the tubular element to effect the heat treatment and the rotational sweeping massage therapy for the target tissue.Type: GrantFiled: June 8, 1998Date of Patent: December 7, 1999Inventors: Hosheng Tu, Lily Chen Tu
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Patent number: 5992419Abstract: Disclosed are three embodiments of a method for determining the formation of a "biological stent" for permanently maintaining the widened bore portion of the urethra of a male patient undergoing treatment for a disease of the prostate. In this treatment, the bore portion is first temporarily widened by squeezing pressure on urethral tissue thereof applied by an inflated balloon of a microwave balloon catheter inserted in the urethera and then microwave energy sufficient to form the "biological stent" is applied to the urethral tissue. The first embodiment involves noting an observable drop in the measured value of the inflation pressure inflating the balloon when the urethral tissue has been sufficiently heated to effect a noticeable drop in the elasticity of the irradiated urethral tissue.Type: GrantFiled: August 20, 1998Date of Patent: November 30, 1999Assignee: MMTC, Inc.Inventors: Fred Sterzer, Daniel D. Mawhinney
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Patent number: 5974343Abstract: A probe, particularly a urethral probe, for the heating of tissue by microwaves and for the measurement of temperature by radiometry. The probe comprises, on the one hand, at least one elongated antenna (1) formed by at least one conductive portion (2, 2') rolled up in a helicoidal manner on an elongated dielectric support (3) having a front end and a rear end, on the other hand, electrical connections (4) for the transfer of microwave signals toward and from the antenna, connected to a corresponding external generator and radiometer, and, finally, a catheter (5) covering the antenna (1) and, as the case may be, at least the portion of the electrical connections adjacent the antenna (1). The central dielectric support (3) has structure for circulation of thermostatic fluid of the antenna (1) at least present within the tubular channel delimited by the helicoidal conductor portion (2, 2'), this structure being connected to structure (6, 6', 6", 6'") for the supply and evacuation of the thermostatic fluid.Type: GrantFiled: January 13, 1997Date of Patent: October 26, 1999Assignee: Bruker SAInventors: Christian Brevard, Michel Weiss, Bernard Loewenguth, Jean-Pierre Mabire
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Patent number: 5968005Abstract: A medical device for treating canker sores, wherein a flexible RF electrode means comprising a therapeutic agent delivery means, is inserted into the mouth; the electrode means being placed against and/or surrounding the canker sore region; RF energy is applied for a predetermined time and temperature to the canker sore tissue through the electrode means to cause internal lesions; and delivering a therapeutic agent to heal the tissues thereafter for a pre-determined duration.Type: GrantFiled: January 7, 1998Date of Patent: October 19, 1999Inventor: Hosheng Tu
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Patent number: 5964791Abstract: A device for heat treatment of body tissue, including heating means (10) for local heating of the body tissue, and temperature sensing means (11) for sensing the tissue temperature, said heating means being enclosed in a catheter (12). A first temperature sensing means (11) is connected to a first carrier (13), which is made to be advanced through a first opening in catheter (12), and said first carrier (13) is equipped with a pointed tip for insertion into such body tissue that is to be heat-treated.Type: GrantFiled: November 14, 1997Date of Patent: October 12, 1999Assignee: ProstaLund Operations ABInventor: Magnus Bolmsjo
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Patent number: 5957922Abstract: A transurethral radio frequency apparatus for ablation of the prostate gland through the urethra formed by a wall, a probe consisting of a flexible elongate tubular member with proximal and distal extremities and sized so as to be adapted to be inserted into the urethra, and an ablation electrode carried by the distal extremity of the flexible elongate member. The flexible elongate tubular member is provided with first and second flow lumens for delivering a cooled fluid to the ablation electrode to cool the same. Means are connected to the probe to supply a coolant solution to the probe, to supply radio frequency energy to the electrode while it is being cooled, and to monitor the temperature of the ablation electrode so that the ablation electrode is maintained at a temperature below a predetermined temperature to spare the urethral wall from irreversible damage from the radio frequency energy delivered to the ablation electrode.Type: GrantFiled: September 12, 1997Date of Patent: September 28, 1999Assignee: Vidamed, Inc.Inventor: Mir A. Imran
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Patent number: 5957961Abstract: A catheter ablation system including a catheter having a distal segment carrying at least one electrode extending along the segment and having a number of temperature sensors arranged along the distal segment adjacent the electrode, each providing an output indicative of temperature. The catheter is coupled to a power source which provides R-F energy to the electrode and with temperature processing circuitry coupled to the temperature sensors and the power source which controls power output from the power source as a function of the outputs of the temperature sensors. In a preferred embodiment, the temperature processing circuitry includes circuitry for comparing the temperature indicated by the temperature sensors to a known reference sensor and circuitry for disabling subsequent use of an output of one of the sensors if the output from the sensor differs from the referenced temperature by more than a defined value.Type: GrantFiled: January 9, 1998Date of Patent: September 28, 1999Assignee: Medtronic, Inc.Inventors: Mark A. Maguire, Kevin C. Ladd, John W. Gaiser, Le T. Le
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Patent number: 5954719Abstract: A catheter-based system for operating a RF ablation generator comprising a RF splitter for delivering RF energy to a plurality of electrodes; a low-pass filter located between the RF splitter and an external EKG monitor for displaying real-time signal to said EKG monitor; and a software program having temperature data input from a plurality of temperature sensors and signal output capability, wherein the software program sends out signals to the RF splitter being adapted to control the RF energy output to each electrode.Type: GrantFiled: March 23, 1998Date of Patent: September 21, 1999Assignee: Irvine Biomedical, Inc.Inventors: Peter Cheng Chen, Tho Hoang Nguyen
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Patent number: 5948009Abstract: An ablation device for treating canker sores or reducing the mass of cellular tissue, wherein an elongated tubular element includes at least one electrode disposed at its distal section, RF energy generating means, and means for generating vibration at the distal section of the tubular element to effect the ablation and the vibrational massage therapy for the tissue.Type: GrantFiled: March 6, 1998Date of Patent: September 7, 1999Inventor: Hosheng Tu
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Patent number: 5938692Abstract: A catheter shaft carries a coaxial cable, the terminal end of which contains a dipole antenna with opposing first and second helical elements. The first and second helical elements originate from a common connection to an outer conductor of the coaxial cable. The first and second helical elements are formed by winding flat wire around an outer insulator of the coaxial cable near a terminal end of the coaxial cable. A variable, controllable impedance is connected between an inner conductor of the coaxial cable and a point on the second helical element where the resistive component of the antenna's impedance matches the characteristic impedance of the coaxial cable. The impedance match minimizes reflective losses of the antenna, thereby maximizing power transferred to the antenna. The antenna has an effective electrical length which is equal to one-half the wavelength of the radiation emitted, independent of the physical length of the antenna.Type: GrantFiled: March 26, 1996Date of Patent: August 17, 1999Assignee: Urologix, Inc.Inventor: Eric N. Rudie
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Patent number: 5935124Abstract: A catheter comprises a catheter body, a tip section, and a control handle. The catheter body has proximal and distal ends and at least one lumen extending therethrough. The control handle is located at the proximal end of the catheter body. The tip section has proximal and distal ends and at least one lumen therethrough, with the proximal end of the tip section being fixedly attached to the distal end of the catheter body. A tip electrode is fixedly attached at the distal end of the tip section. The tip electrode has a blind hole extending therethrough. A wire, preferably a puller wire, extends and is fixedly attached into the blind hole of the tip electrode. At least two temperature sensors are fixedly attached along the length of the wire within the blind hole.Type: GrantFiled: December 2, 1997Date of Patent: August 10, 1999Assignee: Cordis Webster, Inc.Inventors: Katherine Klumb, Kristine Fuimaono
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Patent number: 5931835Abstract: A radio-frequency ablation system is disclosed in which the power, voltage, or temperature delivered to multiple electrodes may be dynamically controlled, and in which the electrodes may be simultaneously energized in phase with each other to achieve a desired lesion pattern. The system comprises a multiple electrode ablation catheter, each electrode having a temperature sensor operatively associated therewith. Each electrode is energized by its own RF amplifier, and all of the electrodes are driven in phase with each other by a common sine wave oscillator. A feedback network controls the degree of amplification of the separate RF amplifiers. According to a further aspect of the invention, a modular power supply arrangement is disclosed which is configurable to dynamically control the power, voltage, or temperature delivered to multiple electrodes of a multipolar ablation device.Type: GrantFiled: June 13, 1997Date of Patent: August 3, 1999Assignee: C. R. BardInventor: Sean Mackey
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Patent number: 5931860Abstract: A system for treatment of benign prostatic hyperplasia within intraprostatic tissue surrounding a urethra is disclosed. The system includes an intraurethral catheter having an intraurethral catheter shaft. An antenna is located within the catheter shaft for delivering heat to the intraprostatic tissue surrounding the urethra. Coolant fluid is circulated through a chamber located between the catheter shaft and the urethral wall.Type: GrantFiled: June 23, 1997Date of Patent: August 3, 1999Assignee: Urologix, Inc.Inventors: John M. Reid, James V. Kauphusman, Christopher H. Porter, Bruce H. Neilson
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Patent number: 5928229Abstract: An ablation apparatus has a multiple antenna device with a primary antenna and a secondary antenna positionable in a lumen of the primary antenna. The secondary antenna is at least partially deployable from the primary antenna in a lateral direction relative to a longitudinal axis of the primary antenna with at least one radius of curvature. A distal end of the primary antenna is sufficiently sharp to pierce tissue. The primary and secondary antennas are configured to provide a selectable geometric ablation of a selected tissue mass. An insulation sleeve is positioned on an exterior of the primary antenna. One or more cables are coupled to the multiple antenna device.Type: GrantFiled: October 30, 1997Date of Patent: July 27, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5925042Abstract: An ablation treatment apparatus has a multiple antenna device. The multiple antenna device includes a primary antenna with a lumen, a longitudinal axis and an ablative surface area of length L.sub.1. The multiple antenna device also includes a secondary antenna that is positionable in the primary antenna. A secondary antenna distal end is deployed at a selected tissue site from the primary antenna lumen in a lateral direction relative to the longitudinal axis. A sensor is at least partially positioned at an exterior of the secondary antenna distal end at a distance L.sub.2 from the primary antenna along the secondary antenna distal end. L.sub.2 is at least equal to 1/3 L.sub.1. An energy source is coupled to the primary antenna.Type: GrantFiled: November 3, 1997Date of Patent: July 20, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5919218Abstract: A fluid flow cartridge for seating in an opening into a microwave heating cavity comprises a tubing support having an electrically conductive surface dimensioned to substantially close that opening and an elongated bobbin portion projecting from that surface. The cartridge also includes a selected length of tubing wound around the bobbin portion to form a coil, opposite end segments of the tubing extending from the coil through the conductive support surface and away from said support. Preferably, the coil has straight tubing segments on opposite sides of the coil spaced apart one quarter wavelength or integral multiple thereof at the operating frequency of the heating cavity.Type: GrantFiled: January 30, 1995Date of Patent: July 6, 1999Assignee: Microwave Medical SystemsInventor: Kenneth L. Carr
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Patent number: 5919219Abstract: A method for tightening a surface of a skin with an underlying collagen containing tissue applies RF energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and become inflated to substantially conform a contacting exterior surface of the membrane to a skin layer. The membrane includes a cooling lumen for receiving cooling fluid. One or more thermal electrodes positioned in the membrane and transfers thermal energy to the electrolytic solution. The electrolytic solution and cooling fluid creates a reverse thermal gradient from the skin surface to the underlying collagen tissue. A thermal power source is coupled to the thermal electrodes, and a source of electrolytic solution is coupled to the membrane.Type: GrantFiled: August 19, 1997Date of Patent: July 6, 1999Assignee: Thermage, Inc.Inventor: Edward W. Knowlton
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Patent number: 5916241Abstract: An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shafts. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.Type: GrantFiled: July 30, 1997Date of Patent: June 29, 1999Assignee: Urologix, Inc.Inventors: Eric N. Rudie, Bruce H. Neilson, James V. Kauphusman
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Patent number: 5916240Abstract: An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.Type: GrantFiled: July 15, 1997Date of Patent: June 29, 1999Assignee: Urologix, Inc.Inventors: Eric N. Rudie, Bruce H. Neilson, James V. Kauphusman
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Patent number: 5913855Abstract: An ablation treatment apparatus has a multiple antenna device. The multiple antenna device includes a primary antenna with a lumen and a longitudinal axis, and a secondary antenna positionable in the lumen. At a selected tissue site the secondary antenna is deployed in a lateral direction relative to the longitudinal axis of the primary antenna. At least a portion of a distal end of the secondary antenna is structurally less rigid than the primary antenna. The primary antenna is constructed to be rigid enough to be introduced through tissue. A cable couples one or both of the antennas to an energy source.Type: GrantFiled: November 3, 1997Date of Patent: June 22, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5906614Abstract: Systems and methods employ an energy emitting electrode to heat tissue. The systems and methods derive a temperature prediction for a future time period. The systems and methods control the application of energy to the energy emitting electrode based, at least in part, upon the temperature prediction.Type: GrantFiled: February 18, 1997Date of Patent: May 25, 1999Assignee: EP Technologies, Inc.Inventors: Roger A. Stern, Dorin Panescu
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Patent number: 5893885Abstract: A multi-electrode ablation catheter comprises a plurality of thick-walled gold alloy electrodes mounted on the tip section of an elongated electrophysiology catheter. Each electrode is electrically connected to a switching unit by leads comprising paired copper and constantan wires. The switching unit is electrically connected to an RF generator, a temperature monitor and an ECG monitor. The switching unit enables an operator to switch between a first mode for monitoring ECG and a second mode for delivering RF energy for tissue ablation to a selected electrode and monitoring the temperature of that electrode. The copper wire of the lead delivers RF energy and the copper wire and constantan wire combine to form a thermocouple for temperature monitoring.Type: GrantFiled: November 1, 1996Date of Patent: April 13, 1999Assignee: Cordis Webster, Inc.Inventor: Wilton W. Webster, Jr.
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Patent number: 5891134Abstract: An apparatus, system, and method for treating body tissue using controlled application of heat includes a control unit providing electrical power to a bipolar electrode positioned within an expandable member filled with conductive fluid. Electrical power applied to the bipolar electrode by the control unit causes current to pass from the active electrode, into the conductive fluid, and to the return electrode, thereby heating the conductive fluid. The temperature of the conductive fluid is monitored by the control unit, and power is increased and decreased in accordance with a comparison of the monitored temperature against the desired temperature range. The control unit also includes a pressure sensor for regulating the pressure in the bladder. Pressure and temperature displays and other operator controls are located on the control unit.Type: GrantFiled: September 24, 1996Date of Patent: April 6, 1999Inventors: Colin Goble, Robert Warner
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Patent number: 5871524Abstract: An apparatus applies radiant energy through the skin to an underlying subcutaneous layer or deeper soft tissue layers that includes loculations of fat with fibrous septae made of collagen tissue. This creates a desired contour effect without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane conforms a contacting exterior surface of the membrane to a skin layer. One or more thermal electrodes positioned in the membrane. A focussing element focuses thermal energy to the underlying collagen tissue. The focusing element and the electrolytic solution create a reverse thermal gradient from the skin to the collagen tissue. A thermal power source is coupled to the thermal electrodes.Type: GrantFiled: February 3, 1997Date of Patent: February 16, 1999Assignee: Thermage, Inc.Inventor: Edward W. Knowlton
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Patent number: 5865788Abstract: A method and an apparatus is disclosed for delivering controlled heat to perform ablation to treat the benign prosthetic hypertrophy or hyperplasia (BPH). According to the method and the apparatus, the energy is transferred directly into the tissue mass which is to be treated in such a manner as to provide tissue ablation without damage to surrounding tissues. Automatic shut-off occurs when any one of a number of surrounding areas to include the urethra or surrounding mass or the adjacent organs exceed predetermined safe temperature limits. The constant application of the radio frequency energy over a maintained determined time provides a safe procedure which avoids electrosurgical and other invasive operations while providing fast relief to BPH with a short recovery time. The procedure may be accomplished in a doctor's office without the need for hospitalization or surgery.Type: GrantFiled: May 23, 1996Date of Patent: February 2, 1999Assignee: Vidamed, Inc.Inventors: Stuart D. Edwards, Hugh R. Sharkey, Ingemar H. Lundquist, Ronald G. Lax, Bruno Strul
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Patent number: 5861021Abstract: A method of applying microwave energy to cardiac tissue uses a catheter adapted for insertion into a cardiac chamber and which includes a microwave antenna, a cooling lumen structure, and an inflatable cooling balloon. Necrosing levels of microwave energy are delivered from the microwave antenna to diseased cardiac tissue spaced from the catheter. Tissues immediately surrounding the catheter are cooled and microwave energy emitted by the antenna is selectively absorbed by the cooling lumen structure surrounding the antenna. The cooling balloon of the catheter is positioned adjacent the antenna and partially surrounds the cooling lumen structure on one side of the catheter to provide additional cooling capability and additional microwave energy absorption on the side of the catheter opposite the diseased cardiac tissue to prevent unwanted heating of blood within the cardiac chamber.Type: GrantFiled: December 20, 1996Date of Patent: January 19, 1999Inventors: Scott P. Thome, Eric N. Rudie, Mitchell Dann, Teruo T. Hirose
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Patent number: 5853409Abstract: An apparatus for ablating body tissue has an electrode for contacting tissue to transmit ablation energy. A tissue temperature sensing element is held in a thermally conducting carrier on the electrode. The carrier holds the tissue temperature sensing element in thermal conductive contact with tissue, while keeping the temperature sensing element in isolation from thermal conductive contact with the electrode. The carrier has prescribed thermal conductive characteristics that significantly improve the sensitivity of the temperature sensing element to tissue temperature and not the temperature of the electrode.Type: GrantFiled: January 27, 1997Date of Patent: December 29, 1998Assignee: E.P. Technologies, Inc.Inventors: David K. Swanson, Sidney D. Fleischman, Thomas M. Bourne, Dorin Panescu
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Patent number: 5849028Abstract: An electrophysiology catheter suitable for radiofrequency ablation of cardiac tissue comprises an elongate catheter shaft wherein a distal tip section having multiple long electrodes and multiple temperature sensors in the proximity of the tissue contact sites and further comprising a close-loop temperature control mechanism for each electrode with at least a temperature sensor on an adjacent tiny ring.Type: GrantFiled: May 16, 1997Date of Patent: December 15, 1998Assignee: Irvine Biomedical, Inc.Inventor: Peter Cheng Chen
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Patent number: 5843144Abstract: A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter into a urethra to position a microwave antenna located within the catheter adjacent a prostatic region of the urethra. A microwave antenna is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue to heat the prostatic tissue surrounding the microwave antenna at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue.Type: GrantFiled: June 26, 1995Date of Patent: December 1, 1998Assignee: Urologix, Inc.Inventors: Eric N. Rudie, Mitchell Dann, John M. Reid, Bruce H. Neilson, James V. Kauphusman, James E. Burgett, Stanley E. Kluge, Steven W. Norsted
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Patent number: 5837001Abstract: A radio-frequency ablation system is disclosed in which the power, voltage, or temperature delivered to multiple electrodes may be dynamically controlled, and in which the electrodes may be simultaneously energized in phase with each other to achieve a desired lesion pattern. The system comprises a multiple electrode ablation catheter, each electrode having a temperature sensor operatively associated therewith. Each electrode is energized by its own RF amplifier, and all of the electrodes are driven in phase with each other by a common sine wave oscillator. A feedback network controls the degree of amplification of the separate RF amplifiers. According to a further aspect of the invention, a modular power supply arrangement is disclosed which is configurable to dynamically control the power, voltage, or temperature delivered to multiple electrodes of a multipolar ablation device.Type: GrantFiled: December 8, 1995Date of Patent: November 17, 1998Assignee: C. R. BardInventor: Sean Mackey
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Patent number: 5827277Abstract: A method and apparatus for ablating at least a portion of a nasal concha. The apparatus includes a catheter having a distal portion with a dimension configured for positioning through a nostril of a patient into a nasal meatus adjacent a nasal concha, and an energy delivery device coupled to the catheter distal portion including one or more energy delivering probes extendable from the catheter distal portion a sufficient distance to be inserted into an interior of the nasal concha to deliver ablative energy therein. The distal portion of the apparatus may also include an expandable member, expansion of the expandable member within the nasal meatus immobilizing the distal portion within the nasal meatus.Type: GrantFiled: January 29, 1997Date of Patent: October 27, 1998Assignee: Somnus Medical Technologies, Inc.Inventor: Stuart D. Edwards
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Patent number: 5807395Abstract: A methods and apparatuses for ablation or hyperthermic treatment of body tissue are disclosed, wherein the application of radio-frequency ablative or hyperthermic energy is accompanied by the infusion of a conductive solution into the tissue, such that a virtual electrode is created. The virtual electrode results from the increased conductivity of the tissue in the area being treated due to the presence of conductive solution, such that the area of tissue being treated is enlarged as compared with non-fluid-assisted application of energy. In one embodiment, a catheter having a hollow helical electrode/needle on the distal end thereof is provided, such that the electrode/needle can be screwed into the tissue to be treated. A conductive fluid, such as saline, saturated saline, or Ringer's solution, is infused into the tissue to be treated via the hollow electrode and a lumen extending along the length of the catheter.Type: GrantFiled: April 22, 1997Date of Patent: September 15, 1998Assignee: Medtronic, Inc.Inventors: Peter M. J. Mulier, Michael F. Hoey
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Patent number: 5800432Abstract: Systems and methods for ablating body tissue using actively cooled electrodes deploy the electrode for contacting tissue to form a tissue-electrode interface. The systems and methods conduct ablation energy to the electrode for transmission by the electrode into tissue at the tissue-electrode interface. The systems and methods simultaneously cool the electrode while the electrode transmits ablation energy using a diode coupled to the electrode for conducting heat energy from the electrode in response to current flow from a current source.Type: GrantFiled: May 1, 1995Date of Patent: September 1, 1998Assignee: EP Technologies, Inc.Inventor: David K. Swanson