Abstract: Aspects of the present disclosure provide for a patient warming system having a heating device configured to transfer heat to a patient based on a body heat score that indicates whether the patient is likely to sweat. The heating device includes a heater circuit configured to produce heat, the heater circuit thermally coupled to the patient. The heating device also includes a controller communicatively coupled to the heater circuit. The controller has one or more processors configured to receive one or more physiological indicators of the patient, determine the body heat score from one or more physiological indicators, determine whether the body heat score meets a score threshold, direct the heater circuit to produce a first amount of heat based on whether the body heat score meets a score threshold.

Abstract: Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.

Abstract: Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.

Abstract: An electrosurgical system includes a liquid feeding device for feeding a quantity of liquid to the distal end of a shaft of a bipolar electrosurgical instrument, an impedance measuring device for measuring the impedance of an object arranged at the distal end of the shaft, and a control device that is connected to the impedance measuring device and the liquid feeding device and is configured to control and/or dose the quantity of liquid fed by the liquid feeding device to the distal end of the shaft as a function of the measurement of the impedance measured by the impedance measuring device.

Abstract: A thermal control unit for controlling a patient's temperature includes a fluid outlet for delivering temperature-controlled fluid to a patient, a pump, a heat exchanger, and a controller that automatically pauses thermal treatment of the patient prior the patient reaching a target temperature. During the pause, the controller assesses a reaction of the patient and changes a temperature of the fluid only inside the thermal control unit if the patient is likely to reach the target temperature without further thermal treatment. However, if the patient is unlikely to reach the target temperature without further thermal treatment, the controller restarts the thermal treatment. The controller may pause thermal treatment again prior to reaching the target temperature and assess the patient's reaction. In some embodiments, the controller may selectively include and exclude a fluid reservoir in a circulation channel within the thermal control unit.

Abstract: Aspects of the present disclosure relate to a warming system including a warming device. The warming device includes a clinical garment comprising a body portion adapted to cover a portion of a patient, an inner surface for facing the patient, and an outer surface for facing away from the patient. The body portion includes sleeves sized and positioned for receiving the patient's arms and a torso portion adapted to cover an anterior torso of a patient. A first pneumatic convective device can be disposed adjacent to the inner surface of the clinical garment. The pneumatic convective device can include an opening formed in the clinical garment for admitting a stream of pressurized, warmed air into the first pneumatic convective device. The warming system can also have a second pneumatic convective device in a fully-folded configuration or partially-folded configuration and disposed on a portion of the clinical garment.

Abstract: Systems and methods for adaptively controlling an electrical stimulation device, such as a closed-loop stimulation device, based in part on a Bayesian optimization of the operational parameters of the device are described. An adaptive dual control of the stimulation device can be provided. In a first control loop parameters are extracted from signals recorded from the subject by the stimulation device, and in a second control loop a Bayesian optimization is implemented with a hardware processor and memory to compute updated operational parameters for the stimulation device. As noted, the stimulation device is an electrical stimulation device, and may be a closed-loop stimulation device. Such devices can be used for deep brain stimulation (“DBS”), cardiac resynchronization therapy (“CRT”), and other electrophysiological stimulation applications.

Abstract: A system includes a filter device that has, in serial flow order, an adsorbent bed, a biocide filter, and a particle filter. The adsorbent bed includes adsorbent media that is configured to remove organic compounds from feed water that are capable of forming an adherent layer on a porous surface of a sublimator, and the biocide filter contains a halogen-release material.

Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca/hr-cm-° C.

Abstract: A rapid contrast therapy system can provide cold, heat/hot/warm (hereafter referred to as “hot”), and/or rapid contrast therapy, which involves rapidly alternating between cold therapy and hot therapy. The system can circulate cold or hot fluid, such as water, through a hose, into a therapy wrap, and then back to the fluid reservoirs of the system. The system can utilize a vapor compression system or other chiller technology to cool the cold water reservoir, and immersion heaters can be used to heat the hot water reservoir.

Abstract: The invention is a cooling unit for a heat exchanger integrated in an oxygenator for the purpose of controlling the temperature of blood conveyed in an extracorporeal blood circuit. The cooling unit has a reservoir in which a liquid is stored, a reaction vessel comprises a reactant and which, in conjunction with the liquid, is able to initiate an endothermal reaction. A fluidic access is generated between the reservoir and the reaction vessel. A fluid line extends at least in part inside the reaction vessel which has an inlet line and outlet line connected to be fluid-tight to a hose system of the heat exchanger.

Abstract: Methods, apparatuses and systems are provided for non-invasive delivery of microwave therapy. Microwave energy may be applied to epidermal, dermal and subdermal tissue of a patient to achieve various therapeutic and/or aesthetic results. In one embodiment, the microwave energy is applied to a target tissue via an energy delivery applicator connected to an energy generator. The energy delivery applicator may comprise one or more antennas, including monopole, dipole, slot and/or waveguide antennas (among others) that are used to direct the microwave energy to the target tissue. The energy delivery applicator may also comprise a cooling element for avoiding thermal destruction to non-target tissue and/or a suction device to localize thermal treatment at specific portions of a skin fold.

Abstract: Disclosed is a local cooling anesthesia device for spraying a coolant on a treatment site. The local cooling anesthesia device includes a housing which forms an outward form and from which the coolant is sprayed and a spraying unit installed in the housing to spray the coolant. The device also includes a cooling temperature regulator connected to the spraying unit to apply thermal energy to the sprayed coolant for temperature regulation and a control unit connected to the cooling temperature regulator to control the cooling temperature regulator. The cooling anesthesia device has functions of measuring and regulating the temperature of the coolant, and thus can apply the coolant to the treatment site within a safe temperature range according to the purpose of treatment, thereby enabling a desired treatment purpose such as local anesthesia to be safely and rapidly accomplished without side effects such as cytostasis.

Abstract: The described apparatuses, devices, and mechanisms are configured to measure the temperature of one or more Abreu brain thermal tunnel (ABTT) terminuses. In addition, some embodiments are configured to provide treatment for the diagnosed conditions and diseases.

Abstract: Uterine toner device (UTD) for reducing postpartum hemorrhage includes: a fundal portion including a first end and a second end of the fundal portion, the fundal portion including a conical shaped tip at the first end of the fundal portion; a cervical portion including a first end and a second end of the cervical portion, the first end of the cervical portion coupled to the second end of the fundal portion, where the fundal portion and the cervical portion each include a cylindrical and tubular shaped body, where the body of the cervical portion includes a first plurality of fenestrations; and at least one balloon coupled to a surface of the cervical portion, where when the balloon is inflated, the balloon seals the cervical portion without sealing the first plurality of fenestrations.

Abstract: This disclosure provides a patient support for supporting a patient. The patient support comprises a crib assembly comprising a support material with a cover assembly disposed over the crib assembly. The cover assembly defines a recess and comprising a patient support surface having an outer periphery. The patient support further comprises a connector assembly for connecting the patient support to a fluid source with the connector assembly comprising a connector with a plurality of ports. The assembly defines a three dimensional interior corner adjacent the recess in the cover assembly. The connector assembly is disposed in the recess of the cover assembly such that the plurality of ports of the connector are presented for connection to the fluid source at the three dimensional interior corner and inside the outer periphery of the patient support surface.

Abstract: Afforded is a medical head-cooling cap set that heightens scalp-cooling efficiency and that fitted on to a user's head produces no pressuring feeling nor slips out of place. The cap set is constituted from a head-cooling cap, an inner cap, and an outer cap. Two first belts that are drawn out from either side of the outer-cap opening part and stretch to the exterior are linkable by a first fastener, and after the head has been passed into the opening and the outer cap has been donned, the belts can be fastened neck-area-forward by the fastener; meanwhile, two second belts that extend from alongside the rear part mid-brim and head front brim-ward are linkable by a second clasp, and after the head has been passed into the opening and the outer cap has been donned, the second belts can be fastened around the forehead by the clasp.

Abstract: A medical device that includes a hand piece; a beam fiber; and a beam disperser located at a distal end of the beam fiber through which beam energy is dispersed. The beam disperser includes one face, or a plurality of substantially planar faces through which the beam energy is dispersed.

Abstract: A thermal control unit for controlling a patient's temperature includes a fluid outlet for delivering temperature-controlled fluid to a patient, a pump, a heat exchanger, a controller, and a user interface that displays a graph of patient temperature readings over time. The user interface also displays one or more event icons on the graph at locations corresponding to the time at which events associated with the event icons occurred. In some embodiments, the graph is displayed on a touch screen adapted to allow a user set maximum and minimum permissible temperatures for the fluid by touching areas of the graphs and/or by drawing on certain areas of the graph. An image of a human body having different zones may also be displayed on the user interface along with information pertaining to the thermal therapy being applied to the corresponding zones of the patient's body.

Abstract: A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.

Abstract: A heating apparatus for a vehicle includes: a heat-generating apparatus including a heat-generating portion generating heat and a heat-insulating portion positioned above the heat-generating portion and insulating the heat generated from the heat-generating portion; and a storage apparatus storing the heat-generating apparatus.

Abstract: Systems and methods for managing patient temperature are disclosed. Temperature management systems that are suitable for an out-of-hospital setting are disclosed. Temperature management systems having a low power requirement are disclosed. Temperature management systems that include a disposable, single-use reservoir are disclosed.

Abstract: An apparatus includes a balloon adapted to be placed adjacent a calcified region of a body. The balloon is inflatable with a liquid. The apparatus further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the calcified region adjacent the balloon. The shock wave generator includes a plurality of shock wave sources distributed within the balloon.

Abstract: Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

Abstract: A topper (38) for a bed extends in longitudinal and lateral directions and includes a fluid flowpath (60) for channeling fluid through the topper from an inlet (62) to an outlet (64). The flowpath is configured to distribute the fluid to a preferred target region (50) of the topper. A bed which includes the topper has a blower (72) connected to the topper inlet for supplying air (88) to the flowpath.

Abstract: A surgical drape includes a seal connectable with a selected surface of a body to define a sterile region that includes access to at least two surgical approaches. A sleeve is connected with the seal and a draping is disposed with the body. The sleeve defines a cavity in communication with the region. Surgical instruments, systems and methods are disclosed.

Abstract: A mobile, self-contained cold therapy device having a container including an internal liquid or ice water tank, air and water pumps for driving air and water to a cold therapy pad with internal air and water bladders, wherein the pad is worn on an injured region of a user. The device includes an electronic controller for controlling air and water flow to and from the bladders, and a holder for supporting the container and worn on the user's body for portable, hands-free mobility while receiving cold therapy. Nipples are incorporated into a thermal conduction surface of the pad and reciprocated into the user's injured region by an air bladder to further reduce edema.

Abstract: A portable system for cold therapy with optional heat and compression therapy is disclosed, including a body wrap cooling mechanism, a reservoir, and a control assembly. The body wrap cooling mechanism includes a compressor, a condenser, a fan, and a heat exchanger. The compressor has an air outlet connected to the heat exchanger through a first tube. The heat exchanger is connected to the condenser through a second tube. The condenser is connected to an air inlet of the compressor through a third tube. The first tube is communicated with the second tube, and the second tube is communicated with the third tube. The fan has a working surface facing the condenser. The liquid in the reservoir flows into the first body wrap through a liquid outlet of the reservoir, and liquid in the first body wrap flows into the reservoir through a liquid inlet of the reservoir.

Abstract: Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) a thermoelectric component (TEC) including a first side configured to be operated at a desired temperature and a second side opposite the first side, (ii) a thermally conductive contact member thermally coupled to the TEC, and (iii) a heat transfer system configured to distribute heat from the TEC. The heat transfer system includes a heat transfer structure thermally coupled to the TEC, and a heat exchanger thermally coupled to the heat transfer structure.

Abstract: A thermal control unit supplies temperature controlled fluid to a patient to control the patient's temperature. The thermal control unit includes a fluid outlet, fluid inlet, heat exchanger, pump, patient temperature probe port, user interface, and controller. The controller receives patient temperature readings from the patient temperature probe port and controls a temperature of the circulating fluid in a first manner when no event data is received regarding treatment of the patient. The controller controls a temperature of the circulating fluid in a second and different manner when event data is received. The event data may relate to medication and/or fluid administered to the patient. The different manners include determining a target fluid temperature in using different inputs and/or alarming in different manners. In some cases, the controller pauses the use of the patient temperature readings while continuing to deliver temperature controlled fluid to the patient.

Abstract: A cryoprobe is disclosed comprising a probe shaft made of a low magnetic susceptibility material and an electrical resistance heater comprising counter-wound helical coils located within the probe shaft. The counter-wound helical coils are formed by a single wire counter-wound to form a first set of coils wound in a direction counter to a second set of coils, such that when current is supplied to the electrical resistance heater, a first magnetic field generated by the first set of coils is opposite to a second magnetic field generated by the second set of coils. The electrical resistance heater can heat, thaw, and/or cauterize tissue. The electrical resistance heater can be made of a low magnetic susceptibility material so as to resistively heat tissue concurrently during magnetic resonance imaging (MRI). A method of electrically heating a tissue in conjunction with MRI, and a method of imaging a cryoprobe using MRI is also disclosed.

Abstract: A medical system for monitoring pressure may comprise a medical device with an expandable element, at least one pressure sensor in communication with the expandable element and a control unit. The control unit may include a fluid source in fluid communication with the expandable element and circulation of the fluid within the expandable element may inflate the expandable element. A processing circuitry may be configured to monitor a pressure within the expandable element based on signals received from the at least one pressure sensor for a first period of time and circulation of the fluid within the expandable element for a second period of time.

Abstract: Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

Abstract: An electronic heating/cooling garment includes: a neck part, a collar (neckband), or an underarm part where a Peltier device (31) is placed; and a front body or a back body where a heating medium circulation path (35) and a battery (35) are placed, the battery (35) being configured to supply electric power to a pump (341) and the Peltier device (31). The heating medium circulation path (35) is composed of a flexible thermally conductive material having a tubular shape and holds a heating medium therein in an airtight manner. The heating medium circulation path has a first electrode and a second electrode on its outer surface. The first and second electrodes are configured to supply the electric power from the battery (35) to the Peltier device (31) and the pump (341).

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: A method of treating snoring among two users includes determining that snoring by at least one of the users is occurring, and responsive thereto, either: (a) determining that only one of the at least two users is snoring and responsive thereto generating a signal to produce an anti-snoring motion in an active pillow associated with the one user and generating another signal to produce a distracting motion in another active pillow associated with the other user; or (b) determining that both of the users are snoring and responsive thereto generating signals to produce anti-snoring motions in each of the active pillows.

Abstract: A cryoablation catheter, including a first capsule body, a core tube and a heat insulation part, wherein the first capsule body is mounted at a front end of the core tube, and has a front end area adapted for fitting to myocardial tissue during a cryoablation process and a rear end area exposed to blood; the core tube has a first looping path provided therein which is adapted for a first fluid with low temperature to be filled into or flow out of the first capsule body; the heat insulation part is at least partially fitting to the rear end area, and is adapted for reducing heat exchange efficiency between the first fluid and the blood in an atrium. The cryoablation operating apparatus and the cryoablation equipment thereof can effectively reduce the heat exchange between the cryoablation catheter and the blood during a cryoablation process.

Abstract: Devices, systems for localized delivery of a chemotherapy, hormonal therapy or targeted drug/biologic therapy to a target tissue area of an internal body organ of a patient. A catheter 10 forms a sealed treatment chamber in a natural lumen extending through the target tissue area. Air is purged from the chamber, which is then filled with a liquid drug solution for an adequate treatment session time, solution volume and drug concentration to saturate the target tissue area, thereby providing the treatment. The liquid drug solution may be circulated or recirculated through the chamber or maintained stationary therewithin. The drug may saturate the target tissue area and pass therethrough into the lymphatic system or interstitial space, which may serve as a reservoir of the drug for continued therapeutic treatment after withdrawal of the catheter. The chamber is evacuated at the end of the treatment session.

Abstract: An ablation device and method for pulsed field ablation, the device comprising a catheter including an expandable basket, a set of electrodes formed on the expandable basket, and a pulse generator suitable for generating electric pulses wherein the pulse generator being in electrical connection with the set of electrodes. The expandable basket is formed of a braided mesh of filaments, wherein the filaments are made of nonconductive material, wherein at least portion of the filaments comprises a lumen, or is made by molding, wherein the filaments further include electrodes and conductive wires. The conductive wires at least partially lead inside of the lumen of the filaments, or are overmolded and are electrically connected to the electrodes.

Abstract: A bed system includes microclimate control capabilities for providing quality sleep experience. The bed system can include a microclimate control subsystem configured to supply conditioned air (e.g., heated or cooled air) to a mattress, or draw ambient air from the mattress, to achieve a desired temperature at the top of the mattress. Utilizing supply of conditioned air to provide air at desired temperature to the mattress system, or utilizing air suction to drain heat away from the mattress system, can provide precise microclimate control at the mattress, thereby permitting conformable sleep.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: Systems and methods are described for devices that may include a nasal assembly comprising: a first support member having a first surface configured to substantially conform to a sinistral contour of a nose when the nasal assembly is being worn; a second support member having a second surface configured to follow a dextral contour of the nose when the nasal assembly is being worn; and a heat source electrically coupled to the first support member and the second support member, the heat source being configured to adjust a surface temperature of the first surface and the second surface to cause warming of the sinistral contour of the nose and the dextral contour of the nose to a predefined temperature range.

Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca//hr-cm-° C.

Abstract: A method in which a nerve associated with a spasticity in a limb of a patient may be identified. The cryogenic cooling needle may be inserted through a skin surface. The cryogenic cooling needle may be positioned to a target tissue such that the distal end of the cryogenic cooling needle is proximate to the nerve by bending the needle, wherein the needle has varying stiffness at a proximal portion and a distal portion. A treatment cycle may be delivered to a target tissue proximate to the nerve, the treatment cycle may comprise a cooling phase wherein cooling fluid flows into the lumen so that liquid from the cooling fluid flow vaporizes within the lumen to provide cooling to the nerve so as to treat spasticity.

Abstract: A single integrated cold therapy-compression therapy assembly combines a cold therapy module designed to apply cold therapy in a continuous mode and a compression therapy module designed to apply compression therapy in an intermittent mode to select body parts of a user in accordance with associated integrated therapeutic treatment protocols. The body part selected for therapy is dependent on the particular needs of the user.

Abstract: A system for cooling a circuit component on an electronic device includes a closed-loop cooling circuit and a coolant filling device. The closed-loop cooling circuit includes a coolant block, a first pump and a radiator. The coolant filling device includes a container, a base and a second pump disposed inside the base. The coolant filling device is configured for attachment to the cooling circuit. In some embodiments, when the coolant filling device is attached to the cooling circuit, coolant may be circulated from the coolant filling device to the cooling circuit while the cooling circuit circulates coolant. In further embodiments, when the coolant filling device is attached to the cooling circuit, coolant may be circulated from the coolant filling device to the cooling circuit while the electronic device remains powered on.

Abstract: Disclosed is a headgear-type device for hazardous air quality warning and air quality improvement, wherein the device can collect biometric information of a worker, wired and wireless communications, and information about the quality of outside air around the worker so as to warn the worker of a hazard or improve air quality at the site.

Abstract: The invention pertains to a method for operating a cryocabin arrangement 100 with an open-top cabin 10, a cooling unit 20 and a number of fluid circulation units 30. The method comprises receiving user-specific data comprising at least temperature indications measureable, by a number of sensor devices, at skin surface of the user upon delivery of cooling fluid 201 into the cabin via the cooling unit followed by intake and recirculation of said cooling fluid by fluid circulation units, which further return recirculated cooling fluid 301 inside said cabin, and based on said user-specific data, selectively adjusting distribution of said cooling fluid 201, 301 inside the cabin, in terms of at least speed and/or direction of a fluidic flow, to a predetermined level during an operation cycle.

Abstract: An ablation device and method for pulsed field ablation, the device comprising a catheter including an expandable basket, a set of electrodes formed on the expandable basket, and a pulse generator suitable for generating electric pulses wherein the pulse generator being in electrical connection with the set of electrodes. The expandable basket is formed of a braided mesh of filaments, wherein the filaments are made of nonconductive material, wherein at least portion of the filaments comprises a lumen, wherein the filaments further include electrodes and conductive wires. The conductive wires at least partially lead inside of the lumen of the filaments and are electrically connected to the electrodes.

Abstract: A process and related assemblies for delivering slush through a tube towards a patient. Obtaining an elongated container partially filled with slush with a port end that has a first port and a second port. Placing the first port in fluid communication with tubing for delivery of slush towards the patient. Placing the second port in fluid communication with a source of gas which may be air. Subjecting the elongated container to automated repetitive movements so that the slush in the partially filled elongated container moves against interior surfaces within the elongated container. Ideally, two different forms of repetitive motion are used to impose complex movement upon the slush within the elongated container. Applying a pressure gradient to cause slush to flow out of the first port towards the patient. The elongated container may be made from a slush bottle with a reversibly engaged cap with the two ports.