Internally Applied Patents (Class 607/105)
  • Patent number: 10726742
    Abstract: Systems and methods are described herein for producing a model of a biological tissue, comprising a primary elastic material formed in the shape of an organ, and a secondary stiffener material embedded in the primary elastic material, wherein the secondary stiffener material is formed into a metamaterial design that increases the elastic modulus of the model in at least one predetermined direction. Models in accordance with embodiments mimic both the shape and mechanical properties of the organ they depict.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: July 28, 2020
    Assignee: Georgia Tech Research Corporation
    Inventors: Kan Wang, Zhen Qian, Chun Zhang, Changsheng Wu, Ben Wang, Mani A. Vannan
  • Patent number: 10682171
    Abstract: The present invention provides a medical device that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: June 16, 2020
    Assignee: Medtronic CryoCath LP
    Inventors: Dan Wittenberger, Marwan Abboud, Ioana Deac
  • Patent number: 10661060
    Abstract: A method is disclosed for selective inflation of an inflatable body, such as a balloon, received through an oral cavity and into the esophagus of a patient. The inflatable body is operably coupled to a pressurized fluid source. The inflatable body has a relatively flexible portion and a relatively inflexible portion. When pressurized fluid is delivered to the body to inflate the body, the flexible portion expands more than the inflexible portion, resulting in asymmetrical expansion and movement of the esophagus away from the ablation site to avoid accidental injury while performing a procedure on the patient's left atrium. This movement may be opposite from or directly away from the heart or, alternatively, may be sideways relative to the heart to a location in which the esophagus is interposed between the ablation site and the phrenic nerve.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: May 26, 2020
    Assignee: Niazi Licensing Corporation
    Inventor: Imran K. Niazi
  • Patent number: 10639191
    Abstract: Closed loop heat exchange catheters having bi-directional flow heat exchange regions and their methods of manufacture and use. The heat exchange region may be formed of expandable or non-expandable tubular conduit(s) that are configured in a series of loops or coiled configuration defining a supply flow path and a return flow path through which heat exchange medium is circulated. The individual loops of convolutions of the coiled configuration may be the same or different size. In some embodiments, the tubular conduit(s) may be passed through generally transverse bore holes formed in a catheter shaft so that the loops or convolutions of protrude from the catheter shaft.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: May 5, 2020
    Assignee: Zoll Circulation, Inc.
    Inventor: Jeremy Thomas Dabrowiak
  • Patent number: 10596029
    Abstract: An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: March 24, 2020
    Assignee: Zoll Circulation, Inc.
    Inventors: Alex L. Lim, Masouneh Mafi, Venkata Vishnu Gurukula, Richard A. Helkowski
  • Patent number: 10568760
    Abstract: A method for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: February 25, 2020
    Assignee: Zoll Circulation, Inc.
    Inventor: Norman A. Paradis
  • Patent number: 10569064
    Abstract: Systems and methods for systems and methods for focal cooling of the brain and spinal cord are disclosed. Some embodiments may be directed to a neuroprotection system that includes a cerebrospinal fluid processing platform. Embodiments may provide rapid and selective spinal cord hypothermia and drainage. Embodiments may be tailored to selective spinal cord cooling, pressure monitoring and automated drainage. Embodiments may enable local hypothermic neuroprotection, limit the stress of systemic cooling, minimize secondary neuronal damage and achieve maximal neuroprotection while at the same time improving workflow as a result of automated drainage. Embodiments may include a multi-lumen catheter, a drainage collection reservoir bag, a pump to circulate coolant, sensor hardware and controllers to modulate the flow of a heat transfer fluid for cooling to modulate therapeutic hypothermia and re-warming. Certain embodiments may include extracorporeal cooling of cerebrospinal fluid (CSF).
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 25, 2020
    Assignee: MINNETRONIX, INC.
    Inventors: Abhi Vase, Don W. E. Evans
  • Patent number: 10561528
    Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: February 18, 2020
    Assignee: Zoll Circulation, Inc.
    Inventors: James D Mazzone, Masoumeh Mafi, Alex L Lim, Jack I Irwin, Dung A Nguyen
  • Patent number: 10548763
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 4, 2020
    Assignee: Zoll Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 10512735
    Abstract: A fluid warming device for warming fluids and delivering the fluids to a patient comprises an electrical heating component, a temperature sensor, and a control unit. The electrical heating component warms fluid passing through a fluid-carrying tube and may be positioned along the fluid-carrying tube at a desired location or embedded in the fluid-carrying tube while the control unit is positioned such that the display and user inputs are accessible to a caregiver. The control unit activates the electrical heating component until the fluid-carrying tube is warmed to a desired temperature within a Thermal Neutral Zone (TNZ) as sensed by the temperature sensor.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: December 24, 2019
    Assignee: Neonatal Product Group, Inc.
    Inventors: Scott Norman, Mark Petheram, Anthony Hash
  • Patent number: 10441707
    Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: October 15, 2019
    Assignee: MEDIVANCE INCORPORATED
    Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
  • Patent number: 10434008
    Abstract: The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.
    Type: Grant
    Filed: May 15, 2011
    Date of Patent: October 8, 2019
    Inventor: Rohit Khanna
  • Patent number: 10363381
    Abstract: Apparatus for warming medical infusion fluids includes a heat pipe (12) warmed by an electrical heater (17) at one end. A replaceable fluid flow path (20) of helical configuration extends along the heat pipe (12) and is formed between an inner, thermally-conductive sleeve (21) with a helical profile and an outer insulative sleeve (26). An inlet (3) to the flow path (20) is located adjacent the heater (17), the outlet (4) being at the opposite end of the heat pipe (12). The inlet (3) is connected to a suspended saline bag (1) and the outlet (4) connects via tubing (5) to a catheter (6) inserted in a blood vessel. A temperature sensor (18) in the outlet tubing (5) provides a feedback output to a control unit (11) that controls operation of the heater (17) to maintain a stable temperature.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: July 30, 2019
    Assignee: Smiths Medical International Limited
    Inventor: Fredrick M Richards
  • Patent number: 10363364
    Abstract: The present application provides systems that include a controller, and an insertion device with at least one temperatures sensor thereon and a pump coupled to the controller. The insertion device provides temperature measurement(s) at/of a subject's organ to the controller and the controller varies an infusate flow rate to induce temperature changes in at least a portion of the subject's organ and stores the temperature measurements during perfusion induced temperature changes on a memory device. The controller may estimate at least one hemodynamic characteristic of at least a portion of the subject's organ based on the temperature measurements obtained during perfusion induced temperature changes.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: July 30, 2019
    Assignee: Hybernia Medical LLC
    Inventors: John Pile-Spellman, Jae H. Choi
  • Patent number: 10300243
    Abstract: A catheter apparatus includes a replaceable module, a main body portion and a sensing module. The main body portion includes a tube, a urine guide opening and an elastic unit. The replaceable module includes a control unit. A first terminal of the tube is coupled to the replaceable module and a second terminal of the tube is inserted into the bladder. The urine guide opening is disposed at the second terminal of the tube and used to guide urine into the tube when the second terminal of the tube is inserted into the bladder. The elastic unit is disposed at the second terminal of the tube and coupled to the control unit. The sensing module is coupled to the control unit and used to sense whether the second terminal of the tube is inserted to the correct position in the bladder and transmit sensing result to the control unit.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: May 28, 2019
    Assignee: CRYSTALVUE MEDICAL CORPORATION
    Inventors: William Wang, Meng-Shin Yen, Chung-Cheng Chou, Chung-Ping Chuang
  • Patent number: 10271889
    Abstract: An apparatus for cooling certain tissues in the vicinity of diseased or other tissue undergoing thermal treatment is disclosed. The present apparatus is configured and designed to have certain physical characteristics, e.g., certain acoustic and imaging responses. In some embodiments the present apparatus is compatible with magnetic resonance imaging (MRI) environments used in conjunction with the thermal treatment, or other imaging environments. In some embodiments the present apparatus is detectable by said MRI and is within the imaging field of view (FOV) but causes few or no imaging artifacts. Additionally, the present apparatus does not substantially interfere with the thermal treatment, e.g., ultrasonic therapy, which can proceed to heat the targeted volume of tissue while protective cooling of tissues near the diseased tissue by the present apparatus takes place.
    Type: Grant
    Filed: June 27, 2010
    Date of Patent: April 30, 2019
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Michael J. Bronskill, Rajiv Chopra
  • Patent number: 10265460
    Abstract: The present disclosure describes for at least two zones of selective thermal therapy of the body. Three-port extracorporeal circuits are described that can be used to establish at least two zones of selective thermal therapy of the body. The example three-port extracorporeal circuit includes a branching section that provides for setting the temperature of blood injected into two different portions of the body at differing temperature levels, to provide at least two zones of selective thermal therapy.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: April 23, 2019
    Assignee: Asia Pacific Medical Technology Development Company, Ltd.
    Inventor: John R. Gilbert
  • Patent number: 10111669
    Abstract: A system for deploying and selectively inflating a thoracic aortic balloon at a desired location within the thoracic aorta for resuscitative aortic occlusion, inferior to the left subclavian artery, without the aid of fluoroscopy is described. Using CT imaging data, a distance between readily identifiable and consistently located external landmarks of torso extent is measured. Next, using the same data, a second distance from the femoral artery to a desired aortic occlusion location inferior to the left subclavian artery is determined. A correlation between the external measure of torso extent and the desired intra-arterial (i.e. endovascular) distance within the torso is made. Using a nomogram, a calibrated endovascular resuscitative thoracic aortic occlusion system can be positioned to this desired location on any injured individual with end-stage shock and impending cardiovascular collapse or death without the aid of fluoroscopy for delivery or balloon inflation.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: October 30, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Jonathan L. Eliason, Todd E. Rasmussen
  • Patent number: 10085879
    Abstract: A heat treatment device with a handle portion, a tip portion, a power source, and a heating element. The tip portion is heatable to a desired temperature and can be positioned against an affected area for therapeutic treatment. The device can also have control circuitry that can adjust a current flowing to the heating element to regulate the treatment temperature.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: October 2, 2018
    Assignee: EMPIRE TECHNOLOGY DEVELOPMENT, LLC
    Inventor: Kevin Anthony Pezzi
  • Patent number: 10022265
    Abstract: An enclosure or plenum that supports a looped pump tube is hingedly connected to a framed thin-walled heat exchange bag through which working fluid from an intravascular heat exchange catheter flows. The frame with bag can be inserted between cold plates to exchange heat with the working fluid flowing through the bag. With the framed bag between the plates, the looped pump tube from the enclosure or plenum is receivable in the raceway of a peristaltic pump, which pumps working fluid through the system.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: July 17, 2018
    Assignee: Zoll Circulation, Inc.
    Inventors: Christo Petrov Pamichev, Jeremy Thomas Dabrowiak
  • Patent number: 9943365
    Abstract: A renal nerve ablation device may include an elongate tubular member having a distal region. An expandable member may be coupled to the distal region. An electrode support may be coupled to the distal region of the elongate tubular member and extend over a body of the expandable member. The electrode support may be free of connection to the body of the expandable member. One or more electrodes may be coupled to the electrode support.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: April 17, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Patrick A. Haverkost, Joel N. Groff, Martin R. Willard, Timothy A. Ostroot, Derek C. Sutermeister, Cass A. Hanson, Daniel T. Quillin, Joel R. Munsinger
  • Patent number: 9936996
    Abstract: A medical device including elongate probe defining proximal and distal ends and a thermally-transmissive region at its distal end, the elongate probe including a first fluid supply line in fluid communication with the thermally-transmissive region. A second fluid supply line is provided in fluid communication with the thermally-transmissive region, the second fluid supply line being connected to the elongate probe separately from the first fluid supply line. An exhaust line in fluid communication with the first and second fluid supply lines.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: April 10, 2018
    Assignee: Medtronic ATS Medical, Inc.
    Inventor: Andrew K. Zachman
  • Patent number: 9937329
    Abstract: A device and system are disclosed for selective inflation of an inflatable body, such as a balloon, received through an oral cavity and into the esophagus of a patient. The inflatable body is operably coupled to a pressurized fluid source. The inflatable body has a relatively flexible portion and a relatively inflexible portion. When pressurized fluid is delivered to the body to inflate the body, the flexible portion expands more than the inflexible portion, resulting in asymmetrical expansion and movement of the esophagus away from the ablation site to avoid accidental injury while performing a procedure on the patient's left atrium. This movement may be opposite from or directly away from the heart or, alternatively, may be sideways relative to the heart to a location in which the esophagus is interposed between the ablation site and the phrenic nerve.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 10, 2018
    Assignee: Niazi Licensing Corporation
    Inventor: Imran K. Niazi
  • Patent number: 9918872
    Abstract: A system for treating uterine atony, and promoting contraction of a uterus includes a heat transference article having a chilled surface in contact with an inner or outer surface of the uterus for a length of time sufficient to promote contraction while avoiding tissue damage. A heat transference medium such as a chilled saline solution, or cold gel is introduced to the article by injection, pre-filling, immersion or other suitable means, and is circulating or non-circulating.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: March 20, 2018
    Inventors: James Daniel Crowson, Jack Alfred Stecher
  • Patent number: 9895109
    Abstract: A monitoring device (7) operates an input block (30) to acquire a pressure signal from a pressure sensor (6a-6c) in an apparatus for extracorporeal blood processing connected to the vascular system of the subject. A processing block (34) repeatedly processes the pressure signal for generation of a time-sequence of parameter values indicative of pressure pulsations originating from heartbeats in the subject, and an evaluation block (35) evaluates the parameter values for detection of cardiac arrest and, if cardiac arrest is detected, generates a dedicated alarm signal.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 20, 2018
    Assignee: Gambro Lundia AB
    Inventors: Per Hansson, Bo Olde, Kristian Solem, Jan Sternby
  • Patent number: 9888956
    Abstract: The present disclosure relates to devices and methods for the cooling of ablation technology used to treat tissue. The devices and methods disclosed herein utilize a multiple use generator assembly which includes an integrated cooling system, and a disposable, single-use subassembly which includes a disposable pump head and ablation device.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: February 13, 2018
    Inventors: Jeffrey Model, Robert Rioux
  • Patent number: 9848951
    Abstract: The ablation systems, ablation probes, and corresponding methods according to the present disclosure reduce or eliminate energy radiating from an ablation probe into the environment. Some ablation probes include a retractable sheath that shields at least the radiating portion of the ablation probe. The retractable sheath and/or the ablation probe may include conduits through which a fluid may flow to shield the radiating portion and to drive the retractable sheath to an extended state. Other ablation probes include apertures defined in the probe walls through which the fluid can flow to expand a balloon surrounding the radiating portion. Yet other ablation probes include a thermal indicator to indicate the temperature of the ablation probe to a user. The ablation systems include fluid circuits and associated mechanical controls for varying the contents and/or flow rate of the fluid provided to the radiating portion of the ablation probe.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: December 26, 2017
    Assignee: COVIDIEN LP
    Inventor: William O. Reid, Jr.
  • Patent number: 9801756
    Abstract: A system includes a heat exchange catheter line assembly configured to convey working fluid circulating to and from at least one heat exchange element on an intravascular heat exchange catheter. The system also includes a heat exchange system that itself includes a processor and is configured for fluidly communicating with the heat exchange catheter line assembly to exchange heat with the working fluid. A near field communication (NFC) member associated with the heat exchange system and an NFC element associated with the heat exchange catheter line assembly are also included. The NFC member is configured to provide the processor with a signal representative of whether the NFC member detects the NFC element.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: October 31, 2017
    Assignee: ZOLL CIRCULATION, INC.
    Inventors: Jeremy T. Dabrowiak, James Palazzolo, Richard A. Helkowski
  • Patent number: 9717625
    Abstract: A catheter has a hollow conduit through which working fluid from a heat exchange system flows. The conduit in turn is configured to extend along a longitudinal central axis in a continuously varying non-constant azimuthal orientation so that it defines a non-round enclosed passageway through which blood can flow to exchange heat through a wall of the conduit with the working fluid flowing within the conduit.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: August 1, 2017
    Assignee: Zoll Circulation, Inc.
    Inventor: Alex L. Lim
  • Patent number: 9690362
    Abstract: The present disclosure provides a surgical instrument control circuit. The control circuit includes a primary processor, a safety processor in signal communication with the primary processor, the safety processor, and a segmented circuit. The segmented circuit includes a plurality of circuit segments in signal communication with the primary processor. The plurality of circuit segments is configured to control one or more operations of the surgical instrument. The safety processor is configured to monitor one or more parameters of the plurality of circuit segments.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: June 27, 2017
    Assignee: Ethicon LLC
    Inventors: Richard L. Leimbach, Shane R. Adams, Mark D. Overmyer, Brett E. Swensgard, Thomas W. Lytle, IV, Frederick E. Shelton, IV, Kevin L. Houser
  • Patent number: 9642741
    Abstract: Surgical cooling may be implemented by various systems, processes, and techniques. In certain implementations, a surgical cooling device includes a shaft, a cooling assembly, and a mechanical control system. The shaft includes a pair of axial cooling channels extending through its interior. The cooling assembly includes a pair of arms pivotally attached to the shaft and a foldable thermal exchanger coupled to the pair of arms and fluidly coupled to the pair of axial cooling channels. The mechanical control system is adapted to unfold the cooling assembly from a closed position to an open position to allow a coolant to flow through a first of the pair of axial cooling channels, through one or more thermal exchange channels, and out a second of the pair of cooling channels.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: May 9, 2017
    Inventors: Yusheng Feng, Dipen J. Parekh, Richard Dashan Canty, Luis Alberto Davila, Justin Alexander Long
  • Patent number: 9622908
    Abstract: A device is provided for cooling intra nasally the brain of a patient, in particular of a patient suffering from cardiovascular emergency. The device comprises a pressurized gas container for containing a gas or a mixture of gases, and at least one cannula with a lumen, a proximal opening and at least one distal opening. The cannula is for introduction into the patient's nasopharynx. Upon operation, gas expands adiabatically upon exiting from the at least one cannula, thereby cools and provides a coolant effect on the nasopharynx and inside the nasal cavity.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: April 18, 2017
    Assignee: Schiller Medical S.A.S.
    Inventor: Guy Fontaine
  • Patent number: 9622909
    Abstract: Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: April 18, 2017
    Assignee: Advanced Cooling Therapy, Inc.
    Inventors: Erik Kulstad, Hugh Patrick Caherty
  • Patent number: 9579150
    Abstract: A surgical ablation system features a source of ablation energy, a handle adapted to operably couple to the source of ablation energy, and an ablation probe adapted to operably couple to the handle. The handle includes a housing having a proximal end and a distal end, a hub included within the housing having a plenum defined therein, and a proximal feedline in fluid communication at a proximal end thereof with the plenum and joined at a distal end thereof to a first coupling member. The ablation probe includes a probe hypotube shaft having a proximal end and a distal end, a second coupling member disposed at a proximal end of the probe hypotube shaft adapted to operably couple with the first coupling member, a distal tip adapted to penetrate tissue. Ablation energy is deliverable by the ablation probe when the source of ablation energy is operably coupled to the handle and the handle is operably coupled to the ablation probe.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 28, 2017
    Assignee: COVIDIEN LP
    Inventor: Arnold V. DeCarlo
  • Patent number: 9517160
    Abstract: A kit for cooling the blood in the carotid arteries includes a cervical immobilization collar and a cooling element. The cooling element may include a body-facing panel attached on a body-facing surface to a lining layer, an outward-facing panel, and cooling material disposed between the body-facing panel and the outward facing panel. The cooling material may comprise urea and Carbamakool™ in an amount sufficient to produce a temperature of 20° F. to 35° F. within a minute of activation when measured on the body-facing surface of the body-facing panel.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: December 13, 2016
    Assignee: CRYOTHERMIC SYSTEMS, INC.
    Inventors: Aqeel A. Sandhu, Scott Raybuck, Brian J. Seitz
  • Patent number: 9375273
    Abstract: A microwave ablation system includes a generator operable to output energy and an ablation probe coupled to the generator that delivers the energy to a tissue region. The ablation system also includes a controller operable to control the generator and at least one sensor coupled to the ablation probe and the controller that detects an operating parameter of the ablation probe. The controller performs a system check by ramping up an energy output of the generator from a low energy level to a high energy level and monitors an output from the sensor at predetermined intervals of time during the system check to determine an abnormal state. The controller controls the generator to cease the energy output when the controller determines an abnormal state.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: June 28, 2016
    Assignee: Covidien LP
    Inventors: Joseph D. Brannan, Jeffrey L. Jensen, Darion Peterson, Kyle R. Rick
  • Patent number: 9364165
    Abstract: The present invention relates to an apparatus for moving a target element which comprises a magnetic material and an active agent, through an object, placing the target element at a predetermined position within the object and activating the active agent.
    Type: Grant
    Filed: September 6, 2010
    Date of Patent: June 14, 2016
    Assignee: Koninklijke Philips N.V.
    Inventor: Bernhard Gleich
  • Patent number: 9326890
    Abstract: Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: May 3, 2016
    Assignee: Advanced Cooling Therapy, Inc.
    Inventors: Erik Kulstad, Hugh Patrick Caherty
  • Patent number: 9320644
    Abstract: Methods, systems, and devices are disclosed for providing selective and non-selective cooling and warming of a patient. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway, aerodigestive tract, and/or more generalized cooling by irrigating the esophagus and/or stomach.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: April 26, 2016
    Assignee: NEUROSAVE, INC.
    Inventors: Thomas Kreck, Seth Rodgers, Ian Sas
  • Patent number: 9289257
    Abstract: Methods, systems and devices for endometrial ablation. In accordance with a method, a working end of an RF ablation device is positioned in a patient uterus to contact endometrial tissue, the working end comprising a dielectric wall capable of non-expanded and expanded shapes. An indicator mechanism is operatively coupled to the wall and configured to indicate non-expanded and expanded shapes of the wall.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: March 22, 2016
    Assignee: MINERVA SURGICAL, INC.
    Inventors: Akos Toth, Ronald Hundertmark
  • Patent number: 9238133
    Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more passive cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more passive cooling elements is configured to be implantable, and wherein the one or more passive cooling elements includes a first portion configured to be in association with the one or more tissues to be cooled, and a second portion configured to be placed in association with one or more tissues adjacent to an external epidermal tissue of the vertebrate subject.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: January 19, 2016
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Eric C. Leuthardt, Stephen L. Malaska, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 9186486
    Abstract: Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: November 17, 2015
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jan Weber, John M. Hokanson, John J. Chen
  • Patent number: 9138287
    Abstract: Devices and methods for efficiently and reproducibly heating fluid for use in fluid enhanced ablation are disclosed herein. In one embodiment, an ablation device is provided having an elongate body, at least one wire extending through an inner lumen of the elongate body, and at least one spacer disposed within the inner lumen. The at least one wire extends through the at least one spacer such that the at least one spacer is effective to maintain an adjacent portion of the at least one wire in a substantially fixed geometric relationship with the inner lumen, thereby preventing electrical shorts and providing for the consistent and uniform heating of fluid flowing through the inner lumen of the elongate body.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: September 22, 2015
    Assignee: Thermedical, Inc.
    Inventors: Michael G. Curley, Fredrick J. Kim
  • Patent number: 9138344
    Abstract: A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: September 22, 2015
    Assignee: Zoll Circulation, Inc.
    Inventor: Paul M. Stull
  • Patent number: 9131853
    Abstract: The present invention resides in one aspect in a device for monitoring luminal esophageal temperatures in a patient. The device includes a probe adapted to be inserted into an esophagus of the patient. The probe extends between a proximal end and a distal end. A first temperature sensor and a second temperature sensor are coupled to the probe. An electrode is also coupled to the probe. The second temperature sensor is displaced from the first temperature sensor along a longitudinal axis of the probe. A controller processes information received by the electrodes and the temperature sensors. The controller generates a live and continuously updating three dimensional anatomic map and three dimensional thermal map of the esophagus based at least in part on the information received from the temperature sensors and the electrodes. The thermal map and the anatomic map are displayed on a video monitor.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: September 15, 2015
    Inventor: Joseph Tiano
  • Patent number: 9128361
    Abstract: In at least one embodiment of the disclosure, a projector comprises an optical element holding member that allows a flow of a cooling liquid therein. A plurality of liquid circulation members connect the optical element holding member and a liquid pumping unit and to define a flow channel of the cooling liquid. A heat-receiving jacket is disposed in the flow channel and has a plurality of flow channels. A thermoelectric conversion element having a heat-absorbing surface is connected to the heat-receiving jacket and a heat-radiating surface is connected to a heat transfer member. A supporting member fixes the heat-receiving jacket and the heat transfer member. A baffle member defines an internal space with the supporting member and houses the heat transfer member in the internal space. A cooling fan provides cooling air to the heat transfer member disposed in the internal space.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: September 8, 2015
    Assignee: Seiko Epson Corporation
    Inventors: Yoshiyuki Yanagisawa, Yasunaga Momose
  • Patent number: 9074946
    Abstract: A thermometer with protective tube inner part for insertion into a protective tube, especially a protective tube of a thermometer, wherein the protective tube inner part serves for arranging conductor elements, and wherein the protective tube inner part is matched to the shape of the inside of the protective tube in the region of a closed, protective tube end, and wherein the protective tube inner part serves to arrange the conductor elements on the side of the protective tube inner part facing the protective tube in the installed state.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 7, 2015
    Assignee: ENDRESS + HAUSER WETZER GMBH + CO. KG
    Inventors: Dieter Schmidt, Peter Seefeld, Alfred Umkehrer, Wilfried Meissner, Helmut Kalteis
  • Patent number: 9056004
    Abstract: Methods and apparatus for treating or deterring injuries to or disorders of the brain or spinal cord of a subject. A heat exchange catheter device is inserted into the subject's body and used to cause heating or cooling the subject's cerebrospinal fluid. In some embodiments, the heat exchanger may be positioned within the subject's vasculature so as to heat or cool the flowing blood, thereby resulting in heating or cooling of the cerebrobpinal fluid.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: June 16, 2015
    Assignee: ZOLL Circulation, Inc.
    Inventors: Robert Ginsburg, Timothy R. Machold, Michael T. Dineen
  • Patent number: 9050076
    Abstract: This invention relates to the treatment of a patient's lung, for example, a lung exhibiting chronic obstructive pulmonary disease (COPD) and in particular to methods and devices for affecting lung volume reduction, preferably for achieving acute or immediate lung volume reduction following treatment. The lung volume reduction is effected by delivering a condensable vapor at a temperature above body temperature to the desired regions of the patient's lung to damage tissue therein. Blood flow and air flow to the damaged tissue region is essentially terminated, rendering the target region non-functional. Alternative energy sources may be used to effect the thermal damage to the lung tissue.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: June 9, 2015
    Assignee: Uptake Medical Corp.
    Inventors: Robert L. Barry, Brian Cran, Dean Corcoran, Sheldon K. Lee
  • Patent number: 9050072
    Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: June 9, 2015
    Assignee: Sanarus Technologies, Inc.
    Inventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane