Internal Application Patents (Class 607/113)
  • Patent number: 10111704
    Abstract: Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: October 30, 2018
    Assignee: Relievant Medsystems, Inc.
    Inventors: Richard Pellegrino, Paula Papineau, John S. Crombie, Samit Patel, Thomas Ryan
  • Patent number: 9820808
    Abstract: A method is disclosed for the treatment of a thoracic region of a patient's body. Embodiments of the method comprise positioning an energy delivery portion of an electrosurgical device to face a segment of a thoracic vertebra at a distance from the segment; and cooling the energy delivery portion and delivering energy through the energy delivery portion.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 21, 2017
    Assignee: Avent, Inc.
    Inventors: Amy Lefler, Neil Godara, Robert Harrison
  • Patent number: 9669214
    Abstract: An electrical stimulation device provides stimulation of a person's claustrum and piriform cortex to treat seizures for persons having epilepsy, and to improve consciousness in individuals with disorders of consciousness such as coma. The stimulation device includes a stimulator that generates a stimulation signal, and one or more electrodes located near the target brain regions (Claustrum/piriform cortex). The electrode receives the stimulation signal from said stimulator and imparts the stimulation signal to the target brain regions.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: June 6, 2017
    Assignee: The George Washington University
    Inventor: Mohamad Z. Koubeissi
  • Patent number: 9592150
    Abstract: This invention is directed to a medical device and a method of treating mammals, especially humans, to alleviate the symptoms, including pain, of several conditions and symptoms, including hemorrhoids, tissue inflammation and/or yeast infections, and open, draining wounds or incisions.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: March 14, 2017
    Inventor: William J. McNulty, Jr.
  • Patent number: 9301871
    Abstract: Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: April 5, 2016
    Assignee: Advanced Cooling Therapy, Inc.
    Inventors: Erik Kulstad, Hugh Patrick Caherty
  • Patent number: 9283112
    Abstract: A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: March 15, 2016
    Assignee: Zoll Circulation, Inc.
    Inventors: Alex L. Lim, Venkata Vishnu Gurukula, Jeremy T. Dabrowiak, Richard A. Helkowski
  • Patent number: 9283110
    Abstract: A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: March 15, 2016
    Assignee: Zoll Circulation, Inc.
    Inventors: Alex L. Lim, Venkata Vishnu Gurukula, Jeremy T. Dabrowiak, Richard A. Helkowski
  • Publication number: 20150141951
    Abstract: In one aspect, the present disclosure is directed to a method for treating a bladder within a body of a subject, including inserting one or more heaters into the bladder wall of a subject, and selectively heating the one or more heaters by a remote device.
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Inventors: Sandra NAGALE, Mark W. BODEN, Timothy Paul HARRAH, Michael C. LARSON
  • Patent number: 9028538
    Abstract: Disclosed are vertebroplasty methods that include cauterizing an inner cavity of a vertebra of a mammal, such as a human, and injecting bone cement into the vertebra. Systems and kits for performing such methods are also disclosed.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: May 12, 2015
    Assignee: Globus Medical, Inc.
    Inventors: David C. Paul, Sean Suh, Mark Weiman, Jody L. Seifert
  • Patent number: 9031667
    Abstract: A method and device for inducing anaesthesia in mammals by the application of RF energy to create hyperthermia derived neural anaesthesia. An RF generator drives a plurality of electrodes placed in tissue surrounding the target nerve fiber to desiccate the desired length of nerve fiber to be desiccated in a single deployment. The device allows high-speed selection/de-selection of bipolar electrode pairs or sets under continuous RF excitation. Activation of electrode pairs is adapted in response to sensed current density and temperature (by electrodes not in the current discharge activation phase) in order to create lesions of complex and well defined shape necessary for the production of hyperthermia derived neural anaesthesia.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: May 12, 2015
    Assignee: InterventionTechnology Pty Ltd
    Inventor: Donald V. Williams
  • Patent number: 9023031
    Abstract: The invention provides improved methods for modifying collagenous tissues, particularly for treating urinary incontinence in a noninvasive manner. The methods typically include inserting a probe into a patient's urethra, transmitting electromagnetic energy from the probe to a collagneous target tissue, and cooling the tissue in the vicinity of the probe. The probe may include an expandable element at or near the distal end that is configured to expand within the patient's bladder. The expandable element may anchor the probe before or during treatment.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: May 5, 2015
    Assignee: Verathon Inc.
    Inventors: Frank W. Ingle, Garry L. Carter, Robert J. Laird, John Claude, Paul Do, Brian J. Mosel
  • Publication number: 20150119849
    Abstract: Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure.
    Type: Application
    Filed: December 21, 2011
    Publication date: April 30, 2015
    Applicants: The General Hospital Corporation D/B/A Massachusetts Gerneral Hospital, ETHICON ENDO-SURGERY, INC.
    Inventors: Taylor W. Aronhalt, Lee M. Kaplan, Nicholas Stylopoulos, Jason L. Harris, Dwight D. Henninger, James W. Voegele, Mark S. Ortiz
  • Patent number: 9011510
    Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more cooling elements is configured to be implantable, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: April 21, 2015
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Eric C. Leuthardt, Stephen L. Malaska, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 9008793
    Abstract: A apparatus for performing tissue modification procedures on a patient's body can include a device, which can be adapted for connection to at least two electrodes, where temperature sensors can be incorporated into tip portions of said electrodes, a high frequency generator, which can be operatively associated with said device, wherein said generator can deliver non-simultaneously a high frequency signal output to each of said electrodes, and a feedback control circuit, which can be configured to regulate the signal output delivery to each of said electrodes so it can maintain a user settable temperature at tip portion of said electrodes when the electrodes can be in contact with the patient's body.
    Type: Grant
    Filed: October 15, 2007
    Date of Patent: April 14, 2015
    Assignee: Chenes LLC
    Inventors: Eric R. Cosman, Sr., Eric R. Cosman, Jr.
  • Patent number: 8968378
    Abstract: Closed loop heat exchange catheter systems and methods for preparing and using such systems wherein a reservoir or fluid bag is connected to the catheter system and used for at least priming of the system with a heat exchange fluid.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: March 3, 2015
    Assignee: ZOLL Circulation, Inc.
    Inventors: Robert Ginsburg, Timothy R. Machold, Michael T. Dineen, Arlene S. Ginsburg
  • Patent number: 8968377
    Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: March 3, 2015
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Eric C. Leuthardt, Stephen L. Malaska, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Publication number: 20150045858
    Abstract: The present invention relates to a brain cooling device for a craniotomy patient, and more specifically, to a brain cooling device for a craniotomy for cooling the brain so as to prevent damage to the brain after a brain surgery. To this end, the present invention provides the brain cooling device for a craniotomy patient comprising: a cooling portion which is buried in such a manner to come into contact with the brain or the dura mater; and one withdrawal tube, which is one end of the cooling portion that is exposed to the exterior, wherein the withdrawal tube is exposed to the exterior by penetrating through the scalp and the cranium.
    Type: Application
    Filed: February 6, 2013
    Publication date: February 12, 2015
    Applicant: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventors: Jae Chan Park, Kyoung Ho Suk, Hyung Soo Han, Dong Ick Rhee
  • Publication number: 20150045783
    Abstract: Methods of using hardware (e.g., bone screws, anchors or other devices) previously inserted within the body to facilitate energy delivery are disclosed. The energy delivery (e.g., thermal energy) may be used for neuromodulation (such as stimulation or denervation), tissue heating and ablation, curing, and other applications in the spine and non-spine orthopedic locations.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 12, 2015
    Inventor: Avram Allan Edidin
  • Patent number: 8944071
    Abstract: Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung are disclosed. The damaging of lung cells, damaging tissue, causing trauma, and/or destroying smooth muscle tone with the apparatus may be accomplished via any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: February 3, 2015
    Assignee: Asthmatx, Inc.
    Inventors: Bryan Loomas, Michael D. Laufer, David P. Thompson
  • Patent number: 8936631
    Abstract: A method of performing therapy on tissue using a medical apparatus. The apparatus includes a shaft configured for insertion into a hollow anatomical structure (HAS) and has a tissue sensor and a therapeutic energy application device both located on the shaft. The method comprises: receiving electrical power at a first power level and directing the first-level power to the tissue sensor and not to the therapeutic energy application device, thereby enabling tissue sensing with the tissue sensor; receiving electrical power at a second power level higher than the first-level power; and, in response to receipt of the second-level power, directing the second-level power to the therapeutic energy application device, thereby enabling performance of therapy on the tissue with the therapeutic energy application device. Additional methods and apparatus are disclosed as well.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: January 20, 2015
    Assignee: Covidien LP
    Inventors: Hoa D. Nguyen, Arthur W. Zikorus, Stephen W. Lee
  • Publication number: 20150005680
    Abstract: Methods and devices to treat discogenic lumbar back pain are disclosed. Electrodes are implanted within the anterior epidural space of the patient. A pulse generator that is connected to the electrodes delivers electrical impulses to sympathetic nerves located within the posterior longitudinal ligament (PLL) of the lumbar spine and outer posterior annulus fibrosus of the intervertebral disc. In alternate embodiments, energy directed to nerves in the PLL may be from light or mechanical vibrations, or the nerves may be cooled. The electrodes may also be used diagnostically to correlate spontaneous nerve activity with spinal movement, fluctuations in autonomic tone and the patient's experience of pain. The electrodes may also be used to generate diagnostic evoked potentials. The diagnostic data are used to devise parameters for the therapeutic nerve stimulation. Automatic analysis of the data may be incorporated into a closed-loop system that performs the nerve stimulation automatically.
    Type: Application
    Filed: August 21, 2014
    Publication date: January 1, 2015
    Inventor: John D. LIPANI
  • Patent number: 8920459
    Abstract: An embolic coil detachment system includes an elongated, flexible polymer tube having a tubular wall with an inner surface defining an interior lumen. A distal portion of the tubular wall has a score line, and a resistive heating element is located near the score line and in immediate contact with a surface of a distal portion of the tubular wall, to provide direct heating of the distal portion of the flexible polymer tube adjacent to the score line. A therapeutic embolic coil includes a headpiece that is releasably attached within the distal portion of the flexible polymer tube, and that is releasable by heating of the distal portion of the tubular shaft to cause the distal portion of the tubular wall to split along the score line.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: December 30, 2014
    Assignee: DePuy Synthes Products, LLC
    Inventor: Juan A. Lorenzo
  • Patent number: 8911485
    Abstract: Devices and methods for warming or cooling blood flowing through the vasculature of a human or animal subject so as to alter or control the temperature of all or part of the subject's body. Heat exchangers are positioned within the subject's vasculature and heated or cooled heat exchange fluid is circulated through the heat exchanger. For certain therapeutic applications, the heat exchanger and associated elements of the system have sufficient power to lower the subject's body temperature by at least 3 degrees C. in less than 30 minutes.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: December 16, 2014
    Assignee: Zoll Circulation, Inc.
    Inventors: Ben F. Brian, III, Scott D. Wilson
  • Patent number: 8911486
    Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue). In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: December 16, 2014
    Assignee: Neuraxis, LLC
    Inventors: Michael Drnek, Dan Farley, John Sullivan
  • Publication number: 20140364926
    Abstract: A medical device is disclosed. The medical device may include an elongate member having a lumen extending at least partially between a proximal end and a distal end of the elongate member. The medical device may also include a plurality of legs coupled to a distal portion of the elongate member, and a distal end piece connected to each of the plurality of legs and located distally to the distal end of the elongate member. The medical device may also include an actuating member coupled to the distal end piece and extending between the plurality of legs and through the lumen. The reciprocal movement of the actuating member may be configured to reversibly move the plurality of legs from a first position to a second position. The medical device may also include a stopping member coupled to the actuating member and configured to limit a movement of the actuating member.
    Type: Application
    Filed: June 4, 2014
    Publication date: December 11, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Man Minh NGUYEN, Eric Karl LITSCHER
  • Publication number: 20140358183
    Abstract: Methods, systems, and devices are disclosed for cooling tissue, and in particular for applying therapeutic hypothermia to the spinal canal, tissue disposed within the spinal canal, and nerve roots extending from the spinal canal. Bone screws, intervertebral implants, stabilization rods, spinous process spacers, and other devices are described which define a chamber through which a chilled fluid, expandable gas, or other coolant means can be circulated, delivered, or activated to cool adjacent tissue. The degree of cooling can be regulated using a controller, which can be configured to increase or decrease the cooling effect based on any of a variety of measured or predicted physiological or thermodynamic properties. Methods are disclosed for implanting cooling instruments and for carrying out various treatment regimens that involve cooling tissue using such instruments.
    Type: Application
    Filed: August 2, 2014
    Publication date: December 4, 2014
    Inventors: Todd Sheppard Saunders, Jared Samuel Fry
  • Publication number: 20140350327
    Abstract: Provided herein are a device and method for attenuating posttraumatic stress syndrome, menopause symptoms, dysautonomia and pain by interfering with sympathetic chain signaling, particularly by blocking stellate ganglion conduction.
    Type: Application
    Filed: May 22, 2014
    Publication date: November 27, 2014
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Ada Shuk Yan Poon, Vijaykumar Rajasekhar, Kathryn Hammond Rosenbluth, Xiang Mackey Qian, Scott Delp, John Paderi, Tahel Altman
  • Publication number: 20140343350
    Abstract: Medical implants can comprise various instrumentation to impart desirable functionality to the implant. In some embodiments, the implants comprise functional structures, such as sensors, energy propagating transducers, drug delivery systems and the like. Additional instrumentation to facilitate the functionality of these devices can include, for example, microprocessors, communication systems, power sources or the like. Drug delivery systems can comprise, for example, an isolated reservoir with a control system to control the delivery of a biological agent from the reservoir. The implants can be orthopedic implants that are designed to interface with a patient's skeletal system wherein the orthopedic implant may itself embody sensors, processors, power supplies, memory and/or communication capability.
    Type: Application
    Filed: May 28, 2014
    Publication date: November 20, 2014
    Applicant: IZEX Technologies, Inc.
    Inventors: James B. Martinson, John G. Stark, Timothy J.B. Hanson, Steven Backes
  • Publication number: 20140316310
    Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
    Type: Application
    Filed: April 18, 2014
    Publication date: October 23, 2014
    Applicant: Oculeve, Inc.
    Inventors: Douglas Michael ACKERMANN, James Donald LOUDIN
  • Publication number: 20140316373
    Abstract: A device for topical cooling of the nervous system via cooling of cerebrospinal fluid, or CSF, using a solid thermally conductive material. The solid thermally conductive material is coupled to a heat exchange apparatus. The thermally conductive material may be coupled to any catheter that is used in existing clinical standard of care for acute neuronal injuries, such as catheters used to monitor and relieve intracranial pressure. The thermally conductive material is a biocompatible and solid material, for instance, metals such as steel, tungsten and titanium, and non-metallic materials such as thermal diamond paste.
    Type: Application
    Filed: April 21, 2014
    Publication date: October 23, 2014
    Inventor: Sanjay Dhall
  • Publication number: 20140309718
    Abstract: An in-ear stimulator for administering thermal stimulation to the ear canal of a subject includes (a) an earpiece configured to be insertable into the ear canal of said subject, the earpiece having an outer surface and an internal cavity formed therein, the internal cavity having an inner surface; and (b) at least one thermoelectric device thermally coupled to the earpiece internal cavity inner surface.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 16, 2014
    Applicant: Scion NeuroStim, LLC
    Inventors: Lanty L. Smith, Lesco L. Rogers
  • Publication number: 20140303701
    Abstract: The Low Temperature Hyperthermia System illuminates nano-particles, which are implanted in a living organism at the locus of the cancer or into the cancer cells, with a precisely determined energy field. This energy field ensures that the optimal cancer cell and cancer stem cell destruction temperature of 42° C. is not exceeded in the tissue, which minimizes the release of Heat Shock Proteins and cancer stem cells. The Low Temperature Hyperthermia System uses specially designed nano-particles that exhibit a specific temperature rise in a given illumination energy field and then have no further temperature rise even if the applied illumination energy field increases beyond the optimal level. Alternatively, the nano-particles exhibit a tightly controlled temperature rise based on a pre-determined illumination energy field strength. This innovative approach can also use radiation and/or chemotherapy in conjunction with the nano-particle illumination to kill the majority of the cancer cells.
    Type: Application
    Filed: June 19, 2014
    Publication date: October 9, 2014
    Inventors: Daniel B. McKenna, Robert J. Tondu
  • Patent number: 8845576
    Abstract: An electrosurgical tool for cauterizing or ablating patient tissue, which tool includes a tubular shaft which defines therein a conduit in communication with a suction source and which mounts an electrode at the distal end thereof. An electrode support element is provided at the distal end of the shaft for mounting and insulating the electrode. The support element and the electrode together define a suction opening at the treating surface of the electrode which minimizes clogging of the tool.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: September 30, 2014
    Assignee: Stryker Corporation
    Inventors: Steven C. Kramer, Andrew J. Hamel, Reid Cover
  • Publication number: 20140276783
    Abstract: Apparatus and methods for determining positioning of a energy delivery element include deploying a energy delivery element at a treatment site proximal to a vessel wall; using a multi-region pressure sensing apparatus to sense pressures applied in a plurality of directions about the energy delivery element; and determining an orientation of the energy delivery element based on the pressures measured in the plurality of directions about the energy delivery element.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 18, 2014
    Inventor: Nishant R. Srivastava
  • Publication number: 20140276539
    Abstract: A method in which a location is determined on the skin that is proximate to a sensory nerve that is associated with a painful condition. At least one needle of a cryogenic device is inserted into the location on the skin such that the needle is proximate to the sensory nerve. The device is activated such that the at least one needle creates a cooling zone about the sensory nerve, thereby eliminating or reducing severity of the painful condition.
    Type: Application
    Filed: September 12, 2013
    Publication date: September 18, 2014
    Applicant: MyoScience, Inc.
    Inventors: John Allison, Richard Radnovich, Jason Reynolds
  • Publication number: 20140276715
    Abstract: Systems and methods for mechanically heated catheter tips are provided. The systems include, for example: a catheter body with an axial lumen; a catheter tip with at least some of the tip constructed out of a high-friction, thermally-conductive material; a friction producing plug disposed in the axial lumen of the catheter tip and constructed at least in part out of a high-friction material; a drive wire running through the axial lumen of the catheter body being connected on the proximal end to a power source and on the distal end to the friction producing plug. Methods include using the drive wire to rotationally or axially translationally move the friction producing plug within the catheter tip. The friction produced by the movement of the friction producing plug and the inner wall of the catheter tip generates heat which can be conducted outward by the thermally conductive material.
    Type: Application
    Filed: March 6, 2014
    Publication date: September 18, 2014
    Applicant: Gyrus ACM, Inc. (d.b.a Olympus Surgical Technologies America)
    Inventors: Brandon J. Shuman, Clint Finger
  • Publication number: 20140277305
    Abstract: Methods, devices, and systems for temperature management and ventricular defibrillation are disclosed. Methods, devices, and systems for positioning an electrode in the esophagus of a subject and managing the core body temperature of the subject are disclosed. The use of esophageal heat transfer devices to deliver an electrode for use in delivering an electrical shock to the myocardium is disclosed.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Advanced Cooling Therapy, LLC
    Inventors: Erik Kulstad, Patrick Shanley
  • Publication number: 20140257147
    Abstract: A system includes an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
    Type: Application
    Filed: May 20, 2014
    Publication date: September 11, 2014
    Applicant: NeuroPace, Inc.
    Inventors: Michael Sasha JOHN, Benjamin D. PLESS, Brett WINGEIER
  • Patent number: 8828068
    Abstract: Disclosed herein, among other things, is a device for providing a localized vasomodulation of a vessel. According to an embodiment, the device includes a thermal element configured to conduct thermal energy between the thermal element and a desired region of the vessel wall to elicit the localized vasomodulation of the vessel at the desired region. The device also includes a controller operationally connected to the thermal element. The controller is adapted to control the conduction of thermal energy between the thermal element and the desired region of the vessel wall to control the localized vasomodulation of the vessel at the desired region. In various embodiments, a sensor connected to the device provides feedback to the controller.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: September 9, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Shantha Arcot-Krishnamurthy, Allan C. Shuros, Jihong Qu
  • Publication number: 20140249524
    Abstract: Systems and methods for monitoring and performing tissue modulation are disclosed. An example system may include an elongate shaft having a distal end region and a proximal end and having at least one ablation electrode disposed adjacent to the distal end region. The system may further include a control unit for controlling the power level and duration of the modulation procedure.
    Type: Application
    Filed: February 28, 2014
    Publication date: September 4, 2014
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: GORDON J. KOCUR
  • Publication number: 20140243941
    Abstract: An in-ear stimulation device for administering caloric stimulation to the ear canal of a subject includes (a) first and second earpieces configured to be insertable into the ear canals of the subject; (b) at least first and second thermoelectric devices thermally coupled to respective ones of the first and second earpieces; (c) a first heat sink thermally coupled to the first thermoelectric device opposite the first earpiece and a second heat sink thermally coupled to the second thermoelectric device opposite the second earpiece; and (d) a controller comprising a waveform generator in communication with the first and second thermoelectric devices, the waveform generator configured to generate a first control signal to control a first caloric output to the first thermoelectric device and a second control signal to control a second caloric output to the second caloric device.
    Type: Application
    Filed: December 16, 2011
    Publication date: August 28, 2014
    Inventors: Lesco L. Rogers, Lanty L. Smith, Robert D. Black
  • Patent number: 8808345
    Abstract: The present disclosure comprises handle assemblies for intravascular treatment devices. In one embodiment, a handle assembly comprises an actuator for deflecting a distal region of an intravascular treatment device. In one embodiment, a handle assembly comprises a rotator for rotating an intravascular treatment device independently of the handle assembly. In one embodiment, a handle assembly comprises a rotation limiting element for limiting independent rotation of an intravascular treatment device relative to the handle assembly. Methods and systems for intravascular delivery, deflection and placement of an intravascular treatment device via a handle assembly of the present invention are also provided.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: August 19, 2014
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Benjamin J. Clark, William R. George, Kenneth J. Michlitsch, John Paul Sam, Erik Thai, Andrew Wu
  • Publication number: 20140222122
    Abstract: Intra-vaginal devices and methods are disclosed for a broad range of applications in the women's health field. The devices and methods provide for placement in the cervical region, and for transferring heat to a cervical region, a barrier contraception method, collection of menstrual fluid, and release of drugs and/or hormones intra-vaginally. The device also can address multiple women's health issues.
    Type: Application
    Filed: April 9, 2014
    Publication date: August 7, 2014
    Inventors: Stacy L. Feemster, Terry W. Alsberg
  • Publication number: 20140214139
    Abstract: Methods and devices are disclosed herein that generally involve cooling tissue (e.g., localized cooling of tissue), and in particular applying therapeutic hypothermia to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled by clamping a cooling instrument to a bone or implant that is proximate to the tissue. The cooling instrument can define a chamber through which a chilled fluid, expandable gas, or other coolant means can be circulated, delivered, or activated to cool adjacent tissue. The degree of cooling can be regulated using a controller, which can be configured to increase or decrease the cooling effect based on any of a variety of measured or predicted physiological or thermodynamic properties. Methods are disclosed for utilizing cooling instruments and for carrying out various treatment regimens that involve cooling tissue using such instruments.
    Type: Application
    Filed: March 24, 2014
    Publication date: July 31, 2014
    Applicant: Neuraxis, LLC
    Inventor: John Sullivan
  • Publication number: 20140214140
    Abstract: The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter is inserted through an incision into a large blood vessel of a patient. By selectively heating or cooling a portion of the catheter lying within the blood vessel, heat may be transferred to or from blood flowing within the vessel and the patient's body temperature may thereby be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia and hyperthermia, or for inducing a condition of artificial hypothermia when desired. The method and system further provide for the cooling of initially hypothermic patients whose blood or body temperature has been warmed above the desired target level and the warming of initially hyperthermic patients whose blood or body temperature has been cooled below the desired target temperature.
    Type: Application
    Filed: January 2, 2014
    Publication date: July 31, 2014
    Applicant: ZOLL Circulation, Inc.
    Inventor: Robert Ginsburg
  • Publication number: 20140200479
    Abstract: Some embodiments described herein generally relate to apparatus and methods for treating diverticula. The diverticula may be present within a wall of a gastrointestinal organ, such as a colon, of a human or animal. In some examples, the apparatus may include a flexible conduit having a proximal end, a distal end, and a passageway therethrough, a balloon-forming chamber at the distal end of the flexible conduit, and at least one heating element positioned on an interior of the balloon-forming chamber. The apparatus may further include an endoscope in which the flexible conduit may be positioned such that the balloon-forming chamber extends from an end of the endoscope.
    Type: Application
    Filed: January 15, 2013
    Publication date: July 17, 2014
    Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC
    Inventor: Masaaki Mihara
  • Publication number: 20140188103
    Abstract: A thermal neuromodulation apparatus, system, and methods for the ablative and non-ablative application of thermal energy to the nerves of a patient are disclosed. The thermal neuromodulation apparatus includes an elongated, hollow body configured to traverse the tortuous intravascular pathways of the renal vasculature and includes an expandable structure bearing electrodes and configured to selectively apply thermal energy via electric fields to the renal nerves through a vessel wall. The thermal neuromodulation apparatus may also include optical-acoustic sensors and an imaging apparatus to obtain data from the treatment area before, during, and after neuromodulation to monitor and/or control the neuromodulation process.
    Type: Application
    Filed: December 23, 2013
    Publication date: July 3, 2014
    Applicant: Volcano Corporation
    Inventor: Bret C. Millett
  • Patent number: 8753382
    Abstract: The present invention relates to a portable apparatus for warming biocompatible fluids for use in the treatment of injured patients and a method of heating a biocompatible fluid to treat a patient experiencing hypothermia. The present invention may be used to warm intravenous fluids for trauma resuscitation or to warm air from a ventilator circuit. The portable nature of the present invention makes it highly suitable for field applications, such as a forward surgical hospital near a combat zone.
    Type: Grant
    Filed: January 17, 2011
    Date of Patent: June 17, 2014
    Assignee: The Board of Regents of the University of Texas Systems
    Inventors: Brijesh Gill, Charles Cox, Ofodike A. Ezekoye, Ozgur Ekici
  • Publication number: 20140148735
    Abstract: Methods, systems, and devices are described for treating ischemia in heart tissue after a heart attack. A method includes providing a heat treatment device comprising a heating element, positioning the heating element in proximity to the heart tissue, and heating the heart tissue with the heating element to generate release of heat shock proteins in the heart tissue. The heat shock proteins may also be provided via delivery of a drug. The heat shock proteins can provide myocardial protection for the heart tissue.
    Type: Application
    Filed: October 15, 2013
    Publication date: May 29, 2014
    Applicant: COVIDIEN LP
    Inventor: WILLIAM H. NAU, JR.
  • Patent number: 8734499
    Abstract: Disclosed herein, among other things, is system for thermal neuroinhibition. According to an embodiment, the system includes at least one implantable fluid-filled conduit adapted to be placed adjacent to a neural target. The system also includes an implantable housing including a power source, a heat pump deriving power from the source and connected to the conduit, and a controller within the housing. The controller is connected to the heat pump, and is adapted to control the heat pump to effect fluid flow in the conduit to cool the neural target using electromechanical refrigeration to reversibly inhibit neural activity as part of a medical treatment.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: May 27, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Eric G. Lovett, Imad Libbus, Joseph Walker