Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

Abstract: The invention relates to a device for the electrostimulation therapy of the human body, comprising several electrodes (1) that contact the body surface and apparatuses (3-5) for applying voltage to the electrodes (1). According to the invention, the electrodes are arranged in a line and the apparatuses are provided to apply voltage to the electrodes (1) consecutively along the line.

Abstract: Temporarily or permanently implantable medical device, having at least one longitudinally extended first electrical conductor having a functional lead, which is connected to a functional electrode pole for dispensing therapeutic signals or for detecting diagnostic signals, and including at least one second electrical conductor, which is coupled to the functional lead and is guided with it in a shared insulating sheathing, such that a coupling between the functional lead and the second electrical conductor is designed to input electromagnetic radiofrequency waves guided in the functional lead at least partially into the second electrical conductor.

Abstract: Implementations disclosed herein provide for a microneedle electrode system comprising a microneedle electrode patch connected to external electronics. The microneedle electrode patch comprises a first flexible substrate having a plurality of conductive pads disposed thereon, a plurality of three-dimensional, individually addressable microneedle electrode arrays where each array has a plurality of microneedles extending from an upper surface thereof and a lower surface adapted to contact a corresponding one of the plurality of conductive pads disposed on the first substrate, and a second flexible substrate having a plurality of openings defined therein dimensioned to accommodate at least a portion of the upper surface of the microneedle electrode array from which the microneedles extend.

Abstract: A method of treating a wide variety of heretofore considered unrelated ailments comprises delivering electricity through a circuit in the body. The circuit includes at least four nerves leading from at least two of the patient's extremities to various nerve roots adjacent the spinal column. Electrical energy from an electrical interferential therapy device is delivered through electrodes on the extremities adjacent the nerve endings until symptoms of the diagnosed ailment ameliorates. Sending impulses from the periphery to the central nervous system appears to the help the body manufacture various neuropeptides and other chemicals which control the essential basics of the body's health and well being.

Abstract: A focal tissue stimulator is provided that includes a pair of concentric conductors. The conductors may include an inner conductor, and an outer conductor that has an elliptical annular shape and surrounds the inner conductor. The outer conductor may have a minor axis and a mutually-perpendicular, major axis, with a first portion of the outer conductor proximate the minor axis being closer in proximity to the inner conductor than a second portion of the outer conductor proximate the major axis. In this regard, the inner and outer conductors may be coupled or couplable to respective leads configured to deliver current for passage therebetween, with the elliptical annular shape of the outer conductor creating a pathway of increased current density at the first portion relative to the second portion.

Abstract: A stimulation therapy device provides an electrical stimulation therapy to branches of the tibial nerve of a patient. The device comprises a support member configured to be worn around the ankle or foot of the patient, first and second pairs of electrodes attached to the support member, and a stimulation circuit attached to the support member. The stimulation circuit is configured to deliver electrical stimulation pulses through the first and second pairs of electrodes.

Abstract: A conductive garment. Conductive fabric sections are each separated by a nonconductive strip. An electrical contact is connected to each conductive fabric section. An attachment pad connects the conductive garment to a support wrap. The nonconductive strip is a sufficient width so that it is able to cover a section of the human body where the user does not want electricity applied. In a preferred embodiment, the nonconductive strip is of sufficient width to cover the spine of a human being.

Abstract: The present disclosure relates to methods, devices and systems used for the treatment of mood, anxiety, post traumatic stress disorder, and cognitive and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.

Abstract: An electro-acupuncture device for controlling over active bladder is described. The device includes a housing, circuitry for generating electro-acupuncture stimulus disposed within the housing, and at least one strap for securing the housing to the ankle. The device also includes a pair of D-shaped electrodes received within the bottom outer surface of the housing. The housing of the device is flexible with a low profile and is shaped so that it is conformal to a person's ankle. When the device is strapped to a patient's ankle, the electrodes contact the ankle and provide electric stimulation to the tibial nerve within the ankle.

Abstract: Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

Abstract: Provided is a device for strengthening a pelvic floor muscle. The device for strengthening a pelvic floor muscle includes a device body provided with a seating means on which a user can sit; and two or more electrode pads for applying a low frequency pulse, the electrode pads being disposed around a portion of the device body corresponding to the user's anus. In addition, a method for controlling the device for strengthening a pelvic floor muscle includes separately applying the generated low frequency pulse in a ramp up (Ru) time, a hold (Ht) time and a ramp down (Rd) time.

Abstract: An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.

Abstract: The present invention relates to systems and techniques for stimulating a user. For example, materials and methods for manipulating nystagmus and the related vestibular system with coupling of galvanic vestibular stimulation (GVS) and visual cueing are provided herein. Use of GVS within the present invention may be applied to simulation, alleviating motion sickness, and directional cueing of a user to a precise target location.

Abstract: An electrode for applying electric fields to a patient includes a plurality of ceramic elements (e.g., ceramic discs) that are designed to be positioned against the patient's skin. Electrical connections are made to the ceramic elements (e.g., using a flex circuit). Temperature sensors (e.g., thermistors) are preferably provided at at least some of the ceramic elements to sense the temperature at the skin beneath the ceramic elements, so that appropriate action can be taken if an overtemperature condition is detected.

Abstract: An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

Abstract: A medical instrument for delivering electrotherapy to tissue that includes an outer support member having a ground plate at a distal end of the outer support member, and a protrusive element having a tip that extends beyond the ground plate. A portion of the protrusive element proximate the ground plate can act as an electrical insulator and a portion of the protrusive element proximate the distal end of the protrusive element can include a first electrode. The protrusive element can be designed to penetrate into tissue below a tissue surface while a tissue contacting surface of the ground plate rests against the tissue surface. Also disclosed are systems incorporating the medical instrument and methods of electrotherapy to subsurface tissue using the medical instrument.

Abstract: A microelectrode array having a substrate with a plurality of grooves and a plurality of electrical contact pads, the grooves each with at least one electrode electrically connected to at least one of the electrical contact pads, each of the grooves containing at least one myotube that overlays the at least one electrode.

Abstract: A method and system of providing therapy to a patient implanted with an array of electrodes is provided. Electrical stimulation current is conveyed from at least two of the electrodes to at least one of the electrodes along at least two electrical paths through tissue of the patient, and the electrical stimulation current is shifted between the electrical paths by actively adjusting one or more finite resistances respectively associated with one or more of the electrical paths.

Abstract: A method for treating a patient by covering a tissue region with a electric field capable of transiently or permanently permeabilizing cells in said tissue region, comprising the steps of: a. positioning the electrodes of an electrode device in a tissue region to be treated; and b. creating a specific polarity pattern by applying to a first subset of electrodes comprising at least two electrodes a first polarity while at the same time applying to a second subset of electrodes comprising at least two electrodes a second polarity.

Abstract: A device for altering cardiac performance includes an energy absorbing element which absorbs cardiac pumping energy from at least a portion of the heart. The energy may be delivered to another part of the body, such as another portion of the heart, to perform useful work such as providing blood pumping assistance.

Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high Impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies. The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli. The devices can include at least one electrode.

Abstract: An implantable stimulation system including an epidural lead for spinal cord stimulation that includes a paddle having an array of electrodes coupled to conductors within the lead body. The paddle includes score lines that extend along the length and width of either the front or back facets of the paddle portion. The score lines increase the flexibility of the paddle in both the length and width directions which facilitate the implantation of the paddle within the epidural space of the spinal cord, and further permits the paddle to conform more uniformly to the target area of implantation to minimize the gap between the electrodes and targeted fibers.

Abstract: An implantable stimulation system including an epidural lead for spinal cord stimulation that includes a paddle having an array of electrodes coupled to conductors within the paddle body. The paddle is elongated in shaped with the distal end of the paddle having a tabbed or extended portion with the lead exiting the extended portion of the paddle an angle relative to the longitudinal axis of the paddle.

Abstract: An apparatus for personal aesthetic skin treatment by RF voltage. The apparatus includes an RF voltage supply and a disposable patch with an assembly of individual electrodes operative to contact segments of the skin and deliver to each contact RF voltage. The RF voltage may be supplied to each of the electrodes according to a predetermined experimentally established skin treatment protocol. The treatment RF current generated by the applied RF voltage heats the skin and is applied intermittently to different electrodes being in contact with the skin in an order and duration sufficient to cause the desired skin effect and enable proper cooling of earlier treated skin segments. The selected protocol ensures safe non-ablative skin treatment parameters.

Abstract: A radiofrequency ablation device includes an elongate cannula having a distal portion and a proximal portion and a lumen extending between the distal and proximal portions. The RF ablation device further includes an elongate tubular member disposed within the lumen of the elongate cannula, the elongate tubular member having a distal region and a proximal region, the elongate tubular member including a lumen extending between the distal and proximal portions. A sildable electrode member is disposed in the portion of the elongate cannula lumen located external to the elongate tubular member. As an alternative to the elongate tubular member, the electrode member may include a lumen. The lumen of the elongate tubular member (or electrode member) carries or vents gaseous vapor generated during the RF ablation process.

Abstract: A lead assembly for an electrical stimulation system includes terminals disposed along a proximal end of a lead body and electrodes disposed along a distal end of the lead body. The electrodes include segmented electrodes. At least one distal marker is disposed along the distal end of the lead body. The distal marker identifies the circumferential position of at least one of the segmented electrodes along the lead body. The distal marker is aligned with at least one of the segmented electrodes along the longitudinal length of the lead body. At least one proximal marker is disposed along the proximal end of the lead body. The proximal marker is aligned with the distal marker along the longitudinal length of the lead body. The distal marker and the proximal marker are discontinuous with one another along the lead body.

Abstract: An AED includes defibrillation circuitry housed within an enclosure, a first processor programmed to periodically test the operability of the defibrillation circuitry and a second processor in communication with the first processor. The AED further includes a visual indicator, such as a red/green LED, positioned at the exterior of the enclosure that is operatively connected to the second processor. The second processor is programmed to control the visual indicator in response to the periodic test results provided to it by the first processor.

Abstract: An integrated system and method for treatment of various diseases, including psychiatric, mental and brain disorders, which preferably combines personalized non-invasive neuronal brain stimulation together with appropriate personalized cognitive training, and which iteratively fine-tunes this treatment by monitoring specific cognitive and brain functions in response to the treatment. A novel brain stimulator device and method, Computerized Magnetic Photo-Electric Stimulator (CCMPES), is described, which integrates electromagnetic stimulation with laser stimulation to generate a magnetic photo-electric stimulation.

Abstract: A disposable electrode paddle assembly is provided and includes a shaft having a proximal end and a distal end; a handle assembly supported at the proximal end of the shaft; a spoon supported at the distal end of the shaft; an electrical conductor extending from the handle assembly and establishing an electrical connection at the spoon; and an electrode assembly selectively, electrically connectable to the electrical connection provided at the spoon; wherein the electrode assembly includes a layer of silver/silver-chloride (Ag/AgCl) having one of an increasing and decreasing density extending in a radially outward direction.

Abstract: An AED includes defibrillation circuitry housed within an enclosure, a first processor programmed to periodically test the operability of the defibrillation circuitry and a second processor in communication with the first processor. The AED further includes a visual indicator, such as a red/green LED, positioned at the exterior of the enclosure that is operatively connected to the second processor. The second processor is programmed to control the visual indicator in response to the periodic test results provided to it by the first processor.

Abstract: An apparatus includes a flexible lead body extending from a proximal end to a distal end, an expandable electrode coupled proximate the distal end, the expandable electrode having an expanded diameter dimensioned to abut a wall of a pulmonary artery, and an implantable pulse generator electrically coupled to the expandable electrode. The expandable electrode includes a plurality of electrode zones. The plurality of zones can be tested to determine which zone delivers the best baroreflex response. At least one of the electrode zones can be selected to deliver a stimulation signal based on the testing. The implantable pulse generator is adapted to deliver a baroreflex stimulation signal to a baroreceptor in the pulmonary artery via the electrode.

Abstract: An electrical lead for implantation into an animal includes a cable to which a stimulation electrode is connected. The cable has a helical electrical conductor enclosed within an insulating sheath. The stimulation electrode has a tubular first contact band with a threaded lumen into which a portion of the helical electrical conductor is screwed. A second contact band has a threaded aperture and a helical electrode coil is screwed into both the threaded lumen and the threaded aperture. The two contact bands are separated so as to expose a portion of the electrode coil to enable electrical stimulation of tissue of the animal. Particular configurations of the helical electrode coil and the helical electrical conductor render the electrical lead compatible with MRI scanning.

Abstract: An external controller/charger system for an implantable medical device is disclosed, in which the external controller/charger system provides automatic switching between telemetry and charging without any manual intervention by the patient. The external controller/charger system includes an external controller which houses a telemetry coil and an external charging coil coupled to the external controller. Normally, a charging session is carried out using the external charging coil, and a telemetry session is carried out using the telemetry coil. However, when a patient requests to carry out telemetry during a charging session, the external charging coil is used instead of the internal telemetry coil.

Abstract: This disclosure relates to a medical electrical lead having fault detection and fault isolation. The lead may include a first conductor coupled to a first electrode and a second conductor coupled to a second electrode. A capacitor is disposed within the lead and selectively coupled to the first and second conductors of the lead. The capacitor is charged in a test mode of operation after the first and second electrodes have been isolated from the conductors via an isolation mechanism and the capacitor will discharge through the first and second conductors. The capacitor discharge morphology is processed to detect lead-related conditions.

Abstract: An apparatus comprises a flexible substrate including a modular electrode array disposed on the flexible substrate. The modular electrode array includes a plurality of electrode modules, where an electrode module includes a plurality of electrodes. The flexible substrate also includes a spatial separation between the electrode modules of the modular electrode array, and conductive interconnect coupled to the electrodes of the plurality of electrodes.

Abstract: A lead assembly includes a lead with a distal end and a proximal end. The lead includes a plurality of electrodes disposed at the distal end and a plurality of terminals disposed at the proximal end. The lead also defines at least one central lumen and a plurality of outer lumens. The central and outer lumens extend from the proximal end to the distal end such that the plurality of outer lumens extend laterally from the at least one central lumen. The lead further includes a plurality of conductive wires. Each conductive wire couples at least one of the plurality of electrodes electrically to at least one of the plurality of terminals. At least two conductive wires are disposed in each of the plurality of outer lumens.

Abstract: A lead connector is terminated proximally by a connector pin and includes a circumferential array of connector pads, each connector pad coupled to an electrode via an elongated insulated conductor. A lumen of an adaptor is adapted to engage the lead connector and includes an electrical contact zone formed therein and positioned for coupling with a one of the array of connector pads, when the connector is engaged within the lumen, in order to facilitate electrical connection of a selected electrode corresponding to the one of the array of connector pads.

Abstract: Disclosed herein is a functional electrical stimulation (FES) device and system. In one embodiment, sequential bipolar pulse stimulation may be provided to an area of a living body via one or more electrode leads applied to the area via a FES device comprising a current pulse generating circuit comprising output nodes for operative coupling to the one or more electrode leads, and configured for operative coupling to a voltage supply. The current pulse generating circuit generally comprises positive and negative stimulation paths drawing from the voltage supply to respectively apply positive and negative currents through the area via the one or more electrode leads. In one example, the stimulation paths comprise respective capacitive elements, a capacitance ratio of which dictating, at least in part, an amplitude ratio of the positive and negative currents, wherein periodic alternative activation of the stimulation paths provides the sequential bipolar pulse stimulation.

Abstract: The invention provides an implant, system and method for electrically stimulating a target tissue to either activate or block neural impulses. The implant provides a conductive pathway for a portion of electrical current flowing between surface electrodes positioned on the skin and transmits that current to the target tissue. The implant has a passive electrical conductor of sufficient length to extend from subcutaneous tissue located below a surface cathodic electrode to the target tissue. The conductor has a pick-up end which forms an electrical termination having a sufficient surface area to allow a sufficient portion of the electrical current to flow through the conductor, in preference to flowing through body tissue between the surface electrodes, such that the target tissue is stimulated to either activate or block neural impulses. The conductor also has a stimulating end which forms an electrical termination for delivering the current to the target body tissue.

Abstract: The present embodiments are directed to implantable electrode arrays having virtual electrodes. The virtual electrodes may improve the resolution of the implantable electrode array without the burden of corresponding complexity of electronic circuitry and wiring. In a particular embodiment, a virtual electrode may include one or more passive elements to help steer current to a specific location between the active electrodes. For example, a passive element may be a metalized layer on a substrate that is adjacent to, but not directly connected to an active electrode. In certain embodiments, an active electrode may be directly coupled to a power source via a conductive connection. Beneficially, the passive elements may help to increase the overall resolution of the implantable array by providing additional stimulation points without requiring additional wiring or driver circuitry for the passive elements.

Abstract: Disclosed are a method and a device useful for performing cosmetic or medical procedures of an in vivo portion of tissue. The method includes contacting an in vivo portion of tissue with a portion of a pad, substantially saturating the pad with a reactant, contacting the pad with a first electrode so that the first electrode is proximate to the portion of the pad proximate to the in vivo portion of tissue. The method further includes contacting the pad with a second electrode so as to provide an electrical path between the first electrode and the second electrode through the reactant, passing a DC voltage through a circuit including the first electrode, the reactant and the second electrode, thereby forming at least one of: an electrolytic effect, and an electrolytic product of the reactant, proximate to the first electrode.

Abstract: An electrode array with a flexible array substrate on which plural spaced apart electrodes are disposed. Integrated circuits are disposed in the array substrate. The integrated circuits are mounted to package substrates. The package substrates are more rigid than the array substrate. Internal to each package substrate is at least one electrical conductor. The electrical conductor extends from a bond pad integral with integrated circuit at least partially through the package substrate. The electrical conductor functions as the conductive member that extends between the integrated circuit an electrode with which the integrated circuit is associated.

Abstract: A medical electrode includes a conductive member having a top and a bottom side and a plurality of cutouts establishing a pattern of islands interconnected by conductive member bridges. A plurality of island electrodes are provided with each island electrode disposed on a corresponding island. A conductive adhesive is disposed on the conductive member bottom side for adhering the medical electrode to a patient's skin.

Abstract: The invention relates to a device for the electrostimulation therapy of the human body, comprising several electrodes (1) that contact the body surface and apparatuses (3-5) for applying voltage to the electrodes (1). According to the invention, the electrodes are arranged in a line and the apparatuses are provided to apply voltage to the electrodes (1) consecutively along the line.

Abstract: A medical device compatible with magnetic resonance imaging including an elongated tubular body defining a longitudinal axis and having opposed proximal and distal end portions. The elongated body including a plurality of coaxial layers including a radially inner-most insulative layer, at least one inner conductive layer, and a radially outer-most insulative layer. The at least one conductive layer is defined by a non-ferromagnetic conductive material that is compatible with magnetic resonance imaging.

Abstract: A visual prosthesis which includes a hermetic package and flexible circuit electrode array is disclosed. The hermetic package includes electrode drivers and contacts. The flexible circuit electrode array includes a polymer base layer, metal traces, including electrodes suitable to stimulate visual neural tissue and bond pads bonded to contacts on the hermetic package, all deposited on the polymer base layer, a polymer top layer deposited on the polymer base layer and deposited on the metal traces, a partial or an entire coating of the polymer base layer and of the polymer top layer by a soft polymer that is softer than the polymer base layer; and the polymer base layer and the polymer top layer contain a plurality of aligned holes to facilitate bonding of the soft polymer.

Abstract: An earlier intrinsic activation and a later intrinsic activation of a right ventricle and a left ventricle are determined. This information is used for computing a biventricular pacing interval as a function of an interval from a pacing energy delivered to a ventricle corresponding to the later intrinsic activation and a depolarization sensed in a ventricle having earlier intrinsic activation, the depolarization evoked in response to the pacing energy.

Abstract: A lead for use in Deep Brain Stimulation (DBS) and similar applications has a rigid lead tip with multiple electrodes thereon. The electrodes are formed by coating a lead tip core with a conductive material; selectively removing the conductive material to define the electrodes and conductive tracks leading therefrom; and then applying a layer of insulating material over the tracks to leave the electrodes exposed. Terminals are also left exposed on the tracks for connection to energy supply and/or data transmission lines. Such lines are preferably provided on or within a flexible lead body connected to the lead tip.

Abstract: Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.