Abstract: Systems and methods are disclosed herein for providing a configuration code for customizing a glucose level control system for at least an initial period. The configuration code can be based on one or more dosing parameters from a tracked medicament therapy administered to a subject over a tracking period by the glucose level control system. The configuration code includes encoded dosing parameters including a correction dosing parameter based on at least some of the correction boluses of medicament administered during the tracking period, a food intake dosing parameter comprising an indication of a food intake bolus size of medicament based on one or more food intake boluses provided during the tracking period, and a basal dosing parameter based on at least some of the basal doses of medicament administered during the tracking period.

Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device and preventing or retarding the formation of a biofilm.

Abstract: The invention relates to a surgical instrument capable of applying an electrostimulation to a neural structure. The surgical instrument also has a tracking system associated therewith to provide navigational tracking during a surgical procedure.

Abstract: A portable combination medical therapy device that integrates the collective beneficial characteristics of five separate and distinct therapeutic pain relieving, relaxing, stimulating and healing modalities. The device comprises an applicator head that contains: at least two electrically conducting electrodes, a vibration mechanism, light mechanism, heat mechanism and is functionally designed to enable the operator to apply varying pressure and movement to the tissue being treated. The beneficial healing, relaxing and pain relieving results are enhanced because of the convenience and synergistic effect that the portable multiple healing modalities provide.

Abstract: A tissue tensioning electrostimulator device. The device includes a plurality of laterally separable electrodes for placement against bodily tissue and for discharging electric current thereon. The device also includes a power circuit in electrical communication with the electrodes and electrically connectable to a power supply for energizing the electrodes. The device also includes stored electrotherapy regimens based on user characteristics. The device also includes a microprocessor having logic for selecting an electrotherapy regimen for a user of the tissue tensioning electrostimulator device based on characteristics of the user of the tissue tensioning electrostimulator device.

Abstract: A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.

Abstract: A tissue tensioning electrostimulator device. The device includes a plurality of laterally separable electrodes for placement against bodily tissue and for discharging electric current thereon. The device also includes a power circuit in electrical communication with the electrodes and electrically connectable to a power supply for energizing the electrodes.

Abstract: An electrosurgical instrument comprises a handpiece, a monopolar electrode unit having a single treatment electrode projecting from the handpiece, a radio-frequency generator and a battery within the handpiece for powering the generator. The generator has a single direct radio-frequency output patient connection through the treatment electrode. The return path between the generator and a patient is through an electrically conductive shield around the generator and forming part of the handpiece, the shield forming a capacitive coupling element between the generator and the surroundings. Preferably, the operating frequency of the generator is 5 MHz or greater.

Abstract: A low-frequency electrotherapeutic device can overcome problems ascribable to tolerance in neural response and problems ascribable to accumulation of electric charge in a living body, thereby affording a comfortable massaging effect. Each electrode can be designated as a different electrode or as an indifferent electrode by a controller. Electrodes do not assume a fixed paired structure, and the path of stimulating electric current is changed at predetermined intervals by scanning electrodes serving as different electrodes. The path of an electric current flowing on the skin of a living body can be changed in various ways, the number of which corresponds to the number of paths connecting the electrodes. Consequently, it becomes possible to freely select a desired electric current path or a desired combination of electrodes in accordance with a program stored in a control section (CPU) incorporated in the controller. Also, it becomes possible to automatically change the combination at predetermined intervals.

Abstract: A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background.

Abstract: An electrical human skin treatment apparatus which comprises a housing within which is incorporated an electrical circuit. The housing includes a pair of terminals which are spaced apart. The user's hand must be in contact with one terminal with the other terminal to be in contact with the area of application such as the face or neck of the user. The electrical circuit includes a slow voltage current rise to minimize the possibility of electrical shock to the user. A switch is incorporated on the exterior of the housing to not only activate the apparatus, but also to select anaphoresis or cataphoresis.

Abstract: A transdermal medication system wherein said medication is selectively dispensed on-demand from multiple reservoirs within a disposable patch so as to vary the drug choice and the drug concentration, and thereby the regimen and release rate. In a preferred embodiment electric resistance heating activates multiple heat-shrink polymer reservoirs into an absorbent layer for transdermal passage. An embodiment of the invention dispenses a heated moisturizing fluid to facilitate transdermal transfer. In another embodiment, depletion indication is provided.

Abstract: A dry-state iontophoretic drug delivery device (10, 20) is provided. The device has drug and electrolyte reservoirs (15, 16) which are initially in a non-hydrated condition. In one embodiment of the invention, a passageway (21, 22) is provided through the backing layer (13) and the electrode layer (11, 12) of both the donor electrode assembly (8) and the counter electrode assembly (9). Water or other liquid can be introduced through these passageways (21, 22) in order to hydrate the drug and electrolyte reservoirs (15, 16) and activate the device (10). In another embodiment of the device (20), the drug and electrolyte reservoirs (15, 16) are initially separated from their respective electrodes (11, 12). After the reservoirs (15, 16) are hydrated, they are placed in electrical contact with their respective electrodes (11, 12). By joining the reservoir (15, 16) to the electrode (11, 12) after hydration occurs, delamination problems are reduced.

Abstract: A two phase adhesive matrix for use in an electrically powered iontophoretic delivery device is provided. The adhesive matrix comprises an adhesive hydrophobic polymer phase and about 15 to 60 wt. % on a dry weight basis of a hydrophilic polymer phase distributed through the hydrophobic polymer phase. The hydrophilic phase forms upon hydration an interconnecting network of aqueous pathways for passage of the agent through the adhesive. The adhesive can be used to adhere an electrode assembly of an iontophoretic delivery device to a body surface such as skin or a mucosal membrane. Alternatively, the adhesive can be used to adhere together two or more elements of an iontophoretic delivery device.

Abstract: A hydratable iontophoretic bioelectrode including a plurality of layers of material capable of absorbing and holding an ionized fluid when placed in contact with the fluid. In one embodiment, a layer of a highly crosslinked dry hydrogel is used with a second layer of a more lightly crosslinked dry hydrogel. When the lightly crosslinked hydrogel layer is located so as to be in contact with the skin during iontophoresis, the medicament ions will be concentrated next to the skin. When the more highly crosslinked layer is located next to the conductive member, the undesirable effects of hydrolysis or corrosion of the conductive member are lessened. In another embodiment, adjacent layers are maintained at least partially out of contact from one another so as to improve the rate of hydration by disposition between the layers of spacing elements such as sugar or other dissolvable particles or cellulose or by forming a three dimensional pattern thereon.

Abstract: An electrical human skin treatment apparatus which comprises a housing within which is incorporated an electrical circuit. The housing includes a pair of terminals which are spaced apart. The user's hand must be in contact with one terminal with the other terminal to be in contact with the area of application such as the face or neck of the user. The electrical circuit includes a slow voltage current rise to minimize the possibility of electrical shock to the user. A switch is incorporated on the exterior of the housing to not only activate the apparatus, but also to select anaphoresis or cataphoresis.