Correcting Spinal Deformities Patents (Class 607/43)
  • Patent number: 11931572
    Abstract: A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.
    Type: Grant
    Filed: December 24, 2020
    Date of Patent: March 19, 2024
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Simeng Zhang, Hyun-Joo Park, Erika Ross
  • Patent number: 11872394
    Abstract: Described herein are systems and methods for the treatment of pain using electrical nerve conduction block (ENCB). Contrary to other methods of pain treatment, the ENCB can establish a direct block of neural activity, thereby eliminating the pain. Additionally, the ENCB can be administered without causing electrochemical damage. An example method can include: placing at least one electrode contact in electrical communication with a region of a subject's spinal cord; applying an electrical nerve conduction block (ENCB) to a nerve in the region through the at least one electrode contact; and blocking neural activity with the ENCB to reduce the pain or other unwanted sensation in the subject.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: January 16, 2024
    Assignees: CASE WESTERN RESERVE UNIVERAITY, NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
    Inventors: Niloy Bhadra, Narendra Bhadra, Kevin L Kilgore, Scott Lempka, Jesse Wainright, Tina Vrabec, Manfred Franke
  • Patent number: 11612753
    Abstract: A method for remote programming a therapy device for neurostimulation comprises: generating a stimulation program for the therapy device by means of a clinician programmer; transferring the stimulation program to a patient programmer; loading the stimulation program on the therapy device from the patient programmer; and increasing a stimulation amplitude of the stimulation program by means of the patient programmer. An initial stimulation amplitude setting of the stimulation program is limited to a minimal dose amplitude.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: March 28, 2023
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Dawn Gayle Flakne, Yarisa Jaroch Gonzalez, Alan Fryer, Lauren Kraiter
  • Patent number: 11612742
    Abstract: A method is provided for treating an intervertebral disc of a subject, the method including implanting at least one intra-pulposus exposed electrode surface in a nucleus pulposus of the intervertebral disc, and implanting one or more extra-pulposus exposed electrode surfaces outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry, while electrically coupled to the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces, is activated to drive fluid and introduce nutritional substances into the intervertebral disc, by applying a voltage between the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces. Other embodiments are also described.
    Type: Grant
    Filed: September 29, 2022
    Date of Patent: March 28, 2023
    Assignee: DISCURE TECHNOLOGIES LTD.
    Inventors: Yossi Gross, Gideon Fostick
  • Patent number: 11484706
    Abstract: Apparatus is provided for treating an intervertebral disc of a subject, the apparatus including: at least one intra-pulposus exposed electrode surface, which is configured to be implanted in a nucleus pulposus of the intervertebral disc; and one or more extra-pulposus exposed electrode surfaces, which are configured to be implanted outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry is electrically coupled to the at least one intra-pulposus exposed electrode surface and one or more extra-pulposus exposed electrode surfaces. The control circuitry is configured to drive fluid and introduce nutritional substances into the intervertebral disc, by applying a voltage between the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces. Other embodiments are also described.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: November 1, 2022
    Assignee: Discure Technologies Ltd
    Inventors: Yossi Gross, Gideon Fostick
  • Patent number: 11411408
    Abstract: A charging system in one aspect of the present disclosure includes a battery pack and a charger. The battery pack includes a battery and an information output circuit. The information output circuit outputs faulty state information in response to receiving a faulty state information request. The faulty state information indicates that the battery pack is in a first faulty state. The charger includes a charging power generation circuit, a charging control circuit, and a reception circuit. The charging control circuit transmits the faulty state information request. The reception circuit receives the faulty state information.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: August 9, 2022
    Assignee: MAKITA CORPORATION
    Inventors: Hisakazu Okabayashi, Yoshihiro Ishikawa
  • Patent number: 11383082
    Abstract: Described herein are techniques, devices, and systems for formulating, tracking, displaying, and using electrical muscle stimulation (EMS) intensity values that are meaningful and intuitive. Electrical impulses may be delivered via multiple electrodes of an EMS suit in accordance with pulse intensity settings, the pulse intensity settings comprising multiple channel intensity values associated with multiple channels. Each channel intensity value can be multiplied by a predefined number to generate displayable channel intensity values, and a global intensity value can be derived from the displayable channel intensity values. The global intensity value can be presented on a display, such as by presenting the global intensity value as a graphic overlaying media content featuring an instructor conducting a workout session.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: July 12, 2022
    Assignee: Katalyst Inc.
    Inventor: Björn Erich Woltermann
  • Patent number: 11123197
    Abstract: An artificial intervertebral disc (IVD) is provided for replacement of a degenerated intervertebral disc. The artificial IVD includes two endplates having oppositely-facing outward surfaces configured to engage respective intervertebral surfaces of the spinal column, and a chamber, which is disposed between oppositely-facing inner surfaces of the two endplates, and which includes a lateral wall including an electroosmotic membrane. A plurality of exposed electrode surface includes (i) one or more intra-chamber exposed electrode surfaces, which are located within the chamber; and (ii) one or more extra-chamber exposed electrode surfaces, which are located outside the chamber, in a vicinity of the chamber. Control circuitry is configured to drive at least one of the one or more intra-chamber exposed electrode surfaces and at least one of the one or more extra-chamber exposed electrode surfaces to electroosmotically drive liquid from outside the chamber to inside the chamber.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: September 21, 2021
    Assignee: RAINBOW MEDICAL LTD.
    Inventor: Yossi Gross
  • Patent number: 11005305
    Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: May 11, 2021
    Assignee: CIRTEC MEDICAL CORP.
    Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
  • Patent number: 10199884
    Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: February 5, 2019
    Assignee: Cirtec Medical Corp.
    Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
  • Patent number: 9950156
    Abstract: Apparatus is provided that includes at least one intra-pulposus exposed electrode surface, configured to be implanted in a nucleus pulposus of an intervertebral disc, and a plurality of extra-pulposus exposed electrode surfaces, configured to be implanted outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry is configured to separately control at least two of the plurality of extra-pulposus exposed electrode surfaces, and to repeatedly alternatively assume: (a) a pressure-increasing mode of operation, in which fluid is electroosmotically driven into the nucleus pulposus to increase pressure in the intervertebral disc, by applying a first mean voltage of less than 1.23 V between the exposed electrode surfaces, and (b) an oxygen-generating mode of operation, in which oxygen is generated within the nucleus pulposus by electrolysis, by applying a second mean voltage of at least 1.23 V between the exposed electrode surfaces. Other embodiments are also described.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: April 24, 2018
    Assignee: RAINBOW MEDICAL LTD.
    Inventors: Yossi Gross, Zev Sohn
  • Patent number: 9887574
    Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: February 6, 2018
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
  • Patent number: 9872986
    Abstract: Spinal cord stimulation (SCS) system having a recharging system with self alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsources, and IPG control through software on Smartphone/mobile device and tablet hardware during trial and permanent implants. SCS system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) providing concurrent, but unique stimulation fields. SCS system can include a replenishable power source, rechargeable using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery, can charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. A bi-directional telemetry link informs the patient or clinician the status of the system, including the state of charge of the IPG battery.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: January 23, 2018
    Assignee: Globus Medical, Inc.
    Inventors: Saif Khalil, Raghavendra Angara, Miles Curtis, Christopher Biele, Daniel Fellmeth
  • Patent number: 9802048
    Abstract: A method, system, and apparatus for providing a stimulation signal comprising a variable ramping portion using an implantable medical device (IMD). The first electrical comprises a first ramping portion. The first ramping portion comprises a first parameter and having a first value. The first electrical signal is applied to a target location of the patient's body. A second electrical signal comprising a second ramping portion is generated. The second ramping portion comprises the first parameter having a second value that is different from the first value. The second electrical signal is applied to a target location of the patient's body.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: October 31, 2017
    Assignee: CYBERONICS, INC.
    Inventor: Randolph K. Armstrong
  • Patent number: 8905948
    Abstract: The disclosure describes techniques for generation of proportional posture information over multiple time intervals. The techniques may include obtaining posture state data sensed by a medical device for a patient during delivery of therapy by the medical device, determining durations for which the patient occupied each of a plurality of posture states based on the posture state data, generating proportional posture information for a plurality of different time intervals based on the durations, wherein the proportional posture information for each of the time intervals indicates proportional amounts of the respective time interval in which the patient occupied the posture states, and presenting the proportional posture information to a user via a user interface.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: December 9, 2014
    Assignee: Medtronic, Inc.
    Inventors: Jon P. Davis, Dennis M. Skelton, Rajeev M. Sahasrabudhe, Shyam Gokaldas
  • Patent number: 8788056
    Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: July 22, 2014
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: John D. H. King, James R. Thacker
  • Patent number: 8677619
    Abstract: In one embodiment, a system for wrapping biomedical conductor wires about core material, comprises: a payout assembly and a take-up assembly for controllably paying out the core material and taking up the core material with the wrapped conductor wires; a turntable; a plurality of carriers, disposed on the turntable, for letting out the conductor wires; and a die for applying force to the conductor wires as the wires are wrapped about the core material, the die adapted to rotate according to group rotation of the plurality of carriers by the turntable during operation of the system, wherein the die comprises one or more features asymmetrically arranged about a circumference of the die, the one or more features adapted to direct the conductor wires from the plurality of carriers onto the core material in an axially repeating pattern of groups of closely spaced wires with each group separated by a distance larger than the spacing between adjacent wires within each group.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: March 25, 2014
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Don Dye, Paul Burros
  • Patent number: 8606358
    Abstract: An implantable medical device for treating the back of a patient. Stimulation energy is delivered to muscles or joint capsules or ligaments or nerve fibers to improve the heath of the back.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: December 10, 2013
    Assignee: Mainstay Medical Limited
    Inventor: Dan Sachs
  • Patent number: 8577469
    Abstract: Apparatus (10) is provided for treating an intervertebral disc (20) of a subject. The apparatus (10) includes a first electrode (30), configured to be inserted into a nucleus pulposus (40) of the disc (20), and a second electrode (32), configured to be placed outside of the nucleus pulposus (40), in a vicinity of the nucleus pulposus (40). A control unit (34) is configured to drive a current between the first and second electrodes (30, 32), and to configure the current to electroosmotically drive fluid between inside and outside the nucleus pulposus (40). Other embodiments are also described.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: November 5, 2013
    Assignee: Rainbow Medical Ltd.
    Inventor: Yossi Gross
  • Patent number: 8447412
    Abstract: An active implantable medical device having wireless communication of data via electrical pulses conducted by the interstitial tissues of the body. This device (12, 14) includes a pair of electrodes (22, 24) and generates pulse trains consisting of a series of electrical pulses applied to the electrodes. The pulse train is modulated by digital information (data) that is produced by the device. A regulated current or voltage source (42) is used to generate (44, 48) current or voltage pulses to form the pulse train. Each current or voltage pulse is a biphasic pulse comprising a positive and negative alternation. The biphasic current or voltage modulated by the digital information, is injected between the electrodes (22, 24) and wirelessly communicated.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: May 21, 2013
    Assignee: Sorin CRM S.A.S.
    Inventors: Renzo Dal Molin, Ashutosh Ghildiyal
  • Patent number: 8428728
    Abstract: An implantable medical device for treating the back of a patient. Stimulation energy is delivered to muscles or joint capsules or ligaments or nerve fibers to improve the heath of the back.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: April 23, 2013
    Assignee: Mainstay Medical Limited
    Inventor: Dan Sachs
  • Patent number: 8374697
    Abstract: Stimulation of bone growth to facilitate healing of a dental implant utilizing a interiorly threaded dental screw of nonconductive material in conjunction with a healing cap abutment whereby electrical stimulation facilitates healing of the surgical site. The device is powered by a battery for the purpose of creating an electrical-magnetic field to promote bone healing and bone formation. The electric magnetic field is directed to the bone around the device through a battery of a rechargeable type. A constant current is generated in a preferred range of about 5 ?A to about 20 ?A to stimulate bone healing and bone formation.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: February 12, 2013
    Inventor: J. Lee Berger
  • Patent number: 8359101
    Abstract: In one embodiment, a method electrically stimulates an area in a spinal disc. The method comprises: implanting at least one steerable lead at a placement site for stimulating a spinal disc such that the lead is disposed exterior and immediately adjacent to and circumferentially along an annulus of the spinal disc, the at least one lead including a plurality of electrodes distributed along a majority of a circumference of the annulus; connecting the lead to a signal generator; and generating electrical stimulation pulses using the generator to stimulate targeted portions of the spinal disc, wherein the stimulation of the targeted portion of the spinal disc sufficiently stimulates nerve tissue within the spinal disc to prevent communication of pain signals originating in the spinal disc without damaging tissue of the spinal disc.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: January 22, 2013
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Philip M. Finch, Scott F. Drees, John Erickson
  • Patent number: 8340771
    Abstract: According to one aspect, a method of treating a patient by electrically stimulating a predetermined site to treat a neurological condition. The method includes implanting a lead into subcutaneous tissue of the C2 dermatome/C3 dermatome area.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: December 25, 2012
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Mark Thimineur, Ed Kravitz, Peter Lando, Tracy Cameron, Rohan Hoare
  • Patent number: 8187179
    Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: May 29, 2012
    Assignee: NuVasive, Inc.
    Inventors: Patrick Miles, Scot Martinelli, Eric Finley, James Gharib, Allen Farquhar, Norbert Kaula, Jeffrey Blewett, Goretti Medeiros, legal representative
  • Publication number: 20120095522
    Abstract: A method for treatment of degenerative disc disease using capacitively coupled electrical stimulation. In one embodiment, a subject diagnosed as having degenerative disc disease is treated by placing first and second electrodes on the subject's body at the site of an identified disc in a state of degenerative disc disease, and applying an electric field to the identified disc via the first and second electrodes with the intent to treat the degenerative disc disease. The electric field is created with an electrical signal having a frequency within a range of 20 to 100 kHz and having a symmetrical waveform with an amplitude within a range of 0.1 to 20 volts peak-to-peak, preferably a frequency of approximately 60 kHz and an amplitude of approximately 5 volts peak-to-peak.
    Type: Application
    Filed: December 19, 2011
    Publication date: April 19, 2012
    Inventors: Bruce J. Simon, Jean C. Gan
  • Patent number: 8086317
    Abstract: In one embodiment, a method electrically stimulates an area in a spinal disc. The method comprises: implanting at least one steerable lead at a placement site for stimulating a spinal disc such that the lead is disposed exterior and immediately adjacent to and circumferentially along an annulus of the spinal disc, the at least one lead including a plurality of electrodes distributed along a majority of a circumference of the annulus; connecting the lead to a signal generator; and generating electrical stimulation pulses using the generator to stimulate targeted portions of the spinal disc, wherein the stimulation of the targeted portion of the spinal disc sufficiently stimulates nerve tissue within the spinal disc to prevent communication of pain signals originating in the spinal disc without damaging tissue of the spinal disc.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: December 27, 2011
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Philip M. Finch, Scott F. Drees, John Erickson
  • Patent number: 8082038
    Abstract: A method for treatment of degenerative disc disease using capacitively coupled electrical stimulation. In one embodiment, a subject diagnosed as having degenerative disc disease is treated by placing first and second electrodes on the subject's body at the site of an identified disc in a state of degenerative disc disease, and applying an electric field to the identified disc via the first and second electrodes with the intent to treat the degenerative disc disease. The electric field is created with an electrical signal having a frequency within a range of 20 to 100 kHz and having a symmetrical waveform with an amplitude within a range of 0.1 to 20 volts peak-to-peak, preferably a frequency of approximately 60 kHz and an amplitude of approximately 5 volts peak-to-peak.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: December 20, 2011
    Assignee: EBI, LLC
    Inventors: Bruce J. Simon, Jean C. Gan
  • Publication number: 20110230857
    Abstract: In accordance with some embodiments of the present invention, delivery systems and methods for delivering a substance in a medium is provided. The delivery system may include a delivery component, an electronic controller, one or more sensors, and a feedback mechanism. The delivery component has at least one reservoir that contains a substance (e.g., a liquid, a drug, etc.). The electronic controller is connected to the delivery component and controls the release of the substance from the at least one reservoir into the medium. The sensors monitor one or more parameters in the medium and provide a signal to a feedback mechanism. The feedback mechanism, in response to the signal, sends an electrical signal that directs the controller to release the substance from the reservoir into the medium, thereby maintaining a desire level of a monitored parameter (e.g., pH, pO2, temperature, pressure, ions, volume, impedance, dosage, biomarkers, etc.).
    Type: Application
    Filed: April 4, 2008
    Publication date: September 22, 2011
    Inventor: Ewa Herbst
  • Publication number: 20100280570
    Abstract: An apparatus (100) is described that comprises a generator unit (1) of generating electrical stimulation signals and a spinal cord stimulation unit (2) encompassing a plurality of stimulation contact surfaces (11-14) to which the generator unit (1) feeds the stimulation signals. At least two of the stimulation contact surfaces (11-14) are arranged in a staggered manner transverse to the direction in which the spinal cord extends.
    Type: Application
    Filed: October 28, 2008
    Publication date: November 4, 2010
    Inventors: Volker Sturm, Athanasios Koulousakis, Peter Tass
  • Patent number: 7738969
    Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: June 15, 2010
    Assignee: Baxano, Inc.
    Inventor: Jeffery L. Bleich
  • Patent number: 7738968
    Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.
    Type: Grant
    Filed: October 15, 2005
    Date of Patent: June 15, 2010
    Assignee: Baxano, Inc.
    Inventor: Jeffery L. Bleich
  • Publication number: 20100113884
    Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
    Type: Application
    Filed: December 30, 2009
    Publication date: May 6, 2010
    Inventors: Patrick Miles, Scot Martinelli, Eric Finley, James Gharib, Allen Farquhar, Norbert Kaula, Jeffrey Blewett, Goretti Medeiros
  • Patent number: 7682745
    Abstract: A medical device includes a rechargeable lithium-ion battery for providing power to the medical device. The lithium-ion battery includes a positive electrode comprising a current collector and an active material comprising a material selected from the group consisting of LiCoO2, LiMn2O4, LiNixCoyNi(1?x?y)O2, LiAlxCoyNi(1?x?y)O2, LiTixCoyNi(1?x?y)O2, and combinations thereof. The lithium-ion battery also includes a negative electrode having a current collector and an active material including a lithium titanate material. The current collector of the negative electrode includes a material selected from the group consisting of aluminum, titanium, and silver. The battery is configured for cycling to near-zero-voltage conditions without a substantial loss of battery capacity.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: March 23, 2010
    Assignee: Medtronic, Inc.
    Inventors: William G. Howard, Craig L. Schmidt, Erik R. Scott
  • Patent number: 7680542
    Abstract: The present invention is directed to a method of treating bone length discrepancies and angular deformities in a patient in need thereof, where the method involves radiofrequency ablation epiphysiodesis of a physeal plate. Specifically, the method treats long bone discrepancies with a minimally invasive procedure. The present invention is also directed to a method of inhibiting bone growth, where the method involves exposing a physeal growth plate to radiofrequency ablation epiphysiodesis.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: March 16, 2010
    Assignee: New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery
    Inventor: Roger Widmann
  • Patent number: 7574261
    Abstract: A method and device the may be employed for inhibiting bone growth, including inducing epiphysiodesis or hemiepiphysiodesis, by applying electrical current to a desired region. The device includes a power source and one or a series of electrodes for applying a current sufficient to reduce or stop the growth of a bone to selected regions of the bone. The method and device may be used to correct growth discrepancies in extremities such as the arms or legs, as well as correct the curvature of the spine in scoliosis patients.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: August 11, 2009
    Assignee: Nemours Biomedical Research
    Inventors: George R. Dodge, J. Richard Bowen
  • Patent number: 7555343
    Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.
    Type: Grant
    Filed: October 15, 2005
    Date of Patent: June 30, 2009
    Assignee: Baxano, Inc.
    Inventor: Jeffery L. Bleich
  • Patent number: 7519427
    Abstract: Quantity and time for medical operation are measured after starting the medical operation (step S1). Parameters in a parameter protection mode and parameters in a standard mode are compared so as to determine whether or not contents in the parameters coincide and whether or not five minutes passes (step S2). If five minutes do not pass, it is detected whether or not a power supply switch is turned off (step S4). If it is not turned off, the operation returns to the step S1 so as to determine whether or not the power supply is turned off within five minutes in steps S3 and S4 while measuring the quantity and the time for the medical operation. If five minutes passes without turning off the power supply, data for the quantity and the time for the medical operation are loaded in a memory (step S5). After that, the operation is completed.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: April 14, 2009
    Assignees: ITO Co., Ltd., Hirose Electric Co., Ltd.
    Inventors: Toshimasa Sakagami, Hirotsugu Sato, Takashi Nemoto
  • Patent number: 7496404
    Abstract: A spinal cord stimulation (SCS) system includes multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) which channels can provide concurrent, but unique stimulation fields, permitting virtual electrodes to be realized. The SCS system includes a replenishable power source (e.g., rechargeable battery), that may be recharged using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery can be used to charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. An included bi-directional telemetry link in the system informs the patient or clinician the status of the system, including the state of charge of the IPG battery. Other processing circuitry in the IPG allows electrode impedance measurements to be made. Further circuitry in the external battery charger can provide alignment detection for the coil pairs.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: February 24, 2009
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Paul M Meadows, Carla M Woods, David K Peterson, Joey Chen, David H Payne
  • Publication number: 20080300591
    Abstract: In a discectomy method one removes at least a substantial portion of a spinal disc. Thereafter one operates an ultrasonic instrument to level opposing faces of vertebrae on opposite sides of the removed spinal disc. Graft or synthetic disc material is inserted between the vertebrae so that the graft or synthetic disc material is in contact with the leveled opposing faces. In an associated nucleotomy, a cannulated probe is inserted into a spinal disc and used to remove the nucleus pulposus. A synthetic or substitute nucleus material may then be inserted into the evacuated annulus.
    Type: Application
    Filed: June 1, 2007
    Publication date: December 4, 2008
    Applicant: MISONIX, INCORPORATED
    Inventors: Alexander L. Darian, Dan Voic, Ronald R. Manna
  • Patent number: 7295876
    Abstract: A system, method, and computer program product for interactively defining and calibrating a treatment protocol program for a stimulation device such as an implantable pulse generator (IPG). An IPG, whether it is a self-contained implantable pulse generator (SCIPG) or externally-powered implantable pulse generator (EPIPG), communicates with an external patient programmer (EPP) to receive treatment protocol programs. Using the EPP, treatment protocol programs are developed, executed, and tested while the patient provides real-time feedback, providing efficient and effective programming.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: November 13, 2007
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: John H. Erickson
  • Patent number: 7206638
    Abstract: A method and device is disclosed for inhibiting bone growth, including inducing epiphysiodesis or hemiepiphysiodesis, using electrical current. The device includes a power source and one or a series of electrodes for applying a current sufficient to reduce or stop the growth of a bone to selected regions of the bone. The method and device may be used to correct growth discrepancies in extremities such as the arms or legs, as well as correct the curvature of the spine in scoliosis patients.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: April 17, 2007
    Assignee: The Nemours Foundation
    Inventors: George R. Dodge, J. Richard Bowen
  • Patent number: 7187976
    Abstract: A multi-purpose FES system includes a multi-function, implantable stimulator for stimulating different sites in a patient's body. The stimulator includes a control unit and a receiving device. The stimulator further has a plurality of bundles of electric leads connected to the control unit, each lead terminating in at least one electrode to provide a plurality of discrete groups of electrodes associated with each site. Each group of electrodes is operable to stimulate its associated site in the patient's body, under the action of stimulation signals from the control unit, the control unit receiving signals from the receiving device. A transmitter is arranged externally of the patient's body for supplying signals transcutaneously to the receiving device of the stimulator. A controller is in communication with the transmitter via a communications interface unit.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: March 6, 2007
    Assignee: Neopraxis Pty Ltd.
    Inventors: Michael Duncan, Ian Bruinsma, Zoran Milijasevic, Andrew Barriskill
  • Patent number: 7177691
    Abstract: An implantable medical device, such as an implantable pulse generator (IPG) used with a spinal cord stimulation (SCS) system, includes a rechargeable lithiumion battery having an anode electrode with a substrate made substantially from titanium. Such battery construction allows the rechargeable battery to be discharged down to zero volts without damage to the battery. The implantable medical device includes battery charging and protection circuitry that controls the charging of the battery so as to assure its reliable and safe operation. A multi-rate charge algorithm is employed that minimizes charging time while ensuring the battery cell is safely charged. Fast charging occurs at safer lower battery voltages (e.g., battery voltage above about 2.5 V), and slower charging occurs when the battery nears full charge higher battery voltages (e.g., above about 4.0 V). When potentially less-than-safe very low voltages are encountered (e.g., less than 2.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: February 13, 2007
    Assignee: Advanced Bionics Corporation
    Inventors: Paul M Meadows, Carla Mann Woods, Hisashi Tsukamoto, Joey Chen
  • Patent number: 7167753
    Abstract: A technique and associated device for stimulating multiple electrodes with multiple electrical signals in multiple regions of the spine without injury to the patient. The electrodes are applied to respective sides of the patient's spine, and a first electrical signal is applied to any electrodes in a treatment area of the lumbar region of the patient's spine, a second electrical signal is applied to any electrodes in a treatment area of the thoracic region of the patient's spine, and a third electrical signal is applied to any electrodes in a treatment area of the cervical region of the patient's spine to induce osteogenesis in at least one of the respective treated area's of the patient's spine. The first, second, and third electrical signals respectively generate different electrode currents in the respective treated areas and are ideally selected to create current densities that are approximately equal in respective treatment areas.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: January 23, 2007
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Carl T Brighton, Solomon R Pollack
  • Patent number: 7158835
    Abstract: A technique and device for preventing and/or treating osteoporosis, hip and spine fractures, and/or spine fusions by incorporating at least one conductive coil (110) into a garment (90) adapted to be worn adjacent to the patient's skin over a treatment area and applying an electrical signal to the coil effective to produce a magnetic flux the penetrates the treatment area so as to produce an electric field in the bones and the treatment area.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: January 2, 2007
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Carl T. Brighton, Solomon R. Pollack
  • Publication number: 20040220621
    Abstract: A method and apparatus for delivering corrective therapy through hormone regulation is provided. Inhibition of sympathetic fibers by spinal cord stimulation is used to regulate the levels of hormones such as catecholamines, renin, and calcitonin gene-related peptide. The invention utilizes a closed or open loop feedback system in which physiological parameters such as the concentrations of hormones and sympathetic indicators such as heart rate and urine production are monitored and used to determine the appropriate level of neurostimulation.
    Type: Application
    Filed: April 30, 2003
    Publication date: November 4, 2004
    Inventors: Xiaohong Zhou, Thomas J. Mullen, Gary W. King, Michael R.S. Hill
  • Publication number: 20040172093
    Abstract: In one aspect the present disclosure provides a method of rehabilitating a person who has suffered spinal cord damage including the steps of providing exercise equipment capable of exercising a person's limbs, providing functional electrical stimulation to the person's limbs to be exercised in order to operate the exercise equipment, reducing the level of functional electrical stimulation as the person's muscles tire, decreasing a resistance provided by the exercise equipment or providing assistance to maintain an acceptable speed of the exercise equipment, and completely removing functional electrical stimulation to the person's limbs and providing assistance to maintain an acceptable speed of the exercise equipment. Also provided are apparatus to carry out the method.
    Type: Application
    Filed: January 31, 2003
    Publication date: September 2, 2004
    Inventor: Patrick D. Rummerfield
  • Publication number: 20040111118
    Abstract: A method of performing a medical procedure, such as surgery, is provided. The spinal cord is stimulated in order to control at least one physiological function. The medical procedure is performed and stimulation of the spinal cord is stopped.
    Type: Application
    Filed: November 19, 2003
    Publication date: June 10, 2004
    Inventors: Michael R.S. Hill, Scott E. Jahns, James R. Keogh
  • Publication number: 20040059394
    Abstract: A stimulator and a method for electrical stimulation of bone to promote osteogenesis is disclosed in which surface electrodes positioned around an incision site transmit an interferential current that has a base medium frequency alternating current between 1K-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate two circuits for use in producing the interferential current. The effective area of stimulation is controlled by placement of electrodes and electrode orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation.
    Type: Application
    Filed: August 1, 2003
    Publication date: March 25, 2004
    Inventors: William J. Carroll, Michael B. McGraw, William A. Rux