Correcting Spinal Deformities Patents (Class 607/43)
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Patent number: 11931572Abstract: A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.Type: GrantFiled: December 24, 2020Date of Patent: March 19, 2024Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Simeng Zhang, Hyun-Joo Park, Erika Ross
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Patent number: 11872394Abstract: Described herein are systems and methods for the treatment of pain using electrical nerve conduction block (ENCB). Contrary to other methods of pain treatment, the ENCB can establish a direct block of neural activity, thereby eliminating the pain. Additionally, the ENCB can be administered without causing electrochemical damage. An example method can include: placing at least one electrode contact in electrical communication with a region of a subject's spinal cord; applying an electrical nerve conduction block (ENCB) to a nerve in the region through the at least one electrode contact; and blocking neural activity with the ENCB to reduce the pain or other unwanted sensation in the subject.Type: GrantFiled: May 13, 2021Date of Patent: January 16, 2024Assignees: CASE WESTERN RESERVE UNIVERAITY, NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENTInventors: Niloy Bhadra, Narendra Bhadra, Kevin L Kilgore, Scott Lempka, Jesse Wainright, Tina Vrabec, Manfred Franke
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Patent number: 11612742Abstract: A method is provided for treating an intervertebral disc of a subject, the method including implanting at least one intra-pulposus exposed electrode surface in a nucleus pulposus of the intervertebral disc, and implanting one or more extra-pulposus exposed electrode surfaces outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry, while electrically coupled to the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces, is activated to drive fluid and introduce nutritional substances into the intervertebral disc, by applying a voltage between the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces. Other embodiments are also described.Type: GrantFiled: September 29, 2022Date of Patent: March 28, 2023Assignee: DISCURE TECHNOLOGIES LTD.Inventors: Yossi Gross, Gideon Fostick
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Patent number: 11612753Abstract: A method for remote programming a therapy device for neurostimulation comprises: generating a stimulation program for the therapy device by means of a clinician programmer; transferring the stimulation program to a patient programmer; loading the stimulation program on the therapy device from the patient programmer; and increasing a stimulation amplitude of the stimulation program by means of the patient programmer. An initial stimulation amplitude setting of the stimulation program is limited to a minimal dose amplitude.Type: GrantFiled: August 2, 2019Date of Patent: March 28, 2023Assignee: BIOTRONIK SE & Co. KGInventors: Dawn Gayle Flakne, Yarisa Jaroch Gonzalez, Alan Fryer, Lauren Kraiter
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Patent number: 11484706Abstract: Apparatus is provided for treating an intervertebral disc of a subject, the apparatus including: at least one intra-pulposus exposed electrode surface, which is configured to be implanted in a nucleus pulposus of the intervertebral disc; and one or more extra-pulposus exposed electrode surfaces, which are configured to be implanted outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry is electrically coupled to the at least one intra-pulposus exposed electrode surface and one or more extra-pulposus exposed electrode surfaces. The control circuitry is configured to drive fluid and introduce nutritional substances into the intervertebral disc, by applying a voltage between the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces. Other embodiments are also described.Type: GrantFiled: August 2, 2021Date of Patent: November 1, 2022Assignee: Discure Technologies LtdInventors: Yossi Gross, Gideon Fostick
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Patent number: 11411408Abstract: A charging system in one aspect of the present disclosure includes a battery pack and a charger. The battery pack includes a battery and an information output circuit. The information output circuit outputs faulty state information in response to receiving a faulty state information request. The faulty state information indicates that the battery pack is in a first faulty state. The charger includes a charging power generation circuit, a charging control circuit, and a reception circuit. The charging control circuit transmits the faulty state information request. The reception circuit receives the faulty state information.Type: GrantFiled: December 13, 2019Date of Patent: August 9, 2022Assignee: MAKITA CORPORATIONInventors: Hisakazu Okabayashi, Yoshihiro Ishikawa
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Patent number: 11383082Abstract: Described herein are techniques, devices, and systems for formulating, tracking, displaying, and using electrical muscle stimulation (EMS) intensity values that are meaningful and intuitive. Electrical impulses may be delivered via multiple electrodes of an EMS suit in accordance with pulse intensity settings, the pulse intensity settings comprising multiple channel intensity values associated with multiple channels. Each channel intensity value can be multiplied by a predefined number to generate displayable channel intensity values, and a global intensity value can be derived from the displayable channel intensity values. The global intensity value can be presented on a display, such as by presenting the global intensity value as a graphic overlaying media content featuring an instructor conducting a workout session.Type: GrantFiled: June 25, 2020Date of Patent: July 12, 2022Assignee: Katalyst Inc.Inventor: Björn Erich Woltermann
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Patent number: 11123197Abstract: An artificial intervertebral disc (IVD) is provided for replacement of a degenerated intervertebral disc. The artificial IVD includes two endplates having oppositely-facing outward surfaces configured to engage respective intervertebral surfaces of the spinal column, and a chamber, which is disposed between oppositely-facing inner surfaces of the two endplates, and which includes a lateral wall including an electroosmotic membrane. A plurality of exposed electrode surface includes (i) one or more intra-chamber exposed electrode surfaces, which are located within the chamber; and (ii) one or more extra-chamber exposed electrode surfaces, which are located outside the chamber, in a vicinity of the chamber. Control circuitry is configured to drive at least one of the one or more intra-chamber exposed electrode surfaces and at least one of the one or more extra-chamber exposed electrode surfaces to electroosmotically drive liquid from outside the chamber to inside the chamber.Type: GrantFiled: September 3, 2019Date of Patent: September 21, 2021Assignee: RAINBOW MEDICAL LTD.Inventor: Yossi Gross
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Patent number: 11005305Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.Type: GrantFiled: February 4, 2019Date of Patent: May 11, 2021Assignee: CIRTEC MEDICAL CORP.Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
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Patent number: 10199884Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.Type: GrantFiled: December 22, 2017Date of Patent: February 5, 2019Assignee: Cirtec Medical Corp.Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
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Patent number: 9950156Abstract: Apparatus is provided that includes at least one intra-pulposus exposed electrode surface, configured to be implanted in a nucleus pulposus of an intervertebral disc, and a plurality of extra-pulposus exposed electrode surfaces, configured to be implanted outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry is configured to separately control at least two of the plurality of extra-pulposus exposed electrode surfaces, and to repeatedly alternatively assume: (a) a pressure-increasing mode of operation, in which fluid is electroosmotically driven into the nucleus pulposus to increase pressure in the intervertebral disc, by applying a first mean voltage of less than 1.23 V between the exposed electrode surfaces, and (b) an oxygen-generating mode of operation, in which oxygen is generated within the nucleus pulposus by electrolysis, by applying a second mean voltage of at least 1.23 V between the exposed electrode surfaces. Other embodiments are also described.Type: GrantFiled: September 13, 2016Date of Patent: April 24, 2018Assignee: RAINBOW MEDICAL LTD.Inventors: Yossi Gross, Zev Sohn
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Patent number: 9887574Abstract: A wireless charger for automatically tuning an optimum frequency to inductively charge a rechargeable battery of an implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body is provided. The charging coil in the charger is wirelessly coupled to a receiving coil of the IPG to charge the rechargeable battery. An optimization circuit detects a reflected impedance of the charging coil through a reflected impedance sensor, and select an optimum frequency of a charging signal supplied to the charging coil based on the detected reflected impedances of a plurality of charging frequencies in a selected frequency range. Advantageously, the optimum charging frequency provides a more efficient way to charge the IPG's rechargeable battery.Type: GrantFiled: March 10, 2015Date of Patent: February 6, 2018Assignee: GLOBUS MEDICAL, INC.Inventors: Raghavendra Angara, Saif Khalil, Miles Curtis, Christopher Biele, Daniel Fellmeth
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Patent number: 9872986Abstract: Spinal cord stimulation (SCS) system having a recharging system with self alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsources, and IPG control through software on Smartphone/mobile device and tablet hardware during trial and permanent implants. SCS system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) providing concurrent, but unique stimulation fields. SCS system can include a replenishable power source, rechargeable using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery, can charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. A bi-directional telemetry link informs the patient or clinician the status of the system, including the state of charge of the IPG battery.Type: GrantFiled: August 3, 2016Date of Patent: January 23, 2018Assignee: Globus Medical, Inc.Inventors: Saif Khalil, Raghavendra Angara, Miles Curtis, Christopher Biele, Daniel Fellmeth
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Patent number: 9802048Abstract: A method, system, and apparatus for providing a stimulation signal comprising a variable ramping portion using an implantable medical device (IMD). The first electrical comprises a first ramping portion. The first ramping portion comprises a first parameter and having a first value. The first electrical signal is applied to a target location of the patient's body. A second electrical signal comprising a second ramping portion is generated. The second ramping portion comprises the first parameter having a second value that is different from the first value. The second electrical signal is applied to a target location of the patient's body.Type: GrantFiled: February 27, 2014Date of Patent: October 31, 2017Assignee: CYBERONICS, INC.Inventor: Randolph K. Armstrong
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Patent number: 8905948Abstract: The disclosure describes techniques for generation of proportional posture information over multiple time intervals. The techniques may include obtaining posture state data sensed by a medical device for a patient during delivery of therapy by the medical device, determining durations for which the patient occupied each of a plurality of posture states based on the posture state data, generating proportional posture information for a plurality of different time intervals based on the durations, wherein the proportional posture information for each of the time intervals indicates proportional amounts of the respective time interval in which the patient occupied the posture states, and presenting the proportional posture information to a user via a user interface.Type: GrantFiled: October 31, 2012Date of Patent: December 9, 2014Assignee: Medtronic, Inc.Inventors: Jon P. Davis, Dennis M. Skelton, Rajeev M. Sahasrabudhe, Shyam Gokaldas
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Patent number: 8788056Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.Type: GrantFiled: August 16, 2013Date of Patent: July 22, 2014Assignee: Boston Scientific Neuromodulation CorporationInventors: John D. H. King, James R. Thacker
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Patent number: 8677619Abstract: In one embodiment, a system for wrapping biomedical conductor wires about core material, comprises: a payout assembly and a take-up assembly for controllably paying out the core material and taking up the core material with the wrapped conductor wires; a turntable; a plurality of carriers, disposed on the turntable, for letting out the conductor wires; and a die for applying force to the conductor wires as the wires are wrapped about the core material, the die adapted to rotate according to group rotation of the plurality of carriers by the turntable during operation of the system, wherein the die comprises one or more features asymmetrically arranged about a circumference of the die, the one or more features adapted to direct the conductor wires from the plurality of carriers onto the core material in an axially repeating pattern of groups of closely spaced wires with each group separated by a distance larger than the spacing between adjacent wires within each group.Type: GrantFiled: September 30, 2010Date of Patent: March 25, 2014Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Don Dye, Paul Burros
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Patent number: 8606358Abstract: An implantable medical device for treating the back of a patient. Stimulation energy is delivered to muscles or joint capsules or ligaments or nerve fibers to improve the heath of the back.Type: GrantFiled: April 8, 2013Date of Patent: December 10, 2013Assignee: Mainstay Medical LimitedInventor: Dan Sachs
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Patent number: 8577469Abstract: Apparatus (10) is provided for treating an intervertebral disc (20) of a subject. The apparatus (10) includes a first electrode (30), configured to be inserted into a nucleus pulposus (40) of the disc (20), and a second electrode (32), configured to be placed outside of the nucleus pulposus (40), in a vicinity of the nucleus pulposus (40). A control unit (34) is configured to drive a current between the first and second electrodes (30, 32), and to configure the current to electroosmotically drive fluid between inside and outside the nucleus pulposus (40). Other embodiments are also described.Type: GrantFiled: July 10, 2007Date of Patent: November 5, 2013Assignee: Rainbow Medical Ltd.Inventor: Yossi Gross
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Patent number: 8447412Abstract: An active implantable medical device having wireless communication of data via electrical pulses conducted by the interstitial tissues of the body. This device (12, 14) includes a pair of electrodes (22, 24) and generates pulse trains consisting of a series of electrical pulses applied to the electrodes. The pulse train is modulated by digital information (data) that is produced by the device. A regulated current or voltage source (42) is used to generate (44, 48) current or voltage pulses to form the pulse train. Each current or voltage pulse is a biphasic pulse comprising a positive and negative alternation. The biphasic current or voltage modulated by the digital information, is injected between the electrodes (22, 24) and wirelessly communicated.Type: GrantFiled: September 26, 2011Date of Patent: May 21, 2013Assignee: Sorin CRM S.A.S.Inventors: Renzo Dal Molin, Ashutosh Ghildiyal
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Patent number: 8428728Abstract: An implantable medical device for treating the back of a patient. Stimulation energy is delivered to muscles or joint capsules or ligaments or nerve fibers to improve the heath of the back.Type: GrantFiled: March 10, 2008Date of Patent: April 23, 2013Assignee: Mainstay Medical LimitedInventor: Dan Sachs
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Patent number: 8374697Abstract: Stimulation of bone growth to facilitate healing of a dental implant utilizing a interiorly threaded dental screw of nonconductive material in conjunction with a healing cap abutment whereby electrical stimulation facilitates healing of the surgical site. The device is powered by a battery for the purpose of creating an electrical-magnetic field to promote bone healing and bone formation. The electric magnetic field is directed to the bone around the device through a battery of a rechargeable type. A constant current is generated in a preferred range of about 5 ?A to about 20 ?A to stimulate bone healing and bone formation.Type: GrantFiled: February 4, 2010Date of Patent: February 12, 2013Inventor: J. Lee Berger
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Patent number: 8359101Abstract: In one embodiment, a method electrically stimulates an area in a spinal disc. The method comprises: implanting at least one steerable lead at a placement site for stimulating a spinal disc such that the lead is disposed exterior and immediately adjacent to and circumferentially along an annulus of the spinal disc, the at least one lead including a plurality of electrodes distributed along a majority of a circumference of the annulus; connecting the lead to a signal generator; and generating electrical stimulation pulses using the generator to stimulate targeted portions of the spinal disc, wherein the stimulation of the targeted portion of the spinal disc sufficiently stimulates nerve tissue within the spinal disc to prevent communication of pain signals originating in the spinal disc without damaging tissue of the spinal disc.Type: GrantFiled: December 23, 2011Date of Patent: January 22, 2013Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Philip M. Finch, Scott F. Drees, John Erickson
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Patent number: 8340771Abstract: According to one aspect, a method of treating a patient by electrically stimulating a predetermined site to treat a neurological condition. The method includes implanting a lead into subcutaneous tissue of the C2 dermatome/C3 dermatome area.Type: GrantFiled: April 19, 2010Date of Patent: December 25, 2012Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Mark Thimineur, Ed Kravitz, Peter Lando, Tracy Cameron, Rohan Hoare
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Patent number: 8187179Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.Type: GrantFiled: December 30, 2009Date of Patent: May 29, 2012Assignee: NuVasive, Inc.Inventors: Patrick Miles, Scot Martinelli, Eric Finley, James Gharib, Allen Farquhar, Norbert Kaula, Jeffrey Blewett, Goretti Medeiros, legal representative
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Publication number: 20120095522Abstract: A method for treatment of degenerative disc disease using capacitively coupled electrical stimulation. In one embodiment, a subject diagnosed as having degenerative disc disease is treated by placing first and second electrodes on the subject's body at the site of an identified disc in a state of degenerative disc disease, and applying an electric field to the identified disc via the first and second electrodes with the intent to treat the degenerative disc disease. The electric field is created with an electrical signal having a frequency within a range of 20 to 100 kHz and having a symmetrical waveform with an amplitude within a range of 0.1 to 20 volts peak-to-peak, preferably a frequency of approximately 60 kHz and an amplitude of approximately 5 volts peak-to-peak.Type: ApplicationFiled: December 19, 2011Publication date: April 19, 2012Inventors: Bruce J. Simon, Jean C. Gan
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Patent number: 8086317Abstract: In one embodiment, a method electrically stimulates an area in a spinal disc. The method comprises: implanting at least one steerable lead at a placement site for stimulating a spinal disc such that the lead is disposed exterior and immediately adjacent to and circumferentially along an annulus of the spinal disc, the at least one lead including a plurality of electrodes distributed along a majority of a circumference of the annulus; connecting the lead to a signal generator; and generating electrical stimulation pulses using the generator to stimulate targeted portions of the spinal disc, wherein the stimulation of the targeted portion of the spinal disc sufficiently stimulates nerve tissue within the spinal disc to prevent communication of pain signals originating in the spinal disc without damaging tissue of the spinal disc.Type: GrantFiled: November 2, 2010Date of Patent: December 27, 2011Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Philip M. Finch, Scott F. Drees, John Erickson
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Patent number: 8082038Abstract: A method for treatment of degenerative disc disease using capacitively coupled electrical stimulation. In one embodiment, a subject diagnosed as having degenerative disc disease is treated by placing first and second electrodes on the subject's body at the site of an identified disc in a state of degenerative disc disease, and applying an electric field to the identified disc via the first and second electrodes with the intent to treat the degenerative disc disease. The electric field is created with an electrical signal having a frequency within a range of 20 to 100 kHz and having a symmetrical waveform with an amplitude within a range of 0.1 to 20 volts peak-to-peak, preferably a frequency of approximately 60 kHz and an amplitude of approximately 5 volts peak-to-peak.Type: GrantFiled: July 7, 2005Date of Patent: December 20, 2011Assignee: EBI, LLCInventors: Bruce J. Simon, Jean C. Gan
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Publication number: 20110230857Abstract: In accordance with some embodiments of the present invention, delivery systems and methods for delivering a substance in a medium is provided. The delivery system may include a delivery component, an electronic controller, one or more sensors, and a feedback mechanism. The delivery component has at least one reservoir that contains a substance (e.g., a liquid, a drug, etc.). The electronic controller is connected to the delivery component and controls the release of the substance from the at least one reservoir into the medium. The sensors monitor one or more parameters in the medium and provide a signal to a feedback mechanism. The feedback mechanism, in response to the signal, sends an electrical signal that directs the controller to release the substance from the reservoir into the medium, thereby maintaining a desire level of a monitored parameter (e.g., pH, pO2, temperature, pressure, ions, volume, impedance, dosage, biomarkers, etc.).Type: ApplicationFiled: April 4, 2008Publication date: September 22, 2011Inventor: Ewa Herbst
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Publication number: 20100280570Abstract: An apparatus (100) is described that comprises a generator unit (1) of generating electrical stimulation signals and a spinal cord stimulation unit (2) encompassing a plurality of stimulation contact surfaces (11-14) to which the generator unit (1) feeds the stimulation signals. At least two of the stimulation contact surfaces (11-14) are arranged in a staggered manner transverse to the direction in which the spinal cord extends.Type: ApplicationFiled: October 28, 2008Publication date: November 4, 2010Inventors: Volker Sturm, Athanasios Koulousakis, Peter Tass
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Patent number: 7738968Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.Type: GrantFiled: October 15, 2005Date of Patent: June 15, 2010Assignee: Baxano, Inc.Inventor: Jeffery L. Bleich
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Patent number: 7738969Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.Type: GrantFiled: January 21, 2009Date of Patent: June 15, 2010Assignee: Baxano, Inc.Inventor: Jeffery L. Bleich
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Publication number: 20100113884Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.Type: ApplicationFiled: December 30, 2009Publication date: May 6, 2010Inventors: Patrick Miles, Scot Martinelli, Eric Finley, James Gharib, Allen Farquhar, Norbert Kaula, Jeffrey Blewett, Goretti Medeiros
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Patent number: 7682745Abstract: A medical device includes a rechargeable lithium-ion battery for providing power to the medical device. The lithium-ion battery includes a positive electrode comprising a current collector and an active material comprising a material selected from the group consisting of LiCoO2, LiMn2O4, LiNixCoyNi(1?x?y)O2, LiAlxCoyNi(1?x?y)O2, LiTixCoyNi(1?x?y)O2, and combinations thereof. The lithium-ion battery also includes a negative electrode having a current collector and an active material including a lithium titanate material. The current collector of the negative electrode includes a material selected from the group consisting of aluminum, titanium, and silver. The battery is configured for cycling to near-zero-voltage conditions without a substantial loss of battery capacity.Type: GrantFiled: October 29, 2004Date of Patent: March 23, 2010Assignee: Medtronic, Inc.Inventors: William G. Howard, Craig L. Schmidt, Erik R. Scott
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Patent number: 7680542Abstract: The present invention is directed to a method of treating bone length discrepancies and angular deformities in a patient in need thereof, where the method involves radiofrequency ablation epiphysiodesis of a physeal plate. Specifically, the method treats long bone discrepancies with a minimally invasive procedure. The present invention is also directed to a method of inhibiting bone growth, where the method involves exposing a physeal growth plate to radiofrequency ablation epiphysiodesis.Type: GrantFiled: May 17, 2005Date of Patent: March 16, 2010Assignee: New York Society for the Ruptured and Crippled Maintaining the Hospital for Special SurgeryInventor: Roger Widmann
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Patent number: 7574261Abstract: A method and device the may be employed for inhibiting bone growth, including inducing epiphysiodesis or hemiepiphysiodesis, by applying electrical current to a desired region. The device includes a power source and one or a series of electrodes for applying a current sufficient to reduce or stop the growth of a bone to selected regions of the bone. The method and device may be used to correct growth discrepancies in extremities such as the arms or legs, as well as correct the curvature of the spine in scoliosis patients.Type: GrantFiled: May 24, 2006Date of Patent: August 11, 2009Assignee: Nemours Biomedical ResearchInventors: George R. Dodge, J. Richard Bowen
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Patent number: 7555343Abstract: Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.Type: GrantFiled: October 15, 2005Date of Patent: June 30, 2009Assignee: Baxano, Inc.Inventor: Jeffery L. Bleich
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Patent number: 7519427Abstract: Quantity and time for medical operation are measured after starting the medical operation (step S1). Parameters in a parameter protection mode and parameters in a standard mode are compared so as to determine whether or not contents in the parameters coincide and whether or not five minutes passes (step S2). If five minutes do not pass, it is detected whether or not a power supply switch is turned off (step S4). If it is not turned off, the operation returns to the step S1 so as to determine whether or not the power supply is turned off within five minutes in steps S3 and S4 while measuring the quantity and the time for the medical operation. If five minutes passes without turning off the power supply, data for the quantity and the time for the medical operation are loaded in a memory (step S5). After that, the operation is completed.Type: GrantFiled: May 12, 2004Date of Patent: April 14, 2009Assignees: ITO Co., Ltd., Hirose Electric Co., Ltd.Inventors: Toshimasa Sakagami, Hirotsugu Sato, Takashi Nemoto
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Patent number: 7496404Abstract: A spinal cord stimulation (SCS) system includes multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) which channels can provide concurrent, but unique stimulation fields, permitting virtual electrodes to be realized. The SCS system includes a replenishable power source (e.g., rechargeable battery), that may be recharged using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery can be used to charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. An included bi-directional telemetry link in the system informs the patient or clinician the status of the system, including the state of charge of the IPG battery. Other processing circuitry in the IPG allows electrode impedance measurements to be made. Further circuitry in the external battery charger can provide alignment detection for the coil pairs.Type: GrantFiled: December 10, 2004Date of Patent: February 24, 2009Assignee: Boston Scientific Neuromodulation CorporationInventors: Paul M Meadows, Carla M Woods, David K Peterson, Joey Chen, David H Payne
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Publication number: 20080300591Abstract: In a discectomy method one removes at least a substantial portion of a spinal disc. Thereafter one operates an ultrasonic instrument to level opposing faces of vertebrae on opposite sides of the removed spinal disc. Graft or synthetic disc material is inserted between the vertebrae so that the graft or synthetic disc material is in contact with the leveled opposing faces. In an associated nucleotomy, a cannulated probe is inserted into a spinal disc and used to remove the nucleus pulposus. A synthetic or substitute nucleus material may then be inserted into the evacuated annulus.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Applicant: MISONIX, INCORPORATEDInventors: Alexander L. Darian, Dan Voic, Ronald R. Manna
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Patent number: 7295876Abstract: A system, method, and computer program product for interactively defining and calibrating a treatment protocol program for a stimulation device such as an implantable pulse generator (IPG). An IPG, whether it is a self-contained implantable pulse generator (SCIPG) or externally-powered implantable pulse generator (EPIPG), communicates with an external patient programmer (EPP) to receive treatment protocol programs. Using the EPP, treatment protocol programs are developed, executed, and tested while the patient provides real-time feedback, providing efficient and effective programming.Type: GrantFiled: March 4, 2005Date of Patent: November 13, 2007Assignee: Advanced Neuromodulation Systems, Inc.Inventor: John H. Erickson
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Patent number: 7206638Abstract: A method and device is disclosed for inhibiting bone growth, including inducing epiphysiodesis or hemiepiphysiodesis, using electrical current. The device includes a power source and one or a series of electrodes for applying a current sufficient to reduce or stop the growth of a bone to selected regions of the bone. The method and device may be used to correct growth discrepancies in extremities such as the arms or legs, as well as correct the curvature of the spine in scoliosis patients.Type: GrantFiled: November 20, 2003Date of Patent: April 17, 2007Assignee: The Nemours FoundationInventors: George R. Dodge, J. Richard Bowen
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Patent number: 7187976Abstract: A multi-purpose FES system includes a multi-function, implantable stimulator for stimulating different sites in a patient's body. The stimulator includes a control unit and a receiving device. The stimulator further has a plurality of bundles of electric leads connected to the control unit, each lead terminating in at least one electrode to provide a plurality of discrete groups of electrodes associated with each site. Each group of electrodes is operable to stimulate its associated site in the patient's body, under the action of stimulation signals from the control unit, the control unit receiving signals from the receiving device. A transmitter is arranged externally of the patient's body for supplying signals transcutaneously to the receiving device of the stimulator. A controller is in communication with the transmitter via a communications interface unit.Type: GrantFiled: January 17, 2003Date of Patent: March 6, 2007Assignee: Neopraxis Pty Ltd.Inventors: Michael Duncan, Ian Bruinsma, Zoran Milijasevic, Andrew Barriskill
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Patent number: 7177691Abstract: An implantable medical device, such as an implantable pulse generator (IPG) used with a spinal cord stimulation (SCS) system, includes a rechargeable lithiumion battery having an anode electrode with a substrate made substantially from titanium. Such battery construction allows the rechargeable battery to be discharged down to zero volts without damage to the battery. The implantable medical device includes battery charging and protection circuitry that controls the charging of the battery so as to assure its reliable and safe operation. A multi-rate charge algorithm is employed that minimizes charging time while ensuring the battery cell is safely charged. Fast charging occurs at safer lower battery voltages (e.g., battery voltage above about 2.5 V), and slower charging occurs when the battery nears full charge higher battery voltages (e.g., above about 4.0 V). When potentially less-than-safe very low voltages are encountered (e.g., less than 2.Type: GrantFiled: April 18, 2003Date of Patent: February 13, 2007Assignee: Advanced Bionics CorporationInventors: Paul M Meadows, Carla Mann Woods, Hisashi Tsukamoto, Joey Chen
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Patent number: 7167753Abstract: A technique and associated device for stimulating multiple electrodes with multiple electrical signals in multiple regions of the spine without injury to the patient. The electrodes are applied to respective sides of the patient's spine, and a first electrical signal is applied to any electrodes in a treatment area of the lumbar region of the patient's spine, a second electrical signal is applied to any electrodes in a treatment area of the thoracic region of the patient's spine, and a third electrical signal is applied to any electrodes in a treatment area of the cervical region of the patient's spine to induce osteogenesis in at least one of the respective treated area's of the patient's spine. The first, second, and third electrical signals respectively generate different electrode currents in the respective treated areas and are ideally selected to create current densities that are approximately equal in respective treatment areas.Type: GrantFiled: July 2, 2002Date of Patent: January 23, 2007Assignee: The Trustees of the University of PennsylvaniaInventors: Carl T Brighton, Solomon R Pollack
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Patent number: 7158835Abstract: A technique and device for preventing and/or treating osteoporosis, hip and spine fractures, and/or spine fusions by incorporating at least one conductive coil (110) into a garment (90) adapted to be worn adjacent to the patient's skin over a treatment area and applying an electrical signal to the coil effective to produce a magnetic flux the penetrates the treatment area so as to produce an electric field in the bones and the treatment area.Type: GrantFiled: July 10, 2002Date of Patent: January 2, 2007Assignee: The Trustees of the University of PennsylvaniaInventors: Carl T. Brighton, Solomon R. Pollack
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Publication number: 20040220621Abstract: A method and apparatus for delivering corrective therapy through hormone regulation is provided. Inhibition of sympathetic fibers by spinal cord stimulation is used to regulate the levels of hormones such as catecholamines, renin, and calcitonin gene-related peptide. The invention utilizes a closed or open loop feedback system in which physiological parameters such as the concentrations of hormones and sympathetic indicators such as heart rate and urine production are monitored and used to determine the appropriate level of neurostimulation.Type: ApplicationFiled: April 30, 2003Publication date: November 4, 2004Inventors: Xiaohong Zhou, Thomas J. Mullen, Gary W. King, Michael R.S. Hill
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Publication number: 20040172093Abstract: In one aspect the present disclosure provides a method of rehabilitating a person who has suffered spinal cord damage including the steps of providing exercise equipment capable of exercising a person's limbs, providing functional electrical stimulation to the person's limbs to be exercised in order to operate the exercise equipment, reducing the level of functional electrical stimulation as the person's muscles tire, decreasing a resistance provided by the exercise equipment or providing assistance to maintain an acceptable speed of the exercise equipment, and completely removing functional electrical stimulation to the person's limbs and providing assistance to maintain an acceptable speed of the exercise equipment. Also provided are apparatus to carry out the method.Type: ApplicationFiled: January 31, 2003Publication date: September 2, 2004Inventor: Patrick D. Rummerfield
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Publication number: 20040111118Abstract: A method of performing a medical procedure, such as surgery, is provided. The spinal cord is stimulated in order to control at least one physiological function. The medical procedure is performed and stimulation of the spinal cord is stopped.Type: ApplicationFiled: November 19, 2003Publication date: June 10, 2004Inventors: Michael R.S. Hill, Scott E. Jahns, James R. Keogh
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Publication number: 20040059394Abstract: A stimulator and a method for electrical stimulation of bone to promote osteogenesis is disclosed in which surface electrodes positioned around an incision site transmit an interferential current that has a base medium frequency alternating current between 1K-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate two circuits for use in producing the interferential current. The effective area of stimulation is controlled by placement of electrodes and electrode orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation.Type: ApplicationFiled: August 1, 2003Publication date: March 25, 2004Inventors: William J. Carroll, Michael B. McGraw, William A. Rux