Electrical Therapeutic Systems Patents (Class 607/2)
  • Patent number: 11911608
    Abstract: A subcutaneously implantable device includes a housing and an anchoring mechanism attached to the housing that is configured to anchor the device to a muscle, a bone, and/or a first tissue. The device further includes a first prong with a proximal end attached to the housing and a distal end extending away from the housing that is configured to be positioned adjacent to a first blood vessel, and a first electrode on the distal end of the first prong that is configured to be positioned adjacent to the first blood vessel. Circuitry in the housing is in electrical communication with the first electrode that is configured to deliver electrical stimulation using the electrode to create an electric field around the blood vessel.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: February 27, 2024
    Assignee: Manicka Institute LLC
    Inventor: Yatheendhar D. Manicka
  • Patent number: 11890465
    Abstract: Methods and systems for providing neuromodulation therapy are disclosed. The systems include an Implantable Pulse Generator (IPG) or External Trial Stimulator (ETS) that is capable of sensing an Evoked Compound Action Potential (ECAP), and (perhaps in conjunction with an external device) is capable of adjusting a stimulation program while based on the sensed ECAP. The stimulation program may include a pre-pulse component that may be adjusted based on the sensed ECAP. Moreover, stimulation may be applied to neural elements timed to coincide with the arrival of ECAPs at those neural elements. The stimulation may enhance or suppress activation of those neural elements.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: February 6, 2024
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Tianhe Zhang, Rosana Esteller, Natalie Brill
  • Patent number: 11895764
    Abstract: A dielectric barrier discharge tube includes a quartz tube, the middle of the quartz tube is sleeved with a high-voltage electrode, an inner electrode is arranged in the quartz tube, a drive fan is arranged at the end of the inner electrode, a discharging needle set is arranged on the surface of the inner electrode, and a spiral discharging wire is suspended and arranged at the tip of the discharging needle set. After a high voltage electric field is applied to the high voltage electrode, the discharging needle set and the spiral discharging wire discharge, the discharging needle set and the spiral discharging wire discharge at different time points. When the gas passes through the driving fan, the flow direction of the gas is changed. A cyclone can be generated to drive the gas to flow towards the discharging area.
    Type: Grant
    Filed: July 2, 2023
    Date of Patent: February 6, 2024
    Assignee: HANGZHOU CITY UNIVERSITY
    Inventors: Qi Qiu, Pengfei Wang, Qinmin Yang
  • Patent number: 11886472
    Abstract: Systems and methods are provided for improved interactive graphical user interfaces. The system allows users to visually construct queries of a database. The system can dynamically generate visual representations of supplemental data and cumulative data. Users can share annotations related to user input queries via the graphical user interface.
    Type: Grant
    Filed: September 1, 2022
    Date of Patent: January 30, 2024
    Assignee: Palantir Technologies Inc.
    Inventors: Michael Shelton, Radu-Andrei Szasz, Walker Burgin, Zhen Dai
  • Patent number: 11883648
    Abstract: The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: January 30, 2024
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventor: Dirk De Ridder
  • Patent number: 11883087
    Abstract: Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to methods including selectively neuromodulating afferent or efferent renal nerves. One or more measurable physiological parameters corresponding to systemic sympathetic overactivity or hyperactivity in the patient can thereby be reduced. Selectively neuromodulating afferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a renal pelvis. This can include, for example, neuromodulating via fluid within the renal pelvis. Selectively neuromodulating efferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a portion of a renal artery or a renal branch artery proximate a renal parenchyma. This can include, for example, neuromodulating via a therapeutic element within the portion of the renal artery or the renal branch artery.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: January 30, 2024
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Stefan Tunev, Julie Trudel
  • Patent number: 11883671
    Abstract: Systems, apparatus, and methods for treating medication refractory epilepsy are disclosed. In one embodiment, a method of treating epilepsy is disclosed comprising detecting, using a first electrode array coupled to a first endovascular carrier, an electrophysiological signal of a subject. The method further comprises analyzing the electrophysiological signal using a neuromodulation unit electrically coupled to the first electrode array and stimulating an intracorporeal target of the subject using a second electrode array coupled to a second endovascular carrier implanted within a part of a bodily vessel superior to a base of the skull of the subject.
    Type: Grant
    Filed: August 10, 2021
    Date of Patent: January 30, 2024
    Assignees: Synchron Australia Pty Limited, The University of Melbourne
    Inventors: Nicholas Lachlan Opie, Thomas James Oxley, Gil Simon Rind
  • Patent number: 11885816
    Abstract: The present invention includes methods for selecting a therapy for improved cognition as well as prevention of cognitive loss/dysfunction using one or more endophenotypes comprising: obtaining a sample from a subject; measuring biomarkers that differentiate between an inflammatory, a metabolic, a neurotrophic, and a depressive endophenotype; and selecting a course of treatment for the subject based on whether the subject is scored as having a high or a low endophenotype for one or more of the inflammatory, a metabolic, a neurotrophic, and a depressive endophenotypes.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: January 30, 2024
    Assignee: University of North Texas Health Science Center at Forth Worth
    Inventor: Sid E. O'Bryant
  • Patent number: 11878181
    Abstract: An erythrocyte de-aggregation system includes a band, including a strap and housing securing an iron-cored, micro-coil to an appendage, such as a wrist, of a subject to apply a PEMF into a target vessel in the vascular system of the subject. Typically, all of the blood circulates about the body within a matter of a few minutes, some within seconds, thus treating the entire bloodstream over time. The portable PEMF system intensifies both the concentration of electromagnetic flux per unit area, as well as the depth of penetration into the body. The portable PEMF systems relies on the body's circulatory system to eventually pass the body's entire volume of blood past it over a period of time.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: January 23, 2024
    Assignee: PULSE, LLC
    Inventors: Gregory S. Anderson, Kade E. Huntsman, Dale C. Gledhill, Marc E. Jackson
  • Patent number: 11877838
    Abstract: A method for preventing cytokine storm by suppressing clonal expansion of hyperactivated lymphocytes in a COVID-19 infected patient. The method includes placing at least four electrodes on skin of the COVID-19 infected patient by putting at least two electrodes at two locations over chest in front of ribcage of the COVID-19 infected patient and putting at least two other electrodes at two locations adjacent to lung tissue of the COVID-19 infected patient and suppressing mitosis of hyperactivated proliferative lymphocytes cells within the lung tissue of the COVID-19 infected patient by electrically stimulating the hyperactivated proliferative lymphocytes. Electrically stimulating the hyperactivated proliferative lymphocytes includes generating an alternating electric field (AEF) within the lung tissue by applying an AC voltage to the at least four electrodes and periodically changing a direction of the generated AEF in a plurality of directions within the lung tissue.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: January 23, 2024
    Assignee: NANO HESGARSAZAN SALAMAT ARYA
    Inventors: Mohammad Ali Khayamian, Mohammad Abdolahad, Hamed Abadijoo, Mahsa Faramarzpour Darzini, Mohammadreza Ghaderinia, Hossein Simaee, Seyed Mojtaba Yazdanparast, Shahriar Shalileh
  • Patent number: 11878173
    Abstract: Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: January 23, 2024
    Assignee: Duke University
    Inventors: Warren M. Grill, David T. Brocker
  • Patent number: 11864906
    Abstract: A method includes implanting an implantable biosensor within a subject where the implantable biosensor has an array of light sources and an array of light detectors, activating the array of light sources to direct light signals at a targeted tissue site in the subject, capturing, with the light detectors, the light signals reflected off the targeted site, calculating a roundtrip propagation time for each of the light signals and comparing the roundtrip propagation time for each of the light signals against previous calculated respective roundtrip propagation times to determine an occurrence of a change in the targeted tissue site.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: January 9, 2024
    Assignee: International Business Machines Corporation
    Inventors: Steven J. Holmes, Devendra K. Sadana, Stephen W. Bedell
  • Patent number: 11864773
    Abstract: Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: January 9, 2024
    Inventor: Steve Eugene Everett
  • Patent number: 11865344
    Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level. Between titration sessions one or more parameters, such as, for example, an acclimation interval, may be adjusted based on the patient's response to the stimulation. This personalized titration process can minimize the amount of time required to complete titration so as to begin delivery of the stimulation at therapeutically desirable levels.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: January 9, 2024
    Assignee: LivaNova USA, Inc.
    Inventors: Imad Libbus, Bruce H. KenKnight, Badri Amurthur, Scott R. Stubbs
  • Patent number: 11865329
    Abstract: Devices, systems and methods are disclosed for treating one or more symptoms of post-traumatic stress disorder (PTSD) in a patient. A method includes positioning a contact surface of a device in contact with an outer skin surface of patient and applying an electrical impulse transcutaneously from the device through the outer skin surface of the patient to a vagus nerve in the patient for about 90 seconds to about 3 minutes. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of PTSD are reduced. For chronic treatment of PTSD, a stimulation protocol is provided that includes two or more doses administered per day for a period of time sufficient to relieve the symptoms.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: January 9, 2024
    Assignee: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Patent number: 11857781
    Abstract: The inventive concept relates to a needle tip for application of current, a hand piece, and a skin treatment apparatus that are equipped with a needle in which an electromagnetically-energized active region is formed as a partial region other than a tip end of the needle is exposed in a non-insulated state.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: January 2, 2024
    Assignee: JEISYS MEDICAL INC.
    Inventors: Dong Hwan Kang, Hye Jin Sun
  • Patent number: 11850056
    Abstract: Systems and methods for remote therapy and patient monitoring are provided. A method comprises contacting an outer skin surface of a patient with a contact surface of a stimulator and transmitting an electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. Data related to parameters of the electrical impulse applied to the nerve is stored and transmitted to a remote source. The data may include duration of treatment, amplitude of the electrical impulse, compliance with a prescribed therapy regimen or other relevant data related to the therapy. The method may further include collecting patient status data, such as symptoms of a medical condition (e.g., severity of a headache) before, during and/or after stimulation. The patient status data is correlated with the treatment data to monitor compliance and/or the effectiveness of the therapy.
    Type: Grant
    Filed: July 27, 2022
    Date of Patent: December 26, 2023
    Assignee: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Patent number: 11844945
    Abstract: The present invention relates to methods for remotely tuning treatment parameters in movement disorder therapy systems where the subject and clinician are located remotely from each other. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: December 19, 2023
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 11839566
    Abstract: A sensor device for identifying an ostomy effluent leak location in an ostomy system includes a stoma opening and electrically conductive circuitry arranged in pattern around the stoma opening. The electrically conductive circuitry includes a first electrode and a second electrode spaced from the first electrode. The first electrode is subdivided by a plurality of resistors spaced along a length of the first electrode. The second electrode extends as a continuous strip of conductive material. The sensor device is configured to detect electrical resistance in the electrically conductive circuit and identify a location of a leak based on the detected electrical resistance.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: December 12, 2023
    Assignee: Hollister Incorporated
    Inventors: Jonas P. Carlsson, Scott E. Liddle, Kyle A. Matthews
  • Patent number: 11826567
    Abstract: An electrical treatment device (200) includes a treatment content setting unit (302), a treatment execution unit (306), and an output control unit (304) that outputs a pulse voltage at a first frequency within a predetermined frequency range before treatment of a site is performed by the treatment execution unit (306). When the pulse voltage is output at the first frequency, the treatment content setting unit (302) receives input of an electrical stimulation intensity desired by a user. The treatment execution unit (306) executes the treatment of the site by varying the pulse voltage corresponding to the electrical stimulation intensity desired by the user within the predetermined frequency range.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: November 28, 2023
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Mitsuru Samejima, Yui Watanabe, Shozo Takamatsu
  • Patent number: 11819333
    Abstract: A method includes implanting an implantable biosensor within a subject where the implantable biosensor has an array of light sources and an array of light detectors, activating the array of light sources to direct light signals at a targeted tissue site in the subject, capturing, with the light detectors, the light signals reflected off the targeted site, calculating a roundtrip propagation time for each of the light signals and comparing the roundtrip propagation time for each of the light signals against previous calculated respective roundtrip propagation times to determine an occurrence of a change in the targeted tissue site.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 21, 2023
    Assignee: International Business Machines Corporation
    Inventors: Steven J. Holmes, Devendra K. Sadana, Stephen W. Bedell
  • Patent number: 11813031
    Abstract: A system for delivering energy to a patient's body includes a plurality of probes, a touch-sensitive display screen, and a controller communicatively coupled to each of the probes and the display screen. The controller is configured to perform operations including displaying a plurality of dynamically sized channel control regions within a user interface of the touch-sensitive display screen. Each of the plurality of channel control regions corresponds with at least one of the plurality of probes and is sized based at least in part on a number of the plurality of probes. The operations can include detecting a user touch action directed to a user-selected channel control region of the plurality of dynamically sized channel control regions. The operations can include performing a control action associated with the probe(s) that correspond with the user-selected channel control region when the user touch action is detected.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: November 14, 2023
    Assignee: Avent, Inc.
    Inventors: Joseph A. Cesa, Lisa M. McGregor, Jennifer J. Barrett, Tyler W. Crone, Lee W. Rhein, Christopher W. Thurrott, Morgan Rudolph, Scott Woodruff
  • Patent number: 11813222
    Abstract: An apparatus includes a vibrational transducer, a placement band, a driver module and a control module. The placement band is configured to hold the vibrational transducer adjacent to the skin surface overlying the cricoid cartilage and trachea region of a patient's neck. The driver module is configured to apply a drive signal to the vibrational transducer. The control module is configured to receive at least one input configured to provide vibrational operating information and control the driver module to cause the vibrational transducer to apply a vibratory stimulation in an amount determined, at least in part, by the vibrational operating information.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: November 14, 2023
    Assignee: James Madison Innovations, Inc.
    Inventor: Christy Leslie Ludlow
  • Patent number: 11813472
    Abstract: In one example in accordance with the present disclosure, an emitter system is described. The emitter system includes an array of emitters. Each emitter emits waves towards a target surface. The emitter system also includes a control system. The control system includes a sensing system to determine whether emitters in the array are properly positioned relative to the target surface. A controller of the control system adjusts emitter sets of the array of emitters based on an output of the sensing system.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: November 14, 2023
    Assignee: NeuroEM Therapeutics, Inc.
    Inventors: Gary W. Arendash, Rob Baranowski
  • Patent number: 11813469
    Abstract: The disclosure relates to an implant comprising a housing, in which there are arranged an energy store and an electronics module, wherein a feedthrough to an electrode connection device is formed on the housing, wherein a first contact forms an electrical connection between the energy store and the electronics module, wherein a second contact forms an electrical connection between the electronics module and the feedthrough, and wherein the first contact and the second contact are oriented in the same contact direction. A method for assembling an implant is also disclosed.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: November 14, 2023
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Thomas Doerr, Ulrich Feese, Rolf Klenner, Torsten Oertmann
  • Patent number: 11794018
    Abstract: Techniques are disclosed for treating arrhythmias using an implantable medical device. An implantable medical device that is adapted for implantation wholly within a heart chamber of the heart of a patient may include a reservoir containing one or more therapeutically useful doses of a drug for treating an arrhythmia. The implantable medical device may include processing circuitry configured to detect an occurrence of the arrhythmia in the heart of the patient. The implantable medical device may include a valve operable to be opened in response to detecting the occurrence of the arrhythmia in the heart of the patient to release a therapeutically useful dose of the drug into the heart of the patient to treat arrhythmia of the heart.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: October 24, 2023
    Assignee: Medtronic, Inc.
    Inventor: Brad C. Tischendorf
  • Patent number: 11786742
    Abstract: An operating room cable assembly for electrically coupling at least one implantable electrical stimulation lead to a trial stimulator includes an elongated body; a trial stimulator connector disposed at one end of the elongated body; and a lead connector disposed at another end of the elongated body. The lead connector can include one or more buttons that can be pushed to load a lead into the lead connector and released to retain the lead. Alternatively, the lead connector can include a lever that can be operated to load the lead. A further alternative is a slider with a lead engagement element that can be slid between positions allowing loading of a lead and engagement of the lead. Other alternatives include a lead connector with doors that can swing open to allow loading of a lead or a collet/sleeve that can be tightened on the lead.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: October 17, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Joshua Dale Howard, Christopher Shanahan, Geoffrey Abellana Villarta, Peter J. Yoo
  • Patent number: 11779768
    Abstract: A method of modifying tissue behavior, comprising: determining a desired modification of tissue behavior for at least one of treatment of a disease, short or long term modification of tissue behavior, assessing tissue state and assessing tissue response to stimulation; selecting an electric field having an expected effect of modifying protein activity of at least one protein as an immediate response of a tissue to the field, said expected effect correlated with said desired modification; and applying said field to said tissue.
    Type: Grant
    Filed: November 11, 2021
    Date of Patent: October 10, 2023
    Assignee: Impulse Dynamics NV
    Inventors: Benny Rousso, Yuval Mika, Shlomo Ben-Haim, Hani N. Sabbah
  • Patent number: 11779392
    Abstract: Provided herein are methods, systems, and devices for increasing heat shock protein expression and treating conditions for which increased heat shock protein expression is expected to be beneficial using thermal ablation.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: October 10, 2023
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Ayala Hezi-Yamit, Susan Edwards, Carol Sullivan
  • Patent number: 11771912
    Abstract: Provided is a cancer treatment device which includes a first electrode and a second electrode, which are electrically connected to a signal generator and face each other with a target area therebetween, and a temperature sensor which is electrically connected to the signal generator and disposed adjacent to the target area. A cancer cell is present in the target area. The signal generator applies an AC voltage between the first electrode and the second electrode to generate an electric field between the first electrode and the second electrode. The signal generator changes an intensity of the electric field on the basis of a temperature detected from the temperature sensor. Each of the first electrode and the second electrode includes a ferroelectric material doped with manganese.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: October 3, 2023
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Dae-Sik Lee, Hyung Ju Park
  • Patent number: 11766562
    Abstract: Devices, systems and methods are disclosed for treating seizures, such as epileptic seizures, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A stimulator comprises a contact surface, such as an electrode, for contacting an outer skin surface of a patient. The stimulator is configured for coupling to a mobile device configured to receive a wireless signal. The stimulator is configured to transmit the electrical impulse through the contact surface and the outer skin surface sufficient to modulate a nerve within a patient and to ameliorate one or more symptoms of a seizure in the patient.
    Type: Grant
    Filed: December 4, 2021
    Date of Patent: September 26, 2023
    Assignee: ElectroCore, Inc.
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Patent number: 11759392
    Abstract: An auricular acupuncture patch to which an energy and blood stimulating part is attached is disclosed. The auricular acupuncture patch according to the present invention is attached along the reflect point of the ear, thereby being effective for treating dizziness, headaches, gastritis, asthma, gastroduodenal ulcers, enteritis, abdominal pain, diarrhea, bowel dysfunction, menstrual irregularity, insomnia, migraines, phobias, nervous vomiting, high fever, skin pruritus, oligogalactia, indigestion, obesity, smoking, and the like, and enabling the replacement of a decorative part, which are formed on the auricular acupuncture patch having the energy and blood stimulating part attached thereto, so as to provide various aesthetic effectiveness and conveniences in replacement.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: September 19, 2023
    Assignee: SEIGA INC.
    Inventor: Kyung Tho Lee
  • Patent number: 11764994
    Abstract: Embodiments of this present disclosure may include an industrial control system that uses a daisy chain communication network to couple point-to-point sensors (P2P sensors) for communication of data between respective P2P sensors and a controller. Each P2P sensor may couple to the daisy chain communication network via accessing circuitry. The accessing circuitry may include switching circuitry and flip-flop circuitry to control when each P2P sensors may communicate with the controller via the daisy chain communication network.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: September 19, 2023
    Assignee: ROCKWELL AUTOMATION TECHNOLOGIES, INC.
    Inventor: Alan J. Campbell
  • Patent number: 11752330
    Abstract: The invention relates to an electrode body (20) of an electrode assembly for electrically stimulating tissue of a living being, more particularly for neurostimulation. The electrode body (20) is designed to be arranged at a point between the skull and the scalp of a living being. The electrode body (20) has a stimulation surface, which is designed to be brought into contact with the tissue of the living being in order to produce an electrical stimulation of the tissue by alternating-current pulses and/or direct-current pulses.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: September 12, 2023
    Assignee: PRECISIS AG
    Inventors: Michael Tittelbach, Angela Liedler, Gregor Remmert, Lasse Jagschies, Thorsten Göttsche, Maik Gräfe
  • Patent number: 11745007
    Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: September 5, 2023
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Andrew B. Kibler, Marcelo Baru, Dirk Muessig
  • Patent number: 11730952
    Abstract: A hippocampal prosthesis for bypassing a damaged portion of a subject's hippocampus and restoring the subject's ability to form long-term memories. The hippocampal prosthesis includes a first set of hippocampal electrodes configured to receive an input signal from at least one of the subject's hippocampus or surrounding cortical region. The hippocampal prosthesis includes a processing device having a memory and one or more processors operatively coupled to the memory and to the first set of hippocampal electrodes. The processing device being configured to generate an output signal based on the input signal received from the first set of hippocampal electrodes. The hippocampal prosthesis includes a second set of hippocampal electrodes operatively coupled to the one or more processors and configured to receive and transmit the output signal to the subject's hippocampus.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: August 22, 2023
    Assignee: University of Southern California
    Inventors: Dong Song, Theodore William Berger
  • Patent number: 11730963
    Abstract: Methods and apparatuses for setting a therapeutic dose of a neuromodulator implanted into a patient. The therapeutic dose typically includes a therapeutic dose duration including a ramp-up time to reach a peak modulation voltage and a sustained peak modulation time during which the voltage is sustained at the peak modulation voltage. The methods and apparatuses may use a testing ramp to identify a peak modulation voltage that is patient-specific and provides a maximized therapeutic effect while remaining comfortably tolerable by the patient during the application of energy by the neuromodulator.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: August 22, 2023
    Assignee: Neuros Medical, Inc.
    Inventors: Nemath Syed Shah, Zi-Ping Fang
  • Patent number: 11724104
    Abstract: The present invention provides an advancement in the art of cardiac pacemakers. The invention provides a novel and unobvious pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a novel design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: August 15, 2023
    Assignees: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Raymond Peck, Steven Nutt
  • Patent number: 11723709
    Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: August 15, 2023
    Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Govindarajan Srimathveeravalli, Stephen Barnett Solomon
  • Patent number: 11724101
    Abstract: An apparatus, system and method are provided for a wireless electrical stimulation. The apparatus generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The apparatus also includes a receiver configured for receiving the one or more control signals from a remote controller for remotely, wirelessly controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes. The apparatus generally applies to a foot of a human body.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: August 15, 2023
    Assignee: HI-DOW IPHC, INC.
    Inventor: Eric Chen
  • Patent number: 11728018
    Abstract: There are provided herein a system and a computer implemented method for preventing, mitigating or treating partial/complete loss of effect of one or more drugs or medical devices administered to or used by a subject in need thereof due to adaptation, tolerance, and/or tachyphylaxis, and/or for preventing, mitigating or treating non-responsiveness to one or more drugs, maximizing therapeutic effect of one or more drugs, or for improving target or non-target organ/organs response to therapy, the system/method include (processing circuit configured to): receiving a plurality of physiological or pathological parameters of the subject; applying a machine learning algorithm on the plurality of physiological or pathological parameters; and determining a subject-specific administration regimen of a drug or a medical treatment, wherein the administration regimen comprises drug administration parameters, cell/tissue/organ stimulation parameters, adjuvant parameters or any combination thereof; wherein the administratio
    Type: Grant
    Filed: July 1, 2018
    Date of Patent: August 15, 2023
    Assignee: OBERON SCIENCES ILAN LTD
    Inventors: Yaron Ilan, Tahel Ilan Ber
  • Patent number: 11717343
    Abstract: Systems and methods for neuromodulation therapy are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, intravascularly positioning a plurality of ablation electrodes within a blood vessel lumen at a treatment site. The method can include analyzing a renal neuromodulation target site of a patient to obtain patient-specific data related to the renal neuromodulation target site, and based on the patient specific data, delivering neuromodulation treatment to the patient via one or more of the ablation electrodes.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: August 8, 2023
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Paul J. Coates, Robert J. Melder
  • Patent number: 11712715
    Abstract: Aspects of the application provide methods of producing substrates having modified surfaces. In some aspects, methods of surface modification involve treating a surface of a substrate with an organic reagent in vapor phase to form an organic layer over the surface. In some aspects, methods of forming a stable surface coating on an oxidized surface are provided.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 1, 2023
    Assignee: Quantum-Si Incorporated
    Inventors: Guojun Chen, Jeremy Lackey
  • Patent number: 11710320
    Abstract: A system for monitoring a patient in a patient area having one or more detection zones, the system comprising one or more cameras, a user interface, and a computing system configured to receive a chronological series of frames from the one or more cameras, identify liquid candidates by comparing a current frame with a plurality of previous frames of the chronological series, determine locations of the liquid candidates, identify thermal signatures of the liquid candidates, determine types of liquids of the liquid candidates based on the locations and thermal signatures of the liquid candidates, and generate an alert with the user interface corresponding to the determined types of liquids.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: July 25, 2023
    Assignee: CareView Communications, Inc.
    Inventors: Steven Gail Johnson, Derek del Carpio, Kenneth W. Chapman
  • Patent number: 11707220
    Abstract: Systems and methods for assessing sympathetic nervous system (SNS) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. The detector can measure cardiac data and the receiver and/or a device communicatively coupled thereto can analyze the cardiac data to provide one or more SNS tone indicators. The SNS tone indicators can be used to determine whether a patient will be responsive to a neuromodulation therapy and/or whether a neuromodulation therapy was effective.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: July 25, 2023
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Douglas Hettrick, Shantanu Sarkar
  • Patent number: 11700772
    Abstract: Provided is a piezoelectric structure including a braid composed of a conductive fiber and piezoelectric fibers, the braid being a covered fiber having the conductive fiber as the core and the piezoelectric fibers covering the periphery of the conductive fiber, wherein the covered fiber has at least one bent section, and when the piezoelectric structure is placed on a horizontal surface, the height from the horizontal surface to the uppermost section of the piezoelectric structure is greater than the diameter of the covered fiber.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: July 11, 2023
    Assignees: TEIJIN FRONTIER CO., LTD., KANSAI UNIVERSITY
    Inventors: Yoshiro Tajitsu, Yuhei Ono, Shunsuke Kanematsu, Tomoyoshi Yamamoto
  • Patent number: 11691009
    Abstract: An apparatus includes a frame, a sensor, and an electric stimulator. The frame is removably couplable to a portion of a limb. The sensor is configured to produce a first signal associated with a gait characteristic at a first time, and a second signal associated with the gait characteristic at a second time, after the first time. The electric stimulator is removably coupled to the frame and is in electrical communication with an electrode assembly and the sensor to receive the first signal substantially at the first time and the second signal substantially at the second time. Based in part on the gait characteristic at the first time, the electric stimulator sends a third signal to the electrode assembly to provide an electric stimulation to a portion of a neuromuscular system of the limb substantially during a time period defined between the first time and the second time.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: July 4, 2023
    Assignee: Bioness Inc.
    Inventors: Arkady Glukhovsky, Keith McBride
  • Patent number: 11684779
    Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: June 27, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Changfang Zhu
  • Patent number: 11684796
    Abstract: A method for using a sonic wave to influence material in a target structure requires using a confined plasma antenna to generate an electromagnetic carrier wave, ?. The confined plasma antenna also pulses the carrier wave at a sonic frequency, f, to create a sonic wave. In detail, pulsing the carrier wave results in a sequential plurality of solitons which are separated from each other by a periodicity p, wherein ?«p. For the present invention, f is selected to resonate with a material (e.g. a cellular structure) in a target structure (e.g. a patient).
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: June 27, 2023
    Assignee: Crown Holdings, LLC
    Inventors: Robert Edward Grant, Matthew T. Case
  • Patent number: 11679252
    Abstract: Methods and devices are provided for activating brown adipose tissue (BAT) using electrical energy. In general, the methods and devices can facilitate activation of BAT to increase thermogenesis. The BAT can be activated by applying an electrical signal thereto that can be configured to target sympathetic nerves that can directly innervate the BAT. The electrical signal can be configured to target the sympathetic nerves using fiber diameter selectivity. In other words, the electrical signal can be configured to activate nerve fibers having a first diameter without activating nerve fibers having diameters different than the first diameter. Sympathetic nerves include postganglionic unmyelinated, small diameter fibers, while parasympathetic nerves that can directly innervate BAT include preganglionic myelinated, larger diameter fibers.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: June 20, 2023
    Assignee: Cilag GmbH International
    Inventors: Jason L. Harris, Tamara C. Baynham