Abstract: An apparatus for proliferation of organic tissue by exposure to electromagnetic field is disclosed that comprises an electromagnetic patch 101 comprising one or a plurality of electromagnetic coils 103 each generating an electromagnetic field; and a battery powered drive unit 102 which supplies signals to the electromagnetic coils for applying a particular dosage of electromagnetic field to a target tissue region. The electromagnetic patch 101 is specifically customised to an individual subject user and to an individual body portion and tissue region of said individual user. The drive signal sequence is individually tailored to the electromagnetic patch for delivering a particular dosage programme of electromagnetic field for the particular subject user.

Abstract: Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

Abstract: Systems, methods, and devices are provided for determining an early battery depletion (EBD) condition of an implantable medical device that includes a memory storing program instructions and a processor executing the program instructions. Circuitry is electrically coupled to the processor, and the circuitry and processor perform one or more tasks related to at least one of collecting signals indictive of physiologic activity, analyzing collected signals, delivering therapy, or communicating with an external device. A battery supplies energy to the circuitry and processor. A monitoring circuit coupled to the battery measures actual energy usage from the battery representing at least one of a current draw from the battery during corresponding tasks or a voltage measurement across the battery. Circuitry and processor calculate projected energy usage from the battery in connection with the corresponding tasks, and determine when an EBD condition exists based on projected energy usage and actual energy usage.

Abstract: An implantable neuro-modulator device, including a hermetically sealed housing, wherein an antenna for communicating with external devices and/or for wirelessly receiving electrical energy is positioned within the housing, wherein a major part of the housing is electromagnetically transparent to radiation in the frequency range below 20 MHz, in particular between 5 and 15 MHz.

Abstract: A lateral retractor system for forming a pathway to a patient's intervertebral disc space includes a single dilator and a retractable dual-tapered-blade assembly. The dilator may feature a narrow rectangular body for insertion at an insertion orientation parallel to the fibers of the patient's psoas muscle, at an approximate 45-degree angle to the patient's spine. The retractable dual-tapered-blade assembly consists of only two blade subassemblies, each having a blade bordered by adjustable wings, along with built-in lighting and video capabilities. The dual-tapered-blade assembly may be passed over the single dilator at the insertion orientation and rotated approximately 45-50 degrees to a final rotated orientation parallel to the intervertebral disc space before the two blade subassemblies are retracted away from one another to create the surgical pathway, while simultaneously and continuously assessing for encroachment upon one or more nerve structures within 360-degrees of the instrument.

Abstract: Disclosed is a neurofeedback device, including a body attached to a user's body and configured to provide electrical stimulation to a vagus nerve region, wherein the body includes: a frame provided in a symmetrical and elliptical shape, wherein one side and another side in a longitudinal direction are concavely recessed toward a center, and attached to a user's neck; a vagus nerve stimulator located on a back surface of the frame, provided to include a plurality of electrodes for providing electrical stimulation to the vagus nerve region, and attached to skin directly above the vagus nerve region located next to carotid artery of the user; a heart rate sensor located at a center of left and right symmetry of the frame on a back surface of the frame and configured to detect heart rates of the user; a manipulator located in front of the frame and configured to receive a user's command; and a plurality of connection ports formed on a side surface of the frame to transmit and receive signals, wherein the plural e

Abstract: AED patient protection circuitry is improved by using triode for alternating current (TRIACs), which are significantly smaller and cheaper than relays. The TRIACs are positioned between a defibrillation waveform generator and the pads through which defibrillation waveforms are delivered to the patient and alternate under the control of a processing element such as a microcontroller between a conductive state in which they allow the defibrillation waveforms to reach the patient through the pads and an isolated state in which they prevent the defibrillation waveforms from reaching the patient through the pads. A voltage monitor interfaced to the microcontroller can monitor current leakage from the TRIACs or other portions of the defibrillator, thus detecting degradation of patient protection circuitry and further increasing defibrillator safety and reliability.

Abstract: An adult toy includes a substantially hollow cylindrical body and a vagina-shaped element arranged inside the substantially hollow cylindrical body. The vagina-shaped element includes an opening at a first end of the substantially hollow cylindrical body to receive a male genital organ therein. The adult toy includes a chamber arranged between the substantially hollow cylindrical body and the vagina-shaped element, with the chamber surrounding the vagina-shaped element, and further includes an air pump arranged towards a second end of the substantially hollow cylindrical body. The air pump is disposed in fluid communication with an ambient atmosphere and the chamber and provides an air pressure inside the chamber. The chamber inflates and deflates based on the air pressure therein to cause the vagina-shaped element to compress and decompress to stimulate the male genital organ received therein.

Abstract: A method includes receiving, with one or more processors, a first ambulatory velocity information of a patient while electrical stimulation with a first set of stimulation parameters is being delivered to the patient; adjusting, based on the first ambulatory velocity information and by a predetermined amount, one or more of the first set of stimulation parameters to generate an adjusted set of stimulation parameters by a predetermined amount; receiving, with the one or more processors, a subsequent ambulatory velocity information of the patient while the electrical stimulation with an adjusted set of stimulation parameters is being delivered to the patient; and generating, with the one or more processors and based on the subsequent ambulatory velocity, one or more recommended electrical stimulation parameters the patient.

Abstract: This disclosure relates to a device for applying a neural stimulus. A battery supplies electrical energy at a battery voltage and an electrode applies the electrical energy to neural tissue. A circuit measures the nervous response of the tissue and a voltage converter receives the electrical energy from the battery and controls a voltage applied to the electrode based on the measured nervous response of the tissue. This direct voltage control is energy efficient because losses across a typical current mirror are avoided. Further, the control based on the measured nervous response leads to automatic compensation of impedance variation due to in-growth or change in posture. As a result, the stimulation results in a desired neural response.

Abstract: The disease management system can determine a measurement of one or more physiological parameters and can determine a disease event based on the one or more measurements. Furthermore, the disease management system can determine a pose of an individual using a pose sensor. Based on an identification of a disease event and a determination that the pose of the individual corresponds to a first pose, the disease management system can cause at least one of an audible, visual, or vibratory alarm. Based on an identification of a disease event and a determination that the pose of the individual does not correspond to the first pose, the disease management system can cause administration of a medication to the individual.

Abstract: The motion sickness estimation device includes an opening and closing detection unit configured to detect an opening/closing state of an eye of a vehicle occupant, a face direction estimation unit configured to estimate an orientation of a face of the occupant, and an occupant state estimation unit configured to calculate a traveling speed of the motion sickness with respect to the occupant based on the opening/closing state of the eye and the orientation of the face.

Abstract: This disclosure relates to implantable neuro stimulation devices with a feedback loop to control an amount of energy delivered into a neural tissue based on a measured evoked neural response. Stimulation electrodes deliver stimulation energy to neural tissue and a stimulator comprises a microprocessor and program memory with program code, which causes the microprocessor to perform closed-loop control of the stimulation energy based on a feedback signal that is indicative of an evoked neural response. A charge monitor monitors the delivery of energy to the stimulation electrodes by determining an amount of charge delivered by the stimulation electrodes and connected to the stimulator to provide a status signal indicative of the charge delivered to the stimulator. The device adjusts the control of the stimulation energy in response to the status signal from the charge monitor indicating undesirable charge delivery to the stimulation electrodes.

Abstract: In various embodiments methods and devices are provided for facilitating locomotor function and/or voiding of bladder and/or bowel in a subject with a neuromotor disorder. In certain embodiments the methods involve providing magnetic stimulation of the spinal cord at a location, frequency and intensity sufficient to facilitate locomotor function and/or voiding of bladder and/or bowel.

Abstract: Digital-to-Analog Converter (DAC) circuitry useable in a stimulator device is disclosed. The DAC circuitry produces an output current whose magnitude varies as a function of an amplitude value provided by a digital amplitude bus. The relationship of the output current to the amplitude (Iout(A)) may be linear or non-linear depending on the current-voltage characteristics of a circuit in the DAC that is selected for use. For example, if a resistor is selected, the output current will vary linearly with amplitude; if a p-n diode is selected, the output current will vary exponentially with amplitude. The shape of Iout(A) affects the resolution of the output current, and depending on the circuit selected, can cause the resolution to be constant, or at least more constant, over the dynamic range of the DAC circuitry. The DAC circuitry is further beneficial in its ability to be programmed with a minimum and maximum output current.

Abstract: An upper extremity wearable device includes a pressure sleeve configure to wrap a forearm, a middle finger stimulating electrode and a ring finger stimulating electrode disposed on an inner surface of the pressure sleeve. The middle finger stimulating electrode covers a middle finger stimulating point which is measured from an ulnar styloid process, moving two lateral units, and moving four longitudinal units. The ring finger stimulating electrode covers a ring finger stimulating point which is measured from the ulnar styloid process, moving one lateral unit, and moving five longitudinal units. The lateral unit is a distance from the position of the pressure sleeve corresponding to the ulnar styloid process to a radial styloid process dividing four. The longitudinal unit is a distance from the position of the pressure sleeve corresponding to the ulnar styloid process to an olecranon process dividing twelve.

Abstract: The present invention relates to a radio frequency energy harvester module and an optimization circuit for efficient power conversion and storage. The harvester module receives an AC input voltage from a wireless power source, rectifies it into a DC voltage, and uses a piezoelectric transformer to convert this voltage into a transformed AC signal, which is subsequently rectified to generate a stable DC output. The system includes a DC to AC converter or an oscillator to generate excitation or oscillation signals, matched to the resonance frequency of the piezoelectric transformer. The invention also introduces an optimization circuit for managing power storage and delivery to external devices, ensuring adaptive and efficient energy usage. The method includes steps for converting wireless power into usable DC output using rectification, piezoelectric transformation, and feedback-based optimization.

Abstract: A method of controlling operation of a neurostimulation device comprises receiving, by the neurostimulation device, an indication of a physiological search area of a subject for delivering electrical neurostimulation and a prioritized search list of neurostimulation parameters for neurostimulation therapy delivered to the search area; delivering the neurostimulation therapy to the search area and varying the neurostimulation parameters according to the parameter priority, wherein a highest priority parameter is varied first while lower priority parameters are held constant; determining the optimum value of the highest priority parameter; delivering neurostimulation to the search area using the determined optimum value of the highest priority parameter and varying one or more lower priority parameters according to the parameter priority; and determining optimum lower priority parameters for the neurostimulation.

Abstract: A system for electrical stimulation may comprise a plurality of electrodes and a processor. The processor may be configured to: define a region of interest (ROI) for electrode activation via a first subset of the plurality of electrodes; and define a second subset of electrodes, wherein each electrode within the second subset of electrodes are positioned away from the ROI such that the average distance between each electrode and the ROI is maximized. The second group of electrodes may be defined via low-discrepancy sequences or an equidistributed sequence. The plurality of electrodes may be part of a wearable garment or an implantable device. The system may be for muscle stimulation or neural simulation.

Abstract: An electrical stimulation method is provided in the present disclosure. The electrical stimulation method is applied to an electrical stimulation device. The electrical stimulation method includes the steps of using the electrical stimulation device to obtain an electrical stimulation level, wherein the electrical stimulation level corresponds to the target energy; and using the electrical stimulation device to perform the electrical stimulation on the target area of a target object according to the target energy, wherein during the electrical stimulation, all electrodes of the electrical stimulation device are activated.

Abstract: Methods, systems, and devices are described for mapping and treating tissue during a medical procedure. In some cases, a device includes a mesh of wires with sensors coupled thereto. The mapping device can be coupled to an expandable treatment element. Alternatively, the treatment device can be a separate device, and advanced through an access lumen in the mapping device. The expandable treatment element can include multiple segments. The sensors can be used to map a tissue area and monitor the tissue during a medical procedure.

Abstract: The method of optimizing an intracranial implantation scheme of a set of electroencephalographic electrodes for identification of an epileptogenic zone in an epileptic patient's brain includes: —providing a model of the epileptogenic zone and a model of the propagation of an epileptic discharge from the epileptic zone to a propagation zone, and loading the models in a computerized platform personalized according to the patient's brain; —providing at least one hypothesis of the localization of the epileptogenic zone in the patient brain; —for the at least hypothesis of the localization of the epileptogenic zone, simulating, in the personalized computerized patient's brain, epileptic seizures, and determining, for the hypothesis and epileptic seizures, a network of propagation zones; —for a plurality of intracranial implantation schemes of the electroencephalographic electrodes, obtaining, using the personalized computerized patient's brain, simulated electroencephalographic signals activity to be measured by t

Abstract: A percutaneous catheter system for use within the human body and an ablation catheter for ablating a selected tissue region within the body of a subject. The percutaneous catheter system can include two catheters that are operatively coupled to one another by magnetic coupling through a tissue structure. The ablation catheter can include electrodes positioned within a central portion. The ablation catheter is positioned such that the central portion of a flexible shaft at least partially surrounds the selected tissue region. Each electrode of the ablation catheter can be activated independently to apply ablative energy to the selected tissue region. The ablation catheter can employ high impedance structures to change the current density at specific points. Methods of puncturing through a tissue structure using the percutaneous catheter system are disclosed. Also disclosed are methods for ablating a selected tissue region using the ablation catheter.

Abstract: A medical system for performing a therapeutic function on a patient comprises an implantable medical device having a switching function to switch from a normal operating mode to an MRI compatible operating mode in the presence of an MRI device, and an external device for programming at least one setting of the implantable medical device. The external device is configured, based on a programming event relating to said at least one setting, to generate a notification prompting a user to confirm a continuing MRI compatibility of said MRI compatible operating mode after the programming event and/or to amend said at least one setting for achieving MRI compatibility.

Abstract: An example system includes a first lead configured to be positioned in or beside a left internal jugular vein (IJV) of a patient to deliver a first stimulation signal to a first vagus nerve, the first lead including one or more first segmented electrodes positioned on a distal portion of the first lead and a first anchoring mechanism; a second lead configured to be positioned in or beside a right IJV of the patient to deliver a second stimulation signal to a second vagus nerve, the second lead including one or more second segmented electrodes positioned on a distal portion of the second lead and a second anchoring mechanism; and circuitry configured to deliver electrical energy to the first lead to deliver the first stimulation signal and the second lead to deliver the second stimulation signal to provide bilateral stimulation to the first vagus nerve and the second vagus nerve.

Abstract: A subcutaneously implantable device includes a housing and an anchoring mechanism attached to the housing that is configured to anchor the device to a muscle, a bone, and/or a first tissue. The device further includes a first prong with a proximal end attached to the housing and a distal end extending away from the housing that is configured to be positioned adjacent to a first blood vessel, and a first electrode on the distal end of the first prong that is configured to be positioned adjacent to the first blood vessel. Circuitry in the housing is in electrical communication with the first electrode that is configured to deliver electrical stimulation using the electrode to create an electric field around the blood vessel.

Abstract: A pulse phase ablation biphasic PFA generator with finite energy source and delivery mechanism is disclosed, comprising: a signal source configured to output electrode input signals; a trigger circuit configured to trigger signals; at least one electrode channel circuit including a charge transfer source circuit including a source capacitor and coupled to the signal source to receive the electrode input signals, the charge transfer source circuit being configured to charge the source capacitor to a source voltage, a switching circuit coupled to charge transfer source circuit to receive the source voltage and to the trigger circuit to receive the trigger signals, and a charge transfer load circuit including a load capacitor coupled to the switching circuit; wherein the switching circuit further includes a plurality of spark gap switches activated by the trigger signals to cause the electrode channel to apply a biphasic waveform to electrodes configured to contact tissue.

Abstract: Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subjects hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.

Abstract: The present invention relates to an electrical stimulation system and a method thereof. The electrical stimulation system includes an electrical stimulation generator and at least one electrode structure. The electrical stimulation generator is used to generate an electric pulse combination which is transmitted to the skin of an individual through the electrode structure for stabilizing blood glucose fluctuations and reducing inflammation.

Abstract: Methods are presented for treating a subject having a disease or disorder comprising stimulating a vagus nerve of the subject with a corrective stimulus pattern derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific vagus neurogram in an amount and manner effective to treat the disease or disorder in a subject.

Abstract: A deployment tab for deploying a neural interface device, the deployment tab comprising a first portion configured, in use, to be positioned proximal to the neural interface device; and a connector, for releasably coupling the first portion to the neural interface device, the connector being anchored to the first portion.

Abstract: Systems and methods are provided for treating blood clots associated with a replicating pathogen, such as a virus in the coronaviridae family. The methods include emitting an electrical impulse near a vagus nerve within the patient sufficient to inhibit or reduce an inflammatory or allergic response in the patient, provide relief for bronchoconstriction that results in the tightening of airways and the inability to breath without ventilator support and/or lessen the abnormal blot clotting that develops in some patients. The systems and methods are particularly useful for treating post-COVID conditions or post-acute sequelae of COVID-19 that develop in “long-haul” or COVID patients.

Abstract: A medical lead includes a lead body, a connector pin proximate to a proximal end of the lead body, a helix extending from a distal end of the lead body, an electrode proximate to the distal end of the lead body, and a cable conductor within the lead body and including an electrode proximate a distal end of the cable conductor, the cable conductor being slideable within the lead body to extend and retract the electrode relative to the distal end of the lead body.

Abstract: A peripheral nerve stimulator to stimulate a peripheral nerve to treat essential tremor and other movement disorders, as well as overactive bladder, cardiac dysfunction and neurotransmitter dysfunction is provided. The peripheral nerve stimulator can be a noninvasive surface stimulator to provide multi-modal optimized therapy. Stimulation can be vibrational, electromechanical, thermal, radiant, electrical, magnetic, electromagnetic, light, mechanical, chemical, thermal, ultrasonic, radiofrequency (RF), acoustic, infrared, ultraviolet, x-ray, and/or microwave. Stimulation can be delivered using an open loop system and/or a closed loop system with feedback. Stimulation can be to one site or multiple sites.

Abstract: A transducer array including a conductive layer and a conductive gel layer is described. The conductive layer has one or more electrode element. The one or more electrode element is configured to receive electrical signals from an electric field generator producing an electric signal as a Tumor Treating Field. The conductive gel layer overlaps the one or more electrode element of the conductive layer. The conductive gel layer has a first region and a second region. The first region has a first resistivity and the second region having a second resistivity with the first resistivity being different from the second resistivity.

Abstract: Systems and methods are provided for influential control over a driver's hand(s) that grip a vehicle's steering wheel. Upon issuing an autonomous control signal to control motive operation of the vehicle, an autonomous control system of the vehicle may further reinforce the application of the autonomous control signal by inducing the driver's hand(s) to grip/increase grip strength on the vehicle's steering wheel or by releasing the grip/decreasing grip strength on the vehicle's steering wheel. Moreover, the increasing/decreasing of the driver's grip may alternatively, or in addition to the reinforcement aspect, induce augmentative or intervening action(s)/behavior(s) by the driver.

Abstract: An implantable medical device includes sealingly contained circuitry comprising stimulation circuitry, a sealingly contained power element to supply power to the circuitry, and an electrode array including a first electrode.

Abstract: A system for monitoring and responding to medical emergencies in high-humidity environments includes a processor, a memory storing computer-executable instructions, and a sensor array comprising motion detection, fall detection, and vital signs monitoring. The sensor array includes a steam-adaptive calibration configured to adjust detection thresholds based on vapor density and humidity levels. A privacy-preserving architecture processes non-identifiable inputs such as motion signatures, radar signals, or acoustic triggers without storing visual or audio recordings. When inactivity, collapse, or absence of respiration is detected for a predefined threshold period, the privacy-preserving architecture initiates a first notification to staff interface and response tools. If the first notification is not acknowledged within a predetermined escalation period, a secondary notification is transmitted. The system operates in real time to provide emergency alerts while preserving occupant privacy.

Abstract: Tracking a pose of a portion of an anatomical structure using an electromagnetic navigation system may comprise generating a signal. The generated signal is configured to cause bi-directional micro coils of a bi-directional coil array to generate an electromagnetic field at each bi-directional micro coil in response to receiving the generated signal. Each of the bi-directional micro coils is also coupled to a portion of a tracked structure. At least one of the generated electromagnetic fields is configured to be detected by at least one neighboring bi-directional micro coil and at least one receiving coil of a receiving coil array. A pose of a particular bi-directional micro coil of the bi-directional micro coils associated with the at least one generated magnetic field is determined based on detecting the at least one generated magnetic field at the at least one neighboring bi-directional micro coil and the at least one receiving coil.

Abstract: A device (103) for applying an electrical stimulation to one or more muscles of the mouth of the user, the device (103) includes one or more electrodes (132, 133) for applying electrical stimulation to one or more muscles of the mouth of a user and a sensor (140a, 140b, 141a, 141b) for determining the muscle tone of the tongue of the user. Also disclosed are methods and systems for determining a stimulation plan.

Abstract: In one aspect, a portable medical treatment and guidance apparatus for assisting a caregiver in evaluating and treating a patient experiencing a medical emergency according to a time sensitive prioritization of the medical emergency is provided. The portable medical treatment and guidance apparatus includes a housing having at least one compartment; a plurality of medical supplies housed within the at least one compartment; a user interface configured to receive input and provide an interactive query flow for assisting the user in providing medical treatment; and at least one processor and memory communicatively coupled to the user interface. The at least one processor and memory is configured to determine instructions for assisting the caregiver in treating the patient and present, via a user interface, the determined instructions to assist the caregiver in treating the medical emergency.

Abstract: A method of treating a patient with a bioelectrical system is provided. The method may include inserting a probe into a first position in an anatomy of the patient, the system being provided with a plurality of electrodes; energizing a first electrode of the plurality of electrodes with a measurement level of power; determining a complex impedance in the patient's anatomy; determining whether the first position is a desired position of the probe for ablating a predetermined portion of tissue of the patient, based on the complex impedance determined; and energizing one of the plurality of electrodes with an ablation level of power, the ablation level of power being greater than the measurement level of power. An apparatus for performing BIA on a patient is also provided.

Abstract: A brain machine interface (BMI) to control a device is provided. The BMI has a neural decoder, which is a neural to kinematic mapping function with neural signals as input to the neural decoder and kinematics to control the device as output of the neural decoder. The neural decoder is based on a continuous-time multiplicative recurrent neural network, which has been trained as a neural to kinematic mapping function. An advantage of the invention is the robustness of the decoder to perturbations in the neural data; its performance degrades less—or not at all in some circumstances—in comparison to the current state decoders. These perturbations make the current use of BMI in a clinical setting extremely challenging. This invention helps to ameliorate this problem. The robustness of the neural decoder does not come at the cost of some performance, in fact an improvement in performance is observed.

Abstract: Esophageal intubation assemblies, esophageal cardiac stimulation and gastric decompression assemblies, and methods for using and making the same are provided.

Abstract: An implantable medical device (IMD) includes multiple stimulation engines (SEs) for independently stimulating respective electrode sets of a lead system. A voltage multiplier (VM) is configured to generate an adjustable target voltage at an output node. Each stimulation engine includes first switching circuitry to switchably connect an anodic node of the SE to the VM output node and second switching circuitry to switchably connect a cathodic node of the SE to a current sink circuit. Discharge switching circuitry may be disposed between the anodic and cathodic nodes of each SE. A selector and associated digital control logic block are operative to generate control signals for independently controlling respective SEs such that each SE may be activated to stimulate or discharge a corresponding select set of electrodes independently from or in concert with remaining SEs.

Abstract: A method comprises establishing communication between a therapy device implantable in a patient and a consumer electronic device operable by the patient. The method comprises controlling, by the consumer electronic device, a predetermined set of therapy device functions in response to patient inputs to the consumer electronic device. The method also comprises transmitting therapy data from the therapy device to the consumer electronic device. The method further comprises presenting therapy data on a display of the consumer electronic device.

Abstract: A wearable cardioverter defibrillator (WCD) system is adapted for use by an ambulatory patient who already has an implanted pacemaker. If implanted, such a pacemaker may occasionally be emitting, without the knowledge of the WCD system, pacing signals that may be adding pacing artifacts to the ECG signal. The WCD system may use multiple electrodes to sense ECG signals along multiple vectors that have channels. In embodiments, the WCD system identifies a preferred one of its available channels according to how easily the pacing artifacts are detected within its ECG signal. When the patient's parameters indicate that an alert criterion is met, the WCD system may attempt to read the ECG signal from the preferred channel first. This way the WCD system may be able to identify faster the pacing artifacts, and therefore analyze the ECG signal faster, with an opportunity to react faster to the alert criterion being met.

Abstract: Disclosed herein are devices, systems, and methods for monitoring a formation of an iceball at a cryoablation needle. An example method includes receiving an impedance from at least one electrode in an electrode arrangement that is disposed at a cryoablation needle distal portion. The electrode arrangement is configured to engage the iceball as the iceball is formed over the cryoablation needle distal portion so as to cause a change in the impedance. The example method includes determining one or more physical attributes of the iceball based on a rate of the change in the impedance.

Abstract: A method for quantitatively assessing muscle contraction of a facial muscle in a person and determining the ability of a treatment material to reduce contraction of the facial muscle is disclosed. The method can include applying an external electrical stimulus to facial skin sufficient to contract a facial muscle, measuring the contractile activity of the contracted facial muscle by measuring the compound motor action potential (CMAP) of the contracted facial muscle to obtain a first average measurement of contractile activity of the contracted facial muscle, administering the treatment material by topically applying the treatment material to the facial skin, and repeating steps (a) and (b) to obtain a second average measurement of contractile activity of the contracted facial muscle.

Abstract: Described herein are high-power pulsed electromagnetic field (PEMF) applicator systems. The systems can comprise a base housing including a controller configured to generate a low-power control signal and one or more applicators coupled to the base. Each applicator can include a drive circuitry comprising a generator configured to receive the low-power control signal and to produce, in the applicator, a high-power pulsed electromagnetic field signal based on the low-power control signal. The high-power pulsed electromagnetic field signal can have a power of greater than 40W. Each applicator can further include a coil circuit configured to emit the high-power pulsed electromagnetic field signal, and an electromagnetic energy shield disposed between the drive circuitry and the coil circuit.