Electrical Therapeutic Systems Patents (Class 607/2)
  • Patent number: 10039918
    Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular helical liner disposed coaxially with the lumen within the insulative member. A pitch of the helical liner varies along the length of the lead. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 7, 2018
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Daniel J. Foster, Christopher R. Perrey, Andrew L. De Kock, Patrick Willoughby, Bryan A. Clark
  • Patent number: 10039461
    Abstract: Systems, devices, and methods are described for neuromonitoring. A minimum stimulus signal required to elicit a threshold neuromuscular response is determined by delivery of stimulus signals to tissue and detection of neuromuscular responses in muscle tissue. The strength of the delivered stimulus signals is varied, for example by adjusting the current amplitude or pulse width of the signals, and muscle responses are measure, for example by detecting EMG signals. The delivered stimuli and corresponding responses are then used to determine a stimulation threshold. The stimulation threshold may be used to indicate at least one of nerve proximity and pedicle integrity.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: August 7, 2018
    Assignee: Cadwell Laboratories, Inc.
    Inventor: John Cadwell
  • Patent number: 10035019
    Abstract: A positionally sensitive spinal cord stimulation apparatus and method using near-infrared (NIR) reflectometry are provided for automatic adjustments of spinal cord stimulation. The system comprises an electrode assembly with an integrated optical fiber sensor for sensing spinal cord position. The integrated optical fiber sensor, comprising a pair of optical elements for emitting light from an IR emitter and for collecting reflected light into a photodetector, determines a set of measured photocurrents. As the spinal cord changes position, the angles of incidence for light from the IR emitter and the measured optical intensities change. Electrode pulse characteristics are adjusted in real time, based on the set of measured optical intensities, to minimize changes in stimulation perceived by the patient during motion. The system includes automatic calibration of the optical fiber sensor when the patient is at rest, and a patient orientation detection.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: July 31, 2018
    Inventor: Erich W. Wolf, II
  • Patent number: 10035018
    Abstract: A method of treating a movement disorder using deep brain stimulation, the method comprising the step of inserting a lead having at least one electrode into the brain of a subject, the lead being inserted along a trajectory from the occipito-temporal or occipito-parietal regions, passing laterally to the posterior horn of the lateral ventricle to contact the subthalamic nucleus, the zona incerta or the globus pallidus.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: July 31, 2018
    Assignee: RENISHAW PLC
    Inventor: Steven Gill
  • Patent number: 10029102
    Abstract: A neuromodulation system and method of providing therapy to a patient. Electrical energy is delivered to the patient in accordance with a modulation parameter, thereby providing therapy to the patient, and the modulation parameter of the delivered electrical energy is varied over a period of time, such that the delivered electrical energy is continually maintained at a sub-threshold level throughout the period of time. The sub-threshold level may be referred to as a patient-perception threshold, which may be referred to as a boundary below which a patient does not sense delivery of the electrical energy. For example, in a spinal cord modulation system, the patient-perception threshold may be a boundary below which a patient does not experience paresthesia.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: July 24, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Que T. Doan, Jordi Parramon, Sridhar Kothandaraman, Christopher Ewan Gillespie, Sarvani Grandhe
  • Patent number: 10028730
    Abstract: A biopsy device includes a probe, a holster, and a tissue sample holder for collecting tissue samples. The probe includes a needle and a hollow cutter. The tissue sample holder includes a housing having one or more chambers that are configured to receive a removable tray including one or more prongs and a bulk chamber of a different volume than the one or more chambers. The housing is releasably engageable with the probe. Each tray prong is configured to receive a tissue sample communicated through the cutter lumen. The tray is removable from the housing, such as along an axial direction. The tissue sample holder is rotatable to successively index each chamber to the cutter lumen. The trays may be flexible, resilient, or rigid.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: July 24, 2018
    Assignee: Devicor Medical Products, Inc.
    Inventors: Kevin M. Fiebig, Jessica P. Leimbach, Kyle P. Moore, Andrew P. Nock
  • Patent number: 10016608
    Abstract: A system and method for locating an implantable tissue stimulation lead within a patient. A measurement indicative of a coupling efficiency between the tissue stimulation lead and tissue at a location is taken. The location of the tissue stimulation lead relative to the tissue is tracked. Coupling efficiency information based on the measurement from the monitoring device is generated, tracking information based on the tissue stimulation lead location is generated, and the coupling efficiency information and tracking information is concurrently conveyed to the user.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: July 10, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: David K. L. Peterson, Kerry Bradley
  • Patent number: 10004634
    Abstract: A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: June 26, 2018
    Inventor: Malik Y. Kahook
  • Patent number: 9993290
    Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. If it is determined that the uterus is not perforated, a patency test can be performed to determine that the uterine device is not clogged or embedded in tissue. If the uterus is intact and the device is not clogged or embedded in tissue, the uterus can be treated with the uterine device, e.g., uterine ablation. Systems for performing these methods are also disclosed.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: June 12, 2018
    Assignee: AEGEA MEDICAL INC.
    Inventors: Uriel Hiram Chee, Robert Bilgor Peliks, Hugh Edward Magen, Donnell William Gurskis, Steven Robert Bacich
  • Patent number: 9987481
    Abstract: An electrode assembly that includes an electrically conductive layer, a first impedance reduction system, and a second impedance reduction system. The electrically conductive layer forms an electrode portion of the electrode assembly and a first surface to be placed adjacent a person's skin. The first impedance reduction system is configured to dispense a first amount of an electrically conductive gel onto the first surface of the electrically conductive layer in response to a first activation signal. The second impedance reduction system is configured to dispense a second amount of the electrically conductive gel onto the first surface of the electrically conductive layer in response to a second activation signal.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: June 5, 2018
    Inventors: Thomas E. Kaib, Shane S. Volpe, Emil Oskin
  • Patent number: 9987493
    Abstract: A medical electrical stimulator provides selective control of stimulation via a combination of two or more electrodes coupled to respective regulated current paths and one or more electrodes coupled to unregulated current paths. Constant current sources may control the current that is sourced or sunk via respective regulated current paths. An unregulated current path may sink or source current to and from an unregulated voltage source that serves as a reference voltage. Unregulated electrodes may function as unregulated anodes to source current from a reference voltage or unregulated cathodes to sink current to a reference voltage.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: June 5, 2018
    Assignee: Medtronic, Inc.
    Inventors: Nathan A. Torgerson, Matthew J. Michaels
  • Patent number: 9974452
    Abstract: Embodiments herein describe a user device that includes a dual purpose coil (or inductor) used when performing inductive sensing and when transferring electrical power to the user device. When performing inductive sensing, the user device couples the coil to a sensing circuit which measures a resistivity of a lossy material inductively coupled to the coil. In one embodiment, the user device may be worn on the wrist of the user so that the sensing circuit measures the resistivity corresponding to the flow of blood in an artery or vein. By monitoring changes in the resistivity of the blood or artery, the user device can identify the heartbeat of the user. When transferring electrical power, the user device couples the coil to a charging circuit which receives the power provided by an external charging device that is inductively coupled to the coil.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: May 22, 2018
    Inventors: Marshall J. Bell, Jr., Jeffrey S. Lillie
  • Patent number: 9974947
    Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: May 22, 2018
    Assignee: Case Western Reserve University
    Inventors: Dominique M. Durand, Brian Wodlinger
  • Patent number: 9974344
    Abstract: A wearable safety device assembly is disclosed. The assembly includes at least one sensor configured to obtain one or more signals from a user. One of the at least one sensors comprises a vestibular (and startling/surprise related) motion sensor specially configured to obtain vestibular (and startling/surprise related) signals. Vestibular (and startling/surprise related) data indicative of a user's vestibular (and startling/surprise related) state is extracted from the one or more signals and used to determine whether a user is undergoing an event such as a fall or a startling movement. When it is determined that a user is undergoing an event, the processor of the wearable safety device transmits an activation signal to the safety device. Optionally, the processor may transmit data and information related to the vestibular (and startling/surprise related) system and recorded signals to a data repository.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: May 22, 2018
    Assignee: GraceFall, Inc.
    Inventors: Allon Guez, Helen Guez
  • Patent number: 9968329
    Abstract: A processing device detects a medical device and sends an audio wake-up signal to the medical device, wherein the audio wake-up signal causes the medical device to transition from a low power state to a higher power state. The processing device receives a diagnostic audio signal from the medical device after sending the audio wake-up signal. The processing device processes the diagnostic audio signal to determine medical information of a patient, the medical information comprising at least one of heart beat information or breathing information of the patient. The processing device performs at least one of storing the medical information or transmitting the medical information to a remote computing device.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: May 15, 2018
    Assignee: CliniCloud Inc.
    Inventors: Hon Weng Chong, Lain Cai Cai, An Lin, Robert James Skillington
  • Patent number: 9968775
    Abstract: Tether apparatus may be used to replace an implanted lead extension with a replacement lead extension without tunneling or the use of tunneling tools.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: May 15, 2018
    Assignee: MEDTRONIC, INC.
    Inventors: Peter Appenrodt, Daniel Schmitz, Paul van Venrooij
  • Patent number: 9962542
    Abstract: Systems and methods for deep brain electrode placement and deep brain stimulation (DBS) for treatment of conditions such as obesity are disclosed. In one example approach, during placement of a deep brain stimulating electrode in a target region of the brain of a patient, a temperature of brown adipose tissue (BAT) may be monitored, e.g., via a supraclavicular temperature sensor implanted in the patient, and used to identify an optimal location of electrode stimulation which causes an increase in BAT temperature. Additionally, BAT temperature measurements may be used to provide regulated closed-loop control to increase efficiency of DBS while reducing energy consumption of the pulse generator. Further, core temperature measurements may be obtained from the electrode in the brain and used to adjust DBS.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: May 8, 2018
    Assignee: Oregon Health & Science University
    Inventors: Kim Burchiel, Christopher J. Madden, Shaun F. Morrison
  • Patent number: 9962544
    Abstract: An electrode connector assembly for use in transcutaneous electrical stimulation includes a flexible web extending in a plane and first, second, third and fourth electrode connectors carried by the web and spaced from each other about the web in the plane. The electrode connector assembly further includes an electrical connector and first, second, third and fourth conductors electrically coupling the respective first, second, third and fourth electrode connectors to the electrical connector.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: May 8, 2018
    Assignee: GI Therapies Pty Ltd
    Inventors: Bridget Rae Southwell, David Fisher, Rod Wiebenga, Lisa Tjernberg
  • Patent number: 9962543
    Abstract: In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: May 8, 2018
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Claudio A. Feler, John H. Erickson
  • Patent number: 9962475
    Abstract: Disclosed herein are heart pumps that can include a catheter body and an impeller coupled with a distal end of the catheter body. The impeller can include a tip that is resealable or that includes a resealable member. The heart pump can also include a diffuser disposed between the distal end of the catheter body and the impeller, wherein the diffuser includes a flow directing surface.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: May 8, 2018
    Inventors: Robert L. Campbell, Jeremy J. Koncoski, Thomas M. Mallison, Mark W. McBride, Daniel Metrey, Eric C. Myer, Kevin J. Powell, Adam Roslund, Daniel A. Walters, William James Repka, Phyllis Yuen
  • Patent number: 9962546
    Abstract: A CFS system includes self-adhesive, disposable pads. Each pad is combined with a sealed, cleanable battery/controller pod and then placed on the body where needed. The battery/controller pod preferably has wireless capability, such as Bluetooth® capability. The patient can download an application to a smartphone or similar mobile device to control the pods.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: May 8, 2018
    Assignee: Meagan Medical, Inc.
    Inventors: William J. Carroll, Mark Edward Schoening, Patrick Allen Scranton, William Richard Huseby
  • Patent number: 9956421
    Abstract: Designs and methods of construction for an implantable medical device employ an internal support structure. The single-piece support structure holds various electronic components such as a communication coil and a circuit board, and further is affixed to a battery, thus providing a subassembly that is mechanically robust. The support structure further provides electrical isolation between these and other components. A method of construction allows for the subassembly to be adhered to a case of the implantable medical device at the support structure, and possibly also at the battery, without electrically shorting the battery to the case.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: May 1, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Navin N. Bunyan, Robert R. Tong, Jeffery Van Funderburk
  • Patent number: 9959471
    Abstract: A system for monitoring a patient in a patient area having one or more detection zones, the system comprising one or more cameras, a user interface, and a computing system configured to receive a chronological series of frames from the one or more cameras, identify liquid candidates by comparing a current frame with a plurality of previous frames of the chronological series, determine locations of the liquid candidates, identify thermal signatures of the liquid candidates, determine types of liquids of the liquid candidates based on the locations and thermal signatures of the liquid candidates, and generate an alert with the user interface corresponding to the determined types of liquids.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: May 1, 2018
    Assignee: CareView Communications, Inc.
    Inventors: Steven Gail Johnson, Derek del Carpio, Kenneth W. Chapman
  • Patent number: 9956393
    Abstract: The disclosed wearable device modulates a patient's gastric emptying time and/or gastric retention time. The wearable device includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 dermatome to a T12 dermatome or meridian of the patient, a C5 to a T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: May 1, 2018
    Assignee: Elira, Inc.
    Inventors: Raul E. Perez, Peter I. Hong, Steven Diianni, Luis Jose Malave, Brad Stengel
  • Patent number: 9956409
    Abstract: Spinal cord stimulation (SCS) system having a recharging system with self alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsource, and control through software on Smartphone/mobile device and tablet hardware during trial and permanent implants. SCS system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) providing concurrent, but unique stimulation fields. SCS system can include a replenishable power source, rechargeable using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery, can charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. A bi-directional telemetry link informs the patient or clinician the status of the system, including the state of charge of the IPG battery.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: May 1, 2018
    Assignee: Globus Medical, Inc.
    Inventors: Saif Khalil, Raghavendra Angara, Miles Curtis, Christopher Biele, Daniel Fellmeth
  • Patent number: 9943683
    Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: April 17, 2018
    Assignee: DJO, LLC
    Inventors: Thomas Jerome Bachinski, Richard Paul Shindley, Dennis Lutz
  • Patent number: 9925379
    Abstract: A computer implemented method and system is provided for managing neural stimulation therapy. The method comprises under control of one or more processors configured with program instructions. The method delivers a series of candidate stimulation waveforms having varied stimulation intensities to at least one electrode located proximate to nervous tissue of interest. A parameter defines the candidate stimulation waveforms is changed to vary the stimulation intensity. The method identifies a first candidate stimulation waveform that induces a paresthesia-abatement effect, while continuing to induce a select analgesic effect. The method further identifies a second candidate stimulation waveform that does not induce the select analgesic effect. The method sets a stimulation therapy based on the first and second candidate stimulation waveforms.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: March 27, 2018
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Alexander Kent, Richard Williamson
  • Patent number: 9913979
    Abstract: Multiple designs, systems, methods and processes for control using electrical signals recorded from clinically paralyzed muscles and nerves are presented. The discomplete neural prosthesis system and method for clinically paralyzed humans utilizes a controller. The controller is adapted to receive a volitional electrical signal generated by the human that is manifest below the lesion that causes the clinical paralysis. The controller uses at least the volitional electrical signal to generate a control signal that is output back to a plant to change the state of the plant, which in one aspect is one or more of the user's paralyzed muscles to achieve a functional result or to devices in the environment around the user that are adapted to receive commands from the controller.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: March 13, 2018
    Assignee: Case Western Reserve University
    Inventors: Christa Wheeler Moss, Paul Hunter Peckham
  • Patent number: 9907954
    Abstract: Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: March 6, 2018
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 9901710
    Abstract: Steering engagement catheter devices, systems, and methods of using the same for accessing a tissue, including internal and external tissues of a heart, are disclosed. In at least one embodiment, a steering engagement catheter is provided, comprising an elongated tube having a proximal end, a distal end, and a first wall positioned circumferentially along a length of the elongated tube, the elongated tube configured such that a delivery catheter is capable of at least partial insertion into the elongated tube, at least one steering wire having a proximal end and a distal end, the distal end of the at least one steering wire coupled to the first wall of the elongated tube at or near the distal end of the elongated tube, and a controller operably coupled to the at least one steering wire at or near the proximal end of the at least one steering wire.
    Type: Grant
    Filed: August 13, 2008
    Date of Patent: February 27, 2018
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 9895539
    Abstract: Systems for disease treatment using electrical stimulation are disclosed. A representative method for treating a patient includes changing an activity, expression, or both activity and expression of a fast sodium channel, a glial cell, or both a fast sodium channel and a glial cell of the patient by applying to a target neural population of the patient an electrical therapy signal having a frequency in a frequency range of 1.5 kHz to 100 kHz.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: February 20, 2018
    Assignee: Nevro Corp.
    Inventors: Gary Heit, Bradford Evan Gliner
  • Patent number: 9895541
    Abstract: A method for controlling a position of a patient's tongue includes attaching at least one electrode to the patient's Hypoglossal nerve and applying an electric signal through the electrode to at least one targeted motor efferent located within the Hypoglossal nerve to stimulate at least one muscle of the tongue. Methods may also include the use of more than one contact to target more than one motor efferent and stimulating more than one muscle. The stimulation load to maintain the position of the tongue may be shared by each muscle. The position of the patient's tongue may be controlled in order to prevent obstructive sleep apnea.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: February 20, 2018
    Inventors: Paul M. Meadows, Marcelo G. Lima, Faisal N. Zaidi
  • Patent number: 9872999
    Abstract: A cardiac pacing system comprising one or more leadless cardiac pacemakers configured for implantation in electrical contact with a cardiac chamber and configured to perform cardiac pacing functions in combination with a co-implanted implantable cardioverter-defibrillator (ICD). The leadless cardiac pacemaker comprises at least two leadless electrodes configured for delivering cardiac pacing pulses, sensing evoked and/or natural cardiac electrical signals, and bidirectionally communicating with the co-implanted ICD.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: January 23, 2018
    Assignee: Pacesetter, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 9875340
    Abstract: Systems and methods disclosed herein provide efficacious pain management therapies based on delivery of physical medicine(s) via computer-implemented systems. Patient information comprising patient pain symptoms, patient physiological measurements, patient demographics, and other information is received at a pain therapy device. The patient information is compared with pain analytics data compiled on a plurality of individuals to determine a personalized pain management therapy. The personalized pain management therapy is applied via a combination of thermoceuticals, electroceuticals, ultrasound, and several other forms of physical medicine. Sensors coupled to the pain therapy device measure changes in physiological data resulting from the pain management therapy. The personalized pain management therapy can be adjusted based on the changes in the physiological data and/or patient feedback.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: January 23, 2018
    Inventor: Krishnamohan Sharma
  • Patent number: 9861810
    Abstract: Thermal drawing processes can be used to make multifunctional, high-resolution neural probes for neural recording and stimulation. An exemplary neural probe may include one or more conductive fibers or microelectrodes coated with two or more layers of insulating material, at least one of which is partially etched to expose a tip at the neural probe's distal end. The conductive fibers conduct electrical signals (e.g., neural spikes or electrical stimulation) between the tip and the neural probe's proximal end. Optional optical and fluidic waveguides may guide light and fluid, respectively, between the tip and the proximal end. A neural probe may be flexible enough for long-term (chronic) implantation in neural tissue (e.g., the brain) without excessive tissue damage, even during movement of the brain in the skull. The probe may be made from biocompatible materials, such as insulating and conductive polymers, that have negligible (insignificant) interaction with the surrounding tissue.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: January 9, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Polina Olegovna Anikeeva, Xiaoting Jia, Chi Lu, Andres Canales, Ulrich Paul Froriep, Christina Myra Tringides, Yoel Fink
  • Patent number: 9855431
    Abstract: Various device embodiments may comprise an implantable medical device for implantation in a body and for applying neural stimulation to a neural target in the body. The device may comprise a neural stimulation electrode configured for use in stimulating the neural target, a neural stimulator configured to deliver neural stimulation through the electrode to the neural target, a sensor configured to sense a physiological response to stimulation of motor fibers at the neural target, and a controller operatively connected to the neural stimulator to control the neural stimulation and operatively connected to the sensor to receive a signal indicative of the physiological response. The controller may be configured to detect a potential neural injury and perform an action in response to the detected potential neural injury.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: January 2, 2018
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Jason J. Hamann, Stephen Ruble
  • Patent number: 9855435
    Abstract: The present disclosure provides leadless pacemaker systems and methods. A leadless pacemaker includes a battery subassembly, a feedthrough subassembly, and an electronics subassembly coupled between the battery subassembly and the feedthrough subassembly, the electronics subassembly including an electronics package, and a housing configured to provide a hermetic seal and comprising a first retaining feature and a second retaining feature configured to secure the electronics package within the housing.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: January 2, 2018
    Assignee: PACESETTER, INC.
    Inventors: Kavous Sahabi, Arees Garabed
  • Patent number: 9855439
    Abstract: High frequency cardiac arrhythmias and fibrillations are terminated by electric field pacing pulses having an order of magnitude less energy than a conventional cardioversion or defibrillation energy. The frequency and number of the pulses are selected based on a frequency analysis of a present high frequency cardiac arrhythmia or fibrillation. The energy of the pulses is selected from 1/400 to ½ of the conventional defibrillation energy, and the amplitude of the electric field pacing pulses are selected such as to activate a multitude of effective pacing sites in the heart tissue per each pacing electrode. The number and locations of the effective pacing sites in the heart tissue are regulated by the amplitude of the electric field pacing pulses, and by an orientation of the electric field of the pulses.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: January 2, 2018
    Inventors: Valentin Krinski, Eberhard Bodenschatz, Stefan Luther
  • Patent number: 9839466
    Abstract: Devices and methods are provided for ablational treatment of regions of the digestive tract in post-bariatric surgery patients who fail to achieve or maintain the desired weight loss. Bariatric procedures include Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy. These procedures reconstruct gastrointestinal tract features, creating pouches, stoma, and tubes that restrict and/or divert the digestive flow. Post-surgical dilation of altered structures is common and diminishes their bariatric effectiveness. Ablation of compromised structures can reduce their size and compliance, restoring bariatric effectiveness. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: December 12, 2017
    Assignee: Covidien LP
    Inventors: David S. Utley, John de Csepel
  • Patent number: 9839577
    Abstract: An auricular peripheral nerve field stimulator system includes an electrical stimulation device for generating electrical stimulation signals and a plurality of therapy electrodes each electrically coupled to the electrical stimulation device and each including a plurality of needles for percutaneous insertion into an auricle of a human ear near at least one neural vascular bundle located therein. In some embodiments, at least one reference electrode electrically is coupled to the electrical stimulation device and includes at least one needle for percutaneous insertion into or adjacent the auricle to provide a ground reference for the electrical stimulation device. The generated electrical stimulation signals are, in any case, delivered by the percutaneously inserted needles to stimulate an auricular peripheral nerve field within the auricle.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: December 12, 2017
    Assignee: Innovative Health Solutions, Inc.
    Inventors: Christopher R. Brown, Gary M. Peterson
  • Patent number: 9833617
    Abstract: An insulated electrode system for delivering a plurality of tumor treating electromagnetic fields including an array of electrode elements for proximate location on a body of a patient. Each electrode element of the array having an insulation layer. Each electrode element being independently electrically accessible and configured to be dynamically assigned to emanate an electromagnetic field relative to at least one other of said electrode elements.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: December 5, 2017
    Assignee: Loyalty Based Innovations, LLC
    Inventors: Peter F. Travers, Ken Watkins, Timothy VanderMey
  • Patent number: 9827040
    Abstract: Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation, etc., in target neural fibers. In some embodiments, the intravascular PEF system comprises a catheter having a pair of bipolar electrodes for delivering the PEF, with a first electrode positioned on a first side of an impedance-altering element and a second electrode positioned on an opposing side of the impedance-altering element. A length of the electrodes, as well as a separation distance between the first and second electrodes, may be specified such that, with the impedance-altering element deployed in a manner that locally increases impedance within a patient's vessel, e.g.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: November 28, 2017
    Assignee: Medtronic Adrian Luxembourg S.a.r.l.
    Inventors: Denise Zarins, Nicolas Zadno, Benjamin J. Clark, Erik Thai
  • Patent number: 9827422
    Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: November 28, 2017
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Changfang Zhu
  • Patent number: 9802042
    Abstract: A method for providing electrical stimulation to a user as a user performs a set of tasks during a time window, the method comprising: providing an electrical stimulation treatment, characterized by a stimulation parameter and a set of portions, to a brain region of the user in association with the time window; for each task of the set of tasks: receiving a signal stream characterizing a neurological state of the user; from the signal stream, identifying a neurological signature characterizing the neurological state associated with the task; and modulating the electrical stimulation treatment provided to the brain region of the user based upon the neurological signature, wherein modulating comprises delivering a portion of the set of portions of the electrical stimulation treatment to the brain region of the user, while maintaining an aggregate amount of the stimulation parameter of the treatment provided during the time window below a maximum limit.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: October 31, 2017
    Assignee: Halo Neuro, Inc.
    Inventors: Brett Wingeier, Daniel S. Chao, Lee Von Kraus, Amol Sarva, Sophia Sanchez
  • Patent number: 9802058
    Abstract: A transcranial magnetic stimulation coil which is location-specific for medial brain regions or lateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements are distributed around a central axis of the coil.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: October 31, 2017
    Assignee: BRAINSWAY, LTD.
    Inventors: Abraham Zangen, Yiftach Roth
  • Patent number: 9802049
    Abstract: Apparatus and methods for stimulating tissue employing local current imbalance to facilitate more effective stimulation regimens.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: October 31, 2017
    Inventor: Kerry Bradley
  • Patent number: 9795450
    Abstract: Apparatus is provided for ablating cardiac tissue of a subject. The apparatus comprises an inflatable element, configured to be transthoracically placed within a pericardial region of the subject and a reflection-facilitation element, configured to deliver a fluid to the pericardial region, such that a portion of the fluid is disposed within the inflatable element, and another portion of the fluid is disposed outside of the inflatable element and inside the pericardial region. The apparatus additionally comprises at least one ultrasound transducer, configured to be transcatheterally placed in a heart chamber of the subject, and to apply ultrasound energy such that at least a portion of the applied energy is reflected by the fluid. Other embodiments are also described.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: October 24, 2017
    Inventors: Liat Tsoref, Yossi Gross
  • Patent number: 9795795
    Abstract: Some embodiments relate to a device for generating stimulation signals, comprising: a stimulation delivery circuit; a first component to monitor charge delivered in at least one charge pulse via the stimulation delivery circuit; and a second component to ensure delivered charge substantially corresponds to charge of a charge pulse intended to be delivered by the stimulation delivery circuit. In some embodiments, the device may further comprise a charge setting circuit responsive to a charge pulse setting signal, such as a constant current of fixed pulse width, to set the charge of the charge pulse intended to be delivered.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: October 24, 2017
    Assignee: The Bionics Institute of Australia
    Inventors: Peter Misha Seligman, Hugh Joseph McDermott
  • Patent number: 9782597
    Abstract: A lead extension at least one lead extension body; terminals disposed along one end portion of the lead extension body(ies); a lead extension connector disposed along another end portion of the lead extension body(ies); and conductors electrically coupling the connector contacts in the lead extension connector to the terminals. The lead extension connector can include lead channels with non-straight paths to facilitate retention of leads. Alternatively, the lead extension connector can include one or more stretchable boots to each receive a lead when stretched and to grip the lead when relaxed. Alternatively, the lead extension connector can have two connector bodies with a pin channel and pin, respectively. When the pin is inserted into the pin channel, the pin compresses a portion of the connector body against the lead to retain the lead within the connector.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: October 10, 2017
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Christopher Shanahan, Geoffrey Abellana Villarta
  • Patent number: 9775671
    Abstract: Electric field delivery and ablation of target tissue regions, including cancerous cells and solid tumors. Methods and systems include delivering an electric field to a target tissue, and may include positioning a first electrode or plurality to at least partially define a first treatment volume in the target tissue; positioning a second electrode or plurality to at least partially define a second treatment volume, the first volume is disposed in the second volume; and establishing a first current flow extending through the first volume and a second current flow extending through the second volume.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: October 3, 2017
    Assignee: LaZure Scientific, Inc.
    Inventor: Larry Azure