Electrical Therapeutic Systems Patents (Class 607/2)
  • Patent number: 11039888
    Abstract: Systems and methods are described for planning of catheter ablation procedures, and in particular for planning of the placement of lesions and/or parameters used in ablation. In some embodiments, planning is based on thermal and/or dielectric simulation of lesions, individualized to the anatomy of the particular patient. Optionally, a plan comprises planning of a path along which an ablation lesion is to be formed, the ablation lesion optionally comprising one or more sub-lesions. The plan is optionally optimized for one or more criteria including, for example: minimization of path length, minimization of sub-lesion number, simplification of catheter maneuvering, avoidance of collateral damage to non-target tissue, access to the target dependent on anatomy shape and/or catheter mechanics, and/or features of the target anatomy such as tissue wall thickness and/or fiber direction.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: June 22, 2021
    Assignee: Navix International Limited
    Inventors: Yitzhack Schwartz, Zalman Ibragimov, Yehonatan Ben David, Eli Dichterman
  • Patent number: 11040197
    Abstract: Techniques are described for determining a voltammogram that characterizes a result of a fast-scan cyclic voltammetry process. The FSCV process can be performed using a sensing apparatus at least partially immersed in a volume of blood of a mammal. A system can process the voltammogram to determine a concentration of a neurochemical in the volume of blood of the mammal.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: June 22, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kip A. Ludwig, Kendall H. Lee, Kevin E. Bennet, Evan N. Nicolai, Anders J. Asp
  • Patent number: 11019991
    Abstract: The invention is a method of automatically adjusting a visual prosthesis electrode array to the neural characteristics of an individual patient. By recording electrically evoked responses to a predetermined input stimulus, one can alter that input stimulus to the needs of an individual patient. A minimum input stimulus is applied to a patient, followed by recording an electrically evoked response to the input stimulus. By gradually increasing stimulus levels, one can determine the minimum input that creates a neural response, thereby identifying the threshold stimulation level. One can further determine a maximum level by increasing stimulus until a predetermined maximum neural response is obtained.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 1, 2021
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J Greenberg, Gislin Dagnelie, Hendrik Christiaan Stronks
  • Patent number: 11020592
    Abstract: A system for providing electrical stimulation to a patient includes a processor configured to: provide a time-ordered arrangement of multiple stimulation instances, where each of the stimulation instances is configured to produce a different stimulation field from each other stimulation instance in the arrangement; provide an ON/OFF switch pattern that includes alternating ON periods and OFF periods; generate an intermittent stimulation program that corresponds to repetition of the arrangement of stimulation instances with omission of each of the stimulation instances occurring during the OFF periods; and initiate a signal that provides a pulse generator with instructions that enable the pulse generator to generate stimulation according to the intermittent stimulation program using an electrical stimulation lead coupled to the pulse generator.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: June 1, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Danil Tyulmankov, Hemant Bokil, Peter Alexander Tass
  • Patent number: 11020591
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A stimulator comprises a contact surface for contacting an outer skin surface of a patient and a pulse generator coupled to the contact surface. The pulse generator is configured for attachment and electrical coupling to a mobile device configured to receive a wireless signal, such as a mobile phone. The pulse generator is further configured to generate an electrical impulse and to transmit the electrical impulse through the contact surface and the outer skin surface of the patient to modulate a nerve within the patient.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: June 1, 2021
    Assignee: ELECTROCORE, INC.
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Patent number: 11013922
    Abstract: A system for delivering electrical pulse stimulation to a subject includes a remote control device configured to at least intermittently transmit temporal pulse pattern programming and a stimulation device comprising a control interface, at least one electrode in electrical communication with the control interface, and an input device in at least intermittent communication with the remote control device to receive the temporal pulse pattern programming. The stimulation device is configured to deliver electrical pulse stimulation to a subject via the at least one electrode according to the temporal pulse pattern programming.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: May 25, 2021
    Assignee: Duke University
    Inventors: Warren M. Grill, Tianhe Zhang
  • Patent number: 11003682
    Abstract: Embodiments are disclosed for a visualization system that facilitates exploration and analysis of large sets of data by providing for synchronized, independent visualizations of metrics or event-derived value sets. The visualizations can reflect a variety of data, including pre-prepared metrics, event-derived values, or a combination thereof. Global parameter controls can enable synchronized interaction with multiple visualizations, such as modifying parameters of respective visualizations with a single input. Local parameter controls can enable interaction with an individual visualization, independent of interaction with other visualizations. A variety of tools and interfaces are provided to manipulate the visualizations to facilitate analysis across a variety of metrics within a single interface.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: May 11, 2021
    Assignee: Splunk Inc.
    Inventors: Michael Porath, Finlay Cannon, Jonathan Ng, Thomas Haggie
  • Patent number: 10987243
    Abstract: A method of detecting detachment of an ostomy device from a patient includes providing, in the ostomy device, a first electrode separated from the patient by an adhesive that attaches the ostomy device to the patient, where a first capacitor is formed between the first electrode and the patient. The method includes applying a signal to an electrical circuit that includes the first capacitor, and detecting changes in a capacitance value of the first capacitor based on frequency responses of the electrical circuit to the signal. The method additionally includes activating an alarm based upon detecting the changes in the capacitance value of the first capacitor.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: April 27, 2021
    Assignee: Coloplast A/S
    Inventors: Carsten Thirstrup, Daniel Nilsson, Henrik Pranov, Lars Lading
  • Patent number: 10987514
    Abstract: Provided is a system and method for cavernosal neuromodulation as directed by a wireless remote controller and power supply. The system including: an implantable lead having at least one electrode structured and arranged to be disposed proximate to the cavernous nerve in a penis; a portable power supply; and a controller having wireless communication electronics and control circuitry associated with the wireless communication electronics structured and arranged to wirelessly couple the power supply to the at least one electrode, the controller further structured and arranged to permit a user to select at least one instruction set for the at least electrode. The controller and power supply may be provided by a control ring. An associated method of use is also provided.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: April 27, 2021
    Inventors: Kenneth M. Peters, Larry T. Sirls
  • Patent number: 10981008
    Abstract: Delivery devices, systems, and methods for delivering implantable leadless pacing devices are disclosed. An example delivery device may include a proximal section including a deflection mechanism for deflecting the proximal section, and a distal holding section extending distally of a distal end of the proximal section and defining a cavity therein for receiving an implantable leadless pacing device. The delivery device may include more than one deflection mechanism for deflecting the proximal section at multiple deflection regions. The delivery device may include more than one tubular member that are translatable relative to one another, and the one or more tubular members may include fixed curve portions. The delivery device may include an atraumatic or bumper tip at the distal end of the holding section.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: April 20, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Brian L. Schmidt, Benjamin J. Haasl, Keith R. Maile, Eric Bielefeld, Dana Sachs, Adwait Kumar, Indaka Gunasekara
  • Patent number: 10980932
    Abstract: The present invention is directed towards methods for therapeutically targeting circulating tumor cells during hemodialysis.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 20, 2021
    Assignee: Roseman University of Health Sciences
    Inventors: Thuc T. Le, Ranjana Mitra, Yasuyo Urasaki, Oscar B. Goodman
  • Patent number: 10981013
    Abstract: A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: April 20, 2021
    Assignee: The Cleveland Clinic Foundation
    Inventors: J. Luis Lujan, Ashutosh Chaturvedi, Cameron McIntyre
  • Patent number: 10967170
    Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: April 6, 2021
    Assignee: DJO, LLC
    Inventors: Thomas Jerome Bachinski, Richard Paul Shindley, Dennis Lutz
  • Patent number: 10967184
    Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. The implanted stimulation device includes a physiological sensor for recording the patient's response to the neurostimulation therapy on an ambulatory basis over extended periods of time.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: April 6, 2021
    Assignees: LivaNova USA, Inc., East Tennessee State University
    Inventors: Imad Libbus, Badri Amurthur, Bruce H. KenKnight, Jeffrey L. Ardell
  • Patent number: 10953232
    Abstract: A magnetic resonance imaging (MRI) telemetry arrangement and process for a cochlear implant system are described. Electrode current is measured that is induced in a cochlear implant electrode lead during an MRI process performed on an implanted patient. An MRI telemetry signal for an external telemetry sensor is then output based on the measured electrode current.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: March 23, 2021
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventor: Erwin Hochmair
  • Patent number: 10940316
    Abstract: A neurostimulation system provides for capture verification and stimulation intensity adjustment to ensure effectiveness of vagus nerve stimulation in modulating one or more target functions in a patient. In various embodiments, stimulation is applied to the vagus nerve, and evoked responses are detected to verify that the stimulation captures the vagus nerve and to adjust one or more stimulation parameters that control the stimulation intensity.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: March 9, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Juan Gabriel Hincapie Ordonez, David J. Ternes, Jason J. Hamann, Stephen B. Ruble
  • Patent number: 10940314
    Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: March 9, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Changfang Zhu
  • Patent number: 10932503
    Abstract: A urine powered garment has a shirt and trousers. A collector positioned beneath the trousers is adapted to collect urine. A container is located below and coupled to the collector. A converter dis-associates the constituent elements of the urine within the container to create electrical energy. A pouch receives urine from the container. The pouch has a top opening above and a drain tube below. The drain tube couples the pouch and the converter. A source of potential is adapted to receive electrical potential and to store the received electrical potential until accessed. A super-capacitor couples the converter and the source of potential. The super-capacitor converts the output of the converter prior to feeding to the source of potential.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: March 2, 2021
    Inventor: Martha Fallis
  • Patent number: 10933229
    Abstract: A facial skin care device and a method of operating the same are disclosed. The facial skin care device comprises an oral insertion module configured to have a structure inserted in an oral cavity and include one or more oral electrodes contacted with a skin in the oral cavity, and a main body configured to include a main electrode connected electrically to at least one of the oral electrode on an outer surface of a facial skin and a current generation unit which is connected to the main electrode and generates current for applying electrical stimulation to the facial skin.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: March 2, 2021
    Assignee: MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION
    Inventor: Jung Kuk Kim
  • Patent number: 10918865
    Abstract: A method for stimulating nerve fibers to treat a condition in a patient first involves identifying carotid sinus nerve afferent fibers in a first side of the patient's neck and identifying cardiac-specific vagal nerve afferent fibers in the first side of the patient's neck. The method further involves placing a first multipolar electrode device around the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers. Finally, the method involves stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers, using the first multipolar electrode device. This method may be performed on a second side of the neck as well.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: February 16, 2021
    Assignee: BAROLOGICS, INC.
    Inventors: Dimitrios Georgakopoulos, Molly Wade
  • Patent number: 10918867
    Abstract: Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: February 16, 2021
    Assignee: Nevro Corp.
    Inventors: Andre B. Walker, Zi-Ping Fang, Anthony V. Caparso
  • Patent number: 10905890
    Abstract: An energy harvester converts into electrical energy the external stresses applied to the implant at the heartbeat rhythm. This harvester comprises an inertial unit and a transducer delivering an electrical signal that is rectified and regulated for powering the implant and charging an energy storage component. The charge level of the energy storage component is compared with a lower threshold to detect an insufficient charge, and a dynamic charging control circuit modifies, as and whenever necessary, and if the current patient's state allows it, a stimulation parameter in a direction liable to increase in return the mean level of the mechanical energy that is produced and harvested.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: February 2, 2021
    Assignee: CAIRDAC
    Inventor: Jean-Luc Bonnet
  • Patent number: 10894159
    Abstract: The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a combination of burst and tonic stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: January 19, 2021
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventor: Dirk De Ridder
  • Patent number: 10881863
    Abstract: Implantable medical devices such as leadless cardiac pacemakers may be configured to communicate using more than one mode of communication. For example, in some cases, an implantable medical device may be configured to communicate via conducted communication in some circumstances and to communicate via inductive communication in other circumstances. In some cases, the implantable medical device may be configured to switch between communication modes in order to improve communication.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: January 5, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Keith R. Maile, William J. Linder, Jacob M. Ludwig
  • Patent number: 10886677
    Abstract: Distal connector assemblies that are on the distal end of medical lead extensions provide increased rigidity by including a rigid holder that contains the electrical connectors. The electrical connectors are separated within the rigid holder by insulative spacers that may be individual items or may be formed from a compliant carrier that the electrical connectors may reside within where the carrier is positioned within the rigid holder. The rigid holder may also contain a set screw block defining set screw bore or the rigid holder may include an integral portion that defines a set screw bore. The integral portion may include a slot to allow a molding pin loaded with the electrical connectors and other components to be dropped into a cavity of the rigid holder. An overmold may be present to surround the rigid body containing the electrical connectors and insulative spacers.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: January 5, 2021
    Assignee: MEDTRONIC, INC.
    Inventors: Scott M. Hanson, Joseph P. Ricci, Adam J. Rivard, Jonathan C. Sell
  • Patent number: 10874857
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 29, 2020
    Assignee: ELECTROCORE, INC
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Patent number: 10870005
    Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level until a target T-wave alternans change from a baseline T-wave alternans is achieved.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: December 22, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Imad Libbus, Bruce H. KenKnight
  • Patent number: 10870002
    Abstract: A sensing device for detecting an artificially induced neuromuscular response within a limb of a subject includes a carrier material and a plurality of mechanical sensors. The carrier material is operative to be secured around a portion of the limb, and each of the plurality of mechanical sensors are coupled with the carrier material. Each mechanical sensor is positioned on the carrier material such that it is operative to monitor a mechanical response of a different muscle group of the limb. Each mechanical sensor then generates a respective mechanomyography output signal corresponding to the monitored mechanical response of its adjacent muscle group. These signals may then be communicated outbound from the device via communication circuitry provided on the device.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: December 22, 2020
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Christopher Wybo, Aashish Shah, Tarik Yardibi, Emir Osmanagic, Darren Scarfe
  • Patent number: 10870000
    Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: December 22, 2020
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Andrew B. Kibler, Marcelo Baru, Dirk Muessig
  • Patent number: 10850090
    Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. The peripheral nerve stimulator can be either a noninvasive surface stimulator or an implanted stimulator. Stimulation can be electrical, mechanical, or chemical. Stimulation can be delivered using either an open loop system or a closed loop system with feedback.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: December 1, 2020
    Assignee: CALA HEALTH, INC.
    Inventors: Kathryn H. Rosenbluth, Scott Lee Delp, John Paderi, Vijaykumar Rajasekhar, Tahel Altman
  • Patent number: 10842988
    Abstract: A method for implanting a medical lead. The method includes advancing a tunneling tool posteriorly proximate the caudal end of the sternum toward a first location. The tunneling tool is advanced superiorly underneath the sternum through the anterior mediastinum from the first location to a second location cranial to the first location. A guidewire is advanced from the first location to the second location. A medical lead is slid along at least a portion of the guidewire, the medical lead at least substantially spanning the distance between the first location and the second location.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: November 24, 2020
    Assignee: Medtronic, Inc.
    Inventors: Amy E. Thompson-Nauman, James K. Carney, Melissa G. T. Christie, Kenneth C. Gardeski
  • Patent number: 10835747
    Abstract: Auricular nerve stimulation techniques for addressing patient disorders, and associated systems and methods. A representative system includes a signal generator having instructions to generate an electrical therapy signal, at least a portion of the electrical therapy signal having a frequency at or above the patient's auditory frequency limit, an amplitude in an amplitude range from about 0.1 mA to about 10 mA, and a pulse width in a pulse width range from 5 microseconds to 30 microseconds. The system further includes at least one earpiece having a contoured outer surface shaped to fit against the skin of the patient's external ear, external ear canal, or both, the at least one earpiece carrying at least two transcutaneous electrodes positioned to be in electrical communication with the auricular innervation of the patient, e.g., the auricular vagal nerve.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: November 17, 2020
    Assignee: Vorso Corp.
    Inventors: Vivek K. Sharma, Konstantinos Alataris, Gary Heit, Jason Sutor, Pankaj Sunkeri
  • Patent number: 10841105
    Abstract: A method for providing a proof-of-work includes computing, by a verification computing device (VCD), a first linear feedback shift register sequence (LFSR-S) using a first polynomial having a first degree and computing, by the VCD, a second LFSR-S based on a second polynomial. A challenge, generated by the VCD and using elements of the second LFSR-S, is transmitted to the PCD. The PCD recursively computes all elements of the first LFSR-S by using the elements and coefficients of the second LFSR-S. A solution for the received challenge is computed based on the computed elements of the first LFSR-S. A proof-of-work is provided by verifying, by the VCD, the transmitted solution by: recomputing a solution to the challenge using initial state parameters and coefficients of the first LFSR-S, and comparing the computed solution of the PCD with the recomputed solution of the VCD.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: November 17, 2020
    Assignee: NEC CORPORATION
    Inventors: Jens-Matthias Bohli, Ghassan Karame, Frederik Armknecht
  • Patent number: 10835741
    Abstract: Disclosed herein is a screw-in lead implantable in the pericardium of a patient heart and a system for delivering such leads to an implantation location. The leads include a helical tip electrode and a curate body including a defibrillator coil with improved contact between the defibrillator coil and the patient heart. The delivery system includes a delivery catheter and lead receiving sheath disposed within the catheter. A fixation tine is disposed on one of the delivery catheter and the lead receiving sheath such that the delivery system may be anchored into the pericardium during fixation of the screw-in lead. In certain implementations, an implantable sleeve receives the leads to bias the defibrillator coil against the patient heart.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: November 17, 2020
    Assignee: Pacesetter, Inc.
    Inventors: Gene A. Bornzin, Devan Hughes, Keith Victorine, Zoltan Somogyi, Matthew Nojoomi, Ekaterina Tkatchouk, Xiaoyi Min
  • Patent number: 10828492
    Abstract: A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: November 10, 2020
    Inventor: Adi Mashiach
  • Patent number: 10828461
    Abstract: An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator wirelessly receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and wirelessly outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes wirelessly connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: November 10, 2020
    Assignee: Neuvana, LLC
    Inventors: Richard Cartledge, Daniel Cartledge, Ami Brannon, Kermit Falk, Gregory L. Mayback
  • Patent number: 10814128
    Abstract: A catheter includes first and second handles, first and second tubular members, and first and second electrodes. The first tubular member defines a channel therethrough and is coupled to and distally extends from the first handle. The second tubular member is coupled to and distally extends from the second handle. The second tubular member is slidably disposed within the channel of the first tubular member and defines a lumen therethrough. The first and second electrodes are configured to generate an electric field therebetween. The second handle is translatable relative to the first handle between a retracted position in which the second electrode is adjacent the first electrode and an extended position in which the second electrode is spaced apart from the first electrode.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: October 27, 2020
    Assignee: COVIDIEN LP
    Inventors: Tyler J. Eckwright, Katherine A. Herdina, Carol L. Shaffer
  • Patent number: 10806925
    Abstract: A muscle electrostimulation device includes: a main body; a power source stored in the main body; an electrode unit that receives power from the power source; a controller that controls the supply of power to the electrode unit; and an operation unit that changes a control mode of the controller. The electrode unit includes a first and a second electrode group. The first group extends from the main body to be disposed on a right hand side of a person with respect to a center line of the main body. The second group extends from the main body to be disposed on a left hand side of the person with respect to the center line when the device is attached to the abdomen. The first and the second electrode group can be electronically connected via the person and include four or more electrodes in total.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: October 20, 2020
    Assignee: MTG CO., LTD.
    Inventor: Tsuyoshi Matsushita
  • Patent number: 10806928
    Abstract: Auricular nerve stimulation techniques for addressing patient disorders, and associated systems and methods. A representative system includes a signal generator having instructions to generate an electrical therapy signal, at least a portion of the electrical therapy signal having a frequency at or above the patient's auditory frequency limit, an amplitude in an amplitude range from about 0.1 mA to about 10 mA, and a pulse width in a pulse width range from 5 microseconds to 30 microseconds. The system further includes at least one earpiece having a contoured outer surface shaped to fit against the skin of the patient's external ear, external ear canal, or both, the at least one earpiece carrying at least two transcutaneous electrodes positioned to be in electrical communication with the auricular innervation of the patient, e.g., the auricular vagal nerve.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: October 20, 2020
    Assignee: Vorso Corp.
    Inventors: Vivek K. Sharma, Konstantinos Alataris, Gary Heit, Jason Sutor, Pankaj Sunkeri
  • Patent number: 10792491
    Abstract: The problem of a potentially high amount of supra-threshold charge passing through the patient's tissue at the end of an Implantable Pulse Generator (IPG) program is addressed by circuitry that periodically dissipates only small amount of the charge stored on capacitances (e.g., DC-blocking capacitors) during a pulsed post-program recovery period. This occurs by periodically activating control signals to turn on passive recovery switches to form a series of discharge pulses each dissipating a sub-threshold amount of charge. Such periodic pulsed dissipation may extend the duration of post-program recovery, but is not likely to be noticeable by the patient when the programming in the IPG changes from a first to a second program. Periodic pulsed dissipation of charge may also be used during a program, such as between stimulation pulses.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: October 6, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Emanuel Feldman, Jordi Parramon, Goran N. Marnfeldt, Adam T. Featherstone
  • Patent number: 10786665
    Abstract: Digital-to-analog converter (DAC) circuitry for providing currents at electrodes of an Implantable Pulse Generator (IPG) is disclosed. The DAC circuitry includes at least one PDAC for sourcing current to the electrodes, and at least one NDAC for sinking current from the electrodes. The PDACs are powered with power supplies VH (the compliance voltage) and Vssh in a high power domain, and the NDACs are powered with power supplies Vcc and ground in a low power domain. VH may change during IPG operation, and Vssh preferably also changes with a fixed difference with respect to VH. Digital control signals to the PDACs are formed (and possibly converted into) the high power domain, and transistors used to build the PDACs are biased in the high power domain, and thus may also change with VH. This permits transistors in the PDACs and NDACs to be made from normal low-voltage logic transistors.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: September 29, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Goran N. Marnfeldt, Philip L. Weiss, Pujitha Weerakoon, David M. Wagenbach, Emanuel Feldman, Kiran K. Gururaj
  • Patent number: 10754803
    Abstract: A hardware based block moving controller of an active device such as an implantable medical device that provides electrical stimulation reads a parameter data from a block of memory and then writes the parameter data to a designated register set of a component that performs an active function. The block of memory may include data that specifies a size of the block of memory to be moved to the register set. The block of memory may also include data that indicates a number of triggers to skip before moving a next block of memory to the register set. A trigger that causes the block moving controller to move the data from the block of memory to the register set may be generated in various ways such as through operation of the component having the register set or by a separate timer.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: August 25, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Robert W. Hocken, Wesley A. Santa, Christopher M. Arnett, Jalpa S. Shah, Joel E. Sivula
  • Patent number: 10751539
    Abstract: The present disclosure relates to an active closed-loop medical system comprising at least one implantable medical device, at least one non-implanted component and at least a controller for controlling the implantable medical device, wherein the implantable medical device, the non-implanted component and the controller are connected for data exchange, wherein the implantable medical device, the non-implanted component and the controller forming in the active state a closed-loop system in such that the implantable medical device is controlled by the controller on the basis of the signals exchanged with the non-implanted component.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: August 25, 2020
    Assignee: GTX MEDICAL B.V.
    Inventors: Joachim Von Zitzewitz, Vincent Delattre, Bert Bakker, Grégoire Courtine
  • Patent number: 10751536
    Abstract: Systems for disease treatment using electrical stimulation are disclosed. A representative method for treating a patient includes changing an activity, expression, or both activity and expression of a fast sodium channel, a glial cell, or both a fast sodium channel and a glial cell of the patient by applying to a target neural population of the patient an electrical therapy signal having a frequency in a frequency range of 1.5 kHz to 100 kHz.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: August 25, 2020
    Assignee: Nevro Corp.
    Inventors: Gary Heit, Bradford Evan Gliner
  • Patent number: 10744208
    Abstract: A method of killing cells of a targeted cell type in a patient body that utilizes nanoparticles (10) having a first portion (12), which when exposed to a target portion (14) of a targeted cell type (16), binds to the target portion and a second portion (10A), joined to the first portion, and comprised of a low resistivity material. The nanoparticles are introduced into a contact area where they contact cells of the targeted cell type. Contemporaneously, the contact area is exposed to a varying magnetic field of insufficient strength to increase the temperature of any part of the patient body by more than ten degrees Celsius, but which creates a current (20) at the nanoparticles sufficient to disrupt function of the targeted cell type.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: August 18, 2020
    Inventor: Robert E. Sandstrom
  • Patent number: 10744338
    Abstract: A brassiere is configured to administer electromagnetic therapy to treat a cancerous tumor within a breast. The brassiere includes at least one cup, the cup within its walls at least two magnetic coils (also referred to herein as solenoid coils). Each solenoid coil is energized, when in therapeutic operation, with a distinct time-domain signal. The time domain signal consists of a series of summed sinusoidal waves from a power supply. The coils are oriented within the wall of the cup such that for any two coils a first magnetic coil and a second magnetic coil are oriented relative to each other so as to be nonparallel. The purpose of having two distinct coils is to focus resultant magnetic fields such that at a tumor site within a volume of breast tissue the cup encloses to form a local maximum formed by superposition within the cancerous tumor.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: August 18, 2020
    Inventor: Darin Cook
  • Patent number: 10737096
    Abstract: This disclosure relates to methods for modifying neural activity by applying electrical current to a neural tissue, e.g., in a transcranial DC stimulation procedure (tDCS), a transcranial AC stimulation procedure (tACS), a transcranial random noise stimulation procedure (tRNS), a deep brain stimulation procedure (DBS), a transcutaneous electrical nerve stimulation procedure (TENS), or the like. Historically, computed potential, electrical field, and/or current density distributions have been used to select the locations of the electrodes that apply the electrical current. In the present disclosure, a computed charge distribution on the bounding surface of one or more sulci filled with cerebrospinal fluid (CSF) is used in selecting the electrode locations. In one embodiment, the sulcus's bounding surface is divided into pixels and each pixel's charge is determined by the pixel functioning as a sensor for the charges surrounding it, including the charges of other pixels and the charges on the electrodes.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: August 11, 2020
    Inventor: Maurice M. Klee
  • Patent number: 10729914
    Abstract: An electromagnetic radiation treatment regime includes identifying a target area of a patient. In one embodiment, the target area is the vagus nerve. An electromagnetic radiation source, for example, a low frequency and/or radio frequency electromagnetic radiation source, is selected, along with treatment session parameters, such as, pulse frequency, pulse duration, electrical current, magnetic flux density, and/or treatment session exposure time. An amount of electromagnetic radiation is applied to the target area, and a response to the electromagnetic radiation in the target area is measured. Based on an evaluation of the measured response, the treatment parameters may be modified for one or more subsequent electromagnetic radiation treatment session.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: August 4, 2020
    Inventor: Jacob Zabara
  • Patent number: 10722282
    Abstract: A method for reshaping a nasal airway in a patient involves advancing an inflatable balloon of a reshaping device in an uninflated configuration into a nostril of the patient and between a nasal septum and a lateral wall of the nasal airway. The method then involves inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to contact nasal mucosa covering the nasal septum and the lateral wall, delivering energy from an energy delivery member attached to or inside of the inflatable balloon, and removing the reshaping device from the nasal airway.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: July 28, 2020
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10709888
    Abstract: An electrical stimulation lead includes a lead body; a terminal disposed along the proximal end portion of the lead body; a single electrode disposed at the distal end of the lead body; a conductor extending along the lead body and electrically coupling the terminal to the single electrode; and an adjustable sheath disposed over a portion of the lead body to cover a selected portion of the single electrode by displacing the sheath forwards or backwards relative to the single electrode to control a size of a portion of the electrode exposed for stimulation of tissue. Another electrical stimulation lead has a low-profile distal portion that has a smaller lateral width in at least one direction than a remainder of the lead body. Yet another arrangement includes a guidewire with a mapping electrode to map a region around a peripheral nerve prior to implantation of an electrical stimulation lead.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: July 14, 2020
    Assignee: BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
    Inventor: Anne Margaret Pianca