Producing Visual Effects By Stimulation Patents (Class 607/54)
  • Patent number: 11096614
    Abstract: A method for providing a neural interface system. At least one primary metallization layer is deposited on a substrate. The primary metallization layer has a thickness. A monolayer of nanospheres is deposited in a substantially uniform distribution. The nanospheres contact an upper surface of the primary metallization layer. The upper surface of the primary metallization layer not contacted by the nanospheres is treated to form a plurality of undulating structures having a substantially uniform arrangement. The treating comprises etching recesses part-way through the thickness of exposed portions of the primary metallization layer from the upper surface thereof.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: August 24, 2021
    Assignee: Neuronexus Technologies, Inc.
    Inventor: John P. Seymour
  • Patent number: 11097105
    Abstract: A pulse current generation circuit (100) for neural stimulation includes an analogue signal receiving device (101) for receiving an analogue signal; an analogue-to-digital converter (102) for converting the analogue signal into a digital control signal; a current signal controller (103) for producing, according to the digital control signal, pulse current parameters for generating bidirectional pulse current signals; and a current generator (104) for generating, according to the pulse current parameters, bidirectional pulse current signals for neural stimulation, and the current generator can generate pulse currents of different precisions according to the pulse current parameters. In addition, the present invention further relates to a charge compensation circuit, a charge compensation method, and an implantable electrical retina stimulator using the pulse current generation circuit or the charge compensation circuit.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: August 24, 2021
    Assignee: SHENZHEN SIBIONICS TECHNOLOGY CO., LTD.
    Inventors: Bin Xia, Yu Zhao, Yu Lin, Xianwen Fang, Zhi Chen
  • Patent number: 11030749
    Abstract: An image-processing apparatus including: an image processor including circuitry or a hardware processor that operates under control of a stored program, the image processor being configured to execute processes including: a saliency-map calculating process that calculates saliency maps on a basis of at least one type of feature quantity obtained from an input image; a salient-region-identifying process that identifies a salient region by using the saliency maps; a salient-region-score-calculating process that calculates a score of the salient region by comparing a distribution of values of the saliency map in the salient region and a distribution of values of the saliency map in a region other than the salient region; and a saliency-evaluating process that evaluates the saliency of the salient region on a basis of the score.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: June 8, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Wataru Oniki
  • Patent number: 11007367
    Abstract: An electrotherapeutic device for treating a visual disease using microcurrent stimulation is provided. The device includes a signal generator in which a waveform controller digitally controls a waveform signal source so as to generate a waveform in which one or more waveform parameters (e.g., pulse width, pulse period, pulse position, pulse coding, peak current amplitude, duty cycle, and/or pulse shape) are varied in accordance with a protocol for treating a visual disease. The device also includes an applicator connected to the signal generator and configured to apply the waveform to at least one stimulation point within an eye region.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: May 18, 2021
    Assignee: NOVA OCULUS CANADA MANUFACTURING ULC
    Inventor: George D. O'Clock
  • Patent number: 10944290
    Abstract: A transmitter coil inductively couples to a receiver coil contained in a contact lens. In one approach, the transmitter coil is contained in a headgear, for example a head band. When the user wears the headgear, the transmitter coil is positioned on a side of the user's head and between the user's ear and the user's eye opening. In one implementation, a head band loops from one ear behind the user's head to the other ear, and also extends slightly forward of each ear. The transmitter coil(s) may be located in the portion of the headband that extends forward of each ear. This places the transmitter coil close to the receiver coil, typically within 40-50 mm of the user's eye opening, while still maintaining an unobtrusive aesthetic.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: March 9, 2021
    Assignee: Tectus Corporation
    Inventors: Ramin Mirjalili, Hawk Yin Pang, Richard Gioscia, Michael West Wiemer
  • Patent number: 10918856
    Abstract: A graphene bio-device for electrotherapy, includes: a flexible substrate; An electrode made of graphene on the flexible substrate; and an insulation layer on the graphene electrode; wherein the graphene bio-device comprises electrodes for ground, reference, recording and stimulation, wherein the graphene bio-device is measured corticography with low noise and alleviated seizure signals successfully by imposing electrical stimulation.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: February 16, 2021
    Assignee: gBrain Inc.
    Inventors: Sunggu Yang, Jong-Hyun Ahn, Jejung Kim, Wonho Lee, Minpyo Kang
  • Patent number: 10898713
    Abstract: The present invention is an improved system for use of eye tracking including spatial mapping percepts in a visual prosthesis by presenting an electrically induced precept through a visual prosthesis, requesting a subject look to the direction of the percept and tracking their eye movement. Eye movement is both faster and more accurate than asking a visual prosthesis user to point to the location of a percept. This method can be beneficial in a retinal prosthesis, but is particularly useful in a cortical visual prosthesis where visual cortex does not match the retinotopic map. Methods are presented for calibrating an eye tracker. Eye tracking hardware may also be used for blanking video information base on the subject's natural blink reflex.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: January 26, 2021
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Avraham I Caspi, Jessy D Dorn, Arup Roy, Robert J Greenberg
  • Patent number: 10895679
    Abstract: An optical structure and corresponding process of manufacture for light guide optical elements (LOEs) which guide light by reflection at major surfaces. The structure further includes light directing surfaces for coupling light out of the LOE, obliquely inclined with respect to the major surfaces. The optical structure is formed from a stack of multiple optically transparent layers each of which has a surface pattern of regions configured as light directing surfaces which are arranged in an X-Z plane in a spaced-apart relationship along at least the X-axis with optically transparent regions between them. The layers are stacked along a Y-axis so that each of the surface patterns is located at an interface between two adjacent layers and the patterns of the layers are aligned with a shift of a predetermined value along one or both of the X-axis and Z-axis.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 19, 2021
    Assignee: LUMUS LTD.
    Inventors: Yuval Ofir, Edgar Friedmann, Meir Tzion Bitan
  • Patent number: 10863897
    Abstract: The present technology relates to an image processing apparatus and an image processing method capable of suppressing an increase in a load on a subject and obtaining a captured image of the subject with higher image quality. An imaging unit reduces a light amount and performs imaging of the fundus of the eye so as to generate a plurality of fundus images. A biological information alignment processing unit aligns fundus images by using biological information of a subject. A super-resolution processing unit superimposes an aligned input image on a previous super-resolution result image so as to generate a new super-resolution result image. The super-resolution processing unit stores or outputs the super-resolution result image in a storage unit or from an output unit, and supplies the super-resolution result image to a super-resolution result image buffer so as to be stored.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: December 15, 2020
    Assignee: SONY CORPORATION
    Inventors: Kazuki Aisaka, Seiji Kobayashi, Takuya Kishimoto, Tomoyuki Ootsuki
  • Patent number: 10845621
    Abstract: A transmitter coil inductively couples to a receiver coil contained in a contact lens. In one approach, the transmitter coil is contained in a headgear, for example a head band. When the user wears the headgear, the transmitter coil is positioned on a side of the user's head and between the user's ear and the user's eye opening. In one implementation, a head band loops from one ear behind the user's head to the other ear, and also extends slightly forward of each ear. The transmitter coil(s) may be located in the portion of the headband that extends forward of each ear. This places the transmitter coil close to the receiver coil, typically within 40-50 mm of the user's eye opening, while still maintaining an unobtrusive aesthetic.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: November 24, 2020
    Assignee: Tectus Corporation
    Inventors: Ramin Mirjalili, Hawk Yin Pang, Richard Gioscia, Michael West Wiemer
  • Patent number: 10786670
    Abstract: The present invention is an improved visual prosthesis including a video processing unit with user controls optimized for use by blind individuals. The controls include easily identifiable shapes. The controls are programmable to provide improved usability with a simple tactile interface.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: September 29, 2020
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J Greenberg, Arup Roy
  • Patent number: 10780262
    Abstract: A method of assembling an implantable electrode array from a coupon (108) formed from plastically deformable material. Layers of material are disposed on the coupon to form the electrodes (48) and conductors (62) of one or more electrode arrays. Sections of the coupon on which the electrodes and conductors are removed, along with the electrodes and conductors to form the electrode arrays. The removed sections of the coupon thus function as plastically deformable carriers (74) for the arrays (40).
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: September 22, 2020
    Assignee: Stryker Corporation
    Inventors: Robert Brindley, John Janik
  • Patent number: 10610695
    Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: April 7, 2020
    Assignee: Oculeve, Inc.
    Inventors: James Donald Loudin, Manfred Franke, Daniel N. Hamilton, Anand Doraiswamy, Douglas Michael Ackermann
  • Patent number: 10576270
    Abstract: Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be placed entirely within a mouth of the user and atop the tongue of the user. An array of electro-tactile elements may be distributed on the body, wherein each of the electro-tactile elements is configured to stimulate an area of the tongue adjacent the electro-tactile element. A wireless receiver coupled to the body may be configured to receive stimulation information wirelessly from outside the mouth of the user. At least one processing unit coupled to the body may be configured to transform the received stimulation information into a stimulation signal for each of the electro-tactile elements, and to provide the stimulation signals to the electro-tactile elements.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: March 3, 2020
    Assignee: Colorado State University Research Foundation
    Inventors: John D. Williams, Joel A. Moritz, Leslie M. Stone-Roy
  • Patent number: 10503074
    Abstract: A method of making a device includes providing a fluorinated material layer over the device substrate having one or more target areas for patterning. One or more lift-off structures are formed at least in part by developing a first pattern of one or more open areas in the fluorinated material layer in alignment with the one or more target areas by contact with a developing agent including a fluorinated solvent which dissolves the fluorinated material at a first rate. After patterning, the lift-off structures are removed by contact with a lift-off agent including a fluorinated solvent wherein the lift-off agent dissolves the fluorinated material at a second rate that is at least 150 nm/sec and higher than the first rate.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: December 10, 2019
    Assignee: Orthogonal, Inc.
    Inventors: John Andrew Defranco, Charles Warren Wright, Douglas Robert Robello, Frank Xavier Byrne, Diane Carol Freeman, Terrence Robert O'Toole
  • Patent number: 10485482
    Abstract: A carbon nanotube (CNT) based electrode and method of making the same is disclosed. The CNT based electrode can have a microelectrode made substantially from a substantially inert metal, a first CNT sheet and a second CNT sheet, wherein the first and second CNT sheets are embedded in a collagen film.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: November 26, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Ray Baughman, Raquel Robles, Mario Romero-Ortega, Aswini Kanneganti, Young-tae Kim, Ryan Landrith
  • Patent number: 10459229
    Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: October 29, 2019
    Assignee: Magic Leap, Inc.
    Inventors: Nicole Elizabeth Samec, John Graham Macnamara, Christopher M. Harrises, Brian T. Schowengerdt, Rony Abovitz, Mark Baerenrodt
  • Patent number: 10445402
    Abstract: An apparatus comprises a memory, one or more hardware engines, and a processor. The memory may be configured to store a feature map pyramid comprising an original feature map and a plurality of scaled feature maps. The one or more hardware engines may be configured to perform pooling operations utilizing power of two down sampling. The processor may be configured to generate the feature map pyramid from the original feature map using said one or more hardware engines.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: October 15, 2019
    Assignee: Ambarella, Inc.
    Inventors: Yu Wang, Wei Fang, Leslie D. Kohn
  • Patent number: 10426958
    Abstract: Described here are devices and methods for increasing ocular mucin and other tear protein release using intranasally delivered electrical stimulation. Generally, the devices may deliver electrical stimulation to the nasal mucosa. Intranasal stimulation may trigger degranulation of conjunctival goblet cells, which in turn releases secretory mucins into the tear fluid. The intranasal stimulation may also trigger release of lysozyme, lactoferrin, and other tear proteins into the aqueous layer of the tear film. The methods may further comprise obtaining feedback relating to the efficacy of the delivered electrical stimulation by measuring impedance or an electromyogram (EMG) signal.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: October 1, 2019
    Assignee: Oculeve, Inc.
    Inventors: James Donald Loudin, Manfred Franke, Douglas Michael Ackermann
  • Patent number: 10426598
    Abstract: A visual image processing method is based on received spatial field information (302) from a spatial field sensor (116). A data store (804) is accessed, which contains a sensor map data structure (206) comprising a set of predefined regions (208) within a spatial field corresponding with the information received via the sensor input. Each predefined region is associated in the data structure with one or more of a set of stimuli (204) applicable to a biological visual system, and each stimulus corresponds with a visual percept (210). The spatial field information associated with each region is processed to generate stimulus control information which is applied to select, from within the sensor map data structure, stimuli from the set of stimuli for application to the biological visual system. Output stimulus signals (310) are generated, which are suitable for application to the biological visual system based upon the selected stimuli.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: October 1, 2019
    Assignee: Monash University
    Inventor: Wai Ho Li
  • Patent number: 10371945
    Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: August 6, 2019
    Assignee: Magic Leap, Inc.
    Inventors: Nicole Elizabeth Samec, John Graham Macnamara, Christopher M. Harrises, Brian T. Schowengerdt, Rony Abovitz, Mark Baerenrodt
  • Patent number: 10350410
    Abstract: A device is provided for stimulating neurons that includes a non-invasive stimulation unit that generates stimuli in multiple stimulation channels. The stimulation unit generates the stimuli to stimulate a neuron population in the brain and/or spinal cord of a patient using the stimulation channels in different locations. Moreover, the device includes a control unit that controls the stimulation unit to repeatedly generates sequences of the stimuli with the order of the stimulation channels in which stimuli are generated within a sequence being constant for 20 or more successively generated sequences before it is varied.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: July 16, 2019
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Peter Alexander Tass, Magteld Zeitler
  • Patent number: 10345590
    Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: July 9, 2019
    Assignee: Magic Leap, Inc.
    Inventors: Nicole Elizabeth Samec, John Graham Macnamara, Christopher M. Harrises, Brian T. Schowengerdt, Rony Abovitz, Mark Baerenrodt
  • Patent number: 10328255
    Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: June 25, 2019
    Assignee: Precision NeuroTechnologies LLC
    Inventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen
  • Patent number: 10293162
    Abstract: A method for providing electrical stimulation to a user, the method comprising: providing an electrical stimulation device, in communication with a controller, at a head region of the user; with the electrical stimulation device, providing a stimulation treatment having a waveform configured for neuromodulation in the user; with the controller, performing an adjustment to the stimulation treatment, wherein performing the adjustment includes: generating a transformed waveform with application of a transfer function to the waveform, wherein the transfer function scales the waveform and selectively attenuates extreme waveform values while maintaining a frequency characteristic of the waveform in the transformed waveform; and applying the transformed waveform with the electrical stimulation device, thereby modulating the stimulation treatment.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: May 21, 2019
    Assignee: Halo Neuro, Inc.
    Inventor: Brett Wingeier
  • Patent number: 10272245
    Abstract: A neural sensing method includes the steps of: configuring an array of sensing units on a retina of a user, each of the sensing units detecting a signal and generating a sensed signal; generating a control signal by a control signal generator and transmitting the control signal to at least one electrode installed in a periphery of each of the sensing units; isolating each of the sensed signals by the control signal, thereby suppressing the mutual interference between the sensed signals by the control signal; and generating and outputting a processed signal to at least one neuron via a signal processing module with reference to the control signal and the sensed signals. The control signal has a signal strength lower than the sensing threshold of the at least one neuron.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: April 30, 2019
    Inventor: Po-Kang Lin
  • Patent number: 10272244
    Abstract: Apparatus is provided including an implantable retinal stimulator, for implantation on a retina of an eye, and including (i) an electrode array including electrodes; (ii) a plurality of photosensors; and (iii) driving circuitry, configured to drive the electrodes to apply currents to the retina. The apparatus further includes an interface member disposed at an outer surface of the implantable retinal stimulator, e.g., a peripheral member surrounding at least a portion of the implantable retinal stimulator. The apparatus additionally includes a frame, (i) shaped and sized to couple to the peripheral member and to surround the implantable retinal stimulator at least in part, and (ii) shaped to define at least a first anchoring element receiving portion. An anchoring element is shaped and sized to be positioned in the anchoring element receiving portion and to penetrate scleral tissue of the subject. Other applications are also described.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 30, 2019
    Assignee: NANO RETINA LTD.
    Inventors: Boris Degtiar, Rani Mendelewicz, Yaakov Milstain, Yossi Gross, Dorit Raz Prag, Matan Zehavi, David Rigler
  • Patent number: 10219937
    Abstract: A system and method of treating hyperactivity of an eyelid closing muscle in a subject includes providing a stimulation system in the subject with the hyperactivity of the eyelid closing muscle, sensing an activity of the eyelid closing muscle, and selectively stimulating eyelid opening muscle(s) or innervating nerves, eyelid opening reflexes, or eyelid opening reflexes in non-muscular tissue, using the stimulation system, without substantially activating the eyelid closing muscle. The system and method evokes eyelid movement in the subject.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: March 5, 2019
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventor: Werner Lindenthaler
  • Patent number: 10155108
    Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: December 18, 2018
    Assignee: OCULEVE, INC.
    Inventors: Douglas Michael Ackermann, James Donald Loudin
  • Patent number: 10154235
    Abstract: A device for displaying an image sequence in the form of a pixel matrix, includes a control unit coupled to a projector. The control unit includes an input interface designed to receive asynchronous information representing, for each pixel of the matrix, events concerning the pixel, and a processor designed to control the activation of each pixel of the matrix at moments determined by the respective events indicated by the asynchronous information for the pixel. The projector is disposed on a support so as to illuminate the light receptors of the eye when the device is in use and is designed to project a light flux corresponding to the pixels activated by the control unit.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: December 11, 2018
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS
    Inventors: Ryad Benosman, Guillaume Chenegros, Serge Picaud, Siohoi Ieng, Jose-Alain Sahel
  • Patent number: 10117740
    Abstract: An eye-mountable device is provided that includes a battery or other local power source and that can wirelessly power one or more intraocular devices using power from the battery. The eye-mountable device could be provided as a contact lens. The eye-mountable device could provide power to an intraocular device by emitting radio frequency energy, time-varying electrical fields through the conductive medium of the eye, or optical energy. The intraocular device could include an electronic lens configured to provide a controllable optical power to the eye. The intraocular device could include sensors configured to detect accommodation forces exerted by muscles of the eye; such detected forces could be used to control an electronic lens of the intraocular device or an electronic lens of the eye-mountable device. The battery could be rechargeable and the eye-mountable device could include instrumentation for receiving power to recharge the battery.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: November 6, 2018
    Assignee: Verily Life Sciences LLC
    Inventor: Shungneng Lee
  • Patent number: 10052476
    Abstract: Improved low-cost, highly reliable methods for increasing the electrochemical surface area of neural electrodes are described. A mono-layer of polymeric nanospheres is first deposited on a metallization supported on a dielectric substrate. The nanospheres self-assemble into generally repeating lattice forms with interstitial space between them. Then, the geometric surface area of the metallization material is increased by either selectively etching part-way into its depth at the interstitial space between adjacent nanospheres. Another technique is to deposit addition metallization material into the interstitial space. The result is undulation surface features provided on the exposed surface of the metallization. This helps improve the electrochemical surface area when the treated metallizations are fabricated into electrodes.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: August 21, 2018
    Assignee: NeuroNexus Technologies, Inc.
    Inventor: John P. Seymour
  • Patent number: 10013599
    Abstract: An apparatus for improving performance of a retinal implant may include processing circuitry. The processing circuitry may be configured to receive image data corresponding to a camera field of view, determine whether a particular object is detected within the camera field of view, perform image data processing to enable a representation of a portion of the image data corresponding to an implant field of view to be provided on a retinal implant where the implant field of view is smaller than the camera field of view, and, responsive to the particular object being located outside the implant field of view, provide a directional indicator in the implant field of view to indicate a location of the particular object relative to the implant field of view.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: July 3, 2018
    Assignee: The Johns Hopkins University
    Inventors: Derek M. Rollend, Kapil D. Katyal, Kevin C. Wolfe, Dean M. Kleissas, Matthew P. Para, Paul E. Rosendall, John B. Helder, Philippe M. Burlina, Duane C. Cornish, Ryan J. Murphy, Matthew S. Johannes, Arup Roy, Seth D. Billings, Jonathan M. Oben, Robert J. Greenberg
  • Patent number: 10004635
    Abstract: A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: June 26, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventor: Malik Y. Kahook
  • Patent number: 9987167
    Abstract: An input signal (f) representative of a scene to be viewed comprises, for each pixel of a matrix of pixels, an event-based asynchronous-signal sequence obtained as a function of variations of light relating to the pixel in the scene. This input signal is transformed spatially within the matrix of pixels and temporally along the signal sequences to generate respective control signals (S) for pixel zones of a device for aiding vision (20).
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: June 5, 2018
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
    Inventors: Henri Lorach, Ryad Benosman, Jose Sahel, Srege Picaud
  • Patent number: 9974954
    Abstract: The present invention is an improved visual prosthesis including a video processing unit with user controls optimized for use by blind individuals. The controls include easily identifiable shapes. The controls are programmable to provide improved usability with a simple tactile interface.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: May 22, 2018
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Arup Roy
  • Patent number: 9919140
    Abstract: An implantable oxygenator may have a configuration that is suitable for implantation within a human body be implanted within a human body, such as within a human eye. The implantable oxygenator may include an electrolyte reservoir having a configuration suitable for storing electrolyte and an electrolysis system having a configuration that performs electrolysis on a portion of the electrolyte, thereby producing oxygen in the region of the electrolysis system.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: March 20, 2018
    Assignee: University of Southern California
    Inventors: Mark S. Humayun, Karthik Murali, Ramiro Magalhaes Ribeiro, Yu-chong Tai, Nicholas Scianmarello
  • Patent number: 9919156
    Abstract: The present invention is a wireless transmission system for a prosthetic apparatus including a mounting system to be worn on a body, a wound wire transmission coil mounted to the mounting system and sending a stimulation signal, an implantable receiving coil receiving the stimulation signal and connected to a hermetic electronics package, an implantable telemetry transmitting coil connected to the hermetic electronics package, and a telemetry receiving coil printed on a printed circuit board, mounted to the mounting system and receiving the telemetry signal.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: March 20, 2018
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Kelly H McClure, Richard A Castro, Arup Roy, Scott Loftin, Rongqing Dai, Robert J Greenberg, Sumit Yadav
  • Patent number: 9907969
    Abstract: An external device is provided for use with an intraocular device configured to be implanted entirely in an eye of a subject. The external device includes a mount configured to be placed in front of the eye and a sensor coupled to the mount and configured to sense a level of ambient light. The external device additionally includes an external power source coupled to the mount and configured to (i) emit toward the eye non-visible light that is outside of 380-750 nm, and (ii) modulate the non-visible light based on the level of ambient light sensed by the sensor. Other application are also described.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: March 6, 2018
    Assignee: NANO-RETINA, INC.
    Inventors: Ra'anan Gefen, Yossi Gross, Tuvia Liran, Shai Vaingast
  • Patent number: 9884180
    Abstract: Apparatus, systems and methods employing contact lens as power source for powering a retinal implant are provided. In an aspect, a contact lens includes a substrate that forms at least part of a body of the contact lens and a circuit disposed on or within the substrate comprising. The circuit includes a power harvesting component configured to receive energy in a first form from an external power source and convert the energy from the first form to a second form and an energy transfer component configured to transmit the energy in the second form to device remote from the contact lens when the contact lens is worn over an eye.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: February 6, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Harvey Ho, Babak Amirparviz
  • Patent number: 9861820
    Abstract: The present invention consists of an implantable device with a hermetic electronics package that houses electronics. The hermetic package is attached to a flexible circuit electrode array having its electrodes arranged in a trapezoidal electrode array field that is suitable to stimulate the visual cortex. The hermetic electronics package is provided with a fixation structure that secures, protects and dissipates heat from the electronics package. The entire implantable device can be entirely implanted within the head.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: January 9, 2018
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Neil Talbot, Proyag Datta, Dustin Tobey, Dao Min Zhou, Jessy Dorn
  • Patent number: 9835879
    Abstract: A system for attaching a device to a glasses frame includes a spring clip that applies pressure to two sides of the glasses frame, and a magnet for attaching the device thereto. The device may attach directly to the magnet, or via a slide-on attachment piece. The spring clip may include a spring arm having distal ends that assist the spring clip in applying pressure to the glasses frames.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: December 5, 2017
    Assignee: OmniVision Technologies, Inc.
    Inventor: Yen-Sung Wang
  • Patent number: 9823737
    Abstract: Various embodiments of an intelligent augmented reality personal assistant apparatus integrated (or co-packaged) with an eye motion sensor, a microprocessor or an intelligent microprocessor and an intelligent rendering algorithm are disclosed. Such an augmented reality personal assistant apparatus can interpret/analyze/learn activities, communication or contextual information of a user and recommend relevant and useful information to the user.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: November 21, 2017
    Inventors: Mohammad A Mazed, Sayeeda Mazed
  • Patent number: 9802036
    Abstract: A device for contacting and/or electrically stimulating biological tissue by means of at least one electrode has at least a first unit, on which the at least one electrode is provided and which is configured for implantation in a human or animal body, a second unit, for supplying the first unit with electrical energy, and at least a first and a second conductive track for the voltage supply of the first unit. The first and second conductive tracks are respectively electrically connected to the first and second units and are at different voltage potentials. Spatially between the first and second conductive tracks, at least a first additional conductive track is arranged that is functionally not involved in the voltage supply of the first unit.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: October 31, 2017
    Assignee: RETINA IMPLANT AG
    Inventor: Martin Kokelmann
  • Patent number: 9795786
    Abstract: The present invention relates to a saliency-based apparatus and methods for visual prostheses. A saliency-based component processes video data output by a digital signal processor before the video data are input to the retinal stimulator. In a saliency-based method, an intensity stream is extracted from an input image, feature maps based on the intensity stream are developed, plural most salient regions of the input image are detected and one of the regions is selected as a highest saliency region.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 24, 2017
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert Greenberg, Alan Horsager, Mark S. Humayun, Kelly H. McClure, Matthew J. McMahon, Peter Meilstrup, Neha Parikh, Arup Roy, James D. Weiland, Chunhong Zhou
  • Patent number: 9737711
    Abstract: A system and method is provided for preferentially stimulating a portion of neural tissue including a first type of neurons and a second type of neurons. The method includes defining a waveform characterizing an electrical stimulus, wherein the waveform includes an amplitude-modulated wave of the electric stimulus. The method also includes applying the electrical stimulus having the defined waveform to a stimulating element located in proximity to the neural tissue to selectively activate the first type of neurons while leaving the second type of neurons one of substantially unaffected and suppressed in response to the electrical stimulus.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: August 22, 2017
    Assignee: The General Hospital Corporation
    Inventors: Perry Twyford, Changsi Cai, Shelley Fried
  • Patent number: 9700722
    Abstract: A visual prosthesis in the form of a retinal implant, which is distinguished by the least possible space requirement inside the eye, is achieved by a visual prosthesis having an intraocular implant and an extraocular implant, which supplies the intraocular implant with energy and controls it. Virtually all the electronic components, which do not necessarily need to be accommodated with the intraocular implant inside the eye, can be arranged outside the eyeball, for example on the sclera. In this way, the space requirement of the stimulation system inside the eye is reduced and the operative intervention for implanting the stimulation system inside the eye is kept as small as possible. A bidirectional inductive interface between an extracorporeal part of the visual prosthesis and an intracorporeal part, including the intraocular and extraocular implants, via which a current supply and bidirectional data transmission can be carried out is provided.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: July 11, 2017
    Assignee: Pixium Vision SA
    Inventors: Thomas Zehnder, Hans-Jurgen Tiedtke
  • Patent number: 9694180
    Abstract: A method of testing subjects' perception of complex shapes created by patterned multi-electrode direct stimulation of a retinal prosthesis is described. The complex shapes can be geometric shapes or characters such as letters of the alphabet and numbers.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: July 4, 2017
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Dennis C. Cheung, Jessy Dorn
  • Patent number: 9669209
    Abstract: A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: June 6, 2017
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Jordan Neysmith, Robert Greenberg, James Little, Brian Mech, Neil Talbot, Qingfang Yao, Dao Min Zhou
  • Patent number: 9656078
    Abstract: In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: May 23, 2017
    Inventors: Yuri P. Danilov, Mitchell E. Tyler, Kurt A. Kaczmarek